{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:09:47Z","timestamp":1760954987598},"reference-count":45,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.nbd.2007.07.005","type":"journal-article","created":{"date-parts":[[2007,7,11]],"date-time":"2007-07-11T11:27:44Z","timestamp":1184153264000},"page":"175-183","source":"Crossref","is-referenced-by-count":20,"title":["Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis"],"prefix":"10.1016","volume":"28","author":[{"given":"Caroline L.","family":"Bellac","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roney S.","family":"Coimbra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franziska","family":"Simon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"Imboden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen L.","family":"Leib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2007.07.005_bib1","first-page":"5272","article-title":"Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family","volume":"57","author":"Akahani","year":"1997","journal-title":"Cancer Res."},{"key":"10.1016\/j.nbd.2007.07.005_bib2","first-page":"49","article-title":"Molecular mechanisms of brain damage in bacterial meningitis","volume":"14","author":"Braun","year":"1999","journal-title":"Adv. Pediatr. Infect. Dis."},{"key":"10.1016\/j.nbd.2007.07.005_bib3","first-page":"497","article-title":"Roles of galectin-3 in immune responses","volume":"53","author":"Chen","year":"2005","journal-title":"Arch. Immunol. Ther. Exp. (Warsz)"},{"key":"10.1016\/j.nbd.2007.07.005_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1741-7007-4-15","article-title":"Gene expression in cortex and hippocampus during acute pneumococcal meningitis","volume":"4","author":"Coimbra","year":"2006","journal-title":"BMC Biol."},{"key":"10.1016\/j.nbd.2007.07.005_bib5","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/j.micinf.2003.09.008","article-title":"Neutrophil granules and secretory vesicles in inflammation","volume":"5","author":"Faurschou","year":"2003","journal-title":"Microbes Infect."},{"key":"10.1016\/j.nbd.2007.07.005_bib6","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1750-3639.2001.tb00410.x","article-title":"Expression of death-related proteins in dentate granule cells in human bacterial meningitis","volume":"11","author":"Gerber","year":"2001","journal-title":"Brain Pathol."},{"key":"10.1016\/j.nbd.2007.07.005_bib7","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/01.mop.0000193292.09894.b7","article-title":"Strategies to prevent neuronal damage in paediatric bacterial meningitis","volume":"18","author":"Grandgirard","year":"2006","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1016\/j.nbd.2007.07.005_bib8","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1023\/B:GLYC.0000014090.63206.2f","article-title":"Galectin-9 in physiological and pathological conditions","volume":"19","author":"Hirashima","year":"2004","journal-title":"Glycoconjugate J."},{"key":"10.1016\/j.nbd.2007.07.005_bib9","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1189\/jlb.72.3.486","article-title":"Interferon-gamma stimulates the expression of galectin-9 in cultured human endothelial cells","volume":"72","author":"Imaizumi","year":"2002","journal-title":"J. Leukocyte Biol."},{"key":"10.1016\/j.nbd.2007.07.005_bib10","doi-asserted-by":"crossref","first-page":"3430","DOI":"10.1182\/blood.V91.9.3430","article-title":"Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils","volume":"91","author":"Karlsson","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.nbd.2007.07.005_bib11","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.4049\/jimmunol.170.7.3631","article-title":"Galectin-9 induces apoptosis through the calcium\u2013calpain\u2013caspase-1 pathway","volume":"170","author":"Kashio","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.nbd.2007.07.005_bib12","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1212\/WNL.58.2.186","article-title":"Oxidative stress in bacterial meningitis in humans","volume":"58","author":"Kastenbauer","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.nbd.2007.07.005_bib13","doi-asserted-by":"crossref","first-page":"3148","DOI":"10.1128\/IAI.64.8.3148-3153.1996","article-title":"Neurotoxicity of glia activated by gram-positive bacterial products depends on nitric oxide production","volume":"64","author":"Kim","year":"1996","journal-title":"Infect. Immun."},{"key":"10.1016\/j.nbd.2007.07.005_bib14","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/S1473-3099(02)00450-4","article-title":"Pathogenesis and pathophysiology of pneumococcal meningitis","volume":"2","author":"Koedel","year":"2002","journal-title":"Lancet, Infect. Dis."},{"key":"10.1016\/j.nbd.2007.07.005_bib15","doi-asserted-by":"crossref","first-page":"3939","DOI":"10.4049\/jimmunol.156.10.3939","article-title":"Galectin-3 promotes adhesion of human neutrophils to laminin","volume":"156","author":"Kuwabara","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.nbd.2007.07.005_bib16","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1023\/B:GLYC.0000014072.34840.04","article-title":"Introduction to galectins","volume":"19","author":"Leffler","year":"2004","journal-title":"Glycoconjugate J."},{"key":"10.1016\/j.nbd.2007.07.005_bib17","doi-asserted-by":"crossref","first-page":"583","DOI":"10.4049\/jimmunol.177.1.583","article-title":"A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2\/MyD88 pathway in microglia","volume":"177","author":"Lehnardt","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.nbd.2007.07.005_bib19","first-page":"928","article-title":"Strategies for prevention of brain damage resulting from bacterial meningitis","volume":"130","author":"Leib","year":"2000","journal-title":"Schweiz. Med. Wochenschr."},{"key":"10.1016\/j.nbd.2007.07.005_bib20","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.1172\/JCI119084","article-title":"Reactive oxygen intermediates contribute to necrotic and apoptotic neuronal injury in an infant rat model of bacterial meningitis due to group B streptococci","volume":"98","author":"Leib","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2007.07.005_bib18","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1086\/514226","article-title":"Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis","volume":"177","author":"Leib","year":"1998","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.nbd.2007.07.005_bib21","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1128\/IAI.68.2.615-620.2000","article-title":"Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis","volume":"68","author":"Leib","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.nbd.2007.07.005_bib22","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1086\/313922","article-title":"Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood\u2013brain barrier damage and neurological sequelae","volume":"31","author":"Leppert","year":"2000","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.nbd.2007.07.005_bib23","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1002\/glia.20301","article-title":"Macrophage\/microglia activation factor expression is restricted to lesion-associated microglial cells after brain trauma","volume":"53","author":"Lunemann","year":"2006","journal-title":"Glia"},{"key":"10.1016\/j.nbd.2007.07.005_bib24","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1093\/brain\/awl192","article-title":"TGFbeta receptor II gene deletion in leucocytes prevents cerebral vasculitis in bacterial meningitis","volume":"129","author":"Malipiero","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2007.07.005_bib25","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0014-5793(00)01547-7","article-title":"Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis","volume":"473","author":"Matarrese","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1016\/j.nbd.2007.07.005_bib26","doi-asserted-by":"crossref","first-page":"16976","DOI":"10.1074\/jbc.273.27.16976","article-title":"Human ecalectin, a variant of human galectin-9, is a novel eosinophil chemoattractant produced by T lymphocytes","volume":"273","author":"Matsumoto","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2007.07.005_bib27","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/00001432-200206000-00007","article-title":"Current concepts in the pathogenesis of meningitis caused by Streptococcus pneumoniae","volume":"15","author":"Meli","year":"2002","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.nbd.2007.07.005_bib28","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0166-2236(00)02024-5","article-title":"Neuronal injury in bacterial meningitis: mechanisms and implications for therapy","volume":"25","author":"Nau","year":"2002","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2007.07.005_bib29","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1189\/jlb.1204702","article-title":"Galectin-3 interacts with naive and primed neutrophils, inducing innate immune responses","volume":"78","author":"Nieminen","year":"2005","journal-title":"J. Leukocyte Biol."},{"key":"10.1016\/j.nbd.2007.07.005_bib30","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s11908-996-0023-7","article-title":"Acute Meningitis","volume":"1","author":"Pfister","year":"1999","journal-title":"Curr. Infect. Dis. Rep."},{"key":"10.1016\/j.nbd.2007.07.005_bib31","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/nri1130","article-title":"Three or more routes for leukocyte migration into the central nervous system","volume":"3","author":"Ransohoff","year":"2003","journal-title":"Nat. Rev., Immunol."},{"key":"10.1016\/j.nbd.2007.07.005_bib32","first-page":"1053","article-title":"Ultrastructural localization of the CD68 macrophage-associated antigen in human blood neutrophils and monocytes","volume":"139","author":"Saito","year":"1991","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.nbd.2007.07.005_bib34","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.4049\/jimmunol.165.4.2156","article-title":"Human galectin-3 is a novel chemoattractant for monocytes and macrophages","volume":"165","author":"Sano","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.nbd.2007.07.005_bib33","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1172\/JCI200317592","article-title":"Critical role of galectin-3 in phagocytosis by macrophages","volume":"112","author":"Sano","year":"2003","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2007.07.005_bib35","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.4049\/jimmunol.168.4.1813","article-title":"Role of galectin-3 as an adhesion molecule for neutrophil extravasation during streptococcal pneumonia","volume":"168","author":"Sato","year":"2002","journal-title":"J. Immunol."},{"issue":"Suppl. 2","key":"10.1016\/j.nbd.2007.07.005_bib36","doi-asserted-by":"crossref","first-page":"S225","DOI":"10.1086\/344939","article-title":"Pathophysiology of bacterial meningitis: mechanism(s) of neuronal injury","volume":"186","author":"Scheld","year":"2002","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.nbd.2007.07.005_bib37","doi-asserted-by":"crossref","first-page":"6078","DOI":"10.1074\/jbc.272.9.6078","article-title":"Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin","volume":"272","author":"Wada","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2007.07.005_bib38","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1172\/JCI119429","article-title":"Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin","volume":"99","author":"Wada","year":"1997","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2007.07.005_bib39","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/1097-4547(20000815)61:4<430::AID-JNR9>3.0.CO;2-3","article-title":"Galectin-3 is upregulated in microglial cells in response to ischemic brain lesions, but not to facial nerve axotomy","volume":"61","author":"Walther","year":"2000","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.nbd.2007.07.005_bib40","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S1474-4422(05)70288-X","article-title":"Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series","volume":"5","author":"Weisfelt","year":"2006","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nbd.2007.07.005_bib41","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.4049\/jimmunol.154.7.3479","article-title":"A human lectin, galectin-3 (epsilon bp\/Mac-2), stimulates superoxide production by neutrophils","volume":"154","author":"Yamaoka","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/j.nbd.2007.07.005_bib42","doi-asserted-by":"crossref","first-page":"6737","DOI":"10.1073\/pnas.93.13.6737","article-title":"Expression of galectin-3 modulates T-cell growth and apoptosis","volume":"93","author":"Yang","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2007.07.005_bib43","doi-asserted-by":"crossref","first-page":"3755","DOI":"10.1097\/00001756-200112040-00030","article-title":"Interleukin-1beta stimulates galectin-9 expression in human astrocytes","volume":"12","author":"Yoshida","year":"2001","journal-title":"NeuroReport"},{"key":"10.1016\/j.nbd.2007.07.005_bib44","doi-asserted-by":"crossref","first-page":"6852","DOI":"10.1074\/jbc.M107668200","article-title":"Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest","volume":"277","author":"Yoshii","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2007.07.005_bib45","doi-asserted-by":"crossref","first-page":"15819","DOI":"10.1074\/jbc.M200154200","article-title":"Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation","volume":"277","author":"Yu","year":"2002","journal-title":"J. Biol. Chem."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996107001453?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996107001453?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T08:50:09Z","timestamp":1683967809000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996107001453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":45,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S0969996107001453"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2007.07.005","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}