{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T07:45:48Z","timestamp":1769499948670,"version":"3.49.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2006,2,1]],"date-time":"2006-02-01T00:00:00Z","timestamp":1138752000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2006,2]]},"DOI":"10.1016\/j.neulet.2005.10.040","type":"journal-article","created":{"date-parts":[[2005,11,19]],"date-time":"2005-11-19T07:15:24Z","timestamp":1132384524000},"page":"168-173","source":"Crossref","is-referenced-by-count":23,"title":["G-CSF protects human cerebral hybrid neurons against in vitro ischemia"],"prefix":"10.1016","volume":"394","author":[{"given":"Keun-Hwa","family":"Jung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kon","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon-Tae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lami","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung U.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Kyu","family":"Roh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2005.10.040_bib1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0306-4522(01)00268-8","article-title":"Stroke induces widespread changes of gene expression for glial cell line-derived neurotrophic factor family receptors in the adult rat brain","volume":"106","author":"Arvidsson","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.neulet.2005.10.040_bib2","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1172\/JCI115107","article-title":"In vitro and in vivo activation of endothelial cells by colony-stimulating factors","volume":"87","author":"Bussolino","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neulet.2005.10.040_bib3","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/1043-4666(93)90047-9","article-title":"The hematopoietin receptor superfamily","volume":"5","author":"Cosman","year":"1993","journal-title":"Cytokine"},{"key":"10.1016\/j.neulet.2005.10.040_bib4","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1097\/00001756-200208070-00020","article-title":"Human neural stem cells: electrophysiological properties of voltage-gated ion channels","volume":"13","author":"Cho","year":"2002","journal-title":"Neuroreport"},{"key":"10.1016\/j.neulet.2005.10.040_bib5","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1749-6632.1997.tb48638.x","article-title":"Role of apoptotic proteins in ischemic hippocampal damage","volume":"835","author":"Davis","year":"1997","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.neulet.2005.10.040_bib6","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/ana.10407","article-title":"New perspectives on developing acute stroke therapy","volume":"53","author":"Fisher","year":"2003","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neulet.2005.10.040_bib7","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S1074-7613(00)80501-4","article-title":"Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis","volume":"5","author":"Fukada","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/j.neulet.2005.10.040_bib8","doi-asserted-by":"crossref","first-page":"4959","DOI":"10.1097\/00001756-200404090-00022","article-title":"VEGF protects human cerebral hybrid neurons from in vitro ischemia","volume":"15","author":"Han","year":"2004","journal-title":"Neuroreport"},{"key":"10.1016\/j.neulet.2005.10.040_bib9","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/00062752-199805000-00013","article-title":"Anti-inflammatory effects of granulocyte colony-stimulating factor","volume":"5","author":"Hartung","year":"1998","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.neulet.2005.10.040_bib10","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/377591a0","article-title":"Cytokine receptor signaling","volume":"377","author":"Ihle","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.neulet.2005.10.040_bib11","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0092-8674(00)81277-5","article-title":"STATs: signal transducers and activators of transcription","volume":"84","author":"Ihle","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.neulet.2005.10.040_bib12","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1161\/01.STR.0000083698.20199.1F","article-title":"Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage","volume":"34","author":"Jeong","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2005.10.040_bib13","doi-asserted-by":"crossref","first-page":"10242","DOI":"10.1073\/pnas.97.18.10242","article-title":"Vascular endothelial growth factor: direct neuroprotective effect in vitro ischemia","volume":"97","author":"Jin","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neulet.2005.10.040_bib14","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1097\/00004647-199911000-00006","article-title":"Evidence for neuroprotective effects of endogenous brain-derived neurotrophic factor after global forebrain ischemia in rats","volume":"19","author":"Larsson","year":"1999","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neulet.2005.10.040_bib15","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1523\/JNEUROSCI.06-02-00514.1986","article-title":"Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins","volume":"6","author":"Lee","year":"1986","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neulet.2005.10.040_bib16","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0278-5846(03)00022-8","article-title":"Apoptosis and brain ischaemia","volume":"27","author":"Love","year":"2003","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.neulet.2005.10.040_bib17","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1089\/neu.2000.17.899","article-title":"Apoptosis after experimental stroke: fact or fashion?","volume":"17","author":"MacManus","year":"2000","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.neulet.2005.10.040_bib18","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1006\/nbdi.2002.0501","article-title":"Generation and characterization of human hybrid neurons produced between embryonic CNS neurons and neuroblastoma cells","volume":"11","author":"Nagai","year":"2002","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neulet.2005.10.040_bib19","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/ni813","article-title":"G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4","volume":"3","author":"Petit","year":"2002","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.neulet.2005.10.040_bib20","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/sj.cdd.4400476","article-title":"Emerging roles of caspase-3 in apoptosis","volume":"6","author":"Porter","year":"1999","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.neulet.2005.10.040_bib21","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1161\/01.STR.32.5.1226","article-title":"Delayed neuroprotective effect of insulin-like growth factor-I after experimental transient focal cerebral ischemia monitored with MRI","volume":"32","author":"Sch\u00e4bitz","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2005.10.040_bib22","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1161\/01.STR.0000057814.70180.17","article-title":"Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia","volume":"34","author":"Sch\u00e4bitz","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2005.10.040_bib23","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1172\/JCI23559","article-title":"The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis","volume":"115","author":"Schneider","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neulet.2005.10.040_bib24","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/S0165-0173(99)00013-2","article-title":"Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors","volume":"30","author":"Semkova","year":"1999","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.neulet.2005.10.040_bib25","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0014-2999(02)02785-1","article-title":"Beneficial effect of pharmacological mobilization of bone marrow in experimental cerebral ischemia","volume":"458","author":"Six","year":"2003","journal-title":"Eur. J. Pharmacol."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394005011973?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394005011973?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,6]],"date-time":"2019-04-06T11:37:58Z","timestamp":1554550678000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394005011973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["S0304394005011973"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2005.10.040","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2006,2]]}}}