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Psychol."},{"key":"10.1016\/j.neubiorev.2026.106916_b71","series-title":"Principles of behavior: an introduction to behavior theory.","author":"Hull","year":"1943"},{"key":"10.1016\/j.neubiorev.2026.106916_b72","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.brat.2017.04.013","article-title":"Distraction\/suppression and distress endurance diminish the extent to which generalized conditioned fear is associated with maladaptive behavioral avoidance","volume":"96","author":"Hunt","year":"2017","journal-title":"Behav. Res. Ther."},{"issue":"4","key":"10.1016\/j.neubiorev.2026.106916_b73","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1037\/abn0000422","article-title":"Anxiety sensitivity and intolerance of uncertainty facilitate associations between generalized pavlovian fear and maladaptive avoidance decisions.","volume":"128","author":"Hunt","year":"2019","journal-title":"J. Abnorm. Psychol."},{"issue":"3","key":"10.1016\/j.neubiorev.2026.106916_b74","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.cognition.2009.01.008","article-title":"A Bayesian formulation of behavioral control","volume":"113","author":"Huys","year":"2009","journal-title":"Cognition"},{"key":"10.1016\/j.neubiorev.2026.106916_b75","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.74149","article-title":"Different brain systems support learning from received and avoided pain during human pain-avoidance learning","volume":"11","author":"Jepma","year":"2022","journal-title":"Elife"},{"issue":"45","key":"10.1016\/j.neubiorev.2026.106916_b76","doi-asserted-by":"crossref","first-page":"12868","DOI":"10.1073\/pnas.1609094113","article-title":"Adaptive integration of habits into depth-limited planning defines a habitual-goal\u2013directed spectrum","volume":"113","author":"Keramati","year":"2016","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.neubiorev.2026.106916_b77","doi-asserted-by":"crossref","DOI":"10.1016\/j.brat.2021.103993","article-title":"Fear learning, avoidance, and generalization are more context-dependent for adults than adolescents","volume":"147","author":"Klein","year":"2021","journal-title":"Behav. Res. Ther."},{"key":"10.1016\/j.neubiorev.2026.106916_b78","doi-asserted-by":"crossref","DOI":"10.1016\/j.brat.2020.103712","article-title":"Decomposing conditioned avoidance performance with computational models","volume":"133","author":"Krypotos","year":"2020","journal-title":"Behav. Res. Ther."},{"issue":"3","key":"10.1016\/j.neubiorev.2026.106916_b79","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1177\/2167702613503139","article-title":"Avoided by association: Acquisition, extinction, and renewal of avoidance tendencies toward conditioned fear stimuli","volume":"2","author":"Krypotos","year":"2014","journal-title":"Clin. Psychol. Sci."},{"key":"10.1016\/j.neubiorev.2026.106916_b80","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3389\/fnbeh.2015.00189","article-title":"Avoidance learning: a review of theoretical models and recent developments","volume":"9","author":"Krypotos","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.neubiorev.2026.106916_b81","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jbtep.2018.02.006","article-title":"Testing a novelty-based extinction procedure for the reduction of conditioned avoidance","volume":"60","author":"Krypotos","year":"2018","journal-title":"J. Behav. Ther. Exp. Psychiatry"},{"key":"10.1016\/j.neubiorev.2026.106916_b82","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.brat.2018.10.011","article-title":"The validity of human avoidance paradigms","volume":"111","author":"Krypotos","year":"2018","journal-title":"Behav. Res. Ther."},{"key":"10.1016\/j.neubiorev.2026.106916_b83","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbtep.2022.101812","article-title":"Experimental psychopathology can benefit from registered reports","volume":"79","author":"Krypotos","year":"2023","journal-title":"J. Behav. Ther. Exp. Psychiatry"},{"issue":"8","key":"10.1016\/j.neubiorev.2026.106916_b84","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1073\/pnas.1400335111","article-title":"Coming to terms with fear","volume":"111","author":"LeDoux","year":"2014","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.neubiorev.2026.106916_b85","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/mp.2016.166","article-title":"The birth, death and resurrection of avoidance: a reconceptualization of a troubled paradigm","volume":"22","author":"LeDoux","year":"2017","journal-title":"Mol. 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Behav."},{"issue":"4","key":"10.1016\/j.neubiorev.2026.106916_b102","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1037\/rev0000033","article-title":"Learned helplessness at fifty: Insights from neuroscience.","volume":"123","author":"Maier","year":"2016","journal-title":"Psychol Rev"},{"issue":"2","key":"10.1016\/j.neubiorev.2026.106916_b103","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0005-7894(88)80045-5","article-title":"A laboratory demonstration of persistent human avoidance","volume":"19","author":"Malloy","year":"1988","journal-title":"Behav. Ther."},{"issue":"7","key":"10.1016\/j.neubiorev.2026.106916_b104","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1009134","article-title":"Internality and the internalisation of failure: Evidence from a novel task","volume":"17","author":"Mancinelli","year":"2021","journal-title":"PLoS Comput. Biol."},{"issue":"6","key":"10.1016\/j.neubiorev.2026.106916_b105","doi-asserted-by":"crossref","first-page":"435","DOI":"10.3758\/BF03332655","article-title":"The relationship between punishment and unavoidability in eliminating avoidance behavior in humans","volume":"23","author":"Maxwell","year":"1971","journal-title":"Psychon. Sci."},{"issue":"5","key":"10.1016\/j.neubiorev.2026.106916_b106","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1097\/j.pain.0000000000000483","article-title":"Acquisition and extinction of operant pain-related avoidance behavior using a 3 degrees-of-freedom robotic arm","volume":"157","author":"Meulders","year":"2016","journal-title":"Pain"},{"key":"10.1016\/j.neubiorev.2026.106916_b107","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.brat.2014.03.009","article-title":"Maladaptive behavioral consequences of conditioned fear-generalization: a pronounced, yet sparsely studied, feature of anxiety pathology","volume":"57","author":"van Meurs","year":"2014","journal-title":"Behav. Res. 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