{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T19:07:17Z","timestamp":1790104037120,"version":"4.0.1"},"reference-count":209,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["K08NS055880"],"award-info":[{"award-number":["K08NS055880"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.nbd.2013.08.010","type":"journal-article","created":{"date-parts":[[2013,8,19]],"date-time":"2013-08-19T13:03:20Z","timestamp":1376917400000},"page":"61-79","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":114,"special_numbering":"C","title":["Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon"],"prefix":"10.1016","volume":"60","author":[{"given":"Marek","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2013.08.010_bb0005","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1089\/neu.2006.0224","article-title":"Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury","volume":"24","author":"Ai","year":"2007","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0010","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0065-3233(04)71007-4","article-title":"Microtubules and MAPs","volume":"71","author":"Amos","year":"2005","journal-title":"Adv. Protein Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0015","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1038\/sj.cdd.4402171","article-title":"Changes in calcium dynamics following the reversal of the sodium\u2013calcium exchanger have a key role in AMPA receptor-mediated neurodegeneration via calpain activation in hippocampal neurons","volume":"14","author":"Ara\u00fajo","year":"2007","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.nbd.2013.08.010_bb0020","doi-asserted-by":"crossref","first-page":"C1159","DOI":"10.1152\/ajpcell.00207.2006","article-title":"Calpain 10: a mitochondrial calpain and its role in calcium-induced mitochondrial dysfunction","volume":"291","author":"Arrington","year":"2006","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0025","doi-asserted-by":"crossref","first-page":"4474","DOI":"10.1128\/MCB.20.12.4474-4481.2000","article-title":"Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division","volume":"20","author":"Arthur","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0030","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1128\/MCB.21.6.2213-2220.2001","article-title":"Disruption of the mouse \u03bc-calpain gene reveals an essential role in platelet function","volume":"21","author":"Azam","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0035","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.cell.2004.11.049","article-title":"Cleavage of the plasma membrane Na+\/Ca2+ exchanger in excitotoxicity","volume":"120","author":"Bano","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2013.08.010_bb0040","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/j.1469-7580.2008.00909.x","article-title":"Rapid loss of motor nerve terminals following hypoxia\u2013reperfusion injury occurs via mechanisms distinct from classic Wallerian degeneration","volume":"212","author":"Baxter","year":"2008","journal-title":"J. Anat."},{"key":"10.1016\/j.nbd.2013.08.010_bb0045","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1097\/NEN.0b013e3181da84db","article-title":"Mechanisms of axonal spheroid formation in central nervous system Wallerian degeneration","volume":"69","author":"Beirowski","year":"2010","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0050","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1152\/physrev.2001.81.3.1353","article-title":"Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues","volume":"81","author":"Bennett","year":"2001","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.nbd.2013.08.010_bb0055","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/j.resuscitation.2010.08.006","article-title":"Global incidences of out-of-hospital cardiac arrest and survival rates: systematic review of 67 prospective studies","volume":"81","author":"Berdowski","year":"2010","journal-title":"Resuscitation"},{"key":"10.1016\/j.nbd.2013.08.010_bb0060","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1083\/jcb.151.5.985","article-title":"\u03b2IV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system","volume":"151","author":"Berghs","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0065","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ceca.2009.10.003","article-title":"A proteomic study of calpain-3 and its involvement in limb girdle muscular dystrophy type 2a","volume":"46","author":"Bertipaglia","year":"2009","journal-title":"Cell Calcium"},{"key":"10.1016\/j.nbd.2013.08.010_bb0070","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/sj.jcbfm.9600595","article-title":"Mechanistic role of calpains in postischemic neurodegeneration","volume":"28","author":"Bevers","year":"2008","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2013.08.010_bb0075","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1111\/j.1471-4159.2008.05860.x","article-title":"Knockdown of m-calpain increases survival of primary hippocampal neurons following NMDA excitotoxicity","volume":"108","author":"Bevers","year":"2009","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0080","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.expneurol.2010.03.007","article-title":"RNAi targeting \u03bc-calpain increases neuron survival and preserves hippocampal function after global brain ischemia","volume":"224","author":"Bevers","year":"2010","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0085","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1097\/00005072-198109000-00005","article-title":"The fate of axonal debris in Wallerian degeneration of rat optic and sciatic nerves. Electron microscopy and immunofluorescence studies with neurofilament antisera","volume":"40","author":"Bignami","year":"1981","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0090","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0143-4160(88)90036-X","article-title":"Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules","volume":"9","author":"Billger","year":"1988","journal-title":"Cell Calcium"},{"key":"10.1016\/j.nbd.2013.08.010_bb0095","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1083\/jcb.98.1.320","article-title":"Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system","volume":"98","author":"Bloom","year":"1984","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0100","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/01.WCB.0000111614.19196.04","article-title":"Pathophysiology of cerebral ischemia and brain trauma: similarities and differences","volume":"24","author":"Bramlett","year":"2004","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2013.08.010_bb0110","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1042\/bj3230233","article-title":"Actin is cleaved during constitutive apoptosis","volume":"323","author":"Brown","year":"1997","journal-title":"Biochem. J."},{"key":"10.1016\/j.nbd.2013.08.010_bb0105","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1152\/jn.2001.85.2.900","article-title":"Axonal L-type Ca2+ channels and anoxic injury in rat CNS white matter","volume":"85","author":"Brown","year":"2001","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0115","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s00701-005-0674-4","article-title":"All roads lead to disconnection? \u2014 Traumatic axonal injury revisited","volume":"148","author":"B\u00fcki","year":"2006","journal-title":"Acta Neurochir. (Wien)"},{"key":"10.1016\/j.nbd.2013.08.010_bb0120","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/00005072-199904000-00007","article-title":"The role of calpain-mediated spectrin proteolysis in traumatically induced axonal injury","volume":"58","author":"B\u00fcki","year":"1999","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0125","doi-asserted-by":"crossref","first-page":"2825","DOI":"10.1523\/JNEUROSCI.20-08-02825.2000","article-title":"Cytochrome c release and caspase activation in traumatic axonal injury","volume":"20","author":"B\u00fcki","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0130","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1089\/089771503321532842","article-title":"Preinjury administration of the calpain inhibitor MDL-28170 attenuates traumatically induced axonal injury","volume":"20","author":"Buki","year":"2003","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0135","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/B978-0-12-407704-1.00004-X","article-title":"Actin isoforms in neuronal development and function","volume":"301","author":"Cheever","year":"2013","journal-title":"Int. Rev. Cell Mol. Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0140","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0002-9440(10)63303-2","article-title":"Long-term accumulation of amyloid-\u03b2, \u03b2-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma","volume":"165","author":"Chen","year":"2004","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0145","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/nrn1788","article-title":"Axon degeneration mechanisms: commonality amid diversity","volume":"6","author":"Coleman","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0150","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1146\/annurev-neuro-060909-153248","article-title":"Wallerian degeneration, Wlds, and Nmnat","volume":"33","author":"Coleman","year":"2010","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0155","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S0166-2236(02)02255-5","article-title":"Axon pathology in neurological disease: a neglected therapeutic target","volume":"25","author":"Coleman","year":"2002","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0160","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1002\/jnr.20170","article-title":"Calpain inhibitor 2 prevents axonal degeneration of opossum optic nerve fibers","volume":"77","author":"Couto","year":"2004","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0165","doi-asserted-by":"crossref","first-page":"5115","DOI":"10.3390\/molecules14125115","article-title":"Calpain inhibition reduces axolemmal leakage in traumatic axonal injury","volume":"14","author":"Czeiter","year":"2009","journal-title":"Molecules"},{"key":"10.1016\/j.nbd.2013.08.010_bb0170","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1007\/s00018-005-5097-0","article-title":"Spectrin and calpain: a \u2018target\u2019 and a \u2018sniper\u2019 in the pathology of neuronal cells","volume":"62","author":"Czogalla","year":"2005","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0175","doi-asserted-by":"crossref","first-page":"313","DOI":"10.2174\/187152708784936699","article-title":"Activation of calpain and caspase pathways in demyelination and neurodegeneration in animal model of multiple sclerosis","volume":"7","author":"Das","year":"2008","journal-title":"CNS Neurol. Disord. Drug Targets"},{"key":"10.1016\/j.nbd.2013.08.010_bb0180","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1152\/physrev.00048.2009","article-title":"Axon physiology","volume":"91","author":"Debanne","year":"2011","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.nbd.2013.08.010_bb0185","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0006-8993(73)90765-8","article-title":"The spatio-temporal pattern of Wallerian degeneration in mammalian peripheral nerves","volume":"53","author":"Donat","year":"1973","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0190","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.mcn.2008.06.008","article-title":"Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments","volume":"39","author":"Duflocq","year":"2008","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0195","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-213X-6-3","article-title":"m-Calpain is required for preimplantation embryonic development in mice","volume":"6","author":"Dutt","year":"2006","journal-title":"BMC Dev. Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0200","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/BF00686971","article-title":"Axonal damage in severe traumatic brain injury: an experimental study in cat","volume":"76","author":"Erb","year":"1988","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0205","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1152\/jn.1995.74.1.369","article-title":"Voltage-gated calcium channels in CNS white matter: role in anoxic injury","volume":"74","author":"Fern","year":"1995","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0210","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1523\/JNEUROSCI.20-04-01333.2000","article-title":"Evidence that Wallerian degeneration and localized axon degeneration induced by local neurotrophin deprivation do not involve caspases","volume":"20","author":"Finn","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0215","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/BF00965538","article-title":"Calpain-mediated proteolysis of microtubule associated proteins MAP1B and MAP2 in developing brain","volume":"16","author":"Fischer","year":"1991","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0220","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1111\/j.1460-9568.2004.03313.x","article-title":"Differential distribution of calpain small subunit 1 and 2 in rat brain","volume":"19","author":"Friedrich","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0225","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1749-6632.1975.tb19197.x","article-title":"Biochemical studies on the in vitro assembly and disassembly of microtubules","volume":"253","author":"Gaskin","year":"1975","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0230","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.expneurol.2010.07.025","article-title":"Targeting individual calpain isoforms for neuroprotection","volume":"226","author":"Geddes","year":"2010","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0235","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/ana.410120611","article-title":"Diffuse axonal injury and traumatic coma in the primate","volume":"12","author":"Gennarelli","year":"1982","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0240","doi-asserted-by":"crossref","first-page":"6445","DOI":"10.1523\/JNEUROSCI.15-10-06445.1995","article-title":"Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels","volume":"15","author":"George","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0245","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1021\/bi061504y","article-title":"Sequential degradation of \u03b1II and \u03b2II spectrin by calpain in glutamate or maitotoxin-stimulated cells","volume":"46","author":"Glantz","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.nbd.2013.08.010_bb0250","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jns.2004.03.010","article-title":"Wallerian degeneration as a window to peripheral neuropathy","volume":"220","author":"Glass","year":"2004","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0255","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0022-510X(02)00013-8","article-title":"Very early activation of m-calpain in peripheral nerve during Wallerian degeneration","volume":"196","author":"Glass","year":"2002","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0260","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1161\/01.STR.0000054048.22626.B9","article-title":"New light on white matter","volume":"34","author":"Goldberg","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2013.08.010_bb0265","doi-asserted-by":"crossref","first-page":"8501","DOI":"10.1016\/S0021-9258(18)93003-6","article-title":"Studies of the \u03b1-actinin\/actin interaction in the Z-disk by using calpain","volume":"266","author":"Goll","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0270","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1152\/physrev.00029.2002","article-title":"The calpain system","volume":"83","author":"Goll","year":"2003","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.nbd.2013.08.010_bb0275","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0361-9230(99)00098-2","article-title":"Discovery of nonerythroid spectrin to the demonstration of its key role in synaptic transmission","volume":"50","author":"Goodman","year":"1999","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.nbd.2013.08.010_bb0280","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0021-9258(18)51762-2","article-title":"A neutral, calcium-activated proteinase from the soluble fraction of rat brain","volume":"239","author":"Guroff","year":"1964","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0285","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.euroneuro.2011.08.008","article-title":"Cost of disorders of the brain in Europe 2010","volume":"21","author":"Gustavsson","year":"2011","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0290","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1523\/JNEUROSCI.06-11-03103.1986","article-title":"Distribution of calpains I and II in rat brain","volume":"6","author":"Hamakubo","year":"1986","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0295","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.1073\/pnas.87.8.3009","article-title":"Calmodulin and calcium-dependent protease I coordinately regulate the interaction of fodrin with actin","volume":"87","author":"Harris","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2013.08.010_bb0300","doi-asserted-by":"crossref","first-page":"27847","DOI":"10.1074\/jbc.M703168200","article-title":"Stomach-specific calpain, nCL-2\/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains","volume":"282","author":"Hata","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0305","doi-asserted-by":"crossref","first-page":"18200","DOI":"10.1016\/S0021-9258(18)55255-8","article-title":"In vitro proteolysis of brain spectrin by calpain I inhibits association of spectrin with ankyrin-independent membrane binding site(s)","volume":"266","author":"Hu","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0310","doi-asserted-by":"crossref","first-page":"341","DOI":"10.3233\/NRE-2007-22502","article-title":"The impact of traumatic brain injuries: a global perspective","volume":"22","author":"Hyder","year":"2007","journal-title":"NeuroRehabilitation"},{"key":"10.1016\/j.nbd.2013.08.010_bb0315","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S0006-8993(98)01214-1","article-title":"The role of voltage-gated Ca2+ channels in anoxic injury of spinal cord white matter","volume":"817","author":"Imaizumi","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0320","doi-asserted-by":"crossref","first-page":"4605","DOI":"10.1523\/JNEUROSCI.0515-03.2004","article-title":"Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors","volume":"24","author":"Iwata","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0325","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1023\/A:1018588114648","article-title":"Axonal cytoskeletal changes after non-disruptive axonal injury","volume":"26","author":"Jafari","year":"1997","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0330","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1089\/neu.1998.15.955","article-title":"Axonal cytoskeletal changes after nondisruptive axonal injury. II. Intermediate sized axons","volume":"15","author":"Jafari","year":"1998","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0335","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1046\/j.1471-4159.2000.0742101.x","article-title":"Calpain inhibitors confer biochemical, but not electrophysiological, protection against anoxia in rat optic nerves","volume":"74","author":"Jiang","year":"2000","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0340","doi-asserted-by":"crossref","first-page":"4679","DOI":"10.1073\/pnas.78.8.4679","article-title":"Rapid disassembly of cold-stable microtubules by calmodulin","volume":"78","author":"Job","year":"1981","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2013.08.010_bb0345","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1016\/0006-291X(89)91150-9","article-title":"Proteolysis of tau by calpain","volume":"163","author":"Johnson","year":"1989","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.nbd.2013.08.010_bb0350","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/sj.sc.3100807","article-title":"The applied neuropathology of human spinal cord injury","volume":"37","author":"Kakulas","year":"1999","journal-title":"Spinal Cord"},{"key":"10.1016\/j.nbd.2013.08.010_bb0355","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1111\/j.1471-4159.1983.tb08072.x","article-title":"Identification of Ca2+-activated neutral protease in the peripheral nerve and its effects on neurofilament degeneration","volume":"40","author":"Kamakura","year":"1983","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0360","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/jnr.490130306","article-title":"Calcium-activated neutral protease in the peripheral nerve, which requires \u03bcM order Ca2+, and its effect on the neurofilament triplet","volume":"13","author":"Kamakura","year":"1985","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0365","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.abb.2009.12.020","article-title":"Mitochondrial calpain system: an overview","volume":"495","author":"Kar","year":"2010","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.nbd.2013.08.010_bb0370","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1083\/jcb.97.6.1918","article-title":"Microinjection of Ca++-calmodulin causes a localized depolymerization of microtubules","volume":"97","author":"Keith","year":"1983","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0375","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.expneurol.2005.12.017","article-title":"Traumatic axonal injury in the perisomatic domain triggers ultrarapid secondary axotomy and Wallerian degeneration","volume":"198","author":"Kelley","year":"2006","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0380","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1038\/nm1229","article-title":"In vivo imaging of axonal degeneration and regeneration in the injured spinal cord","volume":"11","author":"Kerschensteiner","year":"2005","journal-title":"Nat. Med."},{"key":"10.1016\/j.nbd.2013.08.010_bb0385","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0074-7696(01)02003-4","article-title":"Functional specificity of actin isoforms","volume":"202","author":"Khaitlina","year":"2001","journal-title":"Int. Rev. Cytol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0390","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0006-3495(02)75397-6","article-title":"Role of the DNase-I-binding loop in dynamic properties of actin filament","volume":"82","author":"Khaitlina","year":"2002","journal-title":"Biophys. J."},{"key":"10.1016\/j.nbd.2013.08.010_bb0395","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.expneurol.2008.04.025","article-title":"Mechanically-induced membrane poration causes axonal beading and localized cytoskeletal damage","volume":"212","author":"Kilinc","year":"2008","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0400","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.expneurol.2009.07.014","article-title":"Mechanical membrane injury induces axonal beading through localized activation of calpain","volume":"219","author":"Kilinc","year":"2009","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0405","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s12640-010-9152-8","article-title":"Wallerian-like degeneration of central neurons after synchronized and geometrically registered mass axotomy in a three-compartmental microfluidic chip","volume":"19","author":"Kilinc","year":"2011","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0410","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1161\/CIRCULATIONAHA.111.018820","article-title":"Global variation in the relative burden of stroke and ischemic heart disease","volume":"124","author":"Kim","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.nbd.2013.08.010_bb0415","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1042\/bj3350589","article-title":"Purification of native p94, a muscle-specific calpain, and characterization of its autolysis","volume":"335","author":"Kinbara","year":"1998","journal-title":"Biochem. J."},{"key":"10.1016\/j.nbd.2013.08.010_bb0420","doi-asserted-by":"crossref","first-page":"6064","DOI":"10.1073\/pnas.0909794107","article-title":"Mechanisms of acute axonal degeneration in the optic nerve in vivo","volume":"107","author":"Kn\u00f6ferle","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2013.08.010_bb0425","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1083\/jcb.200110003","article-title":"\u03b2IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier","volume":"156","author":"Komada","year":"2002","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0430","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0891-0618(02)00102-3","article-title":"Calpain 3 is expressed in astrocytes of rat and Microcebus brain","volume":"25","author":"K\u00f6nig","year":"2003","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.nbd.2013.08.010_bb0435","doi-asserted-by":"crossref","first-page":"2352","DOI":"10.1074\/jbc.270.5.2352","article-title":"AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier","volume":"270","author":"Kordeli","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0440","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1016\/0306-4522(81)90088-9","article-title":"Ionic currents in the somatic membrane of rat dorsal root ganglion neurons\u2014I. Sodium currents","volume":"6","author":"Kostyuk","year":"1981","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2013.08.010_bb0445","first-page":"65","article-title":"Actin in axons: stable scaffolds and dynamic filaments","volume":"48","author":"Letourneau","year":"2009","journal-title":"Results Probl. Cell Differ."},{"key":"10.1016\/j.nbd.2013.08.010_bb0450","doi-asserted-by":"crossref","first-page":"RC16","DOI":"10.1523\/JNEUROSCI.19-14-j0002.1999","article-title":"Novel injury mechanism in anoxia and trauma of spinal cord white matter: glutamate release via reverse Na+-dependent glutamate transport","volume":"19","author":"Li","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0455","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0014-5793(98)01697-4","article-title":"Calpain-induced proteolysis of \u03b2-spectrins","volume":"443","author":"L\u00f6fvenberg","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1016\/j.nbd.2013.08.010_bb0460","doi-asserted-by":"crossref","first-page":"28525","DOI":"10.1074\/jbc.M100603200","article-title":"Characterization and expression of calpain 10. A novel ubiquitous calpain with nuclear localization","volume":"276","author":"Ma","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0465","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1089\/neu.2011.2060","article-title":"Short-duration treatment with the calpain inhibitor MDL-28170 does not protect axonal transport in an in vivo model of traumatic axonal injury","volume":"29","author":"Ma","year":"2012","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0470","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1089\/neu.2012.2473","article-title":"Calpastatin overexpression protects axonal transport in an in vivo model of traumatic axonal injury","volume":"29","author":"Ma","year":"2012","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0475","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.nbd.2013.03.009","article-title":"Calpains mediate axonal cytoskeleton disintegration during Wallerian degeneration","volume":"56","author":"Ma","year":"2013","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2013.08.010_bb0480","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1152\/physrev.1995.75.4.835","article-title":"Role of microtubule-associated proteins in the control of microtubule assembly","volume":"75","author":"Maccioni","year":"1995","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.nbd.2013.08.010_bb0485","doi-asserted-by":"crossref","first-page":"e1003001","DOI":"10.1371\/journal.pgen.1003001","article-title":"Calpain-5 mutations cause autoimmune uveitis, retinal neovascularization, and photoreceptor degeneration","volume":"8","author":"Mahajan","year":"2012","journal-title":"PLoS Genet."},{"key":"10.1016\/j.nbd.2013.08.010_bb0490","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/BF00686885","article-title":"Ultrastructure of striated muscle of the rat after temporary ischemia","volume":"37","author":"M\u00e4kitie","year":"1977","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0495","doi-asserted-by":"crossref","first-page":"8955","DOI":"10.1016\/S0021-9258(18)32150-1","article-title":"Purification and characterization of two forms of Ca2+-activated neutral protease from calf brain","volume":"258","author":"Malik","year":"1983","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0500","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0024-3205(87)90374-2","article-title":"Micromolar Ca2+ requiring protease from human platelets: purification, partial characterization and effect on the cytoskeletal proteins","volume":"40","author":"Malik","year":"1987","journal-title":"Life Sci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0505","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1016\/j.biocel.2006.06.005","article-title":"Detection and localization of calpain 3-like protease in a neuronal cell line: possible regulation of apoptotic cell death through degradation of nuclear I\u03baB\u03b1","volume":"38","author":"Marcilhac","year":"2006","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0510","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1161\/01.STR.29.1.152","article-title":"Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats","volume":"29","author":"Markgraf","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2013.08.010_bb0515","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-8993(02)03834-9","article-title":"Participation of neurofilament proteins in axonal dark degeneration of rat's optic nerves","volume":"969","author":"Marques","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0520","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/0006-8993(91)91471-C","article-title":"Calpain II in rat peripheral nerve","volume":"564","author":"Mata","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0525","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/(SICI)1097-0029(19960815)34:6<522::AID-JEMT4>3.0.CO;2-L","article-title":"Histopathological changes at central nodes of Ranvier after stretch-injury","volume":"34","author":"Maxwell","year":"1996","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.nbd.2013.08.010_bb0530","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1089\/neu.1997.14.603","article-title":"Loss of axonal microtubules and neurofilaments after stretch-injury to guinea pig optic nerve fibers","volume":"14","author":"Maxwell","year":"1997","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0535","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/BF00334880","article-title":"Ultrastructural evidence of axonal shearing as a result of lateral acceleration of the head in non-human primates","volume":"86","author":"Maxwell","year":"1993","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0540","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1089\/neu.1997.14.419","article-title":"A mechanistic analysis of nondisruptive axonal injury: a review","volume":"14","author":"Maxwell","year":"1997","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0545","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1089\/neu.1999.16.749","article-title":"Calpain activation and cytoskeletal protein breakdown in the corpus callosum of head-injured patients","volume":"16","author":"McCracken","year":"1999","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0550","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1093\/brain\/awq119","article-title":"Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice","volume":"133","author":"McGonigal","year":"2010","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2013.08.010_bb0555","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/brain\/awg061","article-title":"Axonal damage: a key predictor of outcome in human CNS diseases","volume":"126","author":"Medana","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2013.08.010_bb0560","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.ceca.2006.06.004","article-title":"Cellular and subcellular localization of Na+\u2013Ca2+ exchanger protein isoforms, NCX1, NCX2, and NCX3 in cerebral cortex and hippocampus of adult rat","volume":"41","author":"Minelli","year":"2007","journal-title":"Cell Calcium"},{"key":"10.1016\/j.nbd.2013.08.010_bb0565","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1590\/S0001-37652001000200008","article-title":"Watery and dark axons in Wallerian degeneration of the opossum's optic nerve: different patterns of cytoskeletal breakdown?","volume":"73","author":"Narciso","year":"2001","journal-title":"An. Acad. Bras. Cienc."},{"key":"10.1016\/j.nbd.2013.08.010_bb0570","doi-asserted-by":"crossref","first-page":"9960","DOI":"10.1523\/JNEUROSCI.2003-05.2005","article-title":"Na+-dependent sources of intra-axonal Ca2+ release in rat optic nerve during in vitro chemical ischemia","volume":"25","author":"Nikolaeva","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0575","doi-asserted-by":"crossref","first-page":"3367","DOI":"10.1083\/jcb.109.6.3367","article-title":"The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau","volume":"109","author":"Noble","year":"1989","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0580","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/(SICI)1097-0169(1997)36:2<125::AID-CM3>3.0.CO;2-8","article-title":"How calcium causes microtubule depolymerization","volume":"36","author":"O'Brien","year":"1997","journal-title":"Cell Motil. Cytoskeleton"},{"key":"10.1016\/j.nbd.2013.08.010_bb0585","doi-asserted-by":"crossref","first-page":"5230","DOI":"10.1523\/JNEUROSCI.0425-06.2006","article-title":"Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton","volume":"26","author":"Ogawa","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0590","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1093\/brain\/awg254","article-title":"Calpain inhibitors protect against axonal degeneration in a model of anti-ganglioside antibody-mediated motor nerve terminal injury","volume":"126","author":"O'Hanlon","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2013.08.010_bb0595","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1126\/science.1223899","article-title":"dSarm\/Sarm1 is required for activation of an injury-induced axon death pathway","volume":"337","author":"Osterloh","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.nbd.2013.08.010_bb0600","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1113\/jphysiol.2006.116798","article-title":"Complex interplay between glutamate receptors and intracellular Ca2+ stores during ischaemia in rat spinal cord white matter","volume":"577","author":"Ouardouz","year":"2006","journal-title":"J. Physiol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0605","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/ana.21533","article-title":"Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors","volume":"65","author":"Ouardouz","year":"2009","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0610","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/ana.21539","article-title":"Glutamate receptors on myelinated spinal cord axons: II. AMPA and GluR5 receptors","volume":"65","author":"Ouardouz","year":"2009","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0615","doi-asserted-by":"crossref","first-page":"10609","DOI":"10.1523\/JNEUROSCI.6429-11.2012","article-title":"A new concept: A\u03b21\u201342 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death","volume":"32","author":"Pannaccione","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0620","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1161\/01.STR.27.9.1641","article-title":"Cerebral white matter is highly vulnerable to ischemia","volume":"27","author":"Pantoni","year":"1996","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2013.08.010_bb0625","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/S0959-4388(00)00122-7","article-title":"Molecular domains of myelinated axons","volume":"10","author":"Peles","year":"2000","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0630","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/syn.890020111","article-title":"The ultrastructural localization of calcium-activated protease \u201ccalpain\u201d in rat brain","volume":"2","author":"Perlmutter","year":"1988","journal-title":"Synapse"},{"key":"10.1016\/j.nbd.2013.08.010_bb0635","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/cne.902960207","article-title":"Distribution of calcium-activated protease calpain in the rat brain","volume":"296","author":"Perlmutter","year":"1990","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0640","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s12035-008-8033-0","article-title":"Review of the multiple aspects of neurofilament functions, and their possible contribution to neurodegeneration","volume":"38","author":"Perrot","year":"2008","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0645","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/mus.20731","article-title":"Sources of axonal calcium loading during in vitro ischemia of rat dorsal roots","volume":"35","author":"Petrescu","year":"2007","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.nbd.2013.08.010_bb0650","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-8993(96)00113-8","article-title":"Characterization of a distinct set of intra-axonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability","volume":"722","author":"Pettus","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0655","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1089\/neu.1994.11.507","article-title":"Traumatically induced altered membrane permeability: its relationship to traumatically induced reactive axonal change","volume":"11","author":"Pettus","year":"1994","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0660","doi-asserted-by":"crossref","first-page":"270","DOI":"10.2174\/156802610790725489","article-title":"Calpains: attractive targets for the development of synthetic inhibitors","volume":"10","author":"Pietsch","year":"2010","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0665","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0306-4522(96)00483-6","article-title":"A calpain inhibitor attenuates cortical cytoskeletal protein loss after experimental traumatic brain injury in the rat","volume":"77","author":"Posmantur","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2013.08.010_bb0670","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1750-3639.1991.tb00050.x","article-title":"Traumatically induced axonal injury: pathogenesis and pathobiological implications","volume":"2","author":"Povlishock","year":"1992","journal-title":"Brain Pathol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0675","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/00001199-200501000-00008","article-title":"Update of neuropathology and neurological recovery after traumatic brain injury","volume":"20","author":"Povlishock","year":"2005","journal-title":"J. Head Trauma Rehabil."},{"key":"10.1016\/j.nbd.2013.08.010_bb0680","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/00005072-198305000-00002","article-title":"Axonal change in minor head injury","volume":"42","author":"Povlishock","year":"1983","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0685","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1097\/00005072-199704000-00003","article-title":"Impact acceleration injury in the rat: evidence for focal axolemmal change and related neurofilament sidearm alteration","volume":"56","author":"Povlishock","year":"1997","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0690","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.semcdb.2010.09.010","article-title":"Composition, assembly, and maintenance of excitable membrane domains in myelinated axons","volume":"22","author":"Rasband","year":"2011","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0695","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.2174\/092986706779010342","article-title":"Currently evaluated calpain and caspase inhibitors for neuroprotection in experimental brain ischemia","volume":"13","author":"Ray","year":"2006","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0700","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2174\/1568007033482887","article-title":"Calpain and its involvement in the pathophysiology of CNS injuries and diseases: therapeutic potential of calpain inhibitors for prevention of neurodegeneration","volume":"2","author":"Ray","year":"2003","journal-title":"Curr. Drug Targets CNS Neurol. Disord."},{"key":"10.1016\/j.nbd.2013.08.010_bb0705","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s13311-011-0037-1","article-title":"Inhibition of cysteine proteases in acute and chronic spinal cord injury","volume":"8","author":"Ray","year":"2011","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.nbd.2013.08.010_bb0710","doi-asserted-by":"crossref","first-page":"3934","DOI":"10.1523\/JNEUROSCI.14-06-03934.1994","article-title":"Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain","volume":"14","author":"Roberts-Lewis","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0715","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1002\/(SICI)1097-4598(200006)23:6<863::AID-MUS4>3.0.CO;2-0","article-title":"Traumatic injury to peripheral nerves","volume":"23","author":"Robinson","year":"2000","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.nbd.2013.08.010_bb0720","doi-asserted-by":"crossref","first-page":"3428","DOI":"10.1073\/pnas.93.8.3428","article-title":"Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat","volume":"93","author":"Saatman","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2013.08.010_bb0725","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/00004647-200301000-00004","article-title":"Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice","volume":"23","author":"Saatman","year":"2003","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2013.08.010_bb0730","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1432-1033.1978.tb12768.x","article-title":"Calcium-induced inactivation of microtubule formation in brain extracts. Presence of a calcium-dependent protease acting on polymerization-stimulating microtubule-associated proteins","volume":"92","author":"Sandoval","year":"1978","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0735","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1247\/csf.11.253","article-title":"Rapid proteolysis of brain MAP-1 related cytoskeleton-associated 350kd protein by purified calpain","volume":"11","author":"Sato","year":"1986","journal-title":"Cell Struct. Funct."},{"key":"10.1016\/j.nbd.2013.08.010_bb0740","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.pneurobio.2007.07.007","article-title":"Mechanisms of axon degeneration: from development to disease","volume":"83","author":"Saxena","year":"2007","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0745","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1042\/0264-6021:3620383","article-title":"A novel human small subunit of calpains","volume":"362","author":"Sch\u00e1d","year":"2002","journal-title":"Biochem. J."},{"key":"10.1016\/j.nbd.2013.08.010_bb0750","doi-asserted-by":"crossref","first-page":"13242","DOI":"10.1523\/JNEUROSCI.3376-09.2009","article-title":"Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury","volume":"29","author":"Schafer","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0755","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0006-8993(74)90002-X","article-title":"Calcium-induced degeneration of axoplasm in isolated segments of rat peripheral nerve","volume":"69","author":"Schlaepfer","year":"1974","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0760","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1111\/j.1471-4159.1984.tb12809.x","article-title":"Persistence of immunoreactive neurofilament protein breakdown products in transected rat sciatic nerve","volume":"43","author":"Schlaepfer","year":"1984","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0765","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/j.1471-4159.1985.tb05442.x","article-title":"An immunoblot study of neurofilament degradation in situ and during calcium-activated proteolysis","volume":"44","author":"Schlaepfer","year":"1985","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0770","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1111\/jnc.12144","article-title":"Brain injury-induced proteolysis is reduced in a novel calpastatin-overexpressing transgenic mouse","volume":"125","author":"Schoch","year":"2013","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0775","doi-asserted-by":"crossref","first-page":"6375","DOI":"10.1523\/JNEUROSCI.0922-10.2010","article-title":"Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals","volume":"30","author":"Schoenmann","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0780","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.bbrc.2004.09.223","article-title":"Characterization of the bovine neurofilament NF-M protein and cDNA sequence, and identification of in vitro and in vivo calpain cleavage sites","volume":"325","author":"Shaw","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.nbd.2013.08.010_bb0785","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.neuron.2005.10.019","article-title":"Neurofascins are required to establish axonal domains for salutatory conduction","volume":"48","author":"Sherman","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2013.08.010_bb0790","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S1474-4422(02)00042-X","article-title":"Hereditary motor and sensory neuropathies: a biological perspective","volume":"1","author":"Shy","year":"2002","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0795","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0896-6273(88)90076-1","article-title":"Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo","volume":"1","author":"Siman","year":"1988","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2013.08.010_bb0800","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0006-8993(85)90208-2","article-title":"Distribution of calpain I, an enzyme associated with degenerative activity, in rat brain","volume":"347","author":"Siman","year":"1985","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0805","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1523\/JNEUROSCI.22-03-00791.2002","article-title":"Traumatically induced axotomy adjacent to the soma does not result in acute neuronal death","volume":"22","author":"Singleton","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0810","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1177\/107385840000600611","article-title":"Axonal damage in traumatic brain injury","volume":"6","author":"Smith","year":"2000","journal-title":"Neuroscientist"},{"key":"10.1016\/j.nbd.2013.08.010_bb0815","doi-asserted-by":"crossref","first-page":"4263","DOI":"10.1523\/JNEUROSCI.19-11-04263.1999","article-title":"High tolerance and delayed elastic response of cultured axons to dynamic stretch injury","volume":"19","author":"Smith","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0820","doi-asserted-by":"crossref","first-page":"31158","DOI":"10.1074\/jbc.270.52.31158","article-title":"Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence","volume":"270","author":"Sorimachi","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0825","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1538\/expanim.59.549","article-title":"Expanding members and roles of the calpain superfamily and their genetically modified animals","volume":"59","author":"Sorimachi","year":"2010","journal-title":"Exp. Anim."},{"key":"10.1016\/j.nbd.2013.08.010_bb0830","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1002\/dneu.20552","article-title":"Cyclosporin-A treatment attenuates delayed cytoskeletal alterations and secondary axotomy following mild axonal stretch injury","volume":"67","author":"Staal","year":"2007","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0835","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1089\/neu.2008.0669","article-title":"Disruption of the ubiquitin proteasome system following axonal stretch injury accelerates progression to secondary axotomy","volume":"26","author":"Staal","year":"2009","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0840","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1111\/j.1471-4159.2009.06531.x","article-title":"Initial calcium release from intracellular stores followed by calcium dysregulation is linked to secondary axotomy following transient axonal stretch injury","volume":"112","author":"Staal","year":"2010","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0845","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/med.20242","article-title":"Drugs that target dynamic microtubules: a new molecular perspective","volume":"31","author":"Stanton","year":"2011","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.nbd.2013.08.010_bb0850","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-8993(97)00868-8","article-title":"Immunolocalization of the Na+\u2013Ca2+ exchanger in mammalian myelinated axons","volume":"776","author":"Steffensen","year":"1997","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0855","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1006\/exnr.2001.7818","article-title":"Intra-axonal neurofilament compaction does not evoke local axonal swelling in all traumatically injured axons","volume":"172","author":"Stone","year":"2001","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0860","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1089\/089771502753754073","article-title":"Caspase-3-mediated cleavage of amyloid precursor protein and formation of amyloid \u03b2 peptide in traumatic axonal injury","volume":"19","author":"Stone","year":"2002","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb0865","doi-asserted-by":"crossref","first-page":"113","DOI":"10.2174\/1566524043479220","article-title":"White matter injury mechanisms","volume":"4","author":"Stys","year":"2004","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.nbd.2013.08.010_bb0870","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jns.2005.03.031","article-title":"General mechanisms of axonal damage and its prevention","volume":"233","author":"Stys","year":"2005","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0875","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S0304-3940(02)00469-X","article-title":"Calpain-dependent neurofilament breakdown in anoxic and ischemic rat central axons","volume":"328","author":"Stys","year":"2002","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2013.08.010_bb0880","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0306-4522(97)00230-3","article-title":"Mechanisms of calcium and sodium fluxes in anoxic myelinated central nervous system axons","volume":"82","author":"Stys","year":"1998","journal-title":"Neuroscience"},{"issue":"Suppl. 1","key":"10.1016\/j.nbd.2013.08.010_bb0885","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.2337\/diabetes.53.2007.S12","article-title":"Structure, activation, and biology of calpain","volume":"53","author":"Suzuki","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.nbd.2013.08.010_bb0890","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.expneurol.2011.12.020","article-title":"Calcium dependence of damage to mouse motor nerve terminals following oxygen\/glucose deprivation","volume":"234","author":"Talbot","year":"2012","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0895","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1096\/fj.09-142844","article-title":"Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration","volume":"24","author":"Tang-Schomer","year":"2010","journal-title":"FASEB J."},{"key":"10.1016\/j.nbd.2013.08.010_bb0900","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.expneurol.2011.10.030","article-title":"Partial interruption of axonal transport due to microtubule breakage accounts for the formation of periodic varicosities after traumatic axonal injury","volume":"233","author":"Tang-Schomer","year":"2012","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0905","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1038\/sj.jcbfm.9600455","article-title":"Excitotoxic mechanisms of ischemic injury in myelinated white matter","volume":"27","author":"Tekk\u00f6k","year":"2007","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2013.08.010_bb0910","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1159\/000046187","article-title":"Ultrastructural changes of the neuromuscular junction in reperfusion injury","volume":"170","author":"T\u00f6mb\u00f6l","year":"2002","journal-title":"Cells Tissues Organs"},{"key":"10.1016\/j.nbd.2013.08.010_bb0915","doi-asserted-by":"crossref","first-page":"20775","DOI":"10.1074\/jbc.M313873200","article-title":"On the sequential determinants of calpain cleavage","volume":"279","author":"Tompa","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2013.08.010_bb0920","doi-asserted-by":"crossref","first-page":"3368","DOI":"10.1111\/j.1460-9568.2007.05943.x","article-title":"Calpain-mediated cleavage of collapsin response mediator protein(CRMP)-2 during neurite degeneration in mice","volume":"26","author":"Touma","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0925","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1172\/JCI34254","article-title":"Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease","volume":"118","author":"Trinchese","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2013.08.010_bb0930","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.nbd.2006.09.011","article-title":"Hypoxic injury of isolated axons is independent of ionotropic glutamate receptors","volume":"25","author":"Underhill","year":"2007","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2013.08.010_bb0935","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1146\/annurev.neuro.30.051606.094354","article-title":"Why is Wallerian degeneration in the CNS so slow?","volume":"30","author":"Vargas","year":"2007","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0940","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1242\/jcs.111.6.713","article-title":"Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis","volume":"111","author":"Villa","year":"1998","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0945","doi-asserted-by":"crossref","first-page":"10350","DOI":"10.1523\/JNEUROSCI.2339-09.2009","article-title":"Calpain mediates proteolysis of the voltage-gated sodium channel \u03b1-subunit","volume":"29","author":"von Reyn","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb0950","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.bbrc.2004.09.012","article-title":"Molecular cloning and characterization of rat and human calpain-5","volume":"324","author":"Waghray","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.nbd.2013.08.010_bb0955","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1038\/ncb2373","article-title":"ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation","volume":"13","author":"Wakatsuki","year":"2011","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0960","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1098\/rstl.1850.0021","article-title":"Experiments on the section of the glossopharyngeal and hypoglossal nerves of the frog, and observations of the alterations produced thereby in the structure of their primitive fibres","volume":"140","author":"Waller","year":"1850","journal-title":"Philos. Trans. R. Soc. Lond."},{"key":"10.1016\/j.nbd.2013.08.010_bb0965","doi-asserted-by":"crossref","first-page":"R221","DOI":"10.1016\/j.cub.2012.02.056","article-title":"Axon degeneration: where the Wlds things are","volume":"22","author":"Wang","year":"2012","journal-title":"Curr. Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0975","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1093\/jnen\/59.7.599","article-title":"Pathogenesis of axonal degeneration: parallels between Wallerian degeneration and vincristine neuropathy","volume":"59","author":"Wang","year":"2000","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0980","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/brain\/awh078","article-title":"Calpain inhibition protects against Taxol-induced sensory neuropathy","volume":"127","author":"Wang","year":"2004","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2013.08.010_bb0970","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1083\/jcb.201108111","article-title":"Axon degeneration: molecular mechanisms of a self-destruction pathway","volume":"196","author":"Wang","year":"2012","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2013.08.010_bb0985","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0006-8993(92)90806-K","article-title":"Ultrastructural concomitants of anoxic injury and early post-anoxic recovery in rat optic nerve","volume":"574","author":"Waxman","year":"1992","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2013.08.010_bb0990","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/0896-6273(89)90238-9","article-title":"Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons","volume":"3","author":"Westenbroek","year":"1989","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2013.08.010_bb0995","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1038\/sj.cdd.4401147","article-title":"The proapoptotic proteins Bax and Bak are not involved in Wallerian degeneration","volume":"10","author":"Whitmore","year":"2003","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.nbd.2013.08.010_bb1000","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1523\/JNEUROSCI.21-06-01923.2001","article-title":"Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels","volume":"21","author":"Wolf","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb1005","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1126\/science.1232251","article-title":"Actin, spectrin, and associated proteins form a periodic cytoskeletal structure in axons","volume":"339","author":"Xu","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.nbd.2013.08.010_bb1010","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1432-1033.1995.009_1.x","article-title":"Calpain-induced proteolysis of normal human tau and tau associated with paired helical filaments","volume":"233","author":"Yang","year":"1995","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.nbd.2013.08.010_bb1015","doi-asserted-by":"crossref","first-page":"7230","DOI":"10.1523\/JNEUROSCI.2125-04.2004","article-title":"\u03b2IV spectrins are essential for membrane stability and the molecular organization of nodes of Ranvier","volume":"24","author":"Yang","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb1020","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1111\/j.1460-9568.2007.05914.x","article-title":"Induction of autophagy in neurite degeneration of mouse superior cervical ganglion neurons","volume":"26","author":"Yang","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2013.08.010_bb1025","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0014-5793(84)81324-1","article-title":"Degradation of actin and vimentin by calpain II, a Ca2+-dependent cysteine proteinase, in bovine lens","volume":"170","author":"Yoshida","year":"1984","journal-title":"FEBS Lett."},{"key":"10.1016\/j.nbd.2013.08.010_bb1030","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1089\/neu.2012.2561","article-title":"Calpain 1 knockdown improves tissue sparing and functional outcomes following spinal cord injury in rats","volume":"30","author":"Yu","year":"2013","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2013.08.010_bb1035","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1056\/NEJMra043361","article-title":"Calpains and disease","volume":"352","author":"Zatz","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.nbd.2013.08.010_bb1040","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0896-6273(03)00429-X","article-title":"Involvement of the ubiquitin\u2013proteasome system in the early stages of Wallerian degeneration","volume":"39","author":"Zhai","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2013.08.010_bb1045","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1083\/jcb.143.5.1295","article-title":"AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing","volume":"143","author":"Zhou","year":"1998","journal-title":"J. Cell Biol."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996113002313?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996113002313?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T19:08:42Z","timestamp":1688411322000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996113002313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":209,"alternative-id":["S0969996113002313"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2013.08.010","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2013.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}