{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T09:59:23Z","timestamp":1771581563624,"version":"3.50.1"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T00:00:00Z","timestamp":1656547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.nbd.2022.105811","type":"journal-article","created":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T23:40:12Z","timestamp":1657150812000},"page":"105811","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal regeneration after optic nerve crush in mice"],"prefix":"10.1016","volume":"172","author":[{"given":"Shun","family":"Masuda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroko","family":"Shiraki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Sotomaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kana","family":"Harada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izumi","family":"Hide","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Kiuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norio","family":"Sakai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2022.105811_bb0005","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.expneurol.2015.12.015","article-title":"Reaching the brain: advances in optic nerve regeneration","volume":"287","author":"Benowitz","year":"2017","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2022.105811_bb0010","doi-asserted-by":"crossref","first-page":"5466","DOI":"10.1523\/JNEUROSCI.2752-18.2019","article-title":"Regulation of neuronal survival and axon growth by a perinuclear cAMP compartment","volume":"39","author":"Boczek","year":"2019","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0015","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0306-3623(97)00357-1","article-title":"Free radicals in retinal ischemia","volume":"30","author":"Bonne","year":"1998","journal-title":"Gen. Pharmacol."},{"key":"10.1016\/j.nbd.2022.105811_bb0020","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1523\/JNEUROSCI.4443-07.2008","article-title":"Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma","volume":"28","author":"Buckingham","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0025","doi-asserted-by":"crossref","first-page":"5005","DOI":"10.1167\/iovs.14-14515","article-title":"Nitric oxide (NO): an emerging target for the treatment of glaucoma","volume":"55","author":"Cavet","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2022.105811_bb0030","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1523\/JNEUROSCI.5519-10.2011","article-title":"Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy","volume":"31","author":"Cheng","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0035","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1093\/hmg\/ddq146","article-title":"Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice","volume":"19","author":"Chi","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2022.105811_bb0040","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.nbd.2016.05.002","article-title":"The glial cell modulator ibudilast attenuates neuroinflammation and enhances retinal ganglion cell viability in glaucoma through protein kinase a signaling","volume":"93","author":"Cueva Vargas","year":"2016","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2022.105811_bb0045","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S1044-7431(02)00037-4","article-title":"Intraocular elevation of cyclic AMP potentiates ciliary neurotrophic factor-induced regeneration of adult rat retinal ganglion cell axons","volume":"22","author":"Cui","year":"2003","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0050","doi-asserted-by":"crossref","first-page":"5151","DOI":"10.1167\/iovs.02-1101","article-title":"Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA\/2NNia glaucomatous mice: comparison with RGC loss in aging C57\/BL6 mice","volume":"44","author":"Danias","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2022.105811_bb0055","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s00441-013-1761-0","article-title":"PAC1-expressing structures of neural retina alter their PAC1 isoform splicing during postnatal development","volume":"355","author":"D\u00e9nes","year":"2014","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.nbd.2022.105811_bb0060","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.neuron.2015.02.017","article-title":"Subtype-specific regeneration of retinal ganglion cells following axotomy: effects of osteopontin and mTOR signaling","volume":"85","author":"Duan","year":"2015","journal-title":"Neuron."},{"issue":"Pt 3","key":"10.1016\/j.nbd.2022.105811_bb0065","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1042\/bj3090837","article-title":"Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase","volume":"309","author":"Eggerickx","year":"1995","journal-title":"Biochem. J."},{"key":"10.1016\/j.nbd.2022.105811_bb0070","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/(SICI)1097-4695(199810)37:1<171::AID-NEU13>3.0.CO;2-H","article-title":"Ca2+ channel-regulated neuronal gene expression","volume":"37","author":"Finkbeiner","year":"1998","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.nbd.2022.105811_bb0075","doi-asserted-by":"crossref","first-page":"5507","DOI":"10.1113\/JP273648","article-title":"General features of inhibition in the inner retina","volume":"595","author":"Franke","year":"2017","journal-title":"J. Physiol."},{"key":"10.1016\/j.nbd.2022.105811_bb0080","doi-asserted-by":"crossref","first-page":"11770","DOI":"10.1523\/JNEUROSCI.23-37-11770.2003","article-title":"Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase","volume":"23","author":"Gao","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0085","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1167\/iovs.12-11256","article-title":"Reduction in blood glutathione levels occurs similarly in patients with primary-open angle or normal tension glaucoma","volume":"54","author":"Gherghel","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2022.105811_bb0090","doi-asserted-by":"crossref","first-page":"4299","DOI":"10.1016\/j.cell.2021.06.031","article-title":"Preservation of vision after CaMKII-mediated protection of retinal ganglion cells","volume":"184","author":"Guo","year":"2021","journal-title":"Cell."},{"key":"10.1016\/j.nbd.2022.105811_bb0095","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1016\/j.bbadis.2014.05.026","article-title":"BDNF impairment is associated with age-related changes in the inner retina and exacerbates experimental glaucoma","volume":"1842","author":"Gupta","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.nbd.2022.105811_bb0100","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0304-3940(00)01444-0","article-title":"N-acetylated-alpha-linked-acidic dipeptidase inhibitor has a neuroprotective effect on mouse retinal ganglion cells after pressure-induced ischemia","volume":"292","author":"Harada","year":"2000","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2022.105811_bb0105","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1172\/JCI30178","article-title":"The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma","volume":"117","author":"Harada","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2022.105811_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.147166","article-title":"Detailed neuronal distribution of GPR3 and its co-expression with EF-hand calcium-binding proteins in the mouse central nervous system","volume":"1750","author":"Ikawa","year":"2021","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2022.105811_bb0115","doi-asserted-by":"crossref","first-page":"6382","DOI":"10.1038\/srep06382","article-title":"Simple knockout by electroporation of engineered endonucleases into intact rat embryos","volume":"4","author":"Kaneko","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2022.105811_bb0120","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/nn840","article-title":"A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth","volume":"5","author":"Kao","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneumeth.2020.108914","article-title":"Efficient whole brain transduction by systemic infusion of minimally purified AAV-PHP.eB","volume":"346","author":"Konno","year":"2020","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.nbd.2022.105811_bb0130","doi-asserted-by":"crossref","first-page":"15654","DOI":"10.1523\/JNEUROSCI.4340-10.2010","article-title":"Long-distance axon regeneration in the mature optic nerve: contributions of oncomodulin, cAMP, and pten gene deletion","volume":"30","author":"Kurimoto","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0135","doi-asserted-by":"crossref","first-page":"14816","DOI":"10.1523\/JNEUROSCI.5511-12.2013","article-title":"Neutrophils express oncomodulin and promote optic nerve regeneration","volume":"33","author":"Kurimoto","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0140","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.875662","article-title":"Brain-derived neurotrophic factor-mediated neuroprotection in glaucoma: a review of current state of the art","volume":"13","author":"Lambuk","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.nbd.2022.105811_bb0145","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1186\/s12974-021-02263-3","article-title":"1\u03b1,25-dihydroxyvitamin D(3) protects retinal ganglion cells in glaucomatous mice","volume":"18","author":"Lazzara","year":"2021","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.nbd.2022.105811_bb0150","doi-asserted-by":"crossref","first-page":"7830","DOI":"10.1523\/JNEUROSCI.23-21-07830.2003","article-title":"Axon regeneration in goldfish and rat retinal ganglion cells: differential responsiveness to carbohydrates and cAMP","volume":"23","author":"Li","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0155","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/nbt.2661","article-title":"Heritable gene targeting in the mouse and rat using a CRISPR-Cas system","volume":"31","author":"Li","year":"2013","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.nbd.2022.105811_bb0160","doi-asserted-by":"crossref","first-page":"2866","DOI":"10.1073\/pnas.1721033115","article-title":"Human aging and disease: lessons from age-related macular degeneration","volume":"115","author":"Luu","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2022.105811_bb0165","doi-asserted-by":"crossref","first-page":"204","DOI":"10.4103\/2008-322X.183914","article-title":"Update on normal tension glaucoma","volume":"11","author":"Mallick","year":"2016","journal-title":"J. Ophthalmic Vis. Res."},{"key":"10.1016\/j.nbd.2022.105811_bb0170","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1126\/science.1103974","article-title":"The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes","volume":"306","author":"Mehlmann","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.nbd.2022.105811_bb0175","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0896-6273(00)80586-3","article-title":"Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons","volume":"21","author":"Meyer-Franke","year":"1998","journal-title":"Neuron."},{"key":"10.1016\/j.nbd.2022.105811_bb0180","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1093\/brain\/awm257","article-title":"Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation","volume":"130","author":"M\u00fcller","year":"2007","journal-title":"Brain."},{"key":"10.1016\/j.nbd.2022.105811_bb0185","doi-asserted-by":"crossref","first-page":"10806","DOI":"10.1523\/JNEUROSCI.3532-04.2004","article-title":"Cellular mechanisms associated with spontaneous and ciliary neurotrophic factor-cAMP-induced survival and axonal regeneration of adult retinal ganglion cells","volume":"24","author":"Park","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0190","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1126\/science.1161566","article-title":"Promoting axon regeneration in the adult CNS by modulation of the PTEN\/mTOR pathway","volume":"322","author":"Park","year":"2008","journal-title":"Science."},{"key":"10.1016\/j.nbd.2022.105811_bb0195","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.mcn.2009.04.002","article-title":"Cytokine-induced SOCS expression is inhibited by cAMP analogue: impact on regeneration in injured retina","volume":"41","author":"Park","year":"2009","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0200","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.brainresbull.2019.05.006","article-title":"Potential role of P2X7 receptor in neurodegenerative processes in a murine model of glaucoma","volume":"150","author":"P\u00e9rez de Lara","year":"2019","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.nbd.2022.105811_bb0205","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1093\/brain\/awl015","article-title":"Synergistic action of brain-derived neurotrophic factor and lens injury promotes retinal ganglion cell survival, but leads to optic nerve dystrophy in vivo","volume":"129","author":"Pernet","year":"2006","journal-title":"Brain."},{"key":"10.1016\/j.nbd.2022.105811_bb0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2022.114942","article-title":"The P2X7 receptor as a new pharmacological target for retinal diseases","volume":"198","author":"Platania","year":"2022","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.nbd.2022.105811_bb0215","article-title":"Ocular blood flow and cerebrospinal fluid pressure in glaucoma","volume":"5","author":"Promelle","year":"2016","journal-title":"Acta Radiol. Open"},{"key":"10.1016\/j.nbd.2022.105811_bb0220","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/S0140-6736(10)61423-7","article-title":"Glaucoma","volume":"377","author":"Quigley","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2022.105811_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2020.114199","article-title":"P2X7 receptor antagonism preserves retinal ganglion cells in glaucomatous mice","volume":"180","author":"Romano","year":"2020","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.nbd.2022.105811_bb0230","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0014-5793(93)80828-I","article-title":"Molecular cloning of a novel putative G protein-coupled receptor (GPCR21) which is expressed predominantly in mouse central nervous system","volume":"336","author":"Saeki","year":"1993","journal-title":"FEBS Lett."},{"key":"10.1016\/j.nbd.2022.105811_bb0235","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.nbd.2022.105811_bb0240","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0079-6123(08)01134-5","article-title":"Targeting excitotoxic\/free radical signaling pathways for therapeutic intervention in glaucoma","volume":"173","author":"Seki","year":"2008","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.nbd.2022.105811_bb0245","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0304-3940(97)00869-0","article-title":"Distribution and ultrastructural localization of a receptor for pituitary adenylate cyclase activating polypeptide and its mRNA in the rat retina","volume":"238","author":"Seki","year":"1997","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2022.105811_bb0250","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s12031-010-9410-5","article-title":"Suppression of rat retinal ganglion cell death by PACAP following transient ischemia induced by high intraocular pressure","volume":"43","author":"Seki","year":"2011","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0255","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0896-6273(00)80780-1","article-title":"Retinal ganglion cells lose trophic responsiveness after axotomy","volume":"23","author":"Shen","year":"1999","journal-title":"Neuron."},{"key":"10.1016\/j.nbd.2022.105811_bb0260","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.jphs.2022.01.005","article-title":"Potential role of inducible GPR3 expression under stimulated T cell conditions","volume":"148","author":"Shiraki","year":"2022","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.nbd.2022.105811_bb0265","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/j.bbadis.2014.07.012","article-title":"The role of soluble adenylyl cyclase in neurite outgrowth","volume":"1842","author":"Stiles","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.nbd.2022.105811_bb0270","doi-asserted-by":"crossref","first-page":"3502","DOI":"10.1016\/j.cell.2021.04.037","article-title":"Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis","volume":"184","author":"Sveidahl Johansen","year":"2021","journal-title":"Cell."},{"key":"10.1016\/j.nbd.2022.105811_bb0275","doi-asserted-by":"crossref","first-page":"10506","DOI":"10.1074\/jbc.M700911200","article-title":"Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowth","volume":"282","author":"Tanaka","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2022.105811_bb0280","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0005922","article-title":"The Gs-linked receptor GPR3 inhibits the proliferation of cerebellar granule cells during postnatal development","volume":"4","author":"Tanaka","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2022.105811_bb0285","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.nbd.2014.04.007","article-title":"Developmental expression of GPR3 in rodent cerebellar granule neurons is associated with cell survival and protects neurons from various apoptotic stimuli","volume":"68","author":"Tanaka","year":"2014","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2022.105811_bb0290","article-title":"GPR3 accelerates neurite outgrowth and neuronal polarity formation via PI3 kinase-mediating signaling pathway in cultured primary neurons","volume":"103691","author":"Tanaka","year":"2021","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0295","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0896-6273(00)81010-7","article-title":"Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism","volume":"20","author":"Tao","year":"1998","journal-title":"Neuron."},{"key":"10.1016\/j.nbd.2022.105811_bb0300","first-page":"563","article-title":"Normal-tension glaucoma: pathogenesis and genetics","volume":"17","author":"Trivli","year":"2019","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.nbd.2022.105811_bb0305","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1111\/ceo.12992","article-title":"DBA\/2J mouse model for experimental glaucoma: pitfalls and problems","volume":"45","author":"Turner","year":"2017","journal-title":"Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.nbd.2022.105811_bb0310","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2021.105524","article-title":"Targeted deletion of PAC1 receptors in retinal neurons enhances neuron loss and axonopathy in a model of multiple sclerosis and optic neuritis","volume":"160","author":"Van","year":"2021","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2022.105811_bb0315","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1001\/jama.2014.3192","article-title":"The pathophysiology and treatment of glaucoma: a review","volume":"311","author":"Weinreb","year":"2014","journal-title":"Jama."},{"key":"10.1016\/j.nbd.2022.105811_bb0320","first-page":"284","article-title":"Prevalence of myocilin and optineurin sequence variants in German normal tension glaucoma patients","volume":"11","author":"Weisschuh","year":"2005","journal-title":"Mol. Vis."},{"key":"10.1016\/j.nbd.2022.105811_bb0325","first-page":"724","article-title":"Variations in the WDR36 gene in German patients with normal tension glaucoma","volume":"13","author":"Weisschuh","year":"2007","journal-title":"Mol. Vis."},{"key":"10.1016\/j.nbd.2022.105811_bb0330","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2017282118","article-title":"Chemokine CCL5 promotes robust optic nerve regeneration and mediates many of the effects of CNTF gene therapy","volume":"118","author":"Xie","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2022.105811_bb0335","doi-asserted-by":"crossref","first-page":"R628","DOI":"10.1016\/j.cub.2016.05.025","article-title":"Common and divergent mechanisms in developmental neuronal remodeling and dying back neurodegeneration","volume":"26","author":"Yaron","year":"2016","journal-title":"Curr. Biol."},{"key":"10.1016\/j.nbd.2022.105811_bb0340","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s12031-019-01309-9","article-title":"PACAP attenuates optic nerve crush-induced retinal ganglion cell apoptosis via activation of the CREB-Bcl-2 pathway","volume":"68","author":"Ye","year":"2019","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0345","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/nn1701","article-title":"Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells","volume":"9","author":"Yin","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2022.105811_bb0350","doi-asserted-by":"crossref","first-page":"10431","DOI":"10.1038\/ncomms10431","article-title":"ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes","volume":"7","author":"Yoshimi","year":"2016","journal-title":"Nat. Commun."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996122002030?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996122002030?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:31:51Z","timestamp":1760851911000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996122002030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":70,"alternative-id":["S0969996122002030"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2022.105811","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal regeneration after optic nerve crush in mice","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2022.105811","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"105811"}}