{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:57:02Z","timestamp":1790801822552,"version":"4.1.0"},"reference-count":195,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Vanderbilt University Undergraduate Immersion Program"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience & Biobehavioral Reviews"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.neubiorev.2020.05.017","type":"journal-article","created":{"date-parts":[[2020,5,30]],"date-time":"2020-05-30T11:11:08Z","timestamp":1590837068000},"page":"199-219","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"special_numbering":"C","title":["Seasonal effects on bipolar disorder: A closer look"],"prefix":"10.1016","volume":"115","author":[{"given":"Sandra J.","family":"Rosenthal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Travis","family":"Josephs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oleg","family":"Kovtun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"McCarty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neubiorev.2020.05.017_bib0005","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jad.2015.07.017","article-title":"The bipolarity of light and dark: a review on bipolar disorder and circadian cycles","volume":"185","author":"Abreu","year":"2015","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0010","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1080\/07420528.2017.1374286","article-title":"The influence of sunlight exposure on hospitalization in emergency psychiatry","volume":"34","author":"Aguglia","year":"2017","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0015","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1590\/1516-4446-2016-2144","article-title":"Bipolar disorders: is there an influence of seasonality or photoperiod? Rev","volume":"40","author":"Aguglia","year":"2018","journal-title":"Rev. Bras. Psiquiatr."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0020","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.3390\/ijerph16071140","article-title":"Maximum temperature and solar radiation as predictors of bipolar patient admission in an emergency psychiatric ward","volume":"16","author":"Aguglia","year":"2019","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0025","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.neubiorev.2013.11.005","article-title":"Biological and psychological markers of stress in humans: focus on the Trier Social Stress Test","volume":"38","author":"Allen","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0030","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s11920-017-0772-z","article-title":"Circadian rhythm dysregulation in bipolar spectrum disorders","volume":"19","author":"Alloy","year":"2017","journal-title":"Curr. Psychiatry Rep."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0035","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2013"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.conb.2016.12.010","article-title":"Sleep loss and structural plasticity","volume":"44","author":"Areal","year":"2017","journal-title":"Curr. Opinion Neurobiol."},{"issue":"2","key":"10.1016\/j.neubiorev.2020.05.017_bib0045","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1080\/15402002.2014.974179","article-title":"Lifetime characteristics of evening-preference and irregular bed-rise time are associated with lifetime seasonal variation of mood and behavior: comparison between individuals with bipolar disorder and healthy controls","volume":"14","author":"Baek","year":"2016","journal-title":"Behav. Sleep Med."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0050","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1399-5618.2004.00166.x","article-title":"Dark therapy for mania: a pilot study","volume":"7","author":"Barbini","year":"2005","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0055","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3109\/15622970109027495","article-title":"Thyroid hormone, neural tissue and mood modulation","volume":"2","author":"Bauer","year":"2001","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0060","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jad.2008.11.013","article-title":"Relationship among latitude, climate, season and self-reported mood in bipolar disorder","volume":"116","author":"Bauer","year":"2009","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0065","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1399-5618.2012.01025.x","article-title":"Impact of sunlight on the age of onset of bipolar disorder","volume":"14","author":"Bauer","year":"2012","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0070","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jad.2014.05.032","article-title":"Relationship between sunlight and the age of onset of bipolar disorder: an international multisite study","volume":"167","author":"Bauer","year":"2014","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpsychires.2019.03.001","article-title":"Association between solar insolation and a history of suicide attempts in bipolar I disorder","volume":"113","author":"Bauer","year":"2019","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0080","doi-asserted-by":"crossref","first-page":"e1017","DOI":"10.1038\/tp.2016.262","article-title":"Timing of light exposure affects mood and brain circuits","volume":"7","author":"Bedrosian","year":"2017","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0085","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1056\/NEJMra035354","article-title":"Bipolar disorder","volume":"351","author":"Belmaker","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0090","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.psyneuen.2015.10.014","article-title":"The HPA axis in bipolar disorder: systematic review and meta-analysis","volume":"63","author":"Belvederi Murri","year":"2016","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0095","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.jad.2017.05.008","article-title":"Night sleep influences white matter microstructure in bipolar depression","volume":"218","author":"Benedetti","year":"2017","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0100","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000328947","article-title":"Sleep deprivation in mood disorders","volume":"64","author":"Benedetti","year":"2011","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0105","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.coemr.2017.12.001","article-title":"New insights on thyroid hormone and the brain","volume":"2","author":"Bernal","year":"2018","journal-title":"Curr. Opin. Endocr. Metab. Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2018.09.054","article-title":"Sleep and circadian rhythms as possible trait markers of suicide attempt in bipolar disorders: an actigraphy study","volume":"244","author":"Bernard","year":"2019","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0115","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.3109\/07420528.2013.798330","article-title":"Chronotypes of bipolar patients in remission: validation of the French version of the circadian type inventory in the FACE-BD sample","volume":"30","author":"Boudebesse","year":"2013","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0120","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1017\/S0033291717000186","article-title":"Sleep and circadian rhythm disturbance in bipolar disorder","volume":"47","author":"Bradley","year":"2017","journal-title":"Psychol. Med. (Paris)"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0125","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-3-642-25950-0_1","article-title":"Molecular components of the mammalian circadian clock","volume":"217","author":"Buhr","year":"2013","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0130","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.comppsych.2016.03.005","article-title":"Differential melatonin alterations in cerebrospinal fluid and serum of patients with major depressive disorder and bipolar disorder","volume":"68","author":"Bumb","year":"2016","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0135","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1152\/physrev.1929.9.3.399","article-title":"Organization for physiological homeostasis","volume":"9","author":"Cannon","year":"1929","journal-title":"Physiol. Rev."},{"issue":"5","key":"10.1016\/j.neubiorev.2020.05.017_bib0140","first-page":"411","article-title":"Circadian secretion of cortisol in bipolar disorder","volume":"26","author":"Cervantes","year":"2001","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0145","doi-asserted-by":"crossref","DOI":"10.4061\/2011\/306367","article-title":"Thyroid functions and bipolar affective disorder","volume":"2011","author":"Chakrabarti","year":"2011","journal-title":"J. Thyroid Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cell.2020.01.012","article-title":"Identifying and interpreting apparent Neanderthal ancestry in African individuals","volume":"180","author":"Chen","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0155","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0165-0327(02)00009-5","article-title":"The stability of the Seasonal Pattern Assessment Questionnaire score index over time and the validity compared to classi\ufb01cation according to DSM-III-R","volume":"74","author":"Christensen","year":"2003","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0160","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1056\/NEJMp1500523","article-title":"A new initiative on precision medicine","volume":"372","author":"Collins","year":"2015","journal-title":"New Engl. J. Med."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0165","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0165-1781(99)00036-0","article-title":"Rate of switch from depression into mania after therapeutic sleep deprivation in bipolar depression","volume":"86","author":"Colombo","year":"1999","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0170","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0165-1781(00)00164-5","article-title":"Total sleep deprivation combined with lithium and light therapy in the treatment of bipolar depression: replication of main e\ufb00 ;ects and interaction","volume":"95","author":"Colombo","year":"2000","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0175","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.yfrne.2014.11.002","article-title":"The suprachiasmatic nuclei as a seasonal clock","volume":"37","author":"Coomans","year":"2015","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0180","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1007\/s11920-009-0074-1","article-title":"Melatonin, circadian rhythms, and the clock genes in bipolar disorder","volume":"11","author":"Dallaspezia","year":"2009","journal-title":"Curr. Psychiat. Rep."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0185","first-page":"113","article-title":"Regulation of ACTH secretion: variations on a theme of B. Recent Prog","volume":"43","author":"Dallman","year":"1987","journal-title":"Horm. Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0190","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.smrv.2016.05.003","article-title":"Actigraphic features of bipolar disorder: a systematic review and meta-analysis","volume":"33","author":"De Crescenzo","year":"2017","journal-title":"Sleep Med. Rev."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0195","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nrn1683","article-title":"Stress and the brain: from adaptation to disease","volume":"6","author":"de Kloet","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0200","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1146\/annurev-physiol-021909-135821","article-title":"The mammalian circadian timing system: organization and coordination of central and peripheral clocks","volume":"72","author":"Dibner","year":"2010","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0205","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3389\/fpsyt.2020.00095","article-title":"Sensitivity to climate and weather changes in euthymic bipolar subjects: association with suicide attempts","volume":"11","author":"DiNicola","year":"2020","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0210","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1152\/physrev.00013.2010","article-title":"Intrinsically photosensitive retinal ganglion cells","volume":"90","author":"Do","year":"2010","journal-title":"Physiol. Rev."},{"issue":"8","key":"10.1016\/j.neubiorev.2020.05.017_bib0215","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1111\/j.1399-5618.2007.00421.x","article-title":"The early manifestations of bipolar disorder: a longitudinal prospective study of the offspring of bipolar parents","volume":"9","author":"Duffy","year":"2007","journal-title":"Bipolar Disord."},{"issue":"1","key":"10.1016\/j.neubiorev.2020.05.017_bib0220","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0306-4530(02)00135-X","article-title":"High levels of cortisol among adolescent offspring of parents with bipolar disorder: a pilot study","volume":"29","author":"Ellenbogen","year":"2004","journal-title":"Psychoneuroendocrinology"},{"issue":"10","key":"10.1016\/j.neubiorev.2020.05.017_bib0225","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.psyneuen.2006.08.004","article-title":"Daytime cortisol and stress reactivity in the offspring of parents with bipolar disorder","volume":"31","author":"Ellenbogen","year":"2006","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0230","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00127-015-1091-5","article-title":"Epidemiology and burden of bipolar disorder in Africa: a systematic review of data from Africa","volume":"51","author":"Esen","year":"2016","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"issue":"18","key":"10.1016\/j.neubiorev.2020.05.017_bib0235","doi-asserted-by":"crossref","first-page":"4030","DOI":"10.1093\/hmg\/dds227","article-title":"Genetic and functional abnormalities of the melatonin biosynthesis pathway in patients with bipolar disorder","volume":"21","author":"Etain","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0240","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.3109\/07420528.2015.1078346","article-title":"Clinical correlates of chronotypes in young persons with mental disorders","volume":"32","author":"Fares","year":"2015","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0245","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.jad.2018.09.073","article-title":"Seasonality in bipolar disorder: effect of age and sex","volume":"243","author":"Fellinger","year":"2019","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0250","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/s12916-017-0849-x","article-title":"The new field of \u2018precision psychiatry\u2019","volume":"15","author":"Fernandes","year":"2017","journal-title":"BMC Med."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0255","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.clim.2017.04.004","article-title":"The role of IL\u20106 and STAT in sleep and neuroinflammation","volume":"180","author":"Fernandes","year":"2017","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0260","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1111\/bdi.12423","article-title":"The prevalence and burden of bipolar disorder: findings from the Global Burden of Disease Study 2013","volume":"18","author":"Ferrari","year":"2016","journal-title":"Bipolar Disord."},{"issue":"1","key":"10.1016\/j.neubiorev.2020.05.017_bib0265","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jad.2007.04.003","article-title":"Preschool bipolar disorder: brazilian children case reports","volume":"104","author":"Ferreira Maia","year":"2007","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0270","doi-asserted-by":"crossref","first-page":"E2751","DOI":"10.1073\/pnas.1407935111","article-title":"Dopamine transporters govern diurnal variation in extracellular dopamine tone","volume":"111","author":"Ferris","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"4","key":"10.1016\/j.neubiorev.2020.05.017_bib0275","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1034\/j.1399-5618.2001.30405.x","article-title":"Rapid, continuous cycling and psychiatric co-morbidity in pediatric bipolar I disorder","volume":"3","author":"Findling","year":"2001","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0280","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/j.1399-5618.2008.00654.x","article-title":"Polarity at illness onset in bipolar I disorder and clinical course of illness","volume":"11","author":"Forty","year":"2009","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0285","series-title":"Treating Bipolar Disorder: A Clinician\u2019s Guide to Interpersonal and Social Rhythm Therapy","author":"Frank","year":"2007"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0290","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0006-3223(00)00969-0","article-title":"Interpersonal and social rhythm therapy: managing the chaos of bipolar disorder","volume":"48","author":"Frank","year":"2000","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0295","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1111\/j.1600-0447.2005.00701.x","article-title":"Seasonal changes in clinical status in bipolar disorder: a prospective study in 1000 STEP-BD patients","volume":"113","author":"Friedman","year":"2006","journal-title":"Acta Psychiatr. Scand."},{"issue":"1","key":"10.1016\/j.neubiorev.2020.05.017_bib0300","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.schres.2006.11.020","article-title":"Plasma cortisol-dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder","volume":"90","author":"Gallagher","year":"2007","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0305","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.biopsych.2018.09.006","article-title":"Clock genes and light signaling alterations in bipolar disorder: when the biological clock is off","volume":"84","author":"Geoffroy","year":"2018","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0310","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jad.2014.07.002","article-title":"Seasonality and bipolar disorder: a systematic review, from admission rates to seasonality of symptoms","volume":"168","author":"Geoffroy","year":"2014","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0315","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/acps.12367","article-title":"Sleep in patients with remitted bipolar disorder: a meta-analysis of actigraphy studies","volume":"131","author":"Geoffroy","year":"2015","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0320","doi-asserted-by":"crossref","first-page":"3352","DOI":"10.2174\/1381612821666150619093448","article-title":"Melatonin and melatonin agonists as adjunctive treatments in bipolar disorders","volume":"21","author":"Geoffroy","year":"2015","journal-title":"Curr. Pharmaceut. Design"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0325","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1080\/15622975.2017.1282174","article-title":"Lithium response in bipolar disorders and core clock genes expression","volume":"19","author":"Geoffroy","year":"2017","journal-title":"World J. Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.neubiorev.2020.05.017_bib0330","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s11325-009-0301-3","article-title":"Circadian preference in bipolar disorder","volume":"14","author":"Giglio","year":"2010","journal-title":"Sleep Breath."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0335","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.psyneuen.2014.07.013","article-title":"Morning cortisol levels in schizophrenia and bipolar disorder: a meta-analysis","volume":"49","author":"Girshkin","year":"2014","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0340","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2147\/NSS.S85754","article-title":"The role of sleep in bipolar disorder","volume":"8","author":"Gold","year":"2016","journal-title":"Nat. Sci. Sleep"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0345","series-title":"Manic-Depressive Illness: Bipolar Disorders and Recurrent Depression","author":"Goodwin","year":"2007"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0350","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1176\/appi.ajp.160.4.636","article-title":"The endophenotype concept in psychiatry: etymology and strategic intentions","volume":"160","author":"Gottesman","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0355","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/bdi.12847","article-title":"The chronotherapeutic treatment of bipolar disorders: a systematic review and practice recommendations from the ISBD task force on chronotherapy and chronobiology","volume":"21","author":"Gottlieb","year":"2019","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0360","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1126\/science.1188021","article-title":"A draft sequence of the Neanderthal genome","volume":"328","author":"Green","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0365","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.cub.2015.03.050","article-title":"Photoperiod programs dorsal raphe serotonergic neurons and affective behavior","volume":"25","author":"Green","year":"2015","journal-title":"Curr. Biol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0370","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1192\/bjp.188.5.465","article-title":"Lifetime and 12-month prevalence of mental disorders in the Nigerian Survey of Mental Health and Well-Being","volume":"188","author":"Gureje","year":"2006","journal-title":"Brit. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0375","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/j.psyneuen.2006.04.004","article-title":"The heritability of melatonin secretion and sensitivity to bright nocturnal light in twins","volume":"31","author":"Hallam","year":"2006","journal-title":"Psychoneuroendocrinology"},{"issue":"5","key":"10.1016\/j.neubiorev.2020.05.017_bib0380","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1111\/j.1601-5215.2009.00416.x","article-title":"Abnormal dose-response melatonin suppression by light in bipolar type I patients compared with healthy adult subjects","volume":"21","author":"Hallam","year":"2009","journal-title":"Acta Neuropsychiatr."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0385","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1176\/appi.ajp.2008.08010098","article-title":"Sleep and circadian rhythms in bipolar disorder: seeking synchrony, harmony, and regulation","volume":"165","author":"Harvey","year":"2008","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0390","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1146\/annurev-clinpsy-032210-104550","article-title":"Sleep and circadian functioning: critical mechanisms in the mood disorders?","volume":"7","author":"Harvey","year":"2011","journal-title":"Annu. Rev. Clin. Psychol."},{"issue":"1","key":"10.1016\/j.neubiorev.2020.05.017_bib0395","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1176\/appi.ajp.162.1.50","article-title":"Sleep-related functioning in euthymic patients with bipolar disorder, patients with insomnia, and subjects without sleep problems","volume":"162","author":"Harvey","year":"2005","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0400","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.biopsych.2005.11.006","article-title":"Toward constructing an endophenotype strategy for bipolar disorders","volume":"60","author":"Hasler","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0405","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.molmed.2010.07.005","article-title":"The emerging roles of melanopsin in behavioral adaptation to light","volume":"16","author":"Hatori","year":"2010","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0410","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.03357","article-title":"Lhx1 maintains synchrony among circadian oscillator neurons of the SCN","volume":"3","author":"Hatori","year":"2014","journal-title":"Elife"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0415","doi-asserted-by":"crossref","DOI":"10.1098\/rspb.2013.0016","article-title":"Annual rhythms that underlie phenology: biological time-keeping meets environmental change","volume":"280","author":"Helm","year":"2013","journal-title":"Proc. R. Soc. B."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0420","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/s41398-019-0632-1","article-title":"Vulnerability to bipolar disorder is linked to sleep and sleepiness","volume":"9","author":"Hensch","year":"2019","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0425","first-page":"226","article-title":"Group interpersonal and social rhythm therapy for bipolar depression","volume":"49","author":"Hoberg","year":"2013","journal-title":"Perspect. Psychiatr. Care"},{"issue":"8","key":"10.1016\/j.neubiorev.2020.05.017_bib0430","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1111\/j.1399-5618.2007.00463.x","article-title":"Prevalence of the child behavior checklist-pediatric bipolar disorder phenotype in a German general population sample","volume":"9","author":"Holtmann","year":"2007","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0435","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.bbi.2017.11.009","article-title":"The ying\/yang of inflammatory status: blood\u2010brain barrier regulation during sleep","volume":"69","author":"Hurtado\u2010Alvarado","year":"2018","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0440","doi-asserted-by":"crossref","first-page":"20130433","DOI":"10.1098\/rspb.2013.0433","article-title":"Latitudinal clines: an evolutionary view on biological rhythms","volume":"280","author":"Hut","year":"2013","journal-title":"Proc. R. Soc. B."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0445","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1038\/s41574-019-0237-z","article-title":"Interconnection between circadian clocks and thyroid function","volume":"15","author":"Ikegami","year":"2019","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0450","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1192\/bjp.113.501.895","article-title":"A manic depressive psychotic with a persistent forty-eight hour cycle","volume":"113","author":"Jenner","year":"1967","journal-title":"Brit. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0455","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1399-5618.2005.00187.x","article-title":"Actigraphic assessment of circadian activity and sleep patterns in bipolar disorder","volume":"7","author":"Jones","year":"2005","journal-title":"Bipolar Disord."},{"issue":"3","key":"10.1016\/j.neubiorev.2020.05.017_bib0460","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jad.2011.11.027","article-title":"Associations between suicide attempts and elevated bedtime salivary cortisol levels in bipolar disorder","volume":"136","author":"Kamali","year":"2012","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0465","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4088\/JCP.v67n0204","article-title":"The relationship between depression and sleep disturbances: a Japanese nationwide population survey","volume":"67","author":"Kaneita","year":"2006","journal-title":"J. Clin. Psychiatry"},{"issue":"2","key":"10.1016\/j.neubiorev.2020.05.017_bib0470","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0165-1781(96)02910-1","article-title":"Nocturnal melatonin and 24-hour 6-sulphatoxymelatonin levels in various phases of bipolar affective disorder","volume":"63","author":"Kennedy","year":"1996","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0475","doi-asserted-by":"crossref","first-page":"R271","DOI":"10.1093\/hmg\/ddl207","article-title":"Molecular components of the mammalian circadian clock","volume":"15","author":"Ko","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0480","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.cplett.2018.06.019","article-title":"Single quantum dot tracking illuminates neuroscience at the nanoscale","volume":"706","author":"Kovtun","year":"2018","journal-title":"Chem. Phys. Lett."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0485","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.neuroscience.2015.04.053","article-title":"Sleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive function","volume":"309","author":"Kreutzmann","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0490","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3389\/fnint.2018.00010","article-title":"The times of our lives: interactions among different biological periodicities","volume":"12","author":"Laje","year":"2018","journal-title":"Front. Integr. Neurosci."},{"issue":"2","key":"10.1016\/j.neubiorev.2020.05.017_bib0495","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0165-1781(90)90066-E","article-title":"Melatonin suppression in bipolar and unipolar mood disorders","volume":"33","author":"Lam","year":"1990","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0500","doi-asserted-by":"crossref","first-page":"15172","DOI":"10.1073\/pnas.0806717105","article-title":"Physiological significance of a peripheral tissue circadian clock","volume":"105","author":"Lamia","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0505","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1176\/ajp.142.6.725","article-title":"Supersensitivity to light: possible trait marker for manic-depressive illness","volume":"142","author":"Lewy","year":"1985","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0510","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s11920-009-0070-5","article-title":"Circadian misalignment in mood disturbances","volume":"11","author":"Lewy","year":"2009","journal-title":"Curr. Psychiatry Rep."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0515","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0140-6736(81)91697-4","article-title":"Manic-depressive patients may be supersensitive to light","volume":"1","author":"Lewy","year":"1981","journal-title":"Lancet"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0520","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1749-6632.1985.tb11815.x","article-title":"Immediate and delayed effects of bright light on human melatonin production: shifting \u201cdawn\u201d and \u201cdusk\u201d shifts the dim light melatonin onset (DLMO)","volume":"453","author":"Lewy","year":"1985","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0525","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.egypro.2015.07.399","article-title":"An analysis of global, direct and diffuse solar radiation","volume":"75","author":"Li","year":"2015","journal-title":"Energy Procedia"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0530","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1146\/annurev-pharmtox-010814-124742","article-title":"MT1 and MT2 melatonin receptors: a therapeutic perspective","volume":"56","author":"Liu","year":"2016","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0535","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.jad.2017.12.106","article-title":"Seasonality of depressive symptoms in women but not in men: a cross-sectional study in the UK Biobank cohort","volume":"229","author":"Lyall","year":"2018","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0540","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1081\/CBI-200062413","article-title":"Circadian phase variation in bipolar I disorder","volume":"22","author":"Mansour","year":"2005","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0545","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1080\/07420528.2018.1487975","article-title":"The neurobiology of adaptation to seasons: relevance and correlations in bipolar disorders","volume":"35","author":"Maruani","year":"2018","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0550","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.neuroimage.2015.03.007","article-title":"Diurnal and seasonal variation of the brain serotonin system in healthy male subjects","volume":"112","author":"Matheson","year":"2015","journal-title":"Neuroimage"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0555","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1046\/j.1365-2869.2000.00186.x","article-title":"Subjective measure of insomnia and quality of life in depressed inpatients","volume":"9","author":"McCall","year":"2000","journal-title":"J. Sleep Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0560","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/YPG.0000000000000215","article-title":"Missing a beat: assessment of circadian rhythm abnormalities in bipolar disorder in the genomic era","volume":"29","author":"McCarthy","year":"2019","journal-title":"Psychiatr. Genet."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0565","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.neuropharm.2015.10.017","article-title":"Calcium channel genes associated with bipolar disorder modulate lithium\u2019s amplification of circadian rhythms","volume":"101","author":"McCarthy","year":"2016","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0570","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1016\/j.euroneuro.2016.05.003","article-title":"Disinhibition of the extracellular-signal-regulated kinase restores the amplification of circadian rhythms by lithium in cells from bipolar disorder patients","volume":"26","author":"McCarthy","year":"2016","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0575","series-title":"Stress and Mental Disorders: Insights From Animal Models","author":"McCarty","year":"2020"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0580","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1001\/archpsyc.60.5.497","article-title":"The heritability of bipolar affective disorder and the genetic relationship to unipolar depression","volume":"60","author":"McGuffin","year":"2003","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0585","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.ygcen.2007.01.018","article-title":"Processing of daily and seasonal light information in the mammalian circadian clock","volume":"152","author":"Meijer","year":"2007","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0590","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jpsychires.2016.09.005","article-title":"Sleep and circadian alterations in people at risk for bipolar disorder: a systematic review","volume":"83","author":"Melo","year":"2016","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0595","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.smrv.2016.06.007","article-title":"Chronotype and circadian rhythm in bipolar disorder: a systematic review","volume":"34","author":"Melo","year":"2017","journal-title":"Sleep Med. Rev."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0600","doi-asserted-by":"crossref","DOI":"10.1177\/0748730419881922","article-title":"Seasonal variations of locomotor activity rhythms in melatonin-proficient and -deficient mice under semi-natural outdoor conditions","author":"Metzger","year":"2020","journal-title":"J. Biol. Rhythms in press."},{"issue":"2","key":"10.1016\/j.neubiorev.2020.05.017_bib0605","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0165-0327(03)00055-7","article-title":"The sleep of remitted bipolar outpatients: a controlled naturalistic study using actigraphy","volume":"80","author":"Millar","year":"2004","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0610","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1146\/annurev-neuro-060909-153128","article-title":"Central and peripheral circadian clocks in mammals","volume":"35","author":"Mohawk","year":"2012","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0615","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1192\/bjp.115.525.923","article-title":"Circadian rhythms of water and electrolyte excretion in manic-depressive psychosis","volume":"115","author":"Moody","year":"1969","journal-title":"Brit. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0620","first-page":"R735","article-title":"Physiology of the circadian timing system: predictive versus reactive homeostasis","volume":"250","author":"Moore-Ede","year":"1986","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0625","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3109\/07420528.2016.1151026","article-title":"Lithium and bipolar disorder: impact from molecular to behavioural circadian rhythms","volume":"33","author":"Moreira","year":"2016","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0630","doi-asserted-by":"crossref","first-page":"329","DOI":"10.3109\/08039488.2015.1112832","article-title":"Eveningness and poor sleep quality independently contribute to self-reported depression severity in psychiatric inpatients with affective disorder","volume":"70","author":"Muller","year":"2016","journal-title":"Nord. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0635","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0140-6736(02)07450-0","article-title":"Bipolar disorder","volume":"358","author":"M\u00fcller-Oerlinghausen","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0640","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/j.1399-5618.2011.00959.x","article-title":"Do symptoms of bipolar disorder exhibit seasonal variation? A multisite prospective investigation","volume":"13","author":"Murray","year":"2011","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0645","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/cpp.710","article-title":"Self-management strategies used by \u2018high functioning\u2019 individuals with bipolar disorder: from research to clinical practice","volume":"18","author":"Murray","year":"2011","journal-title":"Clin. Psychol. Psychother."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0650","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.steroids.2016.05.013","article-title":"Further evidence for a membrane receptor that binds glucocorticoids in the rodent hypothalamus","volume":"114","author":"Nahar","year":"2016","journal-title":"Steroids"},{"issue":"3","key":"10.1016\/j.neubiorev.2020.05.017_bib0655","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/S0893-133X(99)00018-4","article-title":"Melatonin sensitivity to dim white light in affective disorders","volume":"21","author":"Nathan","year":"1999","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0660","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.smrv.2014.06.006","article-title":"Sleep-wake disturbance in interepisode bipolar disorder and high-risk individuals: a systematic review and meta-analysis","volume":"20","author":"Ng","year":"2015","journal-title":"Sleep Med. Rev."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0665","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/bdi.12270","article-title":"The circadian system of patients with bipolar disorder differs in episodes of mania and depression","volume":"17","author":"Novakova","year":"2015","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0670","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0893-133X(88)90020-6","article-title":"Supersensitivity to melatonin suppression by light in young people at high risk for affective disorder: a preliminary report","volume":"1","author":"Nurnberger","year":"1988","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0675","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1001\/archpsyc.57.6.572","article-title":"Melatonin suppression by light in euthymic bipolar and unipolar patients","volume":"57","author":"Nurnberger","year":"2000","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0680","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.psychres.2010.10.033","article-title":"An admixture analysis of the age at index episodes in bipolar disorder","volume":"188","author":"Ortiz","year":"2011","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0685","series-title":"Cognitive Behavioral Treatment of Insomnia: A Session-by-Session Guide","author":"Perlis","year":"2005"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0690","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1016\/S0140-6736(13)60989-7","article-title":"Bipolar disorder diagnosis: challenges and future directions","volume":"381","author":"Phillips","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0695","doi-asserted-by":"crossref","first-page":"12019","DOI":"10.1073\/pnas.1901824116","article-title":"High sensitivity and interindividual variability in the response of the human circadian system to evening light","volume":"116","author":"Phillips","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0700","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1001\/archpsyc.65.9.1072","article-title":"Seasonal variation in human brain serotonin transporter binding","volume":"65","author":"Praschak-Rieder","year":"2008","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0705","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/nature12886","article-title":"The complete genome sequence of a Neanderthal from the Altai Mountains","volume":"505","author":"Pr\u00fcfer","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0710","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.1210\/endo-117-6-2505","article-title":"Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation","volume":"117","author":"Reul","year":"1985","journal-title":"Endocrinology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0715","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1001\/archneurpsyc.1938.02270030165012","article-title":"Two day cycles of alternating good and bad behavior in psychotic patients","volume":"39","author":"Richter","year":"1938","journal-title":"Arch. Neurol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0720","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1073\/pnas.46.11.1506","article-title":"Biological clocks in medicine and psychiatry: shock-phase hypothesis","volume":"46","author":"Richter","year":"1960","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0725","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.maturitas.2015.03.016","article-title":"Thyroid hormone: influences on mood and cognition in adults","volume":"81","author":"Ritchie","year":"2015","journal-title":"Maturitas"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0730","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1210\/endo-113-3-939","article-title":"Interaction of corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin secretion in vivo","volume":"113","author":"Rivier","year":"1983","journal-title":"Endocrinology"},{"issue":"7","key":"10.1016\/j.neubiorev.2020.05.017_bib0735","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.eurpsy.2013.04.001","article-title":"Sleep-wake cycle and melatonin rhythms in adolescents and young adults with mood disorders: comparison of unipolar and bipolar phenotypes","volume":"28","author":"Robillard","year":"2013","journal-title":"Eur. Psychiatry"},{"issue":"2","key":"10.1016\/j.neubiorev.2020.05.017_bib0740","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.jad.2012.06.006","article-title":"Delayed sleep phase in young people with unipolar or bipolar affective disorders","volume":"145","author":"Robillard","year":"2013","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0745","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.jad.2020.01.151","article-title":"Evening chronotype as a discrete clinical subphenotype in bipolar disorder","volume":"266","author":"Romo-Nava","year":"2020","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0750","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0169-328X(98)00273-3","article-title":"Natural melatonin \u2018knockdown\u2019 in C57BL\/6J mice: rare mechanism truncates serotonin N-acetyltransferase","volume":"63","author":"Roseboom","year":"1998","journal-title":"Mol. Br. Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0755","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1021\/acschemneuro.8b00495","article-title":"Nanotechnology in neuroscience reveals that membrane mobility matters","volume":"10","author":"Rosenthal","year":"2019","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0760","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1038\/s41386-019-0337-4","article-title":"Switching winter and summer photoperiods in an animal model of bipolar disorder","volume":"44","author":"Rosenthal","year":"2019","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0765","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/j.1399-5618.2007.00505.x","article-title":"Circadian activity rhythm abnormalities in ill and recovered bipolar I disorder patients","volume":"10","author":"Salvatore","year":"2008","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0770","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1038\/nature12961","article-title":"The genomic landscape of Neanderthal ancestry in present-day humans","volume":"507","author":"Sankararaman","year":"2014","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.neubiorev.2020.05.017_bib0775","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1186\/s12888-017-1361-8","article-title":"Sleep characteristics in child and adolescent offspring of parents with bipolar disorder: a case control study","volume":"17","author":"Sebela","year":"2017","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0780","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1080\/07420528.2019.1630631","article-title":"Decreased need for sleep as an endophenotype of bipolar disorder: an actigraphy study","volume":"36","author":"Sebela","year":"2019","journal-title":"Chronobiol. Int."},{"issue":"2","key":"10.1016\/j.neubiorev.2020.05.017_bib0785","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jad.2003.09.011","article-title":"Profiles of \u201cmanic\u201d symptoms in bipolar I, bipolar II and major depressive disorders","volume":"84","author":"Serretti","year":"2005","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0790","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.mehy.2011.10.005","article-title":"Evolutionary origin of bipolar disorder-revised (EOBD-R)","volume":"78","author":"Sherman","year":"2012","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0795","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1124\/pr.55.2.2","article-title":"Generation of the melatonin endocrine messagein mammals: a review of the complex regulation of melatonin synthesis by norepinephrine, peptides, and other pineal transmitters","volume":"55","author":"Simonneaux","year":"2003","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0800","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1126\/science.aad2149","article-title":"The phenotypic legacy of admixture between modern humans and Neandertals","volume":"351","author":"Simonti","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0805","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1111\/j.1399-5618.2007.00451.x","article-title":"Light therapy for bipolar disorder: a case series in women","volume":"9","author":"Sit","year":"2007","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0810","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1038\/ng.943","article-title":"Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4","volume":"43","author":"Sklar","year":"2011","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0815","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.physbeh.2016.11.014","article-title":"A users guide to HPA axis research","volume":"178","author":"Spencer","year":"2017","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0820","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/s41588-019-0397-8","article-title":"Genome-wide association study identifies 30 loci associated with bipolar disorder","volume":"51","author":"Stahl","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0825","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0165-1781(94)90015-9","article-title":"Lithium sustains the acute antidepressant e\ufb00 ;ects of sleep deprivation: preliminary \ufb01ndings from a controlled study","volume":"51","author":"Szuba","year":"1994","journal-title":"Psychiatry Res."},{"issue":"7","key":"10.1016\/j.neubiorev.2020.05.017_bib0830","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0159578","article-title":"Prevalence of circadian rhythm sleep-wake disorders and associated factors in euthymic patients with bipolar disorder","volume":"11","author":"Takaesu","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0835","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/pcn.12976","article-title":"Efficacy and safety of bright light therapy for manic and depressive symptoms in patients with bipolar disorder: a systematic review and meta-analysis","volume":"74","author":"Takeshima","year":"2020","journal-title":"Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0840","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/acps.12517","article-title":"Suicide attempts in bipolar disorders: comprehensive review of 101 reports","volume":"133","author":"Tondo","year":"2016","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0845","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.euroneuro.2016.03.001","article-title":"Light therapy in the treatment of patients with bipolar depression: a meta-analytic study","volume":"26","author":"Tseng","year":"2016","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0850","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1159\/000468102","article-title":"Certain circadian rhythms in manic-depressives and their response to lithium","volume":"5","author":"Turpin","year":"1970","journal-title":"Int. Pharmacopsychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0855","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1176\/ajp.125.4.536","article-title":"Lithium effects on electrolyte excretion","volume":"125","author":"Turpin","year":"1968","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0860","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1038\/npp.2016.54","article-title":"Increased seasonal variation in serotonin transporter binding in seasonal affective disorder","volume":"41","author":"Tyrer","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0865","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1586\/14737175.2014.915744","article-title":"Corticolimbic connectivity as a possible biomarker for bipolar disorder","volume":"14","author":"Vai","year":"2014","journal-title":"Expert Rev. Neurother."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0870","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1126\/science.6267699","article-title":"Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and \u03b2-endorphin","volume":"213","author":"Vale","year":"1981","journal-title":"Science"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0875","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.cub.2007.01.048","article-title":"Seasonal encoding by the circadian pacemaker of the SCN","volume":"17","author":"VandeLeest","year":"2007","journal-title":"Curr. Biol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0880","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S0010-440X(97)90088-2","article-title":"Differential features between bipolar I and bipolar II disorder","volume":"38","author":"Vieta","year":"1997","journal-title":"Compr. Psychiat."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0885","doi-asserted-by":"crossref","first-page":"18008","DOI":"10.1038\/nrdp.2018.8","article-title":"Bipolar disorders","volume":"4","author":"Vieta","year":"2018","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0890","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41398-020-0694-0","article-title":"Circadian rhythm disruption and mental health","volume":"10","author":"Walker","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0895","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/bdi.12657","article-title":"Adjunctive thyroid hormone treatment in rapid cycling bipolar disorder: a double-blind placebo-controlled trial of levothyroxine (L-T4) and triiodothyronine (T3)","volume":"20","author":"Walshaw","year":"2018","journal-title":"Bipolar Disord."},{"issue":"6","key":"10.1016\/j.neubiorev.2020.05.017_bib0900","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1192\/bjp.184.6.496","article-title":"Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder","volume":"184","author":"Watson","year":"2004","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0905","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.psyneuen.2006.03.001","article-title":"The dex\/CRH test\u2014is it better than the DST","volume":"31","author":"Watson","year":"2006","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0910","first-page":"231","article-title":"A \u2018clock for all seasons\u2019 in the human brain","volume":"111","author":"Wehr","year":"1996","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0915","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1126\/science.227056","article-title":"Phase advance of the circadian sleep-wake cycle as an antidepressant","volume":"206","author":"Wehr","year":"1979","journal-title":"Science"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0920","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1001\/archpsyc.1980.01780160027002","article-title":"Urinary 3-methoxy-4-hydroxyphenylglycol circadian rhythm. Early timing (phase advance) in manic-depressives compared to controls","volume":"37","author":"Wehr","year":"1980","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0925","first-page":"551","article-title":"Suprachiasmatic nucleus: cell autonomy and network properties","volume":"72","author":"Welsh","year":"2010","journal-title":"Annu. Rev. Plant Physiol. Plant Mol. Biol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0930","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1017\/S0033291707001420","article-title":"Twelve-month mental disorders in South Africa: prevalence, service use and demographic correlates in the population-based South African Stress and Health Study","volume":"38","author":"Williams","year":"2008","journal-title":"Psychol. Med. (Paris)"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0935","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/ejn.14362","article-title":"Perspectives in affective disorders: clocks and sleep","volume":"51","author":"Wirz-Justice","year":"2020","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0940","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/S0006-3223(98)00289-3","article-title":"A rapid cycling bipolar patient treated with long nights, bedrest and light","volume":"45","author":"Wirz-Justice","year":"1999","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0945","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1017\/S003329170500437X","article-title":"Chronotherapeutics (light and wake therapy) in affective disorders","volume":"35","author":"Wirz-Justice","year":"2005","journal-title":"Psychol. Med. (Paris)"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0950","series-title":"Chronotherapeutics for Affective Disorders","author":"Wirz-Justice","year":"2013"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0955","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/sleep\/34.3.261","article-title":"Evidence for neuroinflammatory and microglial changes in the cerebral response to sleep loss","volume":"34","author":"Wisor","year":"2011","journal-title":"Sleep"},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0960","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.psychres.2008.03.003","article-title":"Replicable differences in preferred circadian phase between bipolar disorder patients and control individuals","volume":"166","author":"Wood","year":"2009","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0965","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1016\/j.cub.2013.06.039","article-title":"Entrainment of the human circadian clock to the natural light-dark cycle","volume":"23","author":"Wright","year":"2013","journal-title":"Curr. Biol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0970","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.ejphar.2015.03.019","article-title":"Investigating the mechanism(s) underlying switching between states in bipolar disorder","volume":"759","author":"Young","year":"2015","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neubiorev.2020.05.017_bib0975","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1038\/s41386-018-0031-y","article-title":"Mice with reduced DAT levels recreate seasonal-induced switching between states in bipolar disorder","volume":"43","author":"Young","year":"2018","journal-title":"Neuropsychopharmacology"}],"container-title":["Neuroscience & Biobehavioral Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763420304206?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763420304206?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T09:40:43Z","timestamp":1758966043000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0149763420304206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":195,"alternative-id":["S0149763420304206"],"URL":"https:\/\/doi.org\/10.1016\/j.neubiorev.2020.05.017","relation":{},"ISSN":["0149-7634"],"issn-type":[{"value":"0149-7634","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Seasonal effects on bipolar disorder: A closer look","name":"articletitle","label":"Article Title"},{"value":"Neuroscience & Biobehavioral Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neubiorev.2020.05.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}