{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:26:24Z","timestamp":1792106784934,"version":"4.4.0"},"reference-count":118,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.nbd.2024.106436","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T17:40:03Z","timestamp":1707414003000},"page":"106436","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Navigating the future of retinitis pigmentosa treatments: A comprehensive analysis of therapeutic approaches in rd10 mice"],"prefix":"10.1016","volume":"193","author":[{"given":"Hongli","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaorong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2024.106436_bb0005","doi-asserted-by":"crossref","first-page":"5713","DOI":"10.1167\/iovs.10-6269","article-title":"AAV-mediated gene replacement, either alone or in combination with physical and pharmacological agents, results in partial and transient protection from photoreceptor degeneration associated with betaPDE deficiency","volume":"52","author":"Allocca","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0010","doi-asserted-by":"crossref","first-page":"913","DOI":"10.3390\/pharmaceutics12100913","article-title":"Inhibition of MicroRNA 6937 delays photoreceptor and vision loss in a mouse model of retinitis Pigmentosa","volume":"12","author":"Anasagasti","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.nbd.2024.106436_bb0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0112142","article-title":"Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration","volume":"9","author":"Arango-Gonzalez","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2024.106436_bb0020","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jsbmb.2019.01.007","article-title":"Progesterone anti-inflammatory properties in hereditary retinal degeneration","volume":"189","author":"Benlloch-Navarro","year":"2019","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.nbd.2024.106436_bb0025","series-title":"Overview of Retinal Gene Therapy: Current Status and Future Challenges","first-page":"a041278","author":"Bennett","year":"2022"},{"key":"10.1016\/j.nbd.2024.106436_bb0030","doi-asserted-by":"crossref","first-page":"2955","DOI":"10.1073\/pnas.90.7.2955","article-title":"Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase","volume":"90","author":"Bowes","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2024.106436_bb0035","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.ophtha.2003.05.010","article-title":"Prevalence and causes of visual impairment and blindness among 9980 Scandinavian adults: the Copenhagen City eye study","volume":"111","author":"Buch","year":"2004","journal-title":"Ophthalmology"},{"key":"10.1016\/j.nbd.2024.106436_bb0040","first-page":"264","article-title":"The synthetic progestin norgestrel acts to increase LIF levels in the rd10 mouse model of retinitis pigmentosa","volume":"22","author":"Byrne","year":"2016","journal-title":"Mol. Vis."},{"key":"10.1016\/j.nbd.2024.106436_bb0045","doi-asserted-by":"crossref","first-page":"5176","DOI":"10.1111\/jcmm.14391","article-title":"The urokinase-type plasminogen activator system as drug target in retinitis pigmentosa: new pre-clinical evidence in the rd10 mouse model","volume":"23","author":"Cammalleri","year":"2019","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.nbd.2024.106436_bb0050","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.811257","article-title":"Sulforaphane modulates the inflammation and delays neurodegeneration on a retinitis pigmentosa mice model","volume":"13","author":"Canto","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.nbd.2024.106436_bb0055","doi-asserted-by":"crossref","first-page":"1040090","DOI":"10.3389\/fncel.2022.1040090","article-title":"Differences in the spatial fidelity of evoked and spontaneous signals in the degenerating retina","volume":"16","author":"Carleton","year":"2022","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0060","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.202215941","article-title":"miR-181a\/b downregulation: a mutation-independent therapeutic approach for inherited retinal diseases","volume":"14","author":"Carrella","year":"2022","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.nbd.2024.106436_bb0065","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0042-6989(01)00146-8","article-title":"Retinal degeneration mutants in the mouse","volume":"42","author":"Chang","year":"2002","journal-title":"Vis. Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0070","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.visres.2006.11.020","article-title":"Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene","volume":"47","author":"Chang","year":"2007","journal-title":"Vis. Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0075","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1172\/JCI125898","article-title":"Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration","volume":"130","author":"Charish","year":"2020","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2024.106436_bb0080","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1080\/15569527.2019.1685535","article-title":"(Z)-7,4\u2019-Dimethoxy-6-hydroxy-aurone-4-O-\u03b2-glucopyranoside mitigates retinal degeneration in Rd10 mouse model through inhibiting oxidative stress and inflammatory responses","volume":"39","author":"Chen","year":"2020","journal-title":"Cutan. Ocul. Toxicol."},{"key":"10.1016\/j.nbd.2024.106436_bb0085","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1080\/14712598.2020.1740676","article-title":"Voretigene neparvovec-rzyl for treatment of RPE65-mediated inherited retinal diseases: a model for ocular gene therapy development","volume":"20","author":"Ciulla","year":"2020","journal-title":"Expert. Opin. Biol. Ther."},{"key":"10.1016\/j.nbd.2024.106436_bb0090","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.822359","article-title":"Intravitreal administration of rhNGF enhances regenerative processes in a zebrafish model of retinal degeneration","volume":"13","author":"Cocchiaro","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.nbd.2024.106436_bb0095","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nm.3793","article-title":"Therapeutic genome editing: prospects and challenges","volume":"21","author":"Cox","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.nbd.2024.106436_bb0100","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1038\/s41418-020-00636-4","article-title":"Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration","volume":"28","author":"Deng","year":"2021","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.nbd.2024.106436_bb0105","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1111\/j.1471-4159.2011.07354.x","article-title":"Enhancing survival of photoreceptor cells in vivo using the synthetic progestin Norgestrel","volume":"118","author":"Doonan","year":"2011","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2024.106436_bb0110","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/1350-9462(94)90004-3","article-title":"The rd mouse story: seventy years of research on an animal model of inherited retinal degeneration","volume":"12","author":"Farber","year":"1994","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0115","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0282174","article-title":"Rhodopsin-positive cell production by intravitreal injection of small molecule compounds in mouse models of retinal degeneration","volume":"18","author":"Fujii","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2024.106436_bb0120","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1007\/s12031-020-01503-0","article-title":"Increased neuroprotective microglia and photoreceptor survival in the retina from a peptide inhibitor of myeloid differentiation factor 88 (MyD88)","volume":"70","author":"Garces","year":"2020","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0125","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1111\/cns.12805","article-title":"Rasagiline delays retinal degeneration in a mouse model of retinitis pigmentosa via modulation of Bax\/Bcl-2 expression","volume":"24","author":"Garcia-Delgado","year":"2018","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.nbd.2024.106436_bb0130","doi-asserted-by":"crossref","first-page":"10177","DOI":"10.1096\/fj.201900414R","article-title":"Rescuing cones and daylight vision in retinitis pigmentosa mice","volume":"33","author":"Guadagni","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.nbd.2024.106436_bb0135","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.exer.2012.08.013","article-title":"Knockout of ccr2 alleviates photoreceptor cell death in a model of retinitis pigmentosa","volume":"104","author":"Guo","year":"2012","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0140","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/aac811","article-title":"Feasibility study for a glutamate driven subretinal prosthesis: local subretinal application of glutamate on blind retina evoke network-mediated responses in different types of ganglion cells","volume":"15","author":"Haq","year":"2018","journal-title":"J. Neural Eng."},{"key":"10.1016\/j.nbd.2024.106436_bb0145","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1016\/S0140-6736(06)69740-7","article-title":"Retinitis pigmentosa","volume":"368","author":"Hartong","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.nbd.2024.106436_bb0150","article-title":"Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma","volume":"4","author":"Hasegawa","year":"2018","journal-title":"Heliyon"},{"key":"10.1016\/j.nbd.2024.106436_bb0155","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.exer.2019.04.008","article-title":"PEDF peptides promote photoreceptor survival in rd10 retina models","volume":"184","author":"Hern\u00e1ndez-Pinto","year":"2019","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0160","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/15569527.2018.1441863","article-title":"(3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one ameliorates retinal degeneration in Pde6brd10mice","volume":"37","author":"Hu","year":"2018","journal-title":"Cutan. Ocul. Toxicol."},{"key":"10.1016\/j.nbd.2024.106436_bb0165","doi-asserted-by":"crossref","first-page":"6196","DOI":"10.1167\/iovs.15-16795","article-title":"Erp29 attenuates cigarette smoke extract-induced endoplasmic reticulum stress and mitigates tight junction damage in retinal pigment epithelial cells","volume":"56","author":"Huang","year":"2015","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0170","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.tins.2012.03.007","article-title":"p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity","volume":"35","author":"Ib\u00e1\u00f1ez","year":"2012","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0175","doi-asserted-by":"crossref","first-page":"5970","DOI":"10.1038\/srep05970","article-title":"Novel VCP modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa","volume":"4","author":"Ikeda","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2024.106436_bb0180","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.stemcr.2018.01.032","article-title":"Establishment of Immunodeficient retinal degeneration model mice and functional maturation of human ESC-derived retinal sheets after transplantation","volume":"10","author":"Iraha","year":"2018","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.nbd.2024.106436_bb0185","doi-asserted-by":"crossref","first-page":"3610","DOI":"10.1167\/iovs.16-19300","article-title":"Intravitreal injection of proinsulin-loaded microspheres delays photoreceptor cell death and vision loss in the rd10 mouse model of retinitis pigmentosa","volume":"57","author":"Isiegas","year":"2016","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0190","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/jnc.13388","article-title":"Progesterone receptor signalling in retinal photoreceptor neuroprotection","volume":"136","author":"Jackson","year":"2016","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2024.106436_bb0195","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1038\/s41587-021-00943-2","article-title":"Adenine base editor engineering reduces editing of bystander cytosines","volume":"39","author":"Jeong","year":"2021","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.nbd.2024.106436_bb0200","doi-asserted-by":"crossref","first-page":"16016","DOI":"10.1523\/JNEUROSCI.2203-13.2013","article-title":"Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia","volume":"33","author":"Johansson","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0205","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.5966\/sctm.2013-0013","article-title":"Genetically modified neural stem cells for a local and sustained delivery of neuroprotective factors to the dystrophic mouse retina","volume":"2","author":"Jung","year":"2013","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.nbd.2024.106436_bb0210","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1177\/112067210401400405","article-title":"Progesterone administration fails to protect albino male rats against photostress-induced retinal degeneration","volume":"14","author":"K\u00e1ldi","year":"2004","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.nbd.2024.106436_bb0215","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.exer.2015.10.019","article-title":"Using the rd1 mouse to understand functional and anatomical retinal remodelling and treatment implications in retinitis pigmentosa: a review","volume":"150","author":"Kalloniatis","year":"2016","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0220","doi-asserted-by":"crossref","first-page":"eaau6977","DOI":"10.1126\/science.aau6977","article-title":"The biology, function,and biomedical applications of exosomes","volume":"367","author":"Kalluri","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.nbd.2024.106436_bb0225","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1080\/02713683.2017.1358371","article-title":"Protective effect of sulforaphane against retinal degeneration in the Pde6rd10 mouse model of retinitis pigmentosa","volume":"42","author":"Kang","year":"2017","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0230","doi-asserted-by":"crossref","first-page":"22632","DOI":"10.1038\/srep22632","article-title":"Carnosic acid slows photoreceptor degeneration in the Pde6brd10 mouse model of retinitis pigmentosa","volume":"6","author":"Kang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2024.106436_bb0235","doi-asserted-by":"crossref","first-page":"3816","DOI":"10.4049\/jimmunol.1301738","article-title":"CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration","volume":"192","author":"Kohno","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.nbd.2024.106436_bb0240","doi-asserted-by":"crossref","first-page":"11515","DOI":"10.3390\/ijms222111515","article-title":"Functional availability of ON-bipolar cells in the degenerated retina: timing and longevity of an Optogenetic gene therapy","volume":"22","author":"Kralik","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0245","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1159\/000526317","article-title":"Gene therapy for inherited retinal disease: long-term durability of effect","volume":"66","author":"Leroy","year":"2022","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0250","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1080\/15569527.2016.1265551","article-title":"2R,3S2R,3S-Pinobanksin-3-cinnamate ameliorates photoreceptor degeneration in Pde6rd10 mice","volume":"36","author":"Li","year":"2017","journal-title":"Cutan. Ocul. Toxicol."},{"key":"10.1016\/j.nbd.2024.106436_bb0255","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1111\/jnc.15472","article-title":"Wolfberry-derived zeaxanthin dipalmitate delays retinal degeneration in a mouse model of retinitis pigmentosa through modulating STAT3, CCL2 and MAPK pathways","volume":"158","author":"Liu","year":"2021","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2024.106436_bb0260","doi-asserted-by":"crossref","first-page":"4883","DOI":"10.3390\/ijms23094883","article-title":"Retinitis pigmentosa: progress in molecular pathology and Biotherapeutical strategies","volume":"23","author":"Liu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0265","first-page":"5","article-title":"Photoreceptor protection by mesencephalic astrocyte-derived neurotrophic factor (MANF)","author":"Lu","year":"2018","journal-title":"eNeuro"},{"key":"10.1016\/j.nbd.2024.106436_bb0270","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/S1350-9462(03)00039-9","article-title":"Neural remodeling in retinal degeneration","volume":"22","author":"Marc","year":"2003","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0275","doi-asserted-by":"crossref","first-page":"11764","DOI":"10.1038\/srep11764","article-title":"Adalimumab reduces photoreceptor cell death in a mouse model of retinal degeneration","volume":"5","author":"Mart\u00ednez-Fern\u00e1ndez de la C\u00e1mara","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2024.106436_bb0280","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1089\/ars.2015.6509","article-title":"The Thioredoxin encoded by the rod-derived cone viability factor gene protects cone photoreceptors against oxidative stress","volume":"24","author":"Mei","year":"2016","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.nbd.2024.106436_bb0285","doi-asserted-by":"crossref","first-page":"7170","DOI":"10.3390\/ijms21197170","article-title":"Oxidative stress and microglial response in retinitis Pigmentosa","volume":"21","author":"Murakami","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0290","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jphs.2014.12.005","article-title":"Role of sigma-1 receptors in neurodegenerative diseases","volume":"127","author":"Nguyen","year":"2015","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0295","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/s12974-022-02576-x","article-title":"The cytokine IL-27 reduces inflammation and protects photoreceptors in a mouse model of retinal degeneration","volume":"19","author":"Nortey","year":"2022","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.nbd.2024.106436_bb0300","doi-asserted-by":"crossref","first-page":"13839","DOI":"10.1096\/fj.202000044RR","article-title":"Intravitreal administration of adalimumab delays retinal degeneration in rd10 mice","volume":"34","author":"Olivares-Gonz\u00e1lez","year":"2020","journal-title":"FASEB J."},{"key":"10.1016\/j.nbd.2024.106436_bb0305","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.3390\/antiox10071033","article-title":"Nutraceutical supplementation ameliorates visual function, retinal degeneration, and redox status in rd10 mice","volume":"10","author":"Olivares-Gonz\u00e1lez","year":"2021","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.nbd.2024.106436_bb0310","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3390\/antiox12010098","article-title":"An SPM-enriched marine oil supplement shifted microglia polarization toward M2, ameliorating retinal degeneration in rd10 mice","volume":"12","author":"Olivares-Gonz\u00e1lez","year":"2022","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.nbd.2024.106436_bb0315","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1172\/JCI200421686","article-title":"Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells","volume":"114","author":"Otani","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2024.106436_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.113993","article-title":"Fructus Lycii and salvia miltiorrhiza Bunge extract alleviate retinitis pigmentosa through Nrf2\/HO-1 signaling pathway","volume":"273","author":"Ou","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.nbd.2024.106436_bb0325","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1167\/iovs.07-1622","article-title":"AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation","volume":"49","author":"Pang","year":"2008","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0330","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/mt.2010.273","article-title":"Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa","volume":"19","author":"Pang","year":"2011","journal-title":"Mol. Ther."},{"key":"10.1016\/j.nbd.2024.106436_bb0335","doi-asserted-by":"crossref","first-page":"8139","DOI":"10.1523\/JNEUROSCI.5200-13.2014","article-title":"Suppression of microglial activation is neuroprotective in a mouse model of human retinitis pigmentosa","volume":"34","author":"Peng","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0340","doi-asserted-by":"crossref","first-page":"4644","DOI":"10.1167\/iovs.12-9611","article-title":"Long-term characterization of retinal degeneration in rd1 and rd10 mice using spectral domain optical coherence tomography","volume":"53","author":"Pennesi","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0345","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1111\/ejn.12196","article-title":"Cone survival and preservation of visual acuity in an animal model of retinal degeneration","volume":"37","author":"Piano","year":"2013","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0350","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2017.306","article-title":"p75NTR antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa","volume":"8","author":"Plat\u00f3n-Corchado","year":"2017","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.nbd.2024.106436_bb0355","doi-asserted-by":"crossref","first-page":"6775","DOI":"10.1523\/JNEUROSCI.3102-20.2021","article-title":"Inhibition of epigenetic modifiers LSD1 and HDAC1 blocks rod photoreceptor death in mouse models of retinitis Pigmentosa","volume":"41","author":"Popova","year":"2021","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0360","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20220776","article-title":"Vision rescue via unconstrained in vivo prime editing in degenerating neural retinas","volume":"220","author":"Qin","year":"2023","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.nbd.2024.106436_bb0365","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0165197","article-title":"Progesterone attenuates microglial-driven retinal degeneration and stimulates protective Fractalkine-CX3CR1 signaling","volume":"11","author":"Roche","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2024.106436_bb0370","doi-asserted-by":"crossref","first-page":"43067","DOI":"10.1038\/srep43067","article-title":"Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina","volume":"7","author":"Roche","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2024.106436_bb0375","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/glia.23243","article-title":"Microglial-induced M\u00fcller cell gliosis is attenuated by progesterone in a mouse model of retinitis pigmentosa","volume":"66","author":"Roche","year":"2018","journal-title":"Glia"},{"key":"10.1016\/j.nbd.2024.106436_bb0380","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.1167\/iovs.19-27246","article-title":"Norgestrel, a progesterone analogue, promotes significant long-term neuroprotection of cone photoreceptors in a mouse model of retinal disease","volume":"60","author":"Roche","year":"2019","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0385","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1111\/ejn.13604","article-title":"Pro-survival redox signalling in progesterone-mediated retinal neuroprotection","volume":"46","author":"Ruiz Lopez","year":"2017","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0390","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s13024-018-0251-y","article-title":"Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa","volume":"13","author":"S\u00e1nchez-Cruz","year":"2018","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.nbd.2024.106436_bb0395","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/s41419-022-04839-0","article-title":"Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa","volume":"13","author":"S\u00e1nchez-Cruz","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.nbd.2024.106436_bb0400","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.phrs.2015.06.019","article-title":"Neuroprotective actions of progesterone in an in vivo model of retinitis pigmentosa","volume":"99","author":"S\u00e1nchez-Vallejo","year":"2015","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0405","doi-asserted-by":"crossref","first-page":"3104","DOI":"10.1172\/JCI85193","article-title":"Reprogramming M\u00fcller glia via in vivo cell fusion regenerates murine photoreceptors","volume":"126","author":"Sanges","year":"2016","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2024.106436_bb0410","doi-asserted-by":"crossref","first-page":"18706","DOI":"10.1073\/pnas.1007644107","article-title":"Inhibition of ceramide biosynthesis preserves photoreceptor structure and function in a mouse model of retinitis pigmentosa","volume":"107","author":"Strettoi","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2024.106436_bb0415","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.omtn.2023.02.011","article-title":"In vivo base editing rescues photoreceptors in a mouse model of retinitis pigmentosa","volume":"31","author":"Su","year":"2023","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"10.1016\/j.nbd.2024.106436_bb0420","doi-asserted-by":"crossref","unstructured":"Sukkar, B., Oktay, L., Sahaboglu, A., Moayedi, A., Zenouri, S., Al-Maghout, T., Cant\u00f3, A., Miranda, M., Durdagi, S., Hosseinzadeh, Z., 2023. Inhibition of altered Orai1 channels in M\u00fcller cells protects photoreceptors in retinal degeneration. Glia 2023 (published online ahead of print). 71, 2511-2526.","DOI":"10.1002\/glia.24429"},{"key":"10.1016\/j.nbd.2024.106436_bb0425","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12886-020-01765-7","article-title":"Ferulic acid attenuates microglia-mediated neuroinflammation in retinal degeneration","volume":"21","author":"Sun","year":"2021","journal-title":"BMC Ophthalmol."},{"key":"10.1016\/j.nbd.2024.106436_bb0430","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.ymthe.2022.12.012","article-title":"Photoreceptor laminin drives differentiation of human pluripotent stem cells to photoreceptor progenitors that partially restore retina function","volume":"31","author":"Tay","year":"2023","journal-title":"Mol. Ther."},{"key":"10.1016\/j.nbd.2024.106436_bb0435","doi-asserted-by":"crossref","first-page":"13972","DOI":"10.1523\/JNEUROSCI.2399-13.2013","article-title":"Block of gap junctions eliminates aberrant activity and restores light responses during retinal degeneration","volume":"33","author":"Toychiev","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0440","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/978-3-319-75402-4_45","article-title":"Primary rod and cone degeneration is prevented by HDAC inhibition","volume":"1074","author":"Trifunovi\u0107","year":"2018","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.nbd.2024.106436_bb0445","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1111\/j.1471-4159.2009.06195.x","article-title":"NADPH oxidase plays a central role in cone cell death in retinitis pigmentosa","volume":"110","author":"Usui","year":"2009","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nbd.2024.106436_bb0450","doi-asserted-by":"crossref","first-page":"945","DOI":"10.3389\/fnins.2019.00945","article-title":"Gene editing preserves visual functions in a mouse model of retinal degeneration","volume":"13","author":"Vagni","year":"2019","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0455","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/978-3-030-27378-1_75","article-title":"The resveratrol prodrug JC19 delays retinal degeneration in rd10 mice","volume":"1185","author":"Vald\u00e9s-S\u00e1nchez","year":"2019","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.nbd.2024.106436_bb0460","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2023.106771","article-title":"Sigma-1 receptor and seizures","volume":"191","author":"Vavers","year":"2023","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0465","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.preteyeres.2018.03.005","article-title":"Non-syndromic retinitis pigmentosa","volume":"66","author":"Verbakel","year":"2018","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0470","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.exer.2010.11.012","article-title":"Focus on molecules: proinsulin in the eye: precursor or pioneer?","volume":"101","author":"Vergara","year":"2012","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0475","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.1038\/s41598-019-40215-3","article-title":"Poly ADP ribosylation and extracellular vesicle activity in rod photoreceptor degeneration","volume":"9","author":"Vidal-Gil","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2024.106436_bb0480","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/978-3-030-27378-1_76","article-title":"A novel mechanism of sigma 1 receptor neuroprotection: modulation of miR-214-3p","volume":"1185","author":"Wang","year":"2019","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.nbd.2024.106436_bb0485","first-page":"E3764","article-title":"Activation of the molecular chaperone, sigma 1 receptor, preserves cone function in a murine model of inherited retinal degeneration","volume":"113","author":"Wang","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2024.106436_bb0490","doi-asserted-by":"crossref","first-page":"4397","DOI":"10.1167\/iovs.19-27709","article-title":"Activation of sigma 1 receptor extends survival of cones and improves visual acuity in a murine model of retinitis Pigmentosa","volume":"60","author":"Wang","year":"2019","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0495","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.freeradbiomed.2019.02.001","article-title":"The molecular chaperone sigma 1 receptor mediates rescue of retinal cone photoreceptor cells via modulation of NRF2","volume":"134","author":"Wang","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.nbd.2024.106436_bb0500","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1167\/iovs.61.13.3","article-title":"Comparison of sigma 1 receptor ligands SA4503 and PRE084 to ++-Pentazocine in the rd10 mouse model of RP","volume":"61","author":"Wang","year":"2020","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0505","doi-asserted-by":"crossref","first-page":"7601","DOI":"10.1038\/srep07601","article-title":"Retinal structure and function preservation by polysaccharides of wolfberry in a mouse model of retinal degeneration","volume":"4","author":"Wang","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2024.106436_bb0510","doi-asserted-by":"crossref","first-page":"5287","DOI":"10.1167\/iovs.17-22096","article-title":"Iron-chelating drugs enhance cone photoreceptor survival in a mouse model of retinitis pigmentosa","volume":"58","author":"Wang","year":"2017","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0515","doi-asserted-by":"crossref","first-page":"3294","DOI":"10.1523\/JNEUROSCI.2717-16.2017","article-title":"Tamoxifen provides structural and functional Rescue in Murine Models of photoreceptor degeneration","volume":"37","author":"Wang","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0520","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1080\/15569527.2018.1508153","article-title":"3,5-Dimethoxy-4-hydroxy myricanol ameliorates photoreceptor cell degeneration in Pde6brd10 mouse model","volume":"38","author":"Wang","year":"2019","journal-title":"Cutan. Ocul. Toxicol."},{"key":"10.1016\/j.nbd.2024.106436_bb0525","doi-asserted-by":"crossref","first-page":"4923","DOI":"10.1038\/s41467-023-40655-6","article-title":"AAV-mediated base-editing therapy ameliorates the disease phenotypes in a mouse model of retinitis pigmentosa","volume":"14","author":"Wu","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2024.106436_bb0530","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1111\/ejn.13166","article-title":"The synthetic progesterone Norgestrel is neuroprotective in stressed photoreceptor-like cells and retinal explants, mediating its effects via basic fibroblast growth factor, protein kinase a and glycogen synthase kinase 3 signalling","volume":"43","author":"Wyse Jackson","year":"2016","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106436_bb0535","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.neuropharm.2018.06.027","article-title":"Inhibition of non-NMDA ionotropic glutamate receptors delays the retinal degeneration in rd10 mouse","volume":"139","author":"Xiang","year":"2018","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.nbd.2024.106436_bb0540","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1167\/iovs.61.3.5","article-title":"Comparison of neuroprotective effects of Monomethylfumarate to the sigma 1 receptor ligand ++-Pentazocine in a murine model of retinitis Pigmentosa","volume":"61","author":"Xiao","year":"2020","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0545","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12428","article-title":"Melatonin delays photoreceptor degeneration in a mouse model of autosomal recessive retinitis pigmentosa","volume":"63","author":"Xu","year":"2017","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0550","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1167\/iovs.61.10.25","article-title":"Suppression of cGMP-dependent photoreceptor cytotoxicity with mycophenolate is neuroprotective in murine models of retinitis Pigmentosa","volume":"61","author":"Yang","year":"2020","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.nbd.2024.106436_bb0555","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1186\/s12974-020-01993-0","article-title":"Cyclooxygenase-1 mediates neuroinflammation and neurotoxicity in a mouse model of retinitis pigmentosa","volume":"17","author":"Yang","year":"2020","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.nbd.2024.106436_bb0560","doi-asserted-by":"crossref","first-page":"9554457","DOI":"10.1155\/2023\/9554457","article-title":"Lycium barbarum polysaccharides regulating miR-181\/Bcl-2 decreased autophagy of retinal pigment epithelium with oxidative stress","volume":"2023","author":"Yang","year":"2023","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.nbd.2024.106436_bb0565","doi-asserted-by":"crossref","first-page":"4374087","DOI":"10.1155\/2018\/4374087","article-title":"Lutein and zeaxanthin isomers reduce photoreceptor degeneration in the Pde6brd10 mouse model of retinitis Pigmentosa","volume":"2018","author":"Yu","year":"2018","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.nbd.2024.106436_bb0570","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.exer.2017.07.004","article-title":"Neuroprotective effects of methyl 3,4 dihydroxybenzoate in a mouse model of retinitis pigmentosa","volume":"162","author":"Zhang","year":"2017","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.nbd.2024.106436_bb0575","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1186\/s13287-022-03100-x","article-title":"Mesenchymal stem cell-derived extracellular vesicles protect retina in a mouse model of retinitis pigmentosa by anti-inflammation through miR-146a-Nr4a3 axis","volume":"13","author":"Zhang","year":"2022","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.nbd.2024.106436_bb0580","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.talanta.2017.12.078","article-title":"UPLC-MS\/MS analysis for antioxidant components of Lycii Fructus based on spectrum-effect relationship","volume":"180","author":"Zhang","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.nbd.2024.106436_bb0585","doi-asserted-by":"crossref","first-page":"1059947","DOI":"10.3389\/fimmu.2022.1059947","article-title":"Neuroinflammation in retinitis pigmentosa: therapies targeting the innate immune system","volume":"13","author":"Zhao","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.nbd.2024.106436_bb0590","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/s13287-020-01608-8","article-title":"Protective effects of human iPS-derived retinal pigmented epithelial cells on retinal degenerative disease","volume":"11","author":"Zhu","year":"2020","journal-title":"Stem Cell Res Ther"}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996124000354?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996124000354?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:46:29Z","timestamp":1725583589000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996124000354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":118,"alternative-id":["S0969996124000354"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2024.106436","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Navigating the future of retinitis pigmentosa treatments: A comprehensive analysis of therapeutic approaches in rd10 mice","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2024.106436","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106436"}}