{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T19:49:33Z","timestamp":1785786573859,"version":"3.56.0"},"reference-count":353,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience &amp; Biobehavioral Reviews"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.neubiorev.2023.105169","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T11:26:53Z","timestamp":1681298813000},"page":"105169","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Insulin and disorders of behavioural flexibility"],"prefix":"10.1016","volume":"150","author":[{"given":"Mair\u00e9ad","family":"Sullivan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Fernandez-Aranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00eda","family":"Camacho-Barcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Harkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Macr\u00ec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernat","family":"Mora-Maltas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Jim\u00e9nez-Murcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aet","family":"O'Leary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Maria","family":"Ottomana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Presta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Slattery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Scholtz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey C.","family":"Glennon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neubiorev.2023.105169_bib1","doi-asserted-by":"crossref","unstructured":"Abbott M.-A., Wells D.G., Fallon J.R. The Insulin Receptor Tyrosine Kinase Substrate p58\/53 and the Insulin Receptor Are Components of CNS Synapses. 1999.","DOI":"10.1523\/JNEUROSCI.19-17-07300.1999"},{"key":"10.1016\/j.neubiorev.2023.105169_bib2","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1017\/S1461145705005055","article-title":"Patients with obsessive-compulsive disorder have increased 5-HT 2A receptor binding in the caudate nuclei","volume":"8","author":"Adams","year":"2005","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib3","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1126\/science.1234733","article-title":"Repeated cortico-striatal stimulation generates persistent OCD-like behavior","volume":"340","author":"Ahmari","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.neubiorev.2023.105169_bib4","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1038\/npp.2015.26","article-title":"Astroglial glutamate transporter deficiency increases synaptic excitability and leads to pathological repetitive behaviors in mice","volume":"40","author":"Aida","year":"2015","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib5","first-page":"383","article-title":"Inflammation and Alzheimer\u2019s disease","volume":"21","author":"Akiyama","year":"2000"},{"key":"10.1016\/j.neubiorev.2023.105169_bib6","doi-asserted-by":"crossref","first-page":"5562","DOI":"10.1073\/pnas.91.12.5562","article-title":"Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease","volume":"91","author":"Alonso","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2012.00046","article-title":"Imaging-genetics in autism spectrum disorder: advances, translational impact, and future directions","volume":"3","author":"Ameis","year":"2012","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib8","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1093\/brain\/awh045","article-title":"Inhibitory functioning in Alzheimer\u2019s disease","volume":"127","author":"Amieva","year":"2004","journal-title":"Brain"},{"key":"10.1016\/j.neubiorev.2023.105169_bib9","unstructured":"Anon, Tissue expression of INSR - Summary - The Human Protein Atlas [Online]. [date unknown]. \u3008https:\/\/www.proteinatlas.org\/ENSG00000171105-INSR\/tissue\u3009 [25 Nov. 2020a]."},{"key":"10.1016\/j.neubiorev.2023.105169_bib10","unstructured":"Anon, Final Report Summary - TACTICS (Translational Adolescent and Childhood Therapeutic Interventions in Compulsive Syndromes) | Report Summary | TACTICS | FP7 | CORDIS | European Commission [Online]. [date unknown]. \u3008https:\/\/cordis.europa.eu\/project\/id\/278948\/reporting\/de\u3009 [4 Dec. 2020a]."},{"key":"10.1016\/j.neubiorev.2023.105169_bib11","unstructured":"Anon, Tissue expression of IGF1R - Summary - The Human Protein Atlas [Online]. [date unknown]. \u3008https:\/\/www.proteinatlas.org\/ENSG00000140443-IGF1R\/tissue\u3009 [25 Nov. 2020a]."},{"key":"10.1016\/j.neubiorev.2023.105169_bib12","unstructured":"Anon, Clinical Definition (DSM-5) of Obsessive Compulsive Disorder (OCD) [Online]. [date unknown]. \u3008https:\/\/beyondocd.org\/information-for-individuals\/clinical-definition-of-ocd\u3009 [21 Oct. 2020b]."},{"key":"10.1016\/j.neubiorev.2023.105169_bib13","unstructured":"Anon, Limbic System: Hippocampus (Section 4, Chapter 5) Neuroscience Online: An Electronic Textbook for the Neurosciences | Department of Neurobiology and Anatomy - The University of Texas Medical School at Houston [Online]. [date unknown]. \u3008https:\/\/nba.uth.tmc.edu\/neuroscience\/m\/s4\/chapter05.html\u3009 [4 Feb. 2021]."},{"key":"10.1016\/j.neubiorev.2023.105169_bib14","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.73138","article-title":"Type 2 diabetes mellitus accelerates brain aging and cognitive decline: complementary findings from UK Biobank and meta-analyses","volume":"11","author":"Antal","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.neubiorev.2023.105169_bib15","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1038\/oby.2011.57","article-title":"Inhibiting food reward: delay discounting, food reward sensitivity, and palatable food intake in overweight and obese women","volume":"19","author":"Appelhans","year":"2011","journal-title":"Obesity"},{"key":"10.1016\/j.neubiorev.2023.105169_bib16","series-title":"Nat. Rev. Neurol","first-page":"168","article-title":"Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums","author":"Arnold","year":"2018"},{"key":"10.1016\/j.neubiorev.2023.105169_bib17","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.neuron.2016.12.020","article-title":"GLUT4 mobilization supports energetic demands of active synapses","volume":"93","author":"Ashrafi","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib18","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.bbi.2010.08.003","article-title":"Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome","volume":"25","author":"Ashwood","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.neubiorev.2023.105169_bib19","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1001\/jamapsychiatry.2017.1567","article-title":"Inflammation in the neurocircuitry of obsessive-compulsive disorder","volume":"74","author":"Attwells","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib20","series-title":"J. Neurol","first-page":"1497","article-title":"Intranasal insulin in Alzheimer\u2019s dementia or mild cognitive impairment: a systematic review","author":"Avgerinos","year":"2018"},{"key":"10.1016\/j.neubiorev.2023.105169_bib21","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1172\/JCI68295","article-title":"Exenatide and the treatment of patients with Parkinson\u2019sdisease","volume":"123","author":"Aviles-Olmos","year":"2013","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neubiorev.2023.105169_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0247753","article-title":"Acute hyperglycaemia leads to altered frontal lobe brain activity and reduced working memory in type 2 diabetes","volume":"16","author":"Backestr\u00f6m","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2023.105169_bib23","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.neubiorev.2016.03.005","article-title":"Diabetes and Alzheimer\u2019s disease crosstalk","volume":"64","author":"Baglietto-Vargas","year":"2016","journal-title":"Neurosci. Biobehav Rev."},{"key":"10.1016\/j.neubiorev.2023.105169_bib24","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.parkreldis.2017.01.017","article-title":"Personality and addictive behaviours in early Parkinson\u2019s disease and REM sleep behaviour disorder","volume":"37","author":"Baig","year":"2017","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.neubiorev.2023.105169_bib25","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1001\/archneurol.2010.225","article-title":"Insulin resistance and alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes","volume":"68","author":"Baker","year":"2011","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib26","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/s41586-020-2704-z","article-title":"Value-guided remapping of sensory cortex by lateral orbitofrontal cortex","volume":"585","author":"Banerjee","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2023.105169_bib27","series-title":"Pharmacol. Ther","first-page":"82","article-title":"Insulin in the brain: there and back again","author":"Banks","year":"2012"},{"key":"10.1016\/j.neubiorev.2023.105169_bib28","doi-asserted-by":"crossref","first-page":"610","DOI":"10.2174\/1570159X14666160229114755","article-title":"Mitochondrial dysfunction in depression","volume":"14","author":"Bansal","year":"2016","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib29","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1001\/jama.2021.4001","article-title":"Association between age at diabetes onset and subsequent risk of dementia","volume":"325","author":"Barbiellini Amidei","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib30","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/0896-6273(95)90216-3","article-title":"Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons","volume":"14","author":"Beck","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib31","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.pbb.2010.04.016","article-title":"Dopamine and binge eating behaviors","volume":"97","author":"Bello","year":"2010","journal-title":"Pharm. Biochem Behav."},{"key":"10.1016\/j.neubiorev.2023.105169_bib32","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.neuron.2007.08.004","article-title":"Expectation modulates neural responses to pleasant and aversive stimuli in primate amygdala","volume":"55","author":"Belova","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2018.10.018","article-title":"Neuroendocrinology of reward in anorexia nervosa and bulimia nervosa: beyond leptin and ghrelin","volume":"497","author":"Berner","year":"2019","journal-title":"Mol. Cell Endocrinol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib34","doi-asserted-by":"crossref","first-page":"5671","DOI":"10.1523\/JNEUROSCI.1039-08.2008","article-title":"Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol","volume":"28","author":"Bertran-Gonzalez","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib35","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bbr.2013.04.037","article-title":"Neural structures underlying set-shifting: roles of medial prefrontal cortex and anterior cingulate cortex","volume":"250","author":"Bissonette","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neubiorev.2023.105169_bib36","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2014.00161","article-title":"Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer\u2019s disease","volume":"5","author":"Bl\u00e1zquez","year":"2014","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib37","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1176\/appi.ajp.2008.08020320","article-title":"Reviews and overviews meta-analysis of the symptom structure of obsessive-compulsive disorder","volume":"165","author":"Bloch","year":"2008","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib38","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1176\/appi.ajp.2016.16020201","article-title":"Distinct subcortical volume alterations in pediatric and adult OCD: a worldwide meta- and mega-analysis","volume":"174","author":"Boedhoe","year":"2017","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib39","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1176\/appi.ajp.2016.16020201","article-title":"Distinct subcortical volume alterations in pediatric and adult OCD: A worldwide meta- and mega-analysis","volume":"174","author":"Boedhoe","year":"2017","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib40","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1111\/j.1471-4159.2005.03485.x","article-title":"The activation of 5-HT2A receptors in prefrontal cortex enhances dopaminergic activity","volume":"95","author":"Bortolozzi","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neubiorev.2023.105169_bib41","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/s41398-020-0793-y","article-title":"Shared genetic etiology between obsessive-compulsive disorder, obsessive-compulsive symptoms in the population, and insulin signaling","volume":"10","author":"Bralten","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib42","doi-asserted-by":"crossref","unstructured":"Breteler M.M.B., Vermeer S.E., Den Heijer T., Koudstaal P.J., Oudkerk M., Hofman A. Scan Study Incidence and Risk Factors of Silent Brain Infarcts in the Population-Based Rotterdam. 34: 392\u2013396, 2003. doi: 10.1161\/01.STR.0000052631.98405.15.","DOI":"10.1161\/01.STR.0000052631.98405.15"},{"key":"10.1016\/j.neubiorev.2023.105169_bib43","doi-asserted-by":"crossref","first-page":"E63","DOI":"10.1152\/ajpendo.00115.2014","article-title":"P38 mapk activation upregulates proinflammatory pathways in skeletal muscle cells from insulin-resistant type 2 diabetic patients","volume":"308","author":"Brown","year":"2015","journal-title":"Am. J. Physiol. - Endocrinol. Metab."},{"key":"10.1016\/j.neubiorev.2023.105169_bib44","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1203\/01.PDR.0000156369.62787.96","article-title":"Early developmental changes in IGF-I, IGF-II, IGF binding protein-1, and IGF binding protein-3 concentration in the cerebrospinal fluid of children","volume":"58","author":"Bunn","year":"2005","journal-title":"Pedia Res"},{"key":"10.1016\/j.neubiorev.2023.105169_bib45","series-title":"Nat. Rev. Neurosci","first-page":"148","article-title":"Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease","author":"Butterfield","year":"2019"},{"key":"10.1016\/j.neubiorev.2023.105169_bib46","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/erv.2591","article-title":"Perfectionism and cognitive rigidity in anorexia nervosa: Is there an association","volume":"26","author":"Buzzichelli","year":"2018","journal-title":"Eur. Eat. Disord. Rev."},{"key":"10.1016\/j.neubiorev.2023.105169_bib47","doi-asserted-by":"crossref","first-page":"2914","DOI":"10.1172\/JCI99366","article-title":"Insulin regulates astrocyte gliotransmission and modulates behavior","volume":"128","author":"Cai","year":"2018","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neubiorev.2023.105169_bib48","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms14892","article-title":"Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression","volume":"8","author":"Cai","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neubiorev.2023.105169_bib49","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1038\/nn.4101","article-title":"Resolving the neural circuits of anxiety","volume":"18","author":"Calhoon","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib50","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2019.00319","article-title":"Altered cortico-striatal functional connectivity during resting state in obsessive-compulsive disorder","volume":"10","author":"Calz\u00e0","year":"2019","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib51","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1046\/j.1471-4159.2002.00892.x","article-title":"3-kinase regulation of dopamine uptake","volume":"81","author":"Carvelli","year":"2002","journal-title":"J. Neurochem"},{"key":"10.1016\/j.neubiorev.2023.105169_bib52","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1002\/hbm.23952","article-title":"The morphometric co-atrophy networking of schizophrenia, autistic and obsessive spectrum disorders","volume":"39","author":"Cauda","year":"2018","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neubiorev.2023.105169_bib53","doi-asserted-by":"crossref","DOI":"10.1111\/adb.13165","article-title":"Metformin in nucleus accumbens core reduces cue\u2010induced cocaine seeking in male and female rats","volume":"27","author":"Chan","year":"2022","journal-title":"Addict. Biol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib54","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nature09582","article-title":"Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes","volume":"468","author":"Chao","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2023.105169_bib55","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1038\/pr.2013.5","article-title":"Association of attention-deficit\/hyperactivity disorder with diabetes: a population-based study","volume":"73","author":"Chen","year":"2013","journal-title":"Pedia Res."},{"key":"10.1016\/j.neubiorev.2023.105169_bib56","doi-asserted-by":"crossref","DOI":"10.1186\/s12974-020-01853-x","article-title":"TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K\/Akt pathway after intracerebral hemorrhage in mice","volume":"17","author":"Chen","year":"2020","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.neubiorev.2023.105169_bib57","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1017\/S0033291715002238","article-title":"Deficits in executive functions among youths with autism spectrum disorders:an age-stratified analysis","volume":"46","author":"Chen","year":"2016","journal-title":"Psychol. Med."},{"key":"10.1016\/j.neubiorev.2023.105169_bib58","first-page":"1265","article-title":"Volume changes of cortical and subcortical reward circuitry in the brain of patients with type 2 diabetes mellitus","volume":"33","author":"Chen","year":"2013","journal-title":"Nan Fang. Yi Ke Da Xue Xue Bao"},{"key":"10.1016\/j.neubiorev.2023.105169_bib59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jnr.10634","article-title":"Insulin-like growth factor 1 is essential for normal dendritic growth","volume":"73","author":"Cheng","year":"2003","journal-title":"J. Neurosci. Res"},{"key":"10.1016\/j.neubiorev.2023.105169_bib60","first-page":"775","article-title":"The association between type 2 diabetes mellitus and Parkinson\u2019s disease","volume":"10","author":"Cheong","year":"2020","journal-title":"J. Park. Dis."},{"key":"10.1016\/j.neubiorev.2023.105169_bib61","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1002\/hbm.22390","article-title":"Plasma tau as a window to the brain\u2014negative associations with brain volume and memory function in mild cognitive impairment and early alzheimer\u2019s disease","volume":"35","author":"Chiu","year":"2014","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neubiorev.2023.105169_bib62","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.neuron.2008.04.014","article-title":"Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo","volume":"58","author":"Chiu","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib63","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0031-9384(03)00047-7","article-title":"Compulsive behavior in the 5-HT2C receptor knockout mouse","volume":"78","author":"Chou-Green","year":"2003","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neubiorev.2023.105169_bib64","doi-asserted-by":"crossref","first-page":"2884","DOI":"10.1093\/cercor\/bhs266","article-title":"The role of the anterior cingulate cortex in choices based on reward value and reward contingency","volume":"23","author":"Chudasama","year":"2013","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neubiorev.2023.105169_bib65","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/j.1471-4159.1986.tb00686.x","article-title":"Insulin is released from rat brain neuronal cells in culture","volume":"47","author":"Clarke","year":"1986","journal-title":"J. Neurochem"},{"key":"10.1016\/j.neubiorev.2023.105169_bib66","first-page":"888","article-title":"Reduced hippocampal functional connectivity during episodic memory retrieval in autism","volume":"27","author":"Cooper","year":"2017","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neubiorev.2023.105169_bib67","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrn755","article-title":"Control of goal-directed and stimulus-driven attention in the brain","volume":"3","author":"Corbetta","year":"2002","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib68","first-page":"293","volume":"14","author":"Crawley","year":"2012","journal-title":"Translational animal models of autism and neurodevelopmental disorders"},{"key":"10.1016\/j.neubiorev.2023.105169_bib69","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3389\/fpsyt.2016.00020","article-title":"Cortico-cerebellar connectivity in Autism Spectrum Disorder: what do we know so far?","volume":"7","author":"Crippa","year":"2016","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib70","series-title":"Trends Immunol","first-page":"4","article-title":"Inflammation: The link between insulin resistance, obesity and diabetes","author":"Dandona","year":"2004"},{"key":"10.1016\/j.neubiorev.2023.105169_bib71","series-title":"Mol. Neurobiol","first-page":"390","article-title":"Amelioration of diabetes-induced cognitive deficits by GSK-3\u03b2 inhibition is attributed to modulation of neurotransmitters and neuroinflammation","author":"Datusalia","year":"2014"},{"key":"10.1016\/j.neubiorev.2023.105169_bib72","doi-asserted-by":"crossref","first-page":"496","DOI":"10.2337\/diabetes.55.02.06.db05-1064","article-title":"Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase","volume":"55","author":"Davis","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.neubiorev.2023.105169_bib73","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.appet.2009.11.002","article-title":"Immediate pleasures and future consequences. A neuropsychological study of binge eating and obesity","volume":"54","author":"Davis","year":"2010","journal-title":"Appetite"},{"key":"10.1016\/j.neubiorev.2023.105169_bib74","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2015.00047","article-title":"Attention-deficit\/hyperactivity disorder in relation to addictive behaviors: a moderated-mediation analysis of personality-risk factors and sex","volume":"6","author":"Davis","year":"2015","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib75","series-title":"Neuropharmacology","first-page":"1123","article-title":"Insulin signaling and addiction","author":"Daws","year":"2011"},{"key":"10.1016\/j.neubiorev.2023.105169_bib76","series-title":"Neuroscientist","first-page":"148","article-title":"The nucleus accumbens and pavlovian reward learning","author":"Day","year":"2007"},{"key":"10.1016\/j.neubiorev.2023.105169_bib77","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.physbeh.2012.02.026","article-title":"The gut-brain dopamine axis: a regulatory system for caloric intake","volume":"106","author":"De Araujo","year":"2012","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neubiorev.2023.105169_bib78","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1212\/WNL.0000000000005771","article-title":"Association between diabetes and subsequent Parkinson disease: a record-linkage cohort study","volume":"91","author":"De Pablo-Fernandez","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib79","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1503\/jpn.140327","article-title":"An integrated molecular landscape implicates the regulation of dendritic spine formation through insulin-related signalling in obsessive\u2013compulsive disorder","volume":"41","author":"van de Vondervoort","year":"2016","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib80","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/s41398-019-0559-6","article-title":"Converging evidence points towards a role of insulin signaling in regulating compulsive behavior","volume":"9","author":"van de Vondervoort","year":"2019","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib81","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1056\/NEJM199508313330902","article-title":"Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus","volume":"333","author":"DeFronzo","year":"1995","journal-title":"New Engl. J. Med"},{"key":"10.1016\/j.neubiorev.2023.105169_bib82","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/2040-2392-3-7","article-title":"Social and monetary reward processing in autism spectrum disorders","volume":"3","author":"Delmonte","year":"2012","journal-title":"Mol. Autism"},{"key":"10.1016\/j.neubiorev.2023.105169_bib83","first-page":"1","article-title":"The neuropathological diagnosis of Alzheimer\u2019s disease","volume":"14","author":"Deture","year":"2019","journal-title":"Mol. Neurodegener. 2019 141"},{"key":"10.1016\/j.neubiorev.2023.105169_bib84","doi-asserted-by":"crossref","unstructured":"Devaskarss S.U., Giddingsn S.J., Rajakumars P.A., Carnaghin L.R., Menonll R.K., Zahm D.S. Insulin Gene Expression and Insulin Synthesis in Mammalian\u2019 Neuronal Cells*. 1994.","DOI":"10.1016\/S0021-9258(17)37214-9"},{"key":"10.1016\/j.neubiorev.2023.105169_bib85","doi-asserted-by":"crossref","first-page":"5274","DOI":"10.1073\/pnas.85.14.5274","article-title":"Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats","volume":"85","author":"Di Chiara","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib86","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.nlm.2010.05.010","article-title":"Behavioral flexibility in a mouse model of developmental cerebellar Purkinje cell loss","volume":"94","author":"Dickson","year":"2010","journal-title":"Neurobiol. Learn Mem."},{"key":"10.1016\/j.neubiorev.2023.105169_bib87","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.3389\/fimmu.2017.01088","article-title":"FOXO1 regulates bacteria-induced neutrophil activity","volume":"0","author":"Dong","year":"2017","journal-title":"Front Immunol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib88","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1093\/scan\/nsz085","article-title":"A review of the relationship between eating behavior, obesity and functional brain network organization","volume":"15","author":"Donofry","year":"2020","journal-title":"Soc. Cogn. Affect Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib89","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/S0065-1281(82)80080-9","article-title":"C-peptide immunoreactive neurons in human brain","volume":"70","author":"Dorn","year":"1982","journal-title":"Acta Histochem"},{"key":"10.1016\/j.neubiorev.2023.105169_bib90","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.diabres.2008.08.020","article-title":"Investigation on the relationship between diabetes mellitus type 2 and cognitive impairment","volume":"82","author":"Ebady","year":"2008","journal-title":"Diabetes Res Clin. Pr."},{"key":"10.1016\/j.neubiorev.2023.105169_bib91","doi-asserted-by":"crossref","first-page":"15253","DOI":"10.1073\/pnas.2002509117","article-title":"Brain networks underlying vulnerability and resilience to drug addiction","volume":"117","author":"Ersche","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib92","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1503\/jpn.190156","article-title":"Volumetric brain differences in clinical depression in association with anxiety: a systematic review with meta-analysis","volume":"45","author":"Espinoza Oyarce","year":"2020","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib93","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0306-4522(91)90145-E","article-title":"The basolateral amygdala-ventral striatal system and conditioned place preference: Further evidence of limbic-striatal interactions underlying reward-related processes","volume":"42","author":"Everitt","year":"1991","journal-title":"Neuroscience"},{"key":"10.1016\/j.neubiorev.2023.105169_bib94","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1038\/emboj.2010.268","article-title":"FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages","volume":"29","author":"Fan","year":"2010","journal-title":"EMBO J."},{"key":"10.1016\/j.neubiorev.2023.105169_bib95","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.nlm.2017.11.014","article-title":"Functional connectivity between anterior cingulate cortex and orbitofrontal cortex during value-based decision making","volume":"147","author":"Fatahi","year":"2018","journal-title":"Neurobiol. Learn Mem."},{"key":"10.1016\/j.neubiorev.2023.105169_bib96","doi-asserted-by":"crossref","first-page":"7267","DOI":"10.1523\/JNEUROSCI.17-19-07267.1997","article-title":"Conduction in segmentally demyelinated mammalian central axons","volume":"17","author":"Felts","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib97","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1017\/S146114570800847X","article-title":"The role of 5-HT2A and 5-HT2C receptors in the signal attenuation rat model of obsessive-compulsive disorder","volume":"11","author":"Flaisher-Grinberg","year":"2008","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib98","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2021.110395","article-title":"Executive function in obesity and anorexia nervosa: Opposite ends of a spectrum of disordered feeding behaviour","volume":"111","author":"Foldi","year":"2021","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib99","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/0026-0495(93)90275-S","article-title":"Insulin sensitivity, insulin secretion, and glucose effectiveness in anorexia nervosa: a minimal model analysis","volume":"42","author":"Fukushima","year":"1993","journal-title":"Metab. - Clin. Exp."},{"key":"10.1016\/j.neubiorev.2023.105169_bib100","series-title":"Neurosci. Biobehav. Rev","first-page":"16","article-title":"Fear extinction in the human brain: a meta-analysis of fMRI studies in healthy participants","author":"Fullana","year":"2018"},{"key":"10.1016\/j.neubiorev.2023.105169_bib101","first-page":"1","article-title":"Role of oligodendrocytes and myelin in the pathophysiology of autism spectrum disorder","author":"Galvez-Contreras","year":"2020","journal-title":"Brain Sci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib102","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2017.22","article-title":"Abnormal white matter structural connectivity in adults with obsessive-compulsive disorder","volume":"7","author":"Gan","year":"2017","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib103","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1146\/annurev-med-081117-041238","article-title":"Metformin for treatment of fragile X syndrome and other neurological disorders","volume":"70","author":"Gantois","year":"2019","journal-title":"Annu Rev. Med"},{"key":"10.1016\/j.neubiorev.2023.105169_bib104","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1124\/mol.104.009092","article-title":"Akt is essential for insulin modulation of amphetamine-induced human dopamine transporter cell-surface redistribution","volume":"68","author":"Garcia","year":"2005","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.neubiorev.2023.105169_bib105","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1023\/A:1018581407804","article-title":"Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: an electron microscopic study","volume":"26","author":"Garcia-Segura","year":"1997","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib106","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1750-1326-4-13","article-title":"The role of tau in neurodegeneration","volume":"4","author":"Gendron","year":"2009","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.neubiorev.2023.105169_bib107","article-title":"Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions","volume":"4","author":"Germel","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neubiorev.2023.105169_bib108","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1242\/jcs.056846","article-title":"MAPK\/Erk-dependent phosphorylation of synapsin mediates formation of functional synapses and short-term homosynaptic plasticity","volume":"123","author":"Giachello","year":"2010","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib109","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s00125-007-0602-7","article-title":"Hippocampal damage and memory impairments as possible early brain complications of type 2 diabetes","volume":"50","author":"Gold","year":"2007","journal-title":"Diabetologia"},{"key":"10.1016\/j.neubiorev.2023.105169_bib110","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1017\/S0033291717003464","article-title":"Impaired cognitive plasticity and goal-directed control in adolescent obsessive-compulsive disorder","volume":"48","author":"Gottwald","year":"2018","journal-title":"Psychol. Med"},{"key":"10.1016\/j.neubiorev.2023.105169_bib111","doi-asserted-by":"crossref","first-page":"757","DOI":"10.3233\/JAD-150587","article-title":"A TgCRND8 mouse model of Alzheimer\u2019s disease exhibits sexual dimorphisms in\u00a0behavioral indices of cognitive reserve","volume":"51","author":"Granger","year":"2016","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"10.1016\/j.neubiorev.2023.105169_bib112","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1159\/000487641","article-title":"Mutual relationship between tau and central insulin signalling: Consequences for ad and tauopathies?","author":"Gratuze","year":"2018","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib113","series-title":"Diabetes","first-page":"3992","article-title":"Insulin regulates brain function, but how does it get there","author":"Gray","year":"2014"},{"key":"10.1016\/j.neubiorev.2023.105169_bib114","doi-asserted-by":"crossref","unstructured":"Graybiel A.M., Rauch S.L. Toward a Neurobiology Review of Obsessive-Compulsive Disorder Dysfunction of the basal ganglia and associated cor. 2000.","DOI":"10.1016\/S0896-6273(00)00113-6"},{"key":"10.1016\/j.neubiorev.2023.105169_bib115","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.brainres.2009.08.005","article-title":"Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent","volume":"1296","author":"Grillo","year":"2009","journal-title":"Brain Res."},{"key":"10.1016\/j.neubiorev.2023.105169_bib116","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.neuron.2019.05.042","article-title":"Orbitofrontal circuits control multiple reinforcement-learning processes","volume":"103","author":"Groman","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib117","series-title":"Front. Cell. Neurosci","article-title":"Synaptopathology involved in autism spectrum disorder","author":"Guang","year":"2018"},{"key":"10.1016\/j.neubiorev.2023.105169_bib118","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2018.00437","article-title":"Executive functions in Alzheimer disease: a systematic review","volume":"10","author":"Guarino","year":"2019","journal-title":"Front Aging Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib119","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1016\/j.neuropsychologia.2006.01.014","article-title":"Decision-making in amnesia: do advantageous decisions require conscious knowledge of previous behavioural choices","volume":"44","author":"Gutbrod","year":"2006","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.neubiorev.2023.105169_bib120","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1038\/npp.2009.21","article-title":"Ventral striatal dopamine modulation of different forms of behavioral flexibility","volume":"34","author":"Haluk","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib121","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1007\/s10571-015-0268-5","article-title":"Insulin attenuates beta-amyloid-associated insulin\/akt\/eAAT signaling perturbations in human astrocytes","volume":"36","author":"Han","year":"2016","journal-title":"Cell Mol. Neurobiol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib122","doi-asserted-by":"crossref","first-page":"4521","DOI":"10.3892\/mmr.2017.7203","article-title":"Amyloid \u03b2-42 induces neuronal apoptosis by targeting mitochondria","volume":"16","author":"Han","year":"2017","journal-title":"Mol. Med Rep."},{"key":"10.1016\/j.neubiorev.2023.105169_bib123","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/S1474-4422(22)00395-7","article-title":"Diabetes and Alzheimer\u2019s disease: shared genetic susceptibility","volume":"21","author":"Hardy","year":"2022","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib124","first-page":"882","article-title":"PI3K signalling in inflammation","volume":"1851","author":"Hawkins","year":"2015"},{"key":"10.1016\/j.neubiorev.2023.105169_bib125","series-title":"Cells","article-title":"An immediate and long-term complication of COVID-19 may be type 2 diabetes mellitus: the central role of \u03b2-cell dysfunction, apoptosis and exploration of possible mechanisms","author":"Hayden","year":"2020"},{"key":"10.1016\/j.neubiorev.2023.105169_bib126","doi-asserted-by":"crossref","first-page":"3282","DOI":"10.1002\/hbm.25434","article-title":"Individual-based morphological brain network organization and its association with autistic symptoms in young children with autism spectrum disorder","volume":"42","author":"He","year":"2021","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neubiorev.2023.105169_bib127","first-page":"701","article-title":"Impaired insulin action in the human brain: causes and metabolic consequences","volume":"11","author":"Heni","year":"2015","journal-title":"Nat. Rev. Endocrinol. 2015 1112"},{"key":"10.1016\/j.neubiorev.2023.105169_bib128","series-title":"Cell. Signal","first-page":"2694","article-title":"The role of PI3K\/AKT\/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration","author":"Heras-Sandoval","year":"2014"},{"key":"10.1016\/j.neubiorev.2023.105169_bib129","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/hbm.24972","article-title":"An overview of the first 5\u2009years of the ENIGMA obsessive\u2013compulsive disorder working group: The power of worldwide collaboration","volume":"43","author":"Heuvel","year":"2022","journal-title":"Human Brain Mapping"},{"key":"10.1016\/j.neubiorev.2023.105169_bib130","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.baga.2018.10.002","article-title":"Autism, impulsivity and inhibition a review of the literature","volume":"14","author":"Hlavat\u00e1","year":"2018","journal-title":"Basal Ganglia"},{"key":"10.1016\/j.neubiorev.2023.105169_bib131","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1176\/appi.ajp.162.12.2269","article-title":"Is impaired set-shifting an endophenotype of anorexia nervosa?","volume":"162","author":"Holliday","year":"2005","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib132","doi-asserted-by":"crossref","first-page":"6398","DOI":"10.1073\/pnas.1803650115","article-title":"Human midcingulate cortex encodes distributed representations of task progress","volume":"115","author":"Holroyd","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib133","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1111\/j.1471-4159.2007.05194.x","article-title":"The GSK3 hypothesis of Alzheimer\u2019s disease","author":"Hooper","year":"2008","journal-title":"J. Neurochem. 104 J. Neurochem."},{"key":"10.1016\/j.neubiorev.2023.105169_bib134","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1083\/jcb.200308101","article-title":"IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes","volume":"164","author":"Hsieh","year":"2004","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib135","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1172\/JCI0214955","article-title":"Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes","volume":"109","author":"Hundal","year":"2002","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.neubiorev.2023.105169_bib136","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2202-4-10","article-title":"Insulin signaling inhibits the 5-HT2C receptor in choroid plexus via MAP kinase","volume":"4","author":"Hurley","year":"2003","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib137","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1002\/hbm.20887","article-title":"Neuroanatomical differences in brain areas implicated in perceptual and other core features of autism revealed by cortical thickness analysis and voxel\u2010based morphometry","volume":"31","author":"Hyde","year":"2010","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neubiorev.2023.105169_bib138","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/s41586-020-2115-1","article-title":"Dopamine D2 receptors in discrimination learning and spine enlargement","volume":"579","author":"Iino","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2023.105169_bib139","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2018.10.005","article-title":"The metabolic underpinning of eating disorders: a systematic review and meta-analysis of insulin sensitivity","volume":"497","author":"Ilyas","year":"2019","journal-title":"Mol. Cell Endocrinol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib140","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/0957154X9200301005","article-title":"Insulin treatment in psychiatry","volume":"3","author":"James","year":"1992","journal-title":"Hist. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib141","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1146\/annurev.biochem.73.011303.073706","article-title":"Cytochrome C-mediated apoptosis","author":"Jiang","year":"2004","journal-title":"Annu. Rev. Biochem. 73 Annu. Rev. Biochem."},{"key":"10.1016\/j.neubiorev.2023.105169_bib142","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.neuroimage.2009.12.047","article-title":"Predictive models of autism spectrum disorder based on brain regional cortical thickness","volume":"50","author":"Jiao","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.neubiorev.2023.105169_bib143","doi-asserted-by":"crossref","first-page":"3265","DOI":"10.1002\/jnr.21787","article-title":"Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer\u2019s disease and correction by insulin","volume":"86","author":"Jolivalt","year":"2008","journal-title":"J. Neurosci. Res"},{"key":"10.1016\/j.neubiorev.2023.105169_bib144","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4149\/endo_2014_01_35","article-title":"Glucose transport in brain-effect of inflammation","volume":"48","author":"Jurcovicova","year":"2014","journal-title":"Endocr. Regul."},{"key":"10.1016\/j.neubiorev.2023.105169_bib145","first-page":"1625","article-title":"The neural correlates of subjective value during intertemporal choice","volume":"10","author":"Kable","year":"2007","journal-title":"Nat. Neurosci. 2007 1012"},{"key":"10.1016\/j.neubiorev.2023.105169_bib146","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17040503","article-title":"Diabetes mellitus induces Alzheimer\u2019s disease pathology: histopathological evidence from animal models","volume":"17","author":"Kimura","year":"2016","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib147","doi-asserted-by":"crossref","first-page":"3463","DOI":"10.1073\/pnas.1500877112","article-title":"Insulin resistance in brain alters dopamine turnover and causes behavioral disorders","volume":"112","author":"Kleinridders","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib148","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jpsychires.2014.03.006","article-title":"Diffusion tensor imaging (DTI) studies in patients with obsessive-compulsive disorder (OCD): a review","volume":"54","author":"Koch","year":"2014","journal-title":"J. Psychiatr. Res"},{"key":"10.1016\/j.neubiorev.2023.105169_bib149","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13277","article-title":"Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus","volume":"20","author":"Kodali","year":"2021","journal-title":"Aging Cell"},{"key":"10.1016\/j.neubiorev.2023.105169_bib150","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.cmet.2011.03.021","article-title":"Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis","volume":"13","author":"K\u00f6nner","year":"2011","journal-title":"Cell Metab."},{"key":"10.1016\/j.neubiorev.2023.105169_bib151","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3109\/13651501.2012.697563","article-title":"The association of the metabolic profile in diabetes mellitus type 2 patients with obsessive-compulsive symptomatology and depressive symptomatology: new insights","volume":"17","author":"Kontoangelos","year":"2013","journal-title":"Int J. Psychiatry Clin. Pr."},{"key":"10.1016\/j.neubiorev.2023.105169_bib152","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jns.2013.06.019","article-title":"Diabetes mellitus and progression of vascular brain lesions and brain atrophy in patients with symptomatic atherosclerotic disease. the SMART-MR study","volume":"332","author":"Kooistra","year":"2013","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib153","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.pnpbp.2007.08.032","article-title":"Stereotypic behaviour in the deer mouse: pharmacological validation and relevance for obsessive compulsive disorder","volume":"32","author":"Korff","year":"2008","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib154","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.neulet.2018.02.022","article-title":"Insulin enhances GABAA receptor-mediated inhibitory currents in rat central amygdala neurons","volume":"671","author":"Korol","year":"2018","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neubiorev.2023.105169_bib155","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2019.01027","article-title":"Insulin protects cortical neurons against glutamate excitotoxicity","volume":"13","author":"Krasil\u2019nikova","year":"2019","journal-title":"Front Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib156","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0006696","article-title":"Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes","volume":"4","author":"Kring","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2023.105169_bib157","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.cellsig.2013.11.031","article-title":"High glucose driven expression of pro-inflammatory cytokine and chemokine genes in lymphocytes: molecular mechanisms of IL-17 family gene expression","volume":"26","author":"Kumar","year":"2014","journal-title":"Cell Signal"},{"key":"10.1016\/j.neubiorev.2023.105169_bib158","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1002\/emmm.201100177","article-title":"Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb","volume":"3","author":"Kuwabara","year":"2011","journal-title":"EMBO Mol. Med"},{"key":"10.1016\/j.neubiorev.2023.105169_bib159","doi-asserted-by":"crossref","DOI":"10.1038\/mtna.2015.35","article-title":"In vitro and in vivo modulation of alternative splicing by the biguanide metformin","volume":"4","author":"Laustriat","year":"2015","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"10.1016\/j.neubiorev.2023.105169_bib160","doi-asserted-by":"crossref","unstructured":"Leclerc M., Bourassa P., Tremblay C., Caron V., Sug\u00e8re C., Emond V., Bennett D.A., Calon F. Cerebrovascular insulin receptors are defective in Alzheimer\u2019s disease. 2023.","DOI":"10.1093\/brain\/awac309"},{"key":"10.1016\/j.neubiorev.2023.105169_bib161","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/j.neuropharm.2011.06.003","article-title":"Insulin promotes dendritic spine and synapse formation by the PI3K\/Akt\/mTOR and Rac1 signaling pathways","volume":"61","author":"Lee","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib162","doi-asserted-by":"crossref","first-page":"18543","DOI":"10.1074\/jbc.M414112200","article-title":"Insulin stimulates postsynaptic density-95 protein translation via the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway","volume":"280","author":"Lee","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neubiorev.2023.105169_bib163","series-title":"J. Endocrinol","first-page":"R67","article-title":"FoxO integration of insulin signaling with glucose and lipid metabolism","author":"Lee","year":"2017"},{"key":"10.1016\/j.neubiorev.2023.105169_bib164","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/mila.12172","article-title":"Obsessive\u2013compulsive disorder as a disorder of attention","volume":"33","author":"Levy","year":"2018","journal-title":"Mind Lang."},{"key":"10.1016\/j.neubiorev.2023.105169_bib165","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.pbb.2012.03.002","article-title":"Metformin attenuates Alzheimer\u2019s disease-like neuropathology in obese, leptin-resistant mice","volume":"101","author":"Li","year":"2012","journal-title":"Pharm. Biochem Behav."},{"key":"10.1016\/j.neubiorev.2023.105169_bib166","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/nature05292","article-title":"Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases","volume":"443","author":"Lin","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2023.105169_bib167","doi-asserted-by":"crossref","DOI":"10.1172\/JCI22217","article-title":"Dysregulation of insulin receptor substrate 2 in \u03b2 cells and brain causes obesity and diabetes","volume":"114","author":"Lin","year":"2004","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.neubiorev.2023.105169_bib168","doi-asserted-by":"crossref","first-page":"811","DOI":"10.2741\/4618","article-title":"Food addiction: a common neurobiological mechanism with drug abuse","volume":"23","author":"Lindgren","year":"2018","journal-title":"Front Biosci. - Landmark"},{"key":"10.1016\/j.neubiorev.2023.105169_bib169","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1523\/JNEUROSCI.4806-11.2012","article-title":"Amygdala central nucleus interacts with dorsolateral striatum to regulate the acquisition of habits","volume":"32","author":"Lingawi","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib170","series-title":"Front. Syst. Neurosci","article-title":"Dorsal striatal circuits for habits, compulsions and addictions","author":"Lipton","year":"2019"},{"key":"10.1016\/j.neubiorev.2023.105169_bib171","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0140-6736(20)30367-6","article-title":"Dementia prevention, intervention, and care: 2020 report of the Lancet Commission","volume":"396","author":"Livingston","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.neubiorev.2023.105169_bib172","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep26527","article-title":"Alteration of functional connectivity in autism spectrum disorder: effect of age and anatomical distance","volume":"6","author":"Long","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neubiorev.2023.105169_bib173","first-page":"2020","article-title":"Metformin ameliorates A \u03b2 pathology by insulin-degrading enzyme in a transgenic mouse model of Alzheimer\u2019s disease","author":"Lu","year":"2020","journal-title":"Oxid. Med Cell Longev."},{"key":"10.1016\/j.neubiorev.2023.105169_bib174","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.psyneuen.2018.04.013","article-title":"Immune system and obsessive-compulsive disorder","volume":"93","author":"Marazziti","year":"2018","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib175","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1080\/13803395.2020.1842333","article-title":"Subjective cognitive rigidity and attention to detail: a cross-cultural validation of the Detail and Flexibility Questionnaire (DFlex) in a French clinical sample","volume":"42","author":"Maria","year":"2020","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib176","doi-asserted-by":"crossref","DOI":"10.2174\/1570159X15666170320104237","article-title":"Glutamate-modulating drugs as a potential therapeutic strategy in obsessive-compulsive disorder","volume":"15","author":"Marinova","year":"2017","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib177","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0091-3057(95)00187-5","article-title":"Mesolimbic dopaminergic system activity as a function of food reward: a microdialysis study","volume":"53","author":"Martel","year":"1996","journal-title":"Pharm. Biochem Behav."},{"key":"10.1016\/j.neubiorev.2023.105169_bib178","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/nature02621","article-title":"Pathways towards and away from Alzheimer\u2019s disease","volume":"430","author":"Mattson","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.neubiorev.2023.105169_bib179","doi-asserted-by":"crossref","first-page":"132","DOI":"10.3171\/2016.1.JNS15601","article-title":"Role of the dorsal anterior cingulate cortex in obsessive-compulsive disorder: converging evidence from cognitive neuroscience and psychiatric neurosurgery","volume":"126","author":"McGovern","year":"2017","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.neubiorev.2023.105169_bib180","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/jnr.490210212","article-title":"Insulin\u2010like growth factor I promotes cell proliferation and oligodendroglial commitment in rat glial progenitor cells developing in vitro","volume":"21","author":"McMorris","year":"1988","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neubiorev.2023.105169_bib181","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1111\/j.1460-9568.2012.08168.x","article-title":"Insulin in the ventral tegmental area reduces hedonic feeding and suppresses dopamine concentration via increased reuptake","volume":"36","author":"Mebel","year":"2012","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib182","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.cmet.2012.10.019","article-title":"Hyperinsulinemia drives diet-induced obesity independently of brain insulin production","volume":"16","author":"Mehran","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.neubiorev.2023.105169_bib183","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.cmet.2012.10.019","article-title":"Hyperinsulinemia drives diet-induced obesity independently of brain insulin production","volume":"16","author":"Mehran","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.neubiorev.2023.105169_bib184","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/0306-4522(94)90520-7","article-title":"Responses of rat mesencephalic dopaminergic neurons to a prolonged period of oxygen deprivation","volume":"63","author":"Mercuri","year":"1994","journal-title":"Neuroscience"},{"key":"10.1016\/j.neubiorev.2023.105169_bib185","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23094641","article-title":"Antidiabetic drugs in the treatment of Alzheimer\u2019s disease","volume":"23","author":"Michailidis","year":"2022","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib186","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1471-4159.2004.02841.x","article-title":"Insulin exerts neuroprotection by counteracting the decrease in cell-surface GABAA receptors following oxygen-glucose deprivation in cultured cortical neurons","volume":"92","author":"Mielke","year":"2005","journal-title":"J. Neurochem"},{"key":"10.1016\/j.neubiorev.2023.105169_bib187","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.tics.2011.11.003","article-title":"Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways","volume":"16","author":"Milad","year":"2012","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib188","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpr.2020.101905","article-title":"Cognitive flexibility in acute anorexia nervosa and after recovery: a systematic review","volume":"81","author":"Miles","year":"2020","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.neubiorev.2023.105169_bib189","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.bbi.2014.04.001","article-title":"Obesity and neuroinflammation: a pathway to cognitive impairment","volume":"42","author":"Miller","year":"2014","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.neubiorev.2023.105169_bib190","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.biopsych.2020.06.022","article-title":"Suppression of corticostriatal circuit activity improves cognitive flexibility and prevents body weight loss in activity-based anorexia in rats","volume":"90","author":"Milton","year":"2021","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib191","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2019.00099","article-title":"A working hypothesis for the role of the cerebellum in impulsivity and compulsivity","volume":"13","author":"Miquel","year":"2019","journal-title":"Front Behav. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib192","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S2213-8587(13)70180-3","article-title":"Endocrine consequences of anorexia nervosa","volume":"2","author":"Misra","year":"2014","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib193","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1002\/jnr.490300214","article-title":"Insulin\u2010like growth factor I stimulates oligodendrocyte development and myelination in rat brain aggregate cultures","volume":"30","author":"Mozell","year":"1991","journal-title":"J. Neurosci. Res"},{"key":"10.1016\/j.neubiorev.2023.105169_bib194","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2019.00308","article-title":"Microglia express insulin-like growth factor-1 in the hippocampus of aged APPswe\/PS1\u0394E9 transgenic mice","volume":"13","author":"Myhre","year":"2019","journal-title":"Front Cell Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib195","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1038\/npp.2016.260","article-title":"Fronto-striatal glutamate in autism spectrum disorder and obsessive compulsive disorder","volume":"42","author":"Naaijen","year":"2017","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib196","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1159\/000070683","article-title":"Factor structure of a modified version of the wisconsin card sorting test: an analysis of executive deficit in Alzheimer\u2019s disease and mild cognitive impairment","volume":"16","author":"Nagahama","year":"2003","journal-title":"Dement Geriatr. Cogn. Disord."},{"key":"10.1016\/j.neubiorev.2023.105169_bib197","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/674164","article-title":"Insulin blocks glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells","volume":"2014","author":"Nampoothiri","year":"2014","journal-title":"Behav. Neurol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib198","article-title":"White matter changes in Alzheimer\u2019s disease: a focus on myelin and oligodendrocytes","volume":"22","author":"Nasrabady","year":"2018","journal-title":"Acta Neuropathol. Commun. 6 Acta Neuropathol. Commun."},{"key":"10.1016\/j.neubiorev.2023.105169_bib199","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1083\/jcb.201105154","article-title":"FoxO limits microtubule stability and is itself negatively regulated by microtubule disruption","volume":"196","author":"Nechipurenko","year":"2012","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib200","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.brat.2006.05.009","article-title":"Impulsivity predicts treatment outcome in obese children","volume":"45","author":"Nederkoorn","year":"2007","journal-title":"Behav. Res Ther."},{"key":"10.1016\/j.neubiorev.2023.105169_bib201","first-page":"905","article-title":"The interactive effect of hunger and impulsivity on food intake and purchase in a virtual supermarket","volume":"33","author":"Nederkoorn","year":"2009","journal-title":"Int J. Obes. 2009 338"},{"key":"10.1016\/j.neubiorev.2023.105169_bib202","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1515\/REVNEURO.2010.21.2.119","article-title":"Cortical GABA, striatal dopamine and midbrain serotonin as the key players in compulsiveand anxiety disorders - results from in vivo imaging studies","volume":"21","author":"Nikolaus","year":"2010","journal-title":"Rev. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib203","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.nicl.2017.07.004","article-title":"Microstructural abnormalities in white and gray matter in obese adolescents with and without type 2 diabetes","volume":"16","author":"Nouwen","year":"2017","journal-title":"NeuroImage Clin."},{"key":"10.1016\/j.neubiorev.2023.105169_bib204","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.ejphar.2005.06.011","article-title":"Insulin induces internalization of the 5-HT2A receptor expressed in HEK293 cells","volume":"518","author":"Ohkura","year":"2005","journal-title":"Eur. J. Pharm."},{"key":"10.1016\/j.neubiorev.2023.105169_bib205","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.bbi.2017.12.009","article-title":"Metformin treatment prevents amyloid plaque deposition and memory impairment in APP\/PS1 mice","volume":"69","author":"Ou","year":"2018","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.neubiorev.2023.105169_bib206","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1111\/j.1471-4159.2005.03289.x","article-title":"Deficits in dopamine clearance and locomotion in hypoinsulinemic rats unmask novel modulation of dopamine transporters by amphetamine","volume":"94","author":"Owens","year":"2005","journal-title":"J. Neurochem"},{"key":"10.1016\/j.neubiorev.2023.105169_bib207","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1111\/j.1471-4159.2005.03289.x","article-title":"Deficits in dopamine clearance and locomotion in hypoinsulinemic rats unmask novel modulation of dopamine transporters by amphetamine","volume":"94","author":"Owens","year":"2005","journal-title":"J. Neurochem"},{"key":"10.1016\/j.neubiorev.2023.105169_bib208","doi-asserted-by":"crossref","first-page":"E1654","DOI":"10.1212\/WNL.0000000000005475","article-title":"Diabetes mellitus and Parkinson disease","volume":"90","author":"Pagano","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib209","series-title":"Indian J. Psychol. Med. 38","first-page":"386","article-title":"Neuroimaging studies in obsessive compulsive disorder: a narrative review","author":"Parmar","year":"2016"},{"key":"10.1016\/j.neubiorev.2023.105169_bib210","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1159\/000054345","article-title":"Food deprivation decreases mRNA and activity of the rat dopamine transporter","volume":"68","author":"Patterson","year":"1998","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib211","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1159\/000054345","article-title":"Food deprivation decreases mRMA and activity of the rat dopamine transporter","volume":"68","author":"Patterson","year":"1998","journal-title":"Neuroendocrinology"},{"issue":"1","key":"10.1016\/j.neubiorev.2023.105169_bib212","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/1097-4679(199501)51:1<48::AID-JCLP2270510109>3.0.CO;2-E","article-title":"Discrimination of cortical from subcortical dementias on the basis of memory and problem-solving tests","volume":"51","author":"Paulsen","year":"1995","journal-title":"J. Clin. Psychol"},{"key":"10.1016\/j.neubiorev.2023.105169_bib213","doi-asserted-by":"crossref","first-page":"11851","DOI":"10.1523\/JNEUROSCI.1700-16.2016","article-title":"Novel roles for the insulin-regulated glucose transporter-4 in hippocampally dependent memory","volume":"36","author":"Pearson-Leary","year":"2016","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib214","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1002\/syn.20831","article-title":"Repeated cocaine exposure decreases Dopamine D2-LIKE RECEPTOR MOdulation of Ca2+ homeostasis in rat nucleus accumbens neurons","volume":"65","author":"Perez","year":"2011","journal-title":"Synapse"},{"key":"10.1016\/j.neubiorev.2023.105169_bib215","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.neuron.2007.01.029","article-title":"LTP Inhibits LTD in the Hippocampus via Regulation of GSK3b","volume":"53","author":"Phane Peineau","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib216","article-title":"Projections from the lateral, basal, and accessory basal nuclei of the amygdala to the hippocampal formation in rat","volume":"403","author":"Pikkarainen","year":"1998","journal-title":"Research in Systems Neuroscience"},{"key":"10.1016\/j.neubiorev.2023.105169_bib217","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.brainres.2004.01.044","article-title":"Biphasic effects of stress upon GLUT8 glucose transporter expression and trafficking in the diabetic rat hippocampus","volume":"1006","author":"Piroli","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.neubiorev.2023.105169_bib218","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/cne.10368","article-title":"Peripheral glucose administration stimulates the translocation of GLUT8 glucose transporter to the endoplasmic reticulum in the rat hippocampus","volume":"452","author":"Piroli","year":"2002","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib219","first-page":"2013","article-title":"Transgenic models of Alzheimer\u2019s disease: better utilization of existing models through viral transgenesis","volume":"1437\u20131448","author":"Platt","year":"1832","journal-title":"Biochim Biophys. Acta"},{"key":"10.1016\/j.neubiorev.2023.105169_bib220","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.neuroscience.2015.12.011","article-title":"Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease","volume":"315","author":"Platt","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.neubiorev.2023.105169_bib221","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/WNR.0000000000001742","article-title":"Disrupted functional connectivity between the nucleus accumbens and posterior cingulate cortex in autism spectrum disorder","volume":"33","author":"Polk","year":"2022","journal-title":"Neuroreport"},{"key":"10.1016\/j.neubiorev.2023.105169_bib222","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1037\/xge0000425","article-title":"Visual-tactile selective attention in autism spectrum condition: an Increased influence of visual distractors","volume":"147","author":"Poole","year":"2018","journal-title":"J. Exp. Psychol. Gen."},{"key":"10.1016\/j.neubiorev.2023.105169_bib223","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1111\/j.0953-816X.2004.03320.x","article-title":"In vivo effects of insulin-like growth factor-I (IGF-I) on prenatal and early postnatal development of the central nervous system","volume":"19","author":"Popken","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib224","series-title":"J. Neuroinflammation","article-title":"Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers - pre-clinical and clinical investigations","author":"Prata","year":"2017"},{"key":"10.1016\/j.neubiorev.2023.105169_bib225","doi-asserted-by":"crossref","first-page":"S62","DOI":"10.1055\/s-0031-1273707","article-title":"Effects of dopamine and glutamate on synaptic plasticity: a computational modeling approach for drug abuse as comorbidity in mood disorders","volume":"44","author":"Qi","year":"2011","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib226","doi-asserted-by":"crossref","first-page":"111","DOI":"10.31887\/DCNS.2009.11.2\/cqiu","article-title":"Epidemiology of Alzheimer\u2019s disease: occurrence, determinants, and strategies toward intervention","volume":"11","author":"Qiu","year":"2009","journal-title":"Dialog-. Clin. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib227","series-title":"Drug Des. Devel. Ther","first-page":"3999","article-title":"Mechanism involved in insulin resistance via accumulation of \u03b2-amyloid and neurofibrillary tangles: link between type 2 diabetes and alzheimer\u2019s disease","author":"Rad","year":"2018"},{"key":"10.1016\/j.neubiorev.2023.105169_bib228","series-title":"Annals of the New York Academy of Sciences","first-page":"355","article-title":"The contribution of the medial prefrontal cortex, orbitofrontal cortex, and dorsomedial striatum to behavioral flexibility","author":"Ragozzino","year":"2007"},{"key":"10.1016\/j.neubiorev.2023.105169_bib229","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/hbm.20870","article-title":"Brain structure and obesity","volume":"31","author":"Raji","year":"2010","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neubiorev.2023.105169_bib230","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1002\/jcb.25376","article-title":"The neuroprotective role of insulin against MPP + -induced Parkinson\u2019s disease in differentiated SH-SY5Y Cells","volume":"117","author":"Ramalingam","year":"2016","journal-title":"J. Cell Biochem"},{"key":"10.1016\/j.neubiorev.2023.105169_bib231","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.eurpsy.2017.08.001","article-title":"Neural correlates of affective and non-affective cognition in obsessive compulsive disorder: a Meta-analysis of functional imaging studies","volume":"46","author":"Rasgon","year":"2017","journal-title":"Eur. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib232","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0006-8993(02)02308-9","article-title":"GLUT8 glucose transporter is localized to excitatory and inhibitory neurons in the rat hippocampus","volume":"932","author":"Reagan","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.neubiorev.2023.105169_bib233","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.exger.2016.07.013","article-title":"Executive functions in patients with Alzheimer\u2019s disease, type 2 diabetes mellitus patients and cognitively healthy older adults","volume":"83","author":"Redondo","year":"2016","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib234","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.nicl.2017.11.006","article-title":"Association between hippocampus volume and symptom profiles in obsessive\u2013compulsive disorder","volume":"17","author":"Reess","year":"2018","journal-title":"NeuroImage Clin."},{"key":"10.1016\/j.neubiorev.2023.105169_bib235","doi-asserted-by":"crossref","first-page":"137","DOI":"10.2337\/dc12-0493","article-title":"Microstructural white matter abnormalities and cognitive functioning in type 2 diabetes: a diffusion tensor imaging study","volume":"36","author":"Reijmer","year":"2013","journal-title":"Diabetes Care"},{"key":"10.1016\/j.neubiorev.2023.105169_bib236","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0896-6273(01)00219-7","article-title":"A developmental switch in neurotransmitter flux enhances synaptic efficacy by affecting AMPA receptor activation","volume":"29","author":"Renger","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib237","doi-asserted-by":"crossref","first-page":"587","DOI":"10.2337\/db16-0917","article-title":"Brain GLUT4 knockout mice have impaired glucose tolerance, decreased insulin sensitivity, and impaired hypoglycemic counterregulation","volume":"66","author":"Reno","year":"2017","journal-title":"Diabetes"},{"key":"10.1016\/j.neubiorev.2023.105169_bib238","doi-asserted-by":"crossref","first-page":"22617","DOI":"10.1073\/pnas.1009152108","article-title":"IL-4\/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity","volume":"107","author":"Ricardo-Gonzalez","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib239","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1212\/WNL.0000000000000269","article-title":"Association of type 2 diabetes with brain atrophy and cognitive impairment","volume":"82","author":"Roberts","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib240","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1186\/s12974-017-1042-z","article-title":"Inflammatory dysregulation of monocytes in pediatric patients with obsessive-compulsive disorder","volume":"14","author":"Rodr\u00edguez","year":"2017","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.neubiorev.2023.105169_bib241","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/S1474-4422(09)70293-5","article-title":"Initial clinical manifestations of Parkinson\u2019s disease: features and pathophysiological mechanisms","volume":"8","author":"Rodriguez-Oroz","year":"2009","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib242","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1007\/s12035-018-1195-5","article-title":"Hyperglycemia-driven neuroinflammation compromises BBB leading to memory loss in both diabetes mellitus (DM) type 1 and type 2 mouse models","volume":"56","author":"Rom","year":"2019","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib243","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.neurobiolaging.2012.08.006","article-title":"A touch screen-automated cognitive test battery reveals impaired attention, memory abnormalities, and increased response inhibition in the TgCRND8 mouse model of Alzheimer\u2019s disease","volume":"34","author":"Romberg","year":"2013","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neubiorev.2023.105169_bib244","doi-asserted-by":"crossref","first-page":"3023","DOI":"10.1093\/brain\/awx232","article-title":"Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer\u2019s disease","volume":"140","author":"Rorabaugh","year":"2017","journal-title":"Brain"},{"key":"10.1016\/j.neubiorev.2023.105169_bib245","series-title":"Mol. Psychiatry","first-page":"290","article-title":"Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis","author":"Rossignol","year":"2012"},{"key":"10.1016\/j.neubiorev.2023.105169_bib246","doi-asserted-by":"crossref","unstructured":"Rotge J.-Y., Guehl D., Dilharreguy B., Cuny E., Tignol J., Bioulac B., Allard M., Burbaud P., Aouizerate B., Rotge J.-Y. Provocation of obsessive-compulsive symptoms: a quantitative voxel-based meta-analysis of functional neuroimaging studies. 2008.","DOI":"10.1139\/jpn.0838"},{"key":"10.1016\/j.neubiorev.2023.105169_bib247","doi-asserted-by":"crossref","first-page":"9925","DOI":"10.1038\/s41598-020-67022-5","article-title":"Regional brain gray matter changes in patients with type 2 diabetes mellitus","volume":"10","author":"Roy","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neubiorev.2023.105169_bib248","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1038\/npp.2011.30","article-title":"Methylphenidate normalizes fronto-striatal underactivation during interference inhibition in medication-nave boys with attention-deficit hyperactivity disorder","volume":"36","author":"Rubia","year":"2011","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib249","series-title":"J. Clin. Invest","first-page":"2764","article-title":"AMPK, insulin resistance, and the metabolic syndrome","author":"Ruderman","year":"2013"},{"key":"10.1016\/j.neubiorev.2023.105169_bib250","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.130681","article-title":"Exercise and metformin counteract altered mitochondrial function in the insulinresistant brain","volume":"4","author":"Ruegsegger","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.neubiorev.2023.105169_bib251","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1177\/0891988713516543","article-title":"Type 2 diabetes and cognitive impairment: contributions from neuroimaging","volume":"27","author":"Ryan","year":"2014","journal-title":"J. Geriatr. Psychiatry Neurol."},{"issue":"4","key":"10.1016\/j.neubiorev.2023.105169_bib252","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1002\/(SICI)1097-4695(19990615)39:4<536::AID-NEU7>3.0.CO;2-J","article-title":"Phosphatidylinositol 3-kinase-mediated regulation of neuronal apoptosis and necrosis by insulin and IGF-I","volume":"39","author":"Ryu","year":"1999","journal-title":"J Neurobiol"},{"key":"10.1016\/j.neubiorev.2023.105169_bib253","doi-asserted-by":"crossref","unstructured":"Salcedo-Tello P., Ortiz-Matamoros A., Arias C. GSK3 function in the brain during development, neuronal plasticity, and neurodegeneration. Int. J. Alzheimers. Dis. 2011 Int J Alzheimers Dis: 2011.","DOI":"10.4061\/2011\/189728"},{"key":"10.1016\/j.neubiorev.2023.105169_bib254","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/nrd2462","article-title":"Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders","author":"Sanacora","year":"2008","journal-title":"Nat. Rev. Drug Disco 7 Nat. Rev. Drug Disco"},{"key":"10.1016\/j.neubiorev.2023.105169_bib255","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0078627","article-title":"Cytochrome c is tyrosine 97 phosphorylated by neuroprotective insulin treatment","volume":"8","author":"Sanderson","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2023.105169_bib256","first-page":"495","article-title":"Phosphoinositide 3-kinases in immunity: lessons from knockout mice","author":"Sasaki","year":"2002","journal-title":"J. Biochem. 131 Jpn. Biochem. Soc."},{"key":"10.1016\/j.neubiorev.2023.105169_bib257","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1038\/s41593-018-0191-4","article-title":"Dopamine neurons create Pavlovian conditioned stimuli with circuit-defined motivational properties","volume":"21","author":"Saunders","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib258","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s10519-008-9208-1","article-title":"Deletion of glucose transporter GLUT8 in mice increases locomotor activity","volume":"38","author":"Schmidt","year":"2008","journal-title":"Behav. Genet"},{"key":"10.1016\/j.neubiorev.2023.105169_bib259","first-page":"1319","article-title":"The effect of intranasal insulin on appetite and mood in women with and without obesity: an experimental medicine study","volume":"46","author":"Schneider","year":"2022","journal-title":"Int J. Obes. 2022 467"},{"key":"10.1016\/j.neubiorev.2023.105169_bib260","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1523\/JNEUROSCI.3779-10.2011","article-title":"Insulin modulates cocaine-sensitive monoamine transporter function and impulsive behavior","volume":"31","author":"Schoffelmeer","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib261","doi-asserted-by":"crossref","first-page":"7084","DOI":"10.1523\/JNEUROSCI.23-18-07084.2003","article-title":"Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation","volume":"23","author":"Schubert","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib262","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.0308724101","article-title":"Role of neuronal insulin resistance in neurodegenerative diseases","volume":"101","author":"Schubert","year":"2004","journal-title":"PNAS"},{"key":"10.1016\/j.neubiorev.2023.105169_bib263","doi-asserted-by":"crossref","unstructured":"Schultz W. Book Review: Reward Signaling by Dopamine Neurons. http:\/\/dx.doi.org\/101177\/107385840100700406 7: 293\u2013302, 2016. doi: 10.1177\/107385840100700406.","DOI":"10.1177\/107385840100700406"},{"key":"10.1016\/j.neubiorev.2023.105169_bib264","doi-asserted-by":"crossref","first-page":"6392","DOI":"10.1523\/JNEUROSCI.1297-04.2004","article-title":"The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages","volume":"24","author":"Schumann","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib265","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0304-3940(03)00547-0","article-title":"The hallucinogen 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI) increases cortical extracellular glutamate levels in rats","volume":"346","author":"Scruggs","year":"2003","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neubiorev.2023.105169_bib266","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1523\/JNEUROSCI.5587-06.2007","article-title":"Dissociable intrinsic connectivity networks for salience processing and executive control","volume":"27","author":"Seeley","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib267","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1111\/j.1476-5381.2011.01230.x","article-title":"Metformin restores endothelial function in aorta of diabetic rats","volume":"163","author":"Sena","year":"2011","journal-title":"Br. J. Pharm."},{"key":"10.1016\/j.neubiorev.2023.105169_bib268","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1124\/jpet.106.115600","article-title":"Insulin replacement restores the behavioral effects of quinpirole and raclopride in streptozotocin-treated rats","volume":"320","author":"Sevak","year":"2007","journal-title":"J. Pharm. Exp. Ther."},{"key":"10.1016\/j.neubiorev.2023.105169_bib269","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2021.766745","article-title":"A preclinical model of computerized cognitive training: touchscreen cognitive testing enhances cognition and hippocampal cellular plasticity in wildtype and alzheimer\u2019s disease mice","volume":"15","author":"Shepherd","year":"2021","journal-title":"Front Behav. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib270","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1097\/00001756-200309150-00011","article-title":"IGF-1 induces neonatal climbing-fibre plasticity in the mature rat cerebellum","volume":"14","author":"Sherrard","year":"2003","journal-title":"Neuroreport"},{"key":"10.1016\/j.neubiorev.2023.105169_bib271","article-title":"Cognitive functioning in obsessive-compulsive disorder: A meta-analysis Article in","author":"Shin","year":"2013","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.neubiorev.2023.105169_bib272","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/nrn1178","article-title":"Prefrontal and medial temporal lobe interactions in long-term memory","volume":"4","author":"Simons","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib273","doi-asserted-by":"crossref","unstructured":"Siniscalco D., Schultz S., Brigida A.L., Antonucci N. Inflammation and neuro-immune dysregulations in autism spectrum disorders. Pharmaceuticals 11 MDPI AG: 2018.","DOI":"10.3390\/ph11020056"},{"key":"10.1016\/j.neubiorev.2023.105169_bib274","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s00702-018-1957-2","article-title":"Dopamine and addiction: what have we learned from 40 years of research","volume":"126","author":"Solinas","year":"2019","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.neubiorev.2023.105169_bib275","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.4161\/auto.21861","article-title":"Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions","volume":"8","author":"Son","year":"2012","journal-title":"Autophagy"},{"key":"10.1016\/j.neubiorev.2023.105169_bib276","doi-asserted-by":"crossref","first-page":"10487","DOI":"10.1158\/0008-5472.CAN-06-1461","article-title":"Activating transcription factor 2 mediates matrix metalloproteinase-2 transcriptional activation induced by p38 in breast epithelial cells","volume":"66","author":"Song","year":"2006","journal-title":"Cancer Res."},{"key":"10.1016\/j.neubiorev.2023.105169_bib277","article-title":"Rare synaptogenesis-impairing mutations in SLITRK5 are associated with obsessive compulsive disorder","volume":"12","author":"Song","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2023.105169_bib278","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s00380-008-1137-7","article-title":"Metformin inhibits nuclear factor \u03baB activation and decreases serum highsensitivity C-reactive protein level in experimental atherogenesis of rabbits","volume":"24","author":"Song-Nan","year":"2009","journal-title":"Heart Vessels"},{"key":"10.1016\/j.neubiorev.2023.105169_bib279","doi-asserted-by":"crossref","first-page":"6379","DOI":"10.1073\/pnas.1817391116","article-title":"Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior","volume":"116","author":"Soto","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib280","doi-asserted-by":"crossref","first-page":"21176","DOI":"10.1074\/jbc.M702039200","article-title":"FOXO1 regulates the expression of 4E-BP1 and inhibits mTOR signaling in mammalian skeletal muscle","volume":"282","author":"Southgate","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neubiorev.2023.105169_bib281","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1212\/WNL.59.2.184","article-title":"Brain structural abnormalities in young children with autism spectrum disorder","volume":"59","author":"Sparks","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib282","doi-asserted-by":"crossref","first-page":"684","DOI":"10.2174\/1567205012666150710104428","article-title":"Insulin modulates In Vitro secretion of cytokines and cytotoxins by human glial cells","volume":"12","author":"Spielman","year":"2015","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.neubiorev.2023.105169_bib283","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3233\/JAD-2005-7107","article-title":"Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer\u2019s disease - is this type 3 diabetes?","volume":"7","author":"Steen","year":"2005","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"10.1016\/j.neubiorev.2023.105169_bib284","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.2337\/db11-1523","article-title":"Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c + cells in adipose tissue and liver","volume":"61","author":"Stefanovic-Racic","year":"2012","journal-title":"Diabetes"},{"key":"10.1016\/j.neubiorev.2023.105169_bib285","series-title":"Nat. Rev. Dis. Prim","article-title":"Obsessive\u2013compulsive disorder","author":"Stein","year":"2019"},{"key":"10.1016\/j.neubiorev.2023.105169_bib286","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.neuron.2020.03.016","article-title":"Amygdala-midbrain connections modulate appetitive and aversive learning","volume":"106","author":"Steinberg","year":"2020","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib287","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1074\/jbc.272.2.971","article-title":"Tumor necrosis factor-\u03b1-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction","volume":"272","author":"Stephens","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neubiorev.2023.105169_bib288","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2011.00054","article-title":"Insulin signaling and autism","volume":"2","author":"Stern","year":"2011","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib289","doi-asserted-by":"crossref","first-page":"3791","DOI":"10.1073\/pnas.1014715108","article-title":"Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage","volume":"108","author":"Stoica","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib290","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms9543","article-title":"Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward","volume":"6","author":"Stouffer","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neubiorev.2023.105169_bib291","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms9543","article-title":"Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward","volume":"6","author":"Stouffer","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neubiorev.2023.105169_bib292","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.euroneuro.2020.02.004","article-title":"Structural and functional MRI of altered brain development in a novel adolescent rat model of quinpirole-induced compulsive checking behavior","volume":"33","author":"Straathof","year":"2020","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib293","series-title":"Cerebellum","first-page":"570","article-title":"The emotional cerebellum","author":"Strata","year":"2015"},{"key":"10.1016\/j.neubiorev.2023.105169_bib294","first-page":"1","article-title":"Decision-making in primary onset middle-age type 2 diabetes mellitus: a BOLD-fMRI study","volume":"7","author":"Sun","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neubiorev.2023.105169_bib295","doi-asserted-by":"crossref","first-page":"3799","DOI":"10.1073\/pnas.1814292116","article-title":"Basolateral amygdala input to the medial prefrontal cortex controls obsessive-compulsive disorder-like checking behavior","volume":"116","author":"Sun","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib296","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S0896-6273(01)00319-1","article-title":"Dopamine production in the caudate putamen restores feeding in dopamine-deficient mice","volume":"30","author":"Szczypka","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib297","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1037\/0735-7044.112.6.1475","article-title":"Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD)","volume":"112","author":"Szechtman","year":"1998","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib298","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1001\/archpsyc.56.10.913","article-title":"Orbital frontal and amygdala volume reductions in obsessive-compulsive disorder","volume":"56","author":"Szeszko","year":"1999","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib299","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1038\/sj.npp.1300399","article-title":"Amygdala volume reductions in pediatric patients with obsessive-compulsive disorder treated with paroxetine: preliminary findings","volume":"29","author":"Szeszko","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neubiorev.2023.105169_bib300","doi-asserted-by":"crossref","first-page":"7036","DOI":"10.1073\/pnas.1000645107","article-title":"Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes","volume":"107","author":"Takeda","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neubiorev.2023.105169_bib301","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3389\/fnmol.2014.00028","article-title":"mTOR signaling and its roles in normal and abnormal brain development","volume":"7","author":"Takei","year":"2014","journal-title":"Front Mol. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib302","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.jpsychires.2004.03.001","article-title":"Set shifting in anorexia nervosa: an examination before and after weight gain, in full recovery and relationship to childhood and adult OCPD traits","volume":"38","author":"Tchanturia","year":"2004","journal-title":"J. Psychiatr. Res"},{"key":"10.1016\/j.neubiorev.2023.105169_bib303","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0028331","article-title":"Poor cognitive flexibility in eating disorders: examining the evidence using the Wisconsin Card Sorting Task","volume":"7","author":"Tchanturia","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2023.105169_bib304","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1159\/000106655","article-title":"Early-stage Alzheimer\u2019s disease and multiple subcortical infarction with mild cognitive impairment: neuropsychological comparison using an easily applicable test battery","volume":"8","author":"Tei","year":"1997","journal-title":"Dement Geriatr. Cogn. Disord."},{"key":"10.1016\/j.neubiorev.2023.105169_bib305","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1093\/brain\/awy264","article-title":"Atrophy subtypes in prodromal Alzheimer\u2019s disease are associated with cognitive decline","volume":"141","author":"Ten Kate","year":"2018","journal-title":"Brain"},{"key":"10.1016\/j.neubiorev.2023.105169_bib306","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1016\/j.neurobiolaging.2013.03.025","article-title":"Impaired glucose tolerance in midlife and longitudinal changes in brain function during aging","volume":"34","author":"Thambisetty","year":"2013","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neubiorev.2023.105169_bib307","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s12311-008-0046-8","article-title":"The cerebellum is involved in reward-based reversal learning","volume":"7","author":"Thoma","year":"2008","journal-title":"Cerebellum"},{"key":"10.1016\/j.neubiorev.2023.105169_bib308","series-title":"J. Med. Assoc. Ga","first-page":"825","article-title":"Psychopharmacologic treatment of obsessive-compulsive disorder","author":"Thorneloe","year":"2019"},{"key":"10.1016\/j.neubiorev.2023.105169_bib309","first-page":"563","article-title":"Emotional processing in obsessive-compulsive disorder: a systematic review and meta-analysis of 25 functional neuroimaging studies","volume":"3","author":"Thorsen","year":"2018","journal-title":"Biol. Psychiatry Cogn. Neurosci. Neuroimaging"},{"key":"10.1016\/j.neubiorev.2023.105169_bib310","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1007\/s00125-008-1041-9","article-title":"Cerebral perfusion in relation to cognitive function and type 2 diabetes","volume":"51","author":"Tiehuis","year":"2008","journal-title":"Diabetologia"},{"key":"10.1016\/j.neubiorev.2023.105169_bib311","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1007\/s10548-019-00744-6","article-title":"Towards a universal taxonomy of macro-scale functional human brain networks","volume":"32","author":"Uddin","year":"2019","journal-title":"Brain Topogr."},{"key":"10.1016\/j.neubiorev.2023.105169_bib312","doi-asserted-by":"crossref","DOI":"10.1152\/ajplung.2000.279.5.L895","article-title":"SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung","volume":"279","author":"Underwood","year":"2000","journal-title":"Am. J. Physiol. - Lung Cell Mol. Physiol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib313","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1097\/NEN.0000000000000108","article-title":"Neuropathology of the anterior midcingulate cortex in young children with autism","volume":"73","author":"Uppal","year":"2014","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib314","series-title":"Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms","first-page":"2512","author":"Vahabzadeh","year":"2014"},{"key":"10.1016\/j.neubiorev.2023.105169_bib315","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.bbadis.2008.09.004","article-title":"Type 2 diabetes mellitus, hypertension, dyslipidemia and obesity: a systematic comparison of their impact on cognition","volume":"1792","author":"Van den Berg","year":"2009","journal-title":"Biochim. Biophys. Acta - Mol. Basis Dis."},{"key":"10.1016\/j.neubiorev.2023.105169_bib316","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s00125-009-1571-9","article-title":"A 4 year follow-up study of cognitive functioning in patients with type 2 diabetes mellitus","volume":"53","author":"Van Den Berg","year":"2010","journal-title":"Diabetologia"},{"key":"10.1016\/j.neubiorev.2023.105169_bib317","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3389\/fnbeh.2019.00092","article-title":"Impaired reversal learning in APPPS1-21 mice in the touchscreen visual discrimination task","volume":"13","author":"Van den Broeck","year":"2019","journal-title":"Front Behav. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib318","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1111\/j.1471-4159.2005.03269.x","article-title":"Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-D-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner","volume":"94","author":"Van Der Heide","year":"2005","journal-title":"J. Neurochem"},{"key":"10.1016\/j.neubiorev.2023.105169_bib319","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1176\/appi.ajp.2017.17010100","article-title":"Cortical and subcortical brain morphometry differences between patients with autism spectrum disorder and healthy individuals across the lifespan: results from the ENIGMA ASD working group","volume":"175","author":"Van Rooij","year":"2018","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib320","doi-asserted-by":"crossref","first-page":"4273","DOI":"10.1096\/fj.14-268482","article-title":"Age-dependent impairment of glucose tolerance in the 3xTg-AD mouse model of Alzheimer\u2019s disease","volume":"29","author":"Vandal","year":"2015","journal-title":"FASEB J."},{"key":"10.1016\/j.neubiorev.2023.105169_bib321","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuroscience.2006.06.027","article-title":"Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat","volume":"142","author":"Vertes","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.neubiorev.2023.105169_bib322","doi-asserted-by":"crossref","first-page":"6686","DOI":"10.1523\/JNEUROSCI.3212-16.2017","article-title":"Unraveling the role of the hippocampus in reversal learning","volume":"37","author":"Vil\u00e0-Ball\u00f3","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib323","doi-asserted-by":"crossref","first-page":"3191","DOI":"10.1098\/rstb.2008.0107","article-title":"Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology","volume":"363","author":"Volkow","year":"2008","journal-title":"Philos. Trans. R. Soc. B Biol. Sci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib324","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1017\/S003329171800212X","article-title":"Dynamic changes in white matter microstructure in anorexia nervosa: findings from a longitudinal study","volume":"49","author":"Von Schwanenflug","year":"2019","journal-title":"Psychol. Med"},{"key":"10.1016\/j.neubiorev.2023.105169_bib325","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.neubiorev.2013.11.001","article-title":"Depression and impulse control disorders in Parkinson\u2019s disease: two sides of the same coin?","volume":"38","author":"Vriend","year":"2014","journal-title":"Neurosci. Biobehav Rev."},{"key":"10.1016\/j.neubiorev.2023.105169_bib326","article-title":"BMI modulates calorie-dependent dopamine changes in accumbens from glucose intake","volume":"9","author":"Wang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.neubiorev.2023.105169_bib327","doi-asserted-by":"crossref","first-page":"773","DOI":"10.3233\/JAD-170786","article-title":"Medical comorbidity in Alzheimer\u2019s disease: a nested case-control study","volume":"63","author":"Wang","year":"2018","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"10.1016\/j.neubiorev.2023.105169_bib328","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S0896-6273(03)00356-8","article-title":"Control of synaptic strength, a novel function of Akt","volume":"38","author":"Wang","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.neubiorev.2023.105169_bib329","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1038\/s41588-019-0439-2","article-title":"Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa","volume":"51","author":"Watson","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neubiorev.2023.105169_bib330","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2014.00088","article-title":"Using mice to model Alzheimer\u2019s dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models","volume":"5","author":"Webster","year":"2014","journal-title":"Front Genet"},{"key":"10.1016\/j.neubiorev.2023.105169_bib331","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1111\/j.1471-4159.1990.tb01219.x","article-title":"Release of immunoreactive insulin from rat brain synaptosomes under depolarizing conditions","volume":"54","author":"Wei","year":"1990","journal-title":"J. Neurochem"},{"key":"10.1016\/j.neubiorev.2023.105169_bib332","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2014.00410","article-title":"Are extremes of consumption in eating disorders related to an altered balance between reward and inhibition","volume":"8","author":"Wierenga","year":"2014","journal-title":"Front Behav. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib333","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1371\/journal.pbio.0050274","article-title":"Hypoinsulinemia regulates amphetamine-induced reverse transport of dopamine","volume":"5","author":"Williams","year":"2007","journal-title":"PLoS Biol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib334","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1038\/nm.2001","article-title":"Normalization of obesity-associated insulin resistance through immunotherapy","volume":"15","author":"Winer","year":"2009","journal-title":"Nat. Med"},{"key":"10.1016\/j.neubiorev.2023.105169_bib335","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1037\/0735-7044.119.5.1389","article-title":"Memory impairment in Obese Zucker rats: An investigation of cognitive function in an animal model of insulin resistance and obesity","volume":"119","author":"Winocur","year":"2005","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib336","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.mito.2010.05.014","article-title":"Mitochondrial dysfunction: A Potential link between neuroinflammation and neurodegeneration?","volume":"10","author":"Witte","year":"2010","journal-title":"Mitochondrion"},{"key":"10.1016\/j.neubiorev.2023.105169_bib337","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/s41380-020-00933-x","article-title":"Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy","volume":"26","author":"Wu","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib338","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.1499","article-title":"Modeling essential connections in obsessive\u2013compulsive disorder patients using functional MRI","volume":"10","author":"Xing","year":"2020","journal-title":"Brain Behav."},{"key":"10.1016\/j.neubiorev.2023.105169_bib339","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.3174\/ajnr.A4740","article-title":"A diffusion tensor imaging study on white matter abnormalities in patients with type 2 diabetes using tract-based spatial statistics","volume":"37","author":"Xiong","year":"2016","journal-title":"Am. J. Neuroradiol."},{"key":"10.1016\/j.neubiorev.2023.105169_bib340","article-title":"The nucleus accumbens: a common target in the comorbidity of depression and addiction","volume":"37","author":"Xu","year":"2020","journal-title":"Front. Neural Circuits 14 Front. Media S. A"},{"key":"10.1016\/j.neubiorev.2023.105169_bib341","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1017\/S0033291718001915","article-title":"Altered resting-state cerebellar-cerebral functional connectivity in obsessive-compulsive disorder","volume":"49","author":"Xu","year":"2019","journal-title":"Psychol. Med"},{"key":"10.1016\/j.neubiorev.2023.105169_bib342","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.bbrc.2011.03.083","article-title":"Voltage-gated K+ channel KCNQ1 regulates insulin secretion in MIN6 \u03b2-cell line","volume":"407","author":"Yamagata","year":"2011","journal-title":"Biochem Biophys. Res Commun."},{"key":"10.1016\/j.neubiorev.2023.105169_bib343","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1038\/sj.bjp.0702905","article-title":"Efficient functional coupling of the human D3 dopamine receptor to G o subtype of G proteins in SH-SY5Y cells","volume":"128","author":"Zaworski","year":"1999","journal-title":"Br. J. Pharm."},{"key":"10.1016\/j.neubiorev.2023.105169_bib344","series-title":"Neurol. Sci","first-page":"9","article-title":"Cerebral insulin, insulin signaling pathway, and brain angiogenesis","author":"Zeng","year":"2016"},{"key":"10.1016\/j.neubiorev.2023.105169_bib345","article-title":"Altered cerebellar-cerebral circuits in patients with type 2 diabetes mellitus","volume":"14","author":"Zhang","year":"2020","journal-title":"Front Neurosci."},{"key":"10.1016\/j.neubiorev.2023.105169_bib346","article-title":"Altered functional connectivity between the cerebellum and the cortico-striato-thalamo-cortical circuit in obsessive-compulsive disorder","volume":"10","author":"Zhang","year":"2019","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib347","doi-asserted-by":"crossref","first-page":"522","DOI":"10.3389\/fpsyt.2019.00522","article-title":"Altered functional connectivity between the cerebellum and the cortico-striato-thalamo-cortical circuit in obsessive-compulsive disorder","volume":"10","author":"Zhang","year":"2019","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.neubiorev.2023.105169_bib348","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.diabres.2016.10.024","article-title":"An updated meta-analysis of cohort studies: diabetes and risk of Alzheimer\u2019s disease","volume":"124","author":"Zhang","year":"2017","journal-title":"Diabetes Res Clin. Pr."},{"key":"10.1016\/j.neubiorev.2023.105169_bib349","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/1753-0407.12826","article-title":"Altered brain structural topological properties in type 2 diabetes mellitus patients without complications","volume":"11","author":"Zhang","year":"2019","journal-title":"J. Diabetes"},{"key":"10.1016\/j.neubiorev.2023.105169_bib350","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1096\/fj.06-7703com","article-title":"Amyloid beta oligomers induce impairment of neuronal insulin receptors","volume":"22","author":"Zhao","year":"2008","journal-title":"FASEB"},{"key":"10.1016\/j.neubiorev.2023.105169_bib351","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.neulet.2009.12.057","article-title":"Impairments in cognition and resting-state connectivity of the hippocampus in elderly subjects with type 2 diabetes","volume":"473","author":"Zhou","year":"2010","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neubiorev.2023.105169_bib352","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.ajem.2017.07.070","article-title":"Anti-inflammatory and organ protective effect of insulin in scalded MODS rats without controlling hyperglycemia","volume":"36","author":"Zhu","year":"2018","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.neubiorev.2023.105169_bib353","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1038\/s41593-019-0394-3","article-title":"Compulsivity and impulsivity traits linked to attenuated developmental frontostriatal myelination trajectories","volume":"22","author":"Ziegler","year":"2019","journal-title":"Nat. Neurosci."}],"container-title":["Neuroscience &amp; Biobehavioral Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763423001380?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763423001380?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T10:27:36Z","timestamp":1758968856000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0149763423001380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":353,"alternative-id":["S0149763423001380"],"URL":"https:\/\/doi.org\/10.1016\/j.neubiorev.2023.105169","relation":{},"ISSN":["0149-7634"],"issn-type":[{"value":"0149-7634","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Insulin and disorders of behavioural flexibility","name":"articletitle","label":"Article Title"},{"value":"Neuroscience & Biobehavioral Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neubiorev.2023.105169","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"105169"}}