{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T21:22:40Z","timestamp":1769203360172,"version":"3.49.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1016\/j.neulet.2006.10.024","type":"journal-article","created":{"date-parts":[[2007,2,6]],"date-time":"2007-02-06T12:56:16Z","timestamp":1170766576000},"page":"5-9","source":"Crossref","is-referenced-by-count":33,"title":["Edaravone inhibits lipid peroxidation in neonatal hypoxic-ischemic rats: An in vivo microdialysis study"],"prefix":"10.1016","volume":"414","author":[{"given":"Jesmin I.","family":"Noor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuto","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoaki","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuyomu","family":"Ikenoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2006.10.024_bib1","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0006-291X(86)80217-0","article-title":"A search for oxygen-centered free radicals in the lipoxygenase\/linoleic acid system","volume":"141","author":"Connor","year":"1986","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.neulet.2006.10.024_bib2","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1159\/000047088","article-title":"Free radicals and brain damage in the newborn","volume":"79","author":"Giuseppe","year":"2001","journal-title":"Biol. Neonate"},{"key":"10.1016\/j.neulet.2006.10.024_bib3","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1021\/tx00023a005","article-title":"High-performance liquid chromatography with electrochemical detection for determination of the major malonaldehyde-guanine adduct","volume":"4","author":"Goda","year":"1991","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.neulet.2006.10.024_bib4","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/0003-9861(86)90305-X","article-title":"Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts","volume":"246","author":"Halliwell","year":"1986","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.neulet.2006.10.024_bib5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0304-3940(02)00573-6","article-title":"Effect of the free radical scavenger, 3-methyl-1phenyl-2pyrazolin-5-one (MCI-186), on hypoxia-ischemia-induced brain injury in neonatal rats","volume":"329","author":"Ikeda","year":"2002","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neulet.2006.10.024_bib6","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1093\/clinchem\/34.12.2433","article-title":"Specificity of the thiobarbituric acid reaction: its use in studies of lipid peroxidation","volume":"34","author":"Knight","year":"1998","journal-title":"Clin. Chem."},{"key":"10.1016\/j.neulet.2006.10.024_bib7","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0891-5849(89)90016-6","article-title":"Potential thiobarbituric acid-reactive substances in peroxidized lipids","volume":"7","author":"Kosugi","year":"1989","journal-title":"Free Radic. Biol. Ad. Med."},{"key":"10.1016\/j.neulet.2006.10.024_bib8","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1203\/01.PDR.0000102702.39608.82","article-title":"Relationship between cerebral interstitial levels of amino acids and phosphorylation potential during secondary energy failure in hypoxic-ischemic newborn piglets","volume":"55","author":"Kusaka","year":"2004","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.neulet.2006.10.024_bib9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0361-9230(98)00170-1","article-title":"Cellular mechanism of hypoxic injury in the developing brain","volume":"48","author":"Mishra","year":"1998","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.neulet.2006.10.024_bib10","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/S0006-8993(99)02404-X","article-title":"Free radicals are involved in the damage to protein synthesis after anoxia\/aglycemia and NMDA exposure","volume":"857","author":"Monje","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.neulet.2006.10.024_bib11","first-page":"R267","article-title":"Effects of hypoxia and ambient temperature on gaseous metabolism of newborn rats","volume":"263","author":"Mortola","year":"1992","journal-title":"Am. J. Physio."},{"key":"10.1016\/j.neulet.2006.10.024_bib12","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/0006-8993(89)91234-1","article-title":"Increased dopamine and serotonin metabolism in rat nucleus accumbens produced by intracranial self-stimulation of medial forebrain bundle as measured by in vivo microdialysis","volume":"495","author":"Nakahara","year":"1989","journal-title":"Brain Res."},{"key":"10.1016\/j.neulet.2006.10.024_bib13","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1161\/01.STR.0000185653.49740.c6","article-title":"Short-term administration of a new free radical scavenger, edaravone, is more effective than its long-term administration for the treatment of neonatal hypoxic-ischemic encephalopathy","volume":"36","author":"Noor","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.024_bib14","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/j.ajog.2005.03.069","article-title":"A free radical scavenger, edaravone, inhibits lipid peroxidation and the production of nitric oxide in hypoxic-ischemic brain damage of neonatal rats","volume":"193","author":"Noor","year":"2005","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.neulet.2006.10.024_bib15","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0168-0102(97)00111-9","article-title":"Nitric oxide contributes to irreversible membrane dysfunction caused by experimental ischemia in rat hippocampal CA1 neurons","volume":"30","author":"Onitsuka","year":"1998","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.neulet.2006.10.024_bib16","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1472-6882-4-11","article-title":"Rubia cordifolia, Fagonia cretica linn and Tinospora cordifolia exert neuroprotection by modulating the antioxidant system in rat hippocampal slices subjected to oxygen glucose deprivation","volume":"4","author":"Rawal","year":"2004","journal-title":"B.M.C. Complement Altern. Med."},{"key":"10.1016\/j.neulet.2006.10.024_bib17","doi-asserted-by":"crossref","first-page":"3213","DOI":"10.1152\/jn.00542.2003","article-title":"Arachidonic acid metabolites contribute to the irreversible depolarization induced by in vitro ischemia","volume":"90","author":"Tanaka","year":"2000","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neulet.2006.10.024_bib18","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s00221-002-1224-4","article-title":"Glutamate excess and free radical formation during and following kainic acid-induced status epilepticus","volume":"147","author":"Ueda","year":"2002","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.neulet.2006.10.024_bib19","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S0920-1211(96)00901-1","article-title":"Generation of lipid radicals in the hippocampal extracellular space during kainic acid-induced seizures in rats","volume":"26","author":"Ueda","year":"1997","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.neulet.2006.10.024_bib20","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s00221-002-1224-4","article-title":"Generation of lipid radicals in the hippocampus of neonatal rats after acute hypoxic-ischemic brain damage","volume":"147","author":"Ueda","year":"2006","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.neulet.2006.10.024_bib21","first-page":"1624","article-title":"Effects of an antistroke agent MCI-186 on cerebral arachidonate cascade","volume":"271","author":"Watanabe","year":"1994","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neulet.2006.10.024_bib22","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1080\/13510002.1996.11747069","article-title":"Antioxidant activity of 3-methyl-1phenyl-2pyrazolin-5-one","volume":"5","author":"Yamamoto","year":"1996","journal-title":"Redox. Rep."},{"key":"10.1016\/j.neulet.2006.10.024_bib23","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.devbrainres.2004.04.006","article-title":"Neuroprotection of edaravone on hypoxic-ischemic brain injury in neonatal rats","volume":"151","author":"Yasuoka","year":"2004","journal-title":"Dev. Brain Res."},{"key":"10.1016\/j.neulet.2006.10.024_bib24","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/j.mri.2004.09.003","article-title":"EPR imaging to estimate the in vivo intracerebral reducing ability of mature rats after neonatal hypoxic-ischemic brain injury","volume":"22","author":"Yokoyama","year":"2004","journal-title":"Magn. Reson. Imaging"}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394006011050?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394006011050?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,20]],"date-time":"2020-04-20T01:02:23Z","timestamp":1587344543000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394006011050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["S0304394006011050"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2006.10.024","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2007,2]]}}}