{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:23:52Z","timestamp":1786994632941,"version":"build-2736575974"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"American CADASIL Foundation"},{"name":"Daniel Nelson's family"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.nbd.2014.09.006","type":"journal-article","created":{"date-parts":[[2014,9,21]],"date-time":"2014-09-21T21:39:11Z","timestamp":1411335551000},"page":"189-203","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Stem cell factor and granulocyte colony-stimulating factor exhibit therapeutic effects in a mouse model of CADASIL"],"prefix":"10.1016","volume":"73","author":[{"given":"Xiao-Yun","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria E.","family":"Gonzalez-Toledo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austin","family":"Fagan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Ming","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanying","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Shu","family":"Piao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lila","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Ru","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2014.09.006_bb0005","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1046\/j.1440-1789.2003.00519.x","article-title":"Cerebral arterial pathology of CADASIL and CARASIL (Maeda syndrome)","volume":"23","author":"Arima","year":"2003","journal-title":"Neuropathology"},{"key":"10.1016\/j.nbd.2014.09.006_bb0010","first-page":"358","article-title":"Evaluation of brain apoptosis in a CADASIL postmortem case","volume":"28","author":"Battisti","year":"2009","journal-title":"Clin. Neuropathol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0015","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1161\/01.STR.24.1.122","article-title":"Autosomal dominant leukoencephalopathy and subcortical ischemic stroke. A clinicopathological study","volume":"24","author":"Baudrimont","year":"1993","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2014.09.006_bb0025","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/S0140-6736(95)91557-5","article-title":"Clinical spectrum of CADASIL: a study of 7 families. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy","volume":"346","author":"Chabriat","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2014.09.006_bb0020","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1161\/01.STR.31.8.1904","article-title":"Cerebral hemodynamics in CADASIL before and after acetazolamide challenge assessed with MRI bolus tracking","volume":"31","author":"Chabriat","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2014.09.006_bb0030","first-page":"29","article-title":"Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)","volume":"6","author":"Choudhary","year":"2013","journal-title":"J. Clin. Aesthet. Dermatol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0035","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1006\/exnr.2002.8004","article-title":"Modulated generation of neuronal cells from bone marrow by expansion and mobilization of circulating stem cells with in vivo cytokine treatment","volume":"177","author":"Corti","year":"2002","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1460-9568.2004.03813.x","article-title":"Doublecortin expression levels in adult brain reflect neurogenesis","volume":"21","author":"Couillard-Despres","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2014.09.006_bb0045","doi-asserted-by":"crossref","first-page":"e53546","DOI":"10.1371\/journal.pone.0053546","article-title":"A specialized microvascular domain in the mouse neural stem cell niche","volume":"8","author":"Culver","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.nbd.2014.09.006_bb0050","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1471-4159.2005.03319.x","article-title":"Neuroprotection by stem cell factor in rat cortical neurons involves AKT and NFkappaB","volume":"95","author":"Dhandapani","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2014.09.006_bb0055","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S1474-4422(07)70028-5","article-title":"Genetics of ischaemic stroke","volume":"6","author":"Dichgans","year":"2007","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0060","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/ana.410440506","article-title":"The phenotypic spectrum of CADASIL: clinical findings in 102 cases","volume":"44","author":"Dichgans","year":"1998","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0065","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1161\/01.STR.0000149949.92854.45","article-title":"Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy","volume":"36","author":"Dubroca","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2014.09.006_bb0070","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1161\/ATVBAHA.112.251736","article-title":"Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature","volume":"33","author":"Fouillade","year":"2013","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0075","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.brainres.2013.04.052","article-title":"Cerebral amyloidal angiopathy\u2014a disease with implications for neurology and psychiatry","volume":"1519","author":"Gahr","year":"2013","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2014.09.006_bb0080","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1073\/pnas.1016199109","article-title":"Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis","volume":"109","author":"Gomez-Gaviro","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2014.09.006_bb0085","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s00401-006-0116-2","article-title":"Notch3 ectodomain is a major component of granular osmiophilic material (GOM) in CADASIL","volume":"112","author":"Ishiko","year":"2006","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0090","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/bies.201000093","article-title":"Pathogenesis of CADASIL: transgenic and knock-out mice to probe function and dysfunction of the mutated gene, Notch3, in the cerebrovasculature","volume":"33","author":"Joutel","year":"2011","journal-title":"Bioessays"},{"key":"10.1016\/j.nbd.2014.09.006_bb0100","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/383707a0","article-title":"Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia","volume":"383","author":"Joutel","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2014.09.006_bb0105","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1006\/geno.1996.0615","article-title":"A human homolog of bacterial acetolactate synthase genes maps within the CADASIL critical region","volume":"38","author":"Joutel","year":"1996","journal-title":"Genomics"},{"key":"10.1016\/j.nbd.2014.09.006_bb0120","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/S0140-6736(97)08083-5","article-title":"Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients","volume":"350","author":"Joutel","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2014.09.006_bb0095","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1172\/JCI8047","article-title":"The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients","volume":"105","author":"Joutel","year":"2000","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2014.09.006_bb0110","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1016\/S0140-6736(01)07142-2","article-title":"Skin biopsy immunostaining with a Notch3 monoclonal antibody for CADASIL diagnosis","volume":"358","author":"Joutel","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2014.09.006_bb0115","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1172\/JCI39733","article-title":"Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease","volume":"120","author":"Joutel","year":"2010","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2014.09.006_bb0125","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1046\/j.1365-2990.1999.00198.x","article-title":"CADASIL: hereditary disease of arteries causing brain infarcts and dementia","volume":"25","author":"Kalimo","year":"1999","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0130","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/j.1471-4159.2004.02879.x","article-title":"Neuronal precursor-specific activity of a human doublecortin regulatory sequence","volume":"92","author":"Karl","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2014.09.006_bb0135","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1161\/CIRCULATIONAHA.105.563668","article-title":"Administration of hematopoietic cytokines in the subacute phase after cerebral infarction is effective for functional recovery facilitating proliferation of intrinsic neural stem\/progenitor cells and transition of bone marrow-derived neuronal cells","volume":"113","author":"Kawada","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.nbd.2014.09.006_bb0140","doi-asserted-by":"crossref","first-page":"e31960","DOI":"10.1371\/journal.pone.0031960","article-title":"S phase entry of neural progenitor cells correlates with increased blood flow in the young subventricular zone","volume":"7","author":"Lacar","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.nbd.2014.09.006_bb0145","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1161\/01.STR.0000163080.82766.eb","article-title":"Impaired cerebral vasoreactivity in a transgenic mouse model of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy arteriopathy","volume":"36","author":"Lacombe","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2014.09.006_bb0150","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1189\/jlb.0506309","article-title":"The bone marrow constitutes a reservoir of pericyte progenitors","volume":"80","author":"Lamagna","year":"2006","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0155","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s00401-003-0701-6","article-title":"Evaluation of diagnostic NOTCH3 immunostaining in CADASIL","volume":"106","author":"Lesnik Oberstein","year":"2003","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0160","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/alzrt67","article-title":"Stem cell factor and granulocyte colony-stimulating factor reduce beta-amyloid deposits in the brains of APP\/PS1 transgenic mice","volume":"3","author":"Li","year":"2011","journal-title":"Alzheimers Res. Ther."},{"key":"10.1016\/j.nbd.2014.09.006_bb0165","doi-asserted-by":"crossref","first-page":"E7","DOI":"10.3171\/2012.1.FOCUS11370","article-title":"Cerebral amyloid angiopathy-associated intracerebral hemorrhage: pathology and management","volume":"32","author":"Mehndiratta","year":"2012","journal-title":"Neurosurg. Focus."},{"key":"10.1016\/j.nbd.2014.09.006_bb0170","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1111\/j.1750-3639.2004.tb00078.x","article-title":"Fibrosis and stenosis of the long penetrating cerebral arteries: the cause of the white matter pathology in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy","volume":"14","author":"Miao","year":"2004","journal-title":"Brain Pathol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0175","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1006\/exnr.1993.1203","article-title":"Consequences of reduced cerebral blood flow in brain development. I. Gross morphology, histology, and callosal connectivity","volume":"124","author":"Miller","year":"1993","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0180","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.neuroscience.2009.05.004","article-title":"Crucial role for Ser133-phosphorylated form of cyclic AMP-responsive element binding protein signaling in the differentiation and survival of neural progenitors under chronic cerebral hypoperfusion","volume":"162","author":"Miyamoto","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2014.09.006_bb0185","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1093\/hmg\/ddm042","article-title":"The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo","volume":"16","author":"Monet","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2014.09.006_bb0190","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1093\/brain\/awp049","article-title":"Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain","volume":"132","author":"Monet-Lepretre","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2014.09.006_bb0195","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1093\/brain\/awt092","article-title":"Abnormal recruitment of extracellular matrix proteins by excess Notch3 ECD: a new pathomechanism in CADASIL","volume":"136","author":"Monet-Lepretre","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2014.09.006_bb0200","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1093\/brain\/awh282","article-title":"Long-term prognosis and causes of death in CADASIL: a retrospective study in 411 patients","volume":"127","author":"Opherk","year":"2004","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2014.09.006_bb0205","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1750-3639.2006.tb00561.x","article-title":"Hereditary cystatin C amyloid angiopathy: genetic, clinical, and pathological aspects","volume":"16","author":"Palsdottir","year":"2006","journal-title":"Brain Pathol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0210","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1161\/STROKEAHA.109.563726","article-title":"Bone marrow-derived progenitor cells in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy","volume":"41","author":"Pescini","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2014.09.006_bb0215","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1001\/archneur.62.7.1091","article-title":"Spectrum of mutations in biopsy-proven CADASIL: implications for diagnostic strategies","volume":"62","author":"Peters","year":"2005","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0220","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/jcbfm.2008.168","article-title":"The role of stem cell factor and granulocyte-colony stimulating factor in brain repair during chronic stroke","volume":"29","author":"Piao","year":"2009","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2014.09.006_bb0225","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/1471-2202-7-77","article-title":"Variability of doublecortin-associated dendrite maturation in adult hippocampal neurogenesis is independent of the regulation of precursor cell proliferation","volume":"7","author":"Plumpe","year":"2006","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.nbd.2014.09.006_bb0230","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/nn1657","article-title":"Pigment epithelium-derived factor is a niche signal for neural stem cell renewal","volume":"9","author":"Ramirez-Castillejo","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2014.09.006_bb0235","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s00401-009-0501-8","article-title":"Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies","volume":"118","author":"Revesz","year":"2009","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0250","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1097\/00005072-199709000-00001","article-title":"CADASIL: cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy","volume":"56","author":"Ruchoux","year":"1997","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0245","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1007\/BF00571504","article-title":"Systemic vascular smooth muscle cell impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy","volume":"89","author":"Ruchoux","year":"1995","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0240","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S0002-9440(10)63824-2","article-title":"Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy","volume":"162","author":"Ruchoux","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0255","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1172\/JCI23559","article-title":"The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis","volume":"115","author":"Schneider","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2014.09.006_bb0260","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1126\/science.1095505","article-title":"Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells","volume":"304","author":"Shen","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.nbd.2014.09.006_bb0265","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.stem.2008.07.026","article-title":"Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell\u2013cell interactions","volume":"3","author":"Shen","year":"2008","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.nbd.2014.09.006_bb0270","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.stem.2008.07.025","article-title":"A specialized vascular niche for adult neural stem cells","volume":"3","author":"Tavazoie","year":"2008","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.nbd.2014.09.006_bb0275","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1093\/brain\/awn364","article-title":"Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients","volume":"132","author":"Tikka","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2014.09.006_bb0280","doi-asserted-by":"crossref","first-page":"5544","DOI":"10.1182\/blood-2007-10-119073","article-title":"The combination of granulocyte colony-stimulating factor and stem cell factor significantly increases the number of bone marrow-derived endothelial cells in brains of mice following cerebral ischemia","volume":"111","author":"Toth","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.nbd.2014.09.006_bb0285","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1161\/01.STR.0000124124.69842.2d","article-title":"Positron emission tomography examination of cerebral blood flow and glucose metabolism in young CADASIL patients","volume":"35","author":"Tuominen","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2014.09.006_bb0290","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0925-4773(01)00469-5","article-title":"Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels","volume":"108","author":"Villa","year":"2001","journal-title":"Mech. Dev."},{"key":"10.1016\/j.nbd.2014.09.006_bb0295","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1161\/01.STR.0000245091.28429.6a","article-title":"Cortical neuronal apoptosis in CADASIL","volume":"37","author":"Viswanathan","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2014.09.006_bb0300","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1073\/pnas.82.5.1526","article-title":"Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factor","volume":"82","author":"Welte","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2014.09.006_bb0305","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/cne.22093","article-title":"Blood vessels form a migratory scaffold in the rostral migratory stream","volume":"516","author":"Whitman","year":"2009","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.nbd.2014.09.006_bb0310","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.1161\/STROKEAHA.107.486217","article-title":"Beneficial effects of hematopoietic growth factor therapy in chronic ischemic stroke in rats","volume":"38","author":"Zhao","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2014.09.006_bb0315","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1161\/STROKEAHA.106.476457","article-title":"Brain repair by hematopoietic growth factors in a rat model of stroke","volume":"38","author":"Zhao","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2014.09.006_bb0320","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/jcbfm.2008.124","article-title":"Age-dependent regenerative responses in the striatum and cortex after hypoxia\u2013ischemia","volume":"29","author":"Zhu","year":"2009","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.nbd.2014.09.006_bb0325","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0092-8674(90)90300-4","article-title":"Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium","volume":"63","author":"Zsebo","year":"1990","journal-title":"Cell"}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996114002782?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996114002782?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,29]],"date-time":"2018-09-29T11:01:13Z","timestamp":1538218873000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996114002782"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":65,"alternative-id":["S0969996114002782"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2014.09.006","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stem cell factor and granulocyte colony-stimulating factor exhibit therapeutic effects in a mouse model of CADASIL","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2014.09.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}