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Med."},{"key":"10.1016\/j.nbd.2023.106231_bb0375","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/jnr.24155","article-title":"Aquaporins through the brain in health and disease: from water to gas movements","volume":"96","author":"Friscourt","year":"2018","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.nbd.2023.106231_bb0380","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.neuroscience.2012.06.033","article-title":"Delayed increase of astrocytic aquaporin 4 after juvenile traumatic brain injury: possible role in edema resolution?","volume":"222","author":"Fukuda","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.nbd.2023.106231_bb0385","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1038\/jcbfm.2013.118","article-title":"Posttraumatic reduction of edema with aquaporin-4 RNA interference improves acute and chronic functional recovery","volume":"33","author":"Fukuda","year":"2013","journal-title":"J. Cereb. 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Neurol."},{"key":"10.1016\/j.nbd.2023.106231_bb0635","series-title":"Der feinere Bau des Nervensystems im Lichte neuester Forschungen","author":"Lenhoss\u00e9k","year":"1893"},{"key":"10.1016\/j.nbd.2023.106231_bb0640","article-title":"Neurovascular hypoxia after mild traumatic brain injury in juvenile mice correlates with heart\u2013brain dysfunctions in adulthood","volume":"00","author":"Leyba","year":"2023","journal-title":"Acta Physiol."},{"key":"10.1016\/j.nbd.2023.106231_bb0645","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.clineuro.2016.02.032","article-title":"The role of vascular endothelial growth factor and vascular endothelial growth inhibitor in clinical outcome of traumatic brain injury","volume":"144","author":"Li","year":"2016","journal-title":"Clin. Neurol. 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Res."},{"key":"10.1016\/j.nbd.2023.106231_bb0660","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/nature21029","article-title":"Neurotoxic reactive astrocytes are induced by activated microglia","volume":"541","author":"Liddelow","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2023.106231_bb0665","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1590\/S0004-282X2012000300012","article-title":"Aquaporin 9 in rat brain after severe traumatic brain injury","volume":"70","author":"Liu","year":"2012","journal-title":"Arq. Neuropsiquiatr."},{"key":"10.1016\/j.nbd.2023.106231_bb0670","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1007\/s11064-013-1115-z","article-title":"Expression of the NLRP3 inflammasome in cerebral cortex after traumatic brain injury in a rat model","volume":"38","author":"Liu","year":"2013","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.nbd.2023.106231_bb0675","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/sigtrans.2017.23","article-title":"NF-\u03baB signaling in inflammation","volume":"2","author":"Liu","year":"2017","journal-title":"Sig. Transduct. Target. Ther."},{"key":"10.1016\/j.nbd.2023.106231_bb0680","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.3389\/fimmu.2020.01024","article-title":"Interaction of microglia and astrocytes in the neurovascular unit","volume":"11","author":"Liu","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.nbd.2023.106231_bb0685","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s12974-020-01761-0","article-title":"Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injury","volume":"17","author":"Long","year":"2020","journal-title":"J. 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Dis."},{"key":"10.1016\/j.nbd.2023.106231_bb0850","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00401-016-1553-1","article-title":"The role of glial-specific Kir4.1 in normal and pathological states of the CNS","volume":"132","author":"Nwaobi","year":"2016","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2023.106231_bb0855","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s40478-023-01515-y","article-title":"A single mild juvenile TBI in male mice leads to regional brain tissue abnormalities at 12 months of age that correlate with cognitive impairment at the middle age","volume":"11","author":"Obenaus","year":"2023","journal-title":"Acta Neuropathol. 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A."},{"key":"10.1016\/j.nbd.2023.106231_bb0925","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/brain\/aww298","article-title":"Myelin phagocytosis by astrocytes after myelin damage promotes lesion pathology","volume":"140","author":"Ponath","year":"2017","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2023.106231_bb0930","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s12975-011-0126-9","article-title":"A neurovascular perspective for long-term changes after brain trauma","volume":"2","author":"Pop","year":"2011","journal-title":"Transl. Stroke Res."},{"key":"10.1016\/j.nbd.2023.106231_bb0935","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/jcbfm.2012.154","article-title":"Early brain injury alters the blood-brain barrier phenotype in parallel with \u03b2-amyloid and cognitive changes in adulthood","volume":"33","author":"Pop","year":"2013","journal-title":"J. Cereb. 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Res."},{"key":"10.1016\/j.nbd.2023.106231_bb1075","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1089\/neu.2010.1331","article-title":"Vasopressin amplifies the production of proinflammatory mediators in traumatic brain injury","volume":"27","author":"Szmydynger-Chodobska","year":"2010","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.nbd.2023.106231_bb1080","doi-asserted-by":"crossref","first-page":"386","DOI":"10.2183\/pjab.93.024","article-title":"Emerging mechanisms underlying astrogenesis in the developing mammalian brain","volume":"93","author":"Takouda","year":"2017","journal-title":"Proc. Jpn Acad. Ser. B Phys. Biol. Sci."},{"key":"10.1016\/j.nbd.2023.106231_bb1085","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1089\/neu.2012.2488","article-title":"Purinergic 2Y1 receptor stimulation decreases cerebral edema and reactive gliosis in a traumatic brain injury model","volume":"30","author":"Talley Watts","year":"2013","journal-title":"J. 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