{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:16:08Z","timestamp":1761822968978},"reference-count":57,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2006,11,1]],"date-time":"2006-11-01T00:00:00Z","timestamp":1162339200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurologic Clinics"],"published-print":{"date-parts":[[2006,11]]},"DOI":"10.1016\/j.ncl.2006.05.003","type":"journal-article","created":{"date-parts":[[2007,1,10]],"date-time":"2007-01-10T15:06:46Z","timestamp":1168441606000},"page":"681-695","source":"Crossref","is-referenced-by-count":8,"title":["Carotid Artery Stenting Versus Carotid Endarterectomy: Current Status"],"prefix":"10.1016","volume":"24","author":[{"given":"Kevin M.","family":"Barrett","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas G.","family":"Brott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ncl.2006.05.003_bib1","series-title":"Heart disease and stroke statistics\u20142005 update","author":"American Heart Association","year":"2005"},{"key":"10.1016\/j.ncl.2006.05.003_bib2","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1002\/ana.410250410","article-title":"Infarcts of undetermined cause: the NINCDS Stroke Data Bank","volume":"25","author":"Sacco","year":"1989","journal-title":"Ann Neurol"},{"key":"10.1016\/j.ncl.2006.05.003_bib3","doi-asserted-by":"crossref","first-page":"3289","DOI":"10.1001\/jama.266.23.3289","article-title":"Carotid endarterectomy and prevention of cerebral ischemia in symptomatic carotid stenosis","volume":"266","author":"Mayberg","year":"1991","journal-title":"JAMA"},{"key":"10.1016\/j.ncl.2006.05.003_bib4","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S0140-6736(97)09292-1","article-title":"Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST)","volume":"351","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.ncl.2006.05.003_bib5","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1056\/NEJM199811123392002","article-title":"Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis","volume":"339","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ncl.2006.05.003_bib6","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1001\/jama.1995.03520420037035","article-title":"Endarterectomy for asymptomatic carotid artery stenosis","volume":"273","author":"Executive Committee for the Asymptomatic Carotid Atherosclerosis Study","year":"1995","journal-title":"JAMA"},{"key":"10.1016\/j.ncl.2006.05.003_bib7","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/S0140-6736(04)16146-1","article-title":"MRC Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group. Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomized controlled trial","volume":"363","author":"Halliday","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.ncl.2006.05.003_bib8","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1056\/NEJM199108153250701","article-title":"Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis","volume":"325","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ncl.2006.05.003_bib9","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/0140-6736(91)92916-P","article-title":"Interim results for symptomatic patients with severe (70\u201399%) or with mild (0\u201329%) carotid stenosis: European Carotid Surgery Trialists' Collaborative Group","volume":"337","author":"MRC European Carotid Surgery Trial","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.ncl.2006.05.003_bib10","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1161\/01.STR.0000199147.30016.74","volume":"37","author":"Sacco","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.ncl.2006.05.003_bib11","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1161\/01.STR.29.2.554","article-title":"Guidelines for carotid endarterectomy: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association","volume":"29","author":"Biller","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.ncl.2006.05.003_bib12","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001923.pub2","article-title":"Carotid endarterectomy for asymptomatic carotid stenosis","volume":"4","author":"Chambers","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ncl.2006.05.003_bib13","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(96)09457-3","article-title":"A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)","volume":"348","author":"CAPRIE Steering Committeee","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.ncl.2006.05.003_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-510X(96)00308-5","article-title":"European Stroke Prevention Study 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke","volume":"143","author":"Diener","year":"1996","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.ncl.2006.05.003_bib15","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S0140-6736(04)15690-0","article-title":"Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions","volume":"363","author":"Collins","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.ncl.2006.05.003_bib16","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1001\/jama.289.19.2560","article-title":"National High Blood Pressure Education Program Coordinating Committeee. The Seventh Report of the Joint National Committeee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 Report","volume":"289","author":"Chobanian","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.ncl.2006.05.003_bib17","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.ejvs.2004.07.022","article-title":"Does the modern concept of \u2018Best Medical Therapy\u2019 render carotid surgery obsolete?","volume":"28","author":"Naylor","year":"2004","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib18","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S1042-3680(18)30145-1","article-title":"Cervical carotid revascularization","volume":"11","author":"Guterman","year":"2000","journal-title":"Neurosurg Clin N Am"},{"key":"10.1016\/j.ncl.2006.05.003_bib19","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1583\/1545-1550(2003)010<0851:HABAEC>2.0.CO;2","article-title":"Hypotension and bradycardia after elective carotid stenting: frequency and risk factors","volume":"10","author":"Mlekusch","year":"2003","journal-title":"J Endovasc Ther"},{"key":"10.1016\/j.ncl.2006.05.003_bib20","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1148\/radiology.215.3.r00jn04677","article-title":"Postprocedural hypotension after carotid artery stent placement: predictors and short- and long-term clinical outcomes","volume":"215","author":"Dangas","year":"2000","journal-title":"Radiology"},{"key":"10.1016\/j.ncl.2006.05.003_bib21","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1161\/01.STR.30.10.2086","article-title":"Frequency and determinants of postprocedural hemodynamic instability after carotid angioplasty and stenting","volume":"30","author":"Qureshi","year":"1999","journal-title":"Stroke"},{"key":"10.1016\/j.ncl.2006.05.003_bib22","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/S0002-9149(98)00562-1","article-title":"Acute hemodynamic changes during carotid artery stenting","volume":"82","author":"Mendelsohn","year":"1998","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ncl.2006.05.003_bib23","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1001\/archneur.58.9.1410","article-title":"Characteristics of cerebral microembolism during carotid stenting and angioplasty alone","volume":"58","author":"Orlandi","year":"2001","journal-title":"Arch Neurol"},{"key":"10.1016\/j.ncl.2006.05.003_bib24","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1161\/01.STR.28.12.2460","article-title":"Comparison of hemodynamic cerebral ischemia and microembolic signals detected during carotid endarterectomy and carotid angioplasty","volume":"28","author":"Crawley","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.ncl.2006.05.003_bib25","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/ccd.10232","article-title":"Retinal embolization during carotid angioplasty and stenting: mechanisms and role for cerebral protection systems","volume":"56","author":"Wilentz","year":"2002","journal-title":"Cathet Cardiovasc Interv"},{"key":"10.1016\/j.ncl.2006.05.003_bib26","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1148\/radiol.2242011302","article-title":"New brain lesions at MR imaging after carotid angioplasty and stent placement","volume":"224","author":"van Heesewijk","year":"2002","journal-title":"Radiology"},{"key":"10.1016\/j.ncl.2006.05.003_bib27","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1583\/03-1128.1","article-title":"Cerebral ischemia after carotid intervention","volume":"11","author":"Flach","year":"2004","journal-title":"J\u00a0Endovasc Ther"},{"key":"10.1016\/j.ncl.2006.05.003_bib28","first-page":"2336","article-title":"MR and clinical follow-up of diffusion-weighted cerebral lesions after carotid artery stenting","volume":"26","author":"Hauth","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.ncl.2006.05.003_bib29","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.3171\/foc.2005.18.1.4","article-title":"Toward clinical equipoise: the current case for carotid angioplasty and stent placement","volume":"18","author":"Levy","year":"2005","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.ncl.2006.05.003_bib30","first-page":"103","article-title":"Carotid stenting with filter protection: correlation of ACT values with angiographic and histopathologic findings","volume":"30","author":"Castellan","year":"2003","journal-title":"J Neuroradiol"},{"key":"10.1016\/j.ncl.2006.05.003_bib31","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1583\/05-1615R.1","article-title":"Procedure-related complications and early neurological adverse events of unprotected and protected carotid stenting: temporal trends in a consecutive patient series","volume":"12","author":"Boltuch","year":"2005","journal-title":"J Endovasc Ther"},{"key":"10.1016\/j.ncl.2006.05.003_bib32","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.amjmed.2003.09.043","article-title":"Routine use of cerebral protection during carotid artery stenting: results of a multicenter registry of 753 patients","volume":"116","author":"Reimers","year":"2004","journal-title":"Am J Med"},{"key":"10.1016\/j.ncl.2006.05.003_bib33","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1583\/1545-1550(2002)009<0777:NOACSP>2.0.CO;2","article-title":"Neurological outcomes after carotid stenting protected with the NeuroShield filter compared to unprotected stenting","volume":"9","author":"Macdonald","year":"2002","journal-title":"J Endovasc Ther"},{"key":"10.1016\/j.ncl.2006.05.003_bib34","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/S0741-5214(98)70182-X","article-title":"Randomized study of carotid angioplasty and stenting versus carotid endarterectomy: a stopped trial","volume":"28","author":"Naylor","year":"1998","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib35","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1161\/str.32.suppl_1.325-d","article-title":"Results of a multicenter prospective randomized trial of carotid artery stenting vs. carotid endarterectomy","volume":"32","author":"Alberts","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.ncl.2006.05.003_bib36","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1016\/S0140-6736(00)04893-5","article-title":"Endovascular versus surgical treatment in patients with carotid stenosis in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): a randomised trial","volume":"357","author":"Investigators CAVATAS","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.ncl.2006.05.003_bib37","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1016\/S0735-1097(01)01595-9","article-title":"Carotid angioplasty and stenting versus carotid endarterectomy: randomized trial in a community hospital","volume":"38","author":"Brooks","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ncl.2006.05.003_bib38","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1056\/NEJMoa040127","article-title":"Protected carotid-artery stenting versus endarterectomy in high-risk patients","volume":"351","author":"Yadav","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ncl.2006.05.003_bib39","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1161\/01.STR.0000158921.51037.64","article-title":"Safety and efficacy of endovascular treatment of carotid artery stenosis compared with carotid endarterectomy: a Cochrane systematic review of the randomized evidence","volume":"36","author":"Coward","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.ncl.2006.05.003_bib40","first-page":"139","article-title":"CREST (Carotid Revascularization Endarterectomy versus Stent Trial): background, design, and current status","volume":"13","author":"Hobson","year":"2000","journal-title":"Semin Vasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib41","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.jvs.2004.08.039","article-title":"Credentialing of surgeons as interventionalists for carotid artery stenting: experience from the lead-in phase of CREST","volume":"40","author":"Hobson","year":"2004","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib42","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.jvs.2004.10.022","article-title":"Carotid artery stenting is associated with increased complications in octogenarians: 30-day stroke and death rates in the CREST lead-in phase","volume":"40","author":"Hobson","year":"2004","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib43","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1007\/s10016-005-7977-z","article-title":"Carotid artery stenting in octogenarians: Is it too risky?","volume":"19","author":"Longo","year":"2005","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib44","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1161\/01.STR.0000165919.26944.05","article-title":"Carotid artery stenting: meeting the recruitment of a clinical trial","volume":"36","author":"Hobson","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.ncl.2006.05.003_bib45","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1159\/000078753","article-title":"International Carotid Stenting Study: protocol for a randomized clinical trial comparing carotid stenting with endarterectomy in symptomatic carotid artery stenosis","volume":"18","author":"Featherstone","year":"2004","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.ncl.2006.05.003_bib46","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1159\/000078751","article-title":"Endarterectomy vs. angioplasty in patients with symptomatic severe carotid stenosis (EVA-3S) trial","volume":"18","author":"Mas","year":"2004","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.ncl.2006.05.003_bib47","first-page":"18","article-title":"Carotid angioplasty and stenting with and without cerebral protection: Clinical alert from the endarterectomy versus angioplasty in patients with symptomatic severe carotid stenosis (EVA-3S) trial","volume":"35","author":"EVA-3S Investigators","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.ncl.2006.05.003_bib48","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1159\/000078752","article-title":"The Stent-supported Percutaneous Angioplasty of the Carotid Artery Vs. Endarterectomy Trial","volume":"18","author":"Ringleb","year":"2004","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.ncl.2006.05.003_bib49","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000078750","article-title":"Carotid artery stenting: the need for randomized trials","volume":"18","author":"Brown","year":"2004","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.ncl.2006.05.003_bib50","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1016\/S0735-1097(01)01595-9","article-title":"Carotid angioplasty and stenting versus carotid endarterectomy: randomized trial in a community hospital","volume":"38","author":"Brooks","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ncl.2006.05.003_bib51","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0741-5214(98)70287-3","article-title":"A cost comparison of balloon angioplasty and stenting versus endarterectomy for the treatment of carotid artery stenosis","volume":"27","author":"Jordan","year":"1998","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib52","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1067\/mva.2003.124","article-title":"Is carotid angioplasty and stenting more cost effective than carotid endarterectomy?","volume":"37","author":"Kilaru","year":"2003","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib53","doi-asserted-by":"crossref","first-page":"904","DOI":"10.3171\/jns.2004.101.6.0904","article-title":"Cost of treating high-risk symptomatic carotid artery stenosis: stent insertion and angioplasty compared with endarterectomy","volume":"101","author":"Ecker","year":"2004","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ncl.2006.05.003_bib54","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1067\/mva.2001.111880","article-title":"In-stent restenosis after carotid angioplasty-stenting: incidence and management","volume":"33","author":"Chakhtoura","year":"2001","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib55","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1097\/00001573-200211000-00014","article-title":"Carotid artery stenting: acute and long-term results","volume":"17","author":"Shawl","year":"2002","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.ncl.2006.05.003_bib56","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1053\/ejvs.2002.1974","article-title":"Restenosis after carotid angioplasty and stenting: a follow-up study with duplex ultrasonography","volume":"26","author":"Christiaans","year":"2003","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.ncl.2006.05.003_bib57","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.4065\/79.9.1197","article-title":"Carotid revascularization for prevention of stroke: Carotid endarterectomy and carotid artery stenting","volume":"79","author":"Brott","year":"2004","journal-title":"Mayo Clin Proc"}],"container-title":["Neurologic Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733861906000569?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733861906000569?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T01:05:52Z","timestamp":1707527152000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0733861906000569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11]]},"references-count":57,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["S0733861906000569"],"URL":"https:\/\/doi.org\/10.1016\/j.ncl.2006.05.003","relation":{},"ISSN":["0733-8619"],"issn-type":[{"value":"0733-8619","type":"print"}],"subject":[],"published":{"date-parts":[[2006,11]]}}}