{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T04:28:28Z","timestamp":1764131308280},"reference-count":31,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurochemistry International"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1016\/j.neuint.2009.06.002","type":"journal-article","created":{"date-parts":[[2009,6,12]],"date-time":"2009-06-12T12:30:30Z","timestamp":1244809830000},"page":"606-609","source":"Crossref","is-referenced-by-count":24,"title":["Neuregulin 1-stimulated phosphorylation of AKT in psychotic disorders and its relationship with neurocognitive functions"],"prefix":"10.1016","volume":"55","author":[{"given":"Szabolcs","family":"K\u00e9ri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imola","family":"Seres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oguz","family":"Kelemen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Benedek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuint.2009.06.002_bib1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.neuint.2008.06.011","article-title":"Relative role of upstream regulators of Akt, ERK and CREB in NCAM- and FGF2-mediated signalling","volume":"53","author":"Ditlevsen","year":"2008","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neuint.2009.06.002_bib2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/ng1296","article-title":"Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia","volume":"36","author":"Emamian","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neuint.2009.06.002_bib3","series-title":"Structured Clinical Interview for DSM-IV Axis I Disorders, Clinician Version (SCID-CV)","author":"First","year":"1996"},{"key":"10.1016\/j.neuint.2009.06.002_bib4","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1176\/ajp.156.12.1944","article-title":"Repeatable battery for the assessment of neuropsychological status as a screening test in schizophrenia. I. Sensitivity, reliability, and validity","volume":"156","author":"Gold","year":"1999","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neuint.2009.06.002_bib5","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/oxfordjournals.schbul.a033430","article-title":"Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the \u201cright stuff\u201d?","volume":"26","author":"Green","year":"2000","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.neuint.2009.06.002_bib6","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1038\/nn1795","article-title":"A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms","volume":"9","author":"Hall","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuint.2009.06.002_bib7","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.biopsych.2005.11.002","article-title":"Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology","volume":"60","author":"Harrison","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuint.2009.06.002_bib8","doi-asserted-by":"crossref","first-page":"e1000277","DOI":"10.1371\/journal.pgen.1000277","article-title":"A PI3-kinase-mediated negative feedback regulates neuronal excitability","volume":"4","author":"Howlett","year":"2008","journal-title":"PLoS Genet."},{"key":"10.1016\/j.neuint.2009.06.002_bib9","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1471-4159.2006.04033.x","article-title":"Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia","volume":"99","author":"Ide","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neuint.2009.06.002_bib10","doi-asserted-by":"crossref","first-page":"e1369","DOI":"10.1371\/journal.pone.0001369","article-title":"Neuregulin-1 regulates cell adhesion via an ErbB2\/phosphoinositide-3 kinase\/Akt-dependent pathway: potential implications for schizophrenia and cancer","volume":"26","author":"Kanakry","year":"2007","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuint.2009.06.002_bib11","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/mp.2008.1","article-title":"Effects of a neuregulin 1 variant on conversion to schizophrenia and schizophreniform disorder in people at high-risk for psychosis","volume":"14","author":"K\u00e9ri","year":"2009","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neuint.2009.06.002_bib12","unstructured":"K\u00e9ri, S., Seres, I., Kelemen, O., Benedek, G., in press. The relationship among neuregulin 1-stimulated phosphorylation of AKT, psychosis proneness, and habituation of arousal in non-clinical individuals. Schizophr. Bull."},{"key":"10.1016\/j.neuint.2009.06.002_bib13","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.neuint.2006.09.006","article-title":"How do glial-neuronal interactions fit into current neurotransmitter hypotheses of schizophrenia?","volume":"50","author":"Kondziella","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neuint.2009.06.002_bib14","doi-asserted-by":"crossref","first-page":"16906","DOI":"10.1073\/pnas.0604994103","article-title":"Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning","volume":"103","author":"Lai","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neuint.2009.06.002_bib15","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.ijrobp.2003.06.002","article-title":"Signal transduction and oncogenesis by ErbB\/HER receptors","volume":"58","author":"Marmor","year":"2004","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.neuint.2009.06.002_bib16","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.neuint.2007.06.018","article-title":"Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1)","volume":"52","author":"Matsuzaki","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neuint.2009.06.002_bib17","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/nrn2392","article-title":"Neuregulin 1 in neural development, synaptic plasticity and schizophrenia","volume":"9","author":"Mei","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuint.2009.06.002_bib18","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.neuint.2007.06.019","article-title":"Phencyclidine animal models of schizophrenia: approaches from abnormality of glutamatergic neurotransmission and neurodevelopment","volume":"51","author":"Mouri","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neuint.2009.06.002_bib19","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/sj.mp.4001817","article-title":"Association of the NRG1 gene and schizophrenia: a meta-analysis","volume":"11","author":"Munaf\u00f2","year":"2006","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neuint.2009.06.002_bib20","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.neuint.2007.03.013","article-title":"Oxygen restriction of neonate rats elevates neuregulin-1alpha isoform levels: possible relationship to schizophrenia","volume":"51","author":"Nadri","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neuint.2009.06.002_bib21","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.neuroscience.2007.03.051","article-title":"Phenotypic characterization of spatial cognition and social behavior in mice with \u2018knockout\u2019 of the schizophrenia risk gene neuregulin 1","volume":"147","author":"O\u2019Tuathaigh","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuint.2009.06.002_bib22","series-title":"Repeatable Battery for the Assessment of Neuropsychological Status","author":"Randolph","year":"1998"},{"key":"10.1016\/j.neuint.2009.06.002_bib23","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1037\/0033-2909.133.5.833","article-title":"Neuropsychological impairments in schizophrenia: integration of performance-based and brain imaging findings","volume":"133","author":"Reichenberg","year":"2007","journal-title":"Psychol. Bull."},{"key":"10.1016\/j.neuint.2009.06.002_bib24","first-page":"101","article-title":"The semistructured BPRS interview and rating guide","volume":"24","author":"Rhoades","year":"1988","journal-title":"Psychopharmacol. Bull."},{"key":"10.1016\/j.neuint.2009.06.002_bib25","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1093\/hmg\/ddn351","article-title":"Disruption of the neurexin 1 gene is associated with schizophrenia","volume":"18","author":"Rujescu","year":"2009","journal-title":"Hum. Mol. Genet."},{"issue":"Suppl. 5","key":"10.1016\/j.neuint.2009.06.002_bib26","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s00406-008-5019-x","article-title":"Impact of neuregulin-1 on the pathophysiology of schizophrenia in human post-mortem studies","volume":"258","author":"Schmitt","year":"2008","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.neuint.2009.06.002_bib27","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1038\/sj.mp.4001994","article-title":"Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms","volume":"12","author":"Sei","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neuint.2009.06.002_bib28","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.neuint.2007.07.011","article-title":"Characterization of interactions between phencyclidine and amphetamine in rodent prefrontal cortex and striatum: implications in NMDA\/glycine-site-mediated dopaminergic dysregulation and dopamine transporter function","volume":"52","author":"Sershen","year":"2008","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neuint.2009.06.002_bib29","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.biopsych.2006.11.015","article-title":"Impact of schizophrenia candidate genes on schizotypy and cognitive endophenotypes at the population level","volume":"62","author":"Stefanis","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuint.2009.06.002_bib30","first-page":"2200","article-title":"Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans","volume":"118","author":"Tan","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neuint.2009.06.002_bib31","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.pharmthera.2009.02.004","article-title":"Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia","volume":"122","author":"Young","year":"2009","journal-title":"Pharmacol. Ther."}],"container-title":["Neurochemistry International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197018609001880?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197018609001880?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T17:16:06Z","timestamp":1685034966000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197018609001880"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":31,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["S0197018609001880"],"URL":"https:\/\/doi.org\/10.1016\/j.neuint.2009.06.002","relation":{},"ISSN":["0197-0186"],"issn-type":[{"value":"0197-0186","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}