{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:03:12Z","timestamp":1792641792177,"version":"4.5.0"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T00:00:00Z","timestamp":1722384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Non-coding RNA Research"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.ncrna.2024.07.005","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T13:15:54Z","timestamp":1722431754000},"page":"163-176","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Mechanosensitive lncRNA H19 promotes chondrocyte autophagy, but not pyroptosis, by targeting miR-148a in post-traumatic osteoarthritis"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1390-7659","authenticated-orcid":false,"given":"Xuchang","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weizhong","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruobing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongxue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huili","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ShengYao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9181-8155","authenticated-orcid":false,"given":"Guoxin","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10182","key":"10.1016\/j.ncrna.2024.07.005_bib1","first-page":"1745","volume":"393","author":"Hunter","year":"2019","journal-title":"Osteoarthritis. Lancet"},{"issue":"3","key":"10.1016\/j.ncrna.2024.07.005_bib2","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.joca.2020.01.002","article-title":"Osteoarthritis year in review 2019: epidemiology and therapy","volume":"28","author":"Kloppenburg","year":"2020","journal-title":"Osteoarthritis Cartilage"},{"issue":"1","key":"10.1016\/j.ncrna.2024.07.005_bib3","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1038\/s41467-019-10439-y","article-title":"Functional testing of thousands of osteoarthritis-associated variants for regulatory activity","volume":"10","author":"Klein","year":"2019","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.ncrna.2024.07.005_bib4","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.csm.2017.02.001","article-title":"Basic science of articular cartilage","volume":"36","author":"Carballo","year":"2017","journal-title":"Clin. Sports Med."},{"key":"10.1016\/j.ncrna.2024.07.005_bib5","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.jmbbm.2018.10.023","article-title":"Shock absorbing ability in healthy and damaged cartilage-bone under high-rate compression","volume":"90","author":"Shaktivesh","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"1","key":"10.1016\/j.ncrna.2024.07.005_bib6","first-page":"39","article-title":"Mitochondrial genome sequencing of chondrocytes in osteoarthritis by human mitochondria RT2 Profiler\u2122 PCR array","volume":"6","author":"Li","year":"2012","journal-title":"Mol. Med. Rep."},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib7","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1080\/01926230701320337","article-title":"Apoptosis: a review of programmed cell death","volume":"35","author":"Elmore","year":"2007","journal-title":"Toxicol. Pathol."},{"issue":"3","key":"10.1016\/j.ncrna.2024.07.005_bib8","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1002\/jcp.21258","article-title":"Osteoarthritis","volume":"213","author":"Goldring","year":"2007","journal-title":"J. Cell. Physiol."},{"issue":"8","key":"10.1016\/j.ncrna.2024.07.005_bib9","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.joca.2009.03.002","article-title":"Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix","volume":"17","author":"Loeser","year":"2009","journal-title":"Osteoarthritis Cartilage"},{"issue":"2","key":"10.1016\/j.ncrna.2024.07.005_bib10","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.3390\/ijms24021710","article-title":"SDF-1\u03b1 promotes chondrocyte autophagy through CXCR4\/mTOR signaling axis","volume":"24","author":"Li","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ncrna.2024.07.005_bib11","unstructured":"Almonte-Becerril, M., et al., Cell Death of Chondrocytes Is a Combination between Apoptosis and Autophagy during the Pathogenesis of Osteoarthritis within an Experimental Model. (1573-675X (Electronic))."},{"key":"10.1016\/j.ncrna.2024.07.005_bib12","unstructured":"Debnath, J.A.-O., N. Gammoh, and K.A.-O. Ryan, Autophagy and Autophagy-Related Pathways in Cancer. (1471-0080 (Electronic))."},{"key":"10.1016\/j.ncrna.2024.07.005_bib13","unstructured":"Choi, I., et al., Autophagy Enables Microglia to Engage Amyloid Plaques and Prevents Microglial Senescence. (1476-4679 (Electronic))."},{"key":"10.1016\/j.ncrna.2024.07.005_bib14","unstructured":"Liu, Z., et al., Autophagy and Apoptosis: Regulatory Factors of Chondrocyte Phenotype Transition in Osteoarthritis. (1749-0774 (Electronic))."},{"key":"10.1016\/j.ncrna.2024.07.005_bib15","series-title":"Tougu Xiaotong Capsule Promotes Chondrocyte Autophagy by Regulating the Atg 12\/LC3 Conjugation Systems","first-page":"1791","author":"Li","year":"2014"},{"key":"10.1016\/j.ncrna.2024.07.005_bib16","unstructured":"Takayama K Fau - Kawakami, Y., et al., Local Intra-articular Injection of Rapamycin Delays Articular Cartilage Degeneration in a Murine Model of Osteoarthritis. (1478-6362 (Electronic))."},{"key":"10.1016\/j.ncrna.2024.07.005_bib17","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.omtn.2019.10.034","article-title":"Knockdown of GAS5 inhibits atherosclerosis progression via reducing EZH2-mediated ABCA1 transcription in ApoE(-\/-) mice","volume":"19","author":"Meng","year":"2020","journal-title":"Mol. Ther. Nucleic Acids"},{"issue":"3","key":"10.1016\/j.ncrna.2024.07.005_bib18","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ceb.2010.03.003","article-title":"Decoding the function of nuclear long non-coding RNAs","volume":"22","author":"Chen","year":"2010","journal-title":"Curr. Opin. Cell Biol."},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib19","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.cell.2009.02.006","article-title":"Evolution and functions of long noncoding RNAs","volume":"136","author":"Ponting","year":"2009","journal-title":"Cell"},{"issue":"8","key":"10.1016\/j.ncrna.2024.07.005_bib20","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1007\/s11626-018-0284-0","article-title":"LncRNA-uc.40 silence promotes P19 embryonic cells differentiation to cardiomyocyte via the PBX1 gene","volume":"54","author":"Wu","year":"2018","journal-title":"In Vitro Cell. Dev. Biol. Anim."},{"issue":"6181","key":"10.1016\/j.ncrna.2024.07.005_bib21","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1126\/science.1251456","article-title":"The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation","volume":"344","author":"Wang","year":"2014","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.ncrna.2024.07.005_bib22","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s13046-018-0747-x","article-title":"SP1-induced upregulation of lncRNA SPRY4-IT1 exerts oncogenic properties by scaffolding EZH2\/LSD1\/DNMT1 and sponging miR-101-3p in cholangiocarcinoma","volume":"37","author":"Xu","year":"2018","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"7520","key":"10.1016\/j.ncrna.2024.07.005_bib23","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/nature13596","article-title":"A long noncoding RNA protects the heart from pathological hypertrophy","volume":"514","author":"Han","year":"2014","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib24","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1002\/art.39520","article-title":"Long intergenic noncoding RNAs mediate the human chondrocyte inflammatory response and are differentially expressed in osteoarthritis cartilage","volume":"68","author":"Pearson","year":"2016","journal-title":"Arthritis Rheumatol."},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib25","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/os.12147","article-title":"Identification of long noncoding RNA associated with osteoarthritis in humans","volume":"6","author":"Xing","year":"2014","journal-title":"Orthop. Surg."},{"issue":"11","key":"10.1016\/j.ncrna.2024.07.005_bib26","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1089\/dna.2016.3397","article-title":"Long noncoding RNA UFC1 promotes proliferation of chondrocyte in osteoarthritis by acting as a sponge for miR-34a","volume":"35","author":"Zhang","year":"2016","journal-title":"DNA Cell Biol."},{"issue":"3","key":"10.1016\/j.ncrna.2024.07.005_bib27","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.bbrc.2018.04.130","article-title":"Long non-protein coding RNA DANCR functions as a competing endogenous RNA to regulate osteoarthritis progression via miR-577\/SphK2 axis","volume":"500","author":"Fan","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"6","key":"10.1016\/j.ncrna.2024.07.005_bib28","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/jvp.12306","article-title":"Pharmacokinetic comparison of oral tablet and suspension formulations of grapiprant, a novel therapeutic for the pain and inflammation of osteoarthritis in dogs","volume":"39","author":"Rausch-Derra","year":"2016","journal-title":"J. Vet. Pharmacol. Therapeut."},{"issue":"10","key":"10.1016\/j.ncrna.2024.07.005_bib29","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1007\/s00109-012-0895-y","article-title":"Regulation of H19 and its encoded microRNA-675 in osteoarthritis and under anabolic and catabolic in vitro conditions","volume":"90","author":"Steck","year":"2012","journal-title":"J. Mol. Med. (Berl.)"},{"issue":"8","key":"10.1016\/j.ncrna.2024.07.005_bib30","first-page":"2226","article-title":"H19 promotes the proliferation of osteocytes by inhibiting p53 during fracture healing","volume":"22","author":"Zhou","year":"2018","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"32","key":"10.1016\/j.ncrna.2024.07.005_bib31","doi-asserted-by":"crossref","first-page":"24381","DOI":"10.1074\/jbc.M110.111328","article-title":"Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes","volume":"285","author":"Dudek","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"8","key":"10.1016\/j.ncrna.2024.07.005_bib32","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1302\/2046-3758.118.BJR-2021-0188.R1","article-title":"Long noncoding RNA H19 alleviates inflammation in osteoarthritis through interactions between TP53, IL-38, and IL-36 receptor","volume":"11","author":"Zhou","year":"2022","journal-title":"Bone Joint Res"},{"issue":"6","key":"10.1016\/j.ncrna.2024.07.005_bib33","doi-asserted-by":"crossref","DOI":"10.1007\/s12038-019-9943-x","article-title":"Long non-coding RNA H19 modulates proliferation and apoptosis in osteoarthritis via regulating miR-106a-5p","volume":"44","author":"Zhang","year":"2019","journal-title":"J. Biosci."},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib34","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1007\/s10753-020-01227-8","article-title":"The fibroblast-like synoviocyte derived exosomal long non-coding RNA H19 alleviates osteoarthritis progression through the miR-106b-5p\/TIMP2 Axis","volume":"43","author":"Tan","year":"2020","journal-title":"Inflammation"},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib35","doi-asserted-by":"crossref","first-page":"381","DOI":"10.3349\/ymj.2019.60.4.381","article-title":"Knockdown of LncRNA H19 relieves LPS-induced damage by modulating miR-130a in osteoarthritis","volume":"60","author":"Hu","year":"2019","journal-title":"Yonsei Med. J."},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib36","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.21037\/apm-20-929","article-title":"Regulation of lncRNA-H19\/miR-140-5p in cartilage matrix degradation and calcification in osteoarthritis","volume":"9","author":"Yang","year":"2020","journal-title":"Ann. Palliat. Med."},{"issue":"5","key":"10.1016\/j.ncrna.2024.07.005_bib37","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1136\/annrheumdis-2021-221513","article-title":"Mechanical overloading promotes chondrocyte senescence and osteoarthritis development through downregulating FBXW7","volume":"81","author":"Zhang","year":"2022","journal-title":"Ann. Rheum. Dis."},{"issue":"11","key":"10.1016\/j.ncrna.2024.07.005_bib38","doi-asserted-by":"crossref","first-page":"7504","DOI":"10.1002\/jcp.30386","article-title":"Moderate mechanical stress suppresses the IL-1\u03b2-induced chondrocyte apoptosis by regulating mitochondrial dynamics","volume":"236","author":"Zhang","year":"2021","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.ncrna.2024.07.005_bib39","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1749-6632.2010.05808.x","article-title":"Mechanical loading, cartilage degradation, and arthritis","volume":"1211","author":"Sun","year":"2010","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib40","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1111\/j.1469-7580.2006.00546.x","article-title":"The effects of exercise on human articular cartilage","volume":"208","author":"Eckstein","year":"2006","journal-title":"J. Anat."},{"issue":"2","key":"10.1016\/j.ncrna.2024.07.005_bib41","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/01.bor.0000209426.84775.f8","article-title":"Epidemiology of osteoarthritis: an update","volume":"18","author":"Sharma","year":"2006","journal-title":"Curr. Opin. Rheumatol."},{"issue":"12","key":"10.1016\/j.ncrna.2024.07.005_bib42","first-page":"2507","article-title":"Prevalence of symptomatic knee, hand, and hip osteoarthritis in Greece. The ESORDIG study","volume":"33","author":"Andrianakos","year":"2006","journal-title":"J. Rheumatol."},{"issue":"3","key":"10.1016\/j.ncrna.2024.07.005_bib43","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/os.12321","article-title":"LncRNA-H19 modulates wnt\/\u03b2-catenin signaling by targeting Dkk4 in hindlimb unloaded rat","volume":"9","author":"Li","year":"2017","journal-title":"Orthop. Surg."},{"issue":"1","key":"10.1016\/j.ncrna.2024.07.005_bib44","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s12938-021-00949-6","article-title":"Moderate-intensity treadmill running relieves motion-induced post-traumatic osteoarthritis mice by up-regulating the expression of lncRNA H19","volume":"20","author":"Zhou","year":"2021","journal-title":"Biomed. Eng. Online"},{"issue":"1","key":"10.1016\/j.ncrna.2024.07.005_bib45","doi-asserted-by":"crossref","first-page":"50","DOI":"10.2174\/1871530319666190904161707","article-title":"LncRNA, important player in bone development and disease","volume":"20","author":"Li","year":"2020","journal-title":"Endocr., Metab. Immune Disord.: Drug Targets"},{"issue":"1","key":"10.1016\/j.ncrna.2024.07.005_bib46","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1186\/s13018-021-02501-7","article-title":"Treadmill running induces remodeling of the infrapatellar fat pad in an intensity-dependent manner","volume":"16","author":"Zeng","year":"2021","journal-title":"J. Orthop. Surg. Res."},{"key":"10.1016\/j.ncrna.2024.07.005_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.774681","article-title":"Cardiac effects of treadmill running at different intensities in a rat model","volume":"12","author":"Yan","year":"2021","journal-title":"Front. Physiol."},{"issue":"5","key":"10.1016\/j.ncrna.2024.07.005_bib48","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.berh.2018.03.003","article-title":"Osteoarthritis pain: what are we learning from animal models?","volume":"31","author":"Miller","year":"2017","journal-title":"Best Pract. Res. Clin. Rheumatol."},{"issue":"6","key":"10.1016\/j.ncrna.2024.07.005_bib49","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/acr.23013","article-title":"Efficacy of tailored exercise therapy on physical functioning in patients with knee osteoarthritis and comorbidity: a randomized controlled trial","volume":"69","author":"de Rooij","year":"2017","journal-title":"Arthritis Care Res."},{"issue":"11","key":"10.1016\/j.ncrna.2024.07.005_bib50","first-page":"1864","article-title":"Serine phosphorylation of insulin receptor substrate-1: a novel target for the reversal of insulin resistance","volume":"15","author":"Sykiotis","year":"2001","journal-title":"Mol. Endocrinol."},{"issue":"3","key":"10.1016\/j.ncrna.2024.07.005_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000245","article-title":"Can animal models of disease reliably inform human studies?","volume":"7","author":"van der Worp","year":"2010","journal-title":"PLoS Med."},{"issue":"1","key":"10.1016\/j.ncrna.2024.07.005_bib52","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.ejphar.2010.08.059","article-title":"Antihyperglycaemic, antilipid peroxidative and antioxidant effects of gallic acid on streptozotocin induced diabetic Wistar rats","volume":"650","author":"Punithavathi","year":"2011","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib53","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1177\/1759720X12437353","article-title":"Alterations in periarticular bone and cross talk between subchondral bone and articular cartilage in osteoarthritis","volume":"4","author":"Goldring","year":"2012","journal-title":"Ther Adv Musculoskelet Dis"},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib54","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1097\/BOR.0000000000000181","article-title":"Subchondral bone and osteoarthritis","volume":"27","author":"Funck-Brentano","year":"2015","journal-title":"Curr. Opin. Rheumatol."},{"issue":"9","key":"10.1016\/j.ncrna.2024.07.005_bib55","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.joca.2007.03.006","article-title":"The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129\/SvEv mouse","volume":"15","author":"Glasson","year":"2007","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.ncrna.2024.07.005_bib56","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.actbio.2021.09.035","article-title":"Positive interactions of mechanical loading and PTH treatments on spatio-temporal bone remodelling","volume":"136","author":"Cheong","year":"2021","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.ncrna.2024.07.005_bib57","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1186\/s13018-019-1307-6","article-title":"Icariin alleviates osteoarthritis by inhibiting NLRP3-mediated pyroptosis","volume":"14","author":"Zu","year":"2019","journal-title":"J. Orthop. Surg. Res."},{"issue":"10","key":"10.1016\/j.ncrna.2024.07.005_bib58","doi-asserted-by":"crossref","first-page":"7211","DOI":"10.1002\/jcp.30375","article-title":"The molecular structure and role of CCL2 (MCP-1) and C-C chemokine receptor CCR2 in skeletal biology and diseases","volume":"236","author":"Zhu","year":"2021","journal-title":"J. Cell. Physiol."},{"issue":"5","key":"10.1016\/j.ncrna.2024.07.005_bib59","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.14336\/AD.2019.1127","article-title":"Pyroptosis plays a role in osteoarthritis","volume":"11","author":"An","year":"2020","journal-title":"Aging Dis"},{"key":"10.1016\/j.ncrna.2024.07.005_bib60","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/1472567","article-title":"The overexpression of NALP3 inflammasome in knee osteoarthritis is associated with synovial membrane prolidase and NADPH oxidase 2","volume":"2016","author":"Clavijo-Cornejo","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.ncrna.2024.07.005_bib61","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/2165918","article-title":"Inhibition of synovial macrophage pyroptosis alleviates synovitis and fibrosis in knee osteoarthritis","volume":"2019","author":"Zhang","year":"2019","journal-title":"Mediat. Inflamm."},{"issue":"8","key":"10.1016\/j.ncrna.2024.07.005_bib62","doi-asserted-by":"crossref","DOI":"10.3390\/cells9081808","article-title":"The NLRP3 inflammasome: metabolic regulation and contribution to inflammaging","volume":"9","author":"Meyers","year":"2020","journal-title":"Cells"},{"issue":"4","key":"10.1016\/j.ncrna.2024.07.005_bib63","first-page":"5463","article-title":"NLRP1 and NLRP3 inflammasomes mediate LPS\/ATP-induced pyroptosis in knee osteoarthritis","volume":"17","author":"Zhao","year":"2018","journal-title":"Mol. Med. Rep."},{"issue":"6","key":"10.1016\/j.ncrna.2024.07.005_bib64","doi-asserted-by":"crossref","first-page":"5152","DOI":"10.18632\/aging.102937","article-title":"Rapamycin protects chondrocytes against IL-18-induced apoptosis and ameliorates rat osteoarthritis","volume":"12","author":"Bao","year":"2020","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.ncrna.2024.07.005_bib65","unstructured":"Liao, S., et al., HECTD1-Mediated Ubiquitination and Degradation of Rubicon Regulates Autophagy and Osteoarthritis Pathogenesis. (2326-5205 (Electronic))."},{"key":"10.1016\/j.ncrna.2024.07.005_bib66","unstructured":"Caram\u00e9s, B., et al., Autophagy Is a Protective Mechanism in Normal Cartilage, and its Aging-Related Loss Is Linked with Cell Death and Osteoarthritis. (1529-0131 (Electronic))."},{"key":"10.1016\/j.ncrna.2024.07.005_bib67","series-title":"lncRNA H19 Promotes Glioblastoma Multiforme Development by Activating Autophagy by Sponging miR-491-5p","first-page":"2165","author":"Wang","year":"2022"},{"issue":"3","key":"10.1016\/j.ncrna.2024.07.005_bib68","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1096\/fj.201600722R","article-title":"Long noncoding RNA H19 accelerates tenogenic differentiation and promotes tendon healing through targeting miR-29b-3p and activating TGF-\u03b21 signaling","volume":"31","author":"Lu","year":"2017","journal-title":"Faseb. J."},{"key":"10.1016\/j.ncrna.2024.07.005_bib69","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/8768327","article-title":"Metformin protects against oxidative stress injury induced by ischemia\/reperfusion via regulation of the lncRNA-H19\/miR-148a-3p\/Rock2 Axis","volume":"2019","author":"Zeng","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"10","key":"10.1016\/j.ncrna.2024.07.005_bib70","doi-asserted-by":"crossref","first-page":"11553","DOI":"10.18632\/oncotarget.7270","article-title":"Regulation of laryngeal squamous cell cancer progression by the lncRNA H19\/miR-148a-3p\/DNMT1 axis","volume":"7","author":"Wu","year":"2016","journal-title":"Oncotarget"},{"issue":"Suppl 7","key":"10.1016\/j.ncrna.2024.07.005_bib71","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1007\/s00508-016-1141-3","article-title":"MiR-148a the epigenetic regulator of bone homeostasis is increased in plasma of osteoporotic postmenopausal women","volume":"128","author":"Bedene","year":"2016","journal-title":"Wien Klin. Wochenschr."},{"issue":"5","key":"10.1016\/j.ncrna.2024.07.005_bib72","first-page":"2940","article-title":"Identification of differentially expressed microRNAs in the bone marrow of osteoporosis patients","volume":"11","author":"Gu","year":"2019","journal-title":"Am J Transl Res"},{"issue":"5","key":"10.1016\/j.ncrna.2024.07.005_bib73","doi-asserted-by":"crossref","first-page":"435","DOI":"10.2217\/rme-2020-0006","article-title":"microRNA-148a-3p-targeting p300 protects against osteoblast differentiation and osteoporotic bone reconstruction","volume":"16","author":"Liu","year":"2021","journal-title":"Regen. Med."},{"key":"10.1016\/j.ncrna.2024.07.005_bib74","article-title":"Biochemical signals mediate the crosstalk between cartilage and bone in osteoarthritis","volume":"2020","author":"Zhou","year":"2020","journal-title":"BioMed Res. Int."}],"container-title":["Non-coding RNA Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468054024001252?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468054024001252?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T06:30:35Z","timestamp":1741674635000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468054024001252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":74,"alternative-id":["S2468054024001252"],"URL":"https:\/\/doi.org\/10.1016\/j.ncrna.2024.07.005","relation":{},"ISSN":["2468-0540"],"issn-type":[{"value":"2468-0540","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mechanosensitive lncRNA H19 promotes chondrocyte autophagy, but not pyroptosis, by targeting miR-148a in post-traumatic osteoarthritis","name":"articletitle","label":"Article Title"},{"value":"Non-coding RNA Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ncrna.2024.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}