{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T04:38:38Z","timestamp":1784003918935,"version":"3.55.0"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,29]],"date-time":"2022-11-29T00:00:00Z","timestamp":1669680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.nbd.2022.105938","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T11:23:15Z","timestamp":1669807395000},"page":"105938","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms"],"prefix":"10.1016","volume":"176","author":[{"given":"Daniel","family":"Felsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismael","family":"Santa-Maria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Ilyas","family":"Cosacak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon","family":"French","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip L.","family":"De Jager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caghan","family":"Kizil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Tosto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2022.105938_bb0005","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2020.611998","article-title":"Dementia research in the Caribbean Hispanic Islands: present findings and future trends","volume":"8","author":"Acosta","year":"2021","journal-title":"Front. Public Health"},{"key":"10.1016\/j.nbd.2022.105938_bb0010","doi-asserted-by":"crossref","DOI":"10.1038\/sdata.2016.89","article-title":"Human whole genome genotype and transcriptome data for Alzheimer\u2019s and other neurodegenerative diseases","volume":"3","author":"Allen","year":"2016","journal-title":"Sci. Data"},{"key":"10.1016\/j.nbd.2022.105938_bb0015","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.jalz.2017.09.012","article-title":"Conserved brain myelination networks are altered in Alzheimer\u2019s and other neurodegenerative diseases","volume":"14","author":"Allen","year":"2018","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.nbd.2022.105938_bb0020","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.nbd.2022.105938_bb0025","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1001\/jama.286.18.2257","article-title":"A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families","volume":"286","author":"Athan","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.nbd.2022.105938_bb0030","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.jalz.2018.09.009","article-title":"Perspectives on ethnic and racial disparities in Alzheimer\u2019s disease and related dementias: update and areas of immediate need","volume":"15","author":"Babulal","year":"2019","journal-title":"Alzheimers Dement. J. Alzheimers Assoc."},{"key":"10.1016\/j.nbd.2022.105938_bb0035","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.neuron.2019.12.015","article-title":"Deep multilayer brain proteomics identifies molecular networks in Alzheimer\u2019s disease progression","volume":"105","author":"Bai","year":"2020","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2022.105938_bb0040","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/s41588-022-01024-z","article-title":"New insights into the genetic etiology of Alzheimer\u2019s disease and related dementias","volume":"54","author":"Bellenguez","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.nbd.2022.105938_bb0045","doi-asserted-by":"crossref","first-page":"S161","DOI":"10.3233\/JAD-179939","article-title":"Religious orders study and rush memory and aging project","volume":"64","author":"Bennett","year":"2018","journal-title":"J. Alzheimers Dis. JAD"},{"key":"10.1016\/j.nbd.2022.105938_bb0050","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3934\/Neuroscience.2021005","article-title":"The biological pathways of Alzheimer disease: a review","volume":"8","author":"Calabr\u00f2","year":"2020","journal-title":"AIMS Neurosci."},{"key":"10.1016\/j.nbd.2022.105938_bb0055","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.celrep.2019.06.073","article-title":"Integrating gene and Protein expression reveals perturbed functional networks in Alzheimer\u2019s disease","volume":"28","author":"Canchi","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.nbd.2022.105938_bb0060","series-title":"org.Hs.eg.db","author":"Carlson","year":"2016"},{"key":"10.1016\/j.nbd.2022.105938_bb0065","series-title":"GO.db","author":"Carlson","year":"2016"},{"key":"10.1016\/j.nbd.2022.105938_bb0070","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.94.15_supplement.4626","article-title":"Transcriptome analysis of single nucleus RNA-seq from Alzheimer disease APOE4 carrier brains in African American (AA) and non-Hispanic whites (NHW) reveals differences in APOE expression (4626)","volume":"94","author":"Celis","year":"2020","journal-title":"Neurology"},{"key":"10.1016\/j.nbd.2022.105938_bb0075","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.neuron.2019.05.013","article-title":"Regional heterogeneity in gene expression, regulation, and coherence in the frontal cortex and Hippocampus across development and schizophrenia","volume":"103","author":"Collado-Torres","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2022.105938_bb0080","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2022.903175","article-title":"Bulk and single-nucleus transcriptomics highlight intra-telencephalic and somatostatin neurons in Alzheimer\u2019s disease","volume":"15","author":"Consens","year":"2022","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.nbd.2022.105938_bb0085","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1038\/s41380-017-0004-2","article-title":"Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia","volume":"24","author":"de Vrij","year":"2019","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.nbd.2022.105938_bb0090","doi-asserted-by":"crossref","first-page":"eaau3333","DOI":"10.1126\/sciadv.aau3333","article-title":"Porphyromonas gingivalis in Alzheimer\u2019s disease brains: evidence for disease causation and treatment with small-molecule inhibitors","volume":"5","author":"Dominy","year":"2019","journal-title":"Sci. Adv."},{"key":"10.1016\/j.nbd.2022.105938_bb0095","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1177\/152692480201200303","article-title":"Hispanic perceptions of organ donation","volume":"12","author":"Frates","year":"2002","journal-title":"Prog. Transplant. Aliso Viejo Calif"},{"key":"10.1016\/j.nbd.2022.105938_bb0100","first-page":"15","article-title":"Altered mechanisms of protein synthesis in frontal cortex in Alzheimer disease and a mouse model","volume":"6","author":"Garcia-Esparcia","year":"2017","journal-title":"Am. J. Neurodegener. Dis."},{"key":"10.1016\/j.nbd.2022.105938_bb0105","article-title":"A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma and includes a genetic link with Alzheimer\u2019s disease","author":"Gharahkhani","year":"2020","journal-title":"bioRxiv"},{"key":"10.1016\/j.nbd.2022.105938_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41398-020-00882-7","article-title":"Alzheimer\u2019s disease-related dysregulation of mRNA translation causes key pathological features with ageing","volume":"10","author":"Ghosh","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.nbd.2022.105938_bb0115","article-title":"Expression quantitative trait loci (eQTL) analysis in a diverse Alzheimer disease cohort reveals ancestry-specific regulatory architectures","volume":"17","author":"Griswold","year":"2021","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.nbd.2022.105938_bb0120","first-page":"459","article-title":"Glaucoma in the English-speaking Caribbean","volume":"60","author":"Grosvenor","year":"2011","journal-title":"West Indian Med. J."},{"key":"10.1016\/j.nbd.2022.105938_bb0125","first-page":"2755","article-title":"Molecular properties underlying regional vulnerability to Alzheimer\u2019s disease pathology","volume":"141","author":"Grothe","year":"2018","journal-title":"Brain J. Neurol."},{"key":"10.1016\/j.nbd.2022.105938_bb0130","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1038\/s41593-019-0539-4","article-title":"A single-cell atlas of entorhinal cortex from individuals with Alzheimer\u2019s disease reveals cell-type-specific gene expression regulation","volume":"22","author":"Grubman","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2022.105938_bb0135","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2022.105938_bb0140","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/bpa.12335","article-title":"Altered machinery of protein synthesis in Alzheimer\u2019s: from the nucleolus to the ribosome","volume":"26","author":"Hern\u00e1ndez-Ortega","year":"2016","journal-title":"Brain Pathol. Zurich Switz."},{"key":"10.1016\/j.nbd.2022.105938_bb0145","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s13195-017-0315-1","article-title":"Race modifies the relationship between cognition and Alzheimer\u2019s disease cerebrospinal fluid biomarkers","volume":"9","author":"Howell","year":"2017","journal-title":"Alzheimers Res. Ther."},{"key":"10.1016\/j.nbd.2022.105938_bb0150","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0204941","article-title":"Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice","volume":"13","author":"Ilievski","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2022.105938_bb0155","doi-asserted-by":"crossref","first-page":"173","DOI":"10.18865\/ed.29.S1.173","article-title":"Defining and achieving health equity in genomic medicine","volume":"29","author":"Jooma","year":"2019","journal-title":"Ethn. Dis."},{"key":"10.1016\/j.nbd.2022.105938_bb0160","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1186\/s12864-017-4039-1","article-title":"The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia","volume":"18","author":"Kumar","year":"2017","journal-title":"BMC Genomics"},{"key":"10.1016\/j.nbd.2022.105938_bb0165","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1001\/jamaneurol.2020.3536","article-title":"Novel Alzheimer disease risk loci and pathways in African American individuals using the African genome resources panel: a meta-analysis","volume":"78","author":"Kunkle","year":"2021","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.nbd.2022.105938_bb0170","series-title":"Multi-Ancestry Meta-Analysis and Fine-Mapping in Alzheimer\u2019s Disease","author":"Lake","year":"2022"},{"key":"10.1016\/j.nbd.2022.105938_bb0175","doi-asserted-by":"crossref","first-page":"R29","DOI":"10.1186\/gb-2014-15-2-r29","article-title":"Voom: precision weights unlock linear model analysis tools for RNA-seq read counts","volume":"15","author":"Law","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.nbd.2022.105938_bb0180","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/s41593-020-00764-7","article-title":"Molecular characterization of selectively vulnerable neurons in Alzheimer\u2019s disease","volume":"24","author":"Leng","year":"2021","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2022.105938_bb0185","first-page":"510420","article-title":"Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach","author":"Logsdon","year":"2019","journal-title":"bioRxiv"},{"key":"10.1016\/j.nbd.2022.105938_bb0190","doi-asserted-by":"crossref","first-page":"9370","DOI":"10.1038\/s41598-018-27627-3","article-title":"Gene expression profiling of periodontitis-affected gingival tissue by spatial transcriptomics","volume":"8","author":"Lundmark","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2022.105938_bb0195","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/s41586-019-1195-2","article-title":"Single-cell transcriptomic analysis of Alzheimer\u2019s disease","volume":"570","author":"Mathys","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2022.105938_bb0200","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003925","article-title":"Reconstructing the population genetic history of the Caribbean","volume":"9","author":"Moreno-Estrada","year":"2013","journal-title":"PLoS Genet."},{"key":"10.1016\/j.nbd.2022.105938_bb0205","first-page":"14","article-title":"Most pathways can be related to the pathogenesis of Alzheimer\u2019s Disease","author":"Morgan","year":"2022","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.nbd.2022.105938_bb0210","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/s41593-018-0154-9","article-title":"A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer\u2019s disease","volume":"21","author":"Mostafavi","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2022.105938_bb0215","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/2051-5960-1-7","article-title":"NG2 cells, a new trail for Alzheimer\u2019s disease mechanisms?","volume":"1","author":"Nielsen","year":"2013","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.nbd.2022.105938_bb0220","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.3233\/JAD-181085","article-title":"A Meta-analysis of Alzheimer\u2019s disease brain transcriptomic data","volume":"68","author":"Patel","year":"2019","journal-title":"J. Alzheimers Dis. JAD"},{"key":"10.1016\/j.nbd.2022.105938_bb0225","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0255-20.2020","article-title":"Donor-specific transcriptomic analysis of Alzheimer\u2019s disease-associated Hypometabolism highlights a unique donor, ribosomal proteins and microglia","volume":"7","author":"Patel","year":"2020","journal-title":"eNeuro"},{"issue":"119","key":"10.1016\/j.nbd.2022.105938_bb0230","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1001\/archopht.119.12.1819","article-title":"The prevalence of glaucoma in a population-based study of Hispanic subjects: Proyecto VER","volume":"1960","author":"Quigley","year":"2001","journal-title":"Arch. Ophthalmol. Chic. Ill"},{"key":"10.1016\/j.nbd.2022.105938_bb0235","doi-asserted-by":"crossref","first-page":"984","DOI":"10.2174\/1567205012666151027124017","article-title":"Differential expression of ribosomal genes in brain and blood of Alzheimer\u2019s disease patients","volume":"12","author":"Rasmussen","year":"2015","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.nbd.2022.105938_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.103929","article-title":"Transcript levels in plasma contribute substantial predictive value as potential Alzheimer\u2019s disease biomarkers in African Americans","volume":"78","author":"Reddy","year":"2022","journal-title":"eBioMedicine"},{"key":"10.1016\/j.nbd.2022.105938_bb0245","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.biopsych.2013.06.003","article-title":"Genetics of Alzheimer\u2019s disease in Caribbean Hispanic and African American populations","volume":"75","author":"Reitz","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2022.105938_bb0250","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"Limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.nbd.2022.105938_bb0255","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","article-title":"edgeR: a Bioconductor package for differential expression analysis of digital gene expression data","volume":"26","author":"Robinson","year":"2010","journal-title":"Bioinforma. Oxf. Engl."},{"key":"10.1016\/j.nbd.2022.105938_bb0260","doi-asserted-by":"crossref","DOI":"10.1002\/ana.26131","article-title":"Polygenic risk score for Alzheimer\u2019s disease in Caribbean Hispanics","author":"Sariya","year":"2021","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2022.105938_bb0265","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1186\/s12864-017-3827-y","article-title":"A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samples","volume":"18","author":"Schuierer","year":"2017","journal-title":"BMC Genomics"},{"key":"10.1016\/j.nbd.2022.105938_bb0270","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s13195-020-00654-x","article-title":"Identification of potential blood biomarkers for early diagnosis of Alzheimer\u2019s disease through RNA sequencing analysis","volume":"12","author":"Shigemizu","year":"2020","journal-title":"Alzheimers Res. Ther."},{"key":"10.1016\/j.nbd.2022.105938_bb0275","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cell.2019.02.048","article-title":"The missing diversity in human genetic studies","volume":"177","author":"Sirugo","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2022.105938_bb0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.107843","article-title":"Alzheimer\u2019s patient microglia exhibit enhanced aging and unique transcriptional activation","volume":"31","author":"Srinivasan","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.nbd.2022.105938_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2020.105129","article-title":"Inclusion of African American\/black adults in a pilot brain proteomics study of Alzheimer\u2019s disease","volume":"146","author":"Stepler","year":"2020","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2022.105938_bb0290","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0021800","article-title":"REVIGO summarizes and visualizes long lists of gene ontology terms","volume":"6","author":"Supek","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2022.105938_bb0295","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/2546261","article-title":"The role of Nephronectin on proliferation and differentiation in human dental pulp stem cells","volume":"2017","author":"Tang","year":"2017","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.nbd.2022.105938_bb0300","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1002\/acn3.223","article-title":"F-box\/LRR-repeat protein 7 is genetically associated with Alzheimer\u2019s disease","volume":"2","author":"Tosto","year":"2015","journal-title":"Ann. Clin. Transl. Neurol."},{"key":"10.1016\/j.nbd.2022.105938_bb0305","doi-asserted-by":"crossref","first-page":"P229","DOI":"10.1016\/j.jalz.2015.07.264","article-title":"O3-05-04: admixture analysis of Alzheimer\u2019s disease in caribbean hispanics","volume":"11","author":"Tosto","year":"2015","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.nbd.2022.105938_bb0310","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.neurobiolaging.2020.05.016","article-title":"Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer\u2019s disease","volume":"94","author":"Vanzulli","year":"2020","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.nbd.2022.105938_bb0315","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/00005072-199501000-00006","article-title":"An improved approach to prepare human brains for research","volume":"54","author":"Vonsattel","year":"1995","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2022.105938_bb0320","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s00401-007-0311-9","article-title":"Twenty-first century brain banking. Processing brains for research: the Columbia University methods","volume":"115","author":"Vonsattel","year":"2008","journal-title":"Acta Neuropathol. (Berl.)"},{"key":"10.1016\/j.nbd.2022.105938_bb0325","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.123431","article-title":"BACE2, a conditional \u03b2-secretase, contributes to Alzheimer\u2019s disease pathogenesis","volume":"4","author":"Wang","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.nbd.2022.105938_bb0330","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.neuron.2020.07.008","article-title":"Missing in action: African ancestry brain research","volume":"107","author":"Weinberger","year":"2020","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2022.105938_bb0335","series-title":"tmod: Feature Set Enrichment Analysis for Metabolomics and Transcriptomics","author":"Weiner","year":"2020"},{"key":"10.1016\/j.nbd.2022.105938_bb0340","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/ana.25543","article-title":"Interleukin 9 alterations linked to alzheimer disease in african americans","volume":"86","author":"Wharton","year":"2019","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2022.105938_bb0345","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/s41588-021-00987-9","article-title":"Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits","volume":"54","author":"Zeng","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.nbd.2022.105938_bb0350","doi-asserted-by":"crossref","first-page":"Article17","DOI":"10.2202\/1544-6115.1128","article-title":"A general framework for weighted gene co-expression network analysis","volume":"4","author":"Zhang","year":"2005","journal-title":"Stat. Appl. Genet. Mol. Biol."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996122003308?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996122003308?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:36:56Z","timestamp":1760852216000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996122003308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":70,"alternative-id":["S0969996122003308"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2022.105938","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.05.28.122234","asserted-by":"object"}]},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2022.105938","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"105938"}}