{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:24:04Z","timestamp":1792635844908,"version":"4.5.0"},"reference-count":110,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T00:00:00Z","timestamp":1701907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.nbd.2023.106374","type":"journal-article","created":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T21:39:08Z","timestamp":1702417148000},"page":"106374","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Multiple integrated social stress induces depressive-like behavioral and neural adaptations in female C57BL\/6J mice"],"prefix":"10.1016","volume":"190","author":[{"given":"Xiaojing","family":"Zhai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Ai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongyu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengfan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moruo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Xia","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Li","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2023.106374_bb0005","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1503\/jpn.150205","article-title":"Why is depression more prevalent in women?","volume":"40","author":"Albert","year":"2015","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.nbd.2023.106374_bb0010","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1503\/jpn.180026","article-title":"Lifetime major depression and grey-matter volume","volume":"44","author":"Ancelin","year":"2019","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.nbd.2023.106374_bb0015","doi-asserted-by":"crossref","first-page":"7062","DOI":"10.1038\/ncomms8062","article-title":"Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression","volume":"6","author":"Bagot","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2023.106374_bb0020","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.biopsych.2016.06.012","article-title":"Ketamine and imipramine reverse transcriptional signatures of susceptibility and induce resilience-specific gene expression profiles","volume":"81","author":"Bagot","year":"2017","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0025","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1159\/000049028","article-title":"Plasma and cerebrospinal fluid interleukin-6 concentrations in posttraumatic stress disorder","volume":"9","author":"Baker","year":"2001","journal-title":"Neuroimmunomodulation."},{"key":"10.1016\/j.nbd.2023.106374_bb0030","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/npp.2016.169","article-title":"Genetic contributions of inflammation to depression","volume":"42","author":"Barnes","year":"2017","journal-title":"Neuropsychopharmacology."},{"key":"10.1016\/j.nbd.2023.106374_bb0035","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1002\/da.22230","article-title":"Challenging the myth of an \u201cepidemic\u201d of common mental disorders: trends in the global prevalence of anxiety and depression between 1990 and 2010","volume":"31","author":"Baxter","year":"2014","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.nbd.2023.106374_bb0040","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s13293-016-0087-5","article-title":"Female rats are not more variable than male rats: a meta-analysis of neuroscience studies","volume":"7","author":"Becker","year":"2016","journal-title":"Biol. Sex Differ."},{"key":"10.1016\/j.nbd.2023.106374_bb0045","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.neubiorev.2010.07.002","article-title":"Sex bias in neuroscience and biomedical research","volume":"35","author":"Beery","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.nbd.2023.106374_bb0050","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1126\/science.1120972","article-title":"Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress","volume":"311","author":"Berton","year":"2006","journal-title":"Science."},{"key":"10.1016\/j.nbd.2023.106374_bb0055","doi-asserted-by":"crossref","first-page":"158","DOI":"10.21315\/mjms2021.28.3.16","article-title":"Exposure to domestic violence during the COVID-19 pandemic: a potent threat to the mental well-being of children","volume":"28","author":"Boo","year":"2021","journal-title":"Malays. J. Med. Sci."},{"key":"10.1016\/j.nbd.2023.106374_bb0060","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/209223a0","article-title":"Behavioural correlates of the oestrous cycle in the rat","volume":"209","author":"Burke","year":"1966","journal-title":"Nature."},{"key":"10.1016\/j.nbd.2023.106374_bb0065","doi-asserted-by":"crossref","DOI":"10.3791\/58184","article-title":"The unpredictable chronic mild stress protocol for inducing anhedonia in mice","author":"Burstein","year":"2018","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.nbd.2023.106374_bb0070","doi-asserted-by":"crossref","first-page":"13877","DOI":"10.1038\/ncomms13877","article-title":"Dopaminergic dynamics underlying sex-specific cocaine reward","volume":"8","author":"Calipari","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2023.106374_bb0075","article-title":"The mouse forced swim test","volume":"e3638","author":"Can","year":"2012","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.nbd.2023.106374_bb0080","doi-asserted-by":"crossref","first-page":"16453","DOI":"10.1523\/JNEUROSCI.3177-10.2010","article-title":"Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action","volume":"30","author":"Cao","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2023.106374_bb0085","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","article-title":"Quantitative assessment of tactile allodynia in the rat paw","volume":"53","author":"Chaplan","year":"1994","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.nbd.2023.106374_bb0090","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/nature11713","article-title":"Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons","volume":"493","author":"Chaudhury","year":"2013","journal-title":"Nature."},{"key":"10.1016\/j.nbd.2023.106374_bb0095","first-page":"651","article-title":"Current understanding of the neurobiology of major depressive disorder","volume":"56","author":"Chirita","year":"2015","journal-title":"Romanian J. Morphol. Embryol."},{"key":"10.1016\/j.nbd.2023.106374_bb0100","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.neuron.2017.05.020","article-title":"Dorsal raphe dopamine neurons modulate arousal and promote wakefulness by salient stimuli","volume":"94","author":"Cho","year":"2017","journal-title":"Neuron."},{"key":"10.1016\/j.nbd.2023.106374_bb0105","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/509282a","article-title":"Policy: NIH to balance sex in cell and animal studies","volume":"509","author":"Clayton","year":"2014","journal-title":"Nature."},{"key":"10.1016\/j.nbd.2023.106374_bb0110","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1001\/archpsyc.57.1.21","article-title":"Adolescent onset of the gender difference in lifetime rates of major depression: a theoretical model","volume":"57","author":"Cyranowski","year":"2000","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0115","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.biopsych.2013.12.014","article-title":"Effects of striatal DeltaFosB overexpression and ketamine on social defeat stress-induced anhedonia in mice","volume":"76","author":"Donahue","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2023.09.004","article-title":"Stress relief as a natural resilience mechanism against depression-like behaviors","author":"Dong","year":"2023","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2023.106374_bb0125","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.biopsych.2006.02.013","article-title":"A neurotrophic model for stress-related mood disorders","volume":"59","author":"Duman","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0130","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s13031-021-00377-2","article-title":"Conflict-related violence and mental health among self-settled Democratic Republic of Congo female refugees in Kampala, Uganda - a respondent driven sampling survey","volume":"15","author":"Familiar","year":"2021","journal-title":"Confl. Heal."},{"key":"10.1016\/j.nbd.2023.106374_bb0135","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/s41596-018-0116-4","article-title":"Using the tube test to measure social hierarchy in mice","volume":"14","author":"Fan","year":"2019","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.nbd.2023.106374_bb0140","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.cell.2022.12.033","article-title":"Neural mechanism underlying depressive-like state associated with social status loss","volume":"186","author":"Fan","year":"2023","journal-title":"Cell."},{"key":"10.1016\/j.nbd.2023.106374_bb0145","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1126\/science.abi7270","article-title":"Neurobiology of novelty seeking","volume":"372","author":"Farahbakhsh","year":"2021","journal-title":"Science."},{"key":"10.1016\/j.nbd.2023.106374_bb0150","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1001\/archinte.164.9.1010","article-title":"Depression and C-reactive protein in US adults: data from the third national health and nutrition examination survey","volume":"164","author":"Ford","year":"2004","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.nbd.2023.106374_bb0155","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1126\/science.1249240","article-title":"Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience","volume":"344","author":"Friedman","year":"2014","journal-title":"Science."},{"key":"10.1016\/j.nbd.2023.106374_bb0160","doi-asserted-by":"crossref","first-page":"11671","DOI":"10.1038\/ncomms11671","article-title":"KCNQ channel openers reverse depressive symptoms via an active resilience mechanism","volume":"7","author":"Friedman","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2023.106374_bb0165","series-title":"Comparative Psychology Monographs","first-page":"1","article-title":"Relation between spontaneous activity and estrous cycle in the white rat","author":"GH","year":"1923"},{"key":"10.1016\/j.nbd.2023.106374_bb0170","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1348\/147608308X379806","article-title":"The dark side of competition: how competitive behaviour and striving to avoid inferiority are linked to depression, anxiety, stress and self-harm","volume":"82","author":"Gilbert","year":"2009","journal-title":"Psychol. Psychother."},{"key":"10.1016\/j.nbd.2023.106374_bb0175","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1038\/nprot.2011.361","article-title":"A standardized protocol for repeated social defeat stress in mice","volume":"6","author":"Golden","year":"2011","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.nbd.2023.106374_bb0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0224499","article-title":"Indirect violence exposure and mental health symptoms among an urban public-school population: prevalence and correlates","volume":"14","author":"Gollub","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2023.106374_bb0185","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.physbeh.2018.09.001","article-title":"Social instability in female rodents as a model of stress related disorders: a systematic review","volume":"196","author":"Goni-Balentziaga","year":"2018","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.nbd.2023.106374_bb0190","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.copsyc.2021.06.015","article-title":"Emotionally focused therapy: attachment, connection, and health","volume":"43","author":"Greenman","year":"2021","journal-title":"Curr. Opin. Psychol."},{"key":"10.1016\/j.nbd.2023.106374_bb0195","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0361-9230(99)00087-8","article-title":"Defeat is a major stressor in males while social instability is stressful mainly in females: towards the development of a social stress model in female rats","volume":"50","author":"Haller","year":"1999","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.nbd.2023.106374_bb0200","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1038\/npp.2017.259","article-title":"A novel method for chronic social defeat stress in female mice","volume":"43","author":"Harris","year":"2018","journal-title":"Neuropsychopharmacology."},{"key":"10.1016\/j.nbd.2023.106374_bb0205","article-title":"Does the type of exposure to workplace violence matter to nurses\u2019 mental health?","volume":"9","author":"Havaei","year":"2021","journal-title":"Healthcare (Basel)"},{"key":"10.1016\/j.nbd.2023.106374_bb0210","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.neuroscience.2009.01.059","article-title":"Chronic social instability stress in female rats: a potential animal model for female depression","volume":"159","author":"Herzog","year":"2009","journal-title":"Neuroscience."},{"key":"10.1016\/j.nbd.2023.106374_bb0215","doi-asserted-by":"crossref","first-page":"16136","DOI":"10.1073\/pnas.1415191111","article-title":"Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress","volume":"111","author":"Hodes","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2023.106374_bb0220","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.biopsych.2017.07.014","article-title":"Vicarious social defeat stress induces depression-related outcomes in female mice","volume":"83","author":"Iniguez","year":"2018","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0225","series-title":"Veteran and Military Mental Health Issues","author":"Inoue","year":"2021"},{"key":"10.1016\/j.nbd.2023.106374_bb0230","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/01.jcp.0000168879.03169.ce","article-title":"Sex differences in antidepressant response in recent antidepressant clinical trials","volume":"25","author":"Khan","year":"2005","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/j.nbd.2023.106374_bb0235","doi-asserted-by":"crossref","first-page":"652","DOI":"10.30773\/pi.2021.0067","article-title":"Social isolation, loneliness and their relationships with mental health status in South Korea","volume":"18","author":"Kim","year":"2021","journal-title":"Psychiatry Investig."},{"key":"10.1016\/j.nbd.2023.106374_bb0240","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/978-1-4939-8994-2_4","article-title":"The elevated plus maze test for measuring anxiety-like behavior in rodents","volume":"1916","author":"Kraeuter","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.nbd.2023.106374_bb0245","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.cell.2007.09.018","article-title":"Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions","volume":"131","author":"Krishnan","year":"2007","journal-title":"Cell."},{"key":"10.1016\/j.nbd.2023.106374_bb0250","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1192\/bjpo.bp.115.001362","article-title":"Testing the social competition hypothesis of depression using a simple economic game","volume":"2","author":"Kupferberg","year":"2016","journal-title":"BJPsych Open"},{"key":"10.1016\/j.nbd.2023.106374_bb0255","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/mp.2017.76","article-title":"Gene deficiency and pharmacological inhibition of caspase-1 confers resilience to chronic social defeat stress via regulating the stability of surface AMPARs","volume":"23","author":"Li","year":"2018","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0260","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.neuroimage.2015.06.012","article-title":"Hippocampal volume and functional connectivity changes during the female menstrual cycle","volume":"118","author":"Lisofsky","year":"2015","journal-title":"Neuroimage."},{"key":"10.1016\/j.nbd.2023.106374_bb0265","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0029395","article-title":"Acid solution is a suitable medium for introducing QX-314 into nociceptors through TRPV1 channels to produce sensory-specific analgesic effects","volume":"6","author":"Liu","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2023.106374_bb0270","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1177\/1535370213477985","article-title":"Protective effects of luteolin on cognitive impairments induced by psychological stress in mice","volume":"238","author":"Liu","year":"2013","journal-title":"Exp. Biol. Med. (Maywood)"},{"key":"10.1016\/j.nbd.2023.106374_bb0275","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/j.pain.0000000000001083","article-title":"Brain-derived neurotrophic factor-mediated projection-specific regulation of depressive-like and nociceptive behaviors in the mesolimbic reward circuitry","volume":"159","author":"Liu","year":"2018","journal-title":"Pain."},{"key":"10.1016\/j.nbd.2023.106374_bb0280","doi-asserted-by":"crossref","first-page":"7646","DOI":"10.12659\/MSM.908422","article-title":"Anti-depressant-like effect of sinomenine on chronic unpredictable mild stress-induced depression in a mouse model","volume":"24","author":"Liu","year":"2018","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.nbd.2023.106374_bb0285","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1038\/s41386-020-0713-0","article-title":"Mesocortical BDNF signaling mediates antidepressive-like effects of lithium","volume":"45","author":"Liu","year":"2020","journal-title":"Neuropsychopharmacology."},{"key":"10.1016\/j.nbd.2023.106374_bb0290","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.1016\/j.biopsych.2019.08.007","article-title":"Adapting social defeat stress for female mice using species-typical interfemale aggression","volume":"86","author":"Logan","year":"2019","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0295","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.biopsych.2021.03.010","article-title":"Defining valid chronic stress models for depression with female rodents","volume":"90","author":"Lopez","year":"2021","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0300","doi-asserted-by":"crossref","first-page":"3573267","DOI":"10.1155\/2020\/3573267","article-title":"A game theory-based model for predicting depression due to frustration in competitive environments","volume":"2020","author":"Loula","year":"2020","journal-title":"Comput. Math. Methods Med."},{"key":"10.1016\/j.nbd.2023.106374_bb0305","doi-asserted-by":"crossref","first-page":"4525","DOI":"10.1523\/JNEUROSCI.2298-22.2023","article-title":"Disinhibition of mesolimbic dopamine circuit by the lateral hypothalamus regulates pain sensation","volume":"43","author":"Ma","year":"2023","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2023.106374_bb0310","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1006\/cyto.1997.0238","article-title":"Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression","volume":"9","author":"Maes","year":"1997","journal-title":"Cytokine."},{"key":"10.1016\/j.nbd.2023.106374_bb0315","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1016\/S0140-6736(18)31948-2","article-title":"Depression","volume":"392","author":"Malhi","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2023.106374_bb0320","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.comppsych.2007.06.012","article-title":"Sex differences in depression symptoms in treatment-seeking adults: confirmatory analyses from the sequenced treatment alternatives to relieve depression study","volume":"49","author":"Marcus","year":"2008","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0325","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0006-8993(99)01439-0","article-title":"Estrous cycle modulation of extracellular serotonin in mediobasal hypothalamus: role of the serotonin transporter and terminal autoreceptors","volume":"831","author":"Maswood","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2023.106374_bb0330","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.2044-8260.2011.02010.x","article-title":"An exploration of competitiveness and caring in relation to psychopathology","volume":"51","author":"McEwan","year":"2012","journal-title":"Br. J. Clin. Psychol."},{"key":"10.1016\/j.nbd.2023.106374_bb0335","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1038\/s41593-017-0010-3","article-title":"Social stress induces neurovascular pathology promoting depression","volume":"20","author":"Menard","year":"2017","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2023.106374_bb0340","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1096\/fj.201600781r","article-title":"Considering sex as a biological variable in preclinical research","volume":"31","author":"Miller","year":"2017","journal-title":"FASEB J."},{"key":"10.1016\/j.nbd.2023.106374_bb0345","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1016\/j.jpsychires.2013.08.020","article-title":"Interleukin-1beta is associated with depressive episode in major depression but not in bipolar disorder","volume":"47","author":"Mota","year":"2013","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.nbd.2023.106374_bb0350","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1016\/j.lfs.2012.09.023","article-title":"Effects of fluoxetine, tianeptine and olanzapine on unpredictable chronic mild stress-induced depression-like behavior in mice","volume":"91","author":"Mutlu","year":"2012","journal-title":"Life Sci."},{"key":"10.1016\/j.nbd.2023.106374_bb0355","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.psychres.2010.07.042","article-title":"Co-occurring mental and substance abuse disorders: a review on the potential predictors and clinical outcomes","volume":"186","author":"Najt","year":"2011","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.nbd.2023.106374_bb0360","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.biopsych.2019.06.030","article-title":"Multidimensional predictors of susceptibility and resilience to social defeat stress","volume":"86","author":"Nasca","year":"2019","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0365","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.biopsych.2019.05.005","article-title":"Fighting females: neural and behavioral consequences of social defeat stress in female mice","volume":"86","author":"Newman","year":"2019","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0370","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.biopsycho.2014.03.009","article-title":"Interleukin-6 and soluble interleukin-6 receptor levels in posttraumatic stress disorder: associations with lifetime diagnostic status and psychological context","volume":"99","author":"Newton","year":"2014","journal-title":"Biol. Psychol."},{"key":"10.1016\/j.nbd.2023.106374_bb0375","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.biopsych.2018.09.030","article-title":"Interleukin-6 induced by social stress promotes a unique transcriptional signature in the monocytes that facilitate anxiety","volume":"85","author":"Niraula","year":"2019","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0380","first-page":"65","article-title":"Models of depression: unpredictable chronic mild stress in mice","author":"Nollet","year":"2013","journal-title":"Curr. Protoc. Pharmacol."},{"key":"10.1016\/j.nbd.2023.106374_bb0385","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1034\/j.1600-0447.2001.00162.x","article-title":"Raised levels of plasma interleukin-1beta in major and postviral depression","volume":"103","author":"Owen","year":"2001","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.nbd.2023.106374_bb0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2021.05.002","article-title":"The resilient phenotype induced by prophylactic ketamine exposure during adolescence is mediated by the ventral tegmental area-nucleus accumbens pathway","author":"Parise","year":"2021","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0395","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1080\/10253890.2019.1673360","article-title":"Interleukin-1alpha in the ventral hippocampus increases stress vulnerability and inflammation-related processes","volume":"23","author":"Pearson-Leary","year":"2020","journal-title":"Stress."},{"key":"10.1016\/j.nbd.2023.106374_bb0400","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jad.2021.04.066","article-title":"Association between household overcrowding and depressive mood among Chinese residents","volume":"290","author":"Pengcheng","year":"2021","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.nbd.2023.106374_bb0405","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.psyneuen.2014.05.005","article-title":"Alterations in dopamine system function across the estrous cycle of the MAM rodent model of schizophrenia","volume":"47","author":"Perez","year":"2014","journal-title":"Psychoneuroendocrinology."},{"key":"10.1016\/j.nbd.2023.106374_bb0410","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1001\/archgenpsychiatry.2009.58","article-title":"A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men","volume":"66","author":"Perry","year":"2009","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0415","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neubiorev.2014.01.001","article-title":"Female mice liberated for inclusion in neuroscience and biomedical research","volume":"40","author":"Prendergast","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.nbd.2023.106374_bb0420","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.psyneuen.2017.01.014","article-title":"Estradiol is a critical regulator of food-reward behavior","volume":"78","author":"Richard","year":"2017","journal-title":"Psychoneuroendocrinology."},{"key":"10.1016\/j.nbd.2023.106374_bb0425","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.1896","article-title":"What it takes to be at the top: the interrelationship between chronic social stress and social dominance","volume":"10","author":"\u0160abanovi\u0107","year":"2020","journal-title":"Brain Behav."},{"key":"10.1016\/j.nbd.2023.106374_bb0430","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpsychores.2019.109814","article-title":"Identifying subgroups of refugees from Syria resettled in Sweden based on multiple trauma exposures: a latent class analysis of trauma history and mental health outcomes","volume":"125","author":"Sengoelge","year":"2019","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.nbd.2023.106374_bb0435","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.18726","article-title":"Sexually dimorphic neuronal responses to social isolation","volume":"5","author":"Senst","year":"2016","journal-title":"Elife."},{"key":"10.1016\/j.nbd.2023.106374_bb0440","first-page":"334","article-title":"Genetics factors in major depression disease","volume":"9","author":"Shadrina","year":"2018","journal-title":"Front. Psychol."},{"key":"10.1016\/j.nbd.2023.106374_bb0445","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.amepre.2019.03.018","article-title":"Housing disadvantage and poor mental health: a systematic review","volume":"57","author":"Singh","year":"2019","journal-title":"Am. J. Prev. Med."},{"key":"10.1016\/j.nbd.2023.106374_bb0450","doi-asserted-by":"crossref","first-page":"12838","DOI":"10.1038\/s41598-017-12811-8","article-title":"Establishment of a repeated social defeat stress model in female mice","volume":"7","author":"Takahashi","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2023.106374_bb0455","article-title":"Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder","author":"Tan","year":"2018","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0460","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017405","article-title":"Sex differences in social interaction behavior following social defeat stress in the monogamous California mouse (Peromyscus californicus)","volume":"6","author":"Trainor","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2023.106374_bb0465","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1080\/10253890.2020.1864319","article-title":"Chronic social defeat stress in female mice leads to sex-specific behavioral and neuroendocrine effects","volume":"24","author":"van Doeselaar","year":"2021","journal-title":"Stress."},{"key":"10.1016\/j.nbd.2023.106374_bb0470","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1017\/S0033291717003178","article-title":"Sex similarities and differences in risk factors for recurrence of major depression","volume":"48","author":"van Loo","year":"2018","journal-title":"Psychol. Med."},{"key":"10.1016\/j.nbd.2023.106374_bb0475","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/nn.2551","article-title":"DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses","volume":"13","author":"Vialou","year":"2010","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2023.106374_bb0480","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/nn.3591","article-title":"Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway","volume":"17","author":"Walsh","year":"2014","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2023.106374_bb0485","doi-asserted-by":"crossref","first-page":"2802","DOI":"10.12998\/wjcc.v8.i13.2802","article-title":"Correlation between crowdedness in emergency departments and anxiety in Chinese patients","volume":"8","author":"Wang","year":"2020","journal-title":"World J. Clin. Cases"},{"key":"10.1016\/j.nbd.2023.106374_bb0490","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1016\/S0140-6736(13)61611-6","article-title":"Global burden of disease attributable to mental and substance use disorders: findings from the global burden of disease study 2010","volume":"382","author":"Whiteford","year":"2013","journal-title":"Lancet."},{"key":"10.1016\/j.nbd.2023.106374_bb0495","series-title":"Depressive Disorder (Depression)","author":"WHO","year":"2023"},{"key":"10.1016\/j.nbd.2023.106374_bb0500","doi-asserted-by":"crossref","first-page":"8876230","DOI":"10.1155\/2020\/8876230","article-title":"Predisposition of neonatal maternal separation to visceral hypersensitivity via downregulation of small-conductance calcium-activated potassium channel subtype 2 (SK2) in mice","volume":"2020","author":"Wu","year":"2020","journal-title":"Neural Plast."},{"key":"10.1016\/j.nbd.2023.106374_bb0505","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/jnc.14641","article-title":"Validation of the targeted metabolomic pathway in the hippocampus and comparative analysis with the prefrontal cortex of social defeat model mice","volume":"149","author":"Xu","year":"2019","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2023.106374_bb0510","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.2147\/NDT.S247497","article-title":"The long-term effects of adolescent social defeat stress on oligodendrocyte lineage cells and neuroinflammatory mediators in mice","volume":"16","author":"Xu","year":"2020","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"10.1016\/j.nbd.2023.106374_bb0515","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1002\/ptr.3456","article-title":"Antidepressant-like effects of L-theanine in the forced swim and tail suspension tests in mice","volume":"25","author":"Yin","year":"2011","journal-title":"Phytother. Res."},{"key":"10.1016\/j.nbd.2023.106374_bb0520","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2019.107780","article-title":"Social instability is an effective chronic stress paradigm for both male and female mice","volume":"160","author":"Yohn","year":"2019","journal-title":"Neuropharmacology."},{"key":"10.1016\/j.nbd.2023.106374_bb0525","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.biopsych.2017.02.1180","article-title":"Brain-derived neurotrophic factor in the mesolimbic reward circuitry mediates nociception in chronic neuropathic pain","volume":"82","author":"Zhang","year":"2017","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0530","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1097\/ALN.0000000000001720","article-title":"Astroglial MicroRNA-219-5p in the ventral tegmental area regulates nociception in rats","volume":"127","author":"Zhang","year":"2017","journal-title":"Anesthesiology."},{"key":"10.1016\/j.nbd.2023.106374_bb0535","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.biopsych.2018.08.020","article-title":"alpha1- and beta3-adrenergic receptor-mediated mesolimbic homeostatic plasticity confers resilience to social stress in susceptible mice","volume":"85","author":"Zhang","year":"2019","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2023.106374_bb0540","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2023.106776","article-title":"Neural and molecular investigation into the paraventricular thalamic-nucleus accumbens circuit for pain sensation and non-opioid analgesia","volume":"191","author":"Zhang","year":"2023","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.nbd.2023.106374_bb0545","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.650793","article-title":"Behaviors related to psychiatric disorders and pain perception in C57BL\/6J mice during different phases of estrous cycle","volume":"15","author":"Zhao","year":"2021","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.nbd.2023.106374_bb0550","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1126\/science.aak9726","article-title":"History of winning remodels thalamo-PFC circuit to reinforce social dominance","volume":"357","author":"Zhou","year":"2017","journal-title":"Science."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096999612300390X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096999612300390X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:40:35Z","timestamp":1760852435000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S096999612300390X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":110,"alternative-id":["S096999612300390X"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2023.106374","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiple integrated social stress induces depressive-like behavioral and neural adaptations in female C57BL\/6J mice","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2023.106374","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106374"}}