{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:42:37Z","timestamp":1760852557896,"version":"build-2065373602"},"reference-count":68,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.nbd.2010.08.013","type":"journal-article","created":{"date-parts":[[2010,8,21]],"date-time":"2010-08-21T05:32:28Z","timestamp":1282368748000},"page":"11-22","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Human cytomegalovirus UL97 kinase prevents the deposition of mutant protein aggregates in cellular models of Huntington's disease and Ataxia"],"prefix":"10.1016","volume":"41","author":[{"given":"Cristy","family":"Tower","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lianwu","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Gill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Prichard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu","family":"Lesort","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Sztul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2010.08.013_bb0005","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1128\/MCB.18.2.1084","article-title":"The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein","volume":"18","author":"Alcalay","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0010","doi-asserted-by":"crossref","first-page":"11338","DOI":"10.1021\/bi020314u","article-title":"Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes","volume":"41","author":"Anguiano","year":"2002","journal-title":"Biochemistry"},{"key":"10.1016\/j.nbd.2010.08.013_bb0015","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/nature02998","article-title":"Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death","volume":"431","author":"Arrasate","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2010.08.013_bb0020","doi-asserted-by":"crossref","first-page":"11943","DOI":"10.1128\/JVI.76.23.11943-11952.2002","article-title":"Relationship between autophosphorylation and phosphorylation of exogenous substrates by the human cytomegalovirus UL97 protein kinase","volume":"76","author":"Baek","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0025","doi-asserted-by":"crossref","first-page":"29593","DOI":"10.1074\/jbc.M202312200","article-title":"Specific phosphorylation of exogenous protein and peptide substrates by the human cytomegalovirus UL97 protein kinase. Importance of the P+5 position","volume":"277","author":"Baek","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.08.013_bb0030","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.virol.2004.03.015","article-title":"Phosphorylation of the RNA polymerase II carboxyl-terminal domain in human cytomegalovirus-infected cells and in vitro by the viral UL97 protein kinase","volume":"324","author":"Baek","year":"2004","journal-title":"Virology"},{"key":"10.1016\/j.nbd.2010.08.013_bb0035","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1038\/nrm2277","article-title":"Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies","volume":"8","author":"Bernardi","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0040","doi-asserted-by":"crossref","first-page":"3810","DOI":"10.1128\/JVI.76.8.3810-3818.2002","article-title":"Effects of promyelocytic leukemia protein on virus-host balance","volume":"76","author":"Bonilla","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0045","doi-asserted-by":"crossref","first-page":"4330","DOI":"10.1073\/pnas.0407252102","article-title":"The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formation","volume":"102","author":"Burnett","year":"2005","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2010.08.013_bb0050","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.1093\/hmg\/ddg344","article-title":"The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity","volume":"12","author":"Burnett","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2010.08.013_bb0055","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1093\/hmg\/9.19.2811","article-title":"Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila","volume":"9","author":"Chan","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2010.08.013_bb0060","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1006\/jmbi.2001.4850","article-title":"Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity","volume":"311","author":"Chen","year":"2001","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0065","doi-asserted-by":"crossref","first-page":"7391","DOI":"10.1021\/bi011772q","article-title":"Amyloid-like features of polyglutamine aggregates and their assembly kinetics","volume":"41","author":"Chen","year":"2002","journal-title":"Biochemistry"},{"key":"10.1016\/j.nbd.2010.08.013_bb0070","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1038\/nm1197-1233","article-title":"Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1\/CIP1 via C\/EBPbeta","volume":"3","author":"Chinery","year":"1997","journal-title":"Nat. Med."},{"key":"10.1016\/j.nbd.2010.08.013_bb0075","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1006\/nbdi.2001.0390","article-title":"Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells","volume":"8","author":"Chun","year":"2001","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2010.08.013_bb0080","doi-asserted-by":"crossref","first-page":"2552","DOI":"10.1021\/bi991447r","article-title":"Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid","volume":"39","author":"Conway","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.nbd.2010.08.013_bb0085","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1146\/annurev.genom.1.1.281","article-title":"Trinucleotide repeats: mechanisms and pathophysiology","volume":"1","author":"Cummings","year":"2000","journal-title":"Annu. Rev. Genomics Hum. Genet."},{"key":"10.1016\/j.nbd.2010.08.013_bb0090","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1093\/hmg\/10.14.1511","article-title":"Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice","volume":"10","author":"Cummings","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2010.08.013_bb0095","doi-asserted-by":"crossref","first-page":"32046","DOI":"10.1074\/jbc.M201750200","article-title":"Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability","volume":"277","author":"Dahlgren","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.08.013_bb0100","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0092-8674(00)80513-9","article-title":"Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation","volume":"90","author":"Davies","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2010.08.013_bb0105","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S1097-2765(04)00062-0","article-title":"PML is a direct p53 target that modulates p53 effector functions","volume":"13","author":"de Stanchina","year":"2004","journal-title":"Mol. Cell"},{"key":"10.1016\/j.nbd.2010.08.013_bb0110","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1126\/science.277.5334.1990","article-title":"Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain","volume":"277","author":"DiFiglia","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.nbd.2010.08.013_bb0115","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1093\/hmg\/ddl210","article-title":"Green tea (\u2212)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models","volume":"15","author":"Ehrnhoefer","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2010.08.013_bb0120","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.nbd.2005.05.015","article-title":"Transcriptional repression and cell death induced by nuclear aggregates of non-polyglutamine protein","volume":"20","author":"Fu","year":"2005","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2010.08.013_bb0125","doi-asserted-by":"crossref","first-page":"4905","DOI":"10.1091\/mbc.e05-01-0019","article-title":"Nuclear aggresomes form by fusion of PML-associated aggregates","volume":"16","author":"Fu","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.nbd.2010.08.013_bb0130","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/ng0997-100","article-title":"The Werner syndrome protein is a DNA helicase","volume":"17","author":"Gray","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1016\/j.nbd.2010.08.013_bb0135","doi-asserted-by":"crossref","first-page":"35833","DOI":"10.1074\/jbc.M206280200","article-title":"The NH2-terminal domain of Golgin-160 contains both Golgi and nuclear targeting information","volume":"277","author":"Hicks","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.08.013_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ncb715","article-title":"Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2","volume":"4","author":"Hofmann","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0145","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/2410","article-title":"The premature ageing syndrome protein, WRN, is a 3\u2032\u2013>5\u2032 exonuclease","volume":"20","author":"Huang","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.nbd.2010.08.013_bb0150","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1126\/science.1152095","article-title":"Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function","volume":"320","author":"Hume","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.nbd.2010.08.013_bb0155","doi-asserted-by":"crossref","first-page":"4603","DOI":"10.1073\/pnas.97.9.4603","article-title":"Functional interaction between the Werner syndrome protein and DNA polymerase delta","volume":"97","author":"Kamath-Loeb","year":"2000","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2010.08.013_bb0160","doi-asserted-by":"crossref","first-page":"55499","DOI":"10.1074\/jbc.M407128200","article-title":"The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C","volume":"279","author":"Kamath-Loeb","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.08.013_bb0165","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1126\/science.1079469","article-title":"Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis","volume":"300","author":"Kayed","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.nbd.2010.08.013_bb0170","doi-asserted-by":"crossref","first-page":"46363","DOI":"10.1074\/jbc.C400260200","article-title":"Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases","volume":"279","author":"Kayed","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.08.013_bb0175","doi-asserted-by":"crossref","first-page":"4230","DOI":"10.1074\/jbc.M808591200","article-title":"Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer","volume":"284","author":"Kayed","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.08.013_bb0180","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1002\/1531-8249(199912)46:6<842::AID-ANA6>3.0.CO;2-O","article-title":"Huntington aggregates may not predict neuronal death in Huntington's disease","volume":"46","author":"Kuemmerle","year":"1999","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0185","doi-asserted-by":"crossref","first-page":"6887","DOI":"10.1073\/pnas.95.12.6887","article-title":"Nucleolar localization of the Werner syndrome protein in human cells","volume":"95","author":"Marciniak","year":"1998","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2010.08.013_bb0190","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1099\/0022-1317-82-6-1439","article-title":"Inhibitors of human cytomegalovirus replication drastically reduce the activity of the viral protein kinase pUL97","volume":"82","author":"Marschall","year":"2001","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0195","doi-asserted-by":"crossref","first-page":"33357","DOI":"10.1074\/jbc.M502672200","article-title":"Cellular p32 recruits cytomegalovirus kinase pUL97 to redistribute the nuclear lamina","volume":"280","author":"Marschall","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.08.013_bb0205","doi-asserted-by":"crossref","first-page":"15179","DOI":"10.1073\/pnas.261400698","article-title":"Histone deacetylase inhibitors reduce polyglutamine toxicity","volume":"98","author":"McCampbell","year":"2001","journal-title":"Proc. Natl Acad. Sci. USA"},{"issue":"Pt 9","key":"10.1016\/j.nbd.2010.08.013_bb0210","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1099\/0022-1317-79-9-2105","article-title":"Functional regions of the human cytomegalovirus protein pUL97 involved in nuclear localization and phosphorylation of ganciclovir and pUL97 itself","volume":"79","author":"Michel","year":"1998","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0215","doi-asserted-by":"crossref","first-page":"6867","DOI":"10.1074\/jbc.M010121200","article-title":"An essential cytoplasmic domain for the Golgi localization of coiled-coil proteins with a COOH-terminal membrane anchor","volume":"276","author":"Misumi","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.08.013_bb0220","doi-asserted-by":"crossref","first-page":"8731","DOI":"10.1038\/sj.onc.1207079","article-title":"Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression","volume":"22","author":"Moller","year":"2003","journal-title":"Oncogene"},{"key":"10.1016\/j.nbd.2010.08.013_bb0225","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/nrn1587","article-title":"Modulation of neurodegeneration by molecular chaperones","volume":"6","author":"Muchowski","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2010.08.013_bb0230","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.2741\/3380","article-title":"Expanding PML's functional repertoire through post-translational mechanisms","volume":"14","author":"Nichol","year":"2009","journal-title":"Front. Biosci."},{"key":"10.1016\/j.nbd.2010.08.013_bb0235","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1093\/carcin\/bgg034","article-title":"Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process","volume":"24","author":"Opresko","year":"2003","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.nbd.2010.08.013_bb0240","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1146\/annurev.neuro.29.051605.113042","article-title":"Trinucleotide repeat disorders","volume":"30","author":"Orr","year":"2007","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2010.08.013_bb0245","doi-asserted-by":"crossref","first-page":"8582","DOI":"10.1128\/JVI.00031-06","article-title":"Cross talk between PML and p53 during poliovirus infection: implications for antiviral defense","volume":"80","author":"Pampin","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0255","doi-asserted-by":"crossref","first-page":"41032","DOI":"10.1074\/jbc.M205809200","article-title":"Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization","volume":"277","author":"Poirier","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2010.08.013_bb0260","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/hmg\/ddi071","article-title":"A structure-based analysis of huntingtin mutant polyglutamine aggregation and toxicity: evidence for a compact beta-sheet structure","volume":"14","author":"Poirier","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2010.08.013_bb0265","doi-asserted-by":"crossref","first-page":"5663","DOI":"10.1128\/JVI.73.7.5663-5670.1999","article-title":"A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency","volume":"73","author":"Prichard","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0270","doi-asserted-by":"crossref","first-page":"15494","DOI":"10.1128\/JVI.79.24.15494-15502.2005","article-title":"Human cytomegalovirus UL97 kinase is required for the normal intranuclear distribution of pp 65 and virion morphogenesis","volume":"79","author":"Prichard","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0275","doi-asserted-by":"crossref","first-page":"5054","DOI":"10.1128\/JVI.02174-07","article-title":"Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes","volume":"82","author":"Prichard","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0280","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S0896-6273(02)00872-3","article-title":"Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders","volume":"35","author":"Ross","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2010.08.013_bb0285","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/nrm1742","article-title":"Opinion: what is the role of protein aggregation in neurodegeneration?","volume":"6","author":"Ross","year":"2005","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0290","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1098\/rstb.1999.0452","article-title":"Polyglutamine pathogenesis","volume":"354","author":"Ross","year":"1999","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.nbd.2010.08.013_bb0295","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1073\/pnas.0237018100","article-title":"Polyglutamine fibrillogenesis: the pathway unfolds","volume":"100","author":"Ross","year":"2003","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2010.08.013_bb0300","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/sj.cdd.4401820","article-title":"The PML-nuclear body associated protein Daxx regulates the cellular response to CD40","volume":"13","author":"Salomoni","year":"2006","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.nbd.2010.08.013_bb0305","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/nature01301","article-title":"Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders","volume":"421","author":"Sanchez","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2010.08.013_bb0310","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0092-8674(00)81782-1","article-title":"Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions","volume":"95","author":"Saudou","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2010.08.013_bb0315","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.molcel.2006.09.013","article-title":"The mechanisms of PML-nuclear body formation","volume":"24","author":"Shen","year":"2006","journal-title":"Mol. Cell."},{"key":"10.1016\/j.nbd.2010.08.013_bb0320","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0092-8674(00)81743-2","article-title":"Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial?","volume":"95","author":"Sisodia","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2010.08.013_bb0325","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.mad.2007.09.004","article-title":"Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML","volume":"128","author":"Vaitiekunaite","year":"2007","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.nbd.2010.08.013_bb0330","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/nsmb860","article-title":"Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer","volume":"11","author":"Wacker","year":"2004","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.nbd.2010.08.013_bb0335","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/70532","article-title":"Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70","volume":"23","author":"Warrick","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.nbd.2010.08.013_bb0340","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.molcel.2005.02.030","article-title":"Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism","volume":"18","author":"Warrick","year":"2005","journal-title":"Mol. Cell"},{"key":"10.1016\/j.nbd.2010.08.013_bb0345","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1021\/ar050069h","article-title":"Kinetics and thermodynamics of amyloid fibril assembly","volume":"39","author":"Wetzel","year":"2006","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.nbd.2010.08.013_bb0350","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1093\/hmg\/ddl164","article-title":"Ataxin-3 binds VCP\/p97 and regulates retrotranslocation of ERAD substrates","volume":"15","author":"Zhong","year":"2006","journal-title":"Hum. Mol. Genet."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096999611000272X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096999611000272X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:06:18Z","timestamp":1760850378000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S096999611000272X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":68,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["S096999611000272X"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2010.08.013","relation":{},"ISSN":["0969-9961"],"issn-type":[{"type":"print","value":"0969-9961"}],"subject":[],"published":{"date-parts":[[2011,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human cytomegalovirus UL97 kinase prevents the deposition of mutant protein aggregates in cellular models of Huntington's disease and Ataxia","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2010.08.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}