{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T18:51:18Z","timestamp":1789411878804,"version":"build-2803163510"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Huntington Society of Canada and Canadian Institutes for Health Research","award":["CIHR MOP-12699"],"award-info":[{"award-number":["CIHR MOP-12699"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1016\/j.nbd.2015.11.020","type":"journal-article","created":{"date-parts":[[2015,11,24]],"date-time":"2015-11-24T10:48:24Z","timestamp":1448362104000},"page":"62-74","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Differential changes in thalamic and cortical excitatory synapses onto striatal spiny projection neurons in a Huntington disease mouse model"],"prefix":"10.1016","volume":"86","author":[{"given":"Karolina","family":"Kolodziejczyk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn A.","family":"Raymond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2015.11.020_bb0005","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1523\/JNEUROSCI.3539-10.2011","article-title":"Differential electrophysiological changes in striatal output neurons in Huntington's disease","volume":"31","author":"Andr\u00e9","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0010","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0014-4886(03)00025-6","article-title":"Regulation of cell survival in the developing thalamus: an in vitro analysis","volume":"181","author":"Asavaritikrai","year":"2003","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2015.11.020_bb0015","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1515\/REVNEURO.2007.18.3-4.223","article-title":"Hypothalamic dysfunction and neuroendocrine and metabolic alterations in Huntington's disease: clinical consequences and therapeutic implications","volume":"18","author":"Aziz","year":"2007","journal-title":"Rev. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0020","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/cne.902990206","article-title":"Organization of the thalamostriatal projections in the rat, with special emphasis on the ventral striatum","volume":"299","author":"Berendse","year":"1990","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.nbd.2015.11.020_bb0025","article-title":"Differential synaptic and extrasynaptic glutamate-receptor alterations in striatal medium-sized spiny neurons of aged YAC128 Huntington's disease mice","volume":"6","author":"Botelho","year":"2014","journal-title":"PLoS Curr."},{"key":"10.1016\/j.nbd.2015.11.020_bb0030","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1523\/JNEUROSCI.23-03-00961.2003","article-title":"Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease","volume":"23","author":"Cepeda","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0035","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.pneurobio.2006.11.001","article-title":"The corticostriatal pathway in Huntington's disease","volume":"81","author":"Cepeda","year":"2007","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.nbd.2015.11.020_bb0040","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1111\/j.1460-9568.2008.06038.x","article-title":"Differential electrophysiological properties of dopamine D1 and D2 receptor-containing striatal medium-sized spiny neurons","volume":"27","author":"Cepeda","year":"2008","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0045","doi-asserted-by":"crossref","DOI":"10.1042\/AN20090058","article-title":"Genetic mouse models of Huntington's disease: focus on electrophysiological mechanisms","volume":"2","author":"Cepeda","year":"2010","journal-title":"ASN Neuro"},{"key":"10.1016\/j.nbd.2015.11.020_bb0050","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0168-0102(02)00020-2","article-title":"Cortical diffusible factors increase MAP-2 immunoreactive neuronal population in thalamic cultures","volume":"43","author":"Coronas","year":"2002","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.nbd.2015.11.020_bb0055","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.nbd.2013.11.013","article-title":"Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice","volume":"62","author":"Dau","year":"2014","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2015.11.020_bb0060","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.nbd.2013.08.009","article-title":"Loss of corticostriatal and thalamostriatal synaptic terminals precedes striatal projection neuron pathology in heterozygous Q140 Huntington's disease mice","volume":"60C","author":"Deng","year":"2013","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2015.11.020_bb0065","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3389\/fnsys.2014.00198","article-title":"Differential loss of thalamostriatal and corticostriatal input to striatal projection neuron types prior to overt motor symptoms in the Q140 knock-in mouse model of Huntington's disease","volume":"8","author":"Deng","year":"2014","journal-title":"Front. Syst. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0070","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0306-4522(96)00001-2","article-title":"Striatal and cortical projections of single neurons from the central lateral thalamic nucleus in the rat","volume":"72","author":"Deschenes","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2015.11.020_bb0075","doi-asserted-by":"crossref","first-page":"6483","DOI":"10.1523\/JNEUROSCI.0435-08.2008","article-title":"Corticostriatal and thalamostriatal synapses have distinctive properties","volume":"28","author":"Ding","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0080","doi-asserted-by":"crossref","first-page":"14610","DOI":"10.1523\/JNEUROSCI.1623-10.2010","article-title":"Cortical and thalamic innervation of direct and indirect pathway medium-sized spiny neurons in mouse striatum","volume":"30","author":"Doig","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0085","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1113\/jphysiol.2012.245233","article-title":"Heterogeneous properties of central lateral and parafascicular thalamic synapses in the striatum","volume":"591","author":"Ellender","year":"2013","journal-title":"J. Physiol."},{"key":"10.1016\/j.nbd.2015.11.020_bb0090","doi-asserted-by":"crossref","first-page":"3768","DOI":"10.1523\/JNEUROSCI.4356-06.2007","article-title":"Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease","volume":"27","author":"Fan","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0095","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1111\/j.1460-9568.2006.05177.x","article-title":"Difference in organization of corticostriatal and thalamostriatal synapses between patch and matrix compartments of rat neostriatum","volume":"24","author":"Fujiyama","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0100","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.mcn.2011.05.001","article-title":"Mechanisms underlying NMDA receptor synaptic\/extrasynaptic distribution and function","volume":"48","author":"Gladding","year":"2011","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0105","doi-asserted-by":"crossref","first-page":"3739","DOI":"10.1093\/hmg\/dds154","article-title":"Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model","volume":"21","author":"Gladding","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2015.11.020_bb0110","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1523\/JNEUROSCI.5473-08.2009","article-title":"Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease","volume":"29","author":"Graham","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0115","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/0166-2236(94)90074-4","article-title":"The specificity of the \u201cnonspecific\u201d midline and intralaminar thalamic nuclei","volume":"17","author":"Groenewegen","year":"1994","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0120","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/nn835","article-title":"Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways","volume":"5","author":"Hardingham","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0125","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1002\/j.1460-2075.1990.tb07423.x","article-title":"Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain","volume":"9","author":"Hofer","year":"1990","journal-title":"EMBO J."},{"key":"10.1016\/j.nbd.2015.11.020_bb0130","doi-asserted-by":"crossref","first-page":"7704","DOI":"10.1523\/JNEUROSCI.4694-13.2014","article-title":"Achieving high-frequency optical control of synaptic transmission","volume":"34","author":"Jackman","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0135","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1523\/JNEUROSCI.5687-08.2009","article-title":"Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease","volume":"29","author":"Joshi","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0140","first-page":"648","article-title":"An experimental approach towards the development of an in vitro cortical\u2013thalamic co-culture model","author":"Kanagasabapathi","year":"2011","journal-title":"Conf. Proc. IEEE Eng. Med. Biol. Soc."},{"key":"10.1016\/j.nbd.2015.11.020_bb0145","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1093\/cercor\/bhh185","article-title":"Thalamic atrophy in Huntington's disease co-varies with cognitive performance: a morphometric MRI analysis","volume":"15","author":"Kassubek","year":"2005","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.nbd.2015.11.020_bb0150","doi-asserted-by":"crossref","first-page":"3992","DOI":"10.1523\/JNEUROSCI.4129-11.2012","article-title":"Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons","volume":"32","author":"Kaufman","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0155","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0094562","article-title":"Striatal synaptic dysfunction and hippocampal plasticity deficits in the Hu97\/18 mouse model of Huntington disease","volume":"9","author":"Kolodziejczyk","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2015.11.020_bb0160","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/j.neuroscience.2005.07.013","article-title":"GABA(B) receptors at glutamatergic synapses in the rat striatum","volume":"136","author":"Lacey","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2015.11.020_bb0165","doi-asserted-by":"crossref","first-page":"4374","DOI":"10.1523\/JNEUROSCI.5519-06.2007","article-title":"Novel and distinct operational principles of intralaminar thalamic neurons and their striatal projections","volume":"27","author":"Lacey","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0170","doi-asserted-by":"crossref","DOI":"10.1002\/phy2.164","article-title":"Inhibitory collaterals in genetically identified medium spiny neurons in mouse primary corticostriatal cultures","volume":"1","author":"Lalchandani","year":"2013","journal-title":"Physiol. Rep."},{"key":"10.1016\/j.nbd.2015.11.020_bb0175","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1096\/fj.04-1789fje","article-title":"A maternal blood-borne factor promotes survival of the developing thalamus","volume":"19","author":"Landgraf","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.nbd.2015.11.020_bb0180","doi-asserted-by":"crossref","first-page":"25036","DOI":"10.1074\/jbc.M800963200","article-title":"The survival-promoting peptide Y-P30 enhances binding of pleiotrophin to syndecan-2 and -3 and supports its neuritogenic activity","volume":"283","author":"Landgraf","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2015.11.020_bb0185","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1002\/cne.23235","article-title":"Confocal laser scanning microscopy and ultrastructural study of VGLUT2 thalamic input to striatal projection neurons in rats","volume":"521","author":"Lei","year":"2013","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.nbd.2015.11.020_bb0190","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1460-9568.1995.tb01067.x","article-title":"The stimulation of thalamic neurite outgrowth by cortex-derived growth factors in vitro: the influence of cortical age and activity","volume":"7","author":"Lotto","year":"1995","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0195","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1111\/j.1460-9568.1997.tb00761.x","article-title":"A role for neurotrophins in the survival of murine embryonic thalamic neurons","volume":"9","author":"Lotto","year":"1997","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0200","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/0306-4522(96)00200-X","article-title":"Trophic and outgrowth-promoting effects of K(+)-induced depolarization on developing thalamic cells in organotypic culture","volume":"74","author":"Magowan","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2015.11.020_bb0205","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3389\/fnsys.2011.00026","article-title":"Dysregulated neuronal activity patterns implicate corticostriatal circuit dysfunction in multiple rodent models of Huntington's disease","volume":"5","author":"Miller","year":"2011","journal-title":"Front. Syst. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0210","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.neuron.2010.01.008","article-title":"Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice","volume":"65","author":"Milnerwood","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2015.11.020_bb0215","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.nbd.2012.05.013","article-title":"Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice","volume":"48","author":"Milnerwood","year":"2012","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2015.11.020_bb0220","doi-asserted-by":"crossref","first-page":"11221","DOI":"10.1523\/JNEUROSCI.2780-08.2008","article-title":"A dopaminergic axon lattice in the striatum and its relationship with cortical and thalamic terminals","volume":"28","author":"Moss","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0225","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1038\/nm.2056","article-title":"Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin","volume":"15","author":"Okamoto","year":"2009","journal-title":"Nat. Med."},{"key":"10.1016\/j.nbd.2015.11.020_bb0230","doi-asserted-by":"crossref","first-page":"3518","DOI":"10.1074\/jbc.M113.513945","article-title":"Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin","volume":"289","author":"Parsons","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2015.11.020_bb0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jneumeth.2011.05.029","article-title":"An embryonic culture system for the investigation of striatal medium spiny neuron dendritic spine development and plasticity","volume":"200","author":"Penrod","year":"2011","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.nbd.2015.11.020_bb0240","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3233\/JHD-2012-120006","article-title":"Hypothalamic and limbic system changes in Huntington's disease","volume":"1","author":"Peters\u00e9n","year":"2012","journal-title":"J. Huntingt. Dis."},{"key":"10.1016\/j.nbd.2015.11.020_bb0245","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.neuron.2014.05.032","article-title":"Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease","volume":"83","author":"Plotkin","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2015.11.020_bb0250","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/cne.21099","article-title":"Differential synaptology of vGluT2-containing thalamostriatal afferents between the patch and matrix compartments in rats","volume":"499","author":"Raju","year":"2006","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.nbd.2015.11.020_bb0255","article-title":"Hippocampal neurogenesis, cognitive deficits and affective disorder in Huntington's disease","volume":"874387","author":"Ransome","year":"2012","journal-title":"Neural Plast."},{"key":"10.1016\/j.nbd.2015.11.020_bb0260","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.neuroscience.2011.08.052","article-title":"Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function","volume":"198","author":"Raymond","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2015.11.020_bb0265","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0306-4522(96)00093-0","article-title":"Comparative study of brain-derived neurotrophic factor messenger RNA and protein at the cellular level suggests multiple roles in hippocampus, striatum and cortex","volume":"74","author":"Schmidt-Kastner","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2015.11.020_bb0270","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1046\/j.1460-9568.2003.02696.x","article-title":"Formation of dendritic spines in cultured striatal neurons depends on excitatory afferent activity","volume":"17","author":"Segal","year":"2003","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0275","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.nbd.2005.08.001","article-title":"Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease","volume":"21","author":"Shehadeh","year":"2006","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2015.11.020_bb0280","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1093\/hmg\/ddg169","article-title":"Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease","volume":"12","author":"Slow","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2015.11.020_bb0285","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.jneumeth.2006.07.007","article-title":"A rat brain slice preparation for characterizing both thalamostriatal and corticostriatal afferents","volume":"159","author":"Smeal","year":"2007","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.nbd.2015.11.020_bb0290","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1111\/j.1460-9568.2008.06505.x","article-title":"Differences in excitatory transmission between thalamic and cortical afferents to single spiny efferent neurons of rat dorsal striatum","volume":"28","author":"Smeal","year":"2008","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0295","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.tins.2004.07.004","article-title":"The thalamostriatal system: a highly specific network of the basal ganglia circuitry","volume":"27","author":"Smith","year":"2004","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0300","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3389\/fnsys.2014.00005","article-title":"The thalamostriatal system in normal and diseased states","volume":"8","author":"Smith","year":"2014","journal-title":"Front. Syst. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0305","doi-asserted-by":"crossref","first-page":"11126","DOI":"10.1523\/JNEUROSCI.6244-10.2011","article-title":"Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses","volume":"31","author":"Tapia","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2015.11.020_bb0310","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/0896-6273(93)90335-O","article-title":"Multiple promoters direct tissue-specific expression of the rat BDNF gene","volume":"10","author":"Timmusk","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2015.11.020_bb0315","doi-asserted-by":"crossref","first-page":"11655","DOI":"10.1523\/JNEUROSCI.0288-13.2013","article-title":"Aberrant restoration of spines and their synapses in L-DOPA-induced dyskinesia: involvement of corticostriatal but not thalamostriatal synapses","volume":"33","author":"Zhang","year":"2013","journal-title":"J. Neurosci."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096999611530098X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096999611530098X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T16:01:36Z","timestamp":1599840096000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S096999611530098X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":63,"alternative-id":["S096999611530098X"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2015.11.020","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential changes in thalamic and cortical excitatory synapses onto striatal spiny projection neurons in a Huntington disease mouse model","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2015.11.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}