{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:51:05Z","timestamp":1785552665939,"version":"3.56.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nanomedicine: Nanotechnology, Biology and Medicine"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.nano.2017.12.017","type":"journal-article","created":{"date-parts":[[2018,1,6]],"date-time":"2018-01-06T17:25:52Z","timestamp":1515259552000},"page":"713-723","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"title":["Redox-responsive micelles from disulfide bond-bridged hyaluronic acid-tocopherol succinate for the treatment of melanoma"],"prefix":"10.1016","volume":"14","author":[{"given":"Junping","family":"Xia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunai","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birendra","family":"Chaurasiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiasheng","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Webster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunmeng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nano.2017.12.017_bb0005","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/j.nano.2017.05.001","article-title":"Ion-paired pirenzepine-loaded micelles as an ophthalmic delivery system for the treatment of myopia","volume":"13","author":"Li","year":"2017","journal-title":"Nanomedicine"},{"key":"10.1016\/j.nano.2017.12.017_bb0010","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.1039\/C4PY01422G","article-title":"Paclitaxel-loaded cholesterol-conjugated polyoxyethylene sorbitol oleate polymeric micelles for glioblastoma therapy across the blood-brain barrier","volume":"6","author":"Li","year":"2015","journal-title":"Polym Chem"},{"key":"10.1016\/j.nano.2017.12.017_bb0015","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.ijpharm.2015.01.009","article-title":"Paclitaxel-loaded micelles enhance transvascular permeability and retention of nanomedicines in tumors","volume":"479","author":"Danhier","year":"2015","journal-title":"Int J Pharm"},{"key":"10.1016\/j.nano.2017.12.017_bb0020","doi-asserted-by":"crossref","first-page":"783","DOI":"10.2174\/1389200217666160607093347","article-title":"Influence of Tumor Microenvironment on the Distribution and Elimination of Nano-formulations","volume":"17","author":"Chaurasiya","year":"2016","journal-title":"Curr Drug Metab"},{"key":"10.1016\/j.nano.2017.12.017_bb0025","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1021\/mp400747k","article-title":"Interaction between cell-penetrating peptides and acid-sensitive anionic oligopeptides as a model for the design of targeted drug carriers","volume":"11","author":"Sun","year":"2014","journal-title":"Mol Pharm"},{"key":"10.1016\/j.nano.2017.12.017_bb0030","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1016\/j.nano.2017.07.009","article-title":"Noninvasive nanoparticle strategies for brain tumor targeting","volume":"13","author":"Sun","year":"2017","journal-title":"Nanomedicine"},{"key":"10.1016\/j.nano.2017.12.017_bb0035","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jconrel.2017.01.046","article-title":"Intracellular responsive dual delivery by endosomolytic polyplexes carrying DNA anchored porous silicon nanoparticles","volume":"249","author":"Shahbazi","year":"2017","journal-title":"J Control Release"},{"key":"10.1016\/j.nano.2017.12.017_bb0040","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jconrel.2017.01.042","article-title":"Tumor-targeted pH\/redox dual-sensitive unimolecular nanoparticles for efficient siRNA delivery","volume":"259","author":"Chen","year":"2017","journal-title":"J Control Release"},{"key":"10.1016\/j.nano.2017.12.017_bb0045","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.carbpol.2016.11.094","article-title":"Efficient delivery of paclitaxel into ASGPR over-expressed cancer cells using reversibly stabilized multifunctional pullulan nanoparticles","volume":"159","author":"Huang","year":"2017","journal-title":"Carbohydr Polym"},{"key":"10.1016\/j.nano.2017.12.017_bb0050","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1093\/jn\/134.3.489","article-title":"Glutathione metabolism and its implications for health","volume":"134","author":"Wu","year":"2004","journal-title":"J Nutr"},{"key":"10.1016\/j.nano.2017.12.017_bb0055","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1016\/j.biomaterials.2009.01.026","article-title":"Reduction-sensitive polymers and bioconjugates for biomedical applications","volume":"30","author":"Meng","year":"2009","journal-title":"Biomaterials"},{"key":"10.1016\/j.nano.2017.12.017_bb0060","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1021\/mp800024g","article-title":"Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor","volume":"5","author":"Platt","year":"2007","journal-title":"Mol Pharm"},{"key":"10.1016\/j.nano.2017.12.017_bb0065","doi-asserted-by":"crossref","first-page":"81668","DOI":"10.1039\/C5RA16757D","article-title":"Synthesis and characterization of hyaluronic acid-platinum(IV) nanoconjugate with enhanced antitumor response and reduced adverse effects","volume":"5","author":"Ling","year":"2015","journal-title":"RSC Adv"},{"key":"10.1016\/j.nano.2017.12.017_bb0070","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1039\/C4PY01592D","article-title":"Tumor-targeting delivery of hyaluronic acid-platinum(iv) nanoconjugate to reduce toxicity and improve survival","volume":"6","author":"Ling","year":"2015","journal-title":"Polym Chem"},{"key":"10.1016\/j.nano.2017.12.017_bb0075","doi-asserted-by":"crossref","first-page":"46464","DOI":"10.1039\/C5RA03085D","article-title":"Co-delivery of siRNA and paclitaxel into cancer cells by hyaluronic acid modified redox-sensitive disulfide-crosslinked PLGA-PEI nanoparticles","volume":"5","author":"Shen","year":"2015","journal-title":"RSC Adv"},{"key":"10.1016\/j.nano.2017.12.017_bb0080","doi-asserted-by":"crossref","first-page":"39896","DOI":"10.1039\/C5RA27532F","article-title":"Mechanisms of cellular uptake with hyaluronic acid\u2014octadecylamine micelles as drug delivery nanocarriers","volume":"6","author":"Qiu","year":"2016","journal-title":"RSC Adv"},{"key":"10.1016\/j.nano.2017.12.017_bb0085","doi-asserted-by":"crossref","first-page":"e73","DOI":"10.1016\/j.jconrel.2015.05.122","article-title":"Hyaluronic acid derivative-modified liposomes as pH-sensitive anticancer drug delivery system","volume":"213","author":"Miyazaki","year":"2015","journal-title":"J Control Release"},{"key":"10.1016\/j.nano.2017.12.017_bb0090","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jconrel.2016.03.012","article-title":"Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation","volume":"229","author":"Ravar","year":"2016","journal-title":"J Control Release"},{"key":"10.1016\/j.nano.2017.12.017_bb0095","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.jconrel.2014.06.049","article-title":"Target-specific delivery of siRNA by stabilized calcium phosphate nanoparticles using dopa\u2013hyaluronic acid conjugate","volume":"192","author":"Min","year":"2014","journal-title":"J Control Release"},{"key":"10.1016\/j.nano.2017.12.017_bb0100","doi-asserted-by":"crossref","first-page":"7121","DOI":"10.1016\/j.biomaterials.2014.04.096","article-title":"Tumor-specific delivery of siRNA using supramolecular assembly of hyaluronic acid nanoparticles and 2b RNA-binding protein\/siRNA complexes","volume":"35","author":"Choi","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.nano.2017.12.017_bb0105","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.biomaterials.2013.10.014","article-title":"Non-viral DNA delivery from porous hyaluronic acid hydrogels in mice","volume":"35","author":"Tokatlian","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.nano.2017.12.017_bb0110","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jconrel.2014.03.009","article-title":"Vitamin E-based nanomedicines for anti-cancer drug delivery","volume":"182","author":"Duhem","year":"2014","journal-title":"J Control Release"},{"key":"10.1016\/j.nano.2017.12.017_bb0115","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1080\/07315724.2003.10719283","article-title":"Alpha-tocopheryl succinate, the most effective form of vitamin E for adjuvant cancer treatment: a review","volume":"22","author":"Prasad","year":"2003","journal-title":"J Am Coll Nutr"},{"key":"10.1016\/j.nano.2017.12.017_bb0120","first-page":"1114","article-title":"Anticancer mechanisms of vitamin E succinate","volume":"28","author":"Dong","year":"2009","journal-title":"Ai Zheng"},{"key":"10.1016\/j.nano.2017.12.017_bb0125","first-page":"550","article-title":"Effects of tocopherol (vitamin E) acid succinate on morphological alterations and growth inhibition in melanoma cells in culture","volume":"42","author":"Prasad","year":"1982","journal-title":"Cancer Res"},{"key":"10.1016\/j.nano.2017.12.017_bb0130","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1067\/msy.2002.119191","article-title":"Vitamin E inhibits melanoma growth in mice","volume":"131","author":"Malafa","year":"2002","journal-title":"Surgery"},{"key":"10.1016\/j.nano.2017.12.017_bb0135","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.urology.2006.08.318","article-title":"MP-08.11 : Vitamin E succinate inactivates androgen receptor and enhances the cytotoxic effects of paclitaxel in prostate cancer cells","volume":"68","author":"Ohigashi","year":"2006","journal-title":"Urology"},{"key":"10.1016\/j.nano.2017.12.017_bb0140","first-page":"307","article-title":"Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels","volume":"62","author":"Kuppusamy","year":"2002","journal-title":"Cancer Res"},{"key":"10.1016\/j.nano.2017.12.017_bb0145","doi-asserted-by":"crossref","first-page":"4101","DOI":"10.1039\/b900456d","article-title":"Self-assembled hyaluronic acid nanoparticles as a potential drug carrier for cancer therapy: Synthesis, characterization, and in vivo biodistribution","volume":"19","author":"Choi","year":"2009","journal-title":"J Mater Chem"},{"key":"10.1016\/j.nano.2017.12.017_bb0150","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1007\/BF02574523","article-title":"Inhibition of angiogenesis and promotion of melanoma dormancy by vitamin E succinate","volume":"9","author":"Malafa","year":"2002","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.nano.2017.12.017_bb0155","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/S0962-8924(99)01608-6","article-title":"Getting across the nuclear pore complex","volume":"9","author":"Talcott","year":"1999","journal-title":"Trends Cell Biol"}],"updated-by":[{"DOI":"10.1016\/j.nano.2025.102807","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000}}],"container-title":["Nanomedicine: Nanotechnology, Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1549963418300029?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1549963418300029?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:29:24Z","timestamp":1740616164000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1549963418300029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S1549963418300029"],"URL":"https:\/\/doi.org\/10.1016\/j.nano.2017.12.017","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.nano.2025.102807","asserted-by":"object"}]},"ISSN":["1549-9634"],"issn-type":[{"value":"1549-9634","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Redox-responsive micelles from disulfide bond-bridged hyaluronic acid-tocopherol succinate for the treatment of melanoma","name":"articletitle","label":"Article Title"},{"value":"Nanomedicine: Nanotechnology, Biology and Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nano.2017.12.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}