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A."},{"key":"10.1016\/j.nbd.2021.105596_bb0395","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1210\/endo.138.3.4979","article-title":"Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta","volume":"138","author":"Kuiper","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.nbd.2021.105596_bb0400","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3389\/fendo.2020.00385","article-title":"G protein-coupled estrogen receptor: rapid effects on hippocampal-dependent spatial memory and synaptic plasticity","volume":"11","author":"Kumar","year":"2020","journal-title":"Front Endocrinol. 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Rev."},{"key":"10.1016\/j.nbd.2021.105596_bb0480","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1186\/s12974-020-01998-9","article-title":"The peri-menopause in a woman\u2019s life: a systemic inflammatory phase that enables later neurodegenerative disease","volume":"17","author":"McCarthy","year":"2020","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.nbd.2021.105596_bb0485","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.neuron.2007.04.019","article-title":"Timing is everything: making neurons versus glia in the developing cortex","volume":"54","author":"Miller","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2021.105596_bb0490","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/nrn2738","article-title":"TrkB signalling pathways in LTP and learning","volume":"10","author":"Minichiello","year":"2009","journal-title":"Nat. Rev. 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Aging"},{"key":"10.1016\/j.nbd.2021.105596_bb0540","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.expneurol.2004.01.014","article-title":"Impact of the selective estrogen receptor modulator, tamoxifen, on neuronal outgrowth and survival following toxic insults associated with aging and Alzheimer\u2019s disease","volume":"188","author":"O\u2019Neill","year":"2004","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2021.105596_bb0545","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0169-328X(97)00351-3","article-title":"Differential distribution and regulation of estrogen receptor-alpha and -beta mRNA within the female rat brain","volume":"54","author":"Osterlund","year":"1998","journal-title":"Brain Res. Mol. 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A."},{"key":"10.1016\/j.nbd.2021.105596_bb0595","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3389\/fneur.2016.00143","article-title":"Negative role of the environmental endocrine disruptors in the human neurodevelopment","volume":"7","author":"Roncati","year":"2016","journal-title":"Front. Neurol."},{"key":"10.1016\/j.nbd.2021.105596_bb0600","article-title":"Estrogen-like endocrine disrupting chemicals affecting puberty in humans--a review","volume":"15","author":"Roy","year":"2009","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.nbd.2021.105596_bb0605","doi-asserted-by":"crossref","DOI":"10.1289\/EHP5570","article-title":"Environmentally relevant perinatal exposures to Bisphenol A disrupt postnatal Kiss1\/NKB neuronal maturation and puberty onset in female mice","volume":"127","author":"Ruiz-Pino","year":"2019","journal-title":"Environ. 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Sci."},{"key":"10.1016\/j.nbd.2021.105596_bb0615","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.cell.2011.03.050","article-title":"An ADIOL-ERbeta-CtBP transrepression pathway negatively regulates microglia-mediated inflammation","volume":"145","author":"Saijo","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2021.105596_bb0620","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1289\/ehp.6126","article-title":"Effects of polychlorinated biphenyls on estrogen receptor-beta expression in the anteroventral periventricular nucleus","volume":"111","author":"Salama","year":"2003","journal-title":"Environ. 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