{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T01:00:57Z","timestamp":1789520457981,"version":"build-2803163510"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.nbd.2022.105880","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T13:47:55Z","timestamp":1664545675000},"page":"105880","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities"],"prefix":"10.1016","volume":"174","author":[{"given":"Yuriko","family":"Katsumata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lincoln M.","family":"Shade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Hohman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose M.","family":"Farfel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter A.","family":"Kukull","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Fardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter T.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2022.105880_bb0005","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/ana.21154","article-title":"TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer\u2019s disease","volume":"61","author":"Amador-Ortiz","year":"2007","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2022.105880_bb0010","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00401-020-02255-2","article-title":"Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-Centre study","volume":"141","author":"Attems","year":"2021","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0015","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3233\/ADR-200177","article-title":"Sorting out the role of the Sortilin-related receptor 1 in Alzheimer\u2019s disease","volume":"4","author":"Barthelson","year":"2020","journal-title":"J. Alzheimers Dis. Rep."},{"key":"10.1016\/j.nbd.2022.105880_bb0020","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/NEN.0b013e31824b211b","article-title":"Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer disease centers, 2005-2010","volume":"71","author":"Beach","year":"2012","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2022.105880_bb0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1004606","article-title":"Genome-wide association meta-analysis of neuropathologic features of Alzheimer\u2019s disease and related dementias","volume":"10","author":"Beecham","year":"2014","journal-title":"PLoS Genet."},{"key":"10.1016\/j.nbd.2022.105880_bb0030","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/s41588-022-01024-z","article-title":"New insights into the genetic etiology of Alzheimer\u2019s disease and related dementias","volume":"54","author":"Bellenguez","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.nbd.2022.105880_bb0035","doi-asserted-by":"crossref","first-page":"S161","DOI":"10.3233\/JAD-179939","article-title":"Religious orders study and rush memory and aging project","volume":"64","author":"Bennett","year":"2018","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.nbd.2022.105880_bb0040","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222413633","article-title":"Investigating the Endo-lysosomal system in major neurocognitive disorders due to Alzheimer\u2019s disease, frontotemporal lobar degeneration and Lewy body disease: evidence for SORL1 as a cross-disease gene","volume":"22","author":"Benussi","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.nbd.2022.105880_bb0045","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/s41467-017-00471-1","article-title":"Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis","volume":"8","author":"Benyamin","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2022.105880_bb0050","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1093\/jnen\/nly049","article-title":"The revised National Alzheimer\u2019s coordinating Center\u2019s neuropathology form-available data and new analyses","volume":"77","author":"Besser","year":"2018","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2022.105880_bb0055","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/ana.25380","article-title":"Attributable risk of Alzheimer\u2019s dementia attributed to age-related neuropathologies","volume":"85","author":"Boyle","year":"2019","journal-title":"Ann. Neurol."},{"issue":"7","key":"10.1016\/j.nbd.2022.105880_bb0060","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1093\/brain\/awab092","article-title":"To what degree is late life cognitive decline driven by age-related neuropathologies?","volume":"144","author":"Boyle","year":"2021","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2022.105880_bb0065","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/BF00305867","article-title":"Alzheimer\u2019s disease affects limbic nuclei of the thalamus","volume":"81","author":"Braak","year":"1991","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0070","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.jalz.2016.09.015","article-title":"Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample","volume":"13","author":"Brenowitz","year":"2017","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.nbd.2022.105880_bb0075","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s00401-019-01991-4","article-title":"SORL1 genetic variants and Alzheimer disease risk: a literature review and meta-analysis of sequencing data","volume":"138","author":"Campion","year":"2019","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0080","doi-asserted-by":"crossref","DOI":"10.3390\/cancers12082197","article-title":"Extracellular glutathione peroxidase GPx3 and its role in Cancer","volume":"12","author":"Chang","year":"2020","journal-title":"Cancers (Basel)."},{"key":"10.1016\/j.nbd.2022.105880_bb0085","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13742-015-0047-8","article-title":"Second-generation PLINK: rising to the challenge of larger and richer datasets","volume":"4","author":"Chang","year":"2015","journal-title":"Gigascience."},{"key":"10.1016\/j.nbd.2022.105880_bb0090","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1016\/j.jalz.2017.09.010","article-title":"Alzheimer\u2019s disease sequencing project discovery and replication criteria for cases and controls: data from a community-based prospective cohort study with autopsy follow-up","volume":"13","author":"Crane","year":"2017","journal-title":"Alzheimers Dement."},{"issue":"5","key":"10.1016\/j.nbd.2022.105880_bb0095","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s00401-022-02416-5","article-title":"Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies","volume":"143","author":"Cykowski","year":"2022","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0100","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/s40478-021-01250-2","article-title":"Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study","volume":"9","author":"Dugan","year":"2021","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.nbd.2022.105880_bb0105","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1212\/WNL.0000000000002909","article-title":"Relation of genomic variants for Alzheimer disease dementia to common neuropathologies","volume":"87","author":"Farfel","year":"2016","journal-title":"Neurology."},{"key":"10.1016\/j.nbd.2022.105880_bb0110","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/jnnp-2016-314411","article-title":"Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer\u2019s and Parkinson\u2019s diseases","volume":"88","author":"Ferrari","year":"2017","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.nbd.2022.105880_bb0115","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1001\/archpsyc.63.2.168","article-title":"Role of genes and environments for explaining Alzheimer disease","volume":"63","author":"Gatz","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.nbd.2022.105880_bb0120","doi-asserted-by":"crossref","first-page":"e1422","DOI":"10.1212\/WNL.0000000000200001","article-title":"Limbic-predominant age-related TDP-43 encephalopathy: medical and pathologic factors associated with comorbid hippocampal sclerosis","volume":"98","author":"Gauthreaux","year":"2022","journal-title":"Neurology."},{"key":"10.1016\/j.nbd.2022.105880_bb0125","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1038\/nature09534","article-title":"A map of human genome variation from population-scale sequencing","volume":"467","author":"Genomes Project","year":"2010","journal-title":"Nature."},{"key":"10.1016\/j.nbd.2022.105880_bb0130","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1159\/000197389","article-title":"Adjustment for selection bias in observational studies with application to the analysis of autopsy data","volume":"32","author":"Haneuse","year":"2009","journal-title":"Neuroepidemiology."},{"key":"10.1016\/j.nbd.2022.105880_bb0135","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jalz.2015.02.012","article-title":"Global and local ancestry in African-Americans: implications for Alzheimer\u2019s disease risk","volume":"12","author":"Hohman","year":"2016","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.nbd.2022.105880_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3233\/JAD-170242","article-title":"Challenges and considerations related to studying dementia in blacks\/African Americans","volume":"60","author":"Ighodaro","year":"2017","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.nbd.2022.105880_bb0145","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nrneurol.2015.251","article-title":"Suspected non-Alzheimer disease pathophysiology--concept and controversy","volume":"12","author":"Jack","year":"2016","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.nbd.2022.105880_bb0150","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1093\/brain\/aww224","article-title":"TDP-43 stage, mixed pathologies, and clinical Alzheimer\u2019s-type dementia","volume":"139","author":"James","year":"2016","journal-title":"Brain."},{"key":"10.1016\/j.nbd.2022.105880_bb0155","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1007\/s00401-015-1407-2","article-title":"PART, a distinct tauopathy, different from classical sporadic Alzheimer disease","volume":"129","author":"Jellinger","year":"2015","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0160","doi-asserted-by":"crossref","DOI":"10.1093\/brain\/awz224","article-title":"LATE to the PART-y","volume":"142","author":"Josephs","year":"2019","journal-title":"Brain."},{"key":"10.1016\/j.nbd.2022.105880_bb0165","doi-asserted-by":"crossref","first-page":"647","DOI":"10.3233\/JAD-210293","article-title":"Four common late-life cognitive trajectories patterns associate with replicable underlying Neuropathologies","volume":"82","author":"Karanth","year":"2021","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.nbd.2022.105880_bb0170","doi-asserted-by":"crossref","first-page":"565","DOI":"10.2174\/138945008784911750","article-title":"WNT signaling in stem cell biology and regenerative medicine","volume":"9","author":"Katoh","year":"2008","journal-title":"Curr. Drug Targets"},{"key":"10.1016\/j.nbd.2022.105880_bb0175","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s00401-020-02211-0","article-title":"Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy","volume":"140","author":"Katsumata","year":"2020","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0180","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.jalz.2018.03.002","article-title":"The National Institute on Aging and the Alzheimer\u2019s Association research framework for Alzheimer\u2019s disease: perspectives from the research roundtable","volume":"14","author":"Knopman","year":"2018","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.nbd.2022.105880_bb0185","first-page":"13","article-title":"Self-reported memory complaints: a comparison of demented and unimpaired outcomes","volume":"3","author":"Kryscio","year":"2016","journal-title":"J. Prev. Alzheimers Dis."},{"key":"10.1016\/j.nbd.2022.105880_bb0190","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/0895-4356(96)00195-3","article-title":"Apolipoprotein E in Alzheimer\u2019s disease risk and case detection: a case-control study","volume":"49","author":"Kukull","year":"1996","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.nbd.2022.105880_bb0195","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/s12916-022-02335-y","article-title":"Shared genetic links between frontotemporal dementia and psychiatric disorders","volume":"20","author":"Li","year":"2022","journal-title":"BMC Med."},{"key":"10.1016\/j.nbd.2022.105880_bb0200","doi-asserted-by":"crossref","first-page":"2423 e7","DOI":"10.1016\/j.neurobiolaging.2014.05.009","article-title":"ABCA7 gene and the risk of Alzheimer\u2019s disease in Han Chinese in Taiwan","volume":"35","author":"Liao","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.nbd.2022.105880_bb0205","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/1471-2350-12-104","article-title":"Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population","volume":"12","author":"Liu","year":"2011","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.nbd.2022.105880_bb0210","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1001\/archneurol.2011.646","article-title":"A comprehensive genetic association study of Alzheimer disease in African Americans","volume":"68","author":"Logue","year":"2011","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.nbd.2022.105880_bb0215","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.1093\/bioinformatics\/btv402","article-title":"LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants","volume":"31","author":"Machiela","year":"2015","journal-title":"Bioinformatics."},{"key":"10.1016\/j.nbd.2022.105880_bb0220","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jalz.2011.03.005","article-title":"The diagnosis of dementia due to Alzheimer\u2019s disease: recommendations from the National Institute on Aging-Alzheimer\u2019s Association workgroups on diagnostic guidelines for Alzheimer\u2019s disease","volume":"7","author":"McKhann","year":"2011","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.nbd.2022.105880_bb0225","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/WCO.0000000000000912","article-title":"What is \u2018Alzheimer\u2019s disease\u2019? The neuropathological heterogeneity of clinically defined Alzheimer\u2019s dementia","volume":"34","author":"Mehta","year":"2021","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.nbd.2022.105880_bb0230","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines10051112","article-title":"Cross-talk between Wnt signaling and Src tyrosine kinase","volume":"10","author":"Min","year":"2022","journal-title":"Biomedicines."},{"key":"10.1016\/j.nbd.2022.105880_bb0235","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.1016\/S0197-4580(97)00058-4","article-title":"The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer\u2019s disease: a commentary","volume":"18","author":"Mirra","year":"1997","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.nbd.2022.105880_bb0240","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1212\/WNL.41.4.479","article-title":"The consortium to establish a registry for Alzheimer\u2019s disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer\u2019s disease","volume":"41","author":"Mirra","year":"1991","journal-title":"Neurology."},{"key":"10.1016\/j.nbd.2022.105880_bb0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00401-011-0910-3","article-title":"National Institute on Aging-Alzheimer\u2019s Association guidelines for the neuropathologic assessment of Alzheimer\u2019s disease: a practical approach","volume":"123","author":"Montine","year":"2012","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0250","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/ajmg.b.32499","article-title":"Genomic variants, genes, and pathways of Alzheimer\u2019s disease: an overview","volume":"174","author":"Naj","year":"2017","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"issue":"4","key":"10.1016\/j.nbd.2022.105880_bb0255","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.ygeno.2018.05.004","article-title":"Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer\u2019s disease sequencing project","volume":"111","author":"Naj","year":"2018","journal-title":"Genomics."},{"key":"10.1016\/j.nbd.2022.105880_bb0260","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/nen.0b013e31815c5efb","article-title":"Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles \u201cdo count\u201d when staging disease severity","volume":"66","author":"Nelson","year":"2007","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2022.105880_bb0265","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1750-3639.2008.00244.x","article-title":"Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons","volume":"20","author":"Nelson","year":"2010","journal-title":"Brain Pathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0270","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1093\/brain\/awr053","article-title":"Hippocampal sclerosis in advanced age: clinical and pathological features","volume":"134","author":"Nelson","year":"2011","journal-title":"Brain."},{"key":"10.1016\/j.nbd.2022.105880_bb0275","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s00401-014-1282-2","article-title":"ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology","volume":"127","author":"Nelson","year":"2014","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0280","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/NEN.0000000000000151","article-title":"Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology","volume":"74","author":"Nelson","year":"2015","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2022.105880_bb0285","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1093\/jnen\/nlw033","article-title":"\u201cnew old pathologies\u201d: AD, PART, and cerebral age-related TDP-43 with sclerosis (CARTS)","volume":"75","author":"Nelson","year":"2016","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2022.105880_bb0290","doi-asserted-by":"crossref","DOI":"10.1093\/brain\/awz099","article-title":"Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report","author":"Nelson","year":"2019","journal-title":"Brain."},{"key":"10.1016\/j.nbd.2022.105880_bb0295","doi-asserted-by":"crossref","DOI":"10.1093\/brain\/awz226","article-title":"Reply: LATE to the PART-y","volume":"142","author":"Nelson","year":"2019","journal-title":"Brain."},{"issue":"1","key":"10.1016\/j.nbd.2022.105880_bb0300","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s00401-022-02444-1","article-title":"Frequency of LATE neuropathologic change across the spectrum of Alzheimer\u2019s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts","volume":"144","author":"Nelson","year":"2022","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2022.105880_bb0305","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neurobiolaging.2015.10.009","article-title":"Brain pathologies in extreme old age","volume":"37","author":"Neltner","year":"2016","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.nbd.2022.105880_bb0310","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1126\/science.1134108","article-title":"Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis","volume":"314","author":"Neumann","year":"2006","journal-title":"Science."},{"key":"10.1016\/j.nbd.2022.105880_bb0315","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/oxfordjournals.aje.a009290","article-title":"Head injury and risk of Alzheimer\u2019s disease by apolipoprotein E genotype","volume":"146","author":"O\u2019Meara","year":"1997","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.nbd.2022.105880_bb0320","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"Purcell","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.nbd.2022.105880_bb0325","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1001\/jama.2013.2973","article-title":"Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E 4,and the risk of late-onset Alzheimer disease in African Americans","volume":"309","author":"Reitz","year":"2013","journal-title":"JAMA."},{"key":"10.1016\/j.nbd.2022.105880_bb0330","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13073-021-01006-6","article-title":"Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3\/TNIP1","volume":"14","author":"Restuadi","year":"2022","journal-title":"Genome Med."},{"key":"10.1016\/j.nbd.2022.105880_bb0335","doi-asserted-by":"crossref","first-page":"3491269","DOI":"10.1155\/2018\/3491269","article-title":"TNIP1 in autoimmune diseases: regulation of toll-like receptor signaling","volume":"2018","author":"Shamilov","year":"2018","journal-title":"J Immunol Res"},{"key":"10.1016\/j.nbd.2022.105880_bb0340","doi-asserted-by":"crossref","first-page":"799","DOI":"10.3233\/JAD-121594","article-title":"Clinicopathologic study of Alzheimer\u2019s disease: Alzheimer mimics","volume":"35","author":"Shim","year":"2013","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.nbd.2022.105880_bb0345","article-title":"Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program","author":"Taliun","year":"2019","journal-title":"bioRxiv"},{"key":"10.1016\/j.nbd.2022.105880_bb0350","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s40478-017-0441-9","article-title":"Identification and description of three families with familial Alzheimer disease that segregate variants in the SORL1 gene","volume":"5","author":"Thonberg","year":"2017","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.nbd.2022.105880_bb0355","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1212\/01.WNL.0000150892.81839.D1","article-title":"Genetic association between the APOE*4 allele and Lewy bodies in Alzheimer disease","volume":"64","author":"Tsuang","year":"2005","journal-title":"Neurology."},{"key":"10.1016\/j.nbd.2022.105880_bb0360","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1093\/brain\/awm021","article-title":"Rates of cerebral atrophy differ in different degenerative pathologies","volume":"130","author":"Whitwell","year":"2007","journal-title":"Brain."},{"key":"10.1016\/j.nbd.2022.105880_bb0365","first-page":"2751","article-title":"Sorting receptor SORLA--a trafficking path to avoid Alzheimer disease","volume":"126","author":"Willnow","year":"2013","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.nbd.2022.105880_bb0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2020.05.010","article-title":"Genetics of gene expression in the aging human brain reveal TDP-43 Proteinopathy pathophysiology","volume":"107","author":"Yang","year":"2020","journal-title":"Neuron."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996122002728?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996122002728?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:34:40Z","timestamp":1760852080000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996122002728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":74,"alternative-id":["S0969996122002728"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2022.105880","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2022.105880","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"105880"}}