{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:18:08Z","timestamp":1780499888520,"version":"3.54.1"},"reference-count":85,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.nbd.2016.12.005","type":"journal-article","created":{"date-parts":[[2016,12,6]],"date-time":"2016-12-06T17:15:42Z","timestamp":1481044542000},"page":"108-121","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Cooperative synthesis of dopamine by non-dopaminergic neurons as a compensatory mechanism in the striatum of mice with MPTP-induced Parkinsonism"],"prefix":"10.1016","volume":"98","author":[{"given":"Elena A.","family":"Kozina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandr R.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Y.","family":"Kurina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael V.","family":"Ugrumov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2016.12.005_bb0005","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s00429-010-0290-9","article-title":"Vasopressinergic neurons of the supraoptic nucleus in perinatal rats: reaction to osmotic stimulation and its regulation","volume":"215","author":"Abramova","year":"2011","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.nbd.2016.12.005_bb0010","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1111\/j.1471-4159.2008.05651.x","article-title":"Modeling Parkinson-like neurodegeneration via osmotic minipump delivery of MPTP and probenecid","volume":"107","author":"Alvarez-Fischer","year":"2008","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2016.12.005_bb0015","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.brainres.2011.01.101","article-title":"Increasing proportions of tyrosine hydroxylase-immunoreactive interneurons colocalize with choline acetyltransferase or vasoactive intestinal peptide in the developing rat cerebral cortex","volume":"1383","author":"Asmus","year":"2011","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0020","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1023\/A:1025015928129","article-title":"Cortical and striatal expression of tyrosine hydroxylase mRNA in neonatal and adult mice","volume":"23","author":"Baker","year":"2003","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0025","doi-asserted-by":"crossref","first-page":"6761","DOI":"10.1523\/JNEUROSCI.17-17-06761.1997","article-title":"Dopaminergic neurons intrinsic to the primate striatum","volume":"17","author":"Betarbet","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0030","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0166-2236(03)00038-9","article-title":"Presymptomatic compensation in Parkinson's disease is not dopamine-mediated","volume":"26","author":"Bezard","year":"2003","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0035","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1007\/s00429-013-0533-7","article-title":"Dynamic expression of tyrosine hydroxylase mRNA and protein in neurons of the striatum and amygdala of mice, and experimental evidence of their multiple embryonic origin","volume":"219","author":"Bupesh","year":"2014","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.nbd.2016.12.005_bb0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0044025","article-title":"Lack or inhibition of dopaminergic stimulation induces a development increase of striatal tyrosine hydroxylase-positive interneurons","volume":"7","author":"Busceti","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2016.12.005_bb0045","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1023\/A:1007572328295","article-title":"Synthesis and release of dopamine in rat striatal slices: requirement for exogenous tyrosine in the medium","volume":"25","author":"B\u00fcy\u00fckuysal","year":"2000","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0050","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0168-0102(99)00029-2","article-title":"Extrastriatal dopaminergic innervation of human basal ganglia","volume":"34","author":"Cossette","year":"1999","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchemneu.2004.08.007","article-title":"Morphology and distribution of dopaminergic neurons intrinsic to the human striatum","volume":"29","author":"Cossette","year":"2005","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.nbd.2016.12.005_bb0060","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/j.1460-9568.2008.06040.x","article-title":"Tyrosine hydroxylase cells appearing in the mouse striatum after dopamine denervation are likely to be projection neurones regulated by l-DOPA","volume":"27","author":"Darmopil","year":"2008","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0065","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0304-3940(87)90298-9","article-title":"Primate neostriatal neurons containing tyrosine hydroxylase: immunohistochemical evidence","volume":"75","author":"Dubach","year":"1987","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0070","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jchemneu.2005.04.001","article-title":"Degeneration of dopaminergic neurons triggers an expression of individual enzymes of dopamine synthesis in non-dopaminergic neurons of the arcuate nucleus in adult rats","volume":"30","author":"Ershov","year":"2005","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.nbd.2016.12.005_bb0075","doi-asserted-by":"crossref","first-page":"3413","DOI":"10.1073\/pnas.0409713102","article-title":"Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin\u2013proteasome system and alpha-synuclein","volume":"102","author":"Fornai","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2016.12.005_bb0080","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.brainres.2015.01.020","article-title":"Expression of ocular albinism 1 (OA1), 3, 4-dihydroxy-l-phenylalanine (DOPA) receptor, in both neuronal and non-neuronal organs","volume":"1602","author":"Fukuda","year":"2015","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0085","doi-asserted-by":"crossref","first-page":"3675","DOI":"10.1007\/s00429-015-1125-5","article-title":"Serotonin hyperinnervation of the striatum with high synaptic incidence in parkinsonian monkeys","volume":"221","author":"Gagnon","year":"2016","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.nbd.2016.12.005_bb0090","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1523\/JNEUROSCI.07-12-03915.1987","article-title":"The neostriatal mosaic: II. Patch-and matrix-directed mesostriatal dopaminergic and non-dopaminergic systems","volume":"7","author":"Gerfen","year":"1987","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0095","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1471-4159.1966.tb09873.x","article-title":"Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain","volume":"13","author":"Glowinski","year":"1966","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2016.12.005_bb0100","first-page":"427","article-title":"Immunohistochemical studies on localization and distribution of monoamine neuron systems in rat brain. I. Tyrosine hydroxylase in mesencephalon and diencephalon","volume":"54","author":"H\u00f6kfelt","year":"1976","journal-title":"Med. Biol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0105","first-page":"21","article-title":"Immunohistochemical studies on localization and distribution of monoamine neuron systems in rat brain. II. Tyrosine hydroxylase in telencephalon","volume":"55","author":"H\u00f6kfelt","year":"1977","journal-title":"Med. Biol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0110","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1093\/brain\/awl332","article-title":"The fate of striatal dopaminergic neurons in Parkinson's disease and Huntington's chorea","volume":"130","author":"Huot","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2016.12.005_bb0115","doi-asserted-by":"crossref","first-page":"6999","DOI":"10.1523\/JNEUROSCI.5996-09.2010","article-title":"Electrophysiological and morphological characteristics and synaptic connectivity of tyrosine hydroxylase-expressing neurons in adult mouse striatum","volume":"30","author":"Ib\u00e1\u00f1ez-Sandoval","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0120","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0304-3940(98)00103-7","article-title":"A dopamine-synthesizing cell group demonstrated in the human basal forebrain by dual labeling immunohistochemical technique of tyrosine hydroxylase and aromatic l-amino acid decarboxylase","volume":"243","author":"Ikemoto","year":"1998","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0125","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0006-8993(98)00661-1","article-title":"Do all of human midbrain tyrosine hydroxylase neurons synthesize dopamine?","volume":"805","author":"Ikemoto","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0130","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0304-3940(99)00409-7","article-title":"Tyrosine hydroxylase and aromatic l-amino acid decarboxylase do not coexist in neurons in the human anterior cingulate cortex","volume":"269","author":"Ikemoto","year":"1999","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0135","doi-asserted-by":"crossref","first-page":"7400","DOI":"10.1073\/pnas.87.19.7400","article-title":"mRNA coding for oxytocin is present in axons of the hypothalamo-neurohypophysial tract","volume":"87","author":"Jirikowski","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2016.12.005_bb0140","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.neulet.2004.02.068","article-title":"Striatal tyrosine hydroxylase immunoreactive neurons are induced by l-dihydroxyphenylalanine and nerve growth factor treatment in 6-hydroxydopamine lesioned rats","volume":"362","author":"Jollivet","year":"2004","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0145","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0006-8993(00)02758-X","article-title":"The 4F2hc\/LAT1 complex transports l-DOPA across the blood-brain barrier","volume":"879","author":"Kageyama","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0150","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0304-3940(92)90773-Z","article-title":"DOPA-decarboxylation in the striata of rats with unilateral substantia nigra lesions","volume":"147","author":"Kang","year":"1992","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0155","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.neulet.2006.03.059","article-title":"Reuptake of l-DOPA-derived extracellular dopamine in the striatum with dopaminergic denervation via serotonin transporters","volume":"402","author":"Kannari","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0160","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1267\/ahc.06019","article-title":"Tyrosine hydroxylase (TH) and aromatic-l-amino acid decarboxylase (AADC)-immunoreactive neurons of the common marmoset., Callithrix jacchus. Brain: an immunohistochemical analysis","volume":"40","author":"Karasawa","year":"2007","journal-title":"Acta Histochem. Cytochem."},{"key":"10.1016\/j.nbd.2016.12.005_bb0165","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0891-0618(98)00060-X","article-title":"Aromatic l-amino acid decarboxylase-and tyrosine hydroxylase-immunohistochemistry in the adult human hypothalamus","volume":"16","author":"Kitahama","year":"1998","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.nbd.2016.12.005_bb0170","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.jns.2014.03.028","article-title":"Tyrosine hydroxylase expression and activity in the nigrostriatal dopaminergic neurons of MPTP-treated mice at the presymptomatic and symptomatic stages of parkinsonism","volume":"340","author":"Kozina","year":"2014","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-3565(25)27006-9","article-title":"Elucidation of the rate-limiting step in norepinephrine biosynthesis in the perfused guinea-pig heart","volume":"148","author":"Levitt","year":"1965","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.nbd.2016.12.005_bb0180","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S0306-4522(00)00588-1","article-title":"Mechanisms of the effects of exogenous levodopa on the dopamine-denervated striatum","volume":"103","author":"Lopez","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0185","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0006-8993(03)02291-1","article-title":"Localization and functional significance of striatal neurons immunoreactive to aromatic l-amino acid decarboxylase or tyrosine hydroxylase in rat Parkinsonian models","volume":"969","author":"Lopez-Real","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0190","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.brainres.2005.04.019","article-title":"Serotonergic hyperinnervation into the dopaminergic denervated striatum compensates for dopamine conversion from exogenously administered l-DOPA","volume":"1046","author":"Maeda","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0195","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/311464a0","article-title":"Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism","volume":"311","author":"Markey","year":"1984","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2016.12.005_bb0200","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1111\/j.1460-9568.2011.07873.x","article-title":"Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum","volume":"34","author":"Masuda","year":"2011","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0205","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.neures.2014.07.008","article-title":"Localization of ocular albinism-1 gene product GPR143 in the rat central nervous system","volume":"88","author":"Masukawa","year":"2014","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0210","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.neuroscience.2014.04.024","article-title":"Ultrastructural localization of tyrosine hydroxylase in tree shrew nucleus accumbens core and shell","volume":"271","author":"McCollum","year":"2014","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0215","first-page":"59","article-title":"Do tyrosine hydroxylase-immunoreactive neurons in the ventrolateral arcuate nucleus produce dopamine or only l-dopa?","volume":"1","author":"Meister","year":"1988","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.nbd.2016.12.005_bb0220","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1006\/exnr.1994.1219","article-title":"Detection and regulation of tyrosine hydroxylase mRNA in catecholaminergic terminal fields: possible axonal compartmentalization","volume":"130","author":"Melia","year":"1994","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0225","doi-asserted-by":"crossref","first-page":"3585","DOI":"10.1046\/j.1460-9568.1999.00774.x","article-title":"Immunocytochemical characterization of catecholaminergic neurons in the rat striatum following dopamine-depleting lesions","volume":"11","author":"Meredith","year":"1999","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0230","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0165-6147(93)90082-U","article-title":"Is l-dopa an endogenous neurotransmitter?","volume":"14","author":"Misu","year":"1993","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0235","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S1054-3589(08)61019-4","article-title":"Neurotransmitter-like actions of l-DOPA","volume":"32","author":"Misu","year":"1995","journal-title":"Adv. Pharmacol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0240","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0163-7258(02)00325-X","article-title":"l-3,4-Dihydroxyphenylalanine as a neurotransmitter candidate in the central nervous system","volume":"97","author":"Misu","year":"2003","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.nbd.2016.12.005_bb0245","doi-asserted-by":"crossref","first-page":"12776","DOI":"10.1523\/JNEUROSCI.3463-09.2009","article-title":"Axonal transport defects in neurodegenerative diseases","volume":"29","author":"Morfini","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0250","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0306-4522(00)00154-8","article-title":"Striatal cells containing aromatic l-amino acid decarboxylase: an immunohistochemical comparison with other classes of striatal neurons","volume":"98","author":"Mura","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0255","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1023\/A:1019888300957","article-title":"Effect of MPTP on dopamine metabolism in Ames dwarf mice","volume":"27","author":"Muralikrishnan","year":"2002","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0260","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0006-8993(90)90224-Y","article-title":"Transient tyrosine hydroxylase-immunoreactive neurons in the region of the anterior olfactory nucleus of pre- and postnatal mice do not contain dopamine","volume":"511","author":"Nagatsu","year":"1990","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0265","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/S0306-4522(01)00441-9","article-title":"Neuronal ectopic expression of tyrosine hydroxylase in the mouse striatum by combined administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 3-nitropropionic acid","volume":"108","author":"Nakahara","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0270","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S0006-8993(98)00986-X","article-title":"Differential time courses of exogenous 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite MPP+ in the rat striatum and nucleus accumbens measured using in vivo voltammetry","volume":"812","author":"Nakazato","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0275","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0891-0618(97)10019-9","article-title":"Tyrosine hydroxylase-and\/or aromatic l-amino acid decarboxylase-containing cells in the suprachiasmatic nucleus of the Syrian hamster., Mesocricetus auratus","volume":"14","author":"Novak","year":"1998","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.nbd.2016.12.005_bb0280","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0165-0270(97)02227-9","article-title":"Persistent neuronal labeling by retrograde fluorescent tracers: a comparison between Fast Blue, Fluoro-Gold and various dextran conjugates","volume":"74","author":"Novikova","year":"1997","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.nbd.2016.12.005_bb0285","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.tins.2003.12.006","article-title":"How does Parkinson's disease begin? The role of compensatory mechanisms","volume":"27","author":"Obeso","year":"2004","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0290","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0304-3940(88)90683-0","article-title":"Comparative topography of dopamine-and tyrosine hydroxylase-immunoreactive neurons in the rat arcuate nucleus","volume":"95","author":"Okamura","year":"1988","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0295","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/0304-3940(88)90629-5","article-title":"l-DOPA-immunoreactive neurons in the rat hypothalamic tuberal region","volume":"95","author":"Okamura","year":"1988","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0300","doi-asserted-by":"crossref","first-page":"4942","DOI":"10.1523\/JNEUROSCI.22-12-04942.2002","article-title":"Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration","volume":"22","author":"Palfi","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0305","series-title":"The Mouse Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2001"},{"key":"10.1016\/j.nbd.2016.12.005_bb0310","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S0140-6736(00)02437-5","article-title":"New dopaminergic neurons in Parkinson's disease striatum","volume":"356","author":"Porritt","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2016.12.005_bb0315","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00401-004-0952-x","article-title":"Axonal transport defects: a common theme in neurodegenerative diseases","volume":"109","author":"Roy","year":"2005","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0320","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0304-3940(98)00198-0","article-title":"Sprouting of the serotonergic afferents into striatum after selective lesion of the dopaminergic system by MPTP in adult mice","volume":"245","author":"Rozas","year":"1998","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0325","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.neuroscience.2007.02.026","article-title":"On the use of retrograde tracers for identification of axon collaterals with multiple fluorescent retrograde tracers","volume":"146","author":"Schofield","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0330","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1093\/brain\/awl041","article-title":"New striatal dopamine neurons in MPTP-treated macaques result from a phenotypic shift and not neurogenesis","volume":"129","author":"Tand\u00e9","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2016.12.005_bb0335","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0304-3940(89)90655-1","article-title":"Striatal neurons with aromatic l-amino acid decarboxylase-like immunoreactivity in the rat","volume":"100","author":"Tashiro","year":"1989","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0340","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/0304-3940(89)90130-4","article-title":"Tyrosine hydroxylase-like immunoreactive neurons in the striatum of the rat","volume":"97","author":"Tashiro","year":"1989","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2016.12.005_bb0345","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0306-4522(95)00328-G","article-title":"Differential compartmentalization of vasopressin messenger RNA and neuropeptide within the rat hypothalamo-neurohypophysial axonal tracts: light and electron microscopic evidence","volume":"70","author":"Trembleau","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0350","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1124\/mol.61.4.729","article-title":"Transport of amino acid-related compounds mediated by l-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition","volume":"61","author":"Uchino","year":"2002","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0355","series-title":"Handbook of Neurochemistry and Molecular Neurobiology","first-page":"21","article-title":"Brain neurons partly expressing monoaminergic phenotype: distribution, development, and functional significance in norm and pathology","author":"Ugrumov","year":"2008"},{"key":"10.1016\/j.nbd.2016.12.005_bb0360","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jchemneu.2009.08.004","article-title":"Non-dopaminergic neurons partly expressing dopaminergic phenotype: distribution in the brain, development and functional significance","volume":"38","author":"Ugrumov","year":"2009","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.nbd.2016.12.005_bb0365","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/B978-0-12-411512-5.00004-X","article-title":"Brain neurons partly expressing dopaminergic phenotype: location, development, functional significance, and regulation","volume":"68","author":"Ugrumov","year":"2013","journal-title":"Adv. Pharmacol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0370","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.neuroscience.2004.01.002","article-title":"Dopamine synthesis by non-dopaminergic neurons expressing individual complementary enzymes of the dopamine synthetic pathway in the arcuate nucleus of fetal rats","volume":"124","author":"Ugrumov","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0375","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.neuroscience.2011.03.007","article-title":"Modeling of presymptomatic and symptomatic stages of parkinsonism in mice","volume":"181","author":"Ugrumov","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0380","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.neuroscience.2014.06.051","article-title":"Neurons expressing individual enzymes of dopamine synthesis in the mediobasal hypothalamus of adult rats: functional significance and topographic interrelations","volume":"277","author":"Ugrumov","year":"2014","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0385","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/0306-4522(84)90292-6","article-title":"Tyrosine hydroxylase immunoreactive neurons of the hypothalamus: a light and electron microscopic study","volume":"13","author":"Van den Pol","year":"1984","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2016.12.005_bb0390","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0361-9230(99)00229-4","article-title":"Recent techniques for tracing pathways in the central nervous system of developing and adult mammals","volume":"51","author":"Vercelli","year":"2000","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.nbd.2016.12.005_bb0395","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0006-8993(76)90057-3","article-title":"Regional concentrations of noradrenaline and dopamine in rat brain","volume":"113","author":"Versteeg","year":"1976","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2016.12.005_bb0400","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1152\/ajpcell.1998.275.1.C104","article-title":"Uptake and intracellular fate of l-DOPA in a human intestinal epithelial cell line: Caco-2","volume":"275","author":"Vieira-Coelho","year":"1998","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.nbd.2016.12.005_bb0405","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0003-2670(97)00619-3","article-title":"Comparative analysis of topographic distribution of acetylated histone H4 by using confocal microscopy and a deconvolution system","volume":"365","author":"Wako","year":"1998","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.nbd.2016.12.005_bb0410","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s10571-006-9053-9","article-title":"Three types of tyrosine hydroxylase-positive CNS neurons distinguished by dopa decarboxylase and VMAT2 co-expression","volume":"26","author":"Weihe","year":"2006","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0415","doi-asserted-by":"crossref","first-page":"6584","DOI":"10.1523\/JNEUROSCI.0195-15.2015","article-title":"Are striatal tyrosine hydroxylase interneurons dopaminergic?","volume":"35","author":"Xenias","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2016.12.005_bb0420","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1113\/jphysiol.2010.203257","article-title":"l-Dopa activates histaminergic neurons","volume":"589","author":"Yanovsky","year":"2011","journal-title":"J. Physiol."},{"key":"10.1016\/j.nbd.2016.12.005_bb0425","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/0006-8993(91)90675-L","article-title":"Compartments in rat dorsal and ventral striatum revealed following injection of 6-hydroxydopamine into the ventral mesencephalon","volume":"552","author":"Zahm","year":"1991","journal-title":"Brain Res."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996116302868?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996116302868?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T06:06:48Z","timestamp":1749794808000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996116302868"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":85,"alternative-id":["S0969996116302868"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2016.12.005","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cooperative synthesis of dopamine by non-dopaminergic neurons as a compensatory mechanism in the striatum of mice with MPTP-induced Parkinsonism","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2016.12.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}