{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:35:28Z","timestamp":1793140528410,"version":"4.5.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001352","name":"National University of Singapore","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["NUHSRO\/2017\/075\/PDF\/05"],"award-info":[{"award-number":["NUHSRO\/2017\/075\/PDF\/05"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["NMRC\/CSA\/CSA-SI\/007\/2016"],"award-info":[{"award-number":["NMRC\/CSA\/CSA-SI\/007\/2016"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002283","name":"Alzheimer\u2019s Research UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002283","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000320","name":"Alzheimer's Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000320","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["G0400074"],"award-info":[{"award-number":["G0400074"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurochemistry International"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.neuint.2021.105251","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T17:44:40Z","timestamp":1638294280000},"page":"105251","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Elevation of inactive cleaved annexin A1 in the neocortex is associated with amyloid, inflammatory and apoptotic markers in neurodegenerative dementias"],"prefix":"10.1016","volume":"152","author":[{"given":"Xin Ying","family":"Chua","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2869-0096","authenticated-orcid":false,"given":"Joyce R.","family":"Chong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai Ling","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasinda H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0022-5632","authenticated-orcid":false,"given":"Clive","family":"Ballard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dag","family":"Aarsland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8159-4469","authenticated-orcid":false,"given":"Paul T.","family":"Francis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7685-1424","authenticated-orcid":false,"given":"Mitchell K.P.","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuint.2021.105251_bib1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1177\/0891988704267470","article-title":"Are Parkinson's disease with dementia and dementia with Lewy bodies the same entity?","volume":"17","author":"Aarsland","year":"2004","journal-title":"J. Geriatr. Psychiatr. Neurol."},{"key":"10.1016\/j.neuint.2021.105251_bib2","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s004010100423","article-title":"Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease","volume":"103","author":"Augustinack","year":"2002","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neuint.2021.105251_bib3","doi-asserted-by":"crossref","first-page":"3687","DOI":"10.1038\/s41467-020-17491-z","article-title":"Gasdermin-D-dependent IL-1\u03b1 release from microglia promotes protective immunity during chronic Toxoplasma gondii infection","volume":"11","author":"Batista","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neuint.2021.105251_bib4","doi-asserted-by":"crossref","first-page":"24690","DOI":"10.1074\/jbc.M112.377101","article-title":"Annexin A1 interaction with the FPR2\/ALX receptor: identification of distinct domains and downstream associated signaling","volume":"287","author":"Bena","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuint.2021.105251_bib5","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological staging of Alzheimer-related changes","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neuint.2021.105251_bib6","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.jalz.2016.02.010","article-title":"Neuroinflammation in Alzheimer's disease: current evidence and future directions","volume":"12","author":"Calsolaro","year":"2016","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.neuint.2021.105251_bib7","doi-asserted-by":"crossref","first-page":"7193","DOI":"10.3390\/ijms14047193","article-title":"Distinct signaling cascades elicited by different formyl peptide receptor 2 (FPR2) agonists","volume":"14","author":"Cattaneo","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuint.2021.105251_bib8","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/bpa.12631","article-title":"Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration","volume":"29","author":"Chai","year":"2019","journal-title":"Brain Pathol."},{"key":"10.1016\/j.neuint.2021.105251_bib9","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1007\/s11064-015-1714-y","article-title":"Proteinase 3 induces neuronal cell death through microglial activation","volume":"40","author":"Cho","year":"2015","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.neuint.2021.105251_bib10","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3233\/JAD-160781","article-title":"Increased transforming growth factor \u03b22 in the neocortex of Alzheimer\u2019s disease and dementia with Lewy bodies is correlated with disease severity and soluble A\u03b242 load","volume":"56","author":"Chong","year":"2017","journal-title":"J. Alzheim. Dis."},{"key":"10.1016\/j.neuint.2021.105251_bib11","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13041-017-0316-9","article-title":"An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias","volume":"10","author":"Datta","year":"2017","journal-title":"Mol. Brain"},{"key":"10.1016\/j.neuint.2021.105251_bib12","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0014-5793(03)00570-2","article-title":"Annexin A1 processing is associated with caspase-dependent apoptosis in BZR cells","volume":"546","author":"Debret","year":"2003","journal-title":"FEBS (Fed. Eur. Biochem. Soc.) Lett."},{"key":"10.1016\/j.neuint.2021.105251_bib13","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1038\/ni.3503","article-title":"Interleukin 1\u03b1 and the inflammatory process","volume":"17","author":"Di Paolo","year":"2016","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.neuint.2021.105251_bib14","doi-asserted-by":"crossref","first-page":"e1580","DOI":"10.1212\/WNL.0000000000009240","article-title":"Total A\u03b242\/A\u03b240 ratio in plasma predicts amyloid-PET status, independent of clinical AD diagnosis","volume":"94","author":"Doecke","year":"2020","journal-title":"Neurology"},{"key":"10.1016\/j.neuint.2021.105251_bib15","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1002\/mds.21507","article-title":"Clinical diagnostic criteria for dementia associated with Parkinson's disease","volume":"22","author":"Emre","year":"2007","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neuint.2021.105251_bib16","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a033118","article-title":"Clinical neurology and epidemiology of the major neurodegenerative diseases","volume":"10","author":"Erkkinen","year":"2018","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"10.1016\/j.neuint.2021.105251_bib17","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/j.1365-2796.2005.01570.x","article-title":"Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease","volume":"258","author":"Fadeel","year":"2005","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.neuint.2021.105251_bib18","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-Mental State: a practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.neuint.2021.105251_bib19","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.neuroscience.2019.09.008","article-title":"Inflammatory and pro-resolving mediators in frontotemporal dementia and Alzheimer's disease","volume":"421","author":"Fraga","year":"2019","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuint.2021.105251_bib20","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/nrd.2016.39","article-title":"Resolution of inflammation: a new therapeutic frontier","volume":"15","author":"Fullerton","year":"2016","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.neuint.2021.105251_bib21","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.cell.2010.02.016","article-title":"Mechanisms underlying inflammation in neurodegeneration","volume":"140","author":"Glass","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.neuint.2021.105251_bib22","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1002\/mds.25048","article-title":"Brain amyloid and cognition in Lewy body diseases","volume":"27","author":"Gomperts","year":"2012","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neuint.2021.105251_bib23","doi-asserted-by":"crossref","first-page":"13432","DOI":"10.1074\/jbc.272.20.13432","article-title":"A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro","volume":"272","author":"Han","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuint.2021.105251_bib24","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/bpa.12182","article-title":"Regional multiple pathology scores are associated with cognitive decline in Lewy body dementias","volume":"25","author":"Howlett","year":"2015","journal-title":"Brain Pathol."},{"key":"10.1016\/j.neuint.2021.105251_bib25","doi-asserted-by":"crossref","first-page":"28176","DOI":"10.1074\/jbc.M803159200","article-title":"The ratio of monomeric to aggregated forms of A\u03b240 and A\u03b242 is an important determinant of amyloid-\u03b2 aggregation, fibrillogenesis, and toxicity","volume":"283","author":"Jan","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuint.2021.105251_bib26","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3389\/fncel.2020.00198","article-title":"Overview of general and discriminating markers of differential microglia phenotypes","volume":"14","author":"Jurga","year":"2020","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.neuint.2021.105251_bib27","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1136\/jnnp-2017-317134","article-title":"Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias","volume":"89","author":"King","year":"2018","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.neuint.2021.105251_bib28","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1749-6632.1999.tb07845.x","article-title":"Neurotoxicity and oxidative damage of beta amyloid 1-42 versus beta amyloid 1-40 in the mouse cerebral cortex","volume":"893","author":"Klein","year":"1999","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neuint.2021.105251_bib29","doi-asserted-by":"crossref","first-page":"3408","DOI":"10.1038\/emboj.2010.211","article-title":"Neurotoxicity of Alzheimer's disease Abeta peptides is induced by small changes in the Abeta42 to Abeta40 ratio","volume":"29","author":"Kuperstein","year":"2010","journal-title":"EMBO J."},{"key":"10.1016\/j.neuint.2021.105251_bib30","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3389\/fncel.2019.00430","article-title":"Loss of IL-10 promotes differentiation of microglia to a M1 phenotype","volume":"13","author":"Laffer","year":"2019","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.neuint.2021.105251_bib31","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1212\/01.wnl.0000256715.13907.d3","article-title":"DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers","volume":"68","author":"Lippa","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.neuint.2021.105251_bib32","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/bpa.12917","article-title":"Isoform-specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias","volume":"31","author":"Low","year":"2021","journal-title":"Brain Pathol."},{"key":"10.1016\/j.neuint.2021.105251_bib33","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/35040009","article-title":"Apoptosis in neurodegenerative disorders","volume":"1","author":"Mattson","year":"2000","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.neuint.2021.105251_bib34","doi-asserted-by":"crossref","first-page":"6317","DOI":"10.4049\/jimmunol.1001095","article-title":"Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia","volume":"185","author":"McArthur","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.neuint.2021.105251_bib35","doi-asserted-by":"crossref","DOI":"10.1212\/01.wnl.0000187889.17253.b1","article-title":"Diagnosis and management of dementia with Lewy bodies","volume":"65","author":"McKeith","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.neuint.2021.105251_bib36","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.41.4.479","article-title":"The Consortium to establish a Registry for Alzheimer's disease (CERAD)","volume":"41","author":"Mirra","year":"1991","journal-title":"Neurology"},{"key":"10.1016\/j.neuint.2021.105251_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00401-011-0910-3","article-title":"National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach","volume":"123","author":"Montine","year":"2012","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neuint.2021.105251_bib38","doi-asserted-by":"crossref","first-page":"4288","DOI":"10.1182\/blood-2010-02-270520","article-title":"Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature","volume":"116","author":"Pederzoli-Ribeil","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.neuint.2021.105251_bib39","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1186\/s12974-016-0692-6","article-title":"The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-beta peptide","volume":"13","author":"Ries","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.neuint.2021.105251_bib40","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19041045","article-title":"Annexin A1: uncovering the many talents of an old protein","volume":"19","author":"Sheikh","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuint.2021.105251_bib41","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/sj.bjp.0704054","article-title":"Transfection of AnxA1 in monocytic cells produced a high degree of spontaneous and stimulated apoptosis associated with caspase 3 activation","volume":"133","author":"Solito","year":"2001","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.neuint.2021.105251_bib42","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.tips.2007.12.003","article-title":"Annexin A1 in the brain - undiscovered roles?","volume":"29","author":"Solito","year":"2008","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.neuint.2021.105251_bib43","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8239258","article-title":"Annexin A1 and the resolution of inflammation: modulation of neutrophil recruitment, apoptosis, and clearance","author":"Sugimoto","year":"2016","journal-title":"J Immunol Res"},{"key":"10.1016\/j.neuint.2021.105251_bib44","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1016\/j.parkreldis.2015.10.009","article-title":"Neuroinflammation in Lewy body dementia","volume":"21","author":"Surendranathan","year":"2015","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.neuint.2021.105251_bib45","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1212\/WNL.58.12.1791","article-title":"Phases of A\u03b2-deposition in the human brain and its relevance for the development of AD","volume":"58","author":"Thal","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.neuint.2021.105251_bib46","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1189\/jlb.0112008","article-title":"Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis","volume":"92","author":"Vago","year":"2012","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.neuint.2021.105251_bib47","doi-asserted-by":"crossref","first-page":"29998","DOI":"10.1074\/jbc.M702876200","article-title":"Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3","volume":"282","author":"Vong","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuint.2021.105251_bib48","doi-asserted-by":"crossref","first-page":"232","DOI":"10.2174\/157015907782793667","article-title":"Anti-inflammatory and immune therapy for alzheimers disease: current status and future directions","volume":"5","author":"Walker","year":"2007","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.neuint.2021.105251_bib49","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s00401-015-1406-3","article-title":"Neuropathologically mixed Alzheimer's and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes","volume":"129","author":"Walker","year":"2015","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neuint.2021.105251_bib50","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1016\/S0140-6736(15)00462-6","article-title":"Lewy body dementias","volume":"386","author":"Walker","year":"2015","journal-title":"Lancet"},{"issue":"40\u201350","key":"10.1016\/j.neuint.2021.105251_bib51","first-page":"e41","article-title":"Resolution of inflammation is altered in Alzheimer's disease","volume":"11","author":"Wang","year":"2015","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.neuint.2021.105251_bib52","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0083-6729(06)74020-1","article-title":"Interleukins, inflammation, and mechanisms of Alzheimer's disease","author":"Weisman","year":"2006","journal-title":"Interleukins"},{"key":"10.1016\/j.neuint.2021.105251_bib53","first-page":"12","article-title":"Programmed cell death and its role in inflammation","volume":"2","author":"Yang","year":"2015","journal-title":"Mil Med Res"},{"key":"10.1016\/j.neuint.2021.105251_bib54","doi-asserted-by":"crossref","DOI":"10.1177\/1756286418791107","article-title":"Can inflammation be resolved in Alzheimer's disease?","volume":"11","author":"Zhu","year":"2018","journal-title":"Ther Adv Neurol Disord"}],"container-title":["Neurochemistry International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197018621002977?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197018621002977?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:42:13Z","timestamp":1777527733000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197018621002977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":54,"alternative-id":["S0197018621002977"],"URL":"https:\/\/doi.org\/10.1016\/j.neuint.2021.105251","relation":{},"ISSN":["0197-0186"],"issn-type":[{"value":"0197-0186","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elevation of inactive cleaved annexin A1 in the neocortex is associated with amyloid, inflammatory and apoptotic markers in neurodegenerative dementias","name":"articletitle","label":"Article Title"},{"value":"Neurochemistry International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuint.2021.105251","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105251"}}