{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T03:02:47Z","timestamp":1793156567083,"version":"4.5.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T00:00:00Z","timestamp":1717632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.nbd.2024.106558","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T19:59:18Z","timestamp":1717790358000},"page":"106558","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["FLNA regulates neuronal maturation by modulating RAC1-Cofilin activity in the developing cortex"],"prefix":"10.1016","volume":"198","author":[{"given":"Antonio","family":"Falace","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lea","family":"Corbieres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catia","family":"Palminha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizia Claudia","family":"Guarnieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabienne","family":"Schaller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Buhler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Tuccari di San Carlo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelie","family":"Montheil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Watrin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Bernard","family":"Manent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Represa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"de Chevigny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Pallesi-Pocachard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2024.106558_bb0005","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/brain\/awh388","article-title":"The role of periventricular nodular heterotopia in epileptogenesis","volume":"128","author":"Aghakhani","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2024.106558_bb0010","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/dvg.22797","article-title":"Generation and characterization of Neurod1-CreER(T2) mouse lines for the study of embryonic and adult neurogenesis","volume":"52","author":"Aprea","year":"2014","journal-title":"Genesis"},{"key":"10.1016\/j.nbd.2024.106558_bb0015","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.cell.2006.12.021","article-title":"Trekking across the brain: the journey of neuronal migration","volume":"128","author":"Ayala","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2024.106558_bb0020","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.3390\/cells10102726","article-title":"Cofilin and actin dynamics: multiple modes of regulation and their impacts in neuronal development and degeneration","volume":"10","author":"Bamburg","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.nbd.2024.106558_bb0025","doi-asserted-by":"crossref","first-page":"4232","DOI":"10.1093\/brain\/awac049","article-title":"Activating RAC1 variants in the switch II region cause a developmental syndrome and alter neuronal morphology","volume":"145","author":"Banka","year":"2022","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2024.106558_bb0030","doi-asserted-by":"crossref","first-page":"37136","DOI":"10.1038\/srep37136","article-title":"Periodic F-actin structures shape the neck of dendritic spines","volume":"6","author":"B\u00e4r","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2024.106558_bb0035","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1146\/annurev.biochem.72.121801.161742","article-title":"Biology of the p21-activated kinases","volume":"72","author":"Bokoch","year":"2003","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.nbd.2024.106558_bb0040","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1111\/ejn.13595","article-title":"Neurobiological bases of autism-epilepsy comorbidity: a focus on excitation\/inhibition imbalance","volume":"47","author":"Bozzi","year":"2018","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0045","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1093\/hmg\/ddr531","article-title":"A glial origin for periventricular nodular heterotopia caused by impaired expression of Filamin-a","volume":"21","author":"Carabalona","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2024.106558_bb0050","first-page":"1029","article-title":"Reelin and cofilin cooperate during the migration of cortical neurons: a quantitative morphological analysis","volume":"143","author":"Chai","year":"2016","journal-title":"Development"},{"key":"10.1016\/j.nbd.2024.106558_bb0055","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/nrn2373","article-title":"Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy","volume":"9","author":"Cingolani","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0060","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3389\/fnsyn.2020.00012","article-title":"The role of Rac GTPase in dendritic spine morphogenesis and memory","volume":"12","author":"Costa","year":"2020","journal-title":"Front. Synaptic. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0065","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000109851","article-title":"Functions of Rac GTPases during neuronal development","volume":"30","author":"de Curtis","year":"2008","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0070","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1093\/brain\/118.5.1273","article-title":"Periventricular and subcortical nodular heterotopia. A study of 33 patients","volume":"118","author":"Dubeau","year":"1995","journal-title":"Brain"},{"issue":"5","key":"10.1016\/j.nbd.2024.106558_bb0075","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/12963","article-title":"Activation of LIM-kinase by Pak1 couples Rac\/Cdc42 GTPase signalling to actin cytoskeletal dynamics","volume":"11","author":"Edwards","year":"1999","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.nbd.2024.106558_bb0080","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1073\/pnas.1316294111","article-title":"TBC1D24 regulates neuronal migration and maturation through modulation of the ARF6-dependent pathway","volume":"111","author":"Falace","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2024.106558_bb0085","doi-asserted-by":"crossref","first-page":"19836","DOI":"10.1073\/pnas.0609628104","article-title":"Filamin a (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis","volume":"103","author":"Feng","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2024.106558_bb0090","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/hmg\/ddn377","article-title":"Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia","volume":"18","author":"Ferland","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2024.106558_bb0095","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1016\/S0896-6273(00)80651-0","article-title":"Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia","volume":"21","author":"Fox","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2024.106558_bb0100","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1176\/appi.neuropsych.11110336","article-title":"Neuropsychiatric disease in patients with periventricular heterotopia","volume":"25","author":"Fry","year":"2013","journal-title":"J. Neuropsychiatr. Clin. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0105","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1073\/pnas.0504777103","article-title":"Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells","volume":"103","author":"Gardel","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2024.106558_bb0110","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/j.neuron.2011.05.021","article-title":"Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses","volume":"70","author":"Gilman","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2024.106558_bb0115","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nm.3090","article-title":"Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression","volume":"19","author":"Golden","year":"2013","journal-title":"Nat. Med."},{"key":"10.1016\/j.nbd.2024.106558_bb0120","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.neuron.2013.04.017","article-title":"Recombinant probes for visualizing endogenous synaptic proteins in living neurons","volume":"78","author":"Gross","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2024.106558_bb0125","doi-asserted-by":"crossref","first-page":"255","DOI":"10.31887\/DCNS.2018.20.4\/ccardoso","article-title":"Disorders of neurogenesis and cortical development","volume":"20","author":"Guarnieri","year":"2018","journal-title":"Dialogues Clin. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0130","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/S1474-4422(14)70040-7","article-title":"Malformations of cortical development: clinical features and genetic causes","volume":"13","author":"Guerrini","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nbd.2024.106558_bb0135","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1093\/hmg\/ddl168","article-title":"Cardiac malformations and midline skeletal defects in mice lacking filamin a","volume":"15","author":"Hart","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2024.106558_bb0140","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/s41439-020-00131-9","article-title":"Hemizygous FLNA variant in West syndrome without periventricular nodular heterotopia","volume":"7","author":"Hiromoto","year":"2020","journal-title":"Hum. Genome. Var."},{"key":"10.1016\/j.nbd.2024.106558_bb0145","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1083\/jcb.201003008","article-title":"Actin in dendritic spines: connecting dynamics to function","volume":"189","author":"Hotulainen","year":"2010","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2024.106558_bb0150","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/nrn2836","article-title":"Branching out: mechanisms of dendritic arborization","volume":"11","author":"Jan","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0155","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/s41467-022-35708-1","article-title":"Filamin a organizes \u03b3-aminobutyric acid type B receptors at the plasma membrane","volume":"14","author":"Jobin","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2024.106558_bb0160","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1002\/wcs.1206","article-title":"The evolution of brains from early mammals to humans","volume":"4","author":"Kaas","year":"2013","journal-title":"Wiley Interdiscip. Rev. Cogn. Sci."},{"key":"10.1016\/j.nbd.2024.106558_bb0165","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1126\/science.290.5494.1113","article-title":"Neuroscience: breaking down scientific barriers to the study of brain and mind","volume":"290","author":"Kandel","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.nbd.2024.106558_bb0170","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1091\/mbc.e09-07-0596","article-title":"Molecular architecture of synaptic actin cytoskeleton in hippocampal neurons reveals a mechanism of dendritic spine morphogenesis","volume":"21","author":"Korobova","year":"2010","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.nbd.2024.106558_bb0175","doi-asserted-by":"crossref","first-page":"10817","DOI":"10.1523\/JNEUROSCI.2569-17.2017","article-title":"Illuminating neural circuits: from molecules to MRI","volume":"37","author":"Lee","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0180","doi-asserted-by":"crossref","first-page":"7672","DOI":"10.1523\/JNEUROSCI.0894-12.2012","article-title":"Filamin a regulates neural progenitor proliferation and cortical size through Wee1-dependent Cdk1 phosphorylation","volume":"32","author":"Lian","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0185","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1093\/cercor\/bhy033","article-title":"Cytoskeletal associated Filamin A and RhoA affect neural progenitor specification during mitosis","volume":"29","author":"Lian","year":"2019","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.nbd.2024.106558_bb0190","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1083\/jcb.201411008","article-title":"KCC2 regulates actin dynamics in dendritic spines via interaction with \u03b2-PIX","volume":"209","author":"Llano","year":"2015","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2024.106558_bb0195","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1146\/annurev-cellbio-100814-125353","article-title":"Generating neuronal diversity in the mammalian cerebral cortex","volume":"31","author":"Lodato","year":"2015","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.nbd.2024.106558_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111722","article-title":"Social deficits via dysregulated Rac1-dependent excitability control of prefrontal cortical neurons and increased GABA\/glutamate ratios","volume":"41","author":"Ma","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.nbd.2024.106558_bb0205","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.semcdb.2022.05.017","article-title":"Mechanical regulation of synapse formation and plasticity","volume":"140","author":"Minegishi","year":"2023","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.nbd.2024.106558_bb0210","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1042\/BJ20130290","article-title":"FilGAP and its close relatives: a mediator of rho-Rac antagonism that regulates cell morphology and migration","volume":"453","author":"Nakamura","year":"2013","journal-title":"Biochem. J."},{"key":"10.1016\/j.nbd.2024.106558_bb0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0004928","article-title":"Molecular basis of filamin A-FilGAP interaction and its impairment in congenital disorders associated with filamin a mutations","volume":"4","author":"Nakamura","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2024.106558_bb0220","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1159\/000516657","article-title":"Dendritic integration dysfunction in neurodevelopmental disorders","volume":"43","author":"Nelson","year":"2021","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0225","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/s12035-012-8265-x","article-title":"Aberrant dendritic excitability: a common pathophysiology in CNS disorders affecting memory?","volume":"45","author":"Nestor","year":"2012","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.nbd.2024.106558_bb0230","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1038\/mp.2011.163","article-title":"Transcriptome profiling of UPF3B\/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability","volume":"17","author":"Nguyen","year":"2012","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.nbd.2024.106558_bb0235","doi-asserted-by":"crossref","first-page":"3013","DOI":"10.1002\/cne.23106","article-title":"Distinct regional and subcellular localization of the actin-binding protein filamin a in the mature rat brain","volume":"520","author":"Noam","year":"2012","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.nbd.2024.106558_bb0240","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1038\/ncb1437","article-title":"FilGAP, a rho- and ROCK-regulated GAP for Rac binds filamin a to control actin remodelling","volume":"8","author":"Ohta","year":"2006","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.nbd.2024.106558_bb0245","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1093\/brain\/awl125","article-title":"Periventricular heterotopia: phenotypic heterogeneity and correlation with Filamin A mutations","volume":"129","author":"Parrini","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2024.106558_bb0250","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.tcb.2008.07.002","article-title":"Convergent CaMK and RacGEF signals control dendritic structure and function","volume":"18","author":"Penzes","year":"2008","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.nbd.2024.106558_bb0255","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1111\/epi.13919","article-title":"Epileptogenic networks in nodular heterotopia: a stereoelectroencephalography study","volume":"58","author":"Pizzo","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.nbd.2024.106558_bb0260","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aan0852","article-title":"Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome","volume":"10","author":"Pyronneau","year":"2017","journal-title":"Sci. Signal."},{"key":"10.1016\/j.nbd.2024.106558_bb0265","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1038\/nrn2719","article-title":"Evolution of the neocortex: a perspective from developmental biology","volume":"10","author":"Rakic","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0270","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.ajhg.2017.08.007","article-title":"RAC1 missense mutations in developmental disorders with diverse phenotypes","volume":"10","author":"Reijnders","year":"2017","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.nbd.2024.106558_bb0275","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0001997","article-title":"Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images","volume":"3","author":"Rodriguez","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2024.106558_bb0280","doi-asserted-by":"crossref","first-page":"3521","DOI":"10.1007\/s00018-015-1941-z","article-title":"ADF\/cofilin: a crucial regulator of synapse physiology and behavior","volume":"72","author":"Rust","year":"2015","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.nbd.2024.106558_bb0285","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1016\/j.celrep.2016.02.047","article-title":"The oxygen sensor PHD2 controls dendritic spines and synapses via modification of Filamin a","volume":"14","author":"Segura","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.nbd.2024.106558_bb0290","article-title":"Filamin a mediated Big2 dependent endocytosis: from apical abscission to periventricular heterotopia","volume":"2","author":"Sheen","year":"2014","journal-title":"Tissue Barr."},{"key":"10.1016\/j.nbd.2024.106558_bb0295","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1093\/hmg\/11.23.2845","article-title":"Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact","volume":"11","author":"Sheen","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2024.106558_bb0300","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1136\/jnnp.2008.162263","article-title":"Bilateral periventricular nodular heterotopia in France: frequency of mutations in FLNA, phenotypic heterogeneity and spectrum of mutations","volume":"80","author":"Sol\u00e9","year":"2009","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.nbd.2024.106558_bb0305","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nn.3947","article-title":"Molecular mechanisms of epilepsy","volume":"18","author":"Staley","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0310","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s12551-011-0042-y","article-title":"Filamin structure, function and mechanics: are altered filamin-mediated force responses associated with human disease?","volume":"3","author":"Sutherland-Smith","year":"2011","journal-title":"Biophys. Rev."},{"key":"10.1016\/j.nbd.2024.106558_bb0315","doi-asserted-by":"crossref","first-page":"6930","DOI":"10.1523\/JNEUROSCI.5395-09.2010","article-title":"Rac1 regulates neuronal polarization through the WAVE complex","volume":"30","author":"Tahirovic","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106558_bb0320","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0896-6273(00)80376-1","article-title":"Regulation of dendritic growth and remodeling by rho, Rac, and Cdc42","volume":"19","author":"Threadgill","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2024.106558_bb0325","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s00401-010-0655-4","article-title":"The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes","volume":"119","author":"Wegiel","year":"2010","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2024.106558_bb0330","first-page":"125","article-title":"Gene mutations in unexplained infantile epileptic encephalopathy: an analysis of 47 cases","volume":"20","author":"Wei","year":"2018","journal-title":"Zhongguo Dang. Dai. Er. Ke. Za. Zhi. Chin."},{"key":"10.1016\/j.nbd.2024.106558_bb0335","doi-asserted-by":"crossref","first-page":"2940","DOI":"10.1002\/1873-3468.12339","article-title":"Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways","volume":"590","author":"Xiang","year":"2016","journal-title":"FEBS Lett."},{"issue":"393","key":"10.1016\/j.nbd.2024.106558_bb0340","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1038\/31735","article-title":"Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization","volume":"25","author":"Yang","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2024.106558_bb0345","doi-asserted-by":"crossref","first-page":"7254","DOI":"10.1038\/s41598-018-25354-3","article-title":"Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics","volume":"8","author":"Zamboni","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2024.106558_bb0350","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.neuron.2014.09.009","article-title":"MEK-ERK1\/2-dependent FLNA overexpression promotes abnormal dendritic patterning in tuberous sclerosis independent of mTOR","volume":"84","author":"Zhang","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2024.106558_bb0355","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aay0289","article-title":"FilaminA inhibition reduces seizure activity in a mouse model of focal cortical malformations","volume":"12","author":"Zhang","year":"2020","journal-title":"Sci. Transl. Med."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996124001578?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996124001578?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T17:14:44Z","timestamp":1728062084000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996124001578"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":71,"alternative-id":["S0969996124001578"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2024.106558","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"FLNA regulates neuronal maturation by modulating RAC1-Cofilin activity in the developing cortex","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2024.106558","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106558"}}