{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:26:49Z","timestamp":1785796009520,"version":"3.56.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1016\/j.neulet.2006.07.040","type":"journal-article","created":{"date-parts":[[2006,8,10]],"date-time":"2006-08-10T11:36:00Z","timestamp":1155209760000},"page":"133-137","source":"Crossref","is-referenced-by-count":57,"title":["The 196G\/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder"],"prefix":"10.1016","volume":"406","author":[{"given":"Palmiero","family":"Monteleone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Zanardini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Tortorella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Gennarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eloisa","family":"Castaldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetta","family":"Canestrelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Maj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2006.07.040_bib1","series-title":"BMDP Statistical Software","year":"1985"},{"key":"10.1016\/j.neulet.2006.07.040_bib2","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1001\/archpsyc.60.8.804","article-title":"Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in post-mortem brain of suicide subjects","volume":"60","author":"Dwivedi","year":"2003","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neulet.2006.07.040_bib3","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0092-8674(03)00035-7","article-title":"The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function","volume":"112","author":"Egan","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.neulet.2006.07.040_bib4","series-title":"Structured clinical interview for DSM-IV axis I disorders SCID-I","year":"1995"},{"key":"10.1016\/j.neulet.2006.07.040_bib5","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/ajmg.b.30090","article-title":"Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association study in patients with obesity, eating disorders, and attention-deficit\/hyperactivity disorder","volume":"132","author":"Friedel","year":"2005","journal-title":"Am. J. Med. Genet. Part B Neuropsychiat. Genet."},{"key":"10.1016\/j.neulet.2006.07.040_bib6","series-title":"Clinical Handbook of Eating Disorders\u2014An Integrated Approach","first-page":"323","article-title":"Molecular biology of anorexia nervosa, bulimia nervosa, binge eating disorder, and obesity","author":"Grice","year":"2004"},{"issue":"150","key":"10.1016\/j.neulet.2006.07.040_bib7","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1192\/bjp.150.1.18","article-title":"A self-rating scale for bulimia: the BITE","volume":"150","author":"Henderson","year":"1987","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.neulet.2006.07.040_bib8","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1093\/emboj\/19.6.1290","article-title":"BDNF regulates eating behavior and locomotor activity in mice","volume":"19","author":"Kernie","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.neulet.2006.07.040_bib9","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/ajmg.b.20153","article-title":"Association between the brain-derived neurotrophic factor 196G\/A polymorphism and eating disorders","volume":"127","author":"Koizumi","year":"2004","journal-title":"Am J. Med. Genet. B Neuropsychiat. Genet."},{"key":"10.1016\/j.neulet.2006.07.040_bib10","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev.ne.19.030196.001445","article-title":"Physiology of neurotrophins","volume":"19","author":"Lewin","year":"1996","journal-title":"Ann. Rev. Neurosci."},{"key":"10.1016\/j.neulet.2006.07.040_bib11","first-page":"182","article-title":"Neurotrophic factors: from molecule to man","volume":"17","author":"Lindsay","year":"1994","journal-title":"T.I.N.S."},{"key":"10.1016\/j.neulet.2006.07.040_bib12","doi-asserted-by":"crossref","first-page":"15239","DOI":"10.1073\/pnas.96.26.15239","article-title":"Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities","volume":"96","author":"Lyons","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neulet.2006.07.040_bib13","doi-asserted-by":"crossref","first-page":"436","DOI":"10.2337\/diabetes.49.3.436","article-title":"Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice","volume":"49","author":"Nagakawa","year":"2000","journal-title":"Diabetes"},{"key":"10.1016\/j.neulet.2006.07.040_bib14","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1086\/342288","article-title":"The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study","volume":"71","author":"Neves-Pereira","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.neulet.2006.07.040_bib15","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1155\/EDR.2001.201","article-title":"Brain-derived neurotrophic factor regulates energy expenditure through the central nervous system in obese diabetic mice","volume":"2","author":"Nonomura","year":"2001","journal-title":"Int. J. Exp. Diabetes Res."},{"key":"10.1016\/j.neulet.2006.07.040_bib16","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1093\/hmg\/ddh137","article-title":"Association of BDNF with anorexia nervosa, bulimia and age of onset of weight loss in six European populations","volume":"13","author":"Ribas\u00e9s","year":"2004","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neulet.2006.07.040_bib17","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1210\/me.15.10.1748","article-title":"Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity","volume":"15","author":"Rios","year":"2001","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.neulet.2006.07.040_bib18","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0166-4328(00)00364-8","article-title":"Physical activity-antidepressant treatment combination: Impact on brain-derived neurotrophic factor and behaviour in an animal model","volume":"120","author":"Russo-Neustadt","year":"2001","journal-title":"Behav. Brain. Res."},{"key":"10.1016\/j.neulet.2006.07.040_bib19","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/ajmg.b.20118","article-title":"Ethnic difference of the BDNF 196G\/A (val66met) polymorphism frequencies: the possibility to explain ethnic mental traits","volume":"126","author":"Shimizu","year":"2004","journal-title":"Am. J. Med. Genet. B Neuropsychiat. Genet."},{"key":"10.1016\/j.neulet.2006.07.040_bib20","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1038\/sj.ijo.0801678","article-title":"Acute effects of brain-derived neurotrophic factor on energy expenditure in obese diabetic mice","volume":"25","author":"Tsuchida","year":"2001","journal-title":"Int. J. Obes. Rel. Metab. Disord."},{"key":"10.1016\/j.neulet.2006.07.040_bib21","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1086\/430507","article-title":"Rational inferences about departures from Hardy\u2013Weinberg equilibrium","volume":"76","author":"Wittke-Thompson","year":"2005","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.neulet.2006.07.040_bib22","series-title":"Obesity: Preventing and Managing the Global Epidemic: Report of a WHO Consultation on Obesity (WHO\/NUT\/NCD)","author":"World Health Organization","year":"1998"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394006007385?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394006007385?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T11:22:27Z","timestamp":1547464947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394006007385"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":22,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["S0304394006007385"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2006.07.040","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2006,10]]}}}