{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:59:13Z","timestamp":1788544753900,"version":"build-2803163510"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Korean Health Industry Develepment Institute"},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["RS-2023-00266288"],"award-info":[{"award-number":["RS-2023-00266288"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.nbd.2025.106970","type":"journal-article","created":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T10:55:30Z","timestamp":1748084130000},"page":"106970","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Data-driven, cross-sectional image-based subtyping and staging of brain volumetric changes in Parkinson's disease"],"prefix":"10.1016","volume":"212","author":[{"given":"Gilsoon","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongmok","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Seok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Hyeon","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Whan","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Won","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyoung","family":"Youn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hosung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2025.106970_bb0005","series-title":"Paper Presented at: Proceedings of the 12th Annual Meeting of the Organization for Human Brain Mapping","article-title":"The CIVET image-processing environment: a fully automated comprehensive pipeline for anatomical neuroimaging research","author":"Ad-Dab\u2019bagh","year":"2006"},{"key":"10.1016\/j.nbd.2025.106970_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.softx.2021.100811","article-title":"pySuStaIn: a Python implementation of the subtype and stage inference algorithm","volume":"16","author":"Aksman","year":"2021","journal-title":"SoftwareX"},{"issue":"6","key":"10.1016\/j.nbd.2025.106970_bb0015","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41582-021-00486-9","article-title":"Prodromal Parkinson disease subtypes - key to understanding heterogeneity","volume":"17","author":"Berg","year":"2021","journal-title":"Nat. Rev. Neurol."},{"issue":"2","key":"10.1016\/j.nbd.2025.106970_bb0020","doi-asserted-by":"crossref","first-page":"455","DOI":"10.3233\/JPD-202481","article-title":"The \u03b1-Synuclein origin and connectome model (SOC model) of Parkinson\u2019s disease: explaining motor asymmetry, non-motor phenotypes, and cognitive decline","volume":"11","author":"Borghammer","year":"2021","journal-title":"J. Parkinsons Dis."},{"issue":"s2","key":"10.1016\/j.nbd.2025.106970_bb0025","doi-asserted-by":"crossref","first-page":"S281","DOI":"10.3233\/JPD-191721","article-title":"Brain-first versus gut-first Parkinson\u2019s disease: a hypothesis","volume":"9","author":"Borghammer","year":"2019","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.nbd.2025.106970_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2021.105557","article-title":"Neuropathological evidence of body-first vs. brain-first Lewy body disease","volume":"161","author":"Borghammer","year":"2021","journal-title":"Neurobiol. Dis."},{"issue":"2","key":"10.1016\/j.nbd.2025.106970_bb0035","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1097\/00004728-199403000-00005","article-title":"Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space","volume":"18","author":"Collins","year":"1994","journal-title":"J. Comput. Assist. Tomogr."},{"key":"10.1016\/j.nbd.2025.106970_bb0040","doi-asserted-by":"crossref","first-page":"689","DOI":"10.3389\/fneur.2020.00689","article-title":"Future perspectives on the relevance of auditory markers in prodromal Parkinson\u2019s disease","volume":"11","author":"De Groote","year":"2020","journal-title":"Front. Neurol."},{"issue":"2","key":"10.1016\/j.nbd.2025.106970_bb0045","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1365-2990.2011.01203.x","article-title":"Neuropathological analysis of brainstem cholinergic and catecholaminergic nuclei in relation to rapid eye movement (REM) sleep behaviour disorder","volume":"38","author":"Dugger","year":"2012","journal-title":"Neuropathol. Appl. Neurobiol."},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0050","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/nan.12501","article-title":"Differential insular cortex subregional vulnerability to \u03b1-synuclein pathology in Parkinson\u2019s disease and dementia with Lewy bodies","volume":"45","author":"Fathy","year":"2019","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.nbd.2025.106970_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2020.102374","article-title":"Progressive brain atrophy and clinical evolution in Parkinson\u2019s disease","volume":"28","author":"Filippi","year":"2020","journal-title":"NeuroImage Clin."},{"key":"10.1016\/j.nbd.2025.106970_bb0060","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2022.1053591","article-title":"BDNF rs10501087, rs1491850 and rs11030094 polymorphisms associated with delayed progression in early-stage Parkinson\u2019s disease","volume":"13","author":"Fischer","year":"2022","journal-title":"Front. Neurol."},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0065","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1016\/j.neuroimage.2012.01.062","article-title":"An event-based model for disease progression and its application in familial Alzheimer\u2019s disease and Huntington\u2019s disease","volume":"60","author":"Fonteijn","year":"2012","journal-title":"NeuroImage"},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0070","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/s41392-023-01588-0","article-title":"Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets","volume":"8","author":"Gao","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0075","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/ejn.14094","article-title":"The clinical heterogeneity of Parkinson\u2019s disease and its therapeutic implications","volume":"49","author":"Greenland","year":"2019","journal-title":"Eur. J. Neurosci."},{"issue":"10","key":"10.1016\/j.nbd.2025.106970_bb0080","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1093\/brain\/awaa238","article-title":"Brain-first versus body-first Parkinson\u2019s disease: a multimodal imaging case-control study","volume":"143","author":"Horsager","year":"2020","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2025.106970_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2022.105626","article-title":"Clinical and imaging evidence of brain-first and body-first Parkinson\u2019s disease","volume":"164","author":"Horsager","year":"2022","journal-title":"Neurobiol. Dis."},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0090","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","article-title":"Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: a clinico-pathological study of 100 cases","volume":"55","author":"Hughes","year":"1992","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"6","key":"10.1016\/j.nbd.2025.106970_bb0095","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/j.neuron.2013.12.003","article-title":"Biomarker modeling of Alzheimer\u2019s disease","volume":"80","author":"Jack","year":"2013","journal-title":"Neuron"},{"issue":"15","key":"10.1016\/j.nbd.2025.106970_bb0100","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1001\/jama.284.15.1931","article-title":"Pramipexole vs levodopa as initial treatment for Parkinson disease: a randomized controlled trial. Parkinson study group","volume":"284","year":"2000","journal-title":"JAMA"},{"issue":"10","key":"10.1016\/j.nbd.2025.106970_bb0105","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1212\/WNL.40.10.1529","article-title":"Variable expression of Parkinson\u2019s disease: a base-line analysis of the DATATOP cohort. The Parkinson Study Group","volume":"40","author":"Jankovic","year":"1990","journal-title":"Neurology"},{"issue":"9","key":"10.1016\/j.nbd.2025.106970_bb0110","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1002\/mds.20513","article-title":"Clinical characteristics in early Parkinson\u2019s disease in a Central California population-based study","volume":"20","author":"Kang","year":"2005","journal-title":"Mov. Disord."},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0115","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.neuroimage.2005.03.036","article-title":"Automated 3-D extraction and evaluation of the inner and outer cortical surfaces using a Laplacian map and partial volume effect classification","volume":"27","author":"Kim","year":"2005","journal-title":"Neuroimage"},{"issue":"18","key":"10.1016\/j.nbd.2025.106970_bb0120","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1212\/WNL.0b013e318253d5dd","article-title":"Functional reorganization of sensorimotor cortex in early Parkinson disease","volume":"78","author":"Kojovic","year":"2012","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.nbd.2025.106970_bb0125","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1177\/0891988708316855","article-title":"Brief screening for mild cognitive impairment in elderly outpatient clinic: validation of the Korean version of the Montreal cognitive assessment","volume":"21","author":"Lee","year":"2008","journal-title":"J. Geriatr. Psychiatry Neurol."},{"issue":"4","key":"10.1016\/j.nbd.2025.106970_bb0130","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/j.neuroimage.2006.10.041","article-title":"An unbiased iterative group registration template for cortical surface analysis","volume":"34","author":"Lyttelton","year":"2007","journal-title":"Neuroimage"},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0135","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1006\/nimg.1999.0534","article-title":"Automated 3-D extraction of inner and outer surfaces of cerebral cortex from MRI","volume":"12","author":"MacDonald","year":"2000","journal-title":"NeuroImage"},{"issue":"5\u20136","key":"10.1016\/j.nbd.2025.106970_bb0140","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s00429-010-0262-0","article-title":"Saliency, switching, attention and control: a network model of insula function","volume":"214","author":"Menon","year":"2010","journal-title":"Brain Struct. Funct."},{"issue":"7","key":"10.1016\/j.nbd.2025.106970_bb0145","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/mds.10473","article-title":"The Unified Parkinson's Disease Rating Scale (UPDRS): status and recommendations","volume":"18","author":"Movement Disorder Society Task Force on Rating Scales for Parkinson's Disease","year":"2003","journal-title":"Mov. Disord."},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0150","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1093\/brain\/awaa461","article-title":"Sequence of clinical and neurodegeneration events in Parkinson\u2019s disease progression","volume":"144","author":"Oxtoby","year":"2021","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2025.106970_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2021.118140","article-title":"White matter hyperintensities segmentation using the ensemble U-net with multi-scale highlighting foregrounds","volume":"237","author":"Park","year":"2021","journal-title":"NeuroImage"},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0160","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.neuroimage.2011.02.046","article-title":"A Bayesian model of shape and appearance for subcortical brain segmentation","volume":"56","author":"Patenaude","year":"2011","journal-title":"Neuroimage"},{"issue":"22","key":"10.1016\/j.nbd.2025.106970_bb0165","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1212\/WNL.0000000000000483","article-title":"Initial cognitive decline is associated with cortical thinning in early Parkinson disease","volume":"82","author":"Pereira","year":"2014","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.nbd.2025.106970_bb0170","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1002\/mds.25037","article-title":"A single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study","volume":"27","author":"Postuma","year":"2012","journal-title":"Mov. Disord."},{"issue":"11","key":"10.1016\/j.nbd.2025.106970_bb0175","doi-asserted-by":"crossref","first-page":"3702","DOI":"10.1093\/brain\/awae303","article-title":"Delineating three distinct spatiotemporal patterns of brain atrophy in Parkinson\u2019s disease","volume":"147","author":"Sakato","year":"2024","journal-title":"Brain"},{"issue":"4","key":"10.1016\/j.nbd.2025.106970_bb0180","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1046\/j.1468-1331.2003.00611.x","article-title":"Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson\u2019s disease","volume":"10","author":"Schaafsma","year":"2003","journal-title":"Eur. J. Neurol."},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0185","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/mdc3.12921","article-title":"Levodopa equivalent dose conversion factors: an updated proposal including opicapone and safinamide","volume":"7","author":"Schade","year":"2020","journal-title":"Mov. Disord. Clin. Pract."},{"issue":"50","key":"10.1016\/j.nbd.2025.106970_bb0190","doi-asserted-by":"crossref","first-page":"9878","DOI":"10.1523\/JNEUROSCI.1138-17.2019","article-title":"The salience network: a neural system for perceiving and responding to homeostatic demands","volume":"39","author":"Seeley","year":"2019","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0195","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1109\/42.668698","article-title":"A nonparametric method for automatic correction of intensity nonuniformity in MRI data","volume":"17","author":"Sled","year":"1998","journal-title":"IEEE Trans. Med. Imaging"},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0200","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/hbm.10062","article-title":"Fast robust automated brain extraction","volume":"17","author":"Smith","year":"2002","journal-title":"Hum. Brain Mapp."},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0205","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.neuroimage.2004.05.007","article-title":"Fast and robust parameter estimation for statistical partial volume models in brain MRI","volume":"23","author":"Tohka","year":"2004","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0210","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/nimg.2001.0978","article-title":"Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain","volume":"15","author":"Tzourio-Mazoyer","year":"2002","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0215","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s00401-015-1485-1","article-title":"Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies","volume":"131","author":"Uchihara","year":"2016","journal-title":"Acta Neuropathol."},{"issue":"12","key":"10.1016\/j.nbd.2025.106970_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.mcpro.2023.100673","article-title":"Synaptic involvement of the human amygdala in Parkinson\u2019s disease","volume":"22","author":"Villar-Conde","year":"2023","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.nbd.2025.106970_bb0225","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/2051-5960-1-2","article-title":"The prion hypothesis in Parkinson\u2019s disease: Braak to the future","volume":"1","author":"Visanji","year":"2013","journal-title":"Acta Neuropathol. Commun."},{"issue":"5","key":"10.1016\/j.nbd.2025.106970_bb0230","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/s41591-021-01309-6","article-title":"Four distinct trajectories of tau deposition identified in Alzheimer\u2019s disease","volume":"27","author":"Vogel","year":"2021","journal-title":"Nat. Med."},{"issue":"12","key":"10.1016\/j.nbd.2025.106970_bb0235","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1002\/acn3.51905","article-title":"Brain olfactory-related atrophy in isolated rapid eye movement sleep behavior disorder","volume":"10","author":"Woo","year":"2023","journal-title":"Ann. Clin. Transl. Neurol."},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0240","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/s41531-024-00730-1","article-title":"Disease progression in proposed brain-first and body-first Parkinson\u2019s disease subtypes","volume":"10","author":"Xu","year":"2024","journal-title":"NPJ Parkinson\u2019s Dis."},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0245","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/s41467-017-02416-0","article-title":"Network connectivity determines cortical thinning in early Parkinson\u2019s disease progression","volume":"9","author":"Yau","year":"2018","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.nbd.2025.106970_bb0250","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1152\/jn.00338.2011","article-title":"The organization of the human cerebral cortex estimated by intrinsic functional connectivity","volume":"106","author":"Yeo","year":"2011","journal-title":"J. Neurophysiol."},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0255","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3233\/JPD-223542","article-title":"Extra-basal ganglia brain structures are related to motor reserve in Parkinson\u2019s disease","volume":"13","author":"Youn","year":"2023","journal-title":"J. Parkinsons Dis."},{"issue":"Pt 9","key":"10.1016\/j.nbd.2025.106970_bb0260","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1093\/brain\/awu176","article-title":"A data-driven model of biomarker changes in sporadic Alzheimer\u2019s disease","volume":"137","author":"Young","year":"2014","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0265","doi-asserted-by":"crossref","first-page":"4273","DOI":"10.1038\/s41467-018-05892-0","article-title":"Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with subtype and stage inference","volume":"9","author":"Young","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2025.106970_bb0270","doi-asserted-by":"crossref","DOI":"10.3389\/frai.2021.613261","article-title":"Ordinal SuStaIn: subtype and stage inference for clinical scores, visual ratings, and other ordinal data","volume":"4","author":"Young","year":"2021","journal-title":"Front. Artif. Intell."},{"issue":"8","key":"10.1016\/j.nbd.2025.106970_bb0275","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1136\/jnnp-2012-304126","article-title":"Cortical thinning is associated with disease stages and dementia in Parkinson\u2019s disease","volume":"84","author":"Zarei","year":"2013","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"1","key":"10.1016\/j.nbd.2025.106970_bb0280","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/s41531-023-00556-3","article-title":"Two distinct trajectories of clinical and neurodegeneration events in Parkinson\u2019s disease","volume":"9","author":"Zhou","year":"2023","journal-title":"NPJ Parkinsons Dis."},{"key":"10.1016\/j.nbd.2025.106970_bb0285","series-title":"Paper Presented at: International Conference on Medical Image Computing and Computer-Assisted Intervention","article-title":"Automatic quantification of MS lesions in 3D MRI brain data sets: validation of INSECT","author":"Zijdenbos","year":"1998"}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096999612500186X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096999612500186X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T14:16:01Z","timestamp":1753107361000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S096999612500186X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":57,"alternative-id":["S096999612500186X"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2025.106970","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Data-driven, cross-sectional image-based subtyping and staging of brain volumetric changes in Parkinson's disease","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2025.106970","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106970"}}