{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T01:24:37Z","timestamp":1784769877017,"version":"3.55.0"},"reference-count":166,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003787","name":"Hebei Provincial Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.nbd.2025.107006","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T19:35:46Z","timestamp":1749843346000},"page":"107006","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Role of Tropomodulins in brain physiology and pathology"],"prefix":"10.1016","volume":"213","author":[{"given":"Chuan","family":"Hong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaopeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixuan","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Zhong","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guofen","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0005","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/j.neuron.2017.10.032","article-title":"Alcohol and the brain: neuronal molecular targets, synapses, and circuits","volume":"96","author":"Abrahao","year":"2017","journal-title":"Neuron"},{"issue":"40","key":"10.1016\/j.nbd.2025.107006_bb0010","doi-asserted-by":"crossref","first-page":"28466","DOI":"10.1074\/jbc.274.40.28466","article-title":"Identification of a novel tropomodulin isoform, skeletal tropomodulin, that caps actin filament pointed ends in fast skeletal muscle","volume":"274","author":"Almenar-Queralt","year":"1999","journal-title":"J. Biol. Chem."},{"issue":"9","key":"10.1016\/j.nbd.2025.107006_bb0015","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a008763","article-title":"Metabolic stress in autophagy and cell death pathways","volume":"4","author":"Altman","year":"2012","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.nbd.2025.107006_bb0020","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.abb.2017.12.005","article-title":"Characterizing interaction forces between actin and proteins of the tropomodulin family reveals the presence of the N-terminal actin-binding site in leiomodin","volume":"638","author":"Arslan","year":"2018","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.nbd.2025.107006_bb0025","doi-asserted-by":"crossref","first-page":"37136","DOI":"10.1038\/srep37136","article-title":"Periodic F-actin structures shape the neck of dendritic spines","volume":"6","author":"Bar","year":"2016","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0030","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1080\/10253890500489395","article-title":"Cortico-amygdala circuits: role in the conditioned stress response","volume":"8","author":"Berretta","year":"2005","journal-title":"Stress"},{"issue":"43","key":"10.1016\/j.nbd.2025.107006_bb0035","doi-asserted-by":"crossref","first-page":"27092","DOI":"10.18632\/oncotarget.25491","article-title":"Favorable prognostic role of tropomodulins in neuroblastoma","volume":"9","author":"Bettinsoli","year":"2018","journal-title":"Oncotarget"},{"issue":"9","key":"10.1016\/j.nbd.2025.107006_bb0040","doi-asserted-by":"crossref","first-page":"3987","DOI":"10.1096\/fj.13-246009","article-title":"Phosphorylation of tropomodulin1 contributes to the regulation of actin filament architecture in cardiac muscle","volume":"28","author":"Bliss","year":"2014","journal-title":"FASEB J."},{"issue":"12","key":"10.1016\/j.nbd.2025.107006_bb0045","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1007\/s11064-007-9388-8","article-title":"Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity","volume":"32","author":"Bolognani","year":"2007","journal-title":"Neurochem. Res."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0050","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/nar\/gkp863","article-title":"Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets","volume":"38","author":"Bolognani","year":"2010","journal-title":"Nucleic Acids Res."},{"issue":"10244","key":"10.1016\/j.nbd.2025.107006_bb0055","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0140-6736(20)31179-X","article-title":"Stroke","volume":"396","author":"Campbell","year":"2020","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0060","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1083\/jcb.136.6.1307","article-title":"Actin depolymerizing factor (ADF\/cofilin) enhances the rate of filament turnover: implication in actin-based motility","volume":"136","author":"Carlier","year":"1997","journal-title":"J. Cell Biol."},{"issue":"6651","key":"10.1016\/j.nbd.2025.107006_bb0065","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1126\/science.adg6812","article-title":"Structures of the free and capped ends of the actin filament","volume":"380","author":"Carman","year":"2023","journal-title":"Science"},{"issue":"Suppl. 9","key":"10.1016\/j.nbd.2025.107006_bb0070","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/epi.12034","article-title":"Regulators of synaptic transmission: roles in the pathogenesis and treatment of epilepsy","volume":"53","author":"Casillas-Espinosa","year":"2012","journal-title":"Epilepsia"},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0075","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1002\/cne.10581","article-title":"Ultrastructural features of sprouted mossy fiber synapses in kindled and kainic acid-treated rats","volume":"458","author":"Cavazos","year":"2003","journal-title":"J. Comp. Neurol."},{"issue":"16","key":"10.1016\/j.nbd.2025.107006_bb0080","doi-asserted-by":"crossref","first-page":"3053","DOI":"10.1007\/s00018-016-2214-1","article-title":"Organization and dynamics of the actin cytoskeleton during dendritic spine morphological remodeling","volume":"73","author":"Chazeau","year":"2016","journal-title":"Cell. Mol. Life Sci."},{"issue":"7\u20138","key":"10.1016\/j.nbd.2025.107006_bb0085","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.neuint.2006.11.008","article-title":"Upregulation of dihydropyrimidinase-related protein 2, spectrin alpha II chain, heat shock cognate protein 70 pseudogene 1 and tropomodulin 2 after focal cerebral ischemia in rats--a proteomics approach","volume":"50","author":"Chen","year":"2007","journal-title":"Neurochem. Int."},{"issue":"1\u20132","key":"10.1016\/j.nbd.2025.107006_bb0090","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0378-1119(00)00327-9","article-title":"Genomic organization of mouse and human erythrocyte tropomodulin genes encoding the pointed end capping protein for the actin filaments","volume":"256","author":"Chu","year":"2000","journal-title":"Gene"},{"issue":"19","key":"10.1016\/j.nbd.2025.107006_bb0095","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21197017","article-title":"Mapping TRPM7 function by NS8593","volume":"21","author":"Chubanov","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"26","key":"10.1016\/j.nbd.2025.107006_bb0100","doi-asserted-by":"crossref","first-page":"10732","DOI":"10.1073\/pnas.1018132108","article-title":"Wnt7a signaling promotes dendritic spine growth and synaptic strength through ca(2)(+)\/calmodulin-dependent protein kinase II","volume":"108","author":"Ciani","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2025.107006_bb0105","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.abb.2016.04.006","article-title":"Tropomyosin-binding properties modulate competition between tropomodulin isoforms","volume":"600","author":"Colpan","year":"2016","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.nbd.2025.107006_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2020.105179","article-title":"Epigenetic principles underlying epileptogenesis and epilepsy syndromes","volume":"148","author":"Conboy","year":"2021","journal-title":"Neurobiol. Dis."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0115","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1006\/geno.1999.6061","article-title":"Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs","volume":"63","author":"Cox","year":"2000","journal-title":"Genomics"},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1044-7431(03)00025-3","article-title":"Mice lacking Tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory","volume":"23","author":"Cox","year":"2003","journal-title":"Mol. Cell. Neurosci."},{"issue":"9","key":"10.1016\/j.nbd.2025.107006_bb0125","article-title":"HuD regulates mRNA-circRNA-miRNA networks in the mouse striatum linked to neuronal development and drug addiction","volume":"10","author":"Dell\u2019Orco","year":"2021","journal-title":"Biology (Basel)"},{"key":"10.1016\/j.nbd.2025.107006_bb0130","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1146\/annurev.biophys.37.032807.125912","article-title":"Mediation, modulation, and consequences of membrane-cytoskeleton interactions","volume":"37","author":"Doherty","year":"2008","journal-title":"Annu. Rev. Biophys."},{"issue":"9624","key":"10.1016\/j.nbd.2025.107006_bb0135","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1016\/S0140-6736(08)60694-7","article-title":"Stroke","volume":"371","author":"Donnan","year":"2008","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0140","first-page":"943","article-title":"Effect of mutations imitating the phosphorylation by TRPM7 kinase on the function of the N-terminal domain of tropomodulin","volume":"53","author":"Dorovkov","year":"2008","journal-title":"Biofizika"},{"issue":"12","key":"10.1016\/j.nbd.2025.107006_bb0145","first-page":"1520","article-title":"Natural history of Huntington disease","volume":"70","author":"Dorsey","year":"2013","journal-title":"JAMA Neurol."},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0150","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.ejcb.2010.10.014","article-title":"Tropomodulins are negative regulators of neurite outgrowth","volume":"90","author":"Fath","year":"2011","journal-title":"Eur. J. Cell Biol."},{"issue":"2","key":"10.1016\/j.nbd.2025.107006_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.03.059","article-title":"Enhancing WNT signaling restores cortical neuronal spine maturation and synaptogenesis in Tbr1 mutants","volume":"31","author":"Fazel Darbandi","year":"2020","journal-title":"Cell Rep."},{"issue":"11","key":"10.1016\/j.nbd.2025.107006_bb0160","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.tcb.2003.09.007","article-title":"Tropomodulins: life at the slow end","volume":"13","author":"Fischer","year":"2003","journal-title":"Trends Cell Biol."},{"issue":"2","key":"10.1016\/j.nbd.2025.107006_bb0165","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1083\/jcb.200209057","article-title":"Pointed-end capping by tropomodulin3 negatively regulates endothelial cell motility","volume":"161","author":"Fischer","year":"2003","journal-title":"J. Cell Biol."},{"issue":"47","key":"10.1016\/j.nbd.2025.107006_bb0170","doi-asserted-by":"crossref","first-page":"36454","DOI":"10.1074\/jbc.M606315200","article-title":"Tropomodulin 3 binds to actin monomers","volume":"281","author":"Fischer","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"26","key":"10.1016\/j.nbd.2025.107006_bb0175","doi-asserted-by":"crossref","first-page":"12792","DOI":"10.1016\/S0021-9258(18)45276-3","article-title":"Identification and purification of a novel Mr 43,000 tropomyosin-binding protein from human erythrocyte membranes","volume":"262","author":"Fowler","year":"1987","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.nbd.2025.107006_bb0180","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1083\/jcb.111.2.471","article-title":"Tropomodulin: a cytoskeletal protein that binds to the end of erythrocyte tropomyosin and inhibits tropomyosin binding to actin","volume":"111","author":"Fowler","year":"1990","journal-title":"J. Cell Biol."},{"issue":"2","key":"10.1016\/j.nbd.2025.107006_bb0185","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1083\/jcb.120.2.411","article-title":"Tropomodulin is associated with the free (pointed) ends of the thin filaments in rat skeletal muscle","volume":"120","author":"Fowler","year":"1993","journal-title":"J. Cell Biol."},{"issue":"41","key":"10.1016\/j.nbd.2025.107006_bb0190","doi-asserted-by":"crossref","first-page":"40000","DOI":"10.1074\/jbc.M306895200","article-title":"Tropomodulin contains two actin filament pointed end-capping domains","volume":"278","author":"Fowler","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0195","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.celrep.2017.01.025","article-title":"Quantitative map of proteome dynamics during neuronal differentiation","volume":"18","author":"Frese","year":"2017","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0200","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0014-5793(01)02498-X","article-title":"The shapes and sizes of two domains of tropomodulin, the P-end-capping protein of actin-tropomyosin","volume":"498","author":"Fujisawa","year":"2001","journal-title":"FEBS Lett."},{"issue":"8","key":"10.1016\/j.nbd.2025.107006_bb0205","doi-asserted-by":"crossref","first-page":"5646","DOI":"10.1007\/s12035-023-03879-7","article-title":"The axonal actin filament cytoskeleton: structure, function, and relevance to injury and degeneration","volume":"61","author":"Gallo","year":"2024","journal-title":"Mol. Neurobiol."},{"issue":"10","key":"10.1016\/j.nbd.2025.107006_bb0210","doi-asserted-by":"crossref","first-page":"R501","DOI":"10.1016\/j.cub.2021.01.055","article-title":"Tropomodulins","volume":"31","author":"Ghosh","year":"2021","journal-title":"Curr. Biol."},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0215","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202101011R","article-title":"Erythroid differentiation in mouse erythroleukemia cells depends on Tmod3-mediated regulation of actin filament assembly into the erythroblast membrane skeleton","volume":"36","author":"Ghosh","year":"2022","journal-title":"FASEB J."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0220","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1091\/mbc.e13-10-0608","article-title":"Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle","volume":"25","author":"Gokhin","year":"2014","journal-title":"Mol. Biol. Cell"},{"issue":"24","key":"10.1016\/j.nbd.2025.107006_bb0225","first-page":"4351","article-title":"Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle","volume":"142","author":"Gokhin","year":"2015","journal-title":"Development"},{"issue":"2","key":"10.1016\/j.nbd.2025.107006_bb0230","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/jnc.12506","article-title":"Actin dynamics in growth cone motility and navigation","volume":"129","author":"Gomez","year":"2014","journal-title":"J. Neurochem."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0235","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/cm.21304","article-title":"Tropomodulin isoforms utilize specific binding functions to modulate dendrite development","volume":"73","author":"Gray","year":"2016","journal-title":"Cytoskeleton (Hoboken)"},{"key":"10.1016\/j.nbd.2025.107006_bb0240","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.mcn.2017.04.002","article-title":"Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function","volume":"84","author":"Gray","year":"2017","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2025.107006_bb0245","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3389\/fnmol.2018.00357","article-title":"Tropomodulin\u2019s actin-binding abilities are required to modulate dendrite development","volume":"11","author":"Gray","year":"2018","journal-title":"Front. Mol. Neurosci."},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0250","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1016\/S0006-3495(02)75600-2","article-title":"Tropomyosin requires an intact N-terminal coiled coil to interact with tropomodulin","volume":"82","author":"Greenfield","year":"2002","journal-title":"Biophys. J."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0255","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1529\/biophysj.104.051128","article-title":"Structure and tropomyosin binding properties of the N-terminal capping domain of tropomodulin 1","volume":"88","author":"Greenfield","year":"2005","journal-title":"Biophys. J."},{"issue":"6544","key":"10.1016\/j.nbd.2025.107006_bb0260","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/377083a0","article-title":"Requirement of pointed-end capping by tropomodulin to maintain actin filament length in embryonic chick cardiac myocytes","volume":"377","author":"Gregorio","year":"1995","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0265","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.conb.2011.09.009","article-title":"Integrating synaptic plasticity and striatal circuit function in addiction","volume":"22","author":"Grueter","year":"2012","journal-title":"Curr. Opin. Neurobiol."},{"issue":"16","key":"10.1016\/j.nbd.2025.107006_bb0270","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1021\/bi401431k","article-title":"Role of tropomodulin\u2019s leucine rich repeat domain in the formation of neurite-like processes","volume":"53","author":"Guillaud","year":"2014","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0275","doi-asserted-by":"crossref","first-page":"41","DOI":"10.2310\/6650.2001.34089","article-title":"Superoxide dismutase SOD1, encoded on chromosome 21, but not SOD2 is overexpressed in brains of patients with down syndrome","volume":"49","author":"Gulesserian","year":"2001","journal-title":"J. Invest. Med."},{"issue":"10","key":"10.1016\/j.nbd.2025.107006_bb0280","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1038\/s41562-024-01924-6","article-title":"Multiplex cerebrospinal fluid proteomics identifies biomarkers for diagnosis and prediction of Alzheimer\u2019s disease","volume":"8","author":"Guo","year":"2024","journal-title":"Nat. Hum. Behav."},{"issue":"12","key":"10.1016\/j.nbd.2025.107006_bb0285","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/s41582-021-00555-z","article-title":"Neurobehavioural comorbidities of epilepsy: towards a network-based precision taxonomy","volume":"17","author":"Hermann","year":"2021","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.nbd.2025.107006_bb0290","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1146\/annurev-pathol-012615-044216","article-title":"Dendritic spine pathology in neurodegenerative diseases","volume":"11","author":"Herms","year":"2016","journal-title":"Annu. Rev. Pathol."},{"issue":"9","key":"10.1016\/j.nbd.2025.107006_bb0295","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/cm.21280","article-title":"Dendritic spine actin dynamics in neuronal maturation and synaptic plasticity","volume":"73","author":"Hlushchenko","year":"2016","journal-title":"Cytoskeleton (Hoboken)"},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0300","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.neuron.2008.01.013","article-title":"The subspine organization of actin fibers regulates the structure and plasticity of dendritic spines","volume":"57","author":"Honkura","year":"2008","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.nbd.2025.107006_bb0305","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1083\/jcb.200809046","article-title":"Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis","volume":"185","author":"Hotulainen","year":"2009","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.nbd.2025.107006_bb0310","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.1038\/ncomms4263","article-title":"miR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression","volume":"5","author":"Hu","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2025.107006_bb0315","first-page":"466","article-title":"Glutamatergic synaptic plasticity in the mesocorticolimbic system in addiction","volume":"8","author":"van Huijstee","year":"2014","journal-title":"Front. Cell. Neurosci."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0320","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1006\/dbio.1995.1026","article-title":"Cloning of tropomodulin cDNA and localization of gene transcripts during mouse embryogenesis","volume":"167","author":"Ito","year":"1995","journal-title":"Dev. Biol."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0325","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.brainres.2006.04.052","article-title":"Protein expression profile in the striatum of acute methamphetamine-treated rats","volume":"1097","author":"Iwazaki","year":"2006","journal-title":"Brain Res."},{"issue":"6 Pt B","key":"10.1016\/j.nbd.2025.107006_bb0330","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1006\/nbdi.2000.0299","volume":"7","author":"Jaarsma","year":"2000","journal-title":"Neurobiol. Dis."},{"issue":"10","key":"10.1016\/j.nbd.2025.107006_bb0335","doi-asserted-by":"crossref","DOI":"10.3390\/genes12101614","article-title":"Epigenetic regulatory dynamics in models of methamphetamine-use disorder","volume":"12","author":"Jayanthi","year":"2021","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.nbd.2025.107006_bb0340","doi-asserted-by":"crossref","first-page":"29204","DOI":"10.1038\/srep29204","article-title":"Tropomodulin-3 is essential in asymmetric division during mouse oocyte maturation","volume":"6","author":"Jo","year":"2016","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0345","article-title":"RNA-binding protein HuD as a versatile factor in neuronal and non-neuronal systems","volume":"10","author":"Jung","year":"2021","journal-title":"Biology (Basel)"},{"key":"10.1016\/j.nbd.2025.107006_bb0350","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.semcdb.2019.12.003","article-title":"Regulation of actin isoforms in cellular and developmental processes","volume":"102","author":"Kashina","year":"2020","journal-title":"Semin. Cell Dev. Biol."},{"issue":"2","key":"10.1016\/j.nbd.2025.107006_bb0355","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.gene.2015.11.049","article-title":"Mutant SOD1 mediated pathogenesis of amyotrophic lateral sclerosis","volume":"577","author":"Kaur","year":"2016","journal-title":"Gene"},{"key":"10.1016\/j.nbd.2025.107006_bb0360","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.expneurol.2018.01.004","article-title":"Decreased glutathione levels cause overt motor neuron degeneration in hSOD1(WT) over-expressing mice","volume":"302","author":"Killoy","year":"2018","journal-title":"Exp. Neurol."},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0365","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1007\/s10517-016-3438-7","article-title":"Effect of coenzyme Q10 on proteomic profile of rat brain amygdala during acute metabolic stress","volume":"161","author":"Kirbaeva","year":"2016","journal-title":"Bull. Exp. Biol. Med."},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0370","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0004810","article-title":"F- and G-actin concentrations in lamellipodia of moving cells","volume":"4","author":"Koestler","year":"2009","journal-title":"PloS One"},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0375","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1523\/JNEUROSCI.2127-17.2017","article-title":"Abeta mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer\u2019s disease","volume":"38","author":"Kommaddi","year":"2018","journal-title":"J. Neurosci."},{"issue":"18","key":"10.1016\/j.nbd.2025.107006_bb0380","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1089\/ars.2019.7754","article-title":"Glutaredoxin1 diminishes amyloid Beta-mediated oxidation of F-actin and reverses cognitive deficits in an Alzheimer\u2019s disease mouse model","volume":"31","author":"Kommaddi","year":"2019","journal-title":"Antioxid. Redox Signal."},{"issue":"Suppl. 1","key":"10.1016\/j.nbd.2025.107006_bb0385","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1055\/s-0029-1216356","article-title":"Dynamics of neuronal circuits in addiction: reward, antireward, and emotional memory","volume":"42 Suppl 1","author":"Koob","year":"2009","journal-title":"Pharmacopsychiatry"},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0390","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biopsych.2019.05.023","article-title":"Neurobiology of opioid addiction: opponent process, Hyperkatifeia, and negative reinforcement","volume":"87","author":"Koob","year":"2020","journal-title":"Biol. Psychiatry"},{"issue":"11","key":"10.1016\/j.nbd.2025.107006_bb0395","doi-asserted-by":"crossref","first-page":"4997","DOI":"10.1073\/pnas.91.11.4997","article-title":"Down syndrome phenotypes: the consequences of chromosomal imbalance","volume":"91","author":"Korenberg","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"39","key":"10.1016\/j.nbd.2025.107006_bb0400","doi-asserted-by":"crossref","first-page":"12068","DOI":"10.1021\/bi060899i","article-title":"Tropomodulin binds two tropomyosins: a novel model for actin filament capping","volume":"45","author":"Kostyukova","year":"2006","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0405","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.biopsych.2019.05.025","article-title":"The opioid-addicted Tetrapartite synapse","volume":"87","author":"Kruyer","year":"2020","journal-title":"Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0410","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.cub.2019.12.049","article-title":"Tropomodulins control the balance between protrusive and contractile structures by stabilizing actin-tropomyosin filaments","volume":"30","author":"Kumari","year":"2020","journal-title":"Curr. Biol."},{"issue":"8","key":"10.1016\/j.nbd.2025.107006_bb0415","doi-asserted-by":"crossref","DOI":"10.3390\/biom13081237","article-title":"Effects of Tropomodulin 2 on dendritic spine reorganization and dynamics","volume":"13","author":"Kuruba","year":"2023","journal-title":"Biomolecules"},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0420","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.cellsig.2005.07.010","article-title":"Protein kinase C and the regulation of the actin cytoskeleton","volume":"18","author":"Larsson","year":"2006","journal-title":"Cell. Signal."},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0425","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s11064-005-2688-y","article-title":"CDNA microarray analysis of nerve growth factor-regulated gene expression profile in rat PC12 cells","volume":"30","author":"Lee","year":"2005","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.nbd.2025.107006_bb0430","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.conb.2016.04.010","article-title":"Actin cytoskeleton in dendritic spine development and plasticity","volume":"39","author":"Lei","year":"2016","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.nbd.2025.107006_bb0435","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.conb.2020.11.015","article-title":"Actin dynamics in the growth cone: a key player in axon regeneration","volume":"69","author":"Leite","year":"2021","journal-title":"Curr. Opin. Neurobiol."},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0440","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0037999","article-title":"Amygdala 14-3-3zeta as a novel modulator of escalating alcohol intake in mice","volume":"7","author":"Lesscher","year":"2012","journal-title":"PloS One"},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0445","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.0040002","article-title":"Genes and (common) pathways underlying drug addiction","volume":"4","author":"Li","year":"2008","journal-title":"PLoS Comput. Biol."},{"issue":"21","key":"10.1016\/j.nbd.2025.107006_bb0450","doi-asserted-by":"crossref","DOI":"10.3390\/ijms252111787","article-title":"Neuroinflammatory proteins in Huntington\u2019s disease: insights into mechanisms, diagnosis, and therapeutic implications","volume":"25","author":"Li","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0455","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1080\/19490992.2015.1031949","article-title":"Tropomodulin3 as the link between insulin-activated AKT2 and cortical actin remodeling in preparation of GLUT4 exocytosis","volume":"4","author":"Lim","year":"2014","journal-title":"Bioarchitecture"},{"key":"10.1016\/j.nbd.2025.107006_bb0460","doi-asserted-by":"crossref","first-page":"5951","DOI":"10.1038\/ncomms6951","article-title":"Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling","volume":"6","author":"Lim","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2025.107006_bb0465","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.bbrc.2021.04.042","article-title":"Down-regulated in renal cell carcinoma 1 (DRR1) regulates axon outgrowth during hippocampal neuron development","volume":"558","author":"Lu","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0470","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1002\/jnr.23018","article-title":"Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: impact on APE1\/Ref-1\u2019s protein-protein interaction","volume":"90","author":"Mantha","year":"2012","journal-title":"J. Neurosci. Res."},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0475","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.neulet.2009.09.039","article-title":"APE1\/Ref-1 in Alzheimer\u2019s disease: an immunohistochemical study","volume":"466","author":"Marcon","year":"2009","journal-title":"Neurosci. Lett."},{"issue":"10","key":"10.1016\/j.nbd.2025.107006_bb0480","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1038\/nn717","article-title":"Rapid formation and remodeling of postsynaptic densities in developing dendrites","volume":"4","author":"Marrs","year":"2001","journal-title":"Nat. Neurosci."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0485","doi-asserted-by":"crossref","DOI":"10.1093\/braincomms\/fcac305","article-title":"Phosphoproteomic dysregulation in Huntington's disease mice is rescued by environmental enrichment","volume":"4","author":"Mees","year":"2022","journal-title":"Brain Commun."},{"issue":"8","key":"10.1016\/j.nbd.2025.107006_bb0490","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines10081859","article-title":"Post-synapses in the brain: role of dendritic and spine structures","volume":"10","author":"Meldolesi","year":"2022","journal-title":"Biomedicines"},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0495","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1038\/s42003-023-05355-3","article-title":"Methamphetamine-induced region-specific transcriptomic and epigenetic changes in the brain of male rats","volume":"6","author":"Miao","year":"2023","journal-title":"Commun. Biol."},{"issue":"18","key":"10.1016\/j.nbd.2025.107006_bb0500","article-title":"Tmod2 is a regulator of cocaine responses through control of striatal and cortical excitability and drug-induced plasticity","volume":"44","author":"Mitra","year":"2024","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107006_bb0505","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.7","article-title":"Mutations changing tropomodulin affinity for tropomyosin alter neurite formation and extension","volume":"1","author":"Moroz","year":"2013","journal-title":"PeerJ"},{"issue":"14","key":"10.1016\/j.nbd.2025.107006_bb0510","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1182\/blood-2010-02-268458","article-title":"Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton","volume":"116","author":"Moyer","year":"2010","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.nbd.2025.107006_bb0515","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0136607","article-title":"Fluid shear stress upregulates E-Tmod41 via miR-23b-3p and contributes to F-actin cytoskeleton remodeling during erythropoiesis","volume":"10","author":"Mu","year":"2015","journal-title":"PloS One"},{"issue":"11","key":"10.1016\/j.nbd.2025.107006_bb0520","doi-asserted-by":"crossref","first-page":"7047","DOI":"10.1038\/s41380-021-01104-2","article-title":"Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy","volume":"26","author":"Negraes","year":"2021","journal-title":"Mol. Psychiatry"},{"issue":"9","key":"10.1016\/j.nbd.2025.107006_bb0525","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1182\/blood-2017-05-787051","article-title":"Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome","volume":"130","author":"Nowak","year":"2017","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0530","doi-asserted-by":"crossref","DOI":"10.1111\/gbb.12454","article-title":"Neuronal RNA-binding protein HuD regulates addiction-related gene expression and behavior","volume":"17","author":"Oliver","year":"2018","journal-title":"Genes Brain Behav."},{"issue":"48","key":"10.1016\/j.nbd.2025.107006_bb0535","doi-asserted-by":"crossref","first-page":"10271","DOI":"10.1523\/JNEUROSCI.3325-17.2018","article-title":"Tropomodulin isoform-specific regulation of dendrite development and synapse formation","volume":"38","author":"Omotade","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107006_bb0540","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107143","article-title":"Targeting the cytoskeleton as a therapeutic approach to substance use disorders","volume":"202","author":"Pandey","year":"2024","journal-title":"Pharmacol. Res."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0545","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1093\/schbul\/sbab046","article-title":"miR-936 is increased in schizophrenia and inhibits neural development and AMPA receptor-mediated synaptic transmission","volume":"47","author":"Panja","year":"2021","journal-title":"Schizophr. Bull."},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0550","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19051345","article-title":"SOD1 in amyotrophic lateral sclerosis: \u201cambivalent\u201d behavior connected to the disease","volume":"19","author":"Pansarasa","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0555","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1007\/s12551-018-0481-9","article-title":"Multifunctional roles of tropomodulin-3 in regulating actin dynamics","volume":"10","author":"Parreno","year":"2018","journal-title":"Biophys. Rev."},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0560","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.metabol.2011.10.005","article-title":"Metabolic consequences of stress during childhood and adolescence","volume":"61","author":"Pervanidou","year":"2012","journal-title":"Metabolism"},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0565","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1503\/jpn.160189","article-title":"S100A10 identified in a genome-wide gene x cannabis dependence interaction analysis of risky sexual behaviours","volume":"42","author":"Polimanti","year":"2017","journal-title":"J. Psychiatry Neurosci."},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0570","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ejpn.2007.08.010","article-title":"Mental retardation and associated neurological dysfunctions in down syndrome: a consequence of dysregulation in critical chromosome 21 genes and associated molecular pathways","volume":"12","author":"Rachidi","year":"2008","journal-title":"Eur. J. Paediatr. Neurol."},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0575","doi-asserted-by":"crossref","first-page":"482","DOI":"10.7150\/ijms.99159","article-title":"A mechanistic review on toxicity effects of methamphetamine","volume":"22","author":"Ramli","year":"2025","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.nbd.2025.107006_bb0580","doi-asserted-by":"crossref","unstructured":"Roberto, M., D. Kirson, and S. Khom, The Role of the Central Amygdala in Alcohol Dependence. Cold Spring Harb Perspect Med, 2021. vol. 11(2).","DOI":"10.1101\/cshperspect.a039339"},{"key":"10.1016\/j.nbd.2025.107006_bb0585","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3389\/fncel.2013.00103","article-title":"WNT signaling in neuronal maturation and synaptogenesis","volume":"7","author":"Rosso","year":"2013","journal-title":"Front. Cell. Neurosci."},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0590","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.conb.2013.01.027","article-title":"Emerging roles of actin cytoskeleton regulating enzymes in drug addiction: actin or reactin\u2019?","volume":"23","author":"Rothenfluh","year":"2013","journal-title":"Curr. Opin. Neurobiol."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0595","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/ng1718","article-title":"APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy","volume":"38","author":"Rovelet-Lecrux","year":"2006","journal-title":"Nat. Genet."},{"key":"10.1016\/j.nbd.2025.107006_bb0600","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.nbd.2019.01.001","article-title":"Human and rodent temporal lobe epilepsy is characterized by changes in O-GlcNAc homeostasis that can be reversed to dampen epileptiform activity","volume":"124","author":"Sanchez","year":"2019","journal-title":"Neurobiol. Dis."},{"issue":"41","key":"10.1016\/j.nbd.2025.107006_bb0605","doi-asserted-by":"crossref","first-page":"17213","DOI":"10.1073\/pnas.1103318108","article-title":"Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition","volume":"108","author":"Schmidt","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.nbd.2025.107006_bb0610","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.brainresbull.2022.10.019","article-title":"Regulation of actin filament assembly and disassembly in growth cone motility and axon guidance","volume":"192","author":"Schneider","year":"2023","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.nbd.2025.107006_bb0615","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.175001","article-title":"Cytoskeleton saga: its regulation in normal physiology and modulation in neurodegenerative disorders","volume":"925","author":"Sen","year":"2022","journal-title":"Eur. J. Pharmacol."},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0620","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.freeradbiomed.2004.05.019","article-title":"Aberrant neuronal and mitochondrial proteins in hippocampus of transgenic mice overexpressing human cu\/Zn superoxide dismutase 1","volume":"37","author":"Shin","year":"2004","journal-title":"Free Radic. Biol. Med."},{"issue":"2","key":"10.1016\/j.nbd.2025.107006_bb0625","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/jnc.12313","article-title":"Actin filaments and microtubules in dendritic spines","volume":"126","author":"Shirao","year":"2013","journal-title":"J. Neurochem."},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0630","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.neuron.2014.10.024","article-title":"Dendritic structural degeneration is functionally linked to cellular hyperexcitability in a mouse model of Alzheimer\u2019s disease","volume":"84","author":"Siskova","year":"2014","journal-title":"Neuron"},{"issue":"20","key":"10.1016\/j.nbd.2025.107006_bb0635","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20205034","article-title":"Ischemia\/reperfusion injury revisited: an overview of the latest pharmacological strategies","volume":"20","author":"Soares","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"26","key":"10.1016\/j.nbd.2025.107006_bb0640","doi-asserted-by":"crossref","first-page":"16357","DOI":"10.1074\/jbc.M114.599399","article-title":"Mammalian target of rapamycin (mTOR) tagging promotes dendritic branch variability through the capture of Ca2+\/calmodulin-dependent protein kinase II alpha (CaMKIIalpha) mRNAs by the RNA-binding protein HuD","volume":"290","author":"Sosanya","year":"2015","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0645","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1186\/s13041-021-00832-4","article-title":"Transcriptomic profiling of high- and low-spiking regions reveals novel epileptogenic mechanisms in focal cortical dysplasia type II patients","volume":"14","author":"Srivastava","year":"2021","journal-title":"Mol. Brain"},{"key":"10.1016\/j.nbd.2025.107006_bb0650","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/2371970","article-title":"Regulation of the postsynaptic compartment of excitatory synapses by the actin cytoskeleton in health and its disruption in disease","volume":"2016","author":"Stefen","year":"2016","journal-title":"Neural Plast."},{"key":"10.1016\/j.nbd.2025.107006_bb0655","doi-asserted-by":"crossref","first-page":"11097","DOI":"10.1038\/ncomms11097","article-title":"Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular mg(2+) homeostasis and cytoskeletal architecture","volume":"7","author":"Stritt","year":"2016","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.nbd.2025.107006_bb0660","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1182\/blood-2013-03-492710","article-title":"Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver","volume":"123","author":"Sui","year":"2014","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0665","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.jprot.2011.01.009","article-title":"A gel-based proteomic method reveals several protein pathway abnormalities in fetal down syndrome brain","volume":"74","author":"Sun","year":"2011","journal-title":"J. Proteomics"},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0670","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1016\/S0021-9258(18)45926-1","article-title":"Molecular cloning and characterization of human fetal liver tropomodulin. A tropomyosin-binding protein","volume":"267","author":"Sung","year":"1992","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0675","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1432-1033.1992.tb16787.x","article-title":"Tropomodulin binding to tropomyosins. Isoform-specific differences in affinity and stoichiometry","volume":"205","author":"Sussman","year":"1992","journal-title":"Eur. J. Biochem."},{"issue":"1\u20132","key":"10.1016\/j.nbd.2025.107006_bb0680","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0165-3806(94)90088-4","article-title":"Neural tropomodulin: developmental expression and effect of seizure activity","volume":"80","author":"Sussman","year":"1994","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.nbd.2025.107006_bb0685","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104725","article-title":"Neuronal actin cytoskeleton gain of function in the human brain","volume":"95","author":"Szigeti","year":"2023","journal-title":"EBioMedicine"},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0690","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1111\/j.1369-1600.2012.00470.x","article-title":"Neuroplasticity, axonal guidance and micro-RNA genes are associated with morphine self-administration behavior","volume":"18","author":"Tapocik","year":"2013","journal-title":"Addict. Biol."},{"issue":"12","key":"10.1016\/j.nbd.2025.107006_bb0695","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/s41582-021-00574-w","article-title":"Autonomic manifestations of epilepsy: emerging pathways to sudden death?","volume":"17","author":"Thijs","year":"2021","journal-title":"Nat. Rev. Neurol."},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0700","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1074\/jbc.M110.186924","article-title":"Identification of residues within tropomodulin-1 responsible for its localization at the pointed ends of the actin filaments in cardiac myocytes","volume":"286","author":"Tsukada","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0705","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s12987-024-00508-w","article-title":"Comparative analysis of hippocampal extracellular space uncovers widely altered peptidome upon epileptic seizure in urethane-anaesthetized rats","volume":"21","author":"Tukacs","year":"2024","journal-title":"Fluids Barriers CNS"},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0710","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s12035-014-9032-y","article-title":"TRPM7 regulates axonal outgrowth and maturation of primary hippocampal neurons","volume":"53","author":"Turlova","year":"2016","journal-title":"Mol. Neurobiol."},{"issue":"10","key":"10.1016\/j.nbd.2025.107006_bb0715","doi-asserted-by":"crossref","first-page":"8320","DOI":"10.1007\/s12035-024-04053-3","article-title":"Role of cytoskeletal elements in regulation of synaptic functions: implications toward Alzheimer\u2019s disease and phytochemicals-based interventions","volume":"61","author":"Verma","year":"2024","journal-title":"Mol. Neurobiol."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0720","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.neuron.2012.03.005","article-title":"Growth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane","volume":"73","author":"Vitriol","year":"2012","journal-title":"Neuron"},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0725","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.cell.2015.07.046","article-title":"The brain on drugs: from reward to addiction","volume":"162","author":"Volkow","year":"2015","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0730","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1152\/physrev.00014.2018","article-title":"The neuroscience of drug reward and addiction","volume":"99","author":"Volkow","year":"2019","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.nbd.2025.107006_bb0735","first-page":"394","article-title":"The interaction and phosphorylation of tropomodulin by protein kinase Calpha in N\/N 1003A lens epithelial cells","volume":"8","author":"Wagner","year":"2002","journal-title":"Mol. Vis."},{"issue":"Pt 9","key":"10.1016\/j.nbd.2025.107006_bb0740","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1242\/jcs.109.9.2299","article-title":"N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin","volume":"109","author":"Watakabe","year":"1996","journal-title":"J. Cell Sci."},{"issue":"6 Pt 1","key":"10.1016\/j.nbd.2025.107006_bb0745","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1083\/jcb.127.6.1627","article-title":"Tropomodulin caps the pointed ends of actin filaments","volume":"127","author":"Weber","year":"1994","journal-title":"J. Cell Biol."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0750","doi-asserted-by":"crossref","first-page":"20220595","DOI":"10.1515\/biol-2022-0595","article-title":"The altered expression of cytoskeletal and synaptic remodeling proteins during epilepsy","volume":"18","author":"Xin","year":"2023","journal-title":"Open Life Sci"},{"key":"10.1016\/j.nbd.2025.107006_bb0755","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.neuroscience.2024.12.024","article-title":"Unravelling neuroregenerative and neuroprotective roles of Wnt\/beta-catenin pathway in ischemic stroke: insights into molecular mechanisms","volume":"565","author":"Yadava","year":"2025","journal-title":"Neuroscience"},{"issue":"43","key":"10.1016\/j.nbd.2025.107006_bb0760","doi-asserted-by":"crossref","first-page":"33265","DOI":"10.1074\/jbc.M110.144873","article-title":"Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities","volume":"285","author":"Yamashiro","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0765","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/cm.21031","article-title":"Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types","volume":"69","author":"Yamashiro","year":"2012","journal-title":"Cytoskeleton (Hoboken)"},{"issue":"4","key":"10.1016\/j.nbd.2025.107006_bb0770","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s00726-005-0281-y","article-title":"Aberrant expression of cytoskeleton proteins in hippocampus from patients with mesial temporal lobe epilepsy","volume":"30","author":"Yang","year":"2006","journal-title":"Amino Acids"},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0775","first-page":"71","article-title":"Specific expression of E-Tmod (Tmod1) in horizontal cells: implications in neuronal cell mechanics and glaucomatous retina","volume":"6","author":"Yao","year":"2009","journal-title":"Mol. Cell. Biomech."},{"issue":"41","key":"10.1016\/j.nbd.2025.107006_bb0780","doi-asserted-by":"crossref","first-page":"31408","DOI":"10.1074\/jbc.M110.130278","article-title":"Erythrocyte tropomodulin isoforms with and without the N-terminal actin-binding domain","volume":"285","author":"Yao","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0785","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.modgep.2007.08.002","article-title":"Mouse erythrocyte tropomodulin in the brain reported by lacZ knocked-in downstream from the E1 promoter","volume":"8","author":"Yao","year":"2007","journal-title":"Gene Expr. Patterns"},{"key":"10.1016\/j.nbd.2025.107006_bb0790","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.yebeh.2017.10.010","article-title":"Epilepsy is a neurological and a systemic disorder","volume":"78","author":"Yuen","year":"2018","journal-title":"Epilepsy Behav."},{"issue":"3","key":"10.1016\/j.nbd.2025.107006_bb0795","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.bbrc.2007.09.033","article-title":"Induced expression of the transcription of tropomodulin 1 by Wnt5a and characterization of the tropomodulin 1 promoter","volume":"363","author":"Yun","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.nbd.2025.107006_bb0800","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1146\/annurev.neuro.24.1.1071","article-title":"Morphological changes in dendritic spines associated with long-term synaptic plasticity","volume":"24","author":"Yuste","year":"2001","journal-title":"Annu. Rev. Neurosci."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0805","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/nrn1300","article-title":"Genesis of dendritic spines: insights from ultrastructural and imaging studies","volume":"5","author":"Yuste","year":"2004","journal-title":"Nat. Rev. Neurosci."},{"issue":"8","key":"10.1016\/j.nbd.2025.107006_bb0810","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.neuint.2013.03.016","article-title":"Up-regulation of protein tyrosine nitration in methamphetamine-induced neurotoxicity through DDAH\/ADMA\/NOS pathway","volume":"62","author":"Zhang","year":"2013","journal-title":"Neurochem. Int."},{"issue":"9","key":"10.1016\/j.nbd.2025.107006_bb0815","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.biopsych.2020.12.026","article-title":"Amygdala circuit substrates for stress adaptation and adversity","volume":"89","author":"Zhang","year":"2021","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2025.107006_bb0820","doi-asserted-by":"crossref","first-page":"36993","DOI":"10.1038\/srep36993","article-title":"mRNA changes in nucleus accumbens related to methamphetamine addiction in mice","volume":"6","author":"Zhu","year":"2016","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.nbd.2025.107006_bb0825","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.14336\/AD.2022.0331","article-title":"Neuron-targeted knockout of APE1 forces premature cognitive impairment and synaptic dysfunction in adult mice","volume":"13","author":"Zhu","year":"2022","journal-title":"Aging Dis."},{"issue":"1","key":"10.1016\/j.nbd.2025.107006_bb0830","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s13195-024-01558-w","article-title":"Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer\u2019s disease","volume":"16","author":"Haseena","year":"2024","journal-title":"Alzheimers Res. Ther."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996125002220?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996125002220?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T20:46:47Z","timestamp":1758833207000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996125002220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":166,"alternative-id":["S0969996125002220"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2025.107006","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of Tropomodulins in brain physiology and pathology","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2025.107006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"107006"}}