{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T12:03:41Z","timestamp":1785153821193,"version":"3.55.0"},"reference-count":118,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","award":["RS-2025-25441283"],"award-info":[{"award-number":["RS-2025-25441283"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002560","name":"Soonchunhyang University","doi-asserted-by":"publisher","award":["2026-0009"],"award-info":[{"award-number":["2026-0009"]}],"id":[{"id":"10.13039\/501100002560","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["RS-2025-16066159"],"award-info":[{"award-number":["RS-2025-16066159"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["RS-2026-25472048"],"award-info":[{"award-number":["RS-2026-25472048"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Disease"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.nbd.2026.107367","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T03:54:51Z","timestamp":1774583691000},"page":"107367","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Thalamostriatal circuit as a therapeutic target of alcohol use disorder"],"prefix":"10.1016","volume":"223","author":[{"given":"Hyein","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongseo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiyong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinwoo","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeongseop","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nbd.2026.107367_bb0005","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1146\/annurev.ne.09.030186.002041","article-title":"Parallel organization of functionally segregated circuits linking basal ganglia and cortex","volume":"9","author":"Alexander","year":"1986","journal-title":"Annu. Rev. Neurosci."},{"issue":"25","key":"10.1016\/j.nbd.2026.107367_bb0010","doi-asserted-by":"crossref","first-page":"9424","DOI":"10.1523\/JNEUROSCI.0490-15.2015","article-title":"Role of striatal cholinergic interneurons in set-shifting in the rat","volume":"35","author":"Aoki","year":"2015","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.nbd.2026.107367_bb0015","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.tics.2010.02.001","article-title":"Cortical and basal ganglia contributions to habit learning and automaticity","volume":"14","author":"Ashby","year":"2010","journal-title":"Trends Cogn. Sci."},{"issue":"8","key":"10.1016\/j.nbd.2026.107367_bb0020","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1111\/ejn.15135","article-title":"Striatal cholinergic transmission. Focus on nicotinic receptors\u2019 influence in striatal circuits","volume":"53","author":"Assous","year":"2021","journal-title":"Eur. J. Neurosci."},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0025","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/s41398-023-02337-1","article-title":"Deep brain stimulation of the nucleus accumbens in treatment-resistant alcohol use disorder: a double-blind randomized controlled multi-center trial","volume":"13","author":"Bach","year":"2023","journal-title":"Transl. Psychiatry"},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0030","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1016\/j.brs.2020.10.007","article-title":"Sonication of the anterior thalamus with MRI-guided transcranial focused ultrasound (tFUS) alters pain thresholds in healthy adults: a double-blind, sham-controlled study","volume":"13","author":"Badran","year":"2020","journal-title":"Brain Stimul."},{"key":"10.1016\/j.nbd.2026.107367_bb0035","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/978-3-030-21737-2_6","article-title":"Endocannabinoid system and alcohol abuse disorders","volume":"1162","author":"Basavarajappa","year":"2019","journal-title":"Adv. Exp. Med. Biol."},{"issue":"12","key":"10.1016\/j.nbd.2026.107367_bb0040","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1212\/01.wnl.0000326066.57313.13","article-title":"The midline and intralaminar thalamic nuclei: anatomic and functional specificity and implications in neurologic disease","volume":"71","author":"Benarroch","year":"2008","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.nbd.2026.107367_bb0045","doi-asserted-by":"crossref","DOI":"10.1002\/hbm.70156","article-title":"Relating functional connectivity and alcohol use disorder: a systematic review and derivation of relevance maps for regions and connections","volume":"46","author":"Bottino","year":"2025","journal-title":"Hum. Brain Mapp."},{"issue":"5","key":"10.1016\/j.nbd.2026.107367_bb0050","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.amepre.2011.06.045","article-title":"Economic costs of excessive alcohol consumption in the U.S., 2006","volume":"41","author":"Bouchery","year":"2011","journal-title":"Am. J. Prev. Med."},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0055","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.neuron.2013.04.039","article-title":"The thalamostriatal pathway and cholinergic control of goal-directed action: interlacing new with existing learning in the striatum","volume":"79","author":"Bradfield","year":"2013","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0060","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.biopsych.2012.06.023","article-title":"A critical review of magnetic resonance spectroscopy studies of obsessive-compulsive disorder","volume":"73","author":"Brennan","year":"2013","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0065","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s13643-019-1220-4","article-title":"Long-term effects of alcohol consumption on cognitive function: a systematic review and dose-response analysis of evidence published between 2007 and 2018","volume":"9","author":"Brennan","year":"2020","journal-title":"Syst. Rev."},{"issue":"7","key":"10.1016\/j.nbd.2026.107367_bb0070","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1111\/acer.12447","article-title":"Impaired decision-making under risk in individuals with alcohol dependence","volume":"38","author":"Brevers","year":"2014","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"43","key":"10.1016\/j.nbd.2026.107367_bb0075","doi-asserted-by":"crossref","first-page":"14390","DOI":"10.1523\/JNEUROSCI.2167-10.2010","article-title":"The parafascicular thalamic nucleus concomitantly influences behavioral flexibility and dorsomedial striatal acetylcholine output in rats","volume":"30","author":"Brown","year":"2010","journal-title":"J. Neurosci."},{"issue":"10","key":"10.1016\/j.nbd.2026.107367_bb0085","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1016\/j.biopsych.2021.03.007","article-title":"Deep brain stimulation of the substantia Nigra pars Reticulata for treatment-resistant schizophrenia: a case report","volume":"90","author":"Cascella","year":"2021","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nbd.2026.107367_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2021.108560","article-title":"Optogenetic induction of orbitostriatal long-term potentiation in the dorsomedial striatum elicits a persistent reduction of alcohol-seeking behavior in rats","volume":"191","author":"Cheng","year":"2021","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.nbd.2026.107367_bb0095","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.83627","article-title":"The rostral intralaminar nuclear complex of the thalamus supports striatally mediated action reinforcement","volume":"12","author":"Cover","year":"2023","journal-title":"Elife"},{"issue":"3","key":"10.1016\/j.nbd.2026.107367_bb0100","doi-asserted-by":"crossref","first-page":"875","DOI":"10.3171\/2016.11.JNS16976","article-title":"Noninvasive neuromodulation and thalamic mapping with low-intensity focused ultrasound","volume":"128","author":"Dallapiazza","year":"2018","journal-title":"J. Neurosurg."},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0105","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.brs.2024.07.019","article-title":"Model-based navigation of transcranial focused ultrasound neuromodulation in humans: application to targeting the amygdala and thalamus","volume":"17","author":"Daneshzand","year":"2024","journal-title":"Brain Stimul."},{"issue":"10","key":"10.1016\/j.nbd.2026.107367_bb0110","doi-asserted-by":"crossref","first-page":"3992","DOI":"10.1038\/s41380-022-01677-6","article-title":"Deep brain stimulation of the nucleus accumbens in the treatment of severe alcohol use disorder: a phase I pilot trial","volume":"27","author":"Davidson","year":"2022","journal-title":"Mol. Psychiatry"},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0115","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1038\/s41467-021-22260-7","article-title":"Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum","volume":"12","author":"de Kloet","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2026.107367_bb0125","article-title":"Common and distinct drug cue reactivity patterns associated with cocaine and heroin: an fMRI meta-analysis","volume":"2","author":"Dejoie","year":"2024","journal-title":"Imaging Neurosci. (Camb)"},{"issue":"14","key":"10.1016\/j.nbd.2026.107367_bb0130","doi-asserted-by":"crossref","first-page":"5274","DOI":"10.1073\/pnas.85.14.5274","article-title":"Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats","volume":"85","author":"Di Chiara","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"3","key":"10.1016\/j.nbd.2026.107367_bb0135","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.neuron.2018.09.052","article-title":"The Thalamostriatal projections contribute to the initiation and execution of a sequence of movements","volume":"100","author":"Diaz-Hernandez","year":"2018","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.nbd.2026.107367_bb0140","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.neuron.2010.06.017","article-title":"Thalamic gating of corticostriatal signaling by cholinergic interneurons","volume":"67","author":"Ding","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2026.107367_bb0145","article-title":"Correlates of post-hospitalization naltrexone adherence for alcohol use disorder","volume":"265","author":"E","year":"2024","journal-title":"Drug Alcohol Depend."},{"issue":"12","key":"10.1016\/j.nbd.2026.107367_bb0150","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.tins.2021.09.006","article-title":"Alcohol and the brain: from genes to circuits","volume":"44","author":"Egervari","year":"2021","journal-title":"Trends Neurosci."},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0155","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.brs.2020.11.007","article-title":"Temporal interference stimulation targets deep brain regions by modulating neural oscillations","volume":"14","author":"Esmaeilpour","year":"2021","journal-title":"Brain Stimul."},{"key":"10.1016\/j.nbd.2026.107367_bb0160","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1146\/annurev-psych-122414-033457","article-title":"Drug addiction: updating actions to habits to compulsions ten years on","volume":"67","author":"Everitt","year":"2016","journal-title":"Annu. Rev. Psychol."},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0165","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1111\/ejn.12271","article-title":"Dorsomedial and dorsolateral striatum exhibit distinct phasic neuronal activity during alcohol self-administration in rats","volume":"38","author":"Fanelli","year":"2013","journal-title":"Eur. J. Neurosci."},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev-neuro-112723-025228","article-title":"Adaptive cost-benefit control fueled by striatal dopamine","volume":"48","author":"Frank","year":"2025","journal-title":"Annu. Rev. Neurosci."},{"issue":"13","key":"10.1016\/j.nbd.2026.107367_bb0175","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1001\/jama.293.13.1617","article-title":"Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial","volume":"293","author":"Garbutt","year":"2005","journal-title":"JAMA"},{"issue":"1655","key":"10.1016\/j.nbd.2026.107367_bb0180","article-title":"Goal-directed learning and obsessive-compulsive disorder","volume":"369","author":"Gillan","year":"2014","journal-title":"Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci."},{"issue":"10","key":"10.1016\/j.nbd.2026.107367_bb0185","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.biopsych.2014.09.008","article-title":"The central amygdala as an integrative hub for anxiety and alcohol use disorders","volume":"77","author":"Gilpin","year":"2015","journal-title":"Biol. Psychiatry"},{"issue":"11","key":"10.1016\/j.nbd.2026.107367_bb0190","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/nrn3119","article-title":"Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications","volume":"12","author":"Goldstein","year":"2011","journal-title":"Nat. Rev. Neurosci."},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0195","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.cell.2017.05.024","article-title":"Noninvasive deep brain stimulation via temporally interfering electric fields","volume":"169","author":"Grossman","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.nbd.2026.107367_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.147011","article-title":"Deep brain stimulation of the infralimbic cortex attenuates cocaine priming-induced reinstatement of drug seeking","volume":"1746","author":"Guercio","year":"2020","journal-title":"Brain Res."},{"issue":"12","key":"10.1016\/j.nbd.2026.107367_bb0205","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1111\/add.14404","article-title":"A systematic review of the next-day effects of heavy alcohol consumption on cognitive performance","volume":"113","author":"Gunn","year":"2018","journal-title":"Addiction"},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0210","doi-asserted-by":"crossref","first-page":"7","DOI":"10.31887\/DCNS.2016.18.1\/shaber","article-title":"Corticostriatal circuitry","volume":"18","author":"Haber","year":"2016","journal-title":"Dialogues Clin. Neurosci."},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0215","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.brs.2014.09.018","article-title":"Chronic unilateral stimulation of the nucleus accumbens at high or low frequencies attenuates relapse to cocaine seeking in an animal model","volume":"8","author":"Hamilton","year":"2015","journal-title":"Brain Stimul."},{"issue":"5","key":"10.1016\/j.nbd.2026.107367_bb0220","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1016\/j.brs.2023.09.021","article-title":"Electrophysiological characteristics of CM-pf in diagnosis and outcome of patients with disorders of consciousness","volume":"16","author":"He","year":"2023","journal-title":"Brain Stimul."},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0225","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.pnpbp.2010.05.025","article-title":"BDNF and GDNF serum levels in alcohol-dependent patients during withdrawal","volume":"34","author":"Heberlein","year":"2010","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"8","key":"10.1016\/j.nbd.2026.107367_bb0230","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.tins.2007.06.006","article-title":"A key role for corticotropin-releasing factor in alcohol dependence","volume":"30","author":"Heilig","year":"2007","journal-title":"Trends Neurosci."},{"issue":"11","key":"10.1016\/j.nbd.2026.107367_bb0235","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.biopsych.2011.07.034","article-title":"Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats","volume":"71","author":"Hermann","year":"2012","journal-title":"Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.nbd.2026.107367_bb0240","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.brs.2021.01.015","article-title":"Accumbens coordinated reset stimulation in mice exhibits ameliorating aftereffects on binge alcohol drinking","volume":"14","author":"Ho","year":"2021","journal-title":"Brain Stimul."},{"issue":"51","key":"10.1016\/j.nbd.2026.107367_bb0245","doi-asserted-by":"crossref","first-page":"eadn2446","DOI":"10.1126\/sciadv.adn2446","article-title":"Dynamic responses of striatal cholinergic interneurons control behavioral flexibility","volume":"10","author":"Huang","year":"2024","journal-title":"Sci. Adv."},{"issue":"2","key":"10.1016\/j.nbd.2026.107367_bb0250","doi-asserted-by":"crossref","first-page":"270","DOI":"10.14309\/ajg.0000000000002405","article-title":"The rising costs of alcohol-associated liver disease in the United States","volume":"119","author":"Julien","year":"2024","journal-title":"Am. J. Gastroenterol."},{"issue":"8","key":"10.1016\/j.nbd.2026.107367_bb0255","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1176\/appi.ajp.162.8.1403","article-title":"The neural basis of addiction: a pathology of motivation and choice","volume":"162","author":"Kalivas","year":"2005","journal-title":"Am. J. Psychiatry"},{"issue":"9","key":"10.1016\/j.nbd.2026.107367_bb0260","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1016\/j.celrep.2018.02.016","article-title":"Action selection and flexible switching controlled by the Intralaminar thalamic neurons","volume":"22","author":"Kato","year":"2018","journal-title":"Cell Rep."},{"issue":"9","key":"10.1016\/j.nbd.2026.107367_bb0265","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.35205","article-title":"A digital cognitive behavioral therapy program for adults with alcohol use disorder: a randomized clinical trial","volume":"7","author":"Kiluk","year":"2024","journal-title":"JAMA Netw. Open"},{"issue":"12","key":"10.1016\/j.nbd.2026.107367_bb0270","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.biopsych.2013.06.024","article-title":"Centromedian-parafascicular deep brain stimulation induces differential functional inhibition of the motor, associative, and limbic circuits in large animals","volume":"74","author":"Kim","year":"2013","journal-title":"Biol. Psychiatry"},{"issue":"6256","key":"10.1016\/j.nbd.2026.107367_bb0275","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1126\/science.aac4690","article-title":"Aldehyde dehydrogenase 1a1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons","volume":"350","author":"Kim","year":"2015","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.nbd.2026.107367_bb0280","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/S2215-0366(16)00104-8","article-title":"Neurobiology of addiction: a neurocircuitry analysis","volume":"3","author":"Koob","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"8","key":"10.1016\/j.nbd.2026.107367_bb0285","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1001\/jama.2018.11406","article-title":"Diagnosis and pharmacotherapy of alcohol use disorder: a review","volume":"320","author":"Kranzler","year":"2018","journal-title":"Jama"},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0290","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1111\/j.1369-1600.2011.00337.x","article-title":"Successful deep brain stimulation of the nucleus accumbens in severe alcohol dependence is associated with changed performance monitoring","volume":"16","author":"Kuhn","year":"2011","journal-title":"Addict. Biol."},{"issue":"2","key":"10.1016\/j.nbd.2026.107367_bb0295","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.neuron.2016.06.010","article-title":"Activation of direct and indirect pathway medium spiny neurons drives distinct brain-wide responses","volume":"91","author":"Lee","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2026.107367_bb0300","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3389\/fnsys.2019.00028","article-title":"Dorsal striatal circuits for habits, compulsions and addictions","volume":"13","author":"Lipton","year":"2019","journal-title":"Front. Syst. Neurosci."},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0305","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1038\/npp.2013.350","article-title":"Deleterious effects of a low amount of ethanol on LTP-like plasticity in human cortex","volume":"39","author":"L\u00fccke","year":"2014","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0310","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s11065-018-9393-5","article-title":"Efficacy of invasive and non-invasive brain modulation interventions for addiction","volume":"29","author":"Luigjes","year":"2019","journal-title":"Neuropsychol. Rev."},{"issue":"3","key":"10.1016\/j.nbd.2026.107367_bb0315","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/s41593-018-0081-9","article-title":"Bidirectional and long-lasting control of alcohol-seeking behavior by corticostriatal LTP and LTD","volume":"21","author":"Ma","year":"2018","journal-title":"Nat. Neurosci."},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0320","doi-asserted-by":"crossref","DOI":"10.1172\/JCI154969","article-title":"Chronic alcohol drinking persistently suppresses thalamostriatal excitation of cholinergic neurons to impair cognitive flexibility","volume":"132","author":"Ma","year":"2022","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.nbd.2026.107367_bb0325","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2147\/SAR.S362864","article-title":"Efficacy of cognitive behavioral therapy for alcohol and other drug use disorders: is a one-size-fits-all approach appropriate?","volume":"14","author":"Magill","year":"2023","journal-title":"Subst. Abus. Rehabil."},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0330","doi-asserted-by":"crossref","first-page":"fcac290","DOI":"10.1093\/braincomms\/fcac290","article-title":"Intrinsic brain functional connectivity patterns in alcohol use disorder","volume":"4","author":"Maleki","year":"2022","journal-title":"Brain Commun."},{"key":"10.1016\/j.nbd.2026.107367_bb0335","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.cobeha.2017.11.005","article-title":"Regulation of habit formation in the dorsal striatum","volume":"20","author":"Malvaez","year":"2018","journal-title":"Curr. Opin. Behav. Sci."},{"issue":"3","key":"10.1016\/j.nbd.2026.107367_bb0340","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2019.02.035","article-title":"Distinct cortical-thalamic-striatal circuits through the Parafascicular nucleus","volume":"102","author":"Mandelbaum","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2026.107367_bb0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2022.105878","article-title":"Connectivity of the corticostriatal and thalamostriatal systems in normal and parkinsonian states: an update","volume":"174","author":"Martel","year":"2022","journal-title":"Neurobiol. Dis."},{"issue":"2","key":"10.1016\/j.nbd.2026.107367_bb0350","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1152\/jn.2001.85.2.960","article-title":"Neurons in the thalamic CM-pf complex supply striatal neurons with information about behaviorally significant sensory events","volume":"85","author":"Matsumoto","year":"2001","journal-title":"J. Neurophysiol."},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0355","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.neuron.2019.03.004","article-title":"Circuit mechanisms of Parkinson\u2019s disease","volume":"101","author":"McGregor","year":"2019","journal-title":"Neuron"},{"issue":"17","key":"10.1016\/j.nbd.2026.107367_bb0360","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1001\/jama.2023.19761","article-title":"Pharmacotherapy for alcohol use disorder: a systematic review and Meta-analysis","volume":"330","author":"McPheeters","year":"2023","journal-title":"Jama"},{"issue":"5","key":"10.1016\/j.nbd.2026.107367_bb0365","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.celrep.2017.04.024","article-title":"Distinct Corticostriatal GABAergic neurons modulate striatal output neurons and motor activity","volume":"19","author":"Melzer","year":"2017","journal-title":"Cell Rep."},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0370","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/j.brs.2024.07.014","article-title":"Temporal interference electrical neurostimulation at 20 Hz beat frequency leads to increased fMRI BOLD activation in orbitofrontal cortex in humans","volume":"17","author":"Modak","year":"2024","journal-title":"Brain Stimul."},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0375","doi-asserted-by":"crossref","first-page":"21040","DOI":"10.1038\/s41598-024-71841-1","article-title":"Non-invasive temporal interference brain stimulation reduces preference on morphine-induced conditioned place preference in rats","volume":"14","author":"Mojiri","year":"2024","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0380","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1055\/s-0042-104507","article-title":"Nucleus Accumbens deep brain stimulation for alcohol addiction - safety and clinical long-term results of a pilot trial","volume":"49","author":"M\u00fcller","year":"2016","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.nbd.2026.107367_bb0385","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpsychires.2020.04.003","article-title":"Predicting relapse after alcohol use disorder treatment in a high-risk cohort: the roles of anhedonia and smoking","volume":"126","author":"Nguyen","year":"2020","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.nbd.2026.107367_bb0390","doi-asserted-by":"crossref","first-page":"3778","DOI":"10.1038\/ncomms4778","article-title":"Enhanced flexibility of place discrimination learning by targeting striatal cholinergic interneurons","volume":"5","author":"Okada","year":"2014","journal-title":"Nat. Commun."},{"issue":"14","key":"10.1016\/j.nbd.2026.107367_bb0395","doi-asserted-by":"crossref","first-page":"3729","DOI":"10.1523\/JNEUROSCI.5731-07.2008","article-title":"Brain chromatin remodeling: a novel mechanism of alcoholism","volume":"28","author":"Pandey","year":"2008","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.nbd.2026.107367_bb0400","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.neuron.2023.11.024","article-title":"Restoration of a paraventricular thalamo-accumbal behavioral suppression circuit prevents reinstatement of heroin seeking","volume":"112","author":"Paniccia","year":"2024","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2026.107367_bb0405","series-title":"Receipt of Services for Substance Use and Mental Health Issues Among Adults: Results From the 2016 National Survey on Drug Use and Health","first-page":"1","author":"Park-Lee","year":"2012"},{"key":"10.1016\/j.nbd.2026.107367_bb0410","doi-asserted-by":"crossref","DOI":"10.1016\/j.jns.2020.116718","article-title":"Treatment resistant opioid use disorder (TROUD): definition, rationale, and recommendations","volume":"411","author":"Patterson Silver Wolf","year":"2020","journal-title":"J. Neurol. Sci."},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0415","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/nrn3746","article-title":"Obsessive-compulsive disorder: an integrative genetic and neurobiological perspective","volume":"15","author":"Pauls","year":"2014","journal-title":"Nat. Rev. Neurosci."},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0420","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.parkreldis.2007.11.005","article-title":"Deep brain stimulation of CM\/PF of thalamus could be the new elective target for tremor in advanced Parkinson\u2019s disease?","volume":"14","author":"Peppe","year":"2008","journal-title":"Parkinsonism Relat. Disord."},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0425","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1111\/add.13757","article-title":"The relationship between different dimensions of alcohol use and the burden of disease-an update","volume":"112","author":"Rehm","year":"2017","journal-title":"Addiction"},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0430","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41467-017-02615-9","article-title":"Chronic alcohol exposure disrupts top-down control over basal ganglia action selection to produce habits","volume":"9","author":"Renteria","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.nbd.2026.107367_bb0435","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.67065","article-title":"Mechanism for differential recruitment of orbitostriatal transmission during actions and outcomes following chronic alcohol exposure","volume":"10","author":"Renteria","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.nbd.2026.107367_bb0440","doi-asserted-by":"crossref","first-page":"1242929","DOI":"10.3389\/fnsys.2023.1242929","article-title":"Basal ganglia for beginners: the basic concepts you need to know and their role in movement control","volume":"17","author":"Rocha","year":"2023","journal-title":"Front. Syst. Neurosci."},{"issue":"5","key":"10.1016\/j.nbd.2026.107367_bb0445","doi-asserted-by":"crossref","first-page":"e73","DOI":"10.1016\/j.amepre.2015.05.031","article-title":"2010 national and state costs of excessive alcohol consumption","volume":"49","author":"Sacks","year":"2015","journal-title":"Am. J. Prev. Med."},{"issue":"2\u20133","key":"10.1016\/j.nbd.2026.107367_bb0450","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.brainresbull.2008.09.016","article-title":"The primate centromedian-parafascicular complex: anatomical organization with a note on neuromodulation","volume":"78","author":"Sadikot","year":"2009","journal-title":"Brain Res. Bull."},{"issue":"3","key":"10.1016\/j.nbd.2026.107367_bb0455","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0193-953X(05)70181-7","article-title":"Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder","volume":"23","author":"Saxena","year":"2000","journal-title":"Psychiatr. Clin. North Am."},{"key":"10.1016\/j.nbd.2026.107367_bb0460","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/bs.irn.2017.05.024","article-title":"Depression and anxiety in Parkinson\u2019s disease","volume":"133","author":"Schrag","year":"2017","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.nbd.2026.107367_bb0465","doi-asserted-by":"crossref","DOI":"10.1016\/j.addicn.2022.100056","article-title":"Circuit dysfunctions of associative and sensorimotor basal ganglia loops in alcohol use disorder: insights from animal models","volume":"5","author":"Sitzia","year":"2023","journal-title":"Addict. Neurosci."},{"issue":"26","key":"10.1016\/j.nbd.2026.107367_bb0470","doi-asserted-by":"crossref","first-page":"eadm6951","DOI":"10.1126\/sciadv.adm6951","article-title":"Chronic alcohol induces subcircuit-specific striatonigral plasticity enhancing the sensorimotor basal ganglia role in action execution","volume":"10","author":"Sitzia","year":"2024","journal-title":"Sci. Adv."},{"issue":"45","key":"10.1016\/j.nbd.2026.107367_bb0475","doi-asserted-by":"crossref","first-page":"16102","DOI":"10.1523\/JNEUROSCI.4634-11.2011","article-title":"Thalamic contributions to basal ganglia-related behavioral switching and reinforcement","volume":"31","author":"Smith","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nbd.2026.107367_bb0480","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3389\/fnsys.2014.00005","article-title":"The thalamostriatal system in normal and diseased states","volume":"8","author":"Smith","year":"2014","journal-title":"Front. Syst. Neurosci."},{"issue":"3","key":"10.1016\/j.nbd.2026.107367_bb0485","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/mp.2014.38","article-title":"Ethanol-induced epigenetic regulations at the Bdnf gene in C57BL\/6J mice","volume":"20","author":"Stragier","year":"2015","journal-title":"Mol. Psychiatry"},{"issue":"6","key":"10.1016\/j.nbd.2026.107367_bb0490","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1002\/mds.29030","article-title":"Pathway-specific remodeling of Thalamostriatal synapses in a mouse model of Parkinson\u2019s disease","volume":"37","author":"Tanimura","year":"2022","journal-title":"Mov. Disord."},{"issue":"3","key":"10.1016\/j.nbd.2026.107367_bb0495","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/s41583-021-00428-w","article-title":"Cognitive and behavioural flexibility: neural mechanisms and clinical considerations","volume":"22","author":"Uddin","year":"2021","journal-title":"Nat. Rev. Neurosci."},{"issue":"2","key":"10.1016\/j.nbd.2026.107367_bb0500","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/ad2d32","article-title":"Safety, tolerability and blinding efficiency of non-invasive deep transcranial temporal interference stimulation: first experience from more than 250 sessions","volume":"21","author":"Vassiliadis","year":"2024","journal-title":"J. Neural Eng."},{"issue":"36","key":"10.1016\/j.nbd.2026.107367_bb0505","doi-asserted-by":"crossref","first-page":"14446","DOI":"10.1523\/JNEUROSCI.4804-12.2013","article-title":"Deep brain stimulation of the nucleus accumbens shell attenuates cocaine reinstatement through local and antidromic activation","volume":"33","author":"Vassoler","year":"2013","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.nbd.2026.107367_bb0510","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1007\/s00213-024-06532-w","article-title":"Subthalamic high-frequency deep brain stimulation reduces addiction-like alcohol use and the possible negative influence of a peer presence","volume":"242","author":"Vignal","year":"2025","journal-title":"Psychopharmacology"},{"issue":"11","key":"10.1016\/j.nbd.2026.107367_bb0515","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1038\/s41593-023-01456-8","article-title":"Non-invasive temporal interference electrical stimulation of the human hippocampus","volume":"26","author":"Violante","year":"2023","journal-title":"Nat. Neurosci."},{"issue":"3\u20134","key":"10.1016\/j.nbd.2026.107367_bb0520","first-page":"S28.e21-31","article-title":"Deep brain stimulation surgery for alcohol addiction","volume":"80","author":"Voges","year":"2013","journal-title":"World Neurosurg."},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0525","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1056\/NEJMra1511480","article-title":"Neurobiologic advances from the brain disease model of addiction","volume":"374","author":"Volkow","year":"2016","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0530","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1152\/physrev.00014.2018","article-title":"The neuroscience of drug reward and addiction","volume":"99","author":"Volkow","year":"2019","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.nbd.2026.107367_bb0535","doi-asserted-by":"crossref","first-page":"1146492","DOI":"10.3389\/fpsyt.2023.1146492","article-title":"A single case report of STN-DBS for severe crack-cocaine dependence: double-blind ON vs. SHAM randomized controlled assessment","volume":"14","author":"Vorspan","year":"2023","journal-title":"Front. Psychiatry"},{"issue":"2","key":"10.1016\/j.nbd.2026.107367_bb0540","doi-asserted-by":"crossref","first-page":"E11","DOI":"10.3171\/2018.5.FOCUS18163","article-title":"Deep brain stimulation for the treatment of drug addiction","volume":"45","author":"Wang","year":"2018","journal-title":"Neurosurg. Focus"},{"issue":"2","key":"10.1016\/j.nbd.2026.107367_bb0545","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2013.4","article-title":"Chromatin remodeling--a novel strategy to control excessive alcohol drinking","volume":"3","author":"Warnault","year":"2013","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.nbd.2026.107367_bb0550","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2021.769275","article-title":"Target-specific effects of deep brain stimulation for Tourette syndrome: a systematic review and meta-analysis","volume":"12","author":"Wehmeyer","year":"2021","journal-title":"Front. Neurol."},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0555","doi-asserted-by":"crossref","first-page":"997","DOI":"10.3171\/2013.12.JNS13205","article-title":"Reduced ethanol consumption by alcohol-preferring (P) rats following pharmacological silencing and deep brain stimulation of the nucleus accumbens shell","volume":"120","author":"Wilden","year":"2014","journal-title":"J. Neurosurg."},{"issue":"1","key":"10.1016\/j.nbd.2026.107367_bb0560","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12992-025-01124-5","article-title":"Trends and cross-country inequalities of alcohol use disorders: findings from the global burden of disease study 2021","volume":"21","author":"Xie","year":"2025","journal-title":"Glob. Health"},{"issue":"5","key":"10.1016\/j.nbd.2026.107367_bb0565","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines10051192","article-title":"Alcohol use disorder: neurobiology and therapeutics","volume":"10","author":"Yang","year":"2022","journal-title":"Biomedicines"},{"issue":"4","key":"10.1016\/j.nbd.2026.107367_bb0570","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1007\/s13311-022-01229-4","article-title":"Deep brain stimulation for addictive disorders-where are we now?","volume":"19","author":"Yuen","year":"2022","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.nbd.2026.107367_bb0575","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.neubiorev.2021.06.031","article-title":"Neurobiological correlates of cue-reactivity in alcohol-use disorders: a voxel-wise meta-analysis of fMRI studies","volume":"128","author":"Zeng","year":"2021","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"5","key":"10.1016\/j.nbd.2026.107367_bb0580","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.neuron.2018.04.027","article-title":"Pauses in cholinergic interneuron activity are driven by excitatory input and delayed rectification, with dopamine modulation","volume":"98","author":"Zhang","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.nbd.2026.107367_bb0585","article-title":"High-frequency deep brain stimulation of the substantia Nigra pars Reticulata facilitates extinction and prevents reinstatement of methamphetamine-induced conditioned place preference","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"7918","key":"10.1016\/j.nbd.2026.107367_bb0590","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/s41586-022-04806-x","article-title":"Targeting thalamic circuits rescues motor and mood deficits in PD mice","volume":"607","author":"Zhang","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.nbd.2026.107367_bb0595","doi-asserted-by":"crossref","DOI":"10.1016\/j.pbb.2024.173726","article-title":"Paraventricular thalamus to nucleus accumbens circuit activation decreases long-term relapse of alcohol-seeking behaviour in male mice","volume":"237","author":"Zhao","year":"2024","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.nbd.2026.107367_bb0600","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.32510","article-title":"Pauses in cholinergic interneuron firing exert an inhibitory control on striatal output in vivo","volume":"7","author":"Zucca","year":"2018","journal-title":"Elife"}],"container-title":["Neurobiology of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996126001129?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969996126001129?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T11:26:39Z","timestamp":1785151599000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969996126001129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":118,"alternative-id":["S0969996126001129"],"URL":"https:\/\/doi.org\/10.1016\/j.nbd.2026.107367","relation":{},"ISSN":["0969-9961"],"issn-type":[{"value":"0969-9961","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thalamostriatal circuit as a therapeutic target of alcohol use disorder","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbd.2026.107367","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"107367"}}