{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T22:32:42Z","timestamp":1772145162775,"version":"3.50.1"},"reference-count":63,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2006,2,1]],"date-time":"2006-02-01T00:00:00Z","timestamp":1138752000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2006,2]]},"DOI":"10.1016\/j.nbd.2005.07.015","type":"journal-article","created":{"date-parts":[[2005,9,7]],"date-time":"2005-09-07T19:58:28Z","timestamp":1126123108000},"page":"358-371","source":"Crossref","is-referenced-by-count":81,"title":["TAT-mediated delivery of Bcl-xL protein is neuroprotective against neonatal hypoxic\u2013ischemic brain injury via inhibition of caspases and AIF"],"prefix":"10.1016","volume":"21","author":[{"given":"Wei","family":"Yin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guodong","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Johnnides","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando P.","family":"Signore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumin","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert W.","family":"Hickey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2005.07.015_bib1","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1203\/00006450-200111000-00010","article-title":"Combination effect of systemic hypothermia and caspase inhibitor administration against hypoxic\u2013ischemic brain damage in neonatal rats","volume":"50","author":"Adachi","year":"2001","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.nbd.2005.07.015_bib2","doi-asserted-by":"crossref","first-page":"17107","DOI":"10.1073\/pnas.262460299","article-title":"Protection against ischemic brain injury by protein therapeutics","volume":"99","author":"Asoh","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2005.07.015_bib3","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1097\/00004647-199908000-00001","article-title":"Inflammatory mediators and stroke: new opportunities for novel therapeutics","volume":"19","author":"Barone","year":"1999","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2005.07.015_bib4","doi-asserted-by":"crossref","first-page":"5423","DOI":"10.1523\/JNEUROSCI.22-13-05423.2002","article-title":"In vivo delivery of a Bcl-xL fusion protein containing the TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis","volume":"22","author":"Cao","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2005.07.015_bib5","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1046\/j.1471-4159.1997.69010232.x","article-title":"Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death","volume":"69","author":"Chen","year":"1997","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2005.07.015_bib6","doi-asserted-by":"crossref","first-page":"4914","DOI":"10.1523\/JNEUROSCI.18-13-04914.1998","article-title":"Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia","volume":"18","author":"Chen","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2005.07.015_bib7","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1002\/ana.410410416","article-title":"Marked age-dependent neuroprotection by brain-derived neurotrophic factor against neonatal hypoxic\u2013ischemic brain injury","volume":"41","author":"Cheng","year":"1997","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2005.07.015_bib8","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1046\/j.1471-4159.2003.01657.x","article-title":"Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF","volume":"85","author":"Cohen","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2005.07.015_bib9","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1096\/fasebj.14.5.729","article-title":"Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis","volume":"14","author":"Daugas","year":"2000","journal-title":"FASEB J."},{"key":"10.1016\/j.nbd.2005.07.015_bib10","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1750-3639.2000.tb00247.x","article-title":"Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia","volume":"10","author":"Del Zoppo","year":"2000","journal-title":"Brain Pathol."},{"key":"10.1016\/j.nbd.2005.07.015_bib17","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/S0165-6147(03)00074-9","article-title":"Protein transduction technology offers novel therapeutic approach for brain ischemia","volume":"24","author":"Denicourt","year":"2003","journal-title":"Trends Parmacol. Sci."},{"key":"10.1016\/j.nbd.2005.07.015_bib11","doi-asserted-by":"crossref","first-page":"18188","DOI":"10.1074\/jbc.271.30.18188","article-title":"Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent","volume":"271","author":"Derossi","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2005.07.015_bib12","doi-asserted-by":"crossref","first-page":"12866","DOI":"10.1128\/JVI.76.24.12866-12876.2002","article-title":"Endocytosis is a critical step in entry of subgroup B avian leukosis viruses","volume":"76","author":"Diaz-Griffero","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.nbd.2005.07.015_bib13","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1182\/blood.V96.3.1030","article-title":"Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: reversibility at low apoptotic insult","volume":"96","author":"Dumont","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.nbd.2005.07.015_bib14","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1750-3639.2000.tb00239.x","article-title":"Fas\/CD95\/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic\u2013ischemic injury to the developing rat brain","volume":"10","author":"Felderhoff-Mueser","year":"2000","journal-title":"Brain Pathol."},{"key":"10.1016\/j.nbd.2005.07.015_bib15","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0304-3940(03)00466-X","article-title":"Desmethyl tirilazad improves neurologic function after hypoxic ischemic brain injury in piglets","volume":"344","author":"Feng","year":"2003","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2005.07.015_bib16","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s004010050753","article-title":"Bcl-2, Bax and Bcl-x expression following hypoxia\u2013ischemia in the infant rat brain","volume":"94","author":"Ferrer","year":"1997","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2005.07.015_bib18","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/0169-328X(96)00059-9","article-title":"Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats","volume":"40","author":"Gillardon","year":"1996","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.nbd.2005.07.015_bib19","doi-asserted-by":"crossref","first-page":"4304","DOI":"10.1073\/pnas.92.10.4304","article-title":"bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death","volume":"92","author":"Gonzalez-Garcia","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2005.07.015_bib20","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1074\/jbc.274.2.1156","article-title":"Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1\/Fas death","volume":"274","author":"Gross","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2005.07.015_bib21","doi-asserted-by":"crossref","first-page":"8999","DOI":"10.1021\/bi020715+","article-title":"Structural and dynamic properties of the HIV-1 tat transduction domain in the free and heparin-bound states","volume":"42","author":"Hakansson","year":"2003","journal-title":"Biochemistry"},{"key":"10.1016\/j.nbd.2005.07.015_bib22","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/00019052-200304000-00005","article-title":"The injury response in the term newborn brain: can we neuroprotect?","volume":"16","author":"Hamrick","year":"2003","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.nbd.2005.07.015_bib23","doi-asserted-by":"crossref","first-page":"30128","DOI":"10.1074\/jbc.M202931200","article-title":"Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic\u2013ischemic brain injury","volume":"277","author":"Han","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2005.07.015_bib24","first-page":"1550","article-title":"Involvement of caspase-3 in cell death after hypoxia\u2013ischemia declines during brain maturation","volume":"20","author":"He","year":"2000","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2005.07.015_bib25","doi-asserted-by":"crossref","first-page":"4386","DOI":"10.1073\/pnas.95.8.4386","article-title":"Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation","volume":"95","author":"Hu","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2005.07.015_bib26","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1750-3639.1998.tb00134.x","article-title":"Differential regulation of Bax, Bcl-2, and Bcl-X proteins in focal cortical ischemia in the rat","volume":"8","author":"Isenmann","year":"1998","journal-title":"Brain Pathol."},{"key":"10.1016\/j.nbd.2005.07.015_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2174\/1573396052953471","article-title":"Causal mechanisms underlying periventricular leukomalacia and cerebral palsy","volume":"1","author":"Kadhim","year":"2005","journal-title":"Curr. Pediatr. Rev."},{"key":"10.1016\/j.nbd.2005.07.015_bib28","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1097\/01.WCB.0000145666.68576.71","article-title":"Inhibition of toll-like receptor and cytokine signaling\u2014A unifying theme in ischemic tolerance","volume":"24","author":"Kariko","year":"2004","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2005.07.015_bib29","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1002\/ana.10356","article-title":"Intravenous TAT\u2013Bcl-Xl is protective after middle cerebral artery occlusion in mice","volume":"52","author":"Kilic","year":"2002","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2005.07.015_bib30","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1161\/01.STR.0000066869.45310.50","article-title":"Intravenous TAT\u2013GDNF is protective after focal cerebral ischemia in mice","volume":"34","author":"Kilic","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2005.07.015_bib31","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S1016-8478(23)13141-4","article-title":"Transduced TAT\u2013SOD fusion protein protects against ischemic brain injury","volume":"19","author":"Kim","year":"2005","journal-title":"Mol. Cells"},{"key":"10.1016\/j.nbd.2005.07.015_bib32","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1126\/science.275.5303.1132","article-title":"The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis","volume":"275","author":"Kluck","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.nbd.2005.07.015_bib33","first-page":"1","article-title":"Anoxic\u2013ischemic encephalopathy in rats","volume":"36","author":"Levine","year":"1960","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.nbd.2005.07.015_bib34","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0092-8674(00)81590-1","article-title":"Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis","volume":"94","author":"Li","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2005.07.015_bib35","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0301-0082(03)00005-4","article-title":"To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways","volume":"69","author":"Liou","year":"2003","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.nbd.2005.07.015_bib36","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1002\/j.1460-2075.1991.tb07697.x","article-title":"Endocytosis and targeting of exogenous HIV-1 Tat protein","volume":"10","author":"Mann","year":"1991","journal-title":"EMBO J."},{"key":"10.1016\/j.nbd.2005.07.015_bib37","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1126\/science.7878471","article-title":"Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice","volume":"267","author":"Motoyama","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.nbd.2005.07.015_bib38","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1038\/4042","article-title":"Transduction of full-length TAT fusion proteins into mammalian cells: TAT\u2013p27Kip1 induces cell migration","volume":"4","author":"Nagahara","year":"1998","journal-title":"Nat. Med."},{"key":"10.1016\/j.nbd.2005.07.015_bib39","doi-asserted-by":"crossref","first-page":"2987","DOI":"10.1523\/JNEUROSCI.19-08-02987.1999","article-title":"Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures","volume":"19","author":"Nagayama","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2005.07.015_bib40","doi-asserted-by":"crossref","first-page":"7994","DOI":"10.1523\/JNEUROSCI.20-21-07994.2000","article-title":"Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat","volume":"20","author":"Nakajima","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2005.07.015_bib41","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1523\/JNEUROSCI.21-06-01931.2001","article-title":"Delayed neurodegeneration in neonatal rat thalamus after hypoxia\u2013ischemia is apoptosis","volume":"21","author":"Northington","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2005.07.015_bib42","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1159\/000046141","article-title":"Neurodegeneration in the thalamus following neonatal hypoxia\u2013ischemia is programmed cell death","volume":"23","author":"Northington","year":"2001","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.nbd.2005.07.015_bib43","doi-asserted-by":"crossref","first-page":"5841","DOI":"10.1074\/jbc.273.10.5841","article-title":"Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex","volume":"273","author":"Pan","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2005.07.015_bib44","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1523\/JNEUROSCI.18-03-01009.1998","article-title":"Bcl-xL is an antiapoptotic regulator for postnatal CNS neurons","volume":"18","author":"Parsadanian","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2005.07.015_bib45","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0165-3806(00)00111-5","article-title":"Impairment of mitochondrial respiration after cerebral hypoxia\u2013ischemia in immature rats: relationship to activation of caspase-3 and neuronal injury","volume":"125","author":"Puka-Sundvall","year":"2000","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.nbd.2005.07.015_bib46","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.1161\/01.STR.29.12.2622","article-title":"Apoptosis in a neonatal rat model of cerebral hypoxia\u2013ischemia","volume":"29","author":"Pulera","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2005.07.015_bib47","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic\u2013ischemic brain damage in the rat","volume":"9","author":"Rice","year":"1981","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2005.07.015_bib48","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1074\/jbc.M209548200","article-title":"Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake","volume":"278","author":"Richard","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2005.07.015_bib49","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1159\/000047096","article-title":"Inflammatory mediators and neonatal brain damage","volume":"79","author":"Saliba","year":"2001","journal-title":"Bio. Neonate"},{"key":"10.1016\/j.nbd.2005.07.015_bib50","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1046\/j.1440-1681.1999.02987.x","article-title":"Barrier mechanisms in the brain: II. Immature brain","volume":"26","author":"Saunders","year":"1999","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.nbd.2005.07.015_bib51","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0006-8993(97)00173-X","article-title":"Methamphetamine exposure can produce neuronal degeneration in mouse hippocampal remnants","volume":"759","author":"Schmued","year":"1997","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2005.07.015_bib52","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1126\/science.285.5433.1569","article-title":"In vivo protein transduction: delivery of a biologically active protein into the mouse","volume":"285","author":"Schwarze","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.nbd.2005.07.015_bib53","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1006\/excr.1999.4751","article-title":"Adenovirus-mediated transfer of Bcl-X(L) protects neuronal cells from Bax-induced apoptosis","volume":"254","author":"Shinoura","year":"2000","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.nbd.2005.07.015_bib54","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/17135","article-title":"Molecular characterization of mitochondrial apoptosis-inducing factor","volume":"397","author":"Susin","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2005.07.015_bib55","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1203\/00006450-199004000-00001","article-title":"Experimental biology of cerebral hypoxia\u2013ischemia: relation to perinatal brain damage","volume":"27","author":"Vannucci","year":"1990","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.nbd.2005.07.015_bib56","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1053\/siny.2001.0041","article-title":"Molecular and biochemical mechanisms of perinatal brain injury","volume":"6","author":"Vexler","year":"2001","journal-title":"Semin. Neonatol."},{"key":"10.1016\/j.nbd.2005.07.015_bib57","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/jmr.636","article-title":"Cellular uptake of the Tat peptide: an endocytosis mechanism following ionic interactions","volume":"16","author":"Vives","year":"2003","journal-title":"J. Mol. Recognit."},{"key":"10.1016\/j.nbd.2005.07.015_bib58","doi-asserted-by":"crossref","first-page":"13003","DOI":"10.1073\/pnas.97.24.13003","article-title":"The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters","volume":"97","author":"Wender","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2005.07.015_bib59","first-page":"920","article-title":"The effect of age on susceptibility to hypoxic\u2013ischemic brain damage","volume":"51","author":"Yager","year":"1997","journal-title":"Kidney Int."},{"key":"10.1016\/j.nbd.2005.07.015_bib60","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1126\/science.275.5303.1129","article-title":"Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked","volume":"275","author":"Yang","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.nbd.2005.07.015_bib61","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1126\/science.1072221","article-title":"Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor","volume":"297","author":"Yu","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.nbd.2005.07.015_bib62","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1046\/j.1471-4159.2002.00975.x","article-title":"Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite","volume":"82","author":"Zhang","year":"2002","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2005.07.015_bib63","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1046\/j.1471-4159.2003.01832.x","article-title":"Involvement of apoptosis-inducing factor in neuronal death after hypoxia\u2013ischemia in the neonatal rat brain","volume":"86","author":"Zhu","year":"2003","journal-title":"J. Neurochem."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996105002147?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996105002147?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T14:15:04Z","timestamp":1706537704000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996105002147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2]]},"references-count":63,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["S0969996105002147"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2005.07.015","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2006,2]]}}}