{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T11:10:13Z","timestamp":1775560213287,"version":"3.50.1"},"reference-count":84,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience & Biobehavioral Reviews"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.neubiorev.2017.08.009","type":"journal-article","created":{"date-parts":[[2017,8,19]],"date-time":"2017-08-19T12:00:37Z","timestamp":1503144037000},"page":"368-375","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Gluten related illnesses and severe mental disorders: a comprehensive review"],"prefix":"10.1016","volume":"84","author":[{"given":"Elisa","family":"Brietzke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael O.","family":"Cerqueira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo B.","family":"Mansur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger S.","family":"McIntyre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neubiorev.2017.08.009_bib0005","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.pediatrneurol.2006.11.011","article-title":"Increased prevalence of silent celiac disease among Greek epileptic children","volume":"36","author":"Antigoni","year":"2007","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0010","doi-asserted-by":"crossref","first-page":"751","DOI":"10.17219\/acem\/43585","article-title":"Celiac disease and epilepsy: the effect of gluten-free diet on seizure control","volume":"25","author":"Bashiri","year":"2016","journal-title":"Adv. Clin. Exp. Med."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0015","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/BF01562517","article-title":"Childhood schizophrenia","volume":"27","author":"Bender","year":"1953","journal-title":"Psychiatr. Q."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0020","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1176\/appi.ajp.2011.11030516","article-title":"Autoimmune diseases and severe infections as risk factors for schizophrenia: a 30-year population-based register study","volume":"168","author":"Benros","year":"2011","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0025","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1001\/jamapsychiatry.2013.1111","article-title":"Autoimmune diseases and severe infections as risk factors for mood disorders: a nationwide study","volume":"70","author":"Benros","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0030","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s12016-010-8223-1","article-title":"Cutting-edge issues in celiac disease and in gluten intolerance","volume":"42","author":"Bizzaro","year":"2012","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0035","doi-asserted-by":"crossref","DOI":"10.3389\/fnhum.2016.00130","article-title":"Bread and other edible agents of mental disease","volume":"10","author":"Bressan","year":"2016","journal-title":"Front. Hum. Neurosci."},{"issue":"8","key":"10.1016\/j.neubiorev.2017.08.009_bib0040","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.autrev.2008.05.006","article-title":"Celiac disease: from gluten to autoimmunity","volume":"7","author":"Briani","year":"2008","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0045","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1093\/schbul\/sbp055","article-title":"Prevalence of celiac disease and gluten sensitivity in the United States clinical antipsychotic trials of intervention effectiveness study population","volume":"37","author":"Cascella","year":"2011","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0050","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1093\/schbul\/sbs064","article-title":"Increased prevalence of transglutaminase 6 antibodies in sera from schizophrenia patients","volume":"39","author":"Cascella","year":"2013","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0055","first-page":"32","article-title":"Mood disorders and non-celiac gluten sensitivity","volume":"63","author":"Casella","year":"2017","journal-title":"Minerva Gastroenterol. Dietol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0060","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1097\/MOG.0b013e32830edc1e","article-title":"Celiac disease","volume":"24","author":"Catassi","year":"2008","journal-title":"Curr. Opin. Gastroenterol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0065","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/j.1651-2227.1995.tb13725.x","article-title":"High prevalence of undiagnosed coeliae disease in 5280 Italian students screened by antigliadin antibodies","volume":"84","author":"Catassi","year":"1995","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4137\/IJTR.S2097","article-title":"Kynurenine pathway metabolites in humans: disease and healthy states","volume":"2","author":"Chen","year":"2009","journal-title":"Int. J. Tryptophan Res."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0075","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1710-1492-10-12","article-title":"The natural history of IgE mediated wheat allergy in children with dominant gastrointestinal symptoms","volume":"10","author":"Czaja-Bulsa","year":"2014","journal-title":"Allergy Asthma Clin. Immunol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0080","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/nrn2297","article-title":"From inflammation to sickness and depression: when the immune system subjugates the brain","volume":"9","author":"Dantzer","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0085","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1080\/10408398.2013.876959","article-title":"Omega 3 polyunsaturated fatty acids and the treatment of depression","volume":"57","author":"Deacon","year":"2017","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0090","series-title":"Coeliac Disease. Investigation of the Harmful Effects of Certain Types of Cereal on Patients with Coeliac Disease","author":"Dicke","year":"1950"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0095","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1399-5618.2011.00894.x","article-title":"Markers of gluten sensitivity and celiac disease in bipolar disorder","volume":"13","author":"Dickerson","year":"2011","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0100","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.psychres.2011.11.007","article-title":"Markers of gluten sensitivity in acute mania: a longitudinal study","volume":"196","author":"Dickerson","year":"2012","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0105","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1176\/ajp.130.6.685","article-title":"Relapsed schizophrenics: earlier discharge from the hospital after cereal-free, milk-free diet","volume":"130","author":"Dohan","year":"1973","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0110","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1192\/bjp.115.522.595","article-title":"Relapsed schizophrenics: more rapid improvement on a milk-and cereal-free diet","volume":"115","author":"Dohan","year":"1969","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0447.1966.tb01912.x","article-title":"Wartime changes in hospital admissions for schizophrenia","volume":"42","author":"Dohan","year":"1966","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0120","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.biopsych.2009.09.033","article-title":"A meta-analysis of cytokines in major depression","volume":"67","author":"Dowlati","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0125","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1136\/bmj.328.7437.438","article-title":"Coeliac disease and schizophrenia: population based case control study with linkage of Danish national registers","volume":"328","author":"Eaton","year":"2004","journal-title":"BMJ Br. Med. J."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0130","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1176\/appi.ajp.163.3.521","article-title":"Association of schizophrenia and autoimmune diseases: linkage of Danish national registers","volume":"163","author":"Eaton","year":"2006","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0135","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1111\/j.1399-5618.2010.00853.x","article-title":"Autoimmune diseases, bipolar disorder, and non-affective psychosis","volume":"12","author":"Eaton","year":"2010","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0140","doi-asserted-by":"crossref","first-page":"7110","DOI":"10.3748\/wjg.v21.i23.7110","article-title":"Diagnosis of gluten related disorders: celiac disease, wheat allergy and non-celiac gluten sensitivity","volume":"21","author":"Elli","year":"2015","journal-title":"World J. Gastroenterol WJG"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0145","doi-asserted-by":"crossref","first-page":"e0173015","DOI":"10.1371\/journal.pone.0173015","article-title":"A bidirectional relationship between depression and the autoimmune disorders\u2013new perspectives from the National Child Development Study","volume":"12","author":"Euesden","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0150","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1007\/s12519-016-0040-z","article-title":"Effect of gluten free diet on gastrointestinal and behavioral indices for children with autism spectrum disorders: a randomized clinical trial","volume":"12","author":"Ghalichi","year":"2016","journal-title":"World J. Pediatr."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0155","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1136\/gut.11.6.459","article-title":"A psychiatric study of patients with diseases of the small intestine","volume":"11","author":"Goldberg","year":"1970","journal-title":"Gut"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0160","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1007\/BF01566581","article-title":"Celiac syndrome in the case histories of five schizophrenics","volume":"35","author":"Graff","year":"1961","journal-title":"Psychiatr. Q."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0165","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1093\/brain\/awg050","article-title":"Gluten ataxia in perspective: epidemiology, genetic susceptibility and clinical characteristics","volume":"126","author":"Hadjivassiliou","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0170","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.it.2004.08.011","article-title":"The immunology of gluten sensitivity: beyond the gut","volume":"25","author":"Hadjivassiliou","year":"2004","journal-title":"Trends Immunol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0175","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1365-2036.2009.04053.x","article-title":"Systematic review: adherence to a gluten-free diet in adult patients with coeliac disease","volume":"30","author":"Hall","year":"2009","journal-title":"Aliment. Pharmacol Ther."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0180","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3109\/00365528209181038","article-title":"Psychic disturbances in adult coeliac disease: II. Psychological findings","volume":"17","author":"Hallert","year":"1982","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0185","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3109\/00365528209181039","article-title":"Psychic disturbances in adult coeliac disease: III. Reduced central monoamine metabolism and signs of depression","volume":"17","author":"Hallert","year":"1982","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0190","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S1059-1311(98)90008-5","article-title":"Epilepsy, cerebral calcifications and clinical or subclinical coeliac disease: course and follow up with gluten-free diet","volume":"7","author":"Hernandez","year":"1998","journal-title":"Seizure"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0195","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1136\/gut.32.12.1478","article-title":"Plasma precursor amino acids of central nervous system monoamines in children with coeliac disease","volume":"32","author":"Hernanz","year":"1991","journal-title":"Gut"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0200","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.schres.2012.06.011","article-title":"A gluten-free diet in people with schizophrenia and anti-tissue transglutaminase or anti-gliadin antibodies","volume":"140","author":"Jackson","year":"2012","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0205","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s11126-011-9186-y","article-title":"Neurologic and psychiatric manifestations of celiac disease and gluten sensitivity","volume":"83","author":"Jackson","year":"2012","journal-title":"Psychiatr. Q."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0210","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/ajmg.b.30605","article-title":"Is MYO9 B the missing link between schizophrenia and celiac disease?","volume":"147","author":"Jungerius","year":"2008","journal-title":"Am. J. Med. Genet. Part B Neuropsychiatr. Genet."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0215","series-title":"Aetiology: Severe Infection and Autoimmune Disease are Associated with Increased Risk of Mood Disorders","author":"Kayser","year":"2014"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0220","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.schres.2013.12.001","article-title":"Biomarkers of gluten sensitivity in patients with non-affective psychosis: a meta-analysis","volume":"152","author":"Lachance","year":"2014","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0225","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/ajmg.b.31213","article-title":"No association observed between schizophrenia and non-HLA coeliac disease genes: integration with the initial MYO9 B association with coeliac disease","volume":"156","author":"Law","year":"2011","journal-title":"Am. J. Med. Genet. Part B Neuropsychiatr. Genet."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0230","doi-asserted-by":"crossref","first-page":"h4347","DOI":"10.1136\/bmj.h4347","article-title":"Celiac disease and non-celiac gluten sensitivity","volume":"351","author":"Lebwohl","year":"2015","journal-title":"BMJ"},{"issue":"9","key":"10.1016\/j.neubiorev.2017.08.009_bib0235","first-page":"14916","article-title":"Association between the MYO9 B polymorphisms and celiac disease risk: a meta-analysis","volume":"8","author":"Liao","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0240","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1111\/j.1365-2036.2007.03502.x","article-title":"Increasing prevalence of coeliac disease over time","volume":"26","author":"Lohi","year":"2007","journal-title":"Aliment. Pharmacol. Ther."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0245","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1034\/j.1399-0039.2003.00017.x","article-title":"HLA in coeliac disease: unravelling the complex genetics of a complex disorder","volume":"61","author":"Louka","year":"2003","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0250","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/00365520600863472","article-title":"Coeliac disease and risk of schizophrenia and other psychosis: a general population cohort study","volume":"42","author":"Ludvigsson","year":"2007","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0255","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jad.2006.08.032","article-title":"Coeliac disease and risk of mood disorders\u2014a general population-based cohort study","volume":"99","author":"Ludvigsson","year":"2007","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0260","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3109\/07853890108995958","article-title":"Coeliac disease in patients with cerebellar ataxia of unknown origin","volume":"33","author":"Luostarinen","year":"2001","journal-title":"Ann. Med."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2017.01.001","article-title":"Polyunsaturated fatty acids and recurrent mood disorders: phenomenology, mechanisms, and clinical application","author":"Messamore","year":"2017","journal-title":"Prog. Lipid Res"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0270","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.socscimed.2014.01.009","article-title":"\u2018But we\u2019re not hypochondriacs\u2019: the changing shape of gluten-free dieting and the contested illness experience","volume":"105","author":"Moore","year":"2014","journal-title":"Soc. Sci. Med."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0275","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0065-2423(07)44002-1","article-title":"Deamidated gliadin peptides as targets for celiac disease-specific antibodies","volume":"44","author":"Mothes","year":"2007","journal-title":"Adv. Clin. Chem."},{"issue":"5","key":"10.1016\/j.neubiorev.2017.08.009_bib0280","first-page":"627","article-title":"Lack of effect of a gluten-free diet on neuroleptic blood levels in schizophrenic patients","volume":"17","author":"Osborne","year":"1982","journal-title":"Biol. Psychiatry"},{"issue":"11","key":"10.1016\/j.neubiorev.2017.08.009_bib0285","article-title":"Wheat gluten challenge in schizophrenic patients","volume":"138","author":"Potkin","year":"1981","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0290","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.3109\/00365521.2014.928903","article-title":"Myosin IXb variants and their pivotal role in maintaining the intestinal barrier: a study in Crohn\u2019s disease","volume":"49","author":"Prager","year":"2014","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0295","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1471-244X-5-14","article-title":"Gluten-free diet may alleviate depressive and behavioural symptoms in adolescents with coeliac disease: a prospective follow-up case-series study","volume":"5","author":"Pynn\u00f6nen","year":"2005","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0300","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.jpsychires.2015.05.007","article-title":"Kynurenine pathway dysfunction in the pathophysiology and treatment of depression: evidences from animal and human studies","volume":"68","author":"R\u00e9us","year":"2015","journal-title":"J. Psychiatr. Res."},{"issue":"11","key":"10.1016\/j.neubiorev.2017.08.009_bib0305","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1176\/ajp.135.11.1417","article-title":"Another look at gluten in schizophrenia","volume":"135","author":"Rice","year":"1978","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0310","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.neubiorev.2014.02.004","article-title":"The theory of bipolar disorder as an illness of accelerated aging: implications for clinical care and research","volume":"42","author":"Rizzo","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0315","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jad.2015.08.058","article-title":"Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: evidence, pathophysiology and treatment implications","volume":"188","author":"Rosenblat","year":"2015","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0320","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1053\/j.gastro.2009.03.059","article-title":"Increased prevalence and mortality in undiagnosed celiac disease","volume":"137","author":"Rubio-Tapia","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0325","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.schres.2009.08.009","article-title":"Novel immune response to gluten in individuals with schizophrenia","volume":"118","author":"Samaroo","year":"2010","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0330","series-title":"Is Gluten the Great Etiopathogenic Agent of Disease in the XXI Century?","author":"San Mauro","year":"2014"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0335","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1741-7015-9-23","article-title":"Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity","volume":"9","author":"Sapone","year":"2011","journal-title":"BMC Med."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0340","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1741-7015-10-13","article-title":"Spectrum of gluten-related disorders: consensus on new nomenclature and classification","volume":"10","author":"Sapone","year":"2012","journal-title":"BMC Med."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0345","first-page":"240","article-title":"A retrospective chart review evaluating the association of psychological disorders and Vitamin D deficiency with celiac disease","volume":"62","author":"Sarela","year":"2016","journal-title":"Minerva Gastroenterol. Dietol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0350","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.3899\/jrheum.141361","article-title":"Risk of psychiatric disorders following primary Sj\u00f6gren syndrome: a nationwide population-based retrospective cohort study","volume":"42","author":"Shen","year":"2015","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0355","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1126\/science.1246624","article-title":"Wheat gluten as a pathogenic factor in schizophrenia","volume":"191","author":"Singh","year":"1976","journal-title":"Science"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0360","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1600-0447.2011.01795.x","article-title":"Meta-analysis on anxiety and depression in adult celiac disease","volume":"125","author":"Smith","year":"2012","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0365","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1001\/archpsyc.1982.04290030055010","article-title":"Effects of gluten on schizophrenics","volume":"39","author":"Storms","year":"1982","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0370","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/ng1195-287","article-title":"A potential vulnerability locus for schizophrenia on chromosome 6p24\u201322: evidence for genetic heterogeneity","volume":"11","author":"Straub","year":"1995","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0375","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1271\/bbb.70708","article-title":"Analysis of food allergen structures and development of foods for allergic patients","volume":"72","author":"Tanabe","year":"2008","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0380","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.autrev.2014.01.043","article-title":"Diagnosis and classification of celiac disease and gluten sensitivity","volume":"13","author":"Tonutti","year":"2014","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0385","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1007\/s00122-010-1408-4","article-title":"Presence of celiac disease epitopes in modern and old hexaploid wheat varieties: wheat breeding may have contributed to increased prevalence of celiac disease","volume":"121","author":"Van den Broeck","year":"2010","journal-title":"Theor. Appl. Genet."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0390","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1038\/ajg.2009.188","article-title":"Between celiac disease and irritable bowel syndrome: the no man\u2019s land of gluten sensitivity","volume":"104","author":"Verdu","year":"2009","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0395","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1097\/MCG.0b013e31827874e3","article-title":"Biomarkers for diagnosis and monitoring of celiac disease","volume":"47","author":"Vives-Pi","year":"2013","journal-title":"J. Clin. Gastroenterol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0400","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1192\/bjp.148.4.447","article-title":"A double-blind gluten-free\/gluten-load controlled trial in a secure ward population","volume":"148","author":"Vlissides","year":"1986","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0405","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/17474124.2017.1260003","article-title":"Non-coeliac gluten\/wheat sensitivity: advances in knowledge and relevant questions","volume":"11","author":"Volta","year":"2017","journal-title":"Expert Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0410","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1365-2036.2006.02720.x","article-title":"Risk of schizophrenia in people with coeliac disease, ulcerative colitis and Crohn\u2019s disease: a general population-based study","volume":"23","author":"West","year":"2006","journal-title":"Aliment. Pharmacol. Ther."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0415","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.neubiorev.2016.11.010","article-title":"Selfish brain and selfish immune system interplay: a theoretical framework for metabolic comorbidities of mood disorders","volume":"72","author":"Yamagata","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neubiorev.2017.08.009_bib0420","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/ng1196-329","article-title":"An autosomal screen for genes that predispose to celiac disease in the western counties of Ireland","volume":"14","author":"Zhong","year":"1996","journal-title":"Nat. Genet."}],"container-title":["Neuroscience & Biobehavioral Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763417304360?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763417304360?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T22:25:30Z","timestamp":1530138330000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0149763417304360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":84,"alternative-id":["S0149763417304360"],"URL":"https:\/\/doi.org\/10.1016\/j.neubiorev.2017.08.009","relation":{},"ISSN":["0149-7634"],"issn-type":[{"value":"0149-7634","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gluten related illnesses and severe mental disorders: a comprehensive review","name":"articletitle","label":"Article Title"},{"value":"Neuroscience & Biobehavioral Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neubiorev.2017.08.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}