{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T07:34:23Z","timestamp":1769240063514,"version":"3.49.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1016\/j.neulet.2005.01.027","type":"journal-article","created":{"date-parts":[[2005,2,4]],"date-time":"2005-02-04T07:12:48Z","timestamp":1107501168000},"page":"48-53","source":"Crossref","is-referenced-by-count":42,"title":["The administration of cobra venom factor reduces post-ischemic cerebral injury in adult and neonatal rats"],"prefix":"10.1016","volume":"380","author":[{"given":"Estuardo","family":"Figueroa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura E.","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela W.","family":"Feldhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert A.","family":"Lassiter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2005.01.027_bib1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1227\/01.NEU.0000043710.61233.B4","article-title":"Protective effect of C1 esterase inhibitor on reperfusion injury in the rat middle cerebral artery occlusion model","volume":"52","author":"Akita","year":"2003","journal-title":"Neurosurgery"},{"key":"10.1016\/j.neulet.2005.01.027_bib2","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/00024382-200405000-00002","article-title":"The role of the complement system in ischemia-reperfusion injury","volume":"21","author":"Arumugam","year":"2004","journal-title":"Shock"},{"key":"10.1016\/j.neulet.2005.01.027_bib3","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1161\/01.STR.27.9.1616","article-title":"Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model","volume":"27","author":"Belayev","year":"1996","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2005.01.027_bib4","doi-asserted-by":"crossref","first-page":"9459","DOI":"10.1523\/JNEUROSCI.23-28-09459.2003","article-title":"Complement activation contributes to hypoxic\u2013ischemic brain injury in neonatal rats","volume":"23","author":"Cowell","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2005.01.027_bib5","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1016\/S0002-9440(10)63744-3","article-title":"The powerful neuroprotective action of C1-inhibitor on brain ischemia-reperfusion injury does not require C1q","volume":"164","author":"De Simoni","year":"2004","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.neulet.2005.01.027_bib6","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/00004647-200302000-00010","article-title":"Neuroprotection by complement (C1) inhibitor in mouse transient brain ischemia","volume":"23","author":"De Simoni","year":"2003","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neulet.2005.01.027_bib7","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.molimm.2004.03.013","article-title":"Initiation of complement activation following oxidative stress. In vitro and in vivo observations","volume":"41","author":"Hart","year":"2004","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.neulet.2005.01.027_bib8","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1084\/jem.133.4.885","article-title":"The phlogistic role of C3 leukotactic fragments in myocardial infarcts of rats","volume":"133","author":"Hill","year":"1971","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.neulet.2005.01.027_bib9","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1126\/science.285.5427.595","article-title":"Neuronal protection in stroke by an sLex-glycosylated complement inhibitory protein","volume":"285","author":"Huang","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.neulet.2005.01.027_bib10","first-page":"352A","article-title":"In neonatal rats, the complement inhibitors sCR1 and sCR1-sLex do not reduce the volume of hypoxic\u2013ischemic (HI) cerebral infarction","volume":"49","author":"Imm","year":"2001","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.neulet.2005.01.027_bib11","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1084\/jem.194.11.1609","article-title":"Complement 1 inhibitor is a regulator of the alternative complement pathway","volume":"194","author":"Jiang","year":"2001","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.neulet.2005.01.027_bib12","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1358\/mf.2003.25.8.778081","article-title":"Novel complement C1 inhibitor BSF468248 does not improve brain damage after cortical vein occlusion","volume":"25","author":"Kaido","year":"2003","journal-title":"Methods Find. Exp. Clin. Pharmacol."},{"key":"10.1016\/j.neulet.2005.01.027_bib13","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.clp.2004.03.005","article-title":"The role of complement in neonatal hypoxic\u2013ischemic cerebral injury","volume":"31","author":"Lassiter","year":"2004","journal-title":"Clin. Perinatol."},{"key":"10.1016\/j.neulet.2005.01.027_bib14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0304-3940(01)01653-6","article-title":"Complement inhibition does not reduce post-hypoxic\u2013ischemic cerebral injury in 21-day-old rats","volume":"302","author":"Lassiter","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neulet.2005.01.027_bib15","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1203\/00006450-199707000-00020","article-title":"The administration of complement component C9 enhances the survival of neonatal rats with Escherichia coli sepsis","volume":"42","author":"Lassiter","year":"1997","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.neulet.2005.01.027_bib16","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1203\/00006450-199404000-00003","article-title":"Supplemental complement component C9 enhances the capacity of neonatal serum to kill multiple isolates of pathogenic Escherichia coli","volume":"35","author":"Lassiter","year":"1994","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.neulet.2005.01.027_bib17","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0361-9230(99)00004-0","article-title":"Complement depletion does not reduce brain injury in a rabbit model of thromboembolic stroke","volume":"48","author":"Lew","year":"1999","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.neulet.2005.01.027_bib18","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1002\/ana.410400408","article-title":"Complement activation in the central nervous system following blood\u2013brain barrier damage in man","volume":"40","author":"Lindsberg","year":"1996","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neulet.2005.01.027_bib19","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1034\/j.1399-3089.2001.00074.x","article-title":"Preconditioning with the prostacyclin analog epoprostenol and cobra venom factor prevents reperfusion injury and hyperacute rejection in discordant liver xenotransplantation","volume":"8","author":"Meyer","year":"2001","journal-title":"Xenotransplantation"},{"key":"10.1016\/j.neulet.2005.01.027_bib20","series-title":"The Complement System","first-page":"483","article-title":"Therapeutic manipulation of the complement system","author":"Mollnes","year":"2004"},{"key":"10.1016\/j.neulet.2005.01.027_bib21","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0161-5890(03)00111-1","article-title":"Complement therapeutics; history and current progress","volume":"40","author":"Morgan","year":"2003","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.neulet.2005.01.027_bib22","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1203\/00006450-199005000-00007","article-title":"Cerebral blood flow and edema in perinatal hypoxic\u2013ischemic brain damage","volume":"27","author":"Mujsce","year":"1990","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.neulet.2005.01.027_bib23","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic\u2013ischemic brain damage in the rat","volume":"9","author":"Rice","year":"1981","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neulet.2005.01.027_bib24","doi-asserted-by":"crossref","first-page":"11237","DOI":"10.1074\/jbc.274.16.11237","article-title":"Recombinant glycoproteins that inhibit complement activation and also bind the selectin adhesion molecules","volume":"274","author":"Rittershaus","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neulet.2005.01.027_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neulet.2004.12.008","article-title":"Complement component 9 activation, consumption, and neuronal deposition in the post-hypoxic\u2013ischemic central nervous system of human newborn infants","volume":"378","author":"Schultz","year":"2005","journal-title":"Neurosci. Lett."},{"issue":"Suppl.","key":"10.1016\/j.neulet.2005.01.027_bib26","first-page":"383","article-title":"Lung injury secondary to chemotactic factor-induced leukocyte activation","volume":"12","author":"Till","year":"1983","journal-title":"Agents Actions"},{"key":"10.1016\/j.neulet.2005.01.027_bib27","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1159\/000244036","article-title":"Effect of unilateral perinatal hypoxic\u2013ischemic brain damage on the gross development of opposite cerebral hemisphere","volume":"65","author":"Towfighi","year":"1994","journal-title":"Biol. Neonate"},{"key":"10.1016\/j.neulet.2005.01.027_bib28","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/(SICI)1098-1136(200007)31:1<39::AID-GLIA40>3.0.CO;2-1","article-title":"Glial responses, clusterin, and complement in permanent focal cerebral ischemia in the mouse","volume":"31","author":"Van Beek","year":"2000","journal-title":"Glia"},{"key":"10.1016\/j.neulet.2005.01.027_bib29","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1161\/01.STR.19.2.245","article-title":"Regional cerebral blood flow during hypoxia\u2013ischemia in immature rats","volume":"19","author":"Vannucci","year":"1988","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2005.01.027_bib30","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0361-9230(97)00408-5","article-title":"Complement depletion improves neurological function in cerebral ischemia","volume":"45","author":"Vasthare","year":"1998","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.neulet.2005.01.027_bib31","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.molimm.2004.03.011","article-title":"Recombinant cobra venom factor","volume":"41","author":"Vogel","year":"2004","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.neulet.2005.01.027_bib32","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1056\/NEJM200104053441406","article-title":"First of two parts","volume":"344","author":"Walport","year":"2001","journal-title":"N. Engl. J Med."},{"key":"10.1016\/j.neulet.2005.01.027_bib33","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0165-0270(98)00067-3","article-title":"Quantification of infarct size on focal cerebral ischemia model of rats using a simple and economical method","volume":"84","author":"Yang","year":"1998","journal-title":"J. Neurosci. Methods"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394005000200?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394005000200?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,29]],"date-time":"2019-01-29T18:30:05Z","timestamp":1548786605000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394005000200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":33,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["S0304394005000200"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2005.01.027","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2005,5]]}}}