{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:05:53Z","timestamp":1790129153170,"version":"4.0.1"},"reference-count":44,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Michael J. Fox Foundation for Parkinson's Research, United States of America","award":["P14104"],"award-info":[{"award-number":["P14104"]}]},{"name":"Medical Research Council, United Kingdom"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.nbd.2011.05.009","type":"journal-article","created":{"date-parts":[[2011,5,24]],"date-time":"2011-05-24T22:21:21Z","timestamp":1306275681000},"page":"609-615","source":"Crossref","is-referenced-by-count":41,"title":["Serotonergic mediated body mass index changes in Parkinson's disease"],"prefix":"10.1016","volume":"43","author":[{"given":"Marios","family":"Politis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"Loane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kit","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Brooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Piccini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2011.05.009_bb0005","first-page":"879","article-title":"Diet, body size and micronutrient status in Parkinson's disease","volume":"46","author":"Abbott","year":"1992","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.nbd.2011.05.009_bb0010","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.neuroimage.2003.10.046","article-title":"A database of [(18)F]-altanserin binding to 5-HT(2A) receptors in normal volunteers: normative data and relationship to physiological and demographic variables","volume":"21","author":"Adams","year":"2004","journal-title":"NeuroImage"},{"key":"10.1016\/j.nbd.2011.05.009_bb0015","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1146\/annurev.ne.09.030186.002041","article-title":"Parallel organization of functionally segregated circuits linking basal ganglia and cortex","volume":"9","author":"Alexander","year":"1986","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2011.05.009_bb0020","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1093\/ajhp\/54.18.2059","article-title":"Dexfenfluramine hydrochloride: an anorexigenic agent","volume":"54","author":"Bever","year":"1997","journal-title":"Am. J. Health Syst. Pharm"},{"key":"10.1016\/j.nbd.2011.05.009_bb0025","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0002-8223(95)00269-3","article-title":"Weight change and body composition in patients with Parkinson's disease","volume":"95","author":"Beyer","year":"1995","journal-title":"J. Am. Diet. Assoc."},{"key":"10.1016\/j.nbd.2011.05.009_bb0030","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1038\/oby.2010.57","article-title":"Food-related odor probes of brain reward circuits during hunger: a pilot FMRI study","volume":"18","author":"Bragulat","year":"2010","journal-title":"Obesity"},{"key":"10.1016\/j.nbd.2011.05.009_bb0035","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1126\/science.130678","article-title":"Hyperphagia and obesity following serotonin depletion by intraventricular p-chlorophenylalanine","volume":"192","author":"Breisch","year":"1976","journal-title":"Science"},{"key":"10.1016\/j.nbd.2011.05.009_bb0040","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.bbrc.2003.11.150","article-title":"Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin","volume":"313","author":"Carlini","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.nbd.2011.05.009_bb0045","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S1474-4422(06)70373-8","article-title":"National Institute for Clinical Excellence. Non-motor symptoms of Parkinson's disease: diagnosis and management","volume":"5","author":"Chaudhuri","year":"2006","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nbd.2011.05.009_bb0050","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1002\/ana.10577","article-title":"Weight loss in Parkinson's disease","volume":"53","author":"Chen","year":"2003","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2011.05.009_bb0055","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/cne.901560205","article-title":"Connections of the median and dorsal raphe nuclei in the rat: an autoradiographic and degeneration study","volume":"156","author":"Conrad","year":"1974","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.nbd.2011.05.009_bb0060","doi-asserted-by":"crossref","first-page":"3086","DOI":"10.1523\/JNEUROSCI.0130-04.2004","article-title":"Representation in the human brain of food texture and oral fat","volume":"24","author":"De Araujo","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2011.05.009_bb0065","series-title":"The Human Brain: Surface, Blood Supply, and Three-dimensional Sectional Anatomy","author":"Duvernoy","year":"1999"},{"key":"10.1016\/j.nbd.2011.05.009_bb0070","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.neuroimage.2009.01.050","article-title":"Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use","volume":"46","author":"Erritzoe","year":"2009","journal-title":"NeuroImage"},{"key":"10.1016\/j.nbd.2011.05.009_bb0075","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.neuroimage.2010.03.086","article-title":"Cerebral serotonin transporter binding is inversely related to body mass index","volume":"52","author":"Erritzoe","year":"2010","journal-title":"NeuroImage"},{"key":"10.1016\/j.nbd.2011.05.009_bb0080","doi-asserted-by":"crossref","first-page":"617","DOI":"10.5694\/j.1326-5377.1975.tb106144.x","article-title":"Fattening of parkinsonians: a hypothalamic side effect of L-dopa?","volume":"2","author":"Gasparini","year":"1975","journal-title":"Med. J. Aust."},{"key":"10.1016\/j.nbd.2011.05.009_bb0085","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1097\/00004647-200111000-00010","article-title":"Positron emission tomography quantification of [(11)C]-DASB binding to the human serotonin transporter: modeling strategies","volume":"21","author":"Ginovart","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2011.05.009_bb0090","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1111\/j.1460-9568.2009.06949.x","article-title":"Fasting biases brain reward systems towards high-calorie foods","volume":"30","author":"Goldstone","year":"2009","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2011.05.009_bb0095","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.tins.2008.08.002","article-title":"Limbic and cortical information processing in the nucleus accumbens","volume":"31","author":"Goto","year":"2008","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2011.05.009_bb0100","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1093\/cercor\/bhp169","article-title":"How the brain represents the reward value of fat in the mouth","volume":"20","author":"Grabenhorst","year":"2010","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.nbd.2011.05.009_bb0105","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.pneurobio.2008.09.004","article-title":"The cognitive functions of the caudate nucleus","volume":"86","author":"Grahn","year":"2008","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.nbd.2011.05.009_bb0110","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.physbeh.2005.08.066","article-title":"Corticostriatal-hypothalamic circuitry and food motivation: integration of energy, action and reward","volume":"86","author":"Kelley","year":"2005","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.nbd.2011.05.009_bb0115","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.nucmedbio.2004.10.001","article-title":"Regional distribution of serotonin transporter protein in postmortem human brain: is the cerebellum a SERT-free brain region?","volume":"32","author":"Kish","year":"2005","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.nbd.2011.05.009_bb0120","first-page":"120","article-title":"Preferential loss of serotonin markers in caudate versus putamen in Parkinson's disease","volume":"131","author":"Kish","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2011.05.009_bb0125","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0006-3223(98)00186-3","article-title":"Hypothalamic serotonin in control of eating behavior, meal size, and body weight","volume":"44","author":"Leibowitz","year":"1998","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2011.05.009_bb0130","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.pnpbp.2005.03.012","article-title":"Pharmacogenetics of the serotonin transporter","volume":"29","author":"Lesch","year":"2005","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2011.05.009_bb0135","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1097\/00004647-199609000-00008","article-title":"Distribution volume ratios without blood sampling from graphical analysis of PET data","volume":"16","author":"Logan","year":"1996","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2011.05.009_bb0140","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/mds.10630","article-title":"Parkinson's disease patients with bilateral subthalamic deep brain stimulation gain weight","volume":"19","author":"Macia","year":"2004","journal-title":"Mov. Disord."},{"key":"10.1016\/j.nbd.2011.05.009_bb0145","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/oby.2009.220","article-title":"Neural mechanisms associated with food motivation in obese and healthy weight adults","volume":"18","author":"Martin","year":"2010","journal-title":"Obesity"},{"key":"10.1016\/j.nbd.2011.05.009_bb0150","doi-asserted-by":"crossref","first-page":"T161","DOI":"10.1016\/j.neuroimage.2008.04.128","article-title":"Inverse correlation between body mass index and serotonin transporter binding in human brain: a [11C-DASB] PET study","volume":"41","author":"Matsumoto","year":"2008","journal-title":"NeuroImage"},{"key":"10.1016\/j.nbd.2011.05.009_bb0155","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0006-3223(03)00530-4","article-title":"Prevalence, etiology, and treatment of depression in Parkinson's disease","volume":"54","author":"McDonald","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2011.05.009_bb0160","first-page":"1936","article-title":"Correction of head movement on PET studies: comparison of methods","volume":"47","author":"Montgomery","year":"2006","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.nbd.2011.05.009_bb0165","first-page":"65","article-title":"Body weight loss in patients with Parkinson's disease","volume":"41","author":"Moroo","year":"1994","journal-title":"Neurol. Med."},{"key":"10.1016\/j.nbd.2011.05.009_bb0170","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0169-328X(88)90013-7","article-title":"Regulation of striatal prodynorphin mRNA levels by the raphe-striatal pathway","volume":"464","author":"Morris","year":"1988","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2011.05.009_bb0175","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/nature05026","article-title":"Central nervous system control of food intake and body weight","volume":"443","author":"Morton","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2011.05.009_bb0180","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1034\/j.1600-0404.2000.101002079.x","article-title":"Weight gain following unilateral pallidotomy in Parkinson's disease","volume":"101","author":"Ondo","year":"2000","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.nbd.2011.05.009_bb0185","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.nbd.2010.05.028","article-title":"Staging of serotonergic dysfunction in Parkinson's disease: an in vivo 11C-DASB PET study","volume":"40","author":"Politis","year":"2010","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2011.05.009_bb0190","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1093\/cercor\/bhj088","article-title":"Basal ganglia functional connectivity based on a meta-analysis of 126 positron emission tomography and functional magnetic resonance imaging publications","volume":"16","author":"Postuma","year":"2006","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.nbd.2011.05.009_bb0195","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.neuroimage.2007.05.008","article-title":"Differential activation of the dorsal striatum by high-calorie visual food stimuli in obese individuals","volume":"37","author":"Rothemund","year":"2007","journal-title":"NeuroImage"},{"key":"10.1016\/j.nbd.2011.05.009_bb0200","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0028-3908(78)90056-4","article-title":"Gastrointestinal motility and body weight gain in rats after brain serotonin depletion by 5, 7-dihydroxytryptamine","volume":"17","author":"Saller","year":"1978","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.nbd.2011.05.009_bb0205","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0006-8993(83)90993-9","article-title":"Reduction of cortical dopamine, noradrenaline, serotonin and their metabolites in Parkinson's disease","volume":"275","author":"Scatton","year":"1983","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2011.05.009_bb0210","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/35007534","article-title":"Central nervous system control of food intake","volume":"404","author":"Schwartz","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2011.05.009_bb0215","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0006-8993(94)91761-2","article-title":"Noradrenaline, dopamine and serotonin levels and metabolism in the human hypothalamus: observations in Parkinson's disease and normal subjects","volume":"639","author":"Shannak","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2011.05.009_bb0220","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1176\/ajp.152.11.1668","article-title":"Acute tryptophan depletion and increased food intake and irritability in bulimia nervosa","volume":"152","author":"Weltzin","year":"1995","journal-title":"Am. J. Psychiatry"}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996111001653?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996111001653?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T14:18:16Z","timestamp":1592576296000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996111001653"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0969996111001653"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2011.05.009","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}