{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T15:50:58Z","timestamp":1713196258280},"reference-count":125,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","neurologic.theclinics.com","clinicalkey.es","theclinics.com","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurologic Clinics"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.ncl.2016.04.002","type":"journal-article","created":{"date-parts":[[2016,7,19]],"date-time":"2016-07-19T16:30:24Z","timestamp":1468945824000},"page":"525-545","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Syncope: Case Studies"],"prefix":"10.1016","volume":"34","author":[{"given":"Inna","family":"Kleyman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis H.","family":"Weimer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"21","key":"10.1016\/j.ncl.2016.04.002_bib1","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1093\/eurheartj\/ehp298","article-title":"Guidelines for the diagnosis and management of syncope (version 2009)","volume":"30","author":"Task Force for the Diagnosis and Management of Syncope","year":"2009","journal-title":"Eur Heart J"},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib2","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0031-3955(05)70113-9","article-title":"Syncope in the pediatric patient: the cardiologist's perspective","volume":"46","author":"Lewis","year":"1999","journal-title":"Pediatr Clin North Am"},{"issue":"16","key":"10.1016\/j.ncl.2016.04.002_bib3","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1093\/eurheartj\/ehl147","article-title":"Vasovagal syncope in medical students and their first-degree relatives","volume":"27","author":"Serletis","year":"2006","journal-title":"Eur Heart J"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib4","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.eupc.2003.09.003","article-title":"Clinical spectrum of neurally mediated reflex syncopes","volume":"6","author":"Alboni","year":"2004","journal-title":"Europace"},{"issue":"10","key":"10.1016\/j.ncl.2016.04.002_bib5","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/j.amjcard.2005.07.047","article-title":"Relation of clinical presentation of syncope to the age of patients","volume":"96","author":"Del Rosso","year":"2005","journal-title":"Am J Cardiol"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib6","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1540-8167.2005.00267.x","article-title":"Age of first faint in patients with vasovagal syncope","volume":"17","author":"Sheldon","year":"2006","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"issue":"23","key":"10.1016\/j.ncl.2016.04.002_bib7","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1161\/01.CIR.102.23.2898","article-title":"The elusive pathophysiology of neurally mediated syncope","volume":"102","author":"Mosqueda-Garcia","year":"2000","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib8","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ccl.2012.10.010","article-title":"Vasovagal syncope: new physiologic insights","volume":"31","author":"Jardine","year":"2013","journal-title":"Cardiol Clin"},{"key":"10.1016\/j.ncl.2016.04.002_bib9","series-title":"Vasovagal syncope","first-page":"53","author":"Alboni","year":"2015"},{"issue":"5","key":"10.1016\/j.ncl.2016.04.002_bib10","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1161\/01.CIR.0000023924.66889.4C","article-title":"Role of endogenous adenosine as a modulator of syncope induced during tilt testing","volume":"106","author":"Saadjian","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.ncl.2016.04.002_bib11","doi-asserted-by":"crossref","first-page":"e6784","DOI":"10.1371\/journal.pone.0006784","article-title":"Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in\u00a0vivo","volume":"4","author":"Koeppen","year":"2009","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.ncl.2016.04.002_bib12","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1093\/europace\/euu082","article-title":"The adenosine triphosphate test in the diagnosis of unexplained syncope: a test looking for a home","volume":"16","author":"Matthews","year":"2014","journal-title":"Europace"},{"issue":"7","key":"10.1016\/j.ncl.2016.04.002_bib13","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1093\/qjmed\/hcp048","article-title":"The intravenous adenosine test: a new test for the identification of bradycardia pacing indications? A pilot study in subjects with bradycardia pacing indications, vasovagal syncope and controls","volume":"102","author":"Parry","year":"2009","journal-title":"QJM"},{"issue":"21","key":"10.1016\/j.ncl.2016.04.002_bib14","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1161\/CIRCULATIONAHA.111.082313","article-title":"Pacemaker therapy in patients with neurally mediated syncope and documented asystole third international study on syncope of uncertain etiology (ISSUE-3): a randomized trial","volume":"125","author":"Brignole","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.ncl.2016.04.002_bib15","unstructured":"Parry SW. Adenosine testing to DEtermine the need for Pacing Therapy with the additional use of an Implantable Loop Recorder (ADEPT-ILR study)\u2014the efficacy of permanent pacing in patients presenting to emergency medical services with syncope and a positive intravenous adenosine: a randomised, double-blind, placebo-controlled, cross-over trial. ISRCT62199741."},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib16","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/brain\/awt332","article-title":"The semiology of tilt-induced reflex syncope in relation to electroencephalographic changes","volume":"137","author":"van Dijk","year":"2014","journal-title":"Brain"},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib17","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0002-9343(83)91201-9","article-title":"Differential changes of autonomic nervous system function with age in man","volume":"75","author":"Pfeifer","year":"1983","journal-title":"Am J Med"},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib18","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1210\/edrv-1-2-167","article-title":"Sympathetic nervous system and aging in man","volume":"1","author":"Rowe","year":"1980","journal-title":"Endocr Rev"},{"issue":"23","key":"10.1016\/j.ncl.2016.04.002_bib19","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1212\/WNL.0000000000002184","article-title":"Tilt-induced vasovagal syncope and psychogenic pseudosyncope overlapping clinical entities","volume":"85","author":"Blad","year":"2015","journal-title":"Neurology"},{"issue":"8","key":"10.1016\/j.ncl.2016.04.002_bib20","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1212\/WNL.0b013e3182a1aa88","article-title":"The semiology of tilt-induced psychogenic pseudosyncope","volume":"81","author":"Tannemaat","year":"2013","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib21","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/BF03324968","article-title":"Carotid sinus syndrome is common in very elderly patients undergoing tilt table testing and carotid sinus massage because of syncope or unexplained falls","volume":"23","author":"Paling","year":"2011","journal-title":"Aging Clin Exp Res"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib22","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s40520-013-0124-8","article-title":"Clinical aspects and diagnostic relevance of neuroautonomic evaluation in patients with unexplained falls","volume":"26","author":"Rafanelli","year":"2014","journal-title":"Aging Clin Exp Res"},{"issue":"9","key":"10.1016\/j.ncl.2016.04.002_bib23","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1136\/heartjnl-2014-307096","article-title":"The different clinical presentations of vasovagal syncope","volume":"101","author":"Alboni","year":"2015","journal-title":"Heart"},{"issue":"5","key":"10.1016\/j.ncl.2016.04.002_bib24","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.1136\/hrt.2003.031294","article-title":"Vasovagal syncope interrupting sleep?","volume":"90","author":"Krediet","year":"2004","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib25","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/s10286-006-0314-y","article-title":"Fainting in your sleep?","volume":"16","author":"Jardine","year":"2006","journal-title":"Clin Auton Res"},{"issue":"9","key":"10.1016\/j.ncl.2016.04.002_bib26","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.sleep.2010.04.013","article-title":"Sleep syncope: important clinical associations with phobia and vagotonia","volume":"11","author":"Busweiler","year":"2010","journal-title":"Sleep Med"},{"issue":"16","key":"10.1016\/j.ncl.2016.04.002_bib27","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1212\/WNL.0b013e31828cfad0","article-title":"Autosomal dominant vasovagal syncope clinical features and linkage to chromosome 15q26","volume":"80","author":"Klein","year":"2013","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib28","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1046\/j.1540-8167.2005.40768.x","article-title":"Tilt-table testing in the evaluation of syncope","volume":"16","author":"Benditt","year":"2005","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"issue":"22","key":"10.1016\/j.ncl.2016.04.002_bib29","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1016\/j.ehj.2004.09.004","article-title":"Guidelines on management (diagnosis and treatment) of syncope\u2013update 2004","volume":"25","author":"Brignole","year":"2004","journal-title":"Eur Heart J"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib30","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0002-9343(84)90122-0","article-title":"Carotid sinus hypersensitivity: case report and review of the literature","volume":"77","author":"Coplan","year":"1984","journal-title":"Am J Med"},{"issue":"11","key":"10.1016\/j.ncl.2016.04.002_bib31","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1136\/jnnp.2006.093518","article-title":"Unexplained syncope\u2014is screening for carotid sinus hypersensitivity indicated in all patients aged> 40 years?","volume":"77","author":"Humm","year":"2006","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"issue":"15","key":"10.1016\/j.ncl.2016.04.002_bib32","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/S0002-9149(96)00207-X","article-title":"Observations on carotid sinus hypersensitivity from direct intraneural recordings of sympathetic nerve traffic","volume":"77","author":"Luck","year":"1996","journal-title":"Am J Cardiol"},{"issue":"8","key":"10.1016\/j.ncl.2016.04.002_bib33","first-page":"477","article-title":"A\u00a0study of carotid sinus massage and head-up tilt table testing in patients with syncope and near-syncope","volume":"14","author":"von zur Muhlen","year":"2002","journal-title":"J\u00a0Invasive Cardiol"},{"issue":"11","key":"10.1016\/j.ncl.2016.04.002_bib34","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.1161\/01.CIR.95.11.2548","article-title":"Assessment of a newly recognized association carotid sinus hypersensitivity and denervation of sternocleidomastoid muscles","volume":"95","author":"Blanc","year":"1997","journal-title":"Circulation"},{"issue":"11","key":"10.1016\/j.ncl.2016.04.002_bib35","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1093\/europace\/euq317","article-title":"Carotid sinus hypersensitivity: disease state or clinical sign of ageing? Insights from a controlled study of autonomic function in symptomatic and asymptomatic subjects","volume":"12","author":"Tan","year":"2010","journal-title":"Europace"},{"key":"10.1016\/j.ncl.2016.04.002_bib36","first-page":"78","article-title":"Complications related to carotid sinus massage in 502 ambulatory patients","volume":"92","author":"Lacerda","year":"2009","journal-title":"Arq Bras Cardiol"},{"issue":"10","key":"10.1016\/j.ncl.2016.04.002_bib37","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1093\/europace\/eum180","article-title":"Less syncope and milder symptoms in patients treated with pacing for induced cardioinhibitory carotid sinus syndrome: a randomized study","volume":"9","author":"Claesson","year":"2007","journal-title":"Europace"},{"issue":"5","key":"10.1016\/j.ncl.2016.04.002_bib38","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/hrt.2008.153189","article-title":"Pacing in elderly recurrent fallers with carotid sinus hypersensitivity: a randomised, double-blind, placebo controlled crossover trial","volume":"95","author":"Parry","year":"2009","journal-title":"Heart"},{"issue":"5","key":"10.1016\/j.ncl.2016.04.002_bib39","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1136\/hrt.2009.176206","article-title":"Carotid sinus syndrome, should we pace? A multicentre, randomised control trial (Safepace 2)","volume":"96","author":"Ryan","year":"2010","journal-title":"Heart"},{"issue":"7","key":"10.1016\/j.ncl.2016.04.002_bib40","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1111\/j.1540-8159.1989.tb01982.x","article-title":"Pacing in patients with carotid sinus and vasovagal syndromes","volume":"12","author":"Sutton","year":"1989","journal-title":"Pacing Clin Electrophysiol"},{"issue":"6","key":"10.1016\/j.ncl.2016.04.002_bib41","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1136\/hrt.77.6.553","article-title":"A\u00a0study comparing VVI and DDI pacing in elderly patients with carotid sinus syndrome","volume":"77","author":"McIntosh","year":"1997","journal-title":"Heart"},{"issue":"10","key":"10.1016\/j.ncl.2016.04.002_bib42","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/S0002-9149(99)80207-0","article-title":"A\u00a0positive response to head-up tilt testing predicts syncopal recurrence in carotid sinus syndrome patients with permanent pacemakers","volume":"76","author":"Gaggioli","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ncl.2016.04.002_bib43","doi-asserted-by":"crossref","first-page":"216206","DOI":"10.5402\/2012\/216206","article-title":"Recurrent syncope in patients with carotid sinus hypersensitivity","volume":"2012","author":"Lagi","year":"2012","journal-title":"ISRN Cardiol"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib44","first-page":"189","article-title":"Carotid sinus syndrome: a review of the literature and our experience using carotid sinus denervation","volume":"42","author":"Fachinetti","year":"1998","journal-title":"J\u00a0Neurosurg Sci"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib45","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1532-5415.2005.53021.x","article-title":"Treatment of vasodepressor carotid sinus syndrome with midodrine: a randomized, controlled pilot study","volume":"53","author":"Moore","year":"2005","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib46","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1136\/hrt.69.4.308","article-title":"Benefits of fludrocortisone in the treatment of symptomatic vasodepressor carotid sinus syndrome","volume":"69","author":"Da Costa","year":"1993","journal-title":"Br Heart J"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib47","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1097\/CRD.0000000000000041","article-title":"Carotid sinus syndrome","volume":"23","author":"Amin","year":"2015","journal-title":"Cardiol Rev"},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib48","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1111\/j.1540-8159.1997.tb06211.x","article-title":"Neurally mediated syncopal syndromes: pathophysiological concepts and clinical evaluation","volume":"20","author":"Benditt","year":"1997","journal-title":"Pacing Clin Electrophysiol"},{"issue":"12","key":"10.1016\/j.ncl.2016.04.002_bib49","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1001\/archinte.1986.00360240105018","article-title":"Defecation syncope: a symptom with multiple etiologies","volume":"146","author":"Kapoor","year":"1986","journal-title":"Arch Intern Med"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib50","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1540-8159.2011.03290.x","article-title":"Clinical characteristics of defecation and micturition syncope compared with common vasovagal syncope","volume":"35","author":"Bae","year":"2012","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.ncl.2016.04.002_bib51","series-title":"Swallow syncope. Principles of deglutition","first-page":"445","author":"Gawrieh","year":"2013"},{"issue":"7","key":"10.1016\/j.ncl.2016.04.002_bib52","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1111\/j.1540-8159.2004.00559.x","article-title":"Situational syncope","volume":"27","author":"Livanis","year":"2004","journal-title":"Pacing Clin Electrophysiol"},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib53","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/ana.410360217","article-title":"Syncope: a videometric analysis of 56 episodes of transient cerebral hypoxia","volume":"36","author":"Lempert","year":"1994","journal-title":"Ann Neurol"},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib54","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S1474-4422(06)70350-7","article-title":"Seizure versus syncope","volume":"5","author":"McKeon","year":"2006","journal-title":"Lancet Neurol"},{"issue":"7004","key":"10.1016\/j.ncl.2016.04.002_bib55","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/S0140-6736(57)92147-5","article-title":"Electro-encephalographic study of syncope: its differentiation from epilepsy","volume":"270","author":"Gastaut","year":"1957","journal-title":"Lancet"},{"issue":"9133","key":"10.1016\/j.ncl.2016.04.002_bib56","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/S0140-6736(98)03543-0","article-title":"Epileptology of the first-seizure presentation: a clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients","volume":"352","author":"King","year":"1998","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.ncl.2016.04.002_bib57","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1742-1241.2001.tb11145.x","article-title":"Convulsive syncope in young adults: think of a cardiac cause","volume":"55","author":"Patel","year":"2001","journal-title":"Int J Clin Pract"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib58","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3349\/ymj.2010.51.1.77","article-title":"Seizure-like activities during head-up tilt test-induced syncope","volume":"51","author":"Song","year":"2010","journal-title":"Yonsei Med J"},{"issue":"10","key":"10.1016\/j.ncl.2016.04.002_bib59","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1111\/j.1528-1157.1996.tb00536.x","article-title":"The ictal bradycardia syndrome","volume":"37","author":"Reeves","year":"1996","journal-title":"Epilepsia"},{"issue":"12","key":"10.1016\/j.ncl.2016.04.002_bib60","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1093\/brain\/124.12.2361","article-title":"Ictal bradycardia in partial epileptic seizures","volume":"124","author":"Tinuper","year":"2001","journal-title":"Brain"},{"issue":"6","key":"10.1016\/j.ncl.2016.04.002_bib61","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1212\/WNL.48.6.1712","article-title":"Bradycardia and asystole induced by partial seizures: a case report and literature review","volume":"48","author":"Devinsky","year":"1997","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.ncl.2016.04.002_bib62","doi-asserted-by":"crossref","first-page":"581","DOI":"10.7326\/0003-4819-130-7-199904060-00018","article-title":"Cardiac asystole and bradycardia as a manifestation of left temporal lobe complex partial seizure","volume":"130","author":"Locatelli","year":"1999","journal-title":"Ann Intern Med"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib63","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1161\/CIRCULATIONAHA.108.805887","article-title":"Neurogenic orthostatic hypotension a pathophysiological approach","volume":"119","author":"Goldstein","year":"2009","journal-title":"Circulation"},{"issue":"21","key":"10.1016\/j.ncl.2016.04.002_bib64","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1212\/01.wnl.0000335246.93495.92","article-title":"The arterial baroreflex functional organization and involvement in neurologic disease","volume":"71","author":"Benarroch","year":"2008","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib65","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF01845772","article-title":"The head and neck discomfort of autonomic failure: an unrecognized aetiology of headache","volume":"4","author":"Robertson","year":"1994","journal-title":"Clin Auton Res"},{"issue":"5","key":"10.1016\/j.ncl.2016.04.002_bib66","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s10286-015-0295-9","article-title":"Cerebral blood flow during HUTT in young patients with orthostatic intolerance","volume":"25","author":"Lankford","year":"2015","journal-title":"Clin Auton Res"},{"issue":"7","key":"10.1016\/j.ncl.2016.04.002_bib67","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.amjcard.2006.10.067","article-title":"Usefulness of an abnormal cardiovascular response during low-grade head-up tilt-test for discriminating adolescents with chronic fatigue from healthy controls","volume":"99","author":"Wyller","year":"2007","journal-title":"Am J Cardiol"},{"issue":"20","key":"10.1016\/j.ncl.2016.04.002_bib68","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1001\/archinte.162.20.2369","article-title":"Orthostatic hypotension in acute geriatric ward: is it a consistent finding?","volume":"162","author":"Weiss","year":"2002","journal-title":"Arch Intern Med"},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib69","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/BF02291236","article-title":"Consensus statement on the definition of orthostatic hypotension, pure autonomic failure and multiple system atrophy","volume":"6","author":"Kaufmann","year":"1996","journal-title":"Clin Auton Res"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib70","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/jgs.13324","article-title":"Orthostatic hypotension at different times after standing erect in elderly adults","volume":"63","author":"Campos","year":"2015","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib71","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1212\/01.wnl.0000223828.28215.0b","article-title":"Delayed orthostatic hypotension: a frequent cause of orthostatic intolerance","volume":"67","author":"Gibbons","year":"2006","journal-title":"Neurology"},{"issue":"16","key":"10.1016\/j.ncl.2016.04.002_bib72","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1212\/WNL.0000000000002030","article-title":"Clinical implications of delayed orthostatic hypotension: a 10-year follow-up study","volume":"85","author":"Gibbons","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.ncl.2016.04.002_bib73","series-title":"Joslin's Diabetes Mellitus","article-title":"The peripheral nervous system and diabetes","author":"Freeman","year":"2002"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib74","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1093\/brain\/98.3.341","article-title":"The sympathetic nervous system in diabetic neuropathy","volume":"98","author":"Low","year":"1975","journal-title":"Brain"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib75","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1161\/CIRCULATIONAHA.105.584524","article-title":"Stress testing in patients with diabetes mellitus diagnostic and prognostic value","volume":"113","author":"Albers","year":"2006","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.ncl.2016.04.002_bib76","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1212\/WNL.0b013e3182120147","article-title":"Assessing autonomic dysfunction in early diabetic neuropathy the survey of autonomic symptoms","volume":"76","author":"Zilliox","year":"2011","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.ncl.2016.04.002_bib77","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1002\/dmrr.859","article-title":"Evaluation of peripheral and autonomic neuropathy among patients with newly diagnosed impaired glucose tolerance","volume":"24","author":"Isak","year":"2008","journal-title":"Diabetes Metab Res Rev"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib78","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2337\/dc08-1406","article-title":"Noninvasive evaluation of neural impairment in subjects with impaired glucose tolerance","volume":"32","author":"Putz","year":"2009","journal-title":"Diabetes Care"},{"issue":"6","key":"10.1016\/j.ncl.2016.04.002_bib79","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/j.1464-5491.2011.03278.x","article-title":"Cardiovascular autonomic dysfunction is associated with central obesity in persons with impaired glucose tolerance","volume":"28","author":"Laitinen","year":"2011","journal-title":"Diabet Med"},{"issue":"6","key":"10.1016\/j.ncl.2016.04.002_bib80","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.2337\/dc06-0224","article-title":"Lifestyle intervention for pre-diabetic neuropathy","volume":"29","author":"Smith","year":"2006","journal-title":"Diabetes care"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib81","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s10286-007-0426-z","article-title":"Impaired glucose tolerance is associated with postganglionic sudomotor impairment","volume":"17","author":"Grandinetti","year":"2007","journal-title":"Clin Auton Res"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib82","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1111\/dme.12111","article-title":"Autonomic dysfunction and circadian blood pressure variations in people with impaired glucose tolerance","volume":"30","author":"Putz","year":"2013","journal-title":"Diabetic Med"},{"issue":"10","key":"10.1016\/j.ncl.2016.04.002_bib83","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.2337\/db12-0138","article-title":"Neuroadrenergic dysfunction along the diabetes continuum a comparative study in obese metabolic syndrome subjects","volume":"61","author":"Straznicky","year":"2012","journal-title":"Diabetes"},{"issue":"10","key":"10.1016\/j.ncl.2016.04.002_bib84","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1016\/j.metabol.2008.05.012","article-title":"Increased sympathetic reactivity may predict insulin resistance: an 18-year follow-up study","volume":"57","author":"Flaa","year":"2008","journal-title":"Metabolism"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib85","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1002\/ana.21952","article-title":"Treatment-induced diabetic neuropathy: a reversible painful autonomic neuropathy","volume":"67","author":"Gibbons","year":"2010","journal-title":"Ann Neurol"},{"issue":"11","key":"10.1016\/j.ncl.2016.04.002_bib86","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1212\/WNL.0b013e3181d55f4d","article-title":"Stem cell transplantation in patients with autonomic neuropathy due to primary (AL) amyloidosis","volume":"74","author":"Dingli","year":"2010","journal-title":"Neurology"},{"issue":"5","key":"10.1016\/j.ncl.2016.04.002_bib87","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/ajh.23400","article-title":"Immunoglobulin light chain amyloidosis: 2013 update on diagnosis, prognosis, and treatment","volume":"88","author":"Gertz","year":"2013","journal-title":"Am J Hematol"},{"key":"10.1016\/j.ncl.2016.04.002_bib88","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1750-1172-8-31","article-title":"Guideline of transthyretin-related hereditary amyloidosis for clinicians","volume":"8","author":"Ando","year":"2013","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.ncl.2016.04.002_bib89","first-page":"1373","article-title":"Autonomic neuropathies","volume":"20","author":"Iodice","year":"2014","journal-title":"Continuum (Minneap Minn)"},{"issue":"7","key":"10.1016\/j.ncl.2016.04.002_bib90","first-page":"1","article-title":"Dopamine beta-hydroxylase deficiency","volume":"1","author":"Senard","year":"2006","journal-title":"Orphanet J Rare Dis"},{"issue":"6","key":"10.1016\/j.ncl.2016.04.002_bib91","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1002\/ana.10556","article-title":"The spectrum of autoimmune autonomic neuropathies","volume":"53","author":"Klein","year":"2003","journal-title":"Ann Neurol"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib92","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.autneu.2008.10.022","article-title":"Other autonomic neuropathies associated with ganglionic antibody","volume":"146","author":"Sandroni","year":"2009","journal-title":"Auton Neurosci"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib93","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.pediatrneurol.2010.05.003","article-title":"Isolated sympathetic failure with autoimmune autonomic ganglionopathy","volume":"43","author":"Fischer","year":"2010","journal-title":"Pediatr Neurol"},{"issue":"12","key":"10.1016\/j.ncl.2016.04.002_bib94","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1056\/NEJM200009213431204","article-title":"Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies","volume":"343","author":"Vernino","year":"2000","journal-title":"N\u00a0Engl J Med"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib95","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1111\/j.1460-9568.1994.tb00290.x","article-title":"Expression of neuronal nicotinic acetylcholine receptor subunit genes in the rat autonomic nervous system","volume":"6","author":"Rust","year":"1994","journal-title":"Eur J Neurosci"},{"issue":"23","key":"10.1016\/j.ncl.2016.04.002_bib96","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1212\/WNL.0b013e3181a92b52","article-title":"Efficacy of immunotherapy in seropositive and seronegative putative autoimmune autonomic ganglionopathy","volume":"72","author":"Iodice","year":"2009","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib97","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.autneu.2009.06.002","article-title":"Association of N-type calcium channel autoimmunity in patients with autoimmune autonomic ganglionopathy","volume":"150","author":"Kimpinski","year":"2009","journal-title":"Auton Neurosci"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib98","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1001\/archneur.61.1.44","article-title":"Idiopathic autonomic neuropathy: comparison of cases seropositive and seronegative for ganglionic acetylcholine receptor antibody","volume":"61","author":"Sandroni","year":"2004","journal-title":"Arch Neurol"},{"issue":"10","key":"10.1016\/j.ncl.2016.04.002_bib99","first-page":"2067","article-title":"The spectrum of clinicopathological features in pure autonomic neuropathy","volume":"259","author":"Koike","year":"2012","journal-title":"J\u00a0Neurol"},{"issue":"20","key":"10.1016\/j.ncl.2016.04.002_bib100","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1212\/01.wnl.0000312280.44805.5d","article-title":"Invited article: autonomic ganglia target and novel therapeutic tool","volume":"70","author":"Vernino","year":"2008","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.ncl.2016.04.002_bib101","first-page":"961","article-title":"Pure pandysautonomia associated with interferon-alpha therapy","volume":"254","author":"Yokote","year":"2007","journal-title":"J\u00a0Neurol"},{"issue":"15","key":"10.1016\/j.ncl.2016.04.002_bib102","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1056\/NEJMoa051719","article-title":"Plasma exchange for primary autoimmune autonomic failure","volume":"353","author":"Schroeder","year":"2005","journal-title":"N\u00a0Engl J Med"},{"issue":"9497","key":"10.1016\/j.ncl.2016.04.002_bib103","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1016\/S0140-6736(05)67665-9","article-title":"Guillain-Barre syndrome","volume":"366","author":"Hughes","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.ncl.2016.04.002_bib104","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1055\/s-2008-1062261","article-title":"Guillain-Barr\u00e9 syndrome","volume":"28","author":"Burns","year":"2008","journal-title":"Semin Neurol"},{"issue":"3","key":"10.1016\/j.ncl.2016.04.002_bib105","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s10286-009-0048-8","article-title":"Orthostatic hypotension as a presenting symptom of the Guillain\u2013Barr\u00e9 syndrome","volume":"20","author":"Zhang","year":"2010","journal-title":"Clin Auton Res"},{"issue":"6","key":"10.1016\/j.ncl.2016.04.002_bib106","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1002\/mus.23502","article-title":"Paraneoplastic neuromuscular disorders","volume":"46","author":"Sharp","year":"2012","journal-title":"Muscle Nerve"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib107","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10286-008-0488-6","article-title":"Antibody testing as a diagnostic tool in autonomic disorders","volume":"19","author":"Vernino","year":"2009","journal-title":"Clin Auton Res"},{"issue":"12","key":"10.1016\/j.ncl.2016.04.002_bib108","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11910-015-0599-0","article-title":"Clinical relevance of orthostatic hypotension in neurodegenerative disease","volume":"15","author":"McDonell","year":"2015","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib109","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S1566-0702(01)00374-5","article-title":"New findings on the neuropathology of multiple system atrophy","volume":"96","author":"Benarroch","year":"2002","journal-title":"Auton Neurosci"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib110","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jns.2011.09.030","article-title":"Autonomic involvement in Parkinson's disease: pathology, pathophysiology, clinical features and possible peripheral biomarkers","volume":"313","author":"Cersosimo","year":"2012","journal-title":"J\u00a0Neurol Sci"},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib111","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1600-0404.1995.tb00414.x","article-title":"Autonomic dysfunction in pathologically confirmed multiple system atrophy and idiopathic Parkinson's disease\u2013a retrospective comparison","volume":"91","author":"Magalhaes","year":"1995","journal-title":"Acta Neurol Scand"},{"issue":"2","key":"10.1016\/j.ncl.2016.04.002_bib112","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1007\/s004010050693","article-title":"The distribution of Lewy bodies in pure autonomic failure: autopsy findings and review of the literature","volume":"94","author":"Hague","year":"1997","journal-title":"Acta Neuropathol"},{"issue":"6","key":"10.1016\/j.ncl.2016.04.002_bib113","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1161\/01.HYP.0000188052.69549.e4","article-title":"Neurocirculatory abnormalities in Parkinson disease with orthostatic hypotension independence from levodopa treatment","volume":"46","author":"Goldstein","year":"2005","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib114","doi-asserted-by":"crossref","first-page":"H1768","DOI":"10.1152\/ajpheart.00287.2006","article-title":"Leg crossing improves orthostatic tolerance in healthy subjects: a placebo-controlled crossover study","volume":"291","author":"Krediet","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"25","key":"10.1016\/j.ncl.2016.04.002_bib115","first-page":"2162","article-title":"Orthostatic hypotension and orthostatic tachycardia: treatment with the head-up bed","volume":"115","author":"MacLean","year":"1940","journal-title":"J\u00a0Am Med Assoc"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib116","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1540-8159.2000.tb00833.x","article-title":"Tilt training: a treatment for malignant and recurrent neurocardiogenic syncope","volume":"23","author":"Reybrouck","year":"2000","journal-title":"Pacing Clin Electrophysiol"},{"issue":"6","key":"10.1016\/j.ncl.2016.04.002_bib117","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.jpeds.2006.07.031","article-title":"The efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope","volume":"149","author":"Qingyou","year":"2006","journal-title":"J\u00a0Pediatr"},{"issue":"28","key":"10.1016\/j.ncl.2016.04.002_bib118","first-page":"1951","article-title":"Efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope","volume":"89","author":"Liu","year":"2009","journal-title":"Zhonghua yi xue za zhi"},{"issue":"11","key":"10.1016\/j.ncl.2016.04.002_bib119","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1093\/europace\/eur200","article-title":"Effectiveness of midodrine treatment in patients with recurrent vasovagal syncope not responding to non-pharmacological treatment (STAND-trial)","volume":"13","author":"Romme","year":"2011","journal-title":"Europace"},{"issue":"13","key":"10.1016\/j.ncl.2016.04.002_bib120","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1212\/WNL.0000000000000815","article-title":"Midodrine for orthostatic hypotension and recurrent reflex syncope: a systematic review","volume":"83","author":"Izcovich","year":"2014","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/j.ncl.2016.04.002_bib121","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1161\/HYPERTENSIONAHA.114.04225","article-title":"Efficacy of atomoxetine versus midodrine for the treatment of orthostatic hypotension in autonomic failure","volume":"64","author":"Ramirez","year":"2014","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib122","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1001\/archneur.63.4.noc50340","article-title":"Pyridostigmine treatment trial in neurogenic orthostatic hypotension","volume":"63","author":"Singer","year":"2006","journal-title":"Arch Neurol"},{"issue":"1","key":"10.1016\/j.ncl.2016.04.002_bib123","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.autneu.2011.02.004","article-title":"Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome","volume":"161","author":"Freeman","year":"2011","journal-title":"Auton Neurosci"},{"issue":"4","key":"10.1016\/j.ncl.2016.04.002_bib124","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.pcad.2012.11.004","article-title":"Medical therapy and physical maneuvers in the treatment of the vasovagal syncope and orthostatic hypotension","volume":"55","author":"Raj","year":"2013","journal-title":"Prog Cardiovasc Dis"},{"issue":"9","key":"10.1016\/j.ncl.2016.04.002_bib125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11910-015-0583-8","article-title":"Postural tachycardia syndrome: beyond orthostatic intolerance","volume":"15","author":"Garland","year":"2015","journal-title":"Curr Neurol Neurosci Rep"}],"container-title":["Neurologic Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733861916300020?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733861916300020?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T07:47:14Z","timestamp":1692431234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0733861916300020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":125,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["S0733861916300020"],"URL":"https:\/\/doi.org\/10.1016\/j.ncl.2016.04.002","relation":{},"ISSN":["0733-8619"],"issn-type":[{"value":"0733-8619","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Syncope: Case Studies","name":"articletitle","label":"Article Title"},{"value":"Neurologic Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ncl.2016.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}