{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T11:17:16Z","timestamp":1783250236657,"version":"3.54.6"},"reference-count":57,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,11]],"date-time":"2018-05-11T00:00:00Z","timestamp":1525996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institute of Health Research","doi-asserted-by":"crossref","award":["MOP106679"],"award-info":[{"award-number":["MOP106679"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Kristi Piia Callum Memorial Fellowship in Ovarian Cancer"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","journals.elsevierhealth.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neoplasia"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.neo.2018.05.005","type":"journal-article","created":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T17:23:38Z","timestamp":1527528218000},"page":"697-709","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["BRCA1 Mutation Status and Follicular Fluid Exposure Alters NF\u03baB Signaling and ISGylation in Human Fallopian Tube Epithelial Cells"],"prefix":"10.1016","volume":"20","author":[{"given":"Julia","family":"Hollingsworth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Tone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Kollara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Allen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terence J.","family":"Colgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Dube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry","family":"Rosen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Joan","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen M.","family":"Greenblatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3773-0018","authenticated-orcid":false,"given":"Tomer","family":"Feigenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl","family":"Virtanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore J.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neo.2018.05.005_bb0005","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/GCO.0b013e328011a21f","article-title":"The distal fallopian tube: a new model for pelvic serous carcinogenesis","volume":"19","author":"Crum","year":"2007","journal-title":"Curr Opin Obstet Gynecol"},{"key":"10.1016\/j.neo.2018.05.005_bb0010","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1200\/JCO.2006.09.1066","article-title":"Meta-analysis of BRCA1 and BRCA2 penetrance","volume":"25","author":"Chen","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.neo.2018.05.005_bb0015","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1126\/science.1088759","article-title":"Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2","volume":"302","author":"King","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.neo.2018.05.005_bb0020","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1093\/jnci\/djt095","article-title":"Cancer risks for BRCA1 and BRCA2 mutation carriers: results from prospective analysis of EMBRACE","volume":"105","author":"Mavaddat","year":"2013","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.neo.2018.05.005_bb0025","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1001\/jama.283.17.2260","article-title":"Clinicopathologic features of BRCA-linked and sporadic ovarian cancer","volume":"283","author":"Boyd","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.neo.2018.05.005_bb0030","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/AOG.0b013e318291c235","article-title":"Oral contraceptive pills as primary prevention for ovarian cancer: a systematic review and meta-analysis","volume":"122","author":"Havrilesky","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.neo.2018.05.005_bb0035","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/aje\/kwi046","article-title":"Effect of anovulation factors on pre- and postmenopausal ovarian cancer risk: revisiting the incessant ovulation hypothesis","volume":"161","author":"Tung","year":"2005","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.neo.2018.05.005_bb0040","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/aje\/kwh284","article-title":"Relation of contraceptive and reproductive history to ovarian cancer risk in carriers and noncarriers of BRCA1 gene mutations","volume":"160","author":"McGuire","year":"2004","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.neo.2018.05.005_bb0045","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S1470-2045(06)70983-4","article-title":"Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study","volume":"8","author":"McLaughlin","year":"2007","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.neo.2018.05.005_bb0050","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1093\/humrep\/14.1.162","article-title":"Cytokines in the follicular fluid of stimulated and non-stimulated human ovaries; is ovulation a suppressed inflammatory reaction?","volume":"14","author":"Buscher","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.neo.2018.05.005_bb0055","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.mce.2005.09.014","article-title":"Incessant ovulation, inflammation and epithelial ovarian carcinogenesis: revisiting old hypotheses","volume":"247","author":"Fleming","year":"2006","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.neo.2018.05.005_bb0060","doi-asserted-by":"crossref","first-page":"4067","DOI":"10.1158\/1078-0432.CCR-07-4959","article-title":"Gene expression profiles of luteal phase fallopian tube epithelium from BRCA mutation carriers resemble high-grade serous carcinoma","volume":"14","author":"Tone","year":"2008","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.neo.2018.05.005_bb0065","doi-asserted-by":"crossref","first-page":"4334","DOI":"10.1158\/1078-0432.CCR-12-0199","article-title":"Prolonged postovulatory proinflammatory signaling in the fallopian tube epithelium may be mediated through a BRCA1\/DAB2 axis","volume":"18","author":"Tone","year":"2012","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.neo.2018.05.005_bb0070","first-page":"2728","article-title":"Ex vivo culture of primary human fallopian tube epithelial cells","volume":"51","author":"Fotheringham","year":"2011","journal-title":"J Vis Exp"},{"key":"10.1016\/j.neo.2018.05.005_bb0075","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1002\/mrd.1046","article-title":"Establishment and characterization of an immortalized human oviductal cell line","volume":"59","author":"Lee","year":"2001","journal-title":"Mol Reprod Dev"},{"key":"10.1016\/j.neo.2018.05.005_bb0080","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1177\/1535370213508216","article-title":"Altered expression of inflammation-associated genes in oviductal cells following follicular fluid exposure: implications for ovarian carcinogenesis","volume":"239","author":"Lau","year":"2014","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1016\/j.neo.2018.05.005_bb0085","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.ygyno.2013.12.015","article-title":"Exposure of fallopian tube epithelium to follicular fluid mimics carcinogenic changes in precursor lesions of serous papillary carcinoma","volume":"132","author":"Bahar-Shany","year":"2014","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.neo.2018.05.005_bb0090","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/biostatistics\/kxj037","article-title":"Adjusting batch effects in microarray expression data using empirical Bayes methods","volume":"8","author":"Johnson","year":"2007","journal-title":"Biostatistics"},{"key":"10.1016\/j.neo.2018.05.005_bb0095","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res"},{"key":"10.1016\/j.neo.2018.05.005_bb0100","doi-asserted-by":"crossref","first-page":"7806","DOI":"10.1016\/S0021-9258(18)42585-9","article-title":"The interferon-inducible 15-kDa ubiquitin homolog conjugates to intracellular proteins","volume":"267","author":"Loeb","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neo.2018.05.005_bb0105","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1002\/path.4404","article-title":"Up-regulation of the interferon-related genes in BRCA2 knockout epithelial cells","volume":"234","author":"H","year":"2014","journal-title":"J Pathol"},{"key":"10.1016\/j.neo.2018.05.005_bb0110","doi-asserted-by":"crossref","first-page":"E613","DOI":"10.1073\/pnas.1115029109","article-title":"The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY","volume":"109","author":"Ezell","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"86","key":"10.1016\/j.neo.2018.05.005_bb0115","first-page":"1","article-title":"The complexity of NF-\u03baB signaling in inflammation and cancer","volume":"12","author":"Hoesel","year":"2013","journal-title":"Mol Cancer"},{"key":"10.1016\/j.neo.2018.05.005_bb0120","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.stem.2016.05.003","article-title":"Persistent Activation of NF-kappaB in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage","volume":"19","author":"Sau","year":"2016","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.neo.2018.05.005_bb0125","doi-asserted-by":"crossref","first-page":"26333","DOI":"10.1074\/jbc.M303076200","article-title":"BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65\/RelA subunit","volume":"278","author":"Benezra","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neo.2018.05.005_bb0130","doi-asserted-by":"crossref","first-page":"R30","DOI":"10.1186\/bcr2850","article-title":"Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice","volume":"13","author":"LN Burga","year":"2011","journal-title":"Breast Cancer Res"},{"key":"10.1016\/j.neo.2018.05.005_bb0135","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1756-9966-32-102","article-title":"Effect of BRCA1 on epidermal growth factor receptor in ovarian cancer","volume":"32","author":"Li","year":"2013","journal-title":"J Exp Clin Cancer Res"},{"key":"10.1016\/j.neo.2018.05.005_bb0140","doi-asserted-by":"crossref","first-page":"11721","DOI":"10.1073\/pnas.1412390111","article-title":"EGF receptor uses SOS1 to drive constitutive activation of NFkappaB in cancer cells","volume":"111","author":"De","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neo.2018.05.005_bb0145","doi-asserted-by":"crossref","first-page":"5232","DOI":"10.1038\/ncomms6232","article-title":"NF-kappaB-induced KIAA1199 promotes survival through EGFR signalling","volume":"5","author":"Shostak","year":"2014","journal-title":"Nat Commun"},{"key":"10.1016\/j.neo.2018.05.005_bb0150","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1038\/onc.2013.49","article-title":"Aberrant IKKalpha and IKKbeta cooperatively activate NF-kappaB and induce EGFR\/AP1 signaling to promote survival and migration of head and neck cancer","volume":"33","author":"Nottingham","year":"2014","journal-title":"Oncogene"},{"key":"10.1016\/j.neo.2018.05.005_bb0155","doi-asserted-by":"crossref","first-page":"8542","DOI":"10.1073\/pnas.97.15.8542","article-title":"Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells","volume":"97","author":"Biswas","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neo.2018.05.005_bb0160","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/pros.20234","article-title":"EGFR and Her-2 regulate the constitutive activation of NF-kappaB in PC-3 prostate cancer cells","volume":"65","author":"Le Page","year":"2005","journal-title":"Prostate"},{"key":"10.1016\/j.neo.2018.05.005_bb0165","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1158\/0008-5472.CAN-10-3626","article-title":"CARMA3 is crucial for EGFR-Induced activation of NF-kappaB and tumor progression","volume":"71","author":"Jiang","year":"2011","journal-title":"Cancer Res"},{"key":"10.1016\/j.neo.2018.05.005_bb0170","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s00109-006-0054-4","article-title":"Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinoma","volume":"84","author":"Lassus","year":"2006","journal-title":"J Mol Med (Berl)"},{"key":"10.1016\/j.neo.2018.05.005_bb0175","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1093\/jnci\/94.13.990","article-title":"Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers","volume":"94","author":"Jazaeri","year":"2002","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.neo.2018.05.005_bb0180","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1074\/mcp.M800460-MCP200","article-title":"Enhanced interferon signaling pathway in oral cancer revealed by quantitative proteome analysis of microdissected specimens using 16O\/18O labeling and integrated two-dimensional LC-ESI-MALDI tandem MS","volume":"8","author":"Chi","year":"2009","journal-title":"Mol Cell Proteomics"},{"key":"10.1016\/j.neo.2018.05.005_bb0185","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1038\/sj.bjc.6603099","article-title":"Stage-associated overexpression of the ubiquitin-like protein, ISG15, in bladder cancer","volume":"94","author":"Andersen","year":"2006","journal-title":"Br J Cancer"},{"key":"10.1016\/j.neo.2018.05.005_bb0190","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1038\/onc.2009.115","article-title":"Expression, regulation and function of the ISGylation system in prostate cancer","volume":"28","author":"Kiessling","year":"2009","journal-title":"Oncogene"},{"key":"10.1016\/j.neo.2018.05.005_bb0195","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0024291","article-title":"Interferon-beta signaling contributes to Ras transformation","volume":"6","author":"Tsai","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.neo.2018.05.005_bb0200","doi-asserted-by":"crossref","first-page":"e18","DOI":"10.1038\/emm.2013.36","article-title":"ISG15: leading a double life as a secreted molecule","volume":"45","author":"Bogunovic","year":"2013","journal-title":"Exp Mol Med"},{"key":"10.1016\/j.neo.2018.05.005_bb0205","doi-asserted-by":"crossref","first-page":"7221","DOI":"10.18632\/oncotarget.3372","article-title":"Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective","volume":"6","author":"Burks","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.neo.2018.05.005_bb0210","doi-asserted-by":"crossref","first-page":"4334","DOI":"10.1074\/jbc.M512830200","article-title":"Herc5, an interferon-induced HECT E3 enzyme, is required for conjugation of ISG15 in human cells","volume":"281","author":"Dastur","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neo.2018.05.005_bb0215","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1258\/ebm.2011.011236","article-title":"ISG15 disrupts cytoskeletal architecture and promotes motility in human breast cancer cells","volume":"237","author":"Desai","year":"2012","journal-title":"Exp Biol Med"},{"key":"10.1016\/j.neo.2018.05.005_bb0220","doi-asserted-by":"crossref","first-page":"14313","DOI":"10.1073\/pnas.1505690112","article-title":"Type I IFN induces protein ISGylation to enhance cytokine expression and augments colonic inflammation","volume":"112","author":"Fan","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neo.2018.05.005_bb0225","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/PGP.0b013e31827b25a2","article-title":"Interferon-stimulated gene, 15 kDa (ISG15) in ovarian high-grade serous carcinoma: prognostic impact and link to NF-kappaB pathway","volume":"33","author":"Darb-Esfahani","year":"2014","journal-title":"Int J Gynecol Pathol"},{"key":"10.1016\/j.neo.2018.05.005_bb0230","doi-asserted-by":"crossref","first-page":"6367","DOI":"10.1038\/sj.onc.1208797","article-title":"Gene expression analysis reveals a strong signature of an interferon-induced pathway in childhood lymphoblastic leukemia as well as in breast and ovarian cancer","volume":"24","author":"Einav","year":"2005","journal-title":"Oncogene"},{"key":"10.1016\/j.neo.2018.05.005_bb0235","doi-asserted-by":"crossref","first-page":"10200","DOI":"10.1073\/pnas.0504754102","article-title":"Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways","volume":"102","author":"Zhao","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neo.2018.05.005_bb0240","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s11010-012-1360-5","article-title":"Up-regulation of interferon-stimulated gene15 and its conjugates by tumor necrosis factor-alpha via type I interferon-dependent and -independent pathways","volume":"368","author":"Chairatvit","year":"2012","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.neo.2018.05.005_bb0245","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1248\/bpb.31.2223","article-title":"Regulation of the nuclear factor (NF)-kappaB pathway by ISGylation","volume":"31","author":"Minakawa","year":"2008","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.neo.2018.05.005_bb0250","doi-asserted-by":"crossref","first-page":"4521","DOI":"10.1016\/j.febslet.2006.07.032","article-title":"Negative regulation of protein phosphatase 2Cbeta by ISG15 conjugation","volume":"580","author":"Takeuchi","year":"2006","journal-title":"FEBS Lett"},{"key":"10.1016\/j.neo.2018.05.005_bb0255","doi-asserted-by":"crossref","first-page":"16608","DOI":"10.1074\/jbc.M208435200","article-title":"High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction","volume":"278","author":"Malakhov","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neo.2018.05.005_bb0260","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1128\/MCB.19.4.3029","article-title":"DE Zhang. A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation","volume":"19","author":"Liu","year":"1999","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.neo.2018.05.005_bb0265","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1158\/0008-5472.CAN-17-1752","article-title":"Evidence for the ISG15-Specific Deubiquitinase USP18 as an Antineoplastic Target","volume":"78","author":"Mustachio","year":"2018","journal-title":"Cancer Res"},{"key":"10.1016\/j.neo.2018.05.005_bb0270","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2016.326","article-title":"Multiple functions of USP18","volume":"7","author":"Honke","year":"2016","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.neo.2018.05.005_bb0275","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1111\/j.1440-1681.2011.05581.x","article-title":"A physiological concentration of glucocorticoid inhibits the pro-inflammatory cytokine-induced proliferation of adult rat cardiac fibroblasts: roles of extracellular signal-regulated kinase 1\/2 and nuclear factor-kappaB","volume":"38","author":"He","year":"2011","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.neo.2018.05.005_bb0280","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0103969","article-title":"Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia","volume":"9","author":"Lei","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.neo.2018.05.005_bb0285","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0036890","article-title":"Estrogen modulates NFkappaB signaling by enhancing IkappaBalpha levels and blocking p65 binding at the promoters of inflammatory genes via estrogen receptor-beta","volume":"7","author":"Xing","year":"2012","journal-title":"PLoS One"}],"container-title":["Neoplasia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S147655861830215X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S147655861830215X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T11:58:53Z","timestamp":1661342333000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S147655861830215X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":57,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["S147655861830215X"],"URL":"https:\/\/doi.org\/10.1016\/j.neo.2018.05.005","relation":{},"ISSN":["1476-5586"],"issn-type":[{"value":"1476-5586","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"BRCA1 Mutation Status and Follicular Fluid Exposure Alters NF\u03baB Signaling and ISGylation in Human Fallopian Tube Epithelial Cells","name":"articletitle","label":"Article Title"},{"value":"Neoplasia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neo.2018.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 <Employer>. Published by Elsevier Inc. on behalf of Neoplasia Press, Inc.","name":"copyright","label":"Copyright"}]}}