{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T16:17:39Z","timestamp":1776356259364,"version":"3.51.2"},"reference-count":49,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","theclinics.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurosurgery Clinics of North America"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.nec.2024.02.007","type":"journal-article","created":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T14:51:28Z","timestamp":1711032688000},"page":"355-361","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Developmental Venous Anomalies"],"prefix":"10.1016","volume":"35","author":[{"given":"Li","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samer S.","family":"Hoz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan A.","family":"Grossberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Lang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley A.","family":"Gross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.nec.2024.02.007_bib1","first-page":"715","article-title":"The natural history of intracranial venous angiomas","volume":"75","author":"Garner","year":"1991","journal-title":"J\u00a0Neurosurg"},{"issue":"1","key":"10.1016\/j.nec.2024.02.007_bib2","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1227\/00006123-199101000-00010","article-title":"Cavernous malformations and capillary telangiectasia: a spectrum within a single pathological entity","volume":"28","author":"Rigamonti","year":"1991","journal-title":"Neurosurgery"},{"issue":"5","key":"10.1016\/j.nec.2024.02.007_bib3","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/s00701-008-1570-5","article-title":"Developmental venous anomaly, cavernous malformation, and capillary telangiectasia: spectrum of a single disease","volume":"150","author":"Abla","year":"2008","journal-title":"Acta Neurochir (Wien)"},{"issue":"2","key":"10.1016\/j.nec.2024.02.007_bib4","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00006123-199808000-00001","article-title":"The prospective natural history of cerebral venous malformations","volume":"43","author":"McLaughlin","year":"1998","journal-title":"Neurosurgery"},{"issue":"4","key":"10.1016\/j.nec.2024.02.007_bib5","first-page":"531","article-title":"Radiosurgery for venous angiomas","volume":"78","author":"Lindquist","year":"1993","journal-title":"J\u00a0Neurosurg"},{"issue":"6","key":"10.1016\/j.nec.2024.02.007_bib6","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1161\/STROKEAHA.108.533034","article-title":"The presentation and clinical course of intracranial developmental venous anomalies in adults: a systematic review and prospective, population-based study","volume":"40","author":"Hon","year":"2009","journal-title":"Stroke"},{"issue":"12","key":"10.1016\/j.nec.2024.02.007_bib7","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1161\/STROKEAHA.108.521799","article-title":"Pathomechanisms of symptomatic developmental venous anomalies","volume":"39","author":"Pereira","year":"2008","journal-title":"Stroke"},{"issue":"3","key":"10.1016\/j.nec.2024.02.007_bib8","first-page":"458","article-title":"Aqueduct compression from venous angioma: MR findings","volume":"17","author":"Blackmore","year":"1996","journal-title":"AJNR Am J Neuroradiol"},{"issue":"6","key":"10.1016\/j.nec.2024.02.007_bib9","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.radcr.2020.02.014","article-title":"Obstructive hydrocephalus due to aqueductal stenosis from developmental venous anomaly draining bilateral medial thalami: a case report","volume":"15","author":"Xian","year":"2020","journal-title":"Radiol Case Rep"},{"issue":"9","key":"10.1016\/j.nec.2024.02.007_bib10","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1007\/s00381-017-3484-0","article-title":"Prevalence of cerebral cavernous malformations associated with developmental venous anomalies increases with age","volume":"33","author":"Brinjikji","year":"2017","journal-title":"Childs Nerv Syst"},{"issue":"2","key":"10.1016\/j.nec.2024.02.007_bib11","first-page":"570","article-title":"Correlation of the venous angioarchitecture of multiple cerebral cavernous malformations with familial or sporadic disease: a susceptibility-weighted imaging study with 7-Tesla MRI","volume":"126","author":"Dammann","year":"2017","journal-title":"J\u00a0Neurosurg"},{"issue":"2","key":"10.1016\/j.nec.2024.02.007_bib12","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1136\/jnnp-2012-302599","article-title":"The venous angioarchitecture of sporadic cerebral cavernous malformations: a susceptibility weighted imaging study at 7 T MRI","volume":"84","author":"Dammann","year":"2013","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"issue":"6","key":"10.1016\/j.nec.2024.02.007_bib13","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.ajhg.2015.11.011","article-title":"Somatic Activating PIK3CA Mutations Cause Venous Malformation","volume":"97","author":"Limaye","year":"2015","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.nec.2024.02.007_bib14","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/s44161-022-00035-7","article-title":"Developmental venous anomalies are a genetic primer for cerebral cavernous malformations","volume":"1","author":"Snellings","year":"2022","journal-title":"Nat Cardiovasc Res"},{"issue":"10","key":"10.1016\/j.nec.2024.02.007_bib15","doi-asserted-by":"crossref","first-page":"e856","DOI":"10.1212\/WNL.0000000000005066","article-title":"A\u00a0benchmark approach to hemorrhage risk management of cavernous malformations","volume":"90","author":"Kashefiolasl","year":"2018","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.nec.2024.02.007_bib16","first-page":"480","article-title":"Clinical course of untreated thalamic cavernous malformations: hemorrhage risk and neurological outcomes","volume":"127","author":"Tian","year":"2017","journal-title":"J\u00a0Neurosurg"},{"issue":"4","key":"10.1016\/j.nec.2024.02.007_bib17","first-page":"1079","article-title":"Hemorrhage from cerebral cavernous malformations: a systematic pooled analysis","volume":"126","author":"Gross","year":"2017","journal-title":"J\u00a0Neurosurg"},{"issue":"11","key":"10.1016\/j.nec.2024.02.007_bib18","doi-asserted-by":"crossref","first-page":"106101","DOI":"10.1016\/j.jstrokecerebrovasdis.2021.106101","article-title":"COVID-19 in a Hemorrhagic Neurovascular Disease, Cerebral Cavernous Malformation","volume":"30","author":"Shkoukani","year":"2021","journal-title":"J\u00a0Stroke Cerebrovasc Dis"},{"issue":"1","key":"10.1016\/j.nec.2024.02.007_bib19","doi-asserted-by":"crossref","first-page":"e89","DOI":"10.1212\/WNL.0000000000009730","article-title":"Hemorrhage from cerebral cavernous malformations: The role of associated developmental venous anomalies","volume":"95","author":"Chen","year":"2020","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.nec.2024.02.007_bib20","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1212\/WNL.0000000000009718","article-title":"Cavernous malformations with DVA: Hold those knives","volume":"95","author":"Rabinstein","year":"2020","journal-title":"Neurology"},{"issue":"9","key":"10.1016\/j.nec.2024.02.007_bib21","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.3174\/ajnr.A4352","article-title":"Increased Prevalence of Developmental Venous Anomalies in Children with Intracranial Neoplasms","volume":"36","author":"Jones","year":"2015","journal-title":"AJNR Am J Neuroradiol"},{"issue":"3","key":"10.1016\/j.nec.2024.02.007_bib22","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s00247-015-3525-3","article-title":"Developmental venous anomalies of the brain in children -- imaging spectrum and update","volume":"46","author":"Linscott","year":"2016","journal-title":"Pediatr Radiol"},{"issue":"2","key":"10.1016\/j.nec.2024.02.007_bib23","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s00062-013-0235-9","article-title":"Magnetic resonance imaging findings of developmental venous anomalies","volume":"24","author":"Gokce","year":"2014","journal-title":"Clin Neuroradiol"},{"issue":"7","key":"10.1016\/j.nec.2024.02.007_bib24","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1161\/STROKEAHA.116.016145","article-title":"Prevalence of Developmental Venous Anomalies Increases With Age","volume":"48","author":"Brinjikji","year":"2017","journal-title":"Stroke"},{"issue":"8","key":"10.1016\/j.nec.2024.02.007_bib25","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s00234-017-1867-2","article-title":"Sensitivity of susceptibility-weighted imaging in detecting developmental venous anomalies and associated cavernomas and microhemorrhages in children","volume":"59","author":"Young","year":"2017","journal-title":"Neuroradiology"},{"issue":"1\u20132","key":"10.1016\/j.nec.2024.02.007_bib26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jns.2009.08.064","article-title":"Susceptibility-weighted imaging for differential diagnosis of cerebral vascular pathology: a pictorial review","volume":"287","author":"Tsui","year":"2009","journal-title":"J\u00a0Neurol Sci"},{"issue":"1","key":"10.1016\/j.nec.2024.02.007_bib27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3174\/ajnr.A1400","article-title":"Susceptibility-weighted imaging: technical aspects and clinical applications, part 1","volume":"30","author":"Haacke","year":"2009","journal-title":"AJNR Am J Neuroradiol"},{"issue":"1","key":"10.1016\/j.nec.2024.02.007_bib28","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.nicl.2012.09.005","article-title":"Susceptibility-weighted imaging at 7 T: Improved diagnosis of cerebral cavernous malformations and associated developmental venous anomalies","volume":"1","author":"Frischer","year":"2012","journal-title":"Neuroimage Clin"},{"issue":"5","key":"10.1016\/j.nec.2024.02.007_bib29","doi-asserted-by":"crossref","first-page":"498","DOI":"10.3174\/ajnr.A7829","article-title":"Symptomatic Developmental Venous Anomaly: State-of-the-Art Review on Genetics, Pathophysiology, and Imaging Approach to Diagnosis","volume":"44","author":"Hsu","year":"2023","journal-title":"AJNR Am J Neuroradiol"},{"issue":"7","key":"10.1016\/j.nec.2024.02.007_bib30","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.3174\/ajnr.A1090","article-title":"Brain parenchymal signal abnormalities associated with developmental venous anomalies: detailed MR imaging assessment","volume":"29","author":"Santucci","year":"2008","journal-title":"AJNR Am J Neuroradiol"},{"issue":"3","key":"10.1016\/j.nec.2024.02.007_bib31","doi-asserted-by":"crossref","first-page":"475","DOI":"10.3174\/ajnr.A4172","article-title":"Brain metabolic abnormalities associated with developmental venous anomalies","volume":"36","author":"Larvie","year":"2015","journal-title":"AJNR Am J Neuroradiol"},{"issue":"4","key":"10.1016\/j.nec.2024.02.007_bib32","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.acra.2018.05.021","article-title":"Metabolic Changes of Brain Developmental Venous Anomalies on (18)F-FDG-PET","volume":"26","author":"Lazor","year":"2019","journal-title":"Acad Radiol"},{"issue":"5","key":"10.1016\/j.nec.2024.02.007_bib33","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/RLU.0000000000001594","article-title":"Glucose Hypometabolism in Developmental Venous Anomaly Without Apparent Parenchymal Damage","volume":"42","author":"Imai","year":"2017","journal-title":"Clin Nucl Med"},{"issue":"6","key":"10.1016\/j.nec.2024.02.007_bib34","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1212\/WNL.50.6.1709","article-title":"A\u00a0longitudinal study of patients with venous malformations: documentation of a negligible hemorrhage risk and benign natural history","volume":"50","author":"Naff","year":"1998","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.nec.2024.02.007_bib35","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3109\/02688697.2013.815318","article-title":"Surgical resection of developmental venous anomaly causing massive intracerebral haemorrhage: a case report","volume":"28","author":"Nagatani","year":"2014","journal-title":"Br J Neurosurg"},{"issue":"3","key":"10.1016\/j.nec.2024.02.007_bib36","first-page":"533","article-title":"Developmental venous anomaly with an arteriovenous shunt and a thrombotic complication. Case report","volume":"94","author":"Agazzi","year":"2001","journal-title":"J\u00a0Neurosurg"},{"issue":"9","key":"10.1016\/j.nec.2024.02.007_bib37","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1468-2982.2004.00768.x","article-title":"Subarachnoid haemorrhage headache from a developmental venous anomaly","volume":"24","author":"Lovrencic-Huzjan","year":"2004","journal-title":"Cephalalgia"},{"issue":"5","key":"10.1016\/j.nec.2024.02.007_bib38","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s002340050893","article-title":"The natural history of familial cerebral cavernomas: a retrospective MRI study of 40 patients","volume":"42","author":"Labauge","year":"2000","journal-title":"Neuroradiology"},{"issue":"4","key":"10.1016\/j.nec.2024.02.007_bib39","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1001\/archneur.1985.04060040077016","article-title":"Cerebellar venous angiomas. A continuing controversy","volume":"42","author":"Biller","year":"1985","journal-title":"Arch Neurol"},{"issue":"5","key":"10.1016\/j.nec.2024.02.007_bib40","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1002\/ana.20947","article-title":"Genotype-phenotype correlations in cerebral cavernous malformations patients","volume":"60","author":"Denier","year":"2006","journal-title":"Ann Neurol"},{"issue":"5","key":"10.1016\/j.nec.2024.02.007_bib41","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/0090-3019(88)90197-8","article-title":"Venous angiomas: an underestimated cause of intracranial hemorrhage","volume":"30","author":"Malik","year":"1988","journal-title":"Surg Neurol"},{"issue":"1","key":"10.1016\/j.nec.2024.02.007_bib42","first-page":"50","article-title":"Cavernous malformations of the brainstem: experience with 100 patients","volume":"90","author":"Porter","year":"1999","journal-title":"J\u00a0Neurosurg"},{"issue":"1","key":"10.1016\/j.nec.2024.02.007_bib43","first-page":"32","article-title":"Cavernous malformations of the brain stem","volume":"75","author":"Zimmerman","year":"1991","journal-title":"J\u00a0Neurosurg"},{"issue":"1\u20134","key":"10.1016\/j.nec.2024.02.007_bib44","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/BF01401979","article-title":"The association of venous and cavernous malformations. Report of four cases and discussion of the pathophysiological, diagnostic, and therapeutic implications","volume":"92","author":"Rigamonti","year":"1988","journal-title":"Acta Neurochir (Wien)"},{"issue":"3","key":"10.1016\/j.nec.2024.02.007_bib45","first-page":"461","article-title":"Excision of cavernous angioma with preservation of coexisting venous angioma. Case report","volume":"75","author":"Sasaki","year":"1991","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.nec.2024.02.007_bib46","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1227\/NEU.0b013e318226a069","article-title":"Cavernous malformations: a paradigm for progress","volume":"58","author":"Barrow","year":"2011","journal-title":"Clin Neurosurg"},{"issue":"3","key":"10.1016\/j.nec.2024.02.007_bib47","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1227\/NEU.0000000000000602","article-title":"Brainstem cavernous malformations: surgical results in 104 patients and a proposed grading system to predict neurological outcomes","volume":"76","author":"Garcia","year":"2015","journal-title":"Neurosurgery"},{"issue":"2023","key":"10.1016\/j.nec.2024.02.007_bib48","first-page":"002380","article-title":"Stereotactic radiosurgery for haemorrhagic cerebral cavernous malformation: a multi-institutional, retrospective study","volume":"svn","author":"Dumot","year":"2023","journal-title":"Stroke Vasc Neurol"},{"issue":"3","key":"10.1016\/j.nec.2024.02.007_bib49","first-page":"655","article-title":"Stereotactic radiosurgery for cerebral cavernous malformation: comparison of hemorrhage rates before and after stereotactic radiosurgery","volume":"136","author":"Karaaslan","year":"2022","journal-title":"J\u00a0Neurosurg"}],"container-title":["Neurosurgery Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1042368024000184?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1042368024000184?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T22:29:27Z","timestamp":1716330567000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1042368024000184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S1042368024000184"],"URL":"https:\/\/doi.org\/10.1016\/j.nec.2024.02.007","relation":{},"ISSN":["1042-3680"],"issn-type":[{"value":"1042-3680","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Developmental Venous Anomalies","name":"articletitle","label":"Article Title"},{"value":"Neurosurgery Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nec.2024.02.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}