{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T23:43:27Z","timestamp":1793835807020,"version":"4.6.1"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T00:00:00Z","timestamp":1733184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neoplasia"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.neo.2024.101101","type":"journal-article","created":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T07:54:13Z","timestamp":1734162853000},"page":"101101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer"],"prefix":"10.1016","volume":"60","author":[{"given":"Fang","family":"Yuan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingmei","family":"Xuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4842-4650","authenticated-orcid":false,"given":"Rong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.neo.2024.101101_bib0001","doi-asserted-by":"crossref","first-page":"55","DOI":"10.14740\/wjon1254","article-title":"Esophageal cancer: an updated surveillance epidemiology and end results database analysis","volume":"11","author":"Then","year":"2020","journal-title":"World J. Oncol."},{"issue":"6","key":"10.1016\/j.neo.2024.101101_bib0002","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1007\/s12328-020-01237-x","article-title":"Epidemiology of esophageal cancer: update in global trends, etiology and risk factors","volume":"13","author":"Uhlenhopp","year":"2020","journal-title":"Clin. J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.neo.2024.101101_bib0003","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/nyas.14492","article-title":"Esophageal cancer surgery: review of complications and their management","volume":"1482","author":"Chevallay","year":"2020","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neo.2024.101101_bib0004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13019-020-01202-2","article-title":"The treatments and postoperative complications of esophageal cancer: a review","volume":"15","author":"Xu","year":"2020","journal-title":"J. Cardiothorac. Surg."},{"issue":"3","key":"10.1016\/j.neo.2024.101101_bib0005","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.21873\/anticanres.13259","article-title":"Early recurrence and cancer death after trimodal therapy for esophageal squamous cell carcinoma","volume":"39","author":"Hamai","year":"2019","journal-title":"Anticancer Res."},{"issue":"4","key":"10.1016\/j.neo.2024.101101_bib0006","doi-asserted-by":"crossref","first-page":"79","DOI":"10.21037\/atm.2017.11.28","article-title":"Advances in radiotherapy for esophageal cancer","volume":"6","author":"Deng","year":"2018","journal-title":"Ann. Transl. Med."},{"issue":"2","key":"10.1016\/j.neo.2024.101101_bib0007","doi-asserted-by":"crossref","first-page":"131","DOI":"10.21037\/acs.2017.03.03","article-title":"Overview of esophageal cancer","volume":"6","author":"Abbas","year":"2017","journal-title":"Ann. Cardiothorac. Surg."},{"issue":"11","key":"10.1016\/j.neo.2024.101101_bib0008","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.3390\/cancers11111789","article-title":"Ionizing radiation and complex DNA damage: from prediction to detection challenges and biological significance","volume":"11","author":"Mavragani","year":"2019","journal-title":"Cancers. (Basel)"},{"issue":"3","key":"10.1016\/j.neo.2024.101101_bib0009","doi-asserted-by":"crossref","first-page":"849","DOI":"10.21037\/jtd.2017.03.23","article-title":"The mechanisms of radioresistance in esophageal squamous cell carcinoma and current strategies in radiosensitivity","volume":"9","author":"Chen","year":"2017","journal-title":"J. Thorac. Dis."},{"issue":"3","key":"10.1016\/j.neo.2024.101101_bib0010","doi-asserted-by":"crossref","first-page":"181","DOI":"10.5483\/BMBRep.2019.52.3.048","article-title":"Deubiquitinating enzymes as cancer biomarkers: new therapeutic opportunities?","volume":"52","author":"Poondla","year":"2019","journal-title":"BMB Rep."},{"issue":"3","key":"10.1016\/j.neo.2024.101101_bib0011","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1159\/000443051","article-title":"Function of deubiquitinating enzyme USP14 as oncogene in different types of cancer","volume":"38","author":"Zhu","year":"2016","journal-title":"Cell. Physiol. Biochem."},{"issue":"8","key":"10.1016\/j.neo.2024.101101_bib0012","doi-asserted-by":"crossref","DOI":"10.1038\/oncsis.2013.28","article-title":"Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling","volume":"2","author":"Jung","year":"2013","journal-title":"Oncogenesis"},{"key":"10.1016\/j.neo.2024.101101_bib0013","doi-asserted-by":"crossref","first-page":"727","DOI":"10.3389\/fcell.2020.00727","article-title":"USP14 as a therapeutic target against neurodegeneration: a rat brain perspective","volume":"8","author":"Banerjee","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"issue":"8","key":"10.1016\/j.neo.2024.101101_bib0014","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1080\/15548627.2021.2002101","article-title":"Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy","volume":"18","author":"Ming","year":"2022","journal-title":"Autophagy"},{"issue":"7599","key":"10.1016\/j.neo.2024.101101_bib0015","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/nature17433","article-title":"USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites","volume":"532","author":"Lee","year":"2016","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.neo.2024.101101_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.prp.2019.152592","article-title":"CyclinB1 deubiquitination by USP14 regulates cell cycle progression in breast cancer","volume":"215","author":"Liu","year":"2019","journal-title":"Pathol.-Res. Pract."},{"issue":"9","key":"10.1016\/j.neo.2024.101101_bib0017","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1038\/s41419-021-04089-6","article-title":"USP14 maintains HIF1-\u03b1 stabilization via its deubiquitination activity in hepatocellular carcinoma","volume":"12","author":"Lv","year":"2021","journal-title":"Cell Death. Dis."},{"issue":"3","key":"10.1016\/j.neo.2024.101101_bib0018","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.bbrc.2020.01.150","article-title":"Ubiquitin-specific protease 14 regulates ovarian cancer cisplatin-resistance by stabilizing BCL6 oncoprotein","volume":"524","author":"Shen","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.neo.2024.101101_bib0019","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.biocel.2016.08.038","article-title":"Ubiquitin-specific protease 14 regulates cell proliferation and apoptosis in oral squamous cell carcinoma","volume":"79","author":"Chen","year":"2016","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"2","key":"10.1016\/j.neo.2024.101101_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2020.112385","article-title":"Ubiquitin-specific protease 14 promotes radio-resistance and suppresses autophagy in oral squamous cell carcinoma","volume":"398","author":"Xie","year":"2021","journal-title":"Exp. Cell Res."},{"issue":"17","key":"10.1016\/j.neo.2024.101101_bib0021","doi-asserted-by":"crossref","first-page":"4385","DOI":"10.3390\/cancers15174385","article-title":"USP14 positively modulates head and neck squamous carcinoma tumorigenesis and potentiates heat shock pathway through HSF1 stabilization","volume":"15","author":"Wang","year":"2023","journal-title":"Cancers. (Basel)"},{"issue":"5","key":"10.1016\/j.neo.2024.101101_bib0022","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1038\/s41418-023-01144-x","article-title":"Inhibition of USP14 promotes TNF\u03b1-induced cell death in head and neck squamous cell carcinoma (HNSCC)","volume":"30","author":"Morgan","year":"2023","journal-title":"Cell Death Differ."},{"issue":"17","key":"10.1016\/j.neo.2024.101101_bib0023","doi-asserted-by":"crossref","first-page":"6383","DOI":"10.3390\/ijms21176383","article-title":"USP14 regulates DNA damage response and is a target for radiosensitization in non-small cell lung cancer","volume":"21","author":"Sharma","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"11","key":"10.1016\/j.neo.2024.101101_bib0024","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1080\/15548627.2018.1496877","article-title":"USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination","volume":"14","author":"Sharma","year":"2018","journal-title":"Autophagy"},{"issue":"4","key":"10.1016\/j.neo.2024.101101_bib0025","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/1759-7714.12453","article-title":"Overexpression of ubiquitin specific peptidase 14 predicts unfavorable prognosis in esophageal squamous cell carcinoma","volume":"8","author":"Zhang","year":"2017","journal-title":"Thorac. Cancer"},{"issue":"1","key":"10.1016\/j.neo.2024.101101_bib0026","doi-asserted-by":"crossref","first-page":"114","DOI":"10.3390\/antiox13010114","article-title":"PKCiota inhibits the ferroptosis of esophageal cancer cells via suppressing USP14-mediated autophagic degradation of GPX4","volume":"13","author":"Tao","year":"2024","journal-title":"Antioxidants"},{"issue":"2","key":"10.1016\/j.neo.2024.101101_bib0027","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3727\/096504016X693164","article-title":"Knockdown of ubiquitin-specific protease 14 (USP14) inhibits the proliferation and tumorigenesis in esophageal squamous cell carcinoma cells","volume":"25","author":"Zhang","year":"2017","journal-title":"Oncol. Res."},{"issue":"1","key":"10.1016\/j.neo.2024.101101_bib0028","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s13046-024-03054-3","article-title":"CircPDE5A-encoded novel regulator of the PI3K\/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated de-ubiquitination of PIK3IP1","volume":"43","author":"Lei","year":"2024","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.neo.2024.101101_bib0029","article-title":"USP14: structure, function, and target inhibition","volume":"12","author":"Wang","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.neo.2024.101101_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13046-019-1227-7","article-title":"Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide","volume":"38","author":"Xia","year":"2019","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"22","key":"10.1016\/j.neo.2024.101101_bib0031","doi-asserted-by":"crossref","first-page":"9265","DOI":"10.1158\/0008-5472.CAN-10-1530","article-title":"Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis","volume":"70","author":"Kapuria","year":"2010","journal-title":"Cancer Res."},{"issue":"7","key":"10.1016\/j.neo.2024.101101_bib0032","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002783","article-title":"Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response","volume":"8","author":"Perry","year":"2012","journal-title":"PLoS Pathog."},{"issue":"7","key":"10.1016\/j.neo.2024.101101_bib0033","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1158\/1535-7163.MCT-10-0238","article-title":"Degrasyn potentiates the antitumor effects of bortezomib in mantle cell lymphoma cells in vitro and in vivo: therapeutic implications","volume":"9","author":"Pham","year":"2010","journal-title":"Mol. Cancer Ther."},{"issue":"8","key":"10.1016\/j.neo.2024.101101_bib0034","doi-asserted-by":"crossref","first-page":"3912","DOI":"10.1158\/0008-5472.CAN-06-4464","article-title":"Degrasyn activates proteasomal-dependent degradation of c-Myc","volume":"67","author":"Bartholomeusz","year":"2007","journal-title":"Cancer Res."},{"issue":"2","key":"10.1016\/j.neo.2024.101101_bib0035","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1111\/jcmm.14813","article-title":"Deubiquitinase inhibitor degrasyn suppresses metastasis by targeting USP5-WT1-E-cadherin signalling pathway in pancreatic ductal adenocarcinoma","volume":"24","author":"Li","year":"2020","journal-title":"J. Cell Mol. Med."},{"issue":"3","key":"10.1016\/j.neo.2024.101101_bib0036","doi-asserted-by":"crossref","first-page":"344","DOI":"10.3390\/cancers11030344","article-title":"WP1130 enhances TRAIL-induced apoptosis through USP9X-dependent miR-708-mediated downregulation of c-FLIP","volume":"11","author":"Kim","year":"2019","journal-title":"Cancers. (Basel)"},{"key":"10.1016\/j.neo.2024.101101_bib0037","doi-asserted-by":"crossref","first-page":"4779","DOI":"10.2147\/OTT.S203235","article-title":"Downregulation of H19 decreases the radioresistance in esophageal squamous cell carcinoma cells","volume":"12","author":"Luo","year":"2019","journal-title":"Onco Targets. Ther."},{"issue":"5","key":"10.1016\/j.neo.2024.101101_bib0038","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.3390\/molecules27051540","article-title":"DNA damage clustering after ionizing radiation and consequences in the processing of chromatin breaks","volume":"27","author":"Mladenova","year":"2022","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.neo.2024.101101_bib0039","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1128\/MCB.00581-08","article-title":"Death receptor-induced activation of the Chk2-and histone H2AX-associated DNA damage response pathways","volume":"29","author":"Solier","year":"2009","journal-title":"Mol. Cell Biol."},{"issue":"8","key":"10.1016\/j.neo.2024.101101_bib0040","doi-asserted-by":"crossref","DOI":"10.1128\/MCB.00472-17","article-title":"53BP1 mediates ATR-Chk1 signaling and protects replication forks under conditions of replication stress","volume":"38","author":"Her","year":"2018","journal-title":"Mol. Cell Biol."},{"issue":"7","key":"10.1016\/j.neo.2024.101101_bib0041","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/s41388-023-02923-z","article-title":"The Hippo-YAP signaling pathway drives CD24-mediated immune evasion in esophageal squamous cell carcinoma via macrophage phagocytosis","volume":"43","author":"Zhou","year":"2024","journal-title":"Oncogene"},{"key":"10.1016\/j.neo.2024.101101_bib0042","article-title":"Overexpression of YAP confers radioresistance to esophageal cancer by altering the tumor microenvironment","author":"Yao","year":"2024","journal-title":"Environ. Toxicol."},{"issue":"5","key":"10.1016\/j.neo.2024.101101_bib0043","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/s41416-024-02574-1","article-title":"GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14\/FASN axis and GPX4","volume":"130","author":"Chen","year":"2024","journal-title":"Br. J. Cancer"},{"issue":"22","key":"10.1016\/j.neo.2024.101101_bib0044","doi-asserted-by":"crossref","first-page":"12174","DOI":"10.1093\/nar\/gkad860","article-title":"Ubiquitin signaling and the proteasome drive human DNA\u2013protein crosslink repair","volume":"51","author":"Essawy","year":"2023","journal-title":"Nucl. Acids Res."},{"issue":"5","key":"10.1016\/j.neo.2024.101101_bib0045","first-page":"706","article-title":"A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance","volume":"123","author":"Tian","year":"2014","journal-title":"Blood J. Am. Soc. Hematol."},{"issue":"2","key":"10.1016\/j.neo.2024.101101_bib0046","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2016.477","article-title":"Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor","volume":"8","author":"Liao","year":"2017","journal-title":"Cell Death. Dis."},{"issue":"3","key":"10.1016\/j.neo.2024.101101_bib0047","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1159\/000478679","article-title":"The deubiquitinating enzyme USP14 regulates leukemic chemotherapy drugs-induced cell apoptosis by suppressing ubiquitination of Aurora kinase B","volume":"42","author":"Song","year":"2017","journal-title":"Cell. Physiol. Biochem."},{"issue":"15","key":"10.1016\/j.neo.2024.101101_bib0048","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.7150\/ijbs.47999","article-title":"IU1 suppresses proliferation of cervical cancer cells through MDM2 degradation","volume":"16","author":"Xu","year":"2020","journal-title":"Int. J. Biol. Sci."},{"issue":"1","key":"10.1016\/j.neo.2024.101101_bib0049","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1186\/s12935-023-03059-6","article-title":"Ubiquitin-specific peptidase 5 facilitates cancer stem cell-like properties in lung cancer by deubiquitinating \u03b2-catenin","volume":"23","author":"Tung","year":"2023","journal-title":"Cancer Cell Int."},{"issue":"12","key":"10.1016\/j.neo.2024.101101_bib0050","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1038\/s41422-018-0091-x","article-title":"Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade","volume":"28","author":"Wang","year":"2018","journal-title":"Cell Res."},{"key":"10.1016\/j.neo.2024.101101_bib0051","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.biochi.2018.10.006","article-title":"Stabilization of miRNAs in esophageal cancer contributes to radioresistance and limits efficacy of therapy","volume":"156","author":"Malhotra","year":"2019","journal-title":"Biochimie"},{"issue":"6","key":"10.1016\/j.neo.2024.101101_bib0052","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1080\/17512433.2017.1313112","article-title":"Overview of different available chemotherapy regimens combined with radiotherapy for the neoadjuvant and definitive treatment of esophageal cancer","volume":"10","author":"Tomasello","year":"2017","journal-title":"Expert. Rev. Clin. Pharmacol."},{"key":"10.1016\/j.neo.2024.101101_bib0053","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s10388-020-00782-1","article-title":"Multimodality approaches to control esophageal cancer: development of chemoradiotherapy, chemotherapy, and immunotherapy","volume":"18","author":"Kakeji","year":"2021","journal-title":"Esophagus"},{"issue":"10","key":"10.1016\/j.neo.2024.101101_bib0054","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.3390\/cells8101118","article-title":"The E-cadherin and N-cadherin switch in epithelial-to-mesenchymal transition: signaling, therapeutic implications, and challenges","volume":"8","author":"Loh","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.neo.2024.101101_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.dnarep.2021.103243","article-title":"Recent advances in \u03b3H2AX biomarker-based genotoxicity assays: a marker of DNA damage and repair","volume":"108","author":"Rahmanian","year":"2021","journal-title":"DNa Repair. (Amst)"},{"issue":"1","key":"10.1016\/j.neo.2024.101101_bib0056","doi-asserted-by":"crossref","first-page":"8255","DOI":"10.1038\/s41598-019-44771-6","article-title":"Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase","volume":"9","author":"Mladenov","year":"2019","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.neo.2024.101101_bib0057","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.7150\/ijbs.41246","article-title":"ATM expression is elevated in established radiation-resistant breast cancer cells and improves DNA repair efficiency","volume":"16","author":"Bian","year":"2020","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.neo.2024.101101_bib0058","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.dnarep.2018.11.008","article-title":"53BP1: a key player of DNA damage response with critical functions in cancer","volume":"73","author":"Mirza-Aghazadeh-Attari","year":"2019","journal-title":"DNa Repair. (Amst)"},{"issue":"1","key":"10.1016\/j.neo.2024.101101_bib0059","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.molcel.2016.08.002","article-title":"53BP1 integrates DNA repair and p53-dependent cell fate decisions via distinct mechanisms","volume":"64","author":"Cuella-Martin","year":"2016","journal-title":"Mol. Cell"},{"issue":"17","key":"10.1016\/j.neo.2024.101101_bib0060","doi-asserted-by":"crossref","first-page":"6383","DOI":"10.3390\/ijms21176383","article-title":"USP14 regulates DNA damage response and is a target for radiosensitization in non-small cell lung cancer","volume":"21","author":"Sharma","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.neo.2024.101101_bib0061","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1158\/1541-7786.MCR-14-0580","article-title":"A YAP\/TAZ-regulated molecular signature is associated with oral squamous cell carcinoma","volume":"13","author":"Hiemer","year":"2015","journal-title":"Mol. Cancer Res."},{"issue":"2","key":"10.1016\/j.neo.2024.101101_bib0062","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1007\/s13577-022-00669-6","article-title":"The role of YAP1 in small cell lung cancer","volume":"35","author":"Saito","year":"2022","journal-title":"Hum. Cell"},{"issue":"3","key":"10.1016\/j.neo.2024.101101_bib0063","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/2211-5463.12597","article-title":"YAP 1 overexpression is associated with poor prognosis of breast cancer patients and induces breast cancer cell growth by inhibiting PTEN","volume":"9","author":"Guo","year":"2019","journal-title":"FEBS Open. Bio"},{"issue":"16","key":"10.1016\/j.neo.2024.101101_bib0064","doi-asserted-by":"crossref","first-page":"7055","DOI":"10.1002\/cam4.2569","article-title":"SOX2 antagonizes WWC1 to drive YAP1 activation in esophageal squamous cell carcinoma","volume":"8","author":"Chai","year":"2019","journal-title":"Cancer Med."},{"issue":"4","key":"10.1016\/j.neo.2024.101101_bib0065","first-page":"2993","article-title":"Yesassociated protein (YAP) predicts poor prognosis and regulates progression of esophageal squamous cell cancer through epithelialmesenchymal transition","volume":"18","author":"Qu","year":"2019","journal-title":"Exp. Ther. Med."},{"issue":"58","key":"10.1016\/j.neo.2024.101101_bib0066","doi-asserted-by":"crossref","first-page":"98495","DOI":"10.18632\/oncotarget.21913","article-title":"YAP1 inhibition radiosensitizes triple negative breast cancer cells by targeting the DNA damage response and cell survival pathways","volume":"8","author":"Andrade","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.neo.2024.101101_bib0067","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.bbrc.2023.05.101","article-title":"YAP nuclear translocation facilitates radiation resistance in nasopharyngeal carcinoma cells","volume":"670","author":"Li","year":"2023","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.neo.2024.101101_bib0068","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1476-4598-13-110","article-title":"Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma","volume":"13","author":"Tu","year":"2014","journal-title":"Mol. Cancer"},{"issue":"8","key":"10.1016\/j.neo.2024.101101_bib0069","doi-asserted-by":"crossref","first-page":"4273","DOI":"10.1007\/s12035-023-03344-5","article-title":"Yap1-Usp14 axis inhibits neuronal mitophagy during neonatal hypoxia\u2013ischemia encephalopathy by regulation of beclin-1 ubiquitination in mouse","volume":"60","author":"Lin","year":"2023","journal-title":"Mol. Neurobiol."}],"container-title":["Neoplasia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1476558624001428?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1476558624001428?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T03:45:31Z","timestamp":1741059931000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1476558624001428"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":69,"alternative-id":["S1476558624001428"],"URL":"https:\/\/doi.org\/10.1016\/j.neo.2024.101101","relation":{},"ISSN":["1476-5586"],"issn-type":[{"value":"1476-5586","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer","name":"articletitle","label":"Article Title"},{"value":"Neoplasia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neo.2024.101101","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"101101"}}