{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:52:10Z","timestamp":1791183130915,"version":"4.1.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"NIH","award":["R01 NS051590"],"award-info":[{"award-number":["R01 NS051590"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.nbd.2012.06.013","type":"journal-article","created":{"date-parts":[[2012,6,30]],"date-time":"2012-06-30T01:00:20Z","timestamp":1341018020000},"page":"115-123","source":"Crossref","is-referenced-by-count":43,"title":["The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop codon read-through"],"prefix":"10.1016","volume":"48","author":[{"given":"Xuan","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengnan","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciria C.","family":"Hernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ningning","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Macdonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2012.06.013_bb0005","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1523\/JNEUROSCI.13-04-01429.1993","article-title":"Assembly of GABAA receptor subunits: alpha 1 beta 1 and alpha 1 beta 1 gamma 2S subunits produce unique ion channels with dissimilar single-channel properties","volume":"13","author":"Angelotti","year":"1993","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2012.06.013_bb0010","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1523\/JNEUROSCI.13-04-01418.1993","article-title":"Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate\/marker gene technique","volume":"13","author":"Angelotti","year":"1993","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2012.06.013_bb0015","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ceb.2004.03.003","article-title":"Nonsense-mediated mRNA decay: terminating erroneous gene expression","volume":"16","author":"Baker","year":"2004","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0020","doi-asserted-by":"crossref","first-page":"46020","DOI":"10.1074\/jbc.M207663200","article-title":"Forced subunit assembly in alpha1beta2gamma2 GABAA receptors. Insight into the absolute arrangement","volume":"277","author":"Baumann","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2012.06.013_bb0025","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.molmed.2006.06.001","article-title":"Stop-codon read-through for patients affected by a lysosomal storage disorder","volume":"12","author":"Brooks","year":"2006","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.nbd.2012.06.013_bb0030","doi-asserted-by":"crossref","first-page":"3116","DOI":"10.1128\/MCB.20.9.3116-3124.2000","article-title":"Suppression of nonsense mutations in cell culture and mice by multimerized suppressor tRNA genes","volume":"20","author":"Buvoli","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0035","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1002\/ana.21440","article-title":"Developmental impact of a familial GABAA receptor epilepsy mutation","volume":"64","author":"Chiu","year":"2008","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0040","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1074\/jbc.271.1.89","article-title":"Assembly and cell surface expression of heteromeric and homomeric gamma-aminobutyric acid type A receptors","volume":"271","author":"Connolly","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2012.06.013_bb0045","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/dvg.20263","article-title":"Knock-in mice reveal nonsense-mediated mRNA decay in the brain","volume":"45","author":"Contet","year":"2007","journal-title":"Genesis"},{"key":"10.1016\/j.nbd.2012.06.013_bb0050","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1038\/12207","article-title":"Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues","volume":"2","author":"Crestani","year":"1999","journal-title":"Nat. Neurosci."},{"issue":"Suppl. 2","key":"10.1016\/j.nbd.2012.06.013_bb0055","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1469-8749.2011.03965.x","article-title":"Molecular genetics of Dravet syndrome","volume":"53","author":"De Jonghe","year":"2011","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0060","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1073\/pnas.0711795105","article-title":"PTC124 is an orally bioavailable compound that promotes suppression of the human CFTR-G542X nonsense allele in a CF mouse model","volume":"105","author":"Du","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2012.06.013_bb0065","doi-asserted-by":"crossref","first-page":"12293","DOI":"10.1074\/jbc.M312975200","article-title":"Lassa virus glycoprotein signal peptide displays a novel topology with an extended endoplasmic reticulum luminal region","volume":"279","author":"Eichler","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2012.06.013_bb0070","doi-asserted-by":"crossref","first-page":"10119","DOI":"10.1073\/pnas.0802753105","article-title":"Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway","volume":"105","author":"El Hage","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2012.06.013_bb0075","doi-asserted-by":"crossref","first-page":"37995","DOI":"10.1074\/jbc.M508305200","article-title":"Endoplasmic reticulum retention and associated degradation of a GABAA receptor epilepsy mutation that inserts an aspartate in the M3 transmembrane segment of the alpha1 subunit","volume":"280","author":"Gallagher","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2012.06.013_bb0080","series-title":"The Proteomics Protocols Handbook","first-page":"571","article-title":"Protein identification and analysis tools on the ExPASy server","author":"Gasteiger","year":"2005"},{"key":"10.1016\/j.nbd.2012.06.013_bb0085","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/nature04404","article-title":"GABA regulates synaptic integration of newly generated neurons in the adult brain","volume":"439","author":"Ge","year":"2006","journal-title":"Nature"},{"issue":"Pt 3","key":"10.1016\/j.nbd.2012.06.013_bb0090","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/j.1469-7793.1998.609bv.x","article-title":"Zn2+ inhibition of recombinant GABAA receptors: an allosteric, state-dependent mechanism determined by the gamma-subunit","volume":"506","author":"Gingrich","year":"1998","journal-title":"J. Physiol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0095","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1016\/S0140-6736(09)60819-9","article-title":"PTC124 for cystic fibrosis","volume":"373","author":"Goodier","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2012.06.013_bb0100","doi-asserted-by":"crossref","first-page":"7749","DOI":"10.1073\/pnas.92.17.7749","article-title":"Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors","volume":"92","author":"Gunther","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2012.06.013_bb0105","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1086\/338710","article-title":"Truncation of the GABA(A)-receptor gamma2 subunit in a family with generalized epilepsy with febrile seizures plus","volume":"70","author":"Harkin","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.nbd.2012.06.013_bb0110","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.tibs.2006.08.004","article-title":"The surprising complexity of signal sequences","volume":"31","author":"Hegde","year":"2006","journal-title":"Trends Biochem. Sci."},{"issue":"Pt 23","key":"10.1016\/j.nbd.2012.06.013_bb0115","doi-asserted-by":"crossref","first-page":"5857","DOI":"10.1113\/jphysiol.2011.218883","article-title":"The GABRA6 mutation, R46W, associated with childhood absence epilepsy alters {alpha}6{beta}2{gamma}2 and {alpha}6{beta}2{delta} GABAA receptor channel gating and expression","volume":"589","author":"Hernandez","year":"2011","journal-title":"J Physiol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0120","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/nm0496-467","article-title":"Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations","volume":"2","author":"Howard","year":"1996","journal-title":"Nat. Med."},{"issue":"Supplement 1","key":"10.1016\/j.nbd.2012.06.013_bb0125","article-title":"Possible pathogenesis of severe myoclonic epilepsy in infancy: a novel nonsense mutation of GABRG2 leading to aggregation of GABAA receptors in neurons","volume":"9","author":"Kanaumi","year":"2004","journal-title":"Neurol. Asia"},{"key":"10.1016\/j.nbd.2012.06.013_bb0140","doi-asserted-by":"crossref","first-page":"9438","DOI":"10.1021\/bi0342261","article-title":"Signal sequence cleavage and plasma membrane targeting of the retinal rod NCKX1 and cone NCKX2 Na+\/Ca2+\u2013K+ exchangers","volume":"42","author":"Kang","year":"2003","journal-title":"Biochemistry"},{"key":"10.1016\/j.nbd.2012.06.013_bb0130","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1523\/JNEUROSCI.4772-08.2009","article-title":"The GABRG2 mutation, Q351X, associated with generalized epilepsy with febrile seizures plus, has both loss of function and dominant-negative suppression","volume":"29","author":"Kang","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2012.06.013_bb0135","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.1523\/JNEUROSCI.4512-08.2009","article-title":"Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X","volume":"29","author":"Kang","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2012.06.013_bb0145","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/nature10165","article-title":"Converting nonsense codons into sense codons by targeted pseudouridylation","volume":"474","author":"Karijolich","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2012.06.013_bb0150","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1172\/JCI8055","article-title":"Correction of genetic disease by making sense from nonsense","volume":"104","author":"Kaufman","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2012.06.013_bb0155","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/sj.jid.5700031","article-title":"Aminoglycosides as potential pharmacogenetic agents in the treatment of Hailey\u2013Hailey disease","volume":"126","author":"Kellermayer","year":"2006","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0160","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/S0140-6736(08)61168-X","article-title":"Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial","volume":"372","author":"Kerem","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2012.06.013_bb0165","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1023\/A:1014238221426","article-title":"Suppression of nonsense mutations in the Dystrophin gene by a suppressor tRNA gene","volume":"36","author":"Kiselev","year":"2002","journal-title":"Mol. Biol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0170","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1111\/j.1471-4159.2005.03426.x","article-title":"Disruption of postsynaptic GABA receptor clusters leads to decreased GABAergic innervation of pyramidal neurons","volume":"95","author":"Li","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2012.06.013_bb0185","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.tig.2008.08.010","article-title":"Introducing sense into nonsense in treatments of human genetic diseases","volume":"24","author":"Linde","year":"2008","journal-title":"Trends Genet."},{"key":"10.1016\/j.nbd.2012.06.013_bb0175","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1038\/sj.ejhg.5201889","article-title":"The efficiency of nonsense-mediated mRNA decay is an inherent character and varies among different cells","volume":"15","author":"Linde","year":"2007","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.nbd.2012.06.013_bb0180","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1172\/JCI28523","article-title":"Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin","volume":"117","author":"Linde","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2012.06.013_bb0190","doi-asserted-by":"crossref","first-page":"29740","DOI":"10.1074\/jbc.M802856200","article-title":"A conserved Cys-loop receptor aspartate residue in the M3\u2013M4 cytoplasmic loop is required for GABAA receptor assembly","volume":"283","author":"Lo","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2012.06.013_bb0195","doi-asserted-by":"crossref","first-page":"31348","DOI":"10.1074\/jbc.M110.151449","article-title":"Glycosylation of {beta}2 subunits regulates GABAA receptor biogenesis and channel gating","volume":"285","author":"Lo","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2012.06.013_bb0200","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1535-7511.2008.01278.x","article-title":"Molecular pathology of genetic epilepsies associated with GABAA receptor subunit mutations","volume":"9","author":"Macdonald","year":"2009","journal-title":"Epilepsy Curr."},{"key":"10.1016\/j.nbd.2012.06.013_bb0205","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1177\/1756285610388693","article-title":"Aminoglycoside-induced mutation suppression (stop codon readthrough) as a therapeutic strategy for Duchenne muscular dystrophy","volume":"3","author":"Malik","year":"2010","journal-title":"Ther. Adv. Neurol. Disord."},{"key":"10.1016\/j.nbd.2012.06.013_bb0210","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nrm1310","article-title":"Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics","volume":"5","author":"Maquat","year":"2004","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0215","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1042\/bst0311243","article-title":"Intramembrane proteolysis and post-targeting functions of signal peptides","volume":"31","author":"Martoglio","year":"2003","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.nbd.2012.06.013_bb0220","doi-asserted-by":"crossref","first-page":"6636","DOI":"10.1093\/emboj\/16.22.6636","article-title":"Signal peptide fragments of preprolactin and HIV-1 p-gp160 interact with calmodulin","volume":"16","author":"Martoglio","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/j.nbd.2012.06.013_bb0225","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/nrn919","article-title":"Is there more to GABA than synaptic inhibition?","volume":"3","author":"Owens","year":"2002","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2012.06.013_bb0230","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0306-4522(00)00442-5","article-title":"GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain","volume":"101","author":"Pirker","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2012.06.013_bb0235","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1038\/338582a0","article-title":"Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology","volume":"338","author":"Pritchett","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2012.06.013_bb0240","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.pneurobio.2008.09.016","article-title":"Mechanisms of human inherited epilepsies","volume":"87","author":"Reid","year":"2009","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0245","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/00019052-200304000-00008","article-title":"The epidemiology of epilepsy revisited","volume":"16","author":"Sander","year":"2003","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0250","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1038\/nrn1388","article-title":"Genetic mechanisms that underlie epilepsy","volume":"5","author":"Steinlein","year":"2004","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2012.06.013_bb0255","doi-asserted-by":"crossref","first-page":"17536","DOI":"10.1073\/pnas.0708440104","article-title":"Reduced cortical inhibition in a mouse model of familial childhood absence epilepsy","volume":"104","author":"Tan","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2012.06.013_bb0260","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/296537a0","article-title":"Construction of a functional human suppressor tRNA gene: an approach to gene therapy for beta-thalassaemia","volume":"296","author":"Temple","year":"1982","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2012.06.013_bb0265","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1523\/JNEUROSCI.17-08-02728.1997","article-title":"Stoichiometry and assembly of a recombinant GABAA receptor subtype","volume":"17","author":"Tretter","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2012.06.013_bb0270","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.abb.2005.07.013","article-title":"Type I signal peptidase: an overview","volume":"441","author":"Tuteja","year":"2005","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.nbd.2012.06.013_bb0275","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/nbt1101-1067","article-title":"An infectious transfer and expression system for genomic DNA loci in human and mouse cells","volume":"19","author":"Wade-Martins","year":"2001","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.nbd.2012.06.013_bb0280","doi-asserted-by":"crossref","first-page":"e36","DOI":"10.1093\/nar\/gni035","article-title":"Simple and highly efficient BAC recombineering using galK selection","volume":"33","author":"Warming","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.nbd.2012.06.013_bb0285","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nature05756","article-title":"PTC124 targets genetic disorders caused by nonsense mutations","volume":"447","author":"Welch","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2012.06.013_bb0290","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1056\/NEJMoa022170","article-title":"Gentamicin-induced correction of CFTR function in patients with cystic fibrosis and CFTR stop mutations","volume":"349","author":"Wilschanski","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.nbd.2012.06.013_bb0295","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1523\/JNEUROSCI.3189-11.2012","article-title":"GABA signaling promotes synapse elimination and axon pruning in developing cortical inhibitory interneurons","volume":"32","author":"Wu","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2012.06.013_bb0300","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1242\/jcs.00651","article-title":"Intramembrane proteolysis by presenilin and presenilin-like proteases","volume":"116","author":"Xia","year":"2003","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.nbd.2012.06.013_bb0305","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/sj.clpt.6100012","article-title":"Aminoglycoside-induced translational read-through in disease: overcoming nonsense mutations by pharmacogenetic therapy","volume":"81","author":"Zingman","year":"2007","journal-title":"Clin. Pharmacol. Ther."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996112002288?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996112002288?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,30]],"date-time":"2019-06-30T12:10:45Z","timestamp":1561896645000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996112002288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":61,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0969996112002288"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2012.06.013","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}