{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:18:26Z","timestamp":1792642706685,"version":"4.5.0"},"reference-count":284,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000848","name":"University of Edinburgh","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009147","name":"College of Medicine and Veterinary Medicine, University of Edinburgh","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009147","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015504","name":"Simons Initiative for the Developing Brain","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015504","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience &amp; Biobehavioral Reviews"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.neubiorev.2021.07.014","type":"journal-article","created":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T15:42:34Z","timestamp":1626277354000},"page":"35-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":158,"special_numbering":"C","title":["The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders"],"prefix":"10.1016","volume":"129","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1152-8292","authenticated-orcid":false,"given":"Rana","family":"Fetit","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2595-552X","authenticated-orcid":false,"given":"Robert F.","family":"Hillary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5318-307X","authenticated-orcid":false,"given":"David J.","family":"Price","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M.","family":"Lawrie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neubiorev.2021.07.014_bib0005","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10048-008-0133-5","article-title":"Heterogeneous dysregulation of microRNAs across the autism spectrum","volume":"9","author":"Abu-Elneel","year":"2008","journal-title":"Neurogenetics"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0010","doi-asserted-by":"crossref","first-page":"e1137","DOI":"10.1038\/tp.2017.104","article-title":"Shifting brain inhibitory balance and connectivity of the prefrontal cortex of adults with autism spectrum disorder","volume":"7","author":"Ajram","year":"2017","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0015","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.pnpbp.2018.09.010","article-title":"The contribution of [1H] magnetic resonance spectroscopy to the study of excitation-inhibition in autism","volume":"89","author":"Ajram","year":"2019","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0020","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/aur.2205","article-title":"Increased expression of miR\u2010155p5 in amygdala of children With Autism Spectrum Disorder","volume":"13","author":"Almehmadi","year":"2020","journal-title":"Autism Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0025","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0896-6273(04)00111-4","article-title":"For the long run: maintaining germinal niches in the adult brain","volume":"41","author":"Alvarez-Buylla","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0030","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/B978-0-444-63639-3.00003-7","article-title":"Autism BrainNet: a network of postmortem brain banks established to facilitate autism research","volume":"150","author":"Amaral","year":"2018","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0035","series-title":"Brain Banking","article-title":"Autism BrainNet a network of postmortem brain banks established to facilitate autism research","author":"Amaral","year":"2018"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0040","series-title":"Scientists Rise up Against Statistical Significance","author":"Amrhein","year":"2019"},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0045","doi-asserted-by":"crossref","DOI":"10.1186\/s13229-015-0029-9","article-title":"Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders","volume":"6","author":"Ander","year":"2015","journal-title":"Mol. Autism"},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0050","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-3-12","article-title":"Brain region-specific altered expression and association of mitochondria-related genes in autism","volume":"3","author":"Anitha","year":"2012","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0055","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/bpa.12002","article-title":"Downregulation of the expression of mitochondrial electron transport complex genes in autism brains","volume":"23","author":"Anitha","year":"2013","journal-title":"Brain Pathol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0060","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1503\/jpn.130126","article-title":"Zinc finger protein 804A (ZNF804A) and verbal deficits in individuals with autism","volume":"39","author":"Anitha","year":"2014","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0065","doi-asserted-by":"crossref","first-page":"601","DOI":"10.3389\/fnins.2016.00601","article-title":"Variation in gene expression in autism spectrum disorders: an extensive review of transcriptomic studies","volume":"10","author":"Ansel","year":"2017","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0070","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1023\/B:CEMN.0000005322.27203.73","article-title":"Levels of Bcl-2 and P53 are altered in superior frontal and cerebellar cortices of autistic subjects","volume":"23","author":"Araghi-Niknam","year":"2003","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0075","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.brainres.2014.11.058","article-title":"Dysregulated iron metabolism in the choroid plexus in fragile X-associated tremor\/ataxia syndrome","volume":"1598","author":"Ariza","year":"2015","journal-title":"Brain Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0080","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00005072-199503000-00006","article-title":"Selective dendritic alterations in the cortex of Rett syndrome","volume":"54","author":"Armstrong","year":"1995","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0085","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1177\/08830738030180100601","article-title":"Survey of MeCP2 in the rett syndrome and the non-rett syndrome brain","volume":"18","author":"Armstrong","year":"2003","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0090","series-title":"Diagnostic and Statistical Manual of Mental Disorders (DSM-5\u00ae)","author":"Association","year":"2013"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0095","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1002\/ar.21243","article-title":"Dystrophic serotonin axons in postmortem brains from young autism patients","volume":"294","author":"Azmitia","year":"2011","journal-title":"Anat. Rec."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0100","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/j.neuropharm.2011.02.002","article-title":"Increased serotonin axons (immunoreactive to 5-HT transporter) in postmortem brains from young autism donors","volume":"60","author":"Azmitia","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0105","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1007\/s10803-015-2672-6","article-title":"Persistent angiogenesis in the autism brain: an immunocytochemical study of postmortem cortex, brainstem and cerebellum","volume":"46","author":"Azmitia","year":"2016","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0110","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/brain\/121.5.889","article-title":"A clinicopathological study of autism","volume":"121","author":"Bailey","year":"1998","journal-title":"Brain: J. Neurol."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0115","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-5-49","article-title":"Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHTM2 and WIZ, in Japanese autism subjects","volume":"5","author":"Balan","year":"2014","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0120","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1212\/WNL.35.6.866","article-title":"Histoanatomic observations of the brain in early infantile autism","volume":"35","author":"Bauman","year":"1985","journal-title":"Neurology"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0125","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.ijdevneu.2004.09.006","article-title":"Neuroanatomic observations of the brain in autism: a review and future directions","volume":"23","author":"Bauman","year":"2005","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0130","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1212\/WNL.45.8.1581","article-title":"Pervasive neuroanatomic abnormalities of the brain in three cases of Rett\u2019s syndrome","volume":"45","author":"Bauman","year":"1995","journal-title":"Neurology"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0135","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.tins.2004.04.009","article-title":"The mGluR theory of fragile X mental retardation","volume":"27","author":"Bear","year":"2004","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0140","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1038\/s41380-019-0420-6","article-title":"Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder","volume":"25","author":"Bedford","year":"2020","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0145","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1097\/00001756-199407000-00025","article-title":"Rett syndrome: 3-D confocal microscopy of cortical pyramidal dendrites and afferents","volume":"5","author":"Belichenko","year":"1994","journal-title":"Neuroreport: Int. J. Rapid Commun. Res. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0150","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1001\/jama.1994.03520100096046","article-title":"DSM-IV: diagnostic and statistical manual of mental disorders","volume":"272","author":"Bell","year":"1994","journal-title":"Jama"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0155","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s00401-008-0360-8","article-title":"Management of a twenty-first century brain bank: experience in the BrainNet Europe consortium","volume":"115","author":"Bell","year":"2008","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0160","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1093\/scan\/nsp053","article-title":"The principled control of false positives in neuroimaging","volume":"4","author":"Bennett","year":"2009","journal-title":"Soc. Cogn. Affect. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0165","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1006\/exnr.1999.7030","article-title":"Altered development of glutamate and GABA receptors in the basal ganglia of girls with Rett syndrome","volume":"156","author":"Blue","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0170","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/nrn3992","article-title":"From the genetic architecture to synaptic plasticity in autism spectrum disorder","volume":"16","author":"Bourgeron","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0175","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1111\/ejn.13595","article-title":"Neurobiological bases of autism\u2013epilepsy comorbidity: a focus on excitation\/inhibition imbalance","volume":"47","author":"Bozzi","year":"2018","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0180","first-page":"20","article-title":"Differential serotonin transporter (5-HTT) and 5-HT<inf>2<\/inf> receptor density in limbic and neocortical areas of adults and children with ASD: implications for SSRI efficacy","author":"Brandenburg","year":"2019","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0185","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-5-41","article-title":"Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins","volume":"5","author":"Broek","year":"2014","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0190","doi-asserted-by":"crossref","first-page":"232","DOI":"10.3389\/fnhum.2013.00232","article-title":"Segregation of the human medial prefrontal cortex in social cognition","volume":"7","author":"Bzdok","year":"2013","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0195","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.conb.2019.01.004","article-title":"New insights on synaptic dysfunction in neuropsychiatric disorders","volume":"57","author":"Caldeira","year":"2019","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0200","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.neulet.2014.07.031","article-title":"RELN-expressing neuron density in layer I of the superior temporal lobe is similar in human brains with autism and in age-matched controls","volume":"579","author":"Camacho","year":"2014","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0205","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/ana.21180","article-title":"Disruption of cerebral cortex MET signaling in autism spectrum disorder","volume":"62","author":"Campbell","year":"2007","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0210","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00787-006-0563-2","article-title":"Epilepsy in autism spectrum disorders","volume":"16","author":"Canitano","year":"2007","journal-title":"Eur. Child Adolesc. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0215","series-title":"The Molecular Basis of Autism","article-title":"The neuropathology of autism","author":"Casanova","year":"2015"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0220","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1212\/WNL.58.3.428","article-title":"Minicolumnar pathology in autism","volume":"58","author":"Casanova","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0225","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1177\/088307380201700708","article-title":"Neuronal density and architecture (Gray Level Index) in the brains of autistic patients","volume":"17","author":"Casanova","year":"2002","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0230","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.cnr.2006.06.003","article-title":"Abnormalities of cortical minicolumnar organization in the prefrontal lobes of autistic patients","volume":"6","author":"Casanova","year":"2006","journal-title":"Clin. Neurosci. Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0235","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s00401-006-0085-5","article-title":"Minicolumnar abnormalities in autism","volume":"112","author":"Casanova","year":"2006","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0240","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.bbi.2015.05.009","article-title":"Decreased expression of mGluR5 within the dorsolateral prefrontal cortex in autism and increased microglial number in mGluR5 knockout mice: pathophysiological and neurobehavioral implications","volume":"49","author":"Chana","year":"2015","journal-title":"Brain Behav. Immun."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0245","article-title":"NTRK2 expression levels are reduced in laser captured pyramidal neurons from the anterior cingulate cortex in males with autism spectrum disorder","volume":"6","author":"Chandley","year":"2015","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0250","doi-asserted-by":"crossref","first-page":"4277","DOI":"10.1038\/s41598-018-22753-4","article-title":"Allele-specific expression in a family quartet with autism reveals mono-to-biallelic switch and novel transcriptional processes of autism susceptibility genes","volume":"8","author":"Chang","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0255","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00315638","article-title":"Gamma-aminobutyric acid pathways in the cerebellum studied by retrograde and anterograde transport of glutamic acid decarboxylase antibody after in vivo injections","volume":"157","author":"Chan-Palay","year":"1979","journal-title":"Anat. Embryol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0260","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.nbd.2009.05.001","article-title":"Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations","volume":"35","author":"Chapleau","year":"2009","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0265","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ijdevneu.2014.03.006","article-title":"Dysregulation of the IGF-I\/PI3K\/AKT\/mTOR signaling pathway in autism spectrum disorders","volume":"35","author":"Chen","year":"2014","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0270","doi-asserted-by":"crossref","first-page":"2955","DOI":"10.1093\/hmg\/ddy193","article-title":"5-Hydroxymethylcytosine alterations in the human postmortem brains of autism spectrum disorder","volume":"27","author":"Cheng","year":"2018","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0275","first-page":"9","article-title":"Autism associated gene, ENGRAILED2, and flanking gene levels are altered in post-mortem cerebellum","volume":"9","author":"Choi","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0280","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002592","article-title":"Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages","volume":"8","author":"Chow","year":"2012","journal-title":"PLoS Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0285","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1001\/jamapsychiatry.2018.1100","article-title":"Evaluation of the social motivation hypothesis of autism: a systematic review and meta-analysis","volume":"75","author":"Clements","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0290","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1006\/nbdi.2001.0428","article-title":"Gene expression profiling in postmortem Rett Syndrome brain: differential gene expression and patient classification","volume":"8","author":"Colantuoni","year":"2001","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0295","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/BF01531496","article-title":"Cell counts in cerebral cortex of an autistic patient","volume":"15","author":"Coleman","year":"1985","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0300","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0092-8674(00)80778-3","article-title":"Lipoprotein receptors: signaling functions in the brain?","volume":"97","author":"Cooper","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0305","first-page":"577","article-title":"Autism at the beginning: microstructural and growth abnormalities underlying the cognitive and behavioral phenotype of autism","volume":"17","author":"Courchesene","year":"2005","journal-title":"Dev. Psychopathol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0310","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1212\/WNL.52.5.1057","article-title":"Brain weight in autism: normal in the majority of cases, megalencephalic in rare cases","volume":"52","author":"Courchesne","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0315","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1001\/jama.290.3.337","article-title":"Evidence of brain overgrowth in the first year of life in autism","volume":"290","author":"Courchesne","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0320","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1001\/jama.2011.1638","article-title":"Neuron number and size in prefrontal cortex of children with autism","volume":"306","author":"Courchesne","year":"2011","journal-title":"Jama J. Am. Med. Assoc."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0325","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41380-018-0056-y","article-title":"The ASD living biology: from cell proliferation to clinical phenotype","volume":"24","author":"Courchesne","year":"2019","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0330","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1002\/aur.1480","article-title":"Elevated GFAP protein in anterior cingulate cortical white matter in males with autism spectrum disorder","volume":"8","author":"Crawford","year":"2015","journal-title":"Autism Res."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0335","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-5-45","article-title":"Ubiquitin-proteasome dependent degradation of GABA<inf>A<\/inf>alpha1 in autism spectrum disorder","volume":"5","author":"Crider","year":"2014","journal-title":"Mol. Autism"},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0340","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-5-46","article-title":"Dysregulation of estrogen receptor beta (ERbeta), aromatase (CYP19A1), and ER co-activators in the middle frontal gyrus of autism spectrum disorder subjects","volume":"5","author":"Crider","year":"2014","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0345","first-page":"85","article-title":"Altered expression of endoplasmic reticulum stress-related genes in the middle frontal cortex of subjects with Autism Spectrum Disorder","volume":"3","author":"Crider","year":"2017","journal-title":"Mol. Neuropsychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0350","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13229-020-00339-0","article-title":"Exploring the mechanisms underlying excitation\/inhibition imbalance in human iPSC-derived models of ASD","volume":"11","author":"Culotta","year":"2020","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0355","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.neuron.2015.11.009","article-title":"Targeted DNA sequencing from Autism Spectrum Disorder brains implicates multiple genetic mechanisms","volume":"88","author":"D\u2019Gama","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0360","first-page":"10","article-title":"Prenatal exposure to a common organophosphate insecticide delays motor development in a mouse model of idiopathic autism","author":"De Felice","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0365","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/nature13772","article-title":"Synaptic, transcriptional and chromatin genes disrupted in autism","volume":"515","author":"De Rubeis","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0370","first-page":"08","article-title":"T-lymphocytes and Cytotoxic Astrocyte Blebs Correlate Across Autism Brains","author":"Distasio","year":"2019","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0375","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1089\/scd.2010.0224","article-title":"Forced expression of LIM homeodomain transcription factor 1b enhances differentiation of mouse embryonic stem cells into serotonergic neurons","volume":"20","author":"Dolmazon","year":"2011","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0380","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s11065-015-9300-2","article-title":"A comparison of structural brain imaging findings in autism spectrum disorder and attention-deficit hyperactivity disorder","volume":"26","author":"Dougherty","year":"2016","journal-title":"Neuropsychol. Rev."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0385","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-5-3","article-title":"Altered glial marker expression in autistic post-mortem prefrontal cortex and cerebellum","volume":"5","author":"Edmonson","year":"2014","journal-title":"Mol. Autism"},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0390","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-2-6","article-title":"Dysregulation of fragile X mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study","volume":"2","author":"Fatemi","year":"2011","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0395","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.schres.2014.10.010","article-title":"GABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism","volume":"167","author":"Fatemi","year":"2015","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0400","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/syn.10002","article-title":"Altered levels of Bcl2 and p53 proteins in parietal cortex reflect deranged apoptotic regulation in autism","volume":"42","author":"Fatemi","year":"2001","journal-title":"Synapse"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0405","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1023\/A:1013234708757","article-title":"Dysregulation of Reelin and Bcl-2 proteins in autistic cerebellum","volume":"31","author":"Fatemi","year":"2001","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0410","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0006-3223(02)01430-0","article-title":"Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices","volume":"52","author":"Fatemi","year":"2002","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0415","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1023\/A:1019861721160","article-title":"Purkinje cell size is reduced in cerebellum of patients with autism","volume":"22","author":"Fatemi","year":"2002","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0420","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.biopsych.2004.12.018","article-title":"Reelin signaling is impaired in autism","volume":"57","author":"Fatemi","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0425","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1002\/syn.20519","article-title":"Expression of astrocytic markers aquaporin 4 and connexin 43 is altered in brains of subjects with autism","volume":"62","author":"Fatemi","year":"2008","journal-title":"Synapse"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0430","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1007\/s12311-008-0075-3","article-title":"Expression of GABA<inf>B<\/inf> Receptors Is Altered in Brains of Subjects with Autism","volume":"8","author":"Fatemi","year":"2009","journal-title":"Cerebellum"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0435","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s10803-008-0646-7","article-title":"GABA(A) receptor downregulation in brains of subjects with autism","volume":"39","author":"Fatemi","year":"2009","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0440","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1002\/ar.21299","article-title":"Metabotropic glutamate Receptor 5 upregulation in children with autism is associated with underexpression of both fragile X mental retardation protein and GABA<inf>A<\/inf> receptor beta 3 in adults with autism","volume":"294","author":"Fatemi","year":"2011","journal-title":"Anat. Rec."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0445","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-4-21","volume":"4","author":"Fatemi","year":"2013","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0450","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1093\/cercor\/4.4.408","article-title":"Minicolumnar organization within somatosensory cortical segregates: I. Development of afferent connections","volume":"4","author":"Favorov","year":"1994","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0455","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1093\/cercor\/4.4.428","article-title":"Minicolumnar organization within somatosensory cortical segregates: II. Emergent functional properties","volume":"4","author":"Favorov","year":"1994","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0460","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1136\/jmg.2009.069369","article-title":"Phenotypic spectrum associated with de novo and inherited deletions and duplications at 16p11. 2 in individuals ascertained for diagnosis of autism spectrum disorder","volume":"47","author":"Fernandez","year":"2010","journal-title":"J. Med. Genet."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0465","doi-asserted-by":"crossref","DOI":"10.1186\/s13229-016-0110-z","article-title":"Blood-brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders","volume":"7","author":"Fiorentino","year":"2016","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0470","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1203\/PDR.0b013e31819e7203","article-title":"Epidemiology of pervasive developmental disorders","volume":"65","author":"Fombonne","year":"2009","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0475","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.biopsych.2017.03.005","article-title":"Searching for cross-diagnostic convergence: neural mechanisms governing excitation and inhibition balance in schizophrenia and autism spectrum disorders","volume":"81","author":"Foss-Feig","year":"2017","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0480","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s10803-010-0981-3","article-title":"Motor coordination in autism spectrum disorders: a synthesis and meta-analysis","volume":"40","author":"Fournier","year":"2010","journal-title":"J. Autism Dev. Disord."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0485","doi-asserted-by":"crossref","DOI":"10.1038\/s41398-018-0315-3","article-title":"Effect of age and autism spectrum disorder on oxytocin receptor density in the human basal forebrain and midbrain","volume":"8","author":"Freeman","year":"2018","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0490","doi-asserted-by":"crossref","first-page":"394","DOI":"10.3389\/fped.2018.00394","article-title":"Modeling Inflammation in autism spectrum disorders using stem cells","volume":"6","author":"Freitas","year":"2018","journal-title":"Front. Pediatr."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0495","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/608654","article-title":"Microglial dysregulation in psychiatric disease","volume":"2013","author":"Frick","year":"2013","journal-title":"Clin. Dev. Immunol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0500","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.nbd.2008.01.012","article-title":"Immune transcriptome alterations in the temporal cortex of subjects with autism","volume":"30","author":"Garbett","year":"2008","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0505","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/NEN.0b013e31824b27e4","article-title":"Altered balance of proteolytic isoforms of pro-brain-derived neurotrophic factor in autism","volume":"71","author":"Garcia","year":"2012","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0510","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1471-2202-11-53","article-title":"Downstream targets of methyl CpG binding protein 2 and their abnormal expression in the frontal cortex of the human Rett syndrome brain","volume":"11","author":"Gibson","year":"2010","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0515","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1016\/j.celrep.2014.10.064","article-title":"Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X Syndrome-like phenotypes","volume":"9","author":"Gkogkas","year":"2014","journal-title":"Cell Rep."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0520","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1093\/hmg\/ddw074","article-title":"mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome","volume":"25","author":"Gogliotti","year":"2016","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0525","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1124\/jpet.117.246991","article-title":"Total RNA sequencing of rett syndrome autopsy samples identifies the M<inf>4<\/inf> muscarinic receptor as a novel therapeutic target","volume":"365","author":"Gogliotti","year":"2018","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0530","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s11306-016-0986-9","article-title":"High resolution metabolomic analysis of ASD human brain uncovers novel biomarkers of disease","volume":"12","author":"Graham","year":"2016","journal-title":"Metabolomics"},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0535","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-2-2","article-title":"Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome","volume":"2","author":"Greco","year":"2011","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0540","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s00439-016-1673-7","article-title":"Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis","volume":"135","author":"Guan","year":"2016","journal-title":"Hum. Genet."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0545","doi-asserted-by":"crossref","DOI":"10.1038\/s41398-019-0488-4","article-title":"Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder","volume":"9","author":"Guan","year":"2019","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0550","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1093\/cercor\/bhu242","article-title":"Anatomical abnormalities in autism?","volume":"26","author":"Haar","year":"2014","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0555","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/ana.410140412","article-title":"A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: rett\u2019s syndrome: report of 35 cases","volume":"14","author":"Hagberg","year":"1983","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0560","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S0387-7604(85)80048-6","article-title":"Rett syndrome: criteria for inclusion and exclusion","volume":"7","author":"Hagberg","year":"1985","journal-title":"Brain Dev."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0565","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s11689-011-9084-5","article-title":"FMR1 premutation and full mutation molecular mechanisms related to autism","volume":"3","author":"Hagerman","year":"2011","journal-title":"J. Neurodev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0570","first-page":"1931","article-title":"The number of parvalbumin-expressing interneurons is decreased in the medial prefrontal cortex in autism","volume":"27","author":"Hashemi","year":"2017","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0575","series-title":"Neuropsychiatric \u201cComorbidity\u201d as Causal Influence in Autism","author":"Hawks","year":"2020"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0580","doi-asserted-by":"crossref","first-page":"3460","DOI":"10.1007\/s10803-018-3613-y","article-title":"Cerebro-cerebellar functional connectivity is associated with cerebellar excitation\u2013inhibition balance in autism spectrum disorder","volume":"48","author":"Hegarty","year":"2018","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0585","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/ajmg.1320410306","article-title":"Analysis of neocortex in three males with the fragile X syndrome","volume":"41","author":"Hinton","year":"1991","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0590","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1136\/jmg.2008.061580","article-title":"Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number","volume":"46","author":"Hogart","year":"2009","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0595","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/39607","article-title":"Neuronal position in the developing brain is regulated by mouse disabled-1","volume":"389","author":"Howell","year":"1997","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0600","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-6-7","article-title":"Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism","volume":"6","author":"Hu","year":"2015","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0605","doi-asserted-by":"crossref","first-page":"7746","DOI":"10.1073\/pnas.122205699","article-title":"Altered synaptic plasticity in a mouse model of fragile X mental retardation","volume":"99","author":"Huber","year":"2002","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0610","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.biopsych.2006.01.015","article-title":"Histological and magnetic resonance imaging assessment of cortical layering and thickness in autism Spectrum disorders","volume":"61","author":"Hutsler","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0615","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.brainres.2009.09.120","article-title":"Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders","volume":"1309","author":"Hutsler","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0620","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/1096-8628(20010115)98:2<161::AID-AJMG1025>3.0.CO;2-B","article-title":"Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile\u2010X syndrome: a quantitative examination","volume":"98","author":"Irwin","year":"2001","journal-title":"Am. J. Med. Genet."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib0625","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-5-33","article-title":"N-ethylmaleimide-sensitive factor interacts with the serotonin transporter and modulates its trafficking: implications for pathophysiology in autism","volume":"5","author":"Iwata","year":"2014","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0630","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2013.8","article-title":"Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum","volume":"3","author":"James","year":"2013","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0635","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/ajmg.1320250528","article-title":"Neuropathology of rett syndrome","volume":"24","author":"Jellinger","year":"1986","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0640","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1007\/BF00688098","article-title":"Neuropathology of rett syndrome","volume":"76","author":"Jellinger","year":"1988","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0645","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/ajmg.a.30349","article-title":"Proteomic studies identified a single nucleotide polymorphism in glyoxalase I as autism susceptibility factor","volume":"131","author":"Junaid","year":"2004","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0650","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.nicl.2018.06.002","article-title":"Diffusion-weighted imaging evidence of altered white matter development from late childhood to early adulthood in autism spectrum disorder","volume":"19","author":"Karahano\u011flu","year":"2018","journal-title":"Neuroimage Clin."},{"issue":"431","key":"10.1016\/j.neubiorev.2021.07.014_bib0655","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aaf6060","article-title":"Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome","volume":"9","author":"Kashima","year":"2016","journal-title":"Sci. Signal."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0660","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1093\/cercor\/10.10.992","article-title":"Dendritic cytoskeletal protein expression in mental retardation: an immunohistochemical study of the neocortex in Rett syndrome","volume":"10","author":"Kaufmann","year":"2000","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0665","doi-asserted-by":"crossref","first-page":"S194","DOI":"10.1542\/peds.2016-1159F","article-title":"Autism spectrum disorder in fragile X syndrome: cooccurring conditions and current treatment","volume":"139","author":"Kaufmann","year":"2017","journal-title":"Pediatrics"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0670","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0733-8619(18)30176-2","article-title":"The contribution of neuropathologic studies to the understanding of autism","volume":"11","author":"Kemper","year":"1993","journal-title":"Neurol. Clin."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0675","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.bandc.2007.01.007","article-title":"No reduction of spindle neuron number in frontoinsular cortex in autism","volume":"64","author":"Kennedy","year":"2007","journal-title":"Brain Cogn."},{"issue":"128","key":"10.1016\/j.neubiorev.2021.07.014_bib0680","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3003479","article-title":"A noncoding RNA antisense to moesin at 5p14.1 in autism","volume":"4","author":"Kerin","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0685","first-page":"257","article-title":"Disrupted brain thyroid hormone homeostasis and altered thyroid hormone-dependent brain gene expression in autism spectrum disorders","volume":"65","author":"Khan","year":"2014","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0690","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/cercor\/bhn066","article-title":"Neuropathologic features in adults with 22q11. 2 deletion syndrome","volume":"19","author":"Kiehl","year":"2009","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0695","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1126\/science.1088545","article-title":"The architecture of cognitive control in the human prefrontal cortex","volume":"302","author":"Koechlin","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0700","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/dneu.22127","article-title":"Subventricular zone cytoarchitecture changes in Autism","volume":"74","author":"Kotagiri","year":"2014","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0705","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/nn.2321","article-title":"Motivation and cognitive control in the human prefrontal cortex","volume":"12","author":"Kouneiher","year":"2009","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0710","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.heares.2006.12.006","article-title":"Cytoarchitecture of the human superior olivary complex: medial and lateral superior olive","volume":"225","author":"Kulesza","year":"2007","journal-title":"Hear. Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0715","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.brainres.2008.01.009","article-title":"Morphological features of the medial superior olive in autism","volume":"1200","author":"Kulesza","year":"2008","journal-title":"Brain Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0720","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0014-4827(86)90520-3","article-title":"Expression of proliferating cell nuclear antigen (PCNA)\/cyclin during the cell cycle","volume":"166","author":"Kurki","year":"1986","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0725","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1038\/mp.2013.114","article-title":"Common DNA methylation alterations in multiple brain regions in autism","volume":"19","author":"Ladd-Acosta","year":"2014","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0730","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/jnr.23948","article-title":"Imaging sex\/gender and autism in the brain: etiological implications","volume":"95","author":"Lai","year":"2017","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0735","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S2215-0366(19)30289-5","article-title":"Prevalence of co-occurring mental health diagnoses in the autism population: a systematic review and meta-analysis","volume":"6","author":"Lai","year":"2019","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0740","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1080\/14734220500208846","article-title":"Glial fibrillary acidic protein is elevated in superior frontal, parietal and cerebellar cortices of autistic subjects","volume":"4","author":"Laurence","year":"2005","journal-title":"Cerebellum"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0745","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1600-0404.2009.01234.x","article-title":"Parvalbumin-, calbindin-, and calretinin-immunoreactive hippocampal interneuron density in autism","volume":"121","author":"Lawrence","year":"2010","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0750","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1093\/brain\/awf160","article-title":"Nicotinic receptor abnormalities in the cerebellar cortex in autism","volume":"125","author":"Lee","year":"2002","journal-title":"Brain: J. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0755","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1744-9081-1-15","article-title":"Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia","volume":"1","author":"Lee","year":"2005","journal-title":"Behav. Brain Funct."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0760","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.bbi.2017.01.019","article-title":"Developmental microglial priming in postmortem autism spectrum disorder temporal cortex","volume":"62","author":"Lee","year":"2017","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0765","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1038\/s41593-019-0461-9","article-title":"Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage","volume":"22","author":"Lee","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0770","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/ajmg.b.32701","article-title":"Solving for X: evidence for sex-specific autism biomarkers across multiple transcriptomic studies","volume":"180","author":"Lee","year":"2019","journal-title":"Am. J. Med. Genet. Part B Neuropsychiatr. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0775","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0887-8994(89)90049-0","article-title":"Rett syndrome: biogenic amines and metabolites in postmortem brain","volume":"5","author":"Lekman","year":"1989","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0780","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/sj.mp.4002120","article-title":"SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects","volume":"13","author":"Lepagnol-Bestel","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0785","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0893-133X(01)00393-1","article-title":"The human brain revisited: opportunities and challenges in postmortem studies of psychiatric disorders","volume":"26","author":"Lewis","year":"2002","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0790","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/mp.2008.21","article-title":"Involvement of the PRKCB1 gene in autistic disorder: significant genetic association and reduced neocortical gene expression","volume":"14","author":"Lintas","year":"2009","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0795","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/jnen\/59.10.889","article-title":"Reduced nerve growth factor in Rett syndrome postmortem brain tissue","volume":"59","author":"Lipani","year":"2000","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0800","series-title":"The Synaptic Organization of the Brain","author":"Llin\u00e1s","year":"2004"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0805","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1111\/j.1601-183X.2008.00414.x","article-title":"Methyl\u2010CpG\u2010binding protein 2 polymorphisms and vulnerability to autism","volume":"7","author":"Loat","year":"2008","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0810","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/ajmg.b.10016","article-title":"Absence of MeCP2 mutations in patients from the South Carolina autism project","volume":"117","author":"Lobo\u2010Menendez","year":"2003","journal-title":"Am. J. Med. Genet. Part B Neuropsychiatr. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0815","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/2040-2392-4-15","article-title":"Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?","volume":"4","author":"Lohith","year":"2013","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0820","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.tins.2014.10.003","article-title":"Categorical diagnosis: a fatal flaw for autism research?","volume":"37","author":"London","year":"2014","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0825","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/BF02172145","article-title":"Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders","volume":"24","author":"Lord","year":"1994","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0830","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1023\/A:1025873925661","article-title":"Diagnosing autism: analyses of data from the Autism Diagnostic Interview","volume":"27","author":"Lord","year":"1997","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0835","series-title":"Autism Diagnostic Observation Schedule--Generic. Dissertation Abstracts International Section A: Humanities and Social Sciences","author":"Lord","year":"1999"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0840","first-page":"970","article-title":"Neurobiological foundations of multisensory integration in people with autism spectrum disorders: the role of the medial prefrontal cortex","volume":"8","author":"Mart\u00ednez-Sanchis","year":"2014","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0845","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.bbr.2018.06.023","article-title":"Increased expression of BDNF mRNA in the frontal cortex of autistic patients","volume":"359","author":"Maussion","year":"2019","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0850","doi-asserted-by":"crossref","DOI":"10.1101\/mcs.a003285","article-title":"Whole-genome sequencing in a family with twin boys with autism and intellectual disability suggests multimodal polygenic risk","volume":"4","author":"Mckenna","year":"2018","journal-title":"Mol. Case Stud."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0855","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/bpa.12415","article-title":"Primary olfactory cortex in autism and epilepsy: increased glial cells in autism","volume":"27","author":"Menassa","year":"2017","journal-title":"Brain Pathol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0860","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/nrg3405","article-title":"From promises to practical strategies in epigenetic epidemiology","volume":"14","author":"Mill","year":"2013","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0865","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/em.21722","article-title":"Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11-q13 duplication autism spectrum disorder","volume":"53","author":"Mitchell","year":"2012","journal-title":"Environ. Mol. Mutagen."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0870","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2202-12-81","article-title":"The protocadherins, PCDHB1 and PCDH7, are regulated by MeCP2 in neuronal cells and brain tissues: implication for pathogenesis of Rett syndrome","volume":"12","author":"Miyake","year":"2011","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0875","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.biopsych.2010.05.024","article-title":"Microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism","volume":"68","author":"Morgan","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0880","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.brainres.2012.03.036","article-title":"Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism","volume":"1456","author":"Morgan","year":"2012","journal-title":"Brain Res."},{"issue":"10","key":"10.1016\/j.neubiorev.2021.07.014_bib0885","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0110356","article-title":"Stereological study of amygdala glial populations in adolescents and adults with autism spectrum disorder","volume":"9","author":"Morgan","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.neubiorev.2021.07.014_bib0890","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0056927","article-title":"Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism","volume":"8","author":"Muratore","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0895","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.4161\/epi.1.4.3514","article-title":"Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation","volume":"1","author":"Nagarajan","year":"2006","journal-title":"Epigenetics"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0900","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/aur.24","article-title":"MECP2 promoter methylation and X chromosome inactivation in autism","volume":"1","author":"Nagarajan","year":"2008","journal-title":"Autism Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0905","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.pnpbp.2010.11.033","article-title":"Replication study of Japanese cohorts supports the role of STX1A in autism susceptibility","volume":"35","author":"Nakamura","year":"2011","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0910","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.1523\/JNEUROSCI.5057-11.2012","article-title":"Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation","volume":"32","author":"Nalavadi","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0915","doi-asserted-by":"crossref","first-page":"3036","DOI":"10.1096\/fj.10-154484","article-title":"Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain","volume":"24","author":"Nguyen","year":"2010","journal-title":"FASEB J."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0920","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40478-015-0184-4","article-title":"Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid","volume":"3","author":"Nicolini","year":"2015","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0925","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/aur.88","article-title":"Decreased GABA<inf>a<\/inf> receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism","volume":"2","author":"Oblak","year":"2009","journal-title":"Autism Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0930","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1002\/aur.188","article-title":"Altered posterior cingulate cortical cyctoarchitecture, but normal density of neurons and interneurons in the posterior cingulate cortex and fusiform gyrus in autism","volume":"4","author":"Oblak","year":"2011","journal-title":"Autism Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0935","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1002\/aur.1317","article-title":"Reduced serotonin receptor subtypes in a limbic and a neocortical region in autism","volume":"6","author":"Oblak","year":"2013","journal-title":"Autism Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0940","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1038\/mp.2014.124","article-title":"Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR","volume":"20","author":"Oguro-Ando","year":"2015","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0945","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1038\/nn.2207","article-title":"Functional organization of the transcriptome in human brain","volume":"11","author":"Oldham","year":"2008","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0950","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1038\/s41598-017-02152-x","article-title":"Disruption of melatonin synthesis is associated with impaired 14-3-3 and miR-451 levels in patients with autism spectrum disorders","volume":"7","author":"Pagan","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0955","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/mp.2008.63","article-title":"Altered calcium homeostasis in autism-spectrum disorders: evidence from biochemical and genetic studies of the mitochondrial aspartate\/glutamate carrier AGC1","volume":"15","author":"Palmieri","year":"2010","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0960","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/nature20612","article-title":"Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism","volume":"540","author":"Parikshak","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0965","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1007\/s12035-015-9178-2","article-title":"Altered mRNA levels of glucocorticoid receptor, mineralocorticoid receptor, and co-chaperones (FKBP5 and PTGES3) in the middle frontal gyrus of autism spectrum disorder subjects","volume":"53","author":"Patel","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0970","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.bbr.2012.12.062","article-title":"Heparan sulfate deficiency in autistic postmortem brain tissue from the subventricular zone of the lateral ventricles","volume":"243","author":"Pearson","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0975","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.neulet.2013.12.071","article-title":"The dual role of astrocyte activation and reactive gliosis","volume":"565","author":"Pekny","year":"2014","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0980","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1176\/appi.ajp.158.7.1058","article-title":"Cholinergic activity in autism: abnormalities in the cerebral cortex and basal forebrain","volume":"158","author":"Perry","year":"2001","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0985","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.neubiorev.2011.10.008","article-title":"A systematic review and meta-analysis of the fMRI investigation of autism spectrum disorders","volume":"36","author":"Philip","year":"2012","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0990","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2013.91","article-title":"Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome","volume":"3","author":"Plummer","year":"2013","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib0995","doi-asserted-by":"crossref","first-page":"20180944","DOI":"10.1259\/bjr.20180944","article-title":"Revisiting the excitation\/inhibition imbalance hypothesis of ASD through a clinical lens","volume":"92","author":"Port","year":"2019","journal-title":"Br. J. Radiol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1000","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1212\/WNL.57.9.1618","article-title":"Postmortem brain abnormalities of the glutamate neurotransmitter system in autism","volume":"57","author":"Purcell","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1005","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1023\/A:1010751232295","article-title":"Assessment of neural cell adhesion molecule (NCAM) in autistic serum and postmortem brain","volume":"31","author":"Purcell","year":"2001","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1010","series-title":"Handbook of Clinical Neurology","doi-asserted-by":"crossref","DOI":"10.1016\/B978-0-444-63233-3.00021-X","article-title":"Genetics of autism spectrum disorder","author":"Ramaswami","year":"2018"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biopsych.2005.03.026","article-title":"When is the brain enlarged in autism? A meta-analysis of all brain size reports","volume":"58","author":"Redcay","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1020","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/S2215-0366(15)00376-4","article-title":"Prevalence of autism spectrum disorder phenomenology in genetic disorders: a systematic review and meta-analysis","volume":"2","author":"Richards","year":"2015","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1025","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1098\/rstb.2006.2016","article-title":"Brain micro-ecologies: neural stem cell niches in the adult mammalian brain","volume":"363","author":"Riquelme","year":"2008","journal-title":"Philos. Trans. Biol. Sci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1030","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1034\/j.1601-183X.2003.00037.x","article-title":"Model of autism: increased ratio of excitation\/inhibition in key neural systems","volume":"2","author":"Rubenstein","year":"2003","journal-title":"Genes Brain Behav."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib1035","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-4-41","article-title":"Phosphorylated fragile X mental retardation protein at serine 499, is reduced in cerebellar vermis and superior frontal cortex of subjects with autism: implications for fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling","volume":"4","author":"Rustan","year":"2013","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1040","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.pscychresns.2015.08.016","article-title":"Head circumference and brain size in autism spectrum disorder: a systematic review and meta-analysis","volume":"234","author":"Sacco","year":"2015","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1045","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1007\/s12311-009-0105-9","article-title":"Increase in cerebellar neurotrophin-3 and oxidative stress markers in autism","volume":"8","author":"Sajdel-Sulkowska","year":"2009","journal-title":"Cerebellum"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1050","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s12311-010-0223-4","article-title":"Brain region-specific changes in oxidative stress and neurotrophin levels in autism spectrum disorders (ASD)","volume":"10","author":"Sajdel-Sulkowska","year":"2011","journal-title":"Cerebellum"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1055","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/nature10945","article-title":"De novo mutations revealed by whole-exome sequencing are strongly associated with autism","volume":"485","author":"Sanders","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1060","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.brainres.2010.08.067","article-title":"Von Economo neurons in autism: a stereologic study of the frontoinsular cortex in children","volume":"1380","author":"Santos","year":"2011","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib1065","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-4-14","article-title":"Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder","volume":"4","author":"Sarachana","year":"2013","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1070","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF02408436","article-title":"Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS)","volume":"10","author":"Schopler","year":"1980","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1075","doi-asserted-by":"crossref","first-page":"7674","DOI":"10.1523\/JNEUROSCI.1285-06.2006","article-title":"Stereological analysis of amygdala neuron number in autism","volume":"26","author":"Schumann","year":"2006","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib1080","doi-asserted-by":"crossref","DOI":"10.1186\/s13229-017-0117-0","article-title":"Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain","volume":"8","author":"Schumann","year":"2017","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1085","doi-asserted-by":"crossref","first-page":"3337","DOI":"10.1002\/hbm.23244","article-title":"Brain GABA levels across psychiatric disorders: a systematic literature review and meta\u2010analysis of 1H\u2010MRS studies","volume":"37","author":"Sch\u00fcr","year":"2016","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1090","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1038\/mp.2013.28","article-title":"Genes for endosomal NHE6 and NHE9 are misregulated in autism brains","volume":"19","author":"Schwede","year":"2014","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1095","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s11689-018-9237-x","article-title":"Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex","volume":"10","author":"Schwede","year":"2018","journal-title":"J. Neurodev. Disord."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib1100","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-2-19","article-title":"Increased copy number for methylated maternal 15q duplications leads to changes in gene and protein expression in human cortical samples","volume":"2","author":"Scoles","year":"2011","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1105","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.neuroscience.2009.10.035","article-title":"Cathepsin D and apoptosis related proteins are elevated in the brain of autistic subjects","volume":"165","author":"Sheikh","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1110","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1002\/jnr.22416","article-title":"BDNF\u2010Akt\u2010Bcl2 antiapoptotic signaling pathway is compromised in the brain of autistic subjects","volume":"88","author":"Sheikh","year":"2010","journal-title":"J. Neurosci. Res."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib1115","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-4-6","article-title":"Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism","volume":"4","author":"Shimmura","year":"2013","journal-title":"Mol. Autism"},{"issue":"11","key":"10.1016\/j.neubiorev.2021.07.014_bib1120","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0113712","article-title":"Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf\/J mouse model of autism and similarities with human post mortem cerebellum","volume":"9","author":"Shpyleva","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1125","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1001\/archgenpsychiatry.2011.151","article-title":"Epigenetic signatures of autism trimethylated H3K4 landscapes in prefrontal neurons","volume":"69","author":"Shulha","year":"2012","journal-title":"Arch. Gen. Psychiatry"},{"issue":"2","key":"10.1016\/j.neubiorev.2021.07.014_bib1130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0081255","article-title":"Regional alterations in Purkinje cell density in patients with autism","volume":"9","author":"Skefos","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1135","first-page":"41","article-title":"Structural and functional aberrations of the auditory brainstem in Autism Spectrum Disorder","volume":"119","author":"Smith","year":"2019","journal-title":"J. Am. Osteopath. Assoc."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1140","first-page":"1","article-title":"Widespread temporal coding of cognitive control in the human prefrontal cortex","author":"Smith","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1145","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0387-7604(87)80079-7","article-title":"Reduced concentrations of ascorbic acid and glutathione in a single case of Rett syndrome: a postmortem brain study","volume":"9","author":"Sofic","year":"1987","journal-title":"Brain Dev."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1150","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1002\/aur.1835","article-title":"Decreased parvalbumin mRNA levels in cerebellar Purkinje cells in autism","volume":"10","author":"Soghomonian","year":"2017","journal-title":"Autism Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1155","article-title":"Adult raphe-specific deletion of Lmx1b leads to central serotonin deficiency","volume":"6","author":"Song","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1160","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1177\/0883073815602067","article-title":"Specific regional and age-related small noncoding RNA expression patterns within superior temporal gyrus of typical human brains are less distinct in autism brains","volume":"30","author":"Stamova","year":"2015","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1165","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.eurpsy.2007.05.006","article-title":"Towards a neuroanatomy of autism: a systematic review and meta-analysis of structural magnetic resonance imaging studies","volume":"23","author":"Stanfield","year":"2008","journal-title":"Eur. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1170","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.neuron.2013.01.010","article-title":"Rare inherited variation in autism: beginning to see the forest and a few trees","volume":"77","author":"Stein","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1175","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1056\/NEJMoa1307491","article-title":"Patches of disorganization in the neocortex of children with autism","volume":"370","author":"Stoner","year":"2014","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib1180","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-2-14","article-title":"Decreased expression of axon-guidance receptors in the anterior cingulate cortex in autism","volume":"2","author":"Suda","year":"2011","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1185","doi-asserted-by":"crossref","first-page":"1385-+","DOI":"10.1016\/j.cell.2016.10.031","article-title":"Histone acetylome-wide association study of Autism Spectrum Disorder","volume":"167","author":"Sun","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1190","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/ng0994-52","article-title":"Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region","volume":"8","author":"Sutcliffe","year":"1994","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1195","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1093\/hmg\/ddn380","article-title":"Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism","volume":"18","author":"Swanberg","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1200","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.nbd.2013.01.006","article-title":"Mitochondrial abnormalities in temporal lobe of autistic brain","volume":"54","author":"Tang","year":"2013","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1205","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.neuron.2014.07.040","article-title":"Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits","volume":"83","author":"Tang","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1210","doi-asserted-by":"crossref","first-page":"180138","DOI":"10.1098\/rsob.180138","article-title":"Synaptic dysfunction in neurodegenerative and neurodevelopmental diseases: an overview of induced pluripotent stem-cell-based disease models","volume":"8","author":"Taoufik","year":"2018","journal-title":"Open Biol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1215","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1124\/jpet.104.082420","article-title":"Transcriptional and translational regulation of glial activation by morphine in a rodent model of neuropathic pain","volume":"313","author":"Tawfik","year":"2005","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1220","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1007\/s10803-012-1513-0","article-title":"Microglia in the cerebral cortex in autism","volume":"42","author":"Tetreault","year":"2012","journal-title":"J. Autism Dev. Disord."},{"issue":"8","key":"10.1016\/j.neubiorev.2021.07.014_bib1225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0023738","article-title":"Association of transcription factor gene LMX1B with autism","volume":"6","author":"Thanseem","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1230","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.biopsych.2011.09.020","article-title":"Elevated transcription factor specificity protein 1 in autistic brains alters the expression of autism candidate genes","volume":"71","author":"Thanseem","year":"2012","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1235","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1080\/08830180903093796","article-title":"miR-155: on the crosstalk between inflammation and cancer","volume":"28","author":"Tili","year":"2009","journal-title":"Int. Rev. Immunol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1240","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.55684","article-title":"Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women","volume":"9","author":"Trakoshis","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1245","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/s41593-018-0287-x","article-title":"Widespread RNA editing dysregulation in brains from autistic individuals","volume":"22","author":"Tran","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1250","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.biopsych.2017.09.029","article-title":"Cerebellar volume in autism: literature meta-analysis and analysis of the autism brain imaging data exchange cohort","volume":"83","author":"Traut","year":"2017","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1255","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s40478-019-0684-8","article-title":"Postnatal development and maturation of layer 1 in the lateral prefrontal cortex and its disruption in autism","volume":"7","author":"Trutzer","year":"2019","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1260","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/ng1562","article-title":"Fine-scale structural variation of the human genome","volume":"37","author":"Tuzun","year":"2005","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1265","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1097\/NEN.0000000000000108","article-title":"Neuropathology of the anterior midcingulate cortex in young children with autism","volume":"73","author":"Uppal","year":"2014","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1270","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1093\/brain\/awn033","article-title":"Neurons in the fusiform gyrus are fewer and smaller in autism","volume":"131","author":"Van Kooten","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1275","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/ana.20315","article-title":"Neuroglial activation and neuroinflammation in the brain of patients with autism","volume":"57","author":"Vargas","year":"2005","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1280","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s00401-017-1736-4","article-title":"Autism spectrum disorder: neuropathology and animal models","volume":"134","author":"Varghese","year":"2017","journal-title":"Acta Neuropathol."},{"issue":"1","key":"10.1016\/j.neubiorev.2021.07.014_bib1285","doi-asserted-by":"crossref","DOI":"10.1186\/2040-2392-4-32","article-title":"Expression of non-protein-coding antisense RNAs in genomic regions related to autism spectrum disorders","volume":"4","author":"Velmeshev","year":"2013","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1290","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/nature10110","article-title":"Transcriptomic analysis of autistic brain reveals convergent molecular pathology","volume":"474","author":"Voineagu","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1295","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.neuron.2014.07.016","article-title":"The cerebellum, sensitive periods, and autism","volume":"83","author":"Wang","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1300","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/2051-5960-2-28","article-title":"Brain-region-specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism","volume":"2","author":"Wegiel","year":"2014","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1305","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ijdevneu.2014.04.004","article-title":"The apoptotic perspective of autism","volume":"36","author":"Wei","year":"2014","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1310","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/ng.3863","article-title":"Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders","volume":"49","author":"Weiner","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1315","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1002\/cne.24332","article-title":"Protracted dendritic growth in the typically developing human amygdala and increased spine density in young ASD brains","volume":"526","author":"Weir","year":"2018","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1320","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0165-3806(93)90084-N","article-title":"Neurochemical alterations in Rett syndrome","volume":"74","author":"Wenk","year":"1993","journal-title":"Dev. Brain Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1325","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms10717","article-title":"Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders","volume":"7","author":"Werling","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1330","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1002\/jnr.22056","article-title":"Density of cerebellar basket and stellate cells in autism: evidence for a late developmental loss of Purkinje cells","volume":"87","author":"Whitney","year":"2009","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1335","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.expneurol.2018.05.019","article-title":"Are dopamine receptor and transporter changes in Rett syndrome reflected in Mecp2-deficient mice?","volume":"307","author":"Wong","year":"2018","journal-title":"Exp. Neurol."},{"issue":"Supplement 3","key":"10.1016\/j.neubiorev.2021.07.014_bib1340","doi-asserted-by":"crossref","first-page":"S983","DOI":"10.1016\/j.euroneuro.2017.08.359","article-title":"Convergent methylomic signatures between autism associated with duplications of chromosome 15q and idiopathic autism","volume":"29","author":"Wong","year":"2019","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1345","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1093\/hmg\/ddz052","article-title":"Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue","volume":"28","author":"Wong","year":"2019","journal-title":"Hum. Mol. Genet."},{"issue":"5","key":"10.1016\/j.neubiorev.2021.07.014_bib1350","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2017.87","article-title":"Altered expression of histamine signaling genes in autism spectrum disorder","volume":"7","author":"Wright","year":"2017","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1355","doi-asserted-by":"crossref","first-page":"386","DOI":"10.2350\/13-11-1399-CR.1","article-title":"Neuropathology of 22q11 deletion syndrome in an infant","volume":"17","author":"Wu","year":"2014","journal-title":"Pediatr. Dev. Pathol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1360","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1038\/nn.4373","article-title":"Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder","volume":"19","author":"Wu","year":"2016","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1365","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1038\/mp.2013.146","article-title":"Common genetic variants in 1p13.2 associate with risk of autism","volume":"19","author":"Xia","year":"2014","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1370","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s00401-006-0176-3","article-title":"Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications","volume":"113","author":"Yip","year":"2007","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1375","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/aur.62","article-title":"Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study","volume":"2","author":"Yip","year":"2009","journal-title":"Autism Res."},{"issue":"May","key":"10.1016\/j.neubiorev.2021.07.014_bib1380","article-title":"Aberrant NF-kappaB expression in autism spectrum condition: a mechanism for neuroinflammation","volume":"2","author":"Young","year":"2011","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1385","first-page":"19","article-title":"Decreased brain levels of vitamin B12 in aging, autism and schizophrenia","volume":"11","author":"Zhang","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1390","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1008043","article-title":"Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals","volume":"15","author":"Zhao","year":"2019","journal-title":"PLoS Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1395","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1093\/hmg\/ddt547","article-title":"Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders","volume":"23","author":"Zhu","year":"2014","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1400","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2013.123","article-title":"Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum","volume":"4","author":"Zhubi","year":"2014","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1405","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/s12031-012-9880-8","article-title":"Aberrant expression of long noncoding rnas in autistic brain","volume":"49","author":"Ziats","year":"2013","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1410","doi-asserted-by":"crossref","first-page":"14595","DOI":"10.1523\/JNEUROSCI.2257-10.2010","article-title":"Changes in prefrontal axons may disrupt the network in autism","volume":"30","author":"Zikopoulos","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1415","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3389\/fnhum.2013.00609","article-title":"Altered neural connectivity in excitatory and inhibitory cortical circuits in autism","volume":"7","author":"Zikopoulos","year":"2013","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.neubiorev.2021.07.014_bib1420","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1007\/s00401-018-1904-1","article-title":"Opposite development of short- and long-range anterior cingulate pathways in autism","volume":"136","author":"Zikopoulos","year":"2018","journal-title":"Acta Neuropathol."}],"container-title":["Neuroscience &amp; Biobehavioral Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763421003134?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763421003134?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T16:02:42Z","timestamp":1744992162000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0149763421003134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":284,"alternative-id":["S0149763421003134"],"URL":"https:\/\/doi.org\/10.1016\/j.neubiorev.2021.07.014","relation":{},"ISSN":["0149-7634"],"issn-type":[{"value":"0149-7634","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders","name":"articletitle","label":"Article Title"},{"value":"Neuroscience & Biobehavioral Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neubiorev.2021.07.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}