{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T11:02:34Z","timestamp":1787828554458,"version":"build-2784847793"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T00:00:00Z","timestamp":1727395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020963","name":"Japan Science and Technology Agency Moonshot Research and Development Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.nbd.2024.106686","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T05:58:33Z","timestamp":1727675913000},"page":"106686","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Legumain\/asparaginyl endopeptidase-resistant tau fibril fold produces corticobasal degeneration-specific C-terminal tau fragment"],"prefix":"10.1016","volume":"201","author":[{"given":"Daisuke","family":"Taniguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shotaro","family":"Shimonaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Imtiaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montasir","family":"Elahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taku","family":"Hatano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuzuru","family":"Imai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobutaka","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2024.106686_bb0005","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/ana.10793","article-title":"Identification of amino-terminally cleaved tau fragments that distinguish progressive supranuclear palsy from corticobasal degeneration","volume":"55","author":"Arai","year":"2004","journal-title":"Ann. Neurol."},{"issue":"633\u2013644","key":"10.1016\/j.nbd.2024.106686_bb0010","article-title":"Posttranslational modifications mediate the structural diversity of Tauopathy strains","volume":"180","author":"Arakhamia","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2024.106686_bb0015","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1212\/WNL.0b013e31827f0fd1","article-title":"Criteria for the diagnosis of corticobasal degeneration","volume":"80","author":"Armstrong","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.nbd.2024.106686_bb0020","doi-asserted-by":"crossref","first-page":"17495","DOI":"10.1074\/jbc.M112.446070","article-title":"Activation of asparaginyl endopeptidase leads to tau hyperphosphorylation in Alzheimer disease","volume":"288","author":"Basurto-Islas","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2024.106686_bb0025","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/mdc3.12900","article-title":"Pathology-proven Corticobasal degeneration presenting as Richardson\u2019s syndrome","volume":"7","author":"Bayram","year":"2020","journal-title":"Mov Disord Clin Pract."},{"key":"10.1016\/j.nbd.2024.106686_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2019.104518","article-title":"Asparagine endopeptidase cleaves tau at N167 after uptake into microglia","volume":"130","author":"Behrendt","year":"2019","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.nbd.2024.106686_bb0035","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/brain\/awz346","article-title":"Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology","volume":"143","author":"Blennow","year":"2020","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2024.106686_bb0040","doi-asserted-by":"crossref","first-page":"9535","DOI":"10.1073\/pnas.1301175110","article-title":"Brain homogenates from human tauopathies induce tau inclusions in mouse brain","volume":"110","author":"Clavaguera","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2024.106686_bb0045","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s13024-021-00440-9","article-title":"Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model","volume":"16","author":"Clayton","year":"2021","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.nbd.2024.106686_bb0050","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.biochi.2015.09.022","article-title":"Structure and function of legumain in health and disease","volume":"122","author":"Dall","year":"2016","journal-title":"Biochimie"},{"key":"10.1016\/j.nbd.2024.106686_bb0055","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/mds.26370","article-title":"Alpha-synuclein propagation: new insights from animal models","volume":"31","author":"Dehay","year":"2016","journal-title":"Mov. Disord."},{"key":"10.1016\/j.nbd.2024.106686_bb0060","doi-asserted-by":"crossref","first-page":"II6","DOI":"10.1007\/BF03161076","article-title":"Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration","volume":"246 Suppl 2","author":"Dickson","year":"1999","journal-title":"J. Neurol."},{"key":"10.1016\/j.nbd.2024.106686_bb0065","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1093\/jnen\/61.11.935","article-title":"Office of rare diseases neuropathologic criteria for corticobasal degeneration","volume":"61","author":"Dickson","year":"2002","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2024.106686_bb0070","first-page":"1388","article-title":"Widespread cytoskeletal pathology characterizes corticobasal degeneration","volume":"146","author":"Feany","year":"1995","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.nbd.2024.106686_bb0075","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3389\/fnagi.2019.00112","article-title":"Involvement of oligodendrocytes in tau seeding and spreading in Tauopathies","volume":"11","author":"Ferrer","year":"2019","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.nbd.2024.106686_bb0080","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nature23002","article-title":"Cryo-EM structures of tau filaments from Alzheimer\u2019s disease","volume":"547","author":"Fitzpatrick","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2024.106686_bb0085","first-page":"33","article-title":"The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer\u2019s disease","volume":"9","author":"Flores-Rodriguez","year":"2015","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.nbd.2024.106686_bb0090","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s00401-023-02604-x","article-title":"Cell-specific MAPT gene expression is preserved in neuronal and glial tau cytopathologies in progressive supranuclear palsy","volume":"146","author":"Forrest","year":"2023","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2024.106686_bb0095","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3233\/JAD-2003-5201","article-title":"Conformational changes and truncation of tau protein during tangle evolution in Alzheimer\u2019s disease","volume":"5","author":"Garcia-Sierra","year":"2003","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.nbd.2024.106686_bb0100","first-page":"18","article-title":"Propagation of tau aggregates. Mol","volume":"10","author":"Goedert","year":"2017","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2024.106686_bb0105","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/mds.26987","article-title":"Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria","volume":"32","author":"Hoglinger","year":"2017","journal-title":"Mov. Disord."},{"key":"10.1016\/j.nbd.2024.106686_bb0110","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/brain\/awab289","article-title":"Development of a novel tau propagation mouse model endogenously expressing 3 and 4 repeat tau isoforms","volume":"145","author":"Hosokawa","year":"2022","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2024.106686_bb0115","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2021.607303","article-title":"Neuronal and glial distribution of tau protein in the adult rat and monkey","volume":"14","author":"Kanaan","year":"2021","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.nbd.2024.106686_bb0120","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1038\/s12276-020-00494-7","article-title":"Delta-secretase cleavage of tau mediates its pathology and propagation in Alzheimer\u2019s disease","volume":"52","author":"Kang","year":"2020","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.nbd.2024.106686_bb0125","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.neuron.2016.09.055","article-title":"Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo","volume":"92","author":"Kaufman","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2024.106686_bb0130","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s004010050911","article-title":"Astrocytic plaques and tufts of abnormal fibers do not coexist in corticobasal degeneration and progressive supranuclear palsy","volume":"96","author":"Komori","year":"1998","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2024.106686_bb0135","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3389\/fnagi.2020.00096","article-title":"Astroglia and tau: new perspectives","volume":"12","author":"Kovacs","year":"2020","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.nbd.2024.106686_bb0140","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00401-015-1509-x","article-title":"Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy","volume":"131","author":"Kovacs","year":"2016","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2024.106686_bb0145","doi-asserted-by":"crossref","first-page":"3237","DOI":"10.1093\/brain\/aww256","article-title":"Astrogliopathy predominates the earliest stage of corticobasal degeneration pathology","volume":"139","author":"Ling","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2024.106686_bb0150","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/00005072-199601000-00010","article-title":"Validity and reliability of the preliminary NINDS neuropathologic criteria for progressive supranuclear palsy and related disorders","volume":"55","author":"Litvan","year":"1996","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.nbd.2024.106686_bb0155","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1002\/alz.12321","article-title":"Visualization of neurofibrillary tangle maturity in Alzheimer\u2019s disease: a clinicopathologic perspective for biomarker research","volume":"17","author":"Moloney","year":"2021","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.nbd.2024.106686_bb0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00401-011-0910-3","article-title":"National Institute on Aging-Alzheimer\u2019s Association guidelines for the neuropathologic assessment of Alzheimer\u2019s disease: a practical approach","volume":"123","author":"Montine","year":"2012","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2024.106686_bb0165","doi-asserted-by":"crossref","first-page":"11406","DOI":"10.1523\/JNEUROSCI.1230-17.2017","article-title":"Pathological tau strains from human brains recapitulate the diversity of Tauopathies in nontransgenic mouse brain","volume":"37","author":"Narasimhan","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106686_bb0170","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20190783","article-title":"Human tau pathology transmits glial tau aggregates in the absence of neuronal tau","volume":"217","author":"Narasimhan","year":"2020","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.nbd.2024.106686_bb0175","article-title":"Clinical Spectrum of Tauopathies","volume":"13","author":"Olfati","year":"2022","journal-title":"Front. Neurol."},{"key":"10.1016\/j.nbd.2024.106686_bb0180","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3233\/JAD-170959","article-title":"Tau proteolysis in the pathogenesis of Tauopathies: neurotoxic fragments and novel biomarkers","volume":"63","author":"Quinn","year":"2018","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.nbd.2024.106686_bb0185","doi-asserted-by":"crossref","first-page":"6023","DOI":"10.1038\/s41467-022-33348-z","article-title":"Resolving subcellular pH with a quantitative fluorescent lifetime biosensor","volume":"13","author":"Rennick","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2024.106686_bb0190","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2315690121","article-title":"Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes","volume":"121","author":"Rose","year":"2024","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2024.106686_bb0195","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1093\/brain\/awaa376","article-title":"Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons","volume":"144","author":"Ruan","year":"2021","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2024.106686_bb0200","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/j.neuron.2014.04.047","article-title":"Distinct tau prion strains propagate in cells and mice and define different tauopathies","volume":"82","author":"Sanders","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2024.106686_bb0205","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1186\/s40478-019-0831-2","article-title":"N368-tau fragments generated by legumain are detected only in trace amount in the insoluble tau aggregates isolated from AD brain","volume":"7","author":"Schlegel","year":"2019","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.nbd.2024.106686_bb0210","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.1007\/s00018-014-1610-7","article-title":"Transport and diffusion of tau protein in neurons","volume":"71","author":"Scholz","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.nbd.2024.106686_bb0215","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/s41586-021-03911-7","article-title":"Structure-based classification of tauopathies","volume":"598","author":"Shi","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2024.106686_bb0220","doi-asserted-by":"crossref","first-page":"13996","DOI":"10.1074\/jbc.RA120.013271","article-title":"Asparagine residue 368 is involved in Alzheimer\u2019s disease tau strain-specific aggregation","volume":"295","author":"Shimonaka","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.nbd.2024.106686_bb0225","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s00401-015-1503-3","article-title":"Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau","volume":"131","author":"Taniguchi-Watanabe","year":"2016","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2024.106686_bb0230","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1093\/brain\/awab091","article-title":"Human tauopathy-derived tau strains determine the substrates recruited for templated amplification","volume":"144","author":"Tarutani","year":"2021","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2024.106686_bb0235","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1096\/fasebj.7.2.8440407","article-title":"Aminopeptidases: structure and function","volume":"7","author":"Taylor","year":"1993","journal-title":"FASEB J."},{"issue":"712\u2013728","key":"10.1016\/j.nbd.2024.106686_bb0240","article-title":"Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration","volume":"185","author":"Tracy","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2024.106686_bb0245","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.15252\/embj.201796750","article-title":"Protease cleavage site fingerprinting by label-free in-gel degradomics reveals pH-dependent specificity switch of legumain","volume":"36","author":"Vidmar","year":"2017","journal-title":"EMBO J."},{"key":"10.1016\/j.nbd.2024.106686_bb0250","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.1084\/jem.20180539","article-title":"Delta-secretase (AEP) mediates tau-splicing imbalance and accelerates cognitive decline in tauopathies","volume":"215","author":"Wang","year":"2018","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.nbd.2024.106686_bb0255","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1038\/nn.4328","article-title":"Neuronal activity enhances tau propagation and tau pathology in vivo","volume":"19","author":"Wu","year":"2016","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2024.106686_bb0260","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00401-020-02253-4","article-title":"In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics","volume":"141","author":"Xu","year":"2021","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2024.106686_bb0265","doi-asserted-by":"crossref","first-page":"5925","DOI":"10.1038\/s41380-020-0738-0","article-title":"TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading","volume":"26","author":"Xu","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.nbd.2024.106686_bb0270","doi-asserted-by":"crossref","first-page":"14807","DOI":"10.1038\/s41598-022-19085-9","article-title":"Fluorochromized tyramide-glucose oxidase as a multiplex fluorescent tyramide signal amplification system for histochemical analysis","volume":"12","author":"Yamauchi","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2024.106686_bb0275","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/neup.12143","article-title":"Astrocytic inclusions in progressive supranuclear palsy and corticobasal degeneration","volume":"34","author":"Yoshida","year":"2014","journal-title":"Neuropathology"},{"key":"10.1016\/j.nbd.2024.106686_bb0280","article-title":"Tau isoform-driven CBD pathology transmission in oligodendrocytes in humanized tau mice","volume":"11","author":"Zareba-Paslawska","year":"2020","journal-title":"Front. Neurol."},{"key":"10.1016\/j.nbd.2024.106686_bb0285","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1038\/nm.3700","article-title":"Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer\u2019s disease","volume":"20","author":"Zhang","year":"2014","journal-title":"Nat. Med."},{"key":"10.1016\/j.nbd.2024.106686_bb0290","doi-asserted-by":"crossref","first-page":"14740","DOI":"10.1038\/ncomms14740","article-title":"Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer\u2019s disease","volume":"8","author":"Zhang","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2024.106686_bb0295","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/s41586-020-2043-0","article-title":"Novel tau filament fold in corticobasal degeneration","volume":"580","author":"Zhang","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2024.106686_bb0300","doi-asserted-by":"crossref","first-page":"4009","DOI":"10.1111\/ejn.14857","article-title":"Lack of association between LGMN and Alzheimer\u2019s disease in the southern Han Chinese population","volume":"52","author":"Zhang","year":"2020","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2024.106686_bb0305","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s13024-022-00533-z","article-title":"Tauopathies: new perspectives and challenges","volume":"17","author":"Zhang","year":"2022","journal-title":"Mol. Neurodegener."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996124002869?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996124002869?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T19:10:23Z","timestamp":1729797023000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996124002869"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":61,"alternative-id":["S0969996124002869"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2024.106686","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Legumain\/asparaginyl endopeptidase-resistant tau fibril fold produces corticobasal degeneration-specific C-terminal tau fragment","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2024.106686","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106686"}}