{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T11:57:34Z","timestamp":1780315054160,"version":"3.54.1"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003443","name":"Ministry of Education and Science of the Russian Federation","doi-asserted-by":"publisher","award":["FSEG-2022-0012"],"award-info":[{"award-number":["FSEG-2022-0012"]}],"id":[{"id":"10.13039\/501100003443","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002261","name":"Russian Foundation for Basic Research","doi-asserted-by":"publisher","award":["22-75-10011"],"award-info":[{"award-number":["22-75-10011"]}],"id":[{"id":"10.13039\/501100002261","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nanomedicine: Nanotechnology, Biology and Medicine"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.nano.2024.102753","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T16:21:05Z","timestamp":1715271665000},"page":"102753","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Comparison of passive targeted delivery of inorganic and organic nanocarriers among different types of tumors"],"prefix":"10.1016","volume":"59","author":[{"given":"Alisa S.","family":"Postovalova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulia A.","family":"Tishchenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria S.","family":"Istomina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timofey E.","family":"Karpov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergei A.","family":"Shipilovskikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Akhmetova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Rogova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina V.","family":"Gavrilova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander S.","family":"Timin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.nano.2024.102753_bb0005","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1080\/02652048.2021.1942275","article-title":"Nanoparticles in nanomedicine: a comprehensive updated review on current status, challenges and emerging opportunities","volume":"38","author":"Abdel-Mageed","year":"2021","journal-title":"J Microencapsul"},{"issue":"5","key":"10.1016\/j.nano.2024.102753_bb0010","doi-asserted-by":"crossref","DOI":"10.1038\/natrevmats.2016.14","article-title":"Analysis of nanoparticle delivery to tumours","volume":"1","author":"Wilhelm","year":"2016","journal-title":"Nat Rev Mater"},{"key":"10.1016\/j.nano.2024.102753_bb0015","first-page":"1","article-title":"Nano-therapeutics: the upcoming nanomedicine to treat cancer","author":"Khan","year":"2024","journal-title":"IUBMB Life"},{"issue":"24","key":"10.1016\/j.nano.2024.102753_bb0020","doi-asserted-by":"crossref","first-page":"4494","DOI":"10.3390\/nano12244494","article-title":"Nanoparticles in drug delivery: from history to therapeutic applications","volume":"12","author":"Afzal","year":"2022","journal-title":"Nanomaterials"},{"issue":"6","key":"10.1016\/j.nano.2024.102753_bb0025","doi-asserted-by":"crossref","first-page":"430","DOI":"10.2174\/1389200220666181127102720","article-title":"Nanotherapeutics for the treatment of cancer and arthritis","volume":"20","author":"Patel","year":"2019","journal-title":"Curr Drug Metab"},{"issue":"1","key":"10.1016\/j.nano.2024.102753_bb0030","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/nrc.2016.108","article-title":"Cancer nanomedicine: progress, challenges and opportunities","volume":"17","author":"Shi","year":"2017","journal-title":"Nat Rev Cancer"},{"issue":"1","key":"10.1016\/j.nano.2024.102753_bb0035","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201901223","article-title":"Size-dependent EPR effect of polymeric nanoparticles on tumor targeting","volume":"9","author":"Kang","year":"2020","journal-title":"Adv Healthc Mater"},{"issue":"5","key":"10.1016\/j.nano.2024.102753_bb0040","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/s41563-019-0566-2","article-title":"The entry of nanoparticles into solid tumours","volume":"19","author":"Sindhwani","year":"2020","journal-title":"Nat Mater"},{"issue":"1","key":"10.1016\/j.nano.2024.102753_bb0045","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202103836","article-title":"Tumor-microenvironment-responsive nanomedicine for enhanced cancer immunotherapy","volume":"9","author":"Peng","year":"2022","journal-title":"Adv Sci"},{"key":"10.1016\/j.nano.2024.102753_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2023.215051","article-title":"Current understanding of passive and active targeting nanomedicines to enhance tumor accumulation","volume":"481","author":"Chen","year":"2023","journal-title":"Coord Chem Rev"},{"key":"10.1016\/j.nano.2024.102753_bb0055","article-title":"Active targeting drug delivery nanocarriers: ligands","volume":"19","author":"Salahpour Anarjan","year":"2019","journal-title":"Nano-Struct Nano-Objects"},{"issue":"5","key":"10.1016\/j.nano.2024.102753_bb0060","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1038\/s41563-020-0672-1","article-title":"Active transcytosis and new opportunities for cancer nanomedicine","volume":"19","author":"Pandit","year":"2020","journal-title":"Nat Mater"},{"issue":"3","key":"10.1016\/j.nano.2024.102753_bb0065","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/s44222-024-00154-9","article-title":"The mechanisms of nanoparticle delivery to solid tumours","volume":"2","author":"Nguyen","year":"2024","journal-title":"Nat Rev Bioeng"},{"key":"10.1016\/j.nano.2024.102753_bb0070","article-title":"Theranostic hyaluronan coated EDTA modified magnetic mesoporous silica nanoparticles for targeted delivery of cisplatin","volume":"77","author":"Zarkesh","year":"2022","journal-title":"J Drug Deliv Sci Technol"},{"issue":"33","key":"10.1016\/j.nano.2024.102753_bb0075","doi-asserted-by":"crossref","first-page":"38048","DOI":"10.1021\/acsami.2c05750","article-title":"Size-controllable DNA origami-stacked gold nanoparticles for deep tumor-penetrating therapy","volume":"14","author":"Gu","year":"2022","journal-title":"ACS Appl Mater Interfaces"},{"issue":"3","key":"10.1016\/j.nano.2024.102753_bb0080","doi-asserted-by":"crossref","DOI":"10.1002\/mabi.202100404","article-title":"Peptide modified albumin\u2013paclitaxel nanoparticles for improving chemotherapy and preventing metastasis","volume":"22","author":"Fu","year":"2022","journal-title":"Macromol Biosci"},{"issue":"3","key":"10.1016\/j.nano.2024.102753_bb0085","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1021\/acs.bioconjchem.0c00048","article-title":"Hyaluronic acid-decorated glycol chitosan nanoparticles for pH-sensitive controlled release of doxorubicin and celecoxib in nonsmall cell lung cancer","volume":"31","author":"Lee","year":"2020","journal-title":"Bioconjug Chem"},{"issue":"3","key":"10.1016\/j.nano.2024.102753_bb0090","doi-asserted-by":"crossref","first-page":"380","DOI":"10.3892\/mco.2014.246","article-title":"Combined therapeutic efficacy of 188Re-liposomes and sorafenib in an experimental colorectal cancer liver metastasis model by intrasplenic injection of C26-luc murine colon cancer cells","volume":"2","author":"Chang","year":"2014","journal-title":"Mol Clin Oncol"},{"issue":"39","key":"10.1016\/j.nano.2024.102753_bb0095","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202002162","article-title":"Nanoparticles in the biological context: surface morphology and protein corona formation","volume":"16","author":"Richtering","year":"2020","journal-title":"Small"},{"issue":"7","key":"10.1016\/j.nano.2024.102753_bb0100","doi-asserted-by":"crossref","first-page":"6766","DOI":"10.1166\/jnn.2016.11372","article-title":"Size effect of mesoporous and hollow silica nanoparticles on solid tumor targeting and penetration","volume":"16","author":"Li","year":"2016","journal-title":"J Nanosci Nanotechnol"},{"issue":"19","key":"10.1016\/j.nano.2024.102753_bb0105","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.2174\/092986712800784702","article-title":"Drug-loaded nanocarriers: passive targeting and crossing of biological barriers","volume":"19","author":"Rabanel","year":"2012","journal-title":"Curr Med Chem"},{"issue":"1\u20133","key":"10.1016\/j.nano.2024.102753_bb0110","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0168-3659(01)00309-1","article-title":"Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS","volume":"74","author":"Maeda","year":"2001","journal-title":"J Control Release"},{"key":"10.1016\/j.nano.2024.102753_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114449","article-title":"Strategies to enhance drug delivery to solid tumors by harnessing the EPR effects and alternative targeting mechanisms","volume":"188","author":"Zi","year":"2022","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.nano.2024.102753_bb0120","doi-asserted-by":"crossref","first-page":"7291","DOI":"10.2147\/IJN.S146315","article-title":"Effective use of nanocarriers as drug delivery systems for the treatment of selected tumors","volume":"12","author":"ud Din","year":"2017","journal-title":"Int J Nanomedicine"},{"issue":"15","key":"10.1016\/j.nano.2024.102753_bb0125","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1002\/adhm.201500441","article-title":"Effect of shape, size, and aspect ratio on nanoparticle penetration and distribution inside solid tissues using 3D spheroid models","volume":"4","author":"Agarwal","year":"2015","journal-title":"Adv Healthc Mater"},{"issue":"24","key":"10.1016\/j.nano.2024.102753_bb0130","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201808146","article-title":"Biodegradable nanoparticles of polyacrylic acid\u2013stabilized amorphous CaCO3 for tunable pH-responsive drug delivery and enhanced tumor inhibition","volume":"29","author":"Xu","year":"2019","journal-title":"Adv Funct Mater"},{"issue":"12","key":"10.1016\/j.nano.2024.102753_bb0135","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.7150\/thno.17098","article-title":"Size dependent kinetics of gold nanorods in EPR mediated tumor delivery","volume":"6","author":"Tong","year":"2016","journal-title":"Theranostics"},{"issue":"7\u20138","key":"10.1016\/j.nano.2024.102753_bb0140","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1049\/nbt2.12094","article-title":"The role of size in PEGylated liposomal doxorubicin biodistribution and anti-tumour activity","volume":"16","author":"Dadpour","year":"2022","journal-title":"IET Nanobiotechnol"},{"issue":"5","key":"10.1016\/j.nano.2024.102753_bb0145","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1021\/acs.nanolett.7b00021","article-title":"Mediating passive tumor accumulation through particle size, tumor type, and location","volume":"17","author":"Perry","year":"2017","journal-title":"Nano Lett"},{"key":"10.1016\/j.nano.2024.102753_bb0150","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.biomaterials.2016.08.030","article-title":"Investigating the effect of tumor vascularization on magnetic targeting in vivo using retrospective design of experiment","volume":"106","author":"Mei","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.nano.2024.102753_bb0155","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jconrel.2017.06.006","article-title":"Comprehensive study of the drug delivery properties of poly(l-lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice","volume":"261","author":"Shalgunov","year":"2017","journal-title":"J Control Release"},{"issue":"1","key":"10.1016\/j.nano.2024.102753_bb0160","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202205474","article-title":"Engineered macrophages: a safe-by-design approach for the tumor targeting delivery of sub-5 nm gold nanoparticles","volume":"19","author":"Xu","year":"2023","journal-title":"Small"},{"issue":"22","key":"10.1016\/j.nano.2024.102753_bb0165","doi-asserted-by":"crossref","first-page":"25599","DOI":"10.1021\/acsami.1c02155","article-title":"Calcium carbonate core\u2013shell particles for incorporation of 225Ac and their application in local \u03b1-radionuclide therapy","volume":"13","author":"Muslimov","year":"2021","journal-title":"ACS Appl Mater Interfaces"},{"issue":"6","key":"10.1016\/j.nano.2024.102753_bb0170","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1002\/tcr.202000104","article-title":"Silica-based nanoparticles as drug delivery vehicles for prostate cancer treatment","volume":"21","author":"Tiburcius","year":"2021","journal-title":"Chem Rec"},{"issue":"3","key":"10.1016\/j.nano.2024.102753_bb0175","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0168-3659(02)00211-0","article-title":"Lipophilic drug loaded nanospheres prepared by nanoprecipitation: effect of formulation variables on size, drug recovery and release kinetics","volume":"83","author":"Chorny","year":"2002","journal-title":"J Control Release"},{"issue":"22","key":"10.1016\/j.nano.2024.102753_bb0180","doi-asserted-by":"crossref","first-page":"6782","DOI":"10.1021\/la0104323","article-title":"Seeding growth for size control of 5\u221240\u00a0nm diameter gold nanoparticles","volume":"17","author":"Jana","year":"2001","journal-title":"Langmuir"},{"issue":"23","key":"10.1016\/j.nano.2024.102753_bb0185","doi-asserted-by":"crossref","first-page":"19142","DOI":"10.1021\/acssuschemeng.9b05128","article-title":"Controllable synthesis of calcium carbonate with different geometry: comprehensive analysis of particle formation, cellular uptake, and biocompatibility","volume":"7","author":"Bahrom","year":"2019","journal-title":"ACS Sustain Chem Eng"},{"issue":"8","key":"10.1016\/j.nano.2024.102753_bb0190","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.3390\/molecules23082021","article-title":"Sol-gel silica nanoparticles in medicine: a natural choice. Design, synthesis and products","volume":"23","author":"Gon\u00e7alves","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.nano.2024.102753_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2023.115325","article-title":"Synthesis of thieno [3,2-e] pyrrolo [1,2-a]pyrimidine derivatives and their precursors containing 2-aminothiophenes fragments as anticancer agents for therapy of pulmonary metastatic melanoma","volume":"254","author":"Rogova","year":"2023","journal-title":"Eur J Med Chem"},{"issue":"3","key":"10.1016\/j.nano.2024.102753_bb0200","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0168-3659(02)00211-0","article-title":"Lipophilic drug loaded nanospheres prepared by nanoprecipitation: effect of formulation variables on size, drug recovery and release kinetics","volume":"83","author":"Chorny","year":"2002","journal-title":"J Control Release"},{"issue":"36","key":"10.1016\/j.nano.2024.102753_bb0205","doi-asserted-by":"crossref","first-page":"18815","DOI":"10.1039\/D0NR05530A","article-title":"Green light-driven enhanced ammonia sensing at room temperature based on seed-mediated growth of gold-ferrosoferric oxide dumbbell-like heteronanostructures","volume":"12","author":"Yu","year":"2020","journal-title":"Nanoscale"},{"issue":"14","key":"10.1016\/j.nano.2024.102753_bb0210","doi-asserted-by":"crossref","first-page":"6593","DOI":"10.1021\/acs.chemmater.2c01507","article-title":"Universal chelator-free radiolabeling of organic and inorganic-based nanocarriers with diagnostic and therapeutic isotopes for internal radiotherapy","volume":"34","author":"Karpov","year":"2022","journal-title":"Chem Mater"},{"issue":"7","key":"10.1016\/j.nano.2024.102753_bb0215","doi-asserted-by":"crossref","first-page":"6458","DOI":"10.1021\/acsnano.8b02881","article-title":"Quantitative assessment of nanoparticle biodistribution by fluorescence imaging, revisited","volume":"12","author":"Meng","year":"2018","journal-title":"ACS Nano"},{"issue":"4","key":"10.1016\/j.nano.2024.102753_bb0220","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1039\/C7NR07495F","article-title":"Turning double hydrophilic into amphiphilic: IR825-conjugated polymeric nanomicelles for near-infrared fluorescence imaging-guided photothermal cancer therapy","volume":"10","author":"Pan","year":"2018","journal-title":"Nanoscale"},{"issue":"23","key":"10.1016\/j.nano.2024.102753_bb0225","doi-asserted-by":"crossref","first-page":"7984","DOI":"10.1039\/D1BM01398J","article-title":"Passive targeting of high-grade gliomas via the EPR effect: a closed path for metallic nanoparticles?","volume":"9","author":"Caro","year":"2021","journal-title":"Biomater Sci"},{"issue":"2","key":"10.1016\/j.nano.2024.102753_bb0230","doi-asserted-by":"crossref","first-page":"567","DOI":"10.7150\/thno.36777","article-title":"Delivery of polymeric nanostars for molecular imaging and endoradiotherapy through the enhanced permeability and retention (EPR) effect","volume":"10","author":"Goos","year":"2020","journal-title":"Theranostics"}],"container-title":["Nanomedicine: Nanotechnology, Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1549963424000224?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1549963424000224?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T07:21:43Z","timestamp":1718608903000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1549963424000224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":46,"alternative-id":["S1549963424000224"],"URL":"https:\/\/doi.org\/10.1016\/j.nano.2024.102753","relation":{},"ISSN":["1549-9634"],"issn-type":[{"value":"1549-9634","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of passive targeted delivery of inorganic and organic nanocarriers among different types of tumors","name":"articletitle","label":"Article Title"},{"value":"Nanomedicine: Nanotechnology, Biology and Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nano.2024.102753","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102753"}}