{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:04:13Z","timestamp":1790665453925,"version":"4.1.0"},"reference-count":84,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"am","delay-in-days":274,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002915","name":"Fondation pour la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002915","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008211","name":"Association France Parkinson","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008211","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.nbd.2019.104506","type":"journal-article","created":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T09:04:22Z","timestamp":1560762262000},"page":"104506","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Differential enhancement of ERK, PKA and Ca2+ signaling in direct and indirect striatal neurons of Parkinsonian mice"],"prefix":"10.1016","volume":"130","author":[{"given":"Louise-Laure","family":"Mariani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Longueville","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Antoine","family":"Girault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Herv\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1924-2443","authenticated-orcid":false,"given":"Nicolas","family":"Gervasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2019.104506_bb0005","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/0166-2236(89)90074-X","article-title":"The functional anatomy of basal ganglia disorders","volume":"12","author":"Albin","year":"1989","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0010","doi-asserted-by":"crossref","first-page":"5900","DOI":"10.1523\/JNEUROSCI.0837-12.2012","article-title":"G\u03b1(olf) mutation allows parsing the role of cAMP-dependent and extracellular signal-regulated kinase-dependent signaling in L-3,4-dihydroxyphenylalanine-induced dyskinesia","volume":"32","author":"Alcacer","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0015","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1172\/JCI90132","article-title":"Chemogenetic stimulation of striatal projection neurons modulates responses to Parkinson's disease therapy","volume":"127","author":"Alcacer","year":"2017","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2019.104506_bb0020","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.bbrc.2006.07.136","article-title":"Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters","volume":"348","author":"Allen","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.nbd.2019.104506_bb0025","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1007\/s11064-011-0461-y","article-title":"GluR1 phosphorylation and persistent expression of levodopa-induced motor response alterations in the Hemi-Parkinsonian rat","volume":"36","author":"Ba","year":"2011","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.nbd.2019.104506_bb0030","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0896-6273(00)80435-3","article-title":"Mice deficient in G(olf) are anosmic","volume":"20","author":"Belluscio","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2019.104506_bb0035","doi-asserted-by":"crossref","first-page":"5671","DOI":"10.1523\/JNEUROSCI.1039-08.2008","article-title":"Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol","volume":"28","author":"Bertran-Gonzalez","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0040","doi-asserted-by":"crossref","first-page":"6143","DOI":"10.1523\/JNEUROSCI.5851-09.2010","article-title":"Type 4 phosphodiesterase plays different integrating roles in different cellular domains in pyramidal cortical neurons","volume":"30","author":"Castro","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0045","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1113\/jphysiol.2013.252197","article-title":"Striatal neurones have a specific ability to respond to phasic dopamine release","volume":"591","author":"Castro","year":"2013","journal-title":"J. Physiol. Lond."},{"key":"10.1016\/j.nbd.2019.104506_bb0050","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.neuron.2013.10.041","article-title":"Dopamine D2 receptors regulate the anatomical and functional balance of basal ganglia circuitry","volume":"81","author":"Cazorla","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2019.104506_bb0055","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1002\/mds.26282","article-title":"Balancing the basal ganglia circuitry: a possible new role for dopamine D2 receptors in health and disease","volume":"30","author":"Cazorla","year":"2015","journal-title":"Mov. Disord."},{"key":"10.1016\/j.nbd.2019.104506_bb0060","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.nlm.2013.06.013","article-title":"Molecular and cellular mechanisms of dopamine-mediated behavioral plasticity in the striatum","volume":"105","author":"Cerovic","year":"2013","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.nbd.2019.104506_bb0065","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/nature12354","article-title":"Ultrasensitive fluorescent proteins for imaging neuronal activity","volume":"499","author":"Chen","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2019.104506_bb0070","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1046\/j.1460-9568.2002.01938.x","article-title":"Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging","volume":"15","author":"Cicchetti","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0075","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1046\/j.1471-4159.2001.00201.x","article-title":"Galpha(olf) is necessary for coupling D1 and A2a receptors to adenylyl cyclase in the striatum","volume":"76","author":"Corvol","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2019.104506_bb0080","doi-asserted-by":"crossref","first-page":"7007","DOI":"10.1523\/JNEUROSCI.0676-04.2004","article-title":"Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease","volume":"24","author":"Corvol","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0085","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1038\/sj.npp.1301230","article-title":"Quantitative changes in Galphaolf protein levels, but not D1 receptor, alter specifically acute responses to psychostimulants","volume":"32","author":"Corvol","year":"2007","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.nbd.2019.104506_bb0090","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.biopsych.2009.04.025","article-title":"Genetic inactivation of dopamine D1 but not D2 receptors inhibits L-DOPA-induced dyskinesia and histone activation","volume":"66","author":"Darmopil","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2019.104506_bb0095","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0166-2236(90)90110-V","article-title":"Primate models of movement disorders of basal ganglia origin","volume":"13","author":"DeLong","year":"1990","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0100","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/nn.2286","article-title":"D2R striatopallidal neurons inhibit both locomotor and drug reward processes","volume":"12","author":"Durieux","year":"2009","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0105","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1601-183X.2006.00209.x","article-title":"Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1B-DARPP32 double-knockout mice","volume":"5","author":"Ehrman","year":"2006","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.nbd.2019.104506_bb0110","doi-asserted-by":"crossref","first-page":"5686","DOI":"10.1523\/JNEUROSCI.0492-15.2016","article-title":"Loss of homeostasis in the direct pathway in a mouse model of asymptomatic Parkinson's disease","volume":"36","author":"Escande","year":"2016","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0115","doi-asserted-by":"crossref","first-page":"4728","DOI":"10.1523\/JNEUROSCI.2702-13.2014","article-title":"Mechanisms of dopamine D1 receptor-mediated ERK1\/2 activation in the parkinsonian striatum and their modulation by metabotropic glutamate receptor type 5","volume":"34","author":"Fieblinger","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0120","doi-asserted-by":"crossref","first-page":"5316","DOI":"10.1038\/ncomms6316","article-title":"Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia","volume":"5","author":"Fieblinger","year":"2014","journal-title":"Nat. Commun."},{"issue":"rs12","key":"10.1016\/j.nbd.2019.104506_bb0125","article-title":"A versatile toolkit to produce sensitive FRET biosensors to visualize signaling in time and space","volume":"6","author":"Fritz","year":"2013","journal-title":"Sci. Signal."},{"key":"10.1016\/j.nbd.2019.104506_bb0130","doi-asserted-by":"crossref","first-page":"41432","DOI":"10.1038\/srep41432","article-title":"Striatal neurons expressing D1 and D2 receptors are morphologically distinct and differently affected by dopamine denervation in mice","volume":"7","author":"Gagnon","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2019.104506_bb0135","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1146\/annurev-neuro-061010-113641","article-title":"Modulation of striatal projection systems by dopamine","volume":"34","author":"Gerfen","year":"2011","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0140","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1126\/science.2147780","article-title":"D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons","volume":"250","author":"Gerfen","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.nbd.2019.104506_bb0145","doi-asserted-by":"crossref","first-page":"5042","DOI":"10.1523\/JNEUROSCI.22-12-05042.2002","article-title":"D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1\/2\/MAP kinase","volume":"22","author":"Gerfen","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0150","doi-asserted-by":"crossref","first-page":"10814","DOI":"10.1523\/JNEUROSCI.2660-08.2008","article-title":"Dichotomous anatomical properties of adult striatal medium spiny neurons","volume":"28","author":"Gertler","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0155","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1523\/JNEUROSCI.5352-06.2007","article-title":"Dynamics of protein kinase A signaling at the membrane, in the cytosol, and in the nucleus of neurons in mouse brain slices","volume":"27","author":"Gervasi","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0160","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.neuron.2010.01.014","article-title":"PKA dynamics in a Drosophila learning center: coincidence detection by rutabaga adenylyl cyclase and spatial regulation by dunce phosphodiesterase","volume":"65","author":"Gervasi","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2019.104506_bb0165","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/j.1460-9568.2008.06387.x","article-title":"Lowered cAMP and cGMP signalling in the brain during levodopa-induced dyskinesias in hemiparkinsonian rats: new aspects in the pathogenetic mechanisms","volume":"28","author":"Giorgi","year":"2008","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0170","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/978-3-7091-0932-8_18","article-title":"Integrating neurotransmission in striatal medium spiny neurons","volume":"970","author":"Girault","year":"2012","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.nbd.2019.104506_bb0175","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1073\/pnas.86.7.2493","article-title":"Striatal phosphoproteins in Parkinson disease and progressive supranuclear palsy","volume":"86","author":"Girault","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2019.104506_bb0180","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.coph.2006.08.012","article-title":"ERK2: a logical AND gate critical for drug-induced plasticity?","volume":"7","author":"Girault","year":"2007","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.nbd.2019.104506_bb0185","doi-asserted-by":"crossref","first-page":"9817","DOI":"10.1523\/JNEUROSCI.2707-07.2007","article-title":"Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs","volume":"27","author":"Gong","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0190","doi-asserted-by":"crossref","first-page":"19264","DOI":"10.1073\/pnas.0804598105","article-title":"A genetically encoded fluorescent sensor of ERK activity","volume":"105","author":"Harvey","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2019.104506_bb0195","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.neubiorev.2018.02.007","article-title":"Phosphodiesterase inhibition and modulation of corticostriatal and hippocampal circuits: clinical overview and translational considerations","volume":"87","author":"Heckman","year":"2018","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.nbd.2019.104506_bb0200","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3389\/fnana.2011.00048","article-title":"Identification of a specific assembly of the g protein golf as a critical and regulated module of dopamine and adenosine-activated cAMP pathways in the striatum","volume":"5","author":"Herv\u00e9","year":"2011","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.nbd.2019.104506_bb0205","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1523\/JNEUROSCI.13-05-02237.1993","article-title":"G(olf) and Gs in rat basal ganglia: possible involvement of G(olf) in the coupling of dopamine D1 receptor with adenylyl cyclase","volume":"13","author":"Herv\u00e9","year":"1993","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0210","doi-asserted-by":"crossref","first-page":"4390","DOI":"10.1523\/JNEUROSCI.21-12-04390.2001","article-title":"Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum","volume":"21","author":"Herv\u00e9","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0215","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0169-328X(01)00022-5","article-title":"Dopamine D(1) receptor expression in human basal ganglia and changes in Parkinson's disease","volume":"87","author":"Hurley","year":"2001","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.nbd.2019.104506_bb0220","doi-asserted-by":"crossref","first-page":"8102","DOI":"10.1523\/JNEUROSCI.0473-17.2017","article-title":"ERK\/MAPK signaling is required for pathway-specific striatal motor functions","volume":"37","author":"Hutton","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0225","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0014-5793(04)00333-3","article-title":"Disruption of type 5 adenylyl cyclase negates the developmental increase in Galphaolf expression in the striatum","volume":"564","author":"Iwamoto","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.nbd.2019.104506_bb0230","doi-asserted-by":"crossref","first-page":"11326","DOI":"10.1523\/JNEUROSCI.1380-10.2010","article-title":"Dynamics of the Parkinsonian striatal microcircuit: entrainment into a dominant network state","volume":"30","author":"J\u00e1idar","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0235","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1152\/jn.1989.62.5.1052","article-title":"Intracellular recording of identified neostriatal patch and matrix spiny cells in a slice preparation preserving cortical inputs","volume":"62","author":"Kawaguchi","year":"1989","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.nbd.2019.104506_bb0240","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.expneurol.2013.01.019","article-title":"Alternative splicing of AMPA receptor subunits in the 6-OHDA-lesioned rat model of Parkinson's disease and L-DOPA-induced dyskinesia","volume":"247","author":"Kobylecki","year":"2013","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2019.104506_bb0245","doi-asserted-by":"crossref","first-page":"4647","DOI":"10.1091\/mbc.e11-01-0072","article-title":"Development of an optimized backbone of FRET biosensors for kinases and GTPases","volume":"22","author":"Komatsu","year":"2011","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.nbd.2019.104506_bb0250","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/nature09159","article-title":"Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry","volume":"466","author":"Kravitz","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2019.104506_bb0255","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.nlm.2016.08.006","article-title":"Dendritic diameter influences the rate and magnitude of hippocampal cAMP and PKA transients during \u03b2-adrenergic receptor activation","volume":"138","author":"Luczak","year":"2017","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.nbd.2019.104506_bb0260","doi-asserted-by":"crossref","first-page":"3875","DOI":"10.1523\/JNEUROSCI.4439-05.2006","article-title":"Cortical inputs and GABA interneurons imbalance projection neurons in the striatum of parkinsonian rats","volume":"26","author":"Mallet","year":"2006","journal-title":"J. Neurosci."},{"issue":"Pt A","key":"10.1016\/j.nbd.2019.104506_bb0265","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.neuropharm.2013.08.010","article-title":"Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions","volume":"76","author":"Mango","year":"2014","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.nbd.2019.104506_bb0270","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0004770","article-title":"Striatal medium-sized spiny neurons: identification by nuclear staining and study of neuronal subpopulations in BAC transgenic mice","volume":"4","author":"Matamales","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.nbd.2019.104506_bb0275","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.celrep.2015.09.034","article-title":"Striatal cholinergic interneurons control motor behavior and basal ganglia function in experimental parkinsonism","volume":"13","author":"Maurice","year":"2015","journal-title":"Cell Rep."},{"key":"10.1016\/j.nbd.2019.104506_bb0280","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3389\/fncel.2017.00026","article-title":"Dopamine-induced changes in G\u03b1olf protein levels in Striatonigral and Striatopallidal medium spiny neurons underlie the genesis of l-DOPA-induced dyskinesia in parkinsonian mice","volume":"11","author":"Morigaki","year":"2017","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0285","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.1093\/brain\/awv219","article-title":"Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinsons disease","volume":"138","author":"Niccolini","year":"2015","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2019.104506_bb0290","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1212\/WNL.0000000000004201","article-title":"Loss of phosphodiesterase 4 in Parkinson disease: relevance to cognitive deficits","volume":"89","author":"Niccolini","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.nbd.2019.104506_bb0295","doi-asserted-by":"crossref","first-page":"10460","DOI":"10.1523\/JNEUROSCI.2518-08.2008","article-title":"Distinct roles of PDE4 and PDE10A in the regulation of cAMP\/PKA signaling in the striatum","volume":"28","author":"Nishi","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0300","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/S1471-1931(00)00022-7","article-title":"Organization of the basal ganglia: the importance of axonal collateralization","volume":"23","author":"Parent","year":"2000","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0305","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.biopsych.2005.05.044","article-title":"ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice","volume":"59","author":"Pav\u00f3n","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2019.104506_bb0310","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0060-15.2015","article-title":"Selective effects of PDE10A inhibitors on Striatopallidal neurons require phosphatase inhibition by DARPP-32","volume":"2","author":"Polito","year":"2015","journal-title":"ENeuro"},{"key":"10.1016\/j.nbd.2019.104506_bb0315","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.nbd.2010.08.018","article-title":"L-DOPA-induced dyskinesia in hemiparkinsonian rats is associated with up-regulation of adenylyl cyclase type V\/VI and increased GABA release in the substantia nigra reticulata","volume":"41","author":"Rangel-Barajas","year":"2011","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2019.104506_bb0320","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1038\/nrn2915","article-title":"Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease","volume":"11","author":"Redgrave","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0325","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/mds.26197","article-title":"Dopaminergic regulation of olfactory type G-protein \u03b1 subunit expression in the striatum","volume":"30","author":"Ruiz-DeDiego","year":"2015","journal-title":"Mov. Disord."},{"key":"10.1016\/j.nbd.2019.104506_bb0330","doi-asserted-by":"crossref","first-page":"3438","DOI":"10.1016\/j.celrep.2018.05.059","article-title":"Aberrant striatal activity in parkinsonism and levodopa-induced dyskinesia","volume":"23","author":"Ryan","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.nbd.2019.104506_bb0335","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1111\/j.1460-9568.2004.03566.x","article-title":"Down-regulation of nitrergic transmission in the rat striatum after chronic nigrostriatal deafferentation","volume":"20","author":"Sancesario","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0340","doi-asserted-by":"crossref","first-page":"6995","DOI":"10.1523\/JNEUROSCI.0852-07.2007","article-title":"Critical involvement of cAMP\/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia","volume":"27","author":"Santini","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0345","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1523\/JNEUROSCI.13-03-01080.1993","article-title":"Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons","volume":"13","author":"Schiffmann","year":"1993","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0350","doi-asserted-by":"crossref","first-page":"8814","DOI":"10.1523\/JNEUROSCI.18-21-08814.1998","article-title":"Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation","volume":"18","author":"Sgambato","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0355","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1523\/JNEUROSCI.1778-09.2010","article-title":"Acquisition and performance of goal-directed instrumental actions depends on ERK signaling in distinct regions of dorsal striatum in rats","volume":"30","author":"Shiflett","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0360","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.biopsych.2013.05.006","article-title":"L-DOPA treatment selectively restores spine density in dopamine receptor D2-expressing projection neurons in dyskinetic mice","volume":"75","author":"Su\u00e1rez","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2019.104506_bb0365","doi-asserted-by":"crossref","first-page":"4253","DOI":"10.1093\/cercor\/bhw263","article-title":"L-DOPA oppositely regulates synaptic strength and spine morphology in D1 and D2 striatal projection neurons in dyskinesia","volume":"26","author":"Suarez","year":"2016","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.nbd.2019.104506_bb0370","doi-asserted-by":"crossref","first-page":"3619","DOI":"10.1523\/JNEUROSCI.3184-17.2018","article-title":"Differential synaptic remodeling by dopamine in direct and indirect striatal projection neurons in pitx3\/ mice, a genetic model of Parkinson's disease","volume":"38","author":"Suarez","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0375","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.2002983","article-title":"The temporal pattern of stimulation determines the extent and duration of MAPK activation in a Caenorhabditis elegans sensory neuron","volume":"5","author":"Tomida","year":"2012","journal-title":"Sci. Signal"},{"key":"10.1016\/j.nbd.2019.104506_bb0380","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.celrep.2015.10.009","article-title":"Coordinated regulation of synaptic plasticity at striatopallidal and striatonigral neurons orchestrates motor control","volume":"13","author":"Trusel","year":"2015","journal-title":"Cell Rep."},{"key":"10.1016\/j.nbd.2019.104506_bb0385","doi-asserted-by":"crossref","first-page":"8701","DOI":"10.1523\/JNEUROSCI.20-23-08701.2000","article-title":"Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties","volume":"20","author":"Valjent","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0390","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.tins.2009.06.005","article-title":"Looking BAC at striatal signaling: cell-specific analysis in new transgenic mice","volume":"32","author":"Valjent","year":"2009","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0395","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.biopsych.2006.11.032","article-title":"Spatiotemporal pattern of striatal ERK1\/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors","volume":"62","author":"Westin","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2019.104506_bb0400","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1111\/ejn.13711","article-title":"Inflammation alters AMPA-stimulated calcium responses in dorsal striatal D2 but not D1 spiny projection neurons","volume":"46","author":"Winland","year":"2017","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2019.104506_bb0405","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.expneurol.2007.02.010","article-title":"Attenuation of MPTP neurotoxicity by rolipram, a specific inhibitor of phosphodiesterase IV","volume":"211","author":"Yang","year":"2008","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2019.104506_bb0410","doi-asserted-by":"crossref","first-page":"7451","DOI":"10.1113\/JP274475","article-title":"Detection of phasic dopamine by D1 and D2 striatal medium spiny neurons","volume":"595","author":"Yapo","year":"2017","journal-title":"J. Physiol. Lond."},{"key":"10.1016\/j.nbd.2019.104506_bb0415","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1126\/science.1245622","article-title":"Long-distance integration of nuclear ERK signaling triggered by activation of a few dendritic spines","volume":"342","author":"Zhai","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.nbd.2019.104506_bb0420","doi-asserted-by":"crossref","first-page":"RC91","DOI":"10.1523\/JNEUROSCI.20-16-j0001.2000","article-title":"G(olf)alpha mediates dopamine D1 receptor signaling","volume":"20","author":"Zhuang","year":"2000","journal-title":"J. Neurosci."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996119301664?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996119301664?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:20:00Z","timestamp":1760851200000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996119301664"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":84,"alternative-id":["S0969996119301664"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2019.104506","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential enhancement of ERK, PKA and Ca2+ signaling in direct and indirect striatal neurons of Parkinsonian mice","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2019.104506","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104506"}}