{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T20:51:12Z","timestamp":1762375872565},"reference-count":48,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,8,26]],"date-time":"2014-08-26T00:00:00Z","timestamp":1409011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neoplasia"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.neo.2014.08.005","type":"journal-article","created":{"date-parts":[[2014,9,20]],"date-time":"2014-09-20T03:45:14Z","timestamp":1411184714000},"page":"741-750","source":"Crossref","is-referenced-by-count":5,"title":["The Novel C24D Synthetic Polypeptide Inhibits Binding of Placenta Immunosuppressive Ferritin to Human T Cells and Elicits Anti\u2013Breast Cancer Immunity In Vitro and In Vivo"],"prefix":"10.1016","volume":"16","author":[{"given":"Inna","family":"Solodeev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muayad A.","family":"Zahalka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaya","family":"Moroz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neo.2014.08.005_bb0005","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1053\/sonc.2002.33078","article-title":"Cancer immunotherapy: the interferon-alpha experience","volume":"29","author":"Kirkwood","year":"2002","journal-title":"Semin Oncol"},{"key":"10.1016\/j.neo.2014.08.005_bb0010","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1517\/14712598.8.8.1151","article-title":"Approved monoclonal antibodies for cancer therapy","volume":"8","author":"Boyiadzis","year":"2008","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.neo.2014.08.005_bb0015","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1007\/s00262-004-0523-y","article-title":"Targeting of tumor cells by lymphocytes engineered to express chimeric receptor genes","volume":"53","author":"Baxevanis","year":"2004","journal-title":"Cancer Immunol Immunother"},{"key":"10.1016\/j.neo.2014.08.005_bb0020","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1146\/annurev.med.56.062904.144915","article-title":"Aptamers: an emerging class of therapeutics","volume":"56","author":"Nimjee","year":"2005","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.neo.2014.08.005_bb0025","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.addr.2005.11.003","article-title":"Improved peptide vaccine strategies, creating synthetic artificial infections to maximize immune efficacy","volume":"58","author":"van der Burg","year":"2006","journal-title":"Adv Drug Deliv Rev"},{"issue":"Suppl 4","key":"10.1016\/j.neo.2014.08.005_bb0030","doi-asserted-by":"crossref","first-page":"S173","DOI":"10.3816\/CBC.2003.s.008","article-title":"Allogeneic breast cancer cell vaccines","volume":"3","author":"Dols","year":"2003","journal-title":"Clin Breast Cancer"},{"key":"10.1016\/j.neo.2014.08.005_bb0035","first-page":"30","article-title":"Ferritin on the surface of lymphocytes in Hodgkin's disease patients","volume":"29","author":"Moroz","year":"1977","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.neo.2014.08.005_bb0040","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1056\/NEJM197705192962017","article-title":"Lymphocytes bearing surface ferritin in patients with Hodgkin's disease and breast cancer","volume":"296","author":"Moroz","year":"1977","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neo.2014.08.005_bb0045","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0009-8981(85)90220-7","article-title":"Preparation and characterization of monoclonal antibodies specific to placenta ferritin","volume":"148","author":"Moroz","year":"1985","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.neo.2014.08.005_bb0050","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1471-0528.1996.tb09732.x","article-title":"Placental isoferritin: a new biomarker from conception to delivery","volume":"103","author":"Maymon","year":"1996","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.neo.2014.08.005_bb0055","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/1097-0142(19890801)64:3<691::AID-CNCR2820640321>3.0.CO;2-0","article-title":"The use of oncofetal ferritin-bearing lymphocytes as a marker for the screening, diagnosis, and follow-up of patients with early breast malignancy, screening of 3400 women","volume":"64","author":"Moroz","year":"1989","journal-title":"Cancer"},{"key":"10.1016\/j.neo.2014.08.005_bb0060","doi-asserted-by":"crossref","first-page":"12901","DOI":"10.1074\/jbc.M200956200","article-title":"PLIF, a novel human ferritin subunit from placenta with immunosuppressive activity","volume":"277","author":"Moroz","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neo.2014.08.005_bb0065","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1096\/fj.02-0960fje","article-title":"PLIF induces IL-10 production in monocytes: a calmodulin-p38 mitogen-activated protein kinase-dependent pathway","volume":"17","author":"Zahalka","year":"2003","journal-title":"FASEB J"},{"key":"10.1016\/j.neo.2014.08.005_bb0070","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/BF01807162","article-title":"Immunosuppression by breast cancer associated p43-effect of immunomodulators","volume":"41","author":"Rosen","year":"1996","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.neo.2014.08.005_bb0075","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0143-4004(96)90045-4","article-title":"Placental isoferritin as a marker of early abortion in pregnancies induced by in vitro fertilization","volume":"17","author":"Fisch","year":"1996","journal-title":"Placenta"},{"key":"10.1016\/j.neo.2014.08.005_bb0080","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1067\/mob.2000.104145","article-title":"Localization of p43 placental isoferritin in human maternal-fetal tissue interface","volume":"182","author":"Maymon","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.neo.2014.08.005_bb0085","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1093\/molehr\/6.9.843","article-title":"Detection of the immunoregulator p43-placental isoferritin in the human embryo and fetus","volume":"6","author":"Maymon","year":"2000","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.neo.2014.08.005_bb0090","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1053\/plac.1999.0491","article-title":"Diminished expression of placental isoferritin p43 component in first trimester abnormal pregnancies","volume":"21","author":"Jauniaux","year":"2000","journal-title":"Placenta"},{"key":"10.1016\/j.neo.2014.08.005_bb0095","first-page":"257","article-title":"Placental isoferritin as a physiological downregulator of cellular immunoreactivity during pregnancy","volume":"77","author":"Sirota","year":"1989","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.neo.2014.08.005_bb0100","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1600-0897.1993.tb00598.x","article-title":"Treatment of recurrent spontaneous abortions by immunization with paternal lymphocytes induces immunosuppression by placental isoferritin","volume":"30","author":"Moroz","year":"1993","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.neo.2014.08.005_bb0105","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1093\/humrep\/deh099","article-title":"Blocking of the placental immune-modulator PLIF activated Th1 type cytokines and affected placenta development, fetal growth and the pregnancy outcome","volume":"19","author":"Nahum","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.neo.2014.08.005_bb0110","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0304-3835(92)90006-H","article-title":"Expression of p43 in breast cancer tissue, correlation with prognostic parameters","volume":"67","author":"Rosen","year":"1992","journal-title":"Cancer Lett"},{"key":"10.1016\/j.neo.2014.08.005_bb0115","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1593\/neo.07259","article-title":"Antibodies to placental immunoregulatory ferritin with transfer of polyclonal lymphocytes arrest MCF-7 human breast cancer growth in a nude mouse model","volume":"9","author":"Halpern","year":"2007","journal-title":"Neoplasia"},{"key":"10.1016\/j.neo.2014.08.005_bb0120","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1093\/humrep\/dem011","article-title":"The use of Alamar Blue assay for quantitative analysis of viability, migration and invasion of choriocarcinoma cells","volume":"22","author":"Al-Nasiry","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.neo.2014.08.005_bb0125","first-page":"15","article-title":"The biochemical and cellular basis of cell proliferation assays that use tetrazolium salts","volume":"4","author":"Berridge","year":"1996","journal-title":"Biochemica"},{"key":"10.1016\/j.neo.2014.08.005_bb0130","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0022-1759(95)00072-I","article-title":"A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V","volume":"184","author":"Vermes","year":"1995","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.neo.2014.08.005_bb0135","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1002\/cyto.a.20048","article-title":"Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer","volume":"59","author":"George","year":"2004","journal-title":"Cytometry A"},{"key":"10.1016\/j.neo.2014.08.005_bb0140","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1182\/blood.V70.3.676.676","article-title":"Analysis of CD1 molecules on thymus cells and leukemic T lymphoblasts identifies discrete phenotypes and reveals that CD1 intermolecular complexes are observed only on normal cells","volume":"70","author":"Amiot","year":"1987","journal-title":"Blood"},{"key":"10.1016\/j.neo.2014.08.005_bb0145","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0014-5793(90)81380-7","article-title":"Specific binding of placental acidic isoferritin to cells of the T-cell line HD-MAR","volume":"263","author":"Konijn","year":"1990","journal-title":"FEBS Lett"},{"key":"10.1016\/j.neo.2014.08.005_bb0150","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1146\/annurev.iy.07.040189.003125","article-title":"Antigen recognition by class I-restricted T lymphocytes","volume":"7","author":"Townsend","year":"1989","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.neo.2014.08.005_bb0155","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/pros.20498","article-title":"Characterization of human prostate and breast cancer cell lines for experimental T cell-based immunotherapy","volume":"67","author":"Carlsson","year":"2007","journal-title":"Prostate"},{"key":"10.1016\/j.neo.2014.08.005_bb0160","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/S0198-8859(99)00124-X","article-title":"Isolation of broadly reactive, tumor-specific, HLA class-I restricted CTL from blood lymphocytes of a breast cancer patient","volume":"60","author":"Verdegaal","year":"1999","journal-title":"Hum Immunol"},{"key":"10.1016\/j.neo.2014.08.005_bb0165","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1146\/annurev.immunol.15.1.563","article-title":"The IFN-\u03b3 receptor: a paradigm for cytokine receptor signaling","volume":"15","author":"Bach","year":"1997","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.neo.2014.08.005_bb0170","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1146\/annurev.immunol.15.1.749","article-title":"Cellular responses to interferon-\u03b3","volume":"15","author":"Boehm","year":"1997","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.neo.2014.08.005_bb0175","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1126\/science.272.5262.719","article-title":"Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21WAF1\/CIP1 mediated by STAT1","volume":"272","author":"Chin","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.neo.2014.08.005_bb0180","doi-asserted-by":"crossref","first-page":"7673","DOI":"10.1073\/pnas.93.15.7673","article-title":"Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon \u03b1 and interferon \u03b3","volume":"93","author":"Bromberg","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neo.2014.08.005_bb0185","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1038\/nri1961","article-title":"Interferons, immunity and cancer immunoediting","volume":"6","author":"Dunn","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.neo.2014.08.005_bb0190","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1038\/nm1100","article-title":"Cancer immunotherapy: moving beyond current vaccines","volume":"10","author":"Rosenberg","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.neo.2014.08.005_bb0195","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1007\/s00262-008-0536-z","article-title":"Whole-cell cancer vaccination: from autologous to allogeneic tumor- and dendritic cell-based vaccines","volume":"57","author":"de Gruijl","year":"2008","journal-title":"Cancer Immunol Immunother"},{"key":"10.1016\/j.neo.2014.08.005_bb0200","first-page":"168","article-title":"Technical challenges facing therapeutic cancer vaccines","volume":"11","author":"Ward","year":"2008","journal-title":"Curr Opin Drug Discov Devel"},{"key":"10.1016\/j.neo.2014.08.005_bb0205","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1182\/blood-2008-06-165654","article-title":"Vaccination with autologous tumor-loaded dendritic cells induces clinical and immunologic responses in indolent B-cell lymphoma patients with relapsed and measurable disease: a pilot study","volume":"113","author":"Di Nicola","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.neo.2014.08.005_bb0210","first-page":"258","article-title":"New monoclonal antibody enzymoassay for the specific measurement of placental ferritin isotype in hematologic malignancies","volume":"15","author":"Moroz","year":"1987","journal-title":"Exp Hematol"},{"key":"10.1016\/j.neo.2014.08.005_bb0215","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00002030-198903010-00003","article-title":"Relation to clinical stage, CD8 lymphocyte binding and the pathogenesis of AIDS","volume":"3","author":"Moroz","year":"1989","journal-title":"AIDS"},{"key":"10.1016\/j.neo.2014.08.005_bb0220","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.exphem.2009.06.002","article-title":"A proof of concept study: Human C48-placenta immunoregulatory factor is an effective, single therapeutic agent enabling allogeneic, nonmanipulated murine bone marrow transplantation","volume":"37","author":"Moroz","year":"2009","journal-title":"Exp Hematol"},{"key":"10.1016\/j.neo.2014.08.005_bb0225","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/BF02990944","article-title":"FBL blood test as a predictive marker of breast cancer in high risk women","volume":"14","author":"Moroz","year":"1997","journal-title":"Med Oncol"},{"key":"10.1016\/j.neo.2014.08.005_bb0230","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0304-3835(91)90179-L","article-title":"Monoclonal antibody CM-H-9 detects circulating placental isoferritin in the serum of patients with visceral metastases of breast cancer","volume":"59","author":"Rosen","year":"1991","journal-title":"Cancer Lett"},{"key":"10.1016\/j.neo.2014.08.005_bb0235","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/BF01961165","article-title":"Placental isoferritin data from a pilot study","volume":"19","author":"Stierer","year":"1991","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.neo.2014.08.005_bb0240","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1038\/sj.bjc.6690434","article-title":"Identification of women with early breast cancer by analysis of p43-positive lymphocytes","volume":"80","author":"Auerbach","year":"1999","journal-title":"Br J Cancer"}],"container-title":["Neoplasia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1476558614001110?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1476558614001110?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T18:37:10Z","timestamp":1598294230000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1476558614001110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":48,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S1476558614001110"],"URL":"https:\/\/doi.org\/10.1016\/j.neo.2014.08.005","relation":{},"ISSN":["1476-5586"],"issn-type":[{"value":"1476-5586","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]}}}