{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:35:58Z","timestamp":1791275758122,"version":"4.1.0"},"reference-count":52,"publisher":"JLE","issue":"6","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["N\u00e9phrologie & Th\u00e9rapeutique"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.nephro.2014.09.001","type":"journal-article","created":{"date-parts":[[2014,10,16]],"date-time":"2014-10-16T14:05:51Z","timestamp":1413468351000},"page":"479-483","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Aspects actuels des rejets aigus humoraux"],"prefix":"10.1684","volume":"10","author":[{"given":"Christophe","family":"Legendre","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Loupy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Rabant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Aubert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9mentine","family":"Rabat\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Delville","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Tinel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucile","family":"Amrouche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Snanoudj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynda","family":"Bererhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Scemla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9becca","family":"Sberro-Soussan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Paul","family":"Duong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Suberbielle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dany","family":"Anglicheau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18929","reference":[{"key":"10.1016\/j.nephro.2014.09.001_bib0005","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1034\/j.1600-6143.2003.00072.x","article-title":"Antibody-mediated rejection criteria\u00a0\u2013\u00a0an addition to the Banff 97\u00a0classification of renal allograft rejection","volume":"3","author":"Racusen","year":"2003","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0010","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/j.1365-2249.1991.tb02954.x","article-title":"Vascular deposition of complement-split products in kidney allografts with cell-mediated rejection","volume":"86","author":"Feucht","year":"1991","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0015","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1111\/ajt.12807","article-title":"HLA antibody detection with solid phase assays: great expectations or expectations too great","volume":"14","author":"Gebel","year":"2014","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0020","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/ajt.12589","article-title":"Diagnosis and management of antibody-mediated rejection: current status and novel approaches","volume":"14","author":"Djamali","year":"2014","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0025","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1111\/j.1600-6143.2006.01657.x","article-title":"Subclinical acute antibody-mediated rejection in positive cross-match renal allografts","volume":"7","author":"Haas","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-6143.2008.02262.x","article-title":"The spectrum of antibody-mediated renal allograft injury: implications for treatment","volume":"8","author":"Gloor","year":"2008","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0035","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/nrneph.2012.81","article-title":"The impact of donor-specific anti-HLA antibodies on late kidney allograft failure","volume":"8","author":"Loupy","year":"2012","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0040","first-page":"42","article-title":"The detection of antigenic differences in mouse erythrocytes by the employment of immune sera","volume":"17","author":"Gorer","year":"1936","journal-title":"Br J exp Pathol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0045","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/path.1700470204","article-title":"The antigenic basis of tumor transplantation","volume":"47","author":"Gorer","year":"1938","journal-title":"J Pathol Bacteriol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0050","first-page":"142","article-title":"The cytotoxic activity of isoantibodies in mice","volume":"3","author":"Gorer","year":"1956","journal-title":"Transplant Bull"},{"key":"10.1016\/j.nephro.2014.09.001_bib0055","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1159\/000205478","article-title":"Iso-leuco-anticorps","volume":"20","author":"Dausset","year":"1958","journal-title":"Acta Hematol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0060","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1038\/1811735a0","article-title":"Leucocyte antibodies in sera of pregnant women","volume":"181","author":"van Rood","year":"1958","journal-title":"Nature"},{"key":"10.1016\/j.nephro.2014.09.001_bib0065","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/S0140-6736(66)92829-7","article-title":"Hyperacute rejection of kidney allografts associated with preexisting humoral antibodies against donor cells","volume":"2","author":"Kissmeyer-Nielsen","year":"1966","journal-title":"Lancet"},{"key":"10.1016\/j.nephro.2014.09.001_bib0070","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1056\/NEJM196904032801401","article-title":"Significance of the positive crossmatch test in kidney transplantation","volume":"280","author":"Patel","year":"1969","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nephro.2014.09.001_bib0075","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1056\/NEJM197001152820301","article-title":"Humoral antibodies in renal allotransplantation in man","volume":"282","author":"Jeannet","year":"1970","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nephro.2014.09.001_bib0080","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/ki.1993.187","article-title":"Capillary deposition of C4d complement fragment and early renal graft loss","volume":"43","author":"Feucht","year":"1993","journal-title":"Kidney Int"},{"key":"10.1016\/j.nephro.2014.09.001_bib0085","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1097\/00007890-199203000-00011","article-title":"The significance of the anti-class I response. II. Clinical and pathological features of renal transplants with anti-class I-like antibody","volume":"53","author":"Halloran","year":"1992","journal-title":"Transplantation"},{"key":"10.1016\/j.nephro.2014.09.001_bib0090","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/00007890-199001000-00019","article-title":"The significance of the anti-class I response. I.\u00a0Clinical and pathological features of anti-class I-mediated rejection","volume":"49","author":"Halloran","year":"1990","journal-title":"Transplantation"},{"key":"10.1016\/j.nephro.2014.09.001_bib0095","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1097\/00007890-199606150-00007","article-title":"Pathologic features of acute renal allograft rejection associated with donor-specific antibody. Analysis using the Banff grading schema","volume":"61","author":"Trpkov","year":"1996","journal-title":"Transplantation"},{"key":"10.1016\/j.nephro.2014.09.001_bib0100","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1111\/j.1600-6143.2007.01924.x","article-title":"SWOT analysis of Banff: strenghts, weaknesses, opportunities and threats of the International Banff Consensus Process and Classification system for renal allograft pathology","volume":"7","author":"Mengel","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0105","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/ki.1993.259","article-title":"International standardization of criteria for the histologic diagnosis of renal allograft rejection: the Banff working classification of kidney transplant pathology","volume":"44","author":"Solez","year":"1993","journal-title":"Kidney Int"},{"key":"10.1016\/j.nephro.2014.09.001_bib0110","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1046\/j.1523-1755.1999.00299.x","article-title":"The Banff 97\u00a0working classification of renal allograft pathology","volume":"55","author":"Racusen","year":"1999","journal-title":"Kidney Int"},{"key":"10.1016\/j.nephro.2014.09.001_bib0115","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1681\/ASN.V10102208","article-title":"Complement activation in acute humoral renal allograft rejection: diagnostic significance of C4d deposits in peritubular capillaries","volume":"10","author":"Collins","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0120","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1093\/ndt\/16.10.2058","article-title":"Endothelial C4d deposition is associated with inferior kidney allograft outcome independently of cellular rejection","volume":"16","author":"Regele","year":"2001","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0125","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/00041552-200211000-00007","article-title":"Humoral rejection in kidney transplantation: new concepts in diagnosis and treatment","volume":"11","author":"Mauiyyedi","year":"2002","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.nephro.2014.09.001_bib0130","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1097\/01.ASN.0000029941.34837.22","article-title":"Capillary C4d deposition as a marker of humoral immunity in renal allograft rejection","volume":"13","author":"Watschinger","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0135","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1681\/ASN.V131234","article-title":"C4d deposition in acute rejection: an independent long-term prognostic factor","volume":"13","author":"Herzenber","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0140","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1681\/ASN.V131242","article-title":"Detection of the complement degradation product C4d in renal allografts: diagnostic and therapeutic implications","volume":"13","author":"Nickeleit","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0145","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1681\/ASN.V1341091","article-title":"Capillary C4d deposition in kidney allografts: a specific marker of alloantibody-dependent graft injury","volume":"13","author":"B\u00f6hmig","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0150","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1034\/j.1600-6143.2003.00172.x","article-title":"The clinical importance of alloantibody-mediated rejection","volume":"3","author":"Halloran","year":"2003","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0155","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1111\/j.1600-6143.2005.01086.x","article-title":"Humoral rejection of organ allografts","volume":"5","author":"Moll","year":"2005","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0160","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1681\/ASN.2007010073","article-title":"Antibody-mediated renal allograft rejection: diagnosis and pathogenesis","volume":"18","author":"Colvin","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0165","first-page":"646","article-title":"Complement C4d in graft capillaries","volume":"3","author":"Feucht","year":"2003","journal-title":"The missing link in the recognition of humoral alloreactivity. Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0170","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.humpath.2005.08.002","article-title":"Comparative study for the detection of peritubular capillary C4d deposition in human renal allografts using different methodologies","volume":"36","author":"Nadasdy","year":"2005","journal-title":"Hum Pathol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0175","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1056\/NEJMoa035717","article-title":"Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection","volume":"352","author":"Dragun","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nephro.2014.09.001_bib0180","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1111\/j.1600-6143.2007.01752.x","article-title":"Posttransplant prophylactic intravenous immunoglobulin in kidney transplant patients at high immunological risk: a pilot study","volume":"7","author":"Anglicheau","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0185","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1111\/j.1600-6143.2009.02813.x","article-title":"Outcome of subclinical antibody-mediated rejection in kidney transpant recipiens with preformed donor-specific antibodies","volume":"9","author":"Loupy","year":"2009","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0190","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1111\/j.1600-6143.2009.02761.x","article-title":"Endothelial gene expression in kidney transplants with alloantibody indicates antibody-mediated damage despite lack of C4d staining","volume":"9","author":"Sis","year":"2009","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0195","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1600-6143.2010.03364.x","article-title":"Significance of C4d Banff scores in early protocol biopsies of kidney transplant recipients with preformed donor-specific antibodies (DSA)","volume":"11","author":"Loupy","year":"2011","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0200","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0140-6736(12)61265-3","article-title":"Antibody-mediated vascular rejection of kidney allografts: a population-based study","volume":"381","author":"Lefaucheur","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.nephro.2014.09.001_bib0205","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/ajt.12590","article-title":"Banff 2013\u00a0meeting report: inclusion of C4d-negative antibody-mediated rejection and antibody-associated arterial lesions","volume":"14","author":"Haas","year":"2014","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0210","first-page":"4179","article-title":"Antibodies in transplantation: the effects of HLA and non-HLA antibody binding and mechanisms of injury","volume":"1034","author":"Valenzuela","year":"2013","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0215","first-page":"394","article-title":"Detection of donor-specific anti-HLA antibodies with flow cytometry in eluates and sera from renal transplant recipients with chronic allograft nephropathy","volume":"76","author":"Martin","year":"2005","journal-title":"Transplantation"},{"key":"10.1016\/j.nephro.2014.09.001_bib0220","doi-asserted-by":"crossref","first-page":"2855","DOI":"10.1111\/ajt.12438","article-title":"Kidney intragraft donor-specific antibodies as determinant of antibody-mediated lesions and poor graft outcome","volume":"13","author":"Bachelet","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0225","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1111\/ajt.12150","article-title":"Molecular diagnosis of antibody-mediated rejection in human kidney transplants","volume":"13","author":"Sellares","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0230","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1038\/nrneph.2010.113","article-title":"Molecular diagnostics in transplantation","volume":"6","author":"Naesens","year":"2010","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.nephro.2014.09.001_bib0235","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1111\/ajt.12397","article-title":"Pretransplant sensitization against angiotensin II type 1\u00a0receptor is a risk factor for acute rejection and graft loss","volume":"13","author":"Giral","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0240","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1111\/ajt.12395","article-title":"Higher risk of kidney graft failure in the presence of anti-angiotensin II type-1\u00a0receptor antbodies","volume":"13","author":"Taniguchi","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1016\/j.nephro.2014.09.001_bib0245","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1097\/01.tp.0000231348.55262.5a","article-title":"Endothelial cells as targets of allograft rejection","volume":"82","author":"Glotz","year":"2006","journal-title":"Transplantation"},{"key":"10.1016\/j.nephro.2014.09.001_bib0250","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1056\/NEJMoa067160","article-title":"Antibodies against MICA antigens and kidney-transplant rejection","volume":"357","author":"Zou","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nephro.2014.09.001_bib0255","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1016\/S0140-6736(05)66458-6","article-title":"Non-HLA transplantation immunity revealed by lymphocytotoxic antibodies","volume":"365","author":"Opelz","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.nephro.2014.09.001_bib0260","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/TP.0b013e31825d1587","article-title":"The treatment of acute antibody-mediated rejection in kidney transplant recipients\u2013a systematic review","volume":"94","author":"Roberts","year":"2012","journal-title":"Transplantation"}],"container-title":["N\u00e9phrologie & Th\u00e9rapeutique"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1769725514006142?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1769725514006142?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jle.com\/10.1016\/j.nephro.2014.09.001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T15:16:42Z","timestamp":1741187802000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1769725514006142"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":52,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S1769725514006142"],"URL":"https:\/\/doi.org\/10.1016\/j.nephro.2014.09.001","relation":{},"ISSN":["1769-7255"],"issn-type":[{"value":"1769-7255","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aspects actuels des rejets aigus humoraux","name":"articletitle","label":"Article Title"},{"value":"N\u00e9phrologie & Th\u00e9rapeutique","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nephro.2014.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Association Soci\u00e9t\u00e9 de n\u00e9phrologie. Published by Elsevier Masson SAS All rights reserved.","name":"copyright","label":"Copyright"}]}}