{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T19:52:43Z","timestamp":1793649163836,"version":"4.5.1"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T00:00:00Z","timestamp":1766188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience & Biobehavioral Reviews"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.neubiorev.2025.106531","type":"journal-article","created":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T23:16:39Z","timestamp":1766272599000},"page":"106531","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Malondialdehyde in cognitive impairment: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"181","author":[{"given":"Stefano","family":"Zoroddu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Sedda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arduino A.","family":"Mangoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciriaco","family":"Carru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Zinellu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neubiorev.2025.106531_bib1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.33879\/AMH.151.2022.08067","article-title":"The correlation between oxidative stress and cognitive decline in Egyptian elderly with mild cognitive impairment","volume":"15","author":"Aly","year":"2024","journal-title":"Aging Med. Healthc."},{"key":"10.1016\/j.neubiorev.2025.106531_bib2","doi-asserted-by":"crossref","first-page":"1237469","DOI":"10.3389\/fnagi.2023.1237469","article-title":"Several dementia subtypes and mild cognitive impairment share brain reduction of neurotransmitter precursor amino acids, impaired energy metabolism, and lipid hyperoxidation","volume":"15","author":"Aquilani","year":"2023","journal-title":"Front Aging Neurosci."},{"key":"10.1016\/j.neubiorev.2025.106531_bib3","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.clinbiochem.2006.09.005","article-title":"Determination of malondialdehyde, reduced glutathione levels and APOE4 allele frequency in late-onset Alzheimer\u2019s disease in Denizli, Turkey","volume":"40","author":"Aybek","year":"2007","journal-title":"Clin. Biochem"},{"key":"10.1016\/j.neubiorev.2025.106531_bib4","article-title":"Preliminary data on the interaction between some biometals and oxidative stress status in mild cognitive impairment and alzheimer\u2019s disease patients","volume":"2017","author":"Balmu","year":"2017","journal-title":"Oxid. Med Cell Longev."},{"key":"10.1016\/j.neubiorev.2025.106531_bib5","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jclinepi.2010.07.015","article-title":"GRADE guidelines: 3. Rating the quality of evidence","volume":"64","author":"Balshem","year":"2011","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib6","doi-asserted-by":"crossref","first-page":"71","DOI":"10.17219\/acem\/111377","article-title":"Paraoxonase 1 decline and lipid peroxidation rise reflect a degree of brain atrophy and vascular impairment in dementia","volume":"29","author":"Bednarz-Misa","year":"2020","journal-title":"Adv. Clin. Exp. Med."},{"key":"10.1016\/j.neubiorev.2025.106531_bib7","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2307\/2533446","article-title":"Operating characteristics of a rank correlation test for publication bias","volume":"50","author":"Begg","year":"1994","journal-title":"Biometrics"},{"key":"10.1016\/j.neubiorev.2025.106531_bib8","doi-asserted-by":"crossref","first-page":"1478373","DOI":"10.3389\/fonc.2024.1478373","article-title":"Aldehyde-induced DNA-protein crosslinks- DNA damage, repair and mutagenesis","volume":"14","author":"Blouin","year":"2024","journal-title":"Front Oncol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib9","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/ageing\/30.3.235","article-title":"Antioxidant defences and oxidative stress markers in erythrocytes and plasma from normally nourished elderly Alzheimer patients","volume":"30","author":"Bourdel-Marchasson","year":"2001","journal-title":"Age Ageing"},{"key":"10.1016\/j.neubiorev.2025.106531_bib10","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2288-11-41","article-title":"Quantifying, displaying and accounting for heterogeneity in the meta-analysis of RCTs using standard and generalised Q statistics","volume":"11","author":"Bowden","year":"2011","journal-title":"BMC Med Res Method."},{"key":"10.1016\/j.neubiorev.2025.106531_bib11","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1007\/s10072-020-04704-y","article-title":"Positive association of a Sirt1 variant and parameters of oxidative stress on Alzheimer\u2019s disease","volume":"42","author":"Camporez","year":"2021","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.neubiorev.2025.106531_bib12","doi-asserted-by":"crossref","first-page":"5782","DOI":"10.3390\/ijms26125782","article-title":"Oxidative stress in neurodegenerative disorders: a key driver in impairing skeletal muscle health","volume":"26","author":"Castelli","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neubiorev.2025.106531_bib13","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.redox.2018.01.008","article-title":"13 reasons why the brain is susceptible to oxidative stress","volume":"15","author":"Cobley","year":"2018","journal-title":"Redox Biol."},{"issue":"1","key":"10.1016\/j.neubiorev.2025.106531_bib14","doi-asserted-by":"crossref","DOI":"10.1186\/s13024-019-0333-5","article-title":"The neuropathological diagnosis of Alzheimer\u2019s disease","volume":"14","author":"Deture","year":"2019","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.neubiorev.2025.106531_bib15","doi-asserted-by":"crossref","first-page":"270","DOI":"10.3390\/biomedicines12020270","article-title":"A Systematic review and meta-analysis of mean platelet volume and platelet distribution width in patients with obstructive sleep apnoea syndrome","volume":"12","author":"Di Lorenzo","year":"2024","journal-title":"Biomedicines"},{"key":"10.1016\/j.neubiorev.2025.106531_bib16","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.0006-341X.2000.00455.x","article-title":"Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"Duval","year":"2000","journal-title":"Biometrics"},{"key":"10.1016\/j.neubiorev.2025.106531_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.729757","article-title":"Oxidative stress and cognitive decline: the neuroprotective role of natural antioxidants","volume":"15","author":"Franzoni","year":"2021","journal-title":"Front Neurosci."},{"key":"10.1016\/j.neubiorev.2025.106531_bib18","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1159\/000319452","article-title":"Oxidative imbalance in different neurodegenerative diseases with memory impairment","volume":"8","author":"Gironi","year":"2011","journal-title":"Neurodegener. Dis."},{"key":"10.1016\/j.neubiorev.2025.106531_bib19","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.eurger.2016.05.001","article-title":"Elevated platelet microparticles levels are associated with lipidic oxidation and inflammatory profiles in Alzheimer\u2019s disease","volume":"7","author":"Gon\u00e7alves","year":"2016","journal-title":"Eur. Geriatr. Med"},{"key":"10.1016\/j.neubiorev.2025.106531_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2020.110951","article-title":"DNA methylation of the RE-1 silencing transcription factor in peripheral blood mononuclear cells and gene expression of antioxidant enzyme in patients with late-onset Alzheimer disease","volume":"136","author":"Gonz\u00e1lez-Mundo","year":"2020","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib21","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.fct.2013.07.013","article-title":"Alzheimer\u2019s disease treated patients showed different patterns for oxidative stress and inflammation markers","volume":"61","author":"Gubandru","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib22","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1447-0594.2009.00571.x","article-title":"Lipids\u2019 peroxidation markers in Alzheimer\u2019s disease and vascular dementia","volume":"10","author":"Gustaw-Rothenberg","year":"2010","journal-title":"Geriatr. Gerontol. Int"},{"key":"10.1016\/j.neubiorev.2025.106531_bib23","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat. Med"},{"key":"10.1016\/j.neubiorev.2025.106531_bib24","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3390\/jox15020050","article-title":"Serum and Cerebrospinal Fluid Malondialdehyde Levels in Patients with Mild Cognitive Impairment","volume":"15","author":"Ioannidou","year":"2025","journal-title":"J. Xenobiotics"},{"key":"10.1016\/j.neubiorev.2025.106531_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2024.102481","article-title":"Pathogenesis, diagnostics, and therapeutics for Alzheimer\u2019s disease: Breaking the memory barrier","volume":"101","author":"Kamatham","year":"2024","journal-title":"Ageing Res Rev."},{"key":"10.1016\/j.neubiorev.2025.106531_bib26","doi-asserted-by":"crossref","first-page":"892","DOI":"10.2174\/1567205020666230206142738","article-title":"Pesticide Exposure and Alzheimer\u2019s Disease: A Case-control Study","volume":"19","author":"Kiani","year":"2023","journal-title":"Curr. Alzheimer Res"},{"key":"10.1016\/j.neubiorev.2025.106531_bib27","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/s12011-014-9930-x","article-title":"Evaluation of selenium, redox status and their association with plasma amyloid\/tau in Alzheimer\u2019s disease","volume":"158","author":"Krishnan","year":"2014","journal-title":"Biol. Trace Elem. Res"},{"key":"10.1016\/j.neubiorev.2025.106531_bib28","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1080\/00207454.2018.1521401","article-title":"Diffusion tensor imaging based white matter changes and antioxidant enzymes status for early identification of mild cognitive impairment","volume":"129","author":"Kumar","year":"2019","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/j.neubiorev.2025.106531_bib29","doi-asserted-by":"crossref","first-page":"7152","DOI":"10.3390\/ijms21197152","article-title":"Neuroprotective Effect of Antioxidants in the Brain","volume":"21","author":"Lee","year":"2020","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.neubiorev.2025.106531_bib30","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jclinepi.2009.06.006","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"62","author":"Liberati","year":"2009","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib31","first-page":"1","article-title":"High Serum Levels of Malondialdehyde and 8-OHdG are both Associated with Early Cognitive Impairment in Patients with Acute Ischaemic Stroke","volume":"7","author":"Liu","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neubiorev.2025.106531_bib32","doi-asserted-by":"crossref","first-page":"823","DOI":"10.3233\/JAD-2012-121528","article-title":"Oxidative stress in Alzheimer\u2019s disease and mild cognitive impairment with high sensitivity and specificity","volume":"33","author":"L\u00f3pez","year":"2013","journal-title":"J. Alzheimer\u2019S. Dis."},{"key":"10.1016\/j.neubiorev.2025.106531_bib33","doi-asserted-by":"crossref","DOI":"10.1177\/2050312115626731","article-title":"Apolipoprotein E \u03b54 allele and malondialdehyde level are independent risk factors for Alzheimer\u2019s disease","volume":"4","author":"L\u00f3pez-Riquelme","year":"2016","journal-title":"SAGE Open Med"},{"key":"10.1016\/j.neubiorev.2025.106531_bib34","doi-asserted-by":"crossref","first-page":"178","DOI":"10.4103\/1673-5374.264473","article-title":"20S proteasome and glyoxalase 1 activities decrease in erythrocytes derived from Alzheimer\u2019s disease patients","volume":"15","author":"Lv","year":"2020","journal-title":"Neural Regen. Res"},{"key":"10.1016\/j.neubiorev.2025.106531_bib35","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s11064-008-9789-3","article-title":"Metalloproteinase\u2019s activity and oxidative stress in mild cognitive impairment and alzheimer\u2019s disease","volume":"34","author":"Mart\u00edn-Arag\u00f3n","year":"2009","journal-title":"Neurochem. Res"},{"key":"10.1016\/j.neubiorev.2025.106531_bib36","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3233\/JAD-190198","article-title":"Altered Redox State in Whole Blood Cells from Patients with Mild Cognitive Impairment and Alzheimer\u2019s Disease","volume":"71","author":"Mart\u00ednez De Toda","year":"2019","journal-title":"J. Alzheimer\u2019S. Dis."},{"key":"10.1016\/j.neubiorev.2025.106531_bib37","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1093\/qjmed\/94.9.485","article-title":"Increased oxidative stress in Alzheimer\u2019s disease as assessed with 4-hydroxynonenal but not malondialdehyde","volume":"94","author":"McGrath","year":"2001","journal-title":"QJM Int. J. Med."},{"key":"10.1016\/j.neubiorev.2025.106531_bib38","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3233\/JAD-142511","article-title":"Amnestic mild cognitive impairment and conversion to alzheimer\u2019s disease: Insulin resistance and glycoxidation as early biomarker clusters","volume":"45","author":"Monacelli","year":"2015","journal-title":"J. Alzheimer\u2019S. Dis."},{"key":"10.1016\/j.neubiorev.2025.106531_bib39","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1001\/archneur.58.3.397","article-title":"Mild Cognitive Impairment Represents Early-Stage Alzheimer Disease","volume":"58","author":"Morris","year":"2001","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib40","doi-asserted-by":"crossref","DOI":"10.1111\/bpa.13202","article-title":"Lipid metabolism and oxidative stress in patients with Alzheimer\u2019s disease and amnestic mild cognitive impairment","volume":"34","author":"Nie","year":"2024","journal-title":"Brain Pathol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib41","doi-asserted-by":"crossref","first-page":"517","DOI":"10.3390\/antiox12020517","article-title":"Oxidative Stress and Antioxidants in Neurodegenerative Disorders","volume":"12","author":"Olufunmilayo","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.neubiorev.2025.106531_bib42","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.neulet.2009.11.033","article-title":"Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer\u2019s disease","volume":"469","author":"Padurariu","year":"2010","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neubiorev.2025.106531_bib43","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3390\/geriatrics5040084","article-title":"Global Cognitive Impairment Prevalence and Incidence in Community Dwelling Older Adults\u2014A Systematic Review","volume":"5","author":"Pais","year":"2020","journal-title":"Geriatrics"},{"key":"10.1016\/j.neubiorev.2025.106531_bib44","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.3390\/antiox10071053","article-title":"Circulating malondialdehyde concentrations in obstructive sleep apnea (Osa): A systematic review and meta-analysis with meta-regression","volume":"10","author":"Pau","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.neubiorev.2025.106531_bib45","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1159\/000080027","article-title":"Plasma antioxidant status, immunoglobulin G oxidation and lipid peroxidation in demented patients: Relevance to Alzheimer disease and vascular dementia","volume":"18","author":"Polidori","year":"2004","journal-title":"Dement Geriatr. Cogn. Disord."},{"key":"10.1016\/j.neubiorev.2025.106531_bib46","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2017.00328","article-title":"Study on analysis of peripheral biomarkers for Alzheimer\u2019s disease diagnosis","volume":"8","author":"Rani","year":"2017","journal-title":"Front Neurol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib47","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.nbd.2013.07.005","article-title":"Oxidative stress in blood in Alzheimer\u2019s disease and mild cognitive impairment: A meta-analysis","volume":"59","author":"Schrag","year":"2013","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neubiorev.2025.106531_bib48","doi-asserted-by":"crossref","first-page":"715","DOI":"10.2147\/NDT.S3268","article-title":"Cognitive impairment and Alzheimer\u2019s disease: Links with oxidative stress and cholesterol metabolism","volume":"4","author":"Sekler","year":"2008","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"10.1016\/j.neubiorev.2025.106531_bib49","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1080\/09273948.2020.1740281","article-title":"The Relationship between Ocular Vascular Changes and the Levels of Malondialdehyde and Vascular Endothelial Growth Factor in Patients with Inflammatory Bowel Disease","volume":"29","author":"Sengul Samanci","year":"2021","journal-title":"Ocul. Immunol. Inflamm."},{"key":"10.1016\/j.neubiorev.2025.106531_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101546","article-title":"Advanced glycation end products and protein carbonyl levels in plasma reveal sex-specific differences in Parkinson\u2019s and Alzheimer\u2019s disease","volume":"34","author":"Sharma","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib51","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3390\/mps3040066","article-title":"Detecting Oxidative Stress Biomarkers in Neurodegenerative Disease Models and Patients","volume":"3","author":"Sidorova","year":"2020","journal-title":"Methods Protoc."},{"key":"10.1016\/j.neubiorev.2025.106531_bib52","doi-asserted-by":"crossref","first-page":"463","DOI":"10.2174\/156720510791383822","article-title":"The Serum Protein and Lipid Oxidation Marker Levels in Alzheimers Disease and Effects of Cholinesterase Inhibitors and Antipsychotic Drugs Therapy","volume":"7","author":"Sinem","year":"2010","journal-title":"Curr. Alzheimer Res"},{"key":"10.1016\/j.neubiorev.2025.106531_bib53","doi-asserted-by":"crossref","first-page":"1227112","DOI":"10.3389\/fnagi.2023.1227112","article-title":"Evidence from a meta-analysis and systematic review reveals the global prevalence of mild cognitive impairment","volume":"15","author":"Song","year":"2023","journal-title":"Front Aging Neurosci."},{"key":"10.1016\/j.neubiorev.2025.106531_bib54","unstructured":"Statistical Power Analysis for the Behavioral Sciences - Jacob Cohen - Google Libri n.d. \u3008https:\/\/books.google.it\/books?hl=it&lr=&id=rEe0BQAAQBAJ&oi=fnd&pg=PP1&ots=sxTZQwRWt6&sig=Kt4dZ1N36LK-_BUatMXVLy4VpiI&redir_esc=y#v=onepage&q&f=false\u3009 (accessed March 8, 2024)."},{"key":"10.1016\/j.neubiorev.2025.106531_bib55","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/S0895-4356(01)00377-8","article-title":"Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis","volume":"54","author":"Sterne","year":"2001","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib56","doi-asserted-by":"crossref","first-page":"S384","DOI":"10.4103\/jpbs.jpbs_1786_24","article-title":"Role of oxidative stress markers F2-isoprostanes and presenilin-1 in clinical diagnosed alzheimer\u2019s diseases","volume":"17","author":"Timalsina","year":"2025","journal-title":"J. Pharm. Bioallied Sci."},{"key":"10.1016\/j.neubiorev.2025.106531_bib57","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3390\/antiox14030297","article-title":"Oxidative stress in brain function","volume":"14","author":"Trofin","year":"2025","journal-title":"Antioxidants"},{"key":"10.1016\/j.neubiorev.2025.106531_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2021.111344","article-title":"The pleiotropic beneficial intervention of olive oil intake on the Alzheimer\u2019s disease onset via fibrinolytic system","volume":"150","author":"Tzekaki","year":"2021","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.neubiorev.2025.106531_bib59","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2288-14-135","article-title":"Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range","volume":"14","author":"Wan","year":"2014","journal-title":"BMC Med Res Method."},{"key":"10.1016\/j.neubiorev.2025.106531_bib60","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.neuroscience.2024.12.057","article-title":"The investigation of peripheral inflammatory and oxidative stress biomarkers in dementia with Lewy Bodies, compared with Alzheimer\u2019s Disease, and mild cognitive impairment","volume":"568","author":"Yu","year":"2025","journal-title":"Neuroscience"},{"key":"10.1016\/j.neubiorev.2025.106531_bib61","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.nut.2015.08.004","article-title":"Dietary pattern and antioxidants in plasma and erythrocyte in patients with mild cognitive impairment from China","volume":"32","author":"Yuan","year":"2016","journal-title":"Nutrition"},{"key":"10.1016\/j.neubiorev.2025.106531_bib62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-021-03456-9","article-title":"Salivary gland dysfunction and salivary redox imbalance in patients with Alzheimer\u2019s disease","volume":"11","author":"Zalewska","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neubiorev.2025.106531_bib63","doi-asserted-by":"crossref","first-page":"823","DOI":"10.2174\/1567205017666201203123046","article-title":"Association between oxidative stress and altered cholesterol metabolism in alzheimer\u2019s disease patients","volume":"17","author":"Zarrouk","year":"2020","journal-title":"Curr. Alzheimer Res"},{"key":"10.1016\/j.neubiorev.2025.106531_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.cca.2024.119838","article-title":"Resistin and omentin in breast cancer: A systematic review and meta-analysis","volume":"562","author":"Zoroddu","year":"2024","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.neubiorev.2025.106531_bib65","doi-asserted-by":"crossref","DOI":"10.1111\/eci.14281","article-title":"The association between bilirubin concentrations and inflammatory bowel disease: Insights from a systematic review and meta-analysis","volume":"54","author":"Zoroddu","year":"2024","journal-title":"Eur. J. Clin. Invest"},{"key":"10.1016\/j.neubiorev.2025.106531_bib66","doi-asserted-by":"crossref","DOI":"10.1111\/eci.14361","article-title":"Vascular endothelial growth factor in inflammatory bowel disease: A systematic review and meta-analysis","volume":"55","author":"Zoroddu","year":"2025","journal-title":"Eur. J. Clin. Invest"}],"container-title":["Neuroscience & Biobehavioral Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763425005329?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0149763425005329?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T16:53:50Z","timestamp":1781456030000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0149763425005329"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":66,"alternative-id":["S0149763425005329"],"URL":"https:\/\/doi.org\/10.1016\/j.neubiorev.2025.106531","relation":{},"ISSN":["0149-7634"],"issn-type":[{"value":"0149-7634","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Malondialdehyde in cognitive impairment: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Neuroscience & Biobehavioral Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neubiorev.2025.106531","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106531"}}