{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T16:04:24Z","timestamp":1790438664128,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.nbd.2018.08.020","type":"journal-article","created":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T12:45:21Z","timestamp":1536324321000},"page":"151-164","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["Time- and sex-dependent efficacy of magnesium sulfate to prevent behavioral impairments and cerebral damage in a mouse model of cerebral palsy"],"prefix":"10.1016","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1574-120X","authenticated-orcid":false,"given":"Isma\u00ebl","family":"Daher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9r\u00e9nice","family":"Le Dieu-Lugon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryline","family":"Lecointre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Dupr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Voisin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Leroux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Dourmap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno J.","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Marret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Leroux-Nicollet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2451-8387","authenticated-orcid":false,"given":"Carine","family":"Cleren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2018.08.020_bb0005","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/s12974-014-0153-z","article-title":"The immune response after hypoxia-ischemia in a mouse model of preterm brain injury","volume":"11","author":"Albertsson","year":"2014","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.nbd.2018.08.020_bb0010","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/ana.24132","article-title":"Brain injury in premature neonates: a primary cerebral dysmaturation disorder?","volume":"75","author":"Back","year":"2014","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0015","doi-asserted-by":"crossref","first-page":"4310","DOI":"10.1093\/cercor\/bhu331","article-title":"Thalamocortical connectivity predicts cognition in children born preterm","volume":"25","author":"Ball","year":"2015","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.nbd.2018.08.020_bb0020","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/B978-0-12-420170-5.00007-6","article-title":"Mechanisms of synaptic plasticity and recognition memory in the perirhinal cortex","volume":"122","author":"Banks","year":"2014","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"key":"10.1016\/j.nbd.2018.08.020_bb0025","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1001\/jama.296.13.1602","article-title":"Clinical and MRI correlates of cerebral palsy: the European Cerebral Palsy Study","volume":"296","author":"Bax","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.nbd.2018.08.020_bb0030","doi-asserted-by":"crossref","first-page":"382e1","DOI":"10.1016\/j.ajog.2016.03.032","article-title":"Maternal magnesium sulfate fetal neuroprotective effects to the fetus: inhibition of neuronal nitric oxide synthase and nuclear factor kappa-light-chain-enhancer of activated B cells activation in a rodent model","volume":"215","author":"Beloosesky","year":"2016","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0035","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1161\/STROKEAHA.114.005324","article-title":"Recognition memory impairments after subcortical white matter stroke in mice","volume":"45","author":"Blasi","year":"2014","journal-title":"Stroke"},{"key":"10.1016\/j.nbd.2018.08.020_bb0040","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0197-0186(00)00029-2","article-title":"Ischemia induced changes in expression of the astrocyte glutamate transporter GLT1 in hippocampus of the rat","volume":"37","author":"Bruhn","year":"2000","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.nbd.2018.08.020_bb0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0118889","article-title":"Hypoxia-ischemia and therapeutic hypothermia in the neonatal mouse brain\u2014a longitudinal study","volume":"10","author":"Burnsed","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2018.08.020_bb0050","doi-asserted-by":"crossref","first-page":"g6661","DOI":"10.1136\/bmj.g6661","article-title":"Preterm birth and the role of neuroprotection","volume":"350","author":"Chang","year":"2015","journal-title":"BMJ"},{"key":"10.1016\/j.nbd.2018.08.020_bb0055","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.jpeds.2014.04.007","article-title":"School-age outcomes following a randomized controlled trial of magnesium sulfate for neuroprotection of preterm infants","volume":"165","author":"Chollat","year":"2014","journal-title":"J. Pediatr."},{"key":"10.1016\/j.nbd.2018.08.020_bb0060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0079982","article-title":"Magnesium sulfate protects against the bioenergetic consequences of chronic glutamate receptor stimulation","volume":"8","author":"Clerc","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2018.08.020_bb0065","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/S0140-6736(13)61835-8","article-title":"Cerebral palsy","volume":"383","author":"Colver","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2018.08.020_bb0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002398","article-title":"AMICABLE Group. Assessing the neuroprotective benefits for babies of antenatal magnesium sulphate: An individual participant data meta-analysis","volume":"14","author":"Crowther","year":"2017","journal-title":"PLoS Med."},{"key":"10.1016\/j.nbd.2018.08.020_bb0075","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1093\/jnen\/nlx073","article-title":"Magnesium sulfate prevents neurochemical and long-term behavioural consequences of neonatal excitotoxic lesions: comparison between male and female mice","volume":"76","author":"Daher","year":"2017","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0080","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1542\/peds.2008-1216","article-title":"Behavioral problems and cognitive performance at 5 years of age after very preterm birth: the EPIPAGE Study","volume":"123","author":"Delobel-Ayoub","year":"2009","journal-title":"Pediatrics"},{"issue":"Issue 1. Art","key":"10.1016\/j.nbd.2018.08.020_bb0085","article-title":"Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus","author":"Doyle","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.nbd.2018.08.020_bb0090","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1001\/jama.2014.11189","article-title":"Australasian Collaborative Trial of Magnesium Sulphate (ACTOMgSO4) Study Group. School-age outcomes of very preterm infants after antenatal treatment with magnesium sulfate vs placebo","volume":"312","author":"Doyle","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.nbd.2018.08.020_bb0095","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000201327","article-title":"High dose magnesium sulfate exposure induces apoptotic cell death in the developing neonatal mouse brain","volume":"96","author":"Dribben","year":"2009","journal-title":"Neonatology."},{"key":"10.1016\/j.nbd.2018.08.020_bb0100","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1002\/ana.22489","article-title":"Systemic inflammation disrupts the developmental program of white matter","volume":"70","author":"Favrais","year":"2011","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0105","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/s13311-016-0422-x","article-title":"Reorganization of intact descending motor circuits to replace lost connections after injury","volume":"13","author":"Fink","year":"2016","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.nbd.2018.08.020_bb0110","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/S1474-4422(12)70058-3","article-title":"Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy?","volume":"11","author":"Fleiss","year":"2012","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0115","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0003-3472(65)90041-2","article-title":"Reflex-ontogeny and behavioural development of the mouse","volume":"13","author":"Fox","year":"1965","journal-title":"Anim. Behav."},{"key":"10.1016\/j.nbd.2018.08.020_bb0120","series-title":"The Mouse Brain in Stereotaxic Coordinates","author":"Franklin","year":"1997"},{"key":"10.1016\/j.nbd.2018.08.020_bb0125","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/dmcn.13629","article-title":"Complex interactions between hypoxia-ischemia and inflammation in preterm brain injury","volume":"60","author":"Galinsky","year":"2018","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0130","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/S0959-4388(05)80043-1","article-title":"Basal ganglia\u2014input, neural activity, and relation to the cortex","volume":"1","author":"Graybiel","year":"1991","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0135","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/nrneurol.2015.13","article-title":"The role of inflammation in perinatal brain injury","volume":"11","author":"Hagberg","year":"2015","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0140","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1053\/ob.1996.v175.a74408","article-title":"Effect of magnesium sulfate on excitatory amino acid receptors in the rat brain. I. N-methyl-D-aspartate receptor channel complex","volume":"175","author":"Hallak","year":"1996","journal-title":"Am J Obstet Gynecol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0145","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/0014-4886(88)90226-9","article-title":"Seizures and recovery from experimental brain damage","volume":"102","author":"Hernandez","year":"1988","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0150","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1126\/science.283.5398.70","article-title":"Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain","volume":"283","author":"Ikonomidou","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.nbd.2018.08.020_bb0155","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ejpn.2016.07.007","article-title":"Cerebral plasticity: Windows of opportunity in the developing brain","volume":"21","author":"Ismail","year":"2017","journal-title":"Eur. J. Paediatr. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0160","unstructured":"Koning G, Lyngfelt E, Svedin P, Leverin AL, Jinnai M, Gressens P, Thornton C, Wang X, Mallard C, Hagberg H. Magnesium sulphate induces preconditioning in preterm rodent models of cerebral hypoxia-ischemia. Int. J. Dev. Neurosci. 2018; pii: S0736\u20135748(17)30324\u201330326."},{"key":"10.1016\/j.nbd.2018.08.020_bb0165","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/pr.2017.75","article-title":"Effects of therapeutic hypothermia on white matter injury from murine neonatal hypoxia-ischemia","volume":"82","author":"Koo","year":"2017","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.nbd.2018.08.020_bb0170","doi-asserted-by":"crossref","DOI":"10.1002\/prp2.315","article-title":"Experimental and clinical evidence of differential effects of magnesium sulfate on neuroprotection and angiogenesis in the fetal brain","volume":"5","author":"Lecuyer","year":"2017","journal-title":"Pharmacol. Res. Perspect."},{"issue":"3","key":"10.1016\/j.nbd.2018.08.020_bb0175","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1097\/00005072-199505000-00009","article-title":"Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions","author":"Marret","year":"1995","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0180","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/B978-0-444-52891-9.00016-6","article-title":"Pathophysiology of cerebral palsy","volume":"111","author":"Marret","year":"2013","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0185","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/jnr.23828","article-title":"Sex-dependent consequences of neonatal brain hypoxia-ischemia in the rat","volume":"95","author":"Netto","year":"2017","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.nbd.2018.08.020_bb0190","series-title":"Atlas of the developing mouse brain at E17.5, P0 and P6","author":"Paxinos","year":"2007"},{"key":"10.1016\/j.nbd.2018.08.020_bb0195","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.nbd.2015.10.012","article-title":"Controversies in preterm brain injury","volume":"92","author":"Penn","year":"2016","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2018.08.020_bb0200","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic-ischemic brain damage in the rat","volume":"9","author":"Rice","year":"1981","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0205","first-page":"396","article-title":"Neonatal loss of gamma-aminobutyric acid pathway expression after human perinatal brain injury","volume":"104","author":"Robinson","year":"2006","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.nbd.2018.08.020_bb0210","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2016.00057","article-title":"Rodent hypoxia-ischemia models for cerebral palsy research: a systematic review","volume":"7","author":"Rumajogee","year":"2016","journal-title":"Front. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0215","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1134\/S0006297915110012","article-title":"Mechanisms of apoptosis","volume":"80","author":"Savitskaya","year":"2015","journal-title":"Biochemistry (Mosc)"},{"key":"10.1016\/j.nbd.2018.08.020_bb0220","doi-asserted-by":"crossref","first-page":"6338","DOI":"10.4049\/jimmunol.1101765","article-title":"Magnesium decreases inflammatory cytokine production: a novel innate immunomodulatory mechanism","volume":"188","author":"Sugimoto","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0225","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1002\/tox.22178","article-title":"Neurodevelopmental consequences of gestational and lactational exposure to pyrethroids in rats","volume":"31","author":"Syed","year":"2016","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0230","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0166-4328(03)00146-3","article-title":"Brain injury and neurofunctional deficit in neonatal mice with hypoxic-ischemic encephalopathy","volume":"145","author":"Ten","year":"2003","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.nbd.2018.08.020_bb0235","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.pediatrneurol.2015.01.016","article-title":"Pathophysiology and neuroprotection of global and focal perinatal brain injury: lessons from animal models","volume":"52","author":"Titomanlio","year":"2015","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0240","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1042\/BST20130284","article-title":"Brain damage of the preterm infant: new insights into the role of inflammation","volume":"42","author":"Van Steenwinckel","year":"2014","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.nbd.2018.08.020_bb0245","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1242\/jeb.01064","article-title":"Hypoxia-ischemia in the immature brain","volume":"207","author":"Vannucci","year":"2004","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0250","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S1474-4422(08)70294-1","article-title":"Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances","volume":"8","author":"Volpe","year":"2009","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nbd.2018.08.020_bb0255","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1542\/peds.2006-1416","article-title":"Improved neurodevelopmental outcomes for extremely low birth weight infants in 2000-2002","volume":"119","author":"Wilson-Costello","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.nbd.2018.08.020_bb0260","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/sj.cdd.4401545","article-title":"The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia","volume":"12","author":"Zhu","year":"2005","journal-title":"Cell Death Differ."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996118305126?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996118305126?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T08:05:44Z","timestamp":1539072344000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996118305126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":52,"alternative-id":["S0969996118305126"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2018.08.020","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Time- and sex-dependent efficacy of magnesium sulfate to prevent behavioral impairments and cerebral damage in a mouse model of cerebral palsy","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2018.08.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}