{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T07:04:40Z","timestamp":1723014280080},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurochemistry International"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.neuint.2016.09.015","type":"journal-article","created":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T14:29:11Z","timestamp":1475332151000},"page":"22-29","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Relative expression of the p75 neurotrophin receptor, tyrosine receptor kinase A, and insulin receptor in SH-SY5Y neuroblastoma cells and hippocampi from Alzheimer's disease patients"],"prefix":"10.1016","volume":"101","author":[{"given":"Shingo","family":"Ito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"M\u00e9nard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trevor","family":"Atkinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Whitfield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Balu","family":"Chakravarthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuint.2016.09.015_bib2","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.neuron.2004.04.001","article-title":"p75NTR is positively promiscuous: novel partners and new insights","volume":"42","author":"Barker","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neuint.2016.09.015_bib3","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1042\/bj2450357","article-title":"Insulin receptor desensitization correlates with attenuation of tyrosine kinase activity, but not of receptor endocytosis","volume":"245","author":"Blake","year":"1987","journal-title":"Biochem. J."},{"key":"10.1016\/j.neuint.2016.09.015_bib4","doi-asserted-by":"crossref","DOI":"10.2174\/1872214810666160615102809","article-title":"Alterations in glucose metabolism in Alzheimer's disease","author":"Calsolaro","year":"2016","journal-title":"Recent Pat. Endocr. Metab. Immune Drug Discov."},{"key":"10.1016\/j.neuint.2016.09.015_bib5","doi-asserted-by":"crossref","first-page":"675","DOI":"10.3233\/JAD-2012-120115","article-title":"Hippocampal membrane-associated p75NTR levels are increased in Alzheimer's disease","volume":"30","author":"Chakravarthy","year":"2012","journal-title":"J.\u00a0Alzheimers Dis."},{"key":"10.1016\/j.neuint.2016.09.015_bib6","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/nrn1078","article-title":"Neurotrophins and their receptors: a convergence point for many signalling pathways","volume":"4","author":"Chao","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuint.2016.09.015_bib7","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.neurobiolaging.2003.09.001","article-title":"Synaptic slaughter in Alzheimer's disease","volume":"24","author":"Coleman","year":"2003","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neuint.2016.09.015_bib8","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1038\/sj.emboj.7601062","article-title":"An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation","volume":"25","author":"Costantini","year":"2006","journal-title":"EMBO J."},{"key":"10.1016\/j.neuint.2016.09.015_bib9","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1042\/BJ20050700","article-title":"A\u00a0TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging","volume":"391","author":"Costantini","year":"2005","journal-title":"Biochem. J."},{"key":"10.1016\/j.neuint.2016.09.015_bib10","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/jnen\/64.4.263","article-title":"The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease","volume":"64","author":"Counts","year":"2005","journal-title":"J.\u00a0Neuropathol. Exp. Neurol."},{"issue":"Suppl.\u00a02","key":"10.1016\/j.neuint.2016.09.015_bib11","first-page":"22","article-title":"Insulin and insulin-like growth factor I receptors: similarities and differences in signal transduction","volume":"55","author":"Dupont","year":"2001","journal-title":"Horm. Res."},{"key":"10.1016\/j.neuint.2016.09.015_bib12","doi-asserted-by":"crossref","first-page":"3315","DOI":"10.1096\/fj.09-132043","article-title":"Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease","volume":"23","author":"Freude","year":"2009","journal-title":"FASEB J."},{"key":"10.1016\/j.neuint.2016.09.015_bib13","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s007020050068","article-title":"Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease","volume":"105","author":"Frolich","year":"1998","journal-title":"J.\u00a0Neural Transm."},{"key":"10.1016\/j.neuint.2016.09.015_bib14","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1006\/exnr.2002.8018","article-title":"Increased p75(NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients","volume":"178","author":"Hu","year":"2002","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuint.2016.09.015_bib15","doi-asserted-by":"crossref","first-page":"493","DOI":"10.3233\/JAD-2012-120046","article-title":"Involvement of insulin-like growth factor 1 receptor signaling in the amyloid-beta peptide oligomers-induced p75 neurotrophin receptor protein expression in mouse Hippocampus","volume":"31","author":"Ito","year":"2012","journal-title":"J.\u00a0Alzheimers Dis."},{"key":"10.1016\/j.neuint.2016.09.015_bib16","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/0092-8674(86)90619-7","article-title":"Expression and structure of the human NGF receptor","volume":"47","author":"Johnson","year":"1986","journal-title":"Cell"},{"key":"10.1016\/j.neuint.2016.09.015_bib17","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1159\/000054694","article-title":"Improving influence of insulin on cognitive functions in humans","volume":"74","author":"Kern","year":"2001","journal-title":"Neuroendocrinology"},{"issue":"Suppl.\u00a01","key":"10.1016\/j.neuint.2016.09.015_bib18","first-page":"S49","article-title":"Synaptotoxic amyloid-beta oligomers: a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease?","volume":"33","author":"Klein","year":"2013","journal-title":"J.\u00a0Alzheimers Dis."},{"key":"10.1016\/j.neuint.2016.09.015_bib19","doi-asserted-by":"crossref","first-page":"10627","DOI":"10.1523\/JNEUROSCI.0620-09.2009","article-title":"The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in\u00a0vitro and in\u00a0vivo","volume":"29","author":"Knowles","year":"2009","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuint.2016.09.015_bib20","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0014-5793(98)00422-0","article-title":"Amyloidogenic determinant as a substrate recognition motif of insulin-degrading enzyme","volume":"427","author":"Kurochkin","year":"1998","journal-title":"FEBS Lett."},{"key":"10.1016\/j.neuint.2016.09.015_bib21","doi-asserted-by":"crossref","first-page":"18543","DOI":"10.1074\/jbc.M414112200","article-title":"Insulin stimulates postsynaptic density-95 protein translation via the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway","volume":"280","author":"Lee","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.neuint.2016.09.015_bib22","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0306-4522(00)00200-1","article-title":"Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons","volume":"99","author":"Lesort","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuint.2016.09.015_bib23","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/path.2912","article-title":"Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes","volume":"225","author":"Liu","year":"2011","journal-title":"J.\u00a0Pathol."},{"key":"10.1016\/j.neuint.2016.09.015_bib24","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.neurobiolaging.2008.04.002","article-title":"Defects in IGF-1 receptor, insulin receptor and IRS-1\/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling","volume":"31","author":"Moloney","year":"2010","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.neuint.2016.09.015_bib25","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/nature02319","article-title":"Sortilin is essential for proNGF-induced neuronal cell death","volume":"427","author":"Nykjaer","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.neuint.2016.09.015_bib26","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/j.cellsig.2004.03.017","article-title":"c-Cbl binds to tyrosine-phosphorylated neurotrophin receptor p75 and induces its ubiquitination","volume":"16","author":"Ohrt","year":"2004","journal-title":"Cell Signal"},{"key":"10.1016\/j.neuint.2016.09.015_bib27","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.tem.2005.01.008","article-title":"The role of insulin receptor signaling in the brain","volume":"16","author":"Plum","year":"2005","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.neuint.2016.09.015_bib28","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3233\/JAD-2005-8304","article-title":"Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine","volume":"8","author":"Rivera","year":"2005","journal-title":"J.\u00a0Alzheimers Dis."},{"key":"10.1016\/j.neuint.2016.09.015_bib29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0301-0082(02)00016-3","article-title":"Neurotrophin signaling through the p75 neurotrophin receptor","volume":"67","author":"Roux","year":"2002","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neuint.2016.09.015_bib30","doi-asserted-by":"crossref","first-page":"7084","DOI":"10.1523\/JNEUROSCI.23-18-07084.2003","article-title":"Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation","volume":"23","author":"Schubert","year":"2003","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuint.2016.09.015_bib31","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/s12032-013-0805-3","article-title":"Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer","volume":"31","author":"Singh","year":"2014","journal-title":"Med. Oncol."},{"key":"10.1016\/j.neuint.2016.09.015_bib32","doi-asserted-by":"crossref","first-page":"3941","DOI":"10.1523\/JNEUROSCI.0350-08.2008","article-title":"Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor","volume":"28","author":"Sotthibundhu","year":"2008","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuint.2016.09.015_bib33","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3233\/JAD-2005-7107","article-title":"Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease\u2013is this type 3 diabetes?","volume":"7","author":"Steen","year":"2005","journal-title":"J.\u00a0Alzheimers Dis."},{"key":"10.1016\/j.neuint.2016.09.015_bib34","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1172\/JCI59903","article-title":"Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline","volume":"122","author":"Talbot","year":"2012","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.neuint.2016.09.015_bib35","doi-asserted-by":"crossref","first-page":"5523","DOI":"10.1021\/acs.biochem.5b00805","article-title":"Structural dynamics of insulin receptor and transmembrane signaling","volume":"54","author":"Tatulian","year":"2015","journal-title":"Biochemistry"},{"key":"10.1016\/j.neuint.2016.09.015_bib36","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1002\/ana.410300410","article-title":"Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment","volume":"30","author":"Terry","year":"1991","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neuint.2016.09.015_bib37","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.pneurobio.2006.06.003","article-title":"Insulin signaling in the central nervous system: learning to survive","volume":"79","author":"van der Heide","year":"2006","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neuint.2016.09.015_bib38","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00401-015-1386-3","article-title":"Amyloid beta oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis","volume":"129","author":"Viola","year":"2015","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neuint.2016.09.015_bib39","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1111\/j.1471-4159.2006.04426.x","article-title":"A\u00a0beta oligomers - a decade of discovery","volume":"101","author":"Walsh","year":"2007","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neuint.2016.09.015_bib40","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1523\/JNEUROSCI.2733-10.2011","article-title":"p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain","volume":"31","author":"Wang","year":"2011","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuint.2016.09.015_bib41","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3390\/cells4030253","article-title":"The possible roles of the dentate granule Cell's leptin and other ciliary receptors in Alzheimer's neuropathology","volume":"4","author":"Whitfield","year":"2015","journal-title":"Cells"},{"key":"10.1016\/j.neuint.2016.09.015_bib42","doi-asserted-by":"crossref","first-page":"RC221","DOI":"10.1523\/JNEUROSCI.22-10-j0001.2002","article-title":"Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor","volume":"22","author":"Xie","year":"2002","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuint.2016.09.015_bib43","doi-asserted-by":"crossref","first-page":"18742","DOI":"10.1074\/jbc.M109.011015","article-title":"Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}","volume":"284","author":"Zhao","year":"2009","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.neuint.2016.09.015_bib44","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1111\/jnc.13076","article-title":"Amyloid beta-abrogated TrkA ubiquitination in PC12 cells analogous to Alzheimer's disease","volume":"133","author":"Zheng","year":"2015","journal-title":"J.\u00a0Neurochem."}],"container-title":["Neurochemistry International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197018616303485?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197018616303485?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T05:43:04Z","timestamp":1568439784000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197018616303485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":43,"alternative-id":["S0197018616303485"],"URL":"https:\/\/doi.org\/10.1016\/j.neuint.2016.09.015","relation":{},"ISSN":["0197-0186"],"issn-type":[{"value":"0197-0186","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relative expression of the p75 neurotrophin receptor, tyrosine receptor kinase A, and insulin receptor in SH-SY5Y neuroblastoma cells and hippocampi from Alzheimer's disease patients","name":"articletitle","label":"Article Title"},{"value":"Neurochemistry International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuint.2016.09.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}