{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T23:03:13Z","timestamp":1775516593370,"version":"3.50.1"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["MA 5806\/2-1"],"award-info":[{"award-number":["MA 5806\/2-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.nbd.2025.107109","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:56:19Z","timestamp":1758588979000},"page":"107109","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Stimulation of Purkinje cell firing reverses early onset spatial navigation deficits in a spinocerebellar ataxia type 6 mouse model"],"prefix":"10.1016","volume":"216","author":[{"given":"Michelle","family":"Gr\u00f6mmke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Schulte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Candy D.C.","family":"Theis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Nonnweiler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie D.","family":"Mark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2025.107109_bb0005","doi-asserted-by":"crossref","first-page":"3791","DOI":"10.1093\/brain\/awz337","article-title":"Action perception recruits the cerebellum and is impaired in patients with spinocerebellar ataxia","volume":"142","author":"Abdelgabar","year":"2019","journal-title":"Brain"},{"key":"10.1016\/j.nbd.2025.107109_bb0010","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1113\/jphysiol.2008.155077","article-title":"Vesicular apparatus, including functional calcium channels, are present in developing rodent optic nerve axons and are required for normal node of Ranvier formation","volume":"586","author":"Alix","year":"2008","journal-title":"J. Physiol."},{"key":"10.1016\/j.nbd.2025.107109_bb0015","doi-asserted-by":"crossref","first-page":"7249","DOI":"10.1523\/JNEUROSCI.6341-09.2010","article-title":"KCa channels as therapeutic targets in episodic ataxia type-2","volume":"30","author":"Alvi\u00f1a","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0020","doi-asserted-by":"crossref","first-page":"5163","DOI":"10.1073\/pnas.0700293104","article-title":"Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand","volume":"104","author":"Armbruster","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2025.107109_bb0025","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/1526-968X(200011\/12)28:3\/4<93::AID-GENE10>3.0.CO;2-W","article-title":"Cre recombinase expression in cerebellar Purkinje cells","volume":"28","author":"Barski","year":"2000","journal-title":"Genesis"},{"key":"10.1016\/j.nbd.2025.107109_bb0030","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0365-23.2023","article-title":"Mild deficits in fear learning: evidence from humans and mice with cerebellar cortical degeneration","volume":"11","author":"Batsikadze","year":"2024","journal-title":"eNeuro"},{"key":"10.1016\/j.nbd.2025.107109_bb0035","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1126\/science.1132915","article-title":"BKCa-Cav channel complexes mediate rapid and localized Ca2+\u2212activated K+ signaling","volume":"314","author":"Berkefeld","year":"2006","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.nbd.2025.107109_bb0040","doi-asserted-by":"crossref","first-page":"3807","DOI":"10.1093\/hmg\/ddac135","article-title":"Cerebellar contribution to threat probability in a SCA6 mouse model","volume":"31","author":"Bohne","year":"2022","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2025.107109_bb0045","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.expneurol.2005.10.020","article-title":"Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury","volume":"197","author":"Brody","year":"2006","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2025.107109_bb0050","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1038\/nn1532","article-title":"Spatial navigation impairment in mice lacking cerebellar LTD: a motor adaptation deficit?","volume":"8","author":"Burgui\u00e8re","year":"2005","journal-title":"Nat. Neurosci."},{"issue":"1","key":"10.1016\/j.nbd.2025.107109_bb0055","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1113\/jphysiol.2005.103770","article-title":"Kinetic, pharmacological and activity-dependent separation of two Ca2+ signaling pathways mediated by type 1 metabotropic glutamate receptors in rat Purkinje neurons","volume":"573","author":"Canepari","year":"2006","journal-title":"J. Physiol."},{"key":"10.1016\/j.nbd.2025.107109_bb0060","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.neuron.2008.09.005","article-title":"Calcium channel regulation and presynaptic plasticity","volume":"59","author":"Catterall","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2025.107109_bb0065","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1756-6606-7-17","article-title":"Optimization of AAV expression cassettes to improve packaging capacity and transgene expression in neurons","volume":"7","author":"Choi","year":"2014","journal-title":"Mol. Brain"},{"key":"10.1016\/j.nbd.2025.107109_bb0070","article-title":"Cerebellar Purkinje cell stripe patterns reveal a differential vulnerability and resistance to cell loss during normal aging in mice","author":"Donofrio","year":"2025","journal-title":"bioRxiv"},{"key":"10.1016\/j.nbd.2025.107109_bb0075","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.expneurol.2012.04.015","article-title":"Disruption of Purkinje cell function prior to huntingtin accumulation and cell loss in an animal model of Huntington disease","volume":"236","author":"Dougherty","year":"2012","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.nbd.2025.107109_bb0080","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/978-3-319-71779-1_7","article-title":"Spinocerebellar corrected Ataxia type 6: molecular mechanisms and calcium channel genetics","volume":"1049","author":"Du","year":"2018","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.nbd.2025.107109_bb0085","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.cell.2013.05.059","article-title":"Second Cistron in CACNA1A gene encodes a transcription factor mediating cerebellar development and SCA6","volume":"154","author":"Du","year":"2013","journal-title":"Cell"},{"issue":"6","key":"10.1016\/j.nbd.2025.107109_bb0090","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1152\/jn.00913.2015","article-title":"In vivo analysis of cerebellar Purkinje cell activity in SCA2 transgenic mouse model","volume":"115","author":"Egorova","year":"2016","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.nbd.2025.107109_bb0095","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1080\/00207454.2017.1377198","article-title":"Spinocerebellar ataxia: a critical review of cognitive and socio-cognitive deficits","volume":"128","author":"Giocondo","year":"2018","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0100","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1007\/s00415-003-0258-2","article-title":"The cerebellum and cognition. Intellectual function in spinocerebellar ataxia type 6 (SCA6)","volume":"250","author":"Globas","year":"2003","journal-title":"J. Neurol."},{"key":"10.1016\/j.nbd.2025.107109_bb0105","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1002\/mds.22288","article-title":"Early symptoms in spinocerebellar ataxia type 1, 2, 3, and 6","volume":"23","author":"Globas","year":"2008","journal-title":"Movement Disorders: Off. J. Movement Disorder Soc."},{"key":"10.1016\/j.nbd.2025.107109_bb0110","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1002\/ana.410420616","article-title":"Spinocerebellar ataxia type 6: gaze-evoked and vertical nystagmus, Purkinje cell degeneration, and variable age of onset","volume":"42","author":"Gomez","year":"1997","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nbd.2025.107109_bb0115","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0166-4328(05)80119-6","article-title":"Dissociation of spatial navigation and visual guidance performance in Purkinje cell degeneration (pcd) mutant mice","volume":"47","author":"Goodlett","year":"1992","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.nbd.2025.107109_bb0120","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0006-8993(86)91018-8","article-title":"Focal axonal swellings in rat cerebellar Purkinje cells during normal development","volume":"363","author":"Gravel","year":"1986","journal-title":"Brain Res."},{"key":"10.1016\/j.nbd.2025.107109_bb0125","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1016\/j.celrep.2015.08.022","article-title":"Calcium-activated potassium channels at nodes of ranvier secure axonal spike propagation","volume":"12","author":"Gr\u00fcndemann","year":"2015","journal-title":"Cell Rep."},{"key":"10.1016\/j.nbd.2025.107109_bb0130","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1093\/hmg\/dds427","article-title":"Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2","volume":"22","author":"Hansen","year":"2013","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.nbd.2025.107109_bb0135","doi-asserted-by":"crossref","first-page":"7082","DOI":"10.1523\/JNEUROSCI.3778-14.2015","article-title":"BK channels localize to the paranodal junction and regulate action potentials in myelinated axons of cerebellar Purkinje cells","volume":"35","author":"Hirono","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0140","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.neuron.2005.02.012","article-title":"Increased noise level of purkinje cell activities minimizes impact of their modulation during sensorimotor control","volume":"45","author":"Hoebeek","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2025.107109_bb0145","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1152\/jn.1996.75.5.1806","article-title":"Comparison of discharge variability in vitro and in vivo in cat visual cortex neurons","volume":"75","author":"Holt","year":"1996","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.nbd.2025.107109_bb0150","doi-asserted-by":"crossref","first-page":"11795","DOI":"10.1523\/JNEUROSCI.0905-11.2011","article-title":"Aminopyridines correct early dysfunction and delay neurodegeneration in a mouse model of spinocerebellar ataxia type 1","volume":"31","author":"Hourez","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0155","doi-asserted-by":"crossref","first-page":"4146","DOI":"10.1093\/cercor\/bhu132","article-title":"Interaction between hippocampus and cerebellum crus I in sequence-based but not place-based navigation","volume":"25","author":"Igl\u00f3i","year":"2015","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.nbd.2025.107109_bb0160","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0094-15.2015","article-title":"Rapid onset of motor deficits in a mouse model of spinocerebellar ataxia type 6 precedes late cerebellar degeneration","volume":"2","author":"Jayabal","year":"2015","journal-title":"eNeuro"},{"key":"10.1016\/j.nbd.2025.107109_bb0165","doi-asserted-by":"crossref","first-page":"29489","DOI":"10.1038\/srep29489","article-title":"4-aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6","volume":"6","author":"Jayabal","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nbd.2025.107109_bb0170","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jns.2008.03.018","article-title":"Prefrontal hypoperfusion and cognitive dysfunction correlates in spinocerebellar ataxia type 6","volume":"271","author":"Kawai","year":"2008","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.nbd.2025.107109_bb0175","doi-asserted-by":"crossref","first-page":"8432","DOI":"10.1523\/JNEUROSCI.23-23-08432.2003","article-title":"Cerebellar loops with motor cortex and prefrontal cortex of a nonhuman primate","volume":"23","author":"Kelly","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0180","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1111\/j.0953-816X.2004.03319.x","article-title":"Immunocytochemical localization of the alpha 1A subunit of the P\/Q-type calcium channel in the rat cerebellum","volume":"19","author":"Kulik","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0185","doi-asserted-by":"crossref","first-page":"4129","DOI":"10.1038\/s41467-021-24390-4","article-title":"Purkinje cell axonal swellings enhance action potential fidelity and cerebellar function","volume":"12","author":"Lang-Ouellette","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2025.107109_bb0190","doi-asserted-by":"crossref","first-page":"248","DOI":"10.3389\/fncel.2016.00248","article-title":"Transient developmental Purkinje cell axonal torpedoes in healthy and ataxic mouse cerebellum","volume":"10","author":"Ljungberg","year":"2016","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0195","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s12311-014-0556-5","article-title":"Torpedo formation and Purkinje cell loss: modeling their relationship in cerebellar disease","volume":"13","author":"Louis","year":"2014","journal-title":"Cerebellum (London, England)"},{"key":"10.1016\/j.nbd.2025.107109_bb0200","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.neulet.2006.09.007","article-title":"Dissociation of grey and white matter reduction in spinocerebellar ataxia type 3 and 6: a voxel-based morphometry study","volume":"408","author":"Lukas","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.nbd.2025.107109_bb0205","first-page":"5765","article-title":"Cognitive impairments in patients with spinocerebellar ataxia types 1, 2 and 3 are positively correlated to the clinical severity of ataxia symptoms","volume":"7","author":"Ma","year":"2014","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.nbd.2025.107109_bb0210","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jneumeth.2015.06.022","article-title":"Diagnostic tools for evaluating the impact of focal axonal swellings arising in neurodegenerative diseases and\/or traumatic brain injury","volume":"253","author":"Maia","year":"2015","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.nbd.2025.107109_bb0215","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1080\/01616412.1980.11739567","article-title":"The fine structure of the axonal torpedo in Purkinje cells of the human cerebellum","volume":"1","author":"Mann","year":"1980","journal-title":"Neurol. Res."},{"key":"10.1016\/j.nbd.2025.107109_bb0220","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/S0006-3495(91)82179-8","article-title":"Effect of geometrical irregularities on propagation delay in axonal trees","volume":"60","author":"Manor","year":"1991","journal-title":"Biophys. J."},{"key":"10.1016\/j.nbd.2025.107109_bb0225","doi-asserted-by":"crossref","first-page":"8882","DOI":"10.1523\/JNEUROSCI.0891-15.2015","article-title":"Spinocerebellar ataxia type 6 protein aggregates cause deficits in motor learning and cerebellar plasticity","volume":"35","author":"Mark","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0230","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1046\/j.1460-9568.2003.02921.x","article-title":"The cerebellum and spatial ability: dissection of motor and cognitive components with a mouse model system","volume":"18","author":"Martin","year":"2003","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0235","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0896-6273(95)90155-8","article-title":"Calcium control of transmitter release at a cerebellar synapse","volume":"15","author":"Mintz","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2025.107109_bb0240","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0165-0270(84)90007-4","article-title":"Developments of a water-maze procedure for studying spatial learning in the rat","volume":"11","author":"Morris","year":"1984","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.nbd.2025.107109_bb0245","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S0092-8674(00)81373-2","article-title":"Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4","volume":"87","author":"Ophoff","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2025.107109_bb0250","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.1002\/hbm.23568","article-title":"Resting-state functional connectivity and cognitive dysfunction correlations in spinocerebelellar ataxia type 6 (SCA6)","volume":"38","author":"Pereira","year":"2017","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.nbd.2025.107109_bb0255","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.cell.2014.09.014","article-title":"CRISPR-Cas9 knockin mice for genome editing and cancer modeling","volume":"159","author":"Platt","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2025.107109_bb0260","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3389\/fncir.2013.00035","article-title":"The cerebellum: a new key structure in the navigation system","volume":"7","author":"Rochefort","year":"2013","journal-title":"Front. Neural Circuits"},{"key":"10.1016\/j.nbd.2025.107109_bb0265","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s004010050787","article-title":"Neuropathological and molecular studies of spinocerebellar ataxia type 6 (SCA6)","volume":"95","author":"Sasaki","year":"1998","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2025.107109_bb0270","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/s002340050571","article-title":"Spinocerebellar ataxia type 6: MRI of three Japanese patients","volume":"40","author":"Satoh","year":"1998","journal-title":"Neuroradiology"},{"key":"10.1016\/j.nbd.2025.107109_bb0275","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0000485","article-title":"Regular patterns in cerebellar Purkinje cell simple spike trains","volume":"2","author":"Shin","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.nbd.2025.107109_bb0280","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1016\/j.neuroimage.2011.08.065","article-title":"Functional topography of the cerebellum for motor and cognitive tasks: an fMRI study","volume":"59","author":"Stoodley","year":"2012","journal-title":"NeuroImage"},{"key":"10.1016\/j.nbd.2025.107109_bb0285","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1038\/s41593-017-0004-1","article-title":"Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice","volume":"20","author":"Stoodley","year":"2017","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0290","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1136\/jnnp.2007.119883","article-title":"Cognitive impairment in spinocerebellar ataxia type 6","volume":"79","author":"Suenaga","year":"2008","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.nbd.2025.107109_bb0295","first-page":"444","article-title":"Ultrastructural studies of multiple sclerosis","volume":"20","author":"Suzuki","year":"1969","journal-title":"Lab. Investig.; J. Tech. Meth. Pathol."},{"key":"10.1016\/j.nbd.2025.107109_bb0300","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2021.707857","article-title":"Molecular identity and location influence Purkinje cell vulnerability in autosomal-recessive spastic ataxia of Charlevoix-Saguenay mice","volume":"15","author":"Toscano M\u00e1rquez","year":"2021","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0305","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.ijdevneu.2004.06.003","article-title":"Exposure to 3,4-methylenedioxymethamphetamine (MDMA) on postnatal days 11-20 induces reference but not working memory deficits in the Morris water maze in rats: implications of prior learning","volume":"22","author":"Vorhees","year":"2004","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0310","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/nn1648","article-title":"Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia","volume":"9","author":"Walter","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0315","doi-asserted-by":"crossref","first-page":"11987","DOI":"10.1073\/pnas.0804350105","article-title":"Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant CaV2.1 channels","volume":"105","author":"Watase","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.nbd.2025.107109_bb0320","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.41896","article-title":"Anatomical and physiological foundations of cerebello-hippocampal interaction","volume":"8","author":"Watson","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.nbd.2025.107109_bb0325","doi-asserted-by":"crossref","first-page":"6403","DOI":"10.1523\/JNEUROSCI.15-10-06403.1995","article-title":"Immunochemical identification and subcellular distribution of the alpha 1A subunits of brain calcium channels","volume":"15","author":"Westenbroek","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0330","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1046\/j.1460-9568.2002.02171.x","article-title":"Characterization of large conductance Ca2+\u2212activated K+ channels in cerebellar Purkinje neurons","volume":"16","author":"Womack","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0335","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1523\/JNEUROSCI.23-07-02600.2003","article-title":"Somatic and dendritic small-conductance calcium-activated potassium channels regulate the output of cerebellar Purkinje neurons","volume":"23","author":"Womack","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2025.107109_bb0340","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s004010000201","article-title":"Morphological Purkinje cell changes in spinocerebellar ataxia type 6","volume":"100","author":"Yang","year":"2000","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.nbd.2025.107109_bb0345","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/ng0197-62","article-title":"Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel","volume":"15","author":"Zhuchenko","year":"1997","journal-title":"Nat. Genet."}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996125003262?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996125003262?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T20:23:14Z","timestamp":1762028594000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996125003262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":69,"alternative-id":["S0969996125003262"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2025.107109","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stimulation of Purkinje cell firing reverses early onset spatial navigation deficits in a spinocerebellar ataxia type 6 mouse model","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2025.107109","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"107109"}}