{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T10:42:12Z","timestamp":1770547332917,"version":"3.49.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1016\/j.neulet.2006.10.050","type":"journal-article","created":{"date-parts":[[2006,11,28]],"date-time":"2006-11-28T15:30:53Z","timestamp":1164727853000},"page":"238-242","source":"Crossref","is-referenced-by-count":40,"title":["Combined neuroprotective effects of celecoxib and memantine in experimental intracerebral hemorrhage"],"prefix":"10.1016","volume":"411","author":[{"given":"Dong-In","family":"Sinn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon-Tae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kon","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keun-Hwa","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun-Cheol","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong-Min","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Kyu","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Kyu","family":"Roh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neulet.2006.10.050_bib1","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1161\/01.STR.0000143451.14228.ff","article-title":"Glutamate receptor blockade attenuates glucose hypermetabolism in perihematomal brain after experimental intracerebral hemorrhage in rat","volume":"35","author":"Ardizzone","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib2","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1161\/01.STR.29.12.2600","article-title":"Expression and vascular effects of cyclooxygenase-2 in brain","volume":"29","author":"Brian","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib3","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1161\/01.STR.30.4.905","article-title":"Guidelines for the management of spontaneous intracerebral hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association","volume":"30","author":"Broderick","year":"1999","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib4","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1161\/01.STR.24.7.987","article-title":"Volume of intracerebral hemorrhage: a powerful and easy-to-use predictor of 30-day mortality","volume":"24","author":"Broderick","year":"1993","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib5","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/S0306-4522(98)00163-8","article-title":"Neuroprotective concentrations of the N-methyl-d-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation","volume":"86","author":"Chen","year":"1998","journal-title":"Neuroscience"},{"key":"10.1016\/j.neulet.2006.10.050_bib6","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1097\/01.WCB.0000130866.25040.7D","article-title":"Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death","volume":"24","author":"Chu","year":"2004","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neulet.2006.10.050_bib7","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1161\/01.STR.0000125855.17686.6d","article-title":"Combination therapy in ischemic stroke: synergistic neuroprotective effects of memeantine and clenbuterol","volume":"35","author":"Culmsee","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib8","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0022-5223(99)70424-1","article-title":"Memantine for prevention of spinal cord injury in a rabbit model","volume":"117","author":"Ehrlich","year":"1999","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.neulet.2006.10.050_bib9","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1083\/jcb.119.3.493","article-title":"Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation","volume":"119","author":"Gavrieli","year":"1992","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.neulet.2006.10.050_bib10","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1161\/01.STR.0000035283.34109.EA","article-title":"Relative edema volume is a predictor of outcome in patients with hyperacute spontaneous intracerebral hemorrhage","volume":"33","author":"Gebel","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib11","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.jneuroim.2004.09.006","article-title":"Additive effect of the combination of glatiramer acetate and minocycline in a model of MS","volume":"158","author":"Giuliani","year":"2005","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.neulet.2006.10.050_bib12","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0006-8993(01)02186-2","article-title":"Inducible cyclooxygenase-2 expression after experimental intracerebral hemorrhage","volume":"901","author":"Gong","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.neulet.2006.10.050_bib13","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1001\/archneur.60.4.628","article-title":"Cyclooxygenases in central nervous system disease: a special role for cyclooxygenase 2 in neuronal cell death","volume":"60","author":"Graham","year":"2003","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.neulet.2006.10.050_bib14","first-page":"206","article-title":"The structure of mammalian cyclooxygenases","volume":"32","author":"Gravito","year":"2003","journal-title":"Annu. Rev. Biophys. Biomol. Struct."},{"key":"10.1016\/j.neulet.2006.10.050_bib15","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1023\/A:1018856020583","article-title":"Brain penetration and in vivo recovery of NMDA receptor antagonists amantadine and memantine: a quantitative microdialysis study","volume":"16","author":"Hesselink","year":"1999","journal-title":"Pharm. Res."},{"key":"10.1016\/j.neulet.2006.10.050_bib16","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1161\/01.STR.0000032302.91894.0F","article-title":"Behavioral tests after intracerebral hemorrhage in the rat","volume":"33","author":"Hua","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib17","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1073\/pnas.98.3.1294","article-title":"Reduced susceptibility to ischemic brain injury and NMDA-mediated neurotoxicity in cyclooxygenase-2 deficeint mice","volume":"98","author":"Iadecola","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neulet.2006.10.050_bib18","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1161\/01.STR.0000083698.20199.1F","article-title":"Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage","volume":"34","author":"Jeong","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib19","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1161\/01.STR.0000131270.45822.85","article-title":"HMG-CoA reductase inhibitor, atorvastatin, promotes sensorimotor recovery, suppressing acute inflammatory reaction after experimental intracerebral hemorrhage","volume":"35","author":"Jung","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib20","doi-asserted-by":"crossref","first-page":"2704","DOI":"10.1161\/01.STR.0000096540.40826.BA","article-title":"Interactions between p38 mitogen-activated protein kinase and caspase-3 in cerebral endothelial cell death after hypoxia-reoxygenation","volume":"34","author":"Lee","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib21","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/sj.jcbfm.9600213","article-title":"Memantine reduces hematoma expansion in experimental intracerebral hemorrhage, resulting in functional improvement","volume":"26","author":"Lee","year":"2006","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neulet.2006.10.050_bib22","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/sj.cdd.4401344","article-title":"Paradigm shift in neuroprotective drug development: clinically tolerated NMDA receptor inhibition by memantine","volume":"11","author":"Lipton","year":"2004","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.neulet.2006.10.050_bib23","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1161\/01.STR.0000153069.96296.fd","article-title":"Exciting, radical, suicidal: how brain cells die after stroke","volume":"36","author":"Lo","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib24","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1002\/ana.20078","article-title":"Prostanoids, not reactive oxygen species, mediate COX-2-depedent neurotoxicity","volume":"55","author":"Manabe","year":"2004","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neulet.2006.10.050_bib25","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1097\/00004647-200002000-00022","article-title":"Evidence for apoptosis after intracerebral hemorrhage in rat striatum","volume":"20","author":"Matsushita","year":"2000","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neulet.2006.10.050_bib26","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1056\/NEJMoa042991","article-title":"Recombinant activated factor VII for acute intracerebral hemorrhage","volume":"352","author":"Mayer","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.neulet.2006.10.050_bib27","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/S1474-4422(05)70195-2","article-title":"Treatment of intracerebral hemorrhage","volume":"4","author":"Mayer","year":"2005","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.neulet.2006.10.050_bib28","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S0140-6736(05)17826-X","article-title":"Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial","volume":"365","author":"Mendelow","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.neulet.2006.10.050_bib29","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0028-3908(99)00019-2","article-title":"Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist\u2014a review of preclinical data","volume":"38","author":"Parson","year":"1999","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neulet.2006.10.050_bib30","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1097\/01.CCM.0000063047.63862.99","article-title":"Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study","volume":"31","author":"Qureshi","year":"2003","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.neulet.2006.10.050_bib31","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S0006-8993(01)02617-8","article-title":"Neuroprotection by memantine, a non-competitive NMDA receptor antagonist after traumatic brain injury in rats","volume":"911","author":"Rao","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.neulet.2006.10.050_bib32","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1056\/NEJMoa013128","article-title":"Memantine in moderate-to-severe Alzheimer's disease","volume":"348","author":"Reisberg","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.neulet.2006.10.050_bib33","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/00075198-200404000-00003","article-title":"Novel therapies for intracerebral hemorrhage","volume":"10","author":"Rincon","year":"2004","journal-title":"Curr. Opin. Crit. Care"},{"key":"10.1016\/j.neulet.2006.10.050_bib34","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1161\/01.STR.21.5.801","article-title":"Collagenase-induced intracerebral hemorrhage in rats","volume":"21","author":"Rosenberg","year":"1990","journal-title":"Stroke"},{"key":"10.1016\/j.neulet.2006.10.050_bib35","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1172\/JCI25805","article-title":"Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity","volume":"116","author":"St\u00fcve","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neulet.2006.10.050_bib36","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/3-211-30714-1_19","article-title":"Spontaneous intracerebral hemorrhage in humans: hematoma enlargement, clot lysis, and brain edema","volume":"96","author":"Wu","year":"2006","journal-title":"Acta Neurochir. Suppl."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394006011104?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304394006011104?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T08:59:06Z","timestamp":1547197146000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304394006011104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["S0304394006011104"],"URL":"https:\/\/doi.org\/10.1016\/j.neulet.2006.10.050","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[2007,1]]}}}