{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:38:09Z","timestamp":1791189489271,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["GM007748-31"],"award-info":[{"award-number":["GM007748-31"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HD045561"],"award-info":[{"award-number":["HD045561"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS39995"],"award-info":[{"award-number":["NS39995"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.nbd.2010.06.010","type":"journal-article","created":{"date-parts":[[2010,6,29]],"date-time":"2010-06-29T04:24:07Z","timestamp":1277785447000},"page":"370-377","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":98,"title":["Macroautophagy is defective in mucolipin-1-deficient mouse neurons"],"prefix":"10.1016","volume":"40","author":[{"given":"Cyntia","family":"Curcio-Morelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florie A.","family":"Charles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew C.","family":"Micsenyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhuvarahamurthy","family":"Venugopal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marsha F.","family":"Browning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kostantin","family":"Dobrenis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Cotman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven U.","family":"Walkley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan A.","family":"Slaugenhaupt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2010.06.010_bb0005","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/79095","article-title":"Identification of the gene causing mucolipidosis type IV","volume":"26","author":"Bargal","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.nbd.2010.06.010_bb0010","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/S0002-9297(07)62941-3","article-title":"Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV","volume":"67","author":"Bassi","year":"2000","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.nbd.2010.06.010_bb0015","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0022-3476(74)80671-2","article-title":"Congenital corneal clouding with abnormal systemic storage bodies: a new variant of mucolipidosis","volume":"84","author":"Berman","year":"1974","journal-title":"J. Pediatr."},{"key":"10.1016\/j.nbd.2010.06.010_bb0020","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1083\/jcb.200507002","article-title":"p62\/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death","volume":"171","author":"Bjorkoy","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0025","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1002\/jnr.490350513","article-title":"Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination","volume":"35","author":"Brewer","year":"1993","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.nbd.2010.06.010_bb0030","doi-asserted-by":"crossref","first-page":"20483","DOI":"10.1074\/jbc.M602180200","article-title":"Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis","volume":"281","author":"Cao","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.06.010_bb0035","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1097\/nen.0b013e31812503b6","article-title":"Developmental analysis of CNS pathology in the lysosomal storage disease alpha-mannosidosis","volume":"66","author":"Crawley","year":"2007","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0040","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1212\/WNL.51.2.565","article-title":"Mucolipidosis type IV: characteristic MRI findings","volume":"51","author":"Frei","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.nbd.2010.06.010_bb0045","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1203\/00006450-199506000-00003","article-title":"Cultured skin fibroblasts derived from patients with mucolipidosis 4 are auto-fluorescent","volume":"37","author":"Goldin","year":"1995","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.nbd.2010.06.010_bb0050","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1002\/humu.20094","article-title":"Transfer of a mitochondrial DNA fragment to MCOLN1 causes an inherited case of mucolipidosis IV","volume":"24","author":"Goldin","year":"2004","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.nbd.2010.06.010_bb0055","doi-asserted-by":"crossref","first-page":"29776","DOI":"10.1074\/jbc.M603783200","article-title":"Enhancing macroautophagy protects against ischemia\/reperfusion injury in cardiac myocytes","volume":"281","author":"Hamacher-Brady","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.06.010_bb0060","doi-asserted-by":"crossref","first-page":"39041","DOI":"10.1074\/jbc.M607982200","article-title":"Mitochondrial aberrations in mucolipidosis type IV","volume":"22","author":"Jennings","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.06.010_bb0065","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.cell.2009.03.015","article-title":"Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling","volume":"137","author":"Jin","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2010.06.010_bb0070","doi-asserted-by":"crossref","first-page":"5720","DOI":"10.1093\/emboj\/19.21.5720","article-title":"LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing","volume":"19","author":"Kabeya","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.nbd.2010.06.010_bb0075","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1091\/mbc.e07-11-1155","article-title":"Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy","volume":"19","author":"Kaushik","year":"2008","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.nbd.2010.06.010_bb0080","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1111\/j.1440-1789.2008.00966.x","article-title":"Frontotemporal lobar degeneration with ubiquitinated tau-negative inclusions and additional alpha-synuclein pathology but also unusual cerebellar ubiquitinated p62-positive, TDP-43-negative inclusions","volume":"29","author":"King","year":"2009","journal-title":"Neuropathology"},{"key":"10.1016\/j.nbd.2010.06.010_bb0085","doi-asserted-by":"crossref","first-page":"43218","DOI":"10.1074\/jbc.M508210200","article-title":"TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage","volume":"280","author":"Kiselyov","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.06.010_bb0090","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1113\/jphysiol.2006.119024","article-title":"TRPpathies","volume":"578","author":"Kiselyov","year":"2007","journal-title":"J. Physiol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0095","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4161\/auto.5338","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes","volume":"4","author":"Klionsky","year":"2008","journal-title":"Autophagy"},{"key":"10.1016\/j.nbd.2010.06.010_bb0100","doi-asserted-by":"crossref","first-page":"6898","DOI":"10.1523\/JNEUROSCI.20-18-06898.2000","article-title":"Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons","volume":"20","author":"Koike","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2010.06.010_bb0105","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1016\/S0002-9440(10)61253-9","article-title":"Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease)","volume":"167","author":"Koike","year":"2005","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0110","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/nature04723","article-title":"Loss of autophagy in the central nervous system causes neurodegeneration in mice","volume":"441","author":"Komatsu","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2010.06.010_bb0115","doi-asserted-by":"crossref","first-page":"862","DOI":"10.4161\/auto.8840","article-title":"A novel link between autophagy and the ubiquitin-proteasome system","volume":"5","author":"Korolchuk","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/j.nbd.2010.06.010_bb0120","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1097\/00001756-200107200-00009","article-title":"Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies","volume":"12","author":"Kuusisto","year":"2001","journal-title":"NeuroReport"},{"key":"10.1016\/j.nbd.2010.06.010_bb0125","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1093\/jnen\/62.12.1241","article-title":"Morphogenesis of Lewy bodies: dissimilar incorporation of alpha-synuclein, ubiquitin, and p62","volume":"62","author":"Kuusisto","year":"2003","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0130","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0014-5793(02)03670-0","article-title":"Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway","volume":"532","author":"LaPlante","year":"2002","journal-title":"FEBS Lett."},{"key":"10.1016\/j.nbd.2010.06.010_bb0135","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.ymgme.2006.05.016","article-title":"Lysosomal exocytosis is impaired in mucolipidosis type IV","volume":"89","author":"LaPlante","year":"2006","journal-title":"Mol. Genet. Metab."},{"key":"10.1016\/j.nbd.2010.06.010_bb0140","first-page":"897","article-title":"Autophagy in neurons: a review","volume":"17","author":"Larsen","year":"2002","journal-title":"Histol. Histopathol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0145","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/neu.10037","article-title":"Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death","volume":"51","author":"Lesuisse","year":"2002","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0150","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.febslet.2004.04.080","article-title":"Overexpression of wild-type and mutant mucolipin proteins in mammalian cells: effects on the late endocytic compartment organization","volume":"567","author":"Manzoni","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.nbd.2010.06.010_bb0155","doi-asserted-by":"crossref","first-page":"5805","DOI":"10.1073\/pnas.0507436103","article-title":"Consequences of the selective blockage of chaperone-mediated autophagy","volume":"103","author":"Massey","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2010.06.010_bb0160","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1097\/NEN.0b013e3181942cf0","article-title":"Neuropathology of the Mcoln1(\u2212\/\u2212) knockout mouse model of mucolipidosis type IV","volume":"68","author":"Micsenyi","year":"2009","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0165","doi-asserted-by":"crossref","first-page":"12751","DOI":"10.1074\/jbc.M511104200","article-title":"Posttranslational cleavage and adaptor protein complex-dependent trafficking of mucolipin-1","volume":"281","author":"Miedel","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.06.010_bb0170","doi-asserted-by":"crossref","first-page":"542","DOI":"10.4161\/auto.4600","article-title":"How to interpret LC3 immunoblotting","volume":"3","author":"Mizushima","year":"2007","journal-title":"Autophagy"},{"key":"10.1016\/j.nbd.2010.06.010_bb0175","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.bbadis.2008.10.002","article-title":"Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection","volume":"1782","author":"Nedelsky","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.nbd.2010.06.010_bb0180","doi-asserted-by":"crossref","first-page":"590","DOI":"10.4161\/auto.6259","article-title":"Neurodegenerative lysosomal disorders: a continuum from development to late age","volume":"4","author":"Nixon","year":"2008","journal-title":"Autophagy"},{"key":"10.1016\/j.nbd.2010.06.010_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.semcdb.2010.02.005","article-title":"Chaperone-mediated autophagy: Molecular mechanisms and physiological relevance","author":"Orenstein","year":"2010","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0190","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1093\/hmg\/ddm100","article-title":"Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects","volume":"16","author":"Pacheco","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2010.06.010_bb0195","doi-asserted-by":"crossref","first-page":"24131","DOI":"10.1074\/jbc.M702824200","article-title":"p62\/SQSTM1 binds directly to Atg8\/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy","volume":"282","author":"Pankiv","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.06.010_bb0200","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1111\/j.1600-0854.2006.00475.x","article-title":"Mucolipin-1 is a lysosomal membrane protein required for intracellular lactosylceramide traffic","volume":"7","author":"Pryor","year":"2006","journal-title":"Traffic"},{"key":"10.1016\/j.nbd.2010.06.010_bb0205","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4161\/auto.5.1.7293","article-title":"When more is less: excess and deficiency of autophagy coexist in skeletal muscle in Pompe disease","volume":"5","author":"Raben","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/j.nbd.2010.06.010_bb0210","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0076-6879(08)04021-4","article-title":"Monitoring autophagy in lysosomal storage disorders","volume":"453","author":"Raben","year":"2009","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0215","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1365-2990.2009.01034.x","article-title":"Review: autophagy in neurodegeneration: firefighter and\/or incendiarist?","volume":"35","author":"Rami","year":"2009","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0220","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s10735-006-9036-7","article-title":"Isolation of mouse neuritic mRNAs","volume":"37","author":"Reis","year":"2006","journal-title":"J. Mol. Histol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0225","doi-asserted-by":"crossref","first-page":"585","DOI":"10.4161\/auto.5.5.8823","article-title":"In search of an \u201cautophagomometer\u201d","volume":"5","author":"Rubinsztein","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/j.nbd.2010.06.010_bb0230","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/hmg\/ddm289","article-title":"A block of autophagy in lysosomal storage disorders","volume":"17","author":"Settembre","year":"2008","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2010.06.010_bb0235","doi-asserted-by":"crossref","first-page":"113","DOI":"10.4161\/auto.5227","article-title":"Lysosomal storage diseases as disorders of autophagy","volume":"4","author":"Settembre","year":"2008","journal-title":"Autophagy"},{"key":"10.1016\/j.nbd.2010.06.010_bb0240","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1093\/hmg\/9.17.2471","article-title":"Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel","volume":"9","author":"Sun","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2010.06.010_bb0245","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1523\/JNEUROSCI.22-01-00133.2002","article-title":"Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau","volume":"22","author":"Tanemura","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2010.06.010_bb0250","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/978-1-59745-157-4_4","article-title":"LC3 and Autophagy","volume":"445","author":"Tanida","year":"2008","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0255","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1471-2121-8-54","article-title":"Lysosomal trafficking functions of mucolipin-1 in murine macrophages","volume":"8","author":"Thompson","year":"2007","journal-title":"BMC Cell Biol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0260","doi-asserted-by":"crossref","first-page":"17517","DOI":"10.1074\/jbc.M600807200","article-title":"Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1","volume":"281","author":"Venkatachalam","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.06.010_bb0265","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.cell.2008.09.041","article-title":"Motor deficit in a Drosophila model of mucolipidosis type IV due to defective clearance of apoptotic cells","volume":"135","author":"Venkatachalam","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2010.06.010_bb0270","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s11910-007-0068-5","article-title":"Autophagy and neurodegeneration","volume":"7","author":"Ventruti","year":"2007","journal-title":"Curr. Neurol. Neurosci. Rep."},{"key":"10.1016\/j.nbd.2010.06.010_bb0275","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1086\/521954","article-title":"Neurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IV","volume":"81","author":"Venugopal","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.nbd.2010.06.010_bb0280","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/jcp.21676","article-title":"Chaperone-mediated autophagy is defective in mucolipidosis type IV","volume":"219","author":"Venugopal","year":"2009","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.nbd.2010.06.010_bb0285","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1600-0854.2006.00387.x","article-title":"Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes","volume":"7","author":"Vergarajauregui","year":"2006","journal-title":"Traffic"},{"key":"10.1016\/j.nbd.2010.06.010_bb0290","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1093\/hmg\/ddn174","article-title":"Autophagic dysfunction in mucolipidosis type IV patients","volume":"17","author":"Vergarajauregui","year":"2008","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2010.06.010_bb0295","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1089\/109065701753145529","article-title":"Rapid detection of the two common mutations in Ashkenazi Jewish patients with mucolipidosis type IV","volume":"5","author":"Wang","year":"2002","journal-title":"Genet Test."},{"key":"10.1016\/j.nbd.2010.06.010_bb0300","first-page":"62079","article-title":"Signaling, polyubiquitination, trafficking, and inclusions: sequestosome 1\/p62's role in neurodegenerative disease","author":"Wooten","year":"2006","journal-title":"J. Biomed. Biotechnol."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996110002068?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996110002068?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:05:19Z","timestamp":1760850319000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996110002068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":60,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0969996110002068"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2010.06.010","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Macroautophagy is defective in mucolipin-1-deficient mouse neurons","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2010.06.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}