{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:51:11Z","timestamp":1791953471547,"version":"4.3.4"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100015375","name":"The Affiliated Hospital of Southwest Medical University","doi-asserted-by":"publisher","award":["2022GLXNYDFY14"],"award-info":[{"award-number":["2022GLXNYDFY14"]}],"id":[{"id":"10.13039\/501100015375","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurochemistry International"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.neuint.2026.106249","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:57:17Z","timestamp":1787727437000},"page":"106249","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Recent insights on cell-type-specific lactylation driving neuropathic pain chronification"],"prefix":"10.1016","volume":"200","author":[{"given":"Zhengshan","family":"Qin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0249-7375","authenticated-orcid":false,"given":"Cehua","family":"Ou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s00011-026-02207-8","article-title":"Balancing inflammation and regeneration: immune cell dynamics in nerve repair: a comprehensive review","volume":"75","author":"Anjum","year":"2026","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.neuint.2026.106249_bib2","article-title":"Non-invasive in vivo bidirectional magnetogenetic modulation of pain circuits","author":"Antoniazzi","year":"2025","journal-title":"bioRxiv"},{"issue":"10","key":"10.1016\/j.neuint.2026.106249_bib3","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/s41593-020-0689-4","article-title":"A glycolytic shift in Schwann cells supports injured axons","volume":"23","author":"Babetto","year":"2020","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuint.2026.106249_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2026.02.032","article-title":"Oligodendrocyte-encoded lactate dehydrogenase A couples glycolysis to remyelination via protein lactylation","author":"Bao","year":"2026","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib5","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1038\/s41467-023-40349-z","article-title":"Neoadjuvant Afatinib for stage III EGFR-mutant non-small cell lung cancer: a phase II study","volume":"14","author":"Bian","year":"2023","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib6","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/s41392-024-02082-x","article-title":"Lactate and lactylation in cancer","volume":"10","author":"Chen","year":"2025","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib7","article-title":"Sox9 regulation of hexokinase 1 controls neuroinflammatory astrocyte subtypes in a rat model of neuropathic pain","volume":"16","author":"Chen","year":"2025","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.neuint.2026.106249_bib8","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3390\/brainsci15030294","article-title":"Lactylation and central nervous System diseases","volume":"15","author":"Chen","year":"2025","journal-title":"Brain Sci."},{"issue":"891","key":"10.1016\/j.neuint.2026.106249_bib9","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.adr9397","article-title":"Amphiregulin contributes to neuropathic pain by enhancing glycolysis that stimulates histone lactylation in sensory neurons","volume":"18","author":"Deng","year":"2025","journal-title":"Sci. Signal."},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1152\/physrev.00045.2019","article-title":"Neuropathic pain: from mechanisms to treatment","volume":"101","author":"Finnerup","year":"2021","journal-title":"Physiol. Rev."},{"issue":"2","key":"10.1016\/j.neuint.2026.106249_bib11","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3390\/cimb47020093","article-title":"NGF in neuropathic pain: understanding its role and therapeutic opportunities","volume":"47","author":"Garc\u00eda-Dom\u00ednguez","year":"2025","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.neuint.2026.106249_bib12","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1146\/annurev-pharmtox-051421-112259","article-title":"Neuropathic pain: mechanisms, sex differences, and potential therapies for a global problem","volume":"63","author":"Ghazisaeidi","year":"2023","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"issue":"4","key":"10.1016\/j.neuint.2026.106249_bib13","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1021\/acschemneuro.1c00841","article-title":"Epigenetic mechanisms of neural plasticity in chronic neuropathic pain","volume":"13","author":"Ghosh","year":"2022","journal-title":"ACS Chem. Neurosci."},{"issue":"20","key":"10.1016\/j.neuint.2026.106249_bib15","doi-asserted-by":"crossref","first-page":"3845","DOI":"10.1158\/0008-5472.CAN-21-4140","article-title":"Inhibition of EGFR overcomes acquired Lenvatinib resistance driven by STAT3-ABCB1 signaling in hepatocellular carcinoma","volume":"82","author":"Hu","year":"2022","journal-title":"Cancer Res."},{"key":"10.1016\/j.neuint.2026.106249_bib14","article-title":"Single-cell RNA-seq reveals distinct injury responses in different types of DRG sensory neurons","volume":"6","author":"Hu","year":"2016","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/j.neuint.2026.106249_bib16","doi-asserted-by":"crossref","first-page":"5529","DOI":"10.1093\/nar\/gkae183","article-title":"Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader","volume":"52","author":"Hu","year":"2024","journal-title":"Nucleic Acids Res."},{"issue":"6","key":"10.1016\/j.neuint.2026.106249_bib17","doi-asserted-by":"crossref","first-page":"4443","DOI":"10.1007\/s10753-025-02336-y","article-title":"RUNX1 induces central neuropathic pain by activating microglia and triggering the inflammatory response in spinal cord injury","volume":"48","author":"Huang","year":"2025","journal-title":"Inflammation"},{"issue":"10","key":"10.1016\/j.neuint.2026.106249_bib18","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1016\/j.pain.2011.06.017","article-title":"A new definition of neuropathic pain","volume":"152","author":"Jensen","year":"2011","journal-title":"Pain"},{"key":"10.1016\/j.neuint.2026.106249_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1087648","article-title":"Inflammation and histone modification in chronic pain","volume":"13","author":"Jiang","year":"2023","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpha.2025.101373","article-title":"Luteolin attenuates RA-associated chronic pain by targeting the LDHA\/H3K9la\/NFATC2 axis to suppress Th17 cell differentiation and central infiltration","volume":"16","author":"Jiang","year":"2026","journal-title":"J. Pharm. Anal."},{"issue":"7869","key":"10.1016\/j.neuint.2026.106249_bib21","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/s41586-021-03741-7","article-title":"EGFR activation limits the response of liver cancer to lenvatinib","volume":"595","author":"Jin","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.neuint.2026.106249_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2025.1546045","article-title":"Macrophage PKM2 depletion ameliorates hepatic inflammation and acute liver injury in mice","volume":"16","author":"Kang","year":"2025","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.neuint.2026.106249_bib23","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.jpain.2010.08.003","article-title":"Interleukin-17 contributes to neuroinflammation and neuropathic pain following peripheral nerve injury in mice","volume":"12","author":"Kim","year":"2011","journal-title":"J. Pain"},{"key":"10.1016\/j.neuint.2026.106249_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.861290","article-title":"Glycometabolism reprogramming of glial cells in central nervous system: novel target for neuropathic pain","volume":"13","author":"Kong","year":"2022","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib25","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12943-024-02008-9","article-title":"Positive feedback regulation between glycolysis and histone lactylation drives oncogenesis in pancreatic ductal adenocarcinoma","volume":"23","author":"Li","year":"2024","journal-title":"Mol. Cancer"},{"issue":"8036","key":"10.1016\/j.neuint.2026.106249_bib26","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1038\/s41586-024-07992-y","article-title":"AARS1 and AARS2 sense L-lactate to regulate cGAS as global lysine lactyltransferases","volume":"634","author":"Li","year":"2024","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib27","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s12943-025-02295-w","article-title":"Lactate accumulation induces H4K12la to activate super-enhancer-driven RAD23A expression and promote niraparib resistance in ovarian cancer","volume":"24","author":"Lu","year":"2025","journal-title":"Mol. Cancer"},{"issue":"7","key":"10.1016\/j.neuint.2026.106249_bib28","article-title":"Lactylation of histone H3k18 and Egr1 promotes endothelial glycocalyx degradation in sepsis-induced acute lung injury","volume":"12","author":"Lu","year":"2025","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.neuint.2026.106249_bib29","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.freeradbiomed.2025.09.049","article-title":"Cavidine alleviates paclitaxel-induced peripheral neuropathy by promoting mitochondrial autophagy through inhibiting PKM2-mediated histone lactylation","volume":"241","author":"Luo","year":"2025","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib30","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/s13148-023-01569-8","article-title":"A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain","volume":"15","author":"Maiar\u00f9","year":"2023","journal-title":"Clin. Epigenet."},{"issue":"23","key":"10.1016\/j.neuint.2026.106249_bib31","doi-asserted-by":"crossref","first-page":"3438","DOI":"10.1021\/acschemneuro.2c00440","article-title":"Sp1 inhibits PGC-1\u03b1 via HDAC2-Catalyzed histone deacetylation in chronic constriction injury-induced neuropathic pain","volume":"13","author":"Miao","year":"2022","journal-title":"ACS Chem. Neurosci."},{"issue":"3","key":"10.1016\/j.neuint.2026.106249_bib32","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/jnc.14998","article-title":"Down-regulation of microRNA-34c-5p alleviates neuropathic pain via the SIRT1\/STAT3 signaling pathway in rat models of chronic constriction injury of sciatic nerve","volume":"154","author":"Mo","year":"2020","journal-title":"J. Neurochem."},{"issue":"8","key":"10.1016\/j.neuint.2026.106249_bib33","doi-asserted-by":"crossref","DOI":"10.1111\/jnc.70179","article-title":"5-HT6 receptor inverse agonists modulate diabetic neuropathic pain in female rats: evidence for 5-HT6 receptor constitutive activity","volume":"169","author":"Mokhtar","year":"2025","journal-title":"J. Neurochem."},{"issue":"3","key":"10.1016\/j.neuint.2026.106249_bib34","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abi6696","article-title":"Class I histone deacetylases (HDAC1-3) are histone lysine delactylases","volume":"8","author":"Moreno-Yruela","year":"2022","journal-title":"Sci. Adv."},{"issue":"12","key":"10.1016\/j.neuint.2026.106249_bib35","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1021\/acschembio.4c00248","article-title":"The TRIM33 bromodomain recognizes histone lysine lactylation","volume":"19","author":"Nu\u00f1ez","year":"2024","journal-title":"ACS Chem. Biol."},{"issue":"24","key":"10.1016\/j.neuint.2026.106249_bib36","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242417143","article-title":"The epigenetics of neuropathic pain: a systematic update","volume":"24","author":"Peth\u0151","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.neuint.2026.106249_bib37","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1093\/brain\/awac266","article-title":"RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain","volume":"146","author":"Ray","year":"2023","journal-title":"Brain"},{"key":"10.1016\/j.neuint.2026.106249_bib39","article-title":"Dorsal root ganglion-targeted analgesic delivery for effective relief of neuropathic pain","volume":"33","author":"Sun","year":"2025","journal-title":"Mater. Today Bio"},{"issue":"21","key":"10.1016\/j.neuint.2026.106249_bib38","article-title":"Glycolysis-derived lactate induces ACSL4 expression and lactylation to activate ferroptosis during intervertebral disc degeneration","volume":"12","author":"Sun","year":"2025","journal-title":"Adv. Sci. (Weinh.)"},{"issue":"4","key":"10.1016\/j.neuint.2026.106249_bib40","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.pain.2013.11.013","article-title":"Neuropathic pain in the general population: a systematic review of epidemiological studies","volume":"155","author":"van Hecke","year":"2014","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib42","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/s41420-025-02381-4","article-title":"Lactylation: a promising therapeutic target in ischemia-reperfusion injury management","volume":"11","author":"Wang","year":"2025","journal-title":"Cell Death Discov."},{"issue":"12","key":"10.1016\/j.neuint.2026.106249_bib41","doi-asserted-by":"crossref","first-page":"755","DOI":"10.3390\/metabo15120755","article-title":"The crosstalk between brain energy metabolism and neuropathic pain: mechanisms and therapeutic implications","volume":"15","author":"Wang","year":"2025","journal-title":"Metabolites"},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib43","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.0365-25.2025","article-title":"Histone lactylation contributes to neuropathic pain by facilitating m6A reader protein IGF2BP2 expression in DRG sensory neurons","volume":"46","author":"Wang","year":"2026","journal-title":"J. Neurosci."},{"issue":"7","key":"10.1016\/j.neuint.2026.106249_bib44","article-title":"Decoding lactylation in neuropathic pain: immune cell infiltration patterns and machine learning-identified candidate biomarkers","volume":"105","author":"Wu","year":"2026","journal-title":"Medicine (Baltim.)"},{"key":"10.1016\/j.neuint.2026.106249_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.neo.2024.100973","article-title":"FBXO38 deficiency promotes lysosome-dependent STING degradation and inhibits cGAS-STING pathway activation","volume":"49","author":"Wu","year":"2024","journal-title":"Neoplasia"},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib46","doi-asserted-by":"crossref","DOI":"10.1080\/08916934.2024.2384889","article-title":"LDHA-Induced histone lactylation mediates the development of osteoarthritis through regulating the transcription activity of TPI1 gene","volume":"57","author":"Xia","year":"2024","journal-title":"Autoimmunity"},{"key":"10.1016\/j.neuint.2026.106249_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fnana.2023.1162049","article-title":"Single-cell transcriptomic profiling of dorsal root ganglion: an overview","volume":"17","author":"Xie","year":"2023","journal-title":"Front. Neuroanat."},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib48","doi-asserted-by":"crossref","first-page":"7165","DOI":"10.1038\/s41467-025-62343-3","article-title":"Histone lactylation regulates DOCK4 to control heat nociception and supports Dynein-mediated Nav1.7 trafficking","volume":"16","author":"Xie","year":"2025","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.neuint.2026.106249_bib49","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0301352","article-title":"Neuropathic pain in patients with osteoarthritis of the hip before and after total hip arthroplasty","volume":"19","author":"Yamabe","year":"2024","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib50","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/s41418-021-00841-9","article-title":"Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis","volume":"29","author":"Yang","year":"2022","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.neuint.2026.106249_bib51","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.bbi.2025.04.016","article-title":"CMPK2 facilitates pain sensitization by promoting the lactylation and deactivation of cGAS-STING pathway in neuropathic pain","volume":"128","author":"Yang","year":"2025","journal-title":"Brain Behav. Immun."},{"issue":"38","key":"10.1016\/j.neuint.2026.106249_bib52","article-title":"Inhibition of lactylation by LRP1 expression increases the risk of intervertebral disc degeneration: a multi-omics summary-based mendelian randomization analysis","volume":"104","author":"Yang","year":"2025","journal-title":"Medicine (Baltim.)"},{"issue":"37","key":"10.1016\/j.neuint.2026.106249_bib53","article-title":"Uncovering potential drug targets for lactylation-related genes mediated intervertebral disc degeneration: a Mendelian randomization analysis integrating eQTL data","volume":"104","author":"Yang","year":"2025","journal-title":"Medicine (Baltim.)"},{"key":"10.1016\/j.neuint.2026.106249_bib54","doi-asserted-by":"crossref","first-page":"799","DOI":"10.34133\/research.0799","article-title":"Lactylation of mitochondrial adenosine triphosphate synthase subunit alpha regulates vascular remodeling and progression of aortic dissection","volume":"8","author":"Yu","year":"2025","journal-title":"Research"},{"issue":"50","key":"10.1016\/j.neuint.2026.106249_bib55","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2421496121","article-title":"DPF2 reads histone lactylation to drive transcription and tumorigenesis","volume":"121","author":"Zhai","year":"2024","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"7779","key":"10.1016\/j.neuint.2026.106249_bib56","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/s41586-019-1678-1","article-title":"Metabolic regulation of gene expression by histone lactylation","volume":"574","author":"Zhang","year":"2019","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib58","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1186\/s12974-024-03185-6","article-title":"Lactylation of histone by BRD4 regulates astrocyte polarization after experimental subarachnoid hemorrhage","volume":"21","author":"Zhang","year":"2024","journal-title":"J. Neuroinflammation"},{"issue":"9","key":"10.1016\/j.neuint.2026.106249_bib57","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/s41422-023-00844-w","article-title":"\u03b1-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure","volume":"33","author":"Zhang","year":"2023","journal-title":"Cell Res."},{"issue":"5","key":"10.1016\/j.neuint.2026.106249_bib59","doi-asserted-by":"crossref","DOI":"10.1111\/cns.14745","article-title":"Histone deacetylase as emerging pharmacological therapeutic target for neuropathic pain: from epigenetic to selective drugs","volume":"30","author":"Zhang","year":"2024","journal-title":"CNS Neurosci. Ther."},{"issue":"1","key":"10.1016\/j.neuint.2026.106249_bib60","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1186\/s10020-024-00924-6","article-title":"Pentagalloylglucose alleviates acetaminophen-induced acute liver injury by modulating inflammation via cGAS-STING pathway","volume":"30","author":"Zheng","year":"2024","journal-title":"Mol. Med. (Tokyo)"},{"issue":"9","key":"10.1016\/j.neuint.2026.106249_bib61","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1016\/j.cmet.2024.05.016","article-title":"Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation","volume":"36","author":"Zhou","year":"2024","journal-title":"Cell Metab."},{"issue":"10","key":"10.1016\/j.neuint.2026.106249_bib62","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1016\/j.cell.2024.04.002","article-title":"Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis","volume":"187","author":"Zong","year":"2024","journal-title":"Cell"}],"container-title":["Neurochemistry International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197018626001403?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0197018626001403?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:36:03Z","timestamp":1791952563000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0197018626001403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":62,"alternative-id":["S0197018626001403"],"URL":"https:\/\/doi.org\/10.1016\/j.neuint.2026.106249","relation":{},"ISSN":["0197-0186"],"issn-type":[{"value":"0197-0186","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recent insights on cell-type-specific lactylation driving neuropathic pain chronification","name":"articletitle","label":"Article Title"},{"value":"Neurochemistry International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuint.2026.106249","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106249"}}